Detailed information for compound 44762

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 555.623 | Formula: C28H37N5O7
  • H donors: 6 H acceptors: 7 LogP: -0.67 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 3
  • SMILES: O=C1CNC(=O)C(CCCCNC(=O)C(N1)Cc1ccccc1)NC(=O)C(Cc1ccc(cc1)O)[NH3+].[O-]C(=O)C
  • InChi: 1S/C26H33N5O5.C2H4O2/c27-20(14-18-9-11-19(32)12-10-18)24(34)31-21-8-4-5-13-28-26(36)22(15-17-6-2-1-3-7-17)30-23(33)16-29-25(21)35;1-2(3)4/h1-3,6-7,9-12,20-22,32H,4-5,8,13-16,27H2,(H,28,36)(H,29,35)(H,30,33)(H,31,34);1H3,(H,3,4)
  • InChiKey: NGEIZKGBTUEZOD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0015 0.0012 0.0013
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0032 0.0034
Leishmania major protein kinase, putative 0.0526 0.226 1
Echinococcus multilocularis neuropeptide Y receptor 0.0124 0.0493 0.053
Echinococcus multilocularis carbonic anhydrase 0.0174 0.0712 0.0766
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0414 0.1769 1
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Brugia malayi sulfakinin receptor protein 0.0124 0.0493 0.1214
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0043 0.0137 0.0566
Echinococcus granulosus integrin linked protein kinase 0.0526 0.226 0.2432
Loa Loa (eye worm) TK/FER protein kinase 0.0526 0.226 0.5627
Entamoeba histolytica hypothetical protein 0.0526 0.226 0.5594
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0144 0.0345
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0032 0.0034
Echinococcus multilocularis sex peptide receptor 0.0124 0.0493 0.053
Echinococcus granulosus g protein coupled receptor 0.0124 0.0493 0.053
Echinococcus multilocularis g-protein coupled receptor 0.0124 0.0493 0.053
Onchocerca volvulus 0.0925 0.4016 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0526 0.226 0.5594
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0029 0.0056
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0399 0.1701 0.1696
Echinococcus granulosus ephrin type A receptor 4 A 0.0526 0.226 0.2432
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0019 0.003 0.0198
Leishmania major adenosine kinase, putative 0.0518 0.2224 0.9839
Loa Loa (eye worm) TK/EPH protein kinase 0.0526 0.226 0.5627
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0414 0.1769 0.4397
Loa Loa (eye worm) CXXC zinc finger family protein 0.0056 0.0192 0.0478
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Schistosoma mansoni amine GPCR 0.0124 0.0493 0.0487
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0009 0.0007
Brugia malayi Dopamine receptor protein 1 0.0124 0.0493 0.1214
Trypanosoma cruzi adenosine kinase, putative 0.0059 0.0205 0.0867
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Trichomonas vaginalis D-aminoacylase, putative 0.0033 0.0091 0.0376
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0414 0.1769 0.782
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0034 0.0097 0.0104
Schistosoma mansoni serine/threonine protein kinase 0.0526 0.226 0.2255
Entamoeba histolytica hypothetical protein 0.0526 0.226 0.5594
Loa Loa (eye worm) hypothetical protein 0.0887 0.3849 0.9585
Echinococcus multilocularis geminin 0.0336 0.1425 0.1534
Schistosoma mansoni protein kinase 0.0526 0.226 0.2255
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Schistosoma mansoni sodium-dependent amino acid transporter 0.0151 0.0608 0.0602
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0526 0.226 0.2432
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0817 0.0811
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0399 0.1701 0.1831
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0887 0.3849 0.3845
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.008
Loa Loa (eye worm) TK/FER protein kinase 0.0925 0.4016 1
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.025 0.1048 0.4375
Echinococcus multilocularis tyrosine kinase 0.0925 0.4016 0.4323
Brugia malayi CXXC zinc finger family protein 0.0056 0.0192 0.0464
Echinococcus granulosus protein tyrosine kinase 0.0526 0.226 0.2432
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0019 0.003 0.0198
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0427 0.1062
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0017 0.0011
Brugia malayi Pax transcription factor protein 2 0.0235 0.0982 0.2433
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0469 0.201 0.8891
Loa Loa (eye worm) hypothetical protein 0.0526 0.226 0.5627
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0144 0.0138
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0526 0.226 0.2432
Brugia malayi integrin-linked kinase 0.0526 0.226 0.562
Loa Loa (eye worm) aspartyl protease 6 0.0198 0.0817 0.2035
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0414 0.1769 0.1904
Schistosoma mansoni lamin 0.0026 0.0059 0.0052
Echinococcus multilocularis FL cytokine receptor 0.0526 0.226 0.2432
Giardia lamblia Ribokinase 0.0059 0.0205 0.0593
Echinococcus multilocularis carbonic anhydrase 0.0174 0.0712 0.0766
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Brugia malayi putative neuropeptide receptor 0.0124 0.0493 0.1214
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0013 0.0014
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0493 0.053
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0143 0.0574 0.1417
Trypanosoma brucei adenosine transporter, putative 0.0043 0.0137 0.0564
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Brugia malayi Receptor family ligand binding region containing protein 0.0529 0.2274 0.5656
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0493 0.053
Schistosoma mansoni shc transforming protein 0.0399 0.1701 0.1696
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0022 0.0024
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0526 0.226 0.5594
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0006 0.0015
Echinococcus granulosus SHC transforming protein 3 0.0399 0.1701 0.1831
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0043 0.0137 0.0566
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0124 0.0493 0.053
Brugia malayi larval opioid receptor 0.0124 0.0493 0.1214
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0059 0.0147
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0043 0.0137 0.0564
Echinococcus granulosus natriuretic peptide receptor 1 0.0526 0.226 0.2432
Trichomonas vaginalis ferritin, putative 0.0027 0.0062 0.0254
Leishmania major nucleobase transporter 0.0043 0.0137 0.0564
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0414 0.1769 0.1764
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0414 0.1769 0.7384
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0529 0.2274 0.2448
Brugia malayi Protein kinase domain containing protein 0.0925 0.4016 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0124 0.0493 0.053
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0526 0.226 0.9443
Schistosoma mansoni protein kinase 0.0043 0.0137 0.013
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0526 0.226 0.2255
Trypanosoma brucei adenosine transporter 2, putative 0.0043 0.0137 0.0564
Echinococcus granulosus beta LACTamase domain containing family member 0.0033 0.0091 0.0098
Mycobacterium ulcerans lipase LipD 0.0033 0.0091 0.035
Echinococcus granulosus tyrosine kinase 0.0526 0.226 0.2432
Loa Loa (eye worm) TK/FER protein kinase 0.0925 0.4016 1
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0043 0.0137 0.0564
Trypanosoma cruzi ribokinase, putative 0.0059 0.0205 0.0867
Onchocerca volvulus 0.0124 0.0493 0.1208
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0414 0.1769 0.1764
Mycobacterium ulcerans 6-phosphofructokinase 0.0109 0.0427 0.2279
Schistosoma mansoni biogenic amine (5HT) receptor 0.0124 0.0493 0.0487
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0414 0.1769 0.1764
Echinococcus multilocularis mothers against decapentaplegic 5 0.0015 0.0012 0.0013
Echinococcus granulosus lamin dm0 0.0026 0.0059 0.0063
Echinococcus granulosus tyrosine protein kinase HCK 0.0526 0.226 0.2432
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0075 0.0278
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0124 0.0493 0.053
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0054 0.0196
Echinococcus multilocularis ephrin type A receptor 4 A 0.0526 0.226 0.2432
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0526 0.226 0.2255
Schistosoma mansoni microtubule-associated protein tau 0.2123 0.929 0.929
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0526 0.226 0.9441
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Schistosoma mansoni hypothetical protein 0.0124 0.0493 0.0487
Brugia malayi hypothetical protein 0.0124 0.0493 0.1214
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0399 0.1701 0.1831
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Onchocerca volvulus 0.0526 0.226 0.5617
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Entamoeba histolytica SH2 domain containing protein 0.0399 0.1701 0.4192
Onchocerca volvulus 0.0529 0.2274 0.5653
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0128 0.051 0.2225
Leishmania major hypothetical protein, conserved 0.0156 0.0633 0.2772
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0526 0.226 0.5594
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0032 0.0065
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0817 0.0811
Brugia malayi STAT protein, DNA binding domain containing protein 0.0529 0.2273 0.5653
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0414 0.1769 0.4554
Plasmodium vivax plasmepsin IV, putative 0.0556 0.2393 1
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0414 0.1769 0.7392
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0109 0.0427 0.1038
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Brugia malayi SH2 domain containing protein 0.0399 0.1701 0.4228
Echinococcus multilocularis receptor type guanylyl cyclase 0.0529 0.2274 0.2448
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0094 0.0358 0.1547
Entamoeba histolytica hypothetical protein 0.0526 0.226 0.5594
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0925 0.4016 0.4323
Echinococcus granulosus ribokinase 0.0059 0.0205 0.022
Brugia malayi G protein-coupled receptor 0.0124 0.0493 0.1214
Schistosoma mansoni neuropeptide receptor 0.0124 0.0493 0.0487
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0526 0.226 0.2432
Brugia malayi SH2 domain containing protein 0.0399 0.1701 0.4228
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus granulosus tyrosine protein kinase Blk 0.0925 0.4016 0.4323
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0493 0.0487
Echinococcus granulosus neuropeptides capa receptor 0.0124 0.0493 0.053
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0526 0.226 0.5627
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0013 0.0014
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus granulosus tyrosine protein kinase shark 0.0925 0.4016 0.4323
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0526 0.226 0.562
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0032 0.0026
Loa Loa (eye worm) hypothetical protein 0.0526 0.226 0.5627
Loa Loa (eye worm) hypothetical protein 0.0017 0.002 0.0051
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0526 0.226 0.562
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0427 0.1779
Loa Loa (eye worm) TK/FAK protein kinase 0.0526 0.226 0.5627
Brugia malayi beta-lactamase family protein 0.0033 0.0091 0.0212
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0128 0.051 0.2225
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0124 0.0493 0.053
Chlamydia trachomatis endonuclease IV 0.0077 0.0285 0.1463
Echinococcus granulosus sex peptide receptor 0.0124 0.0493 0.053
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0526 0.226 0.2432
Echinococcus multilocularis tyrosine protein kinase Srms 0.0925 0.4016 0.4323
Echinococcus granulosus SH2 motif 0.0399 0.1701 0.1831
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0529 0.2274 0.2448
Echinococcus multilocularis bloom syndrome protein 0.0021 0.004 0.0043
Onchocerca volvulus 0.0198 0.0817 0.2018
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0013 0.0014
Onchocerca volvulus 0.0033 0.0091 0.0205
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0075 0.0118
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0469 0.201 0.2005
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0032 0.0034
Toxoplasma gondii nucleoside transporter protein 0.0043 0.0137 0.0538
Schistosoma mansoni smad1 5 8 and 0.0015 0.0012 0.0006
Mycobacterium tuberculosis Probable integral membrane protein 0.0019 0.003 0.0198
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Schistosoma mansoni hypothetical protein 0.0014 0.0009 0.0002
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.002 0.0049
Trypanosoma cruzi nucleoside transporter 1, putative 0.0043 0.0137 0.0564
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0151 0.0608 0.0654
Echinococcus granulosus dnaJ subfamily B 0.0799 0.3462 0.3726
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0033 0.0091 0.0227
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Trichomonas vaginalis ribokinase, putative 0.0059 0.0205 0.0852
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Brugia malayi SH2 domain containing protein 0.0925 0.4016 1
Loa Loa (eye worm) TK/FER protein kinase 0.0925 0.4016 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0925 0.4016 0.4323
Brugia malayi Protein kinase domain containing protein 0.0925 0.4016 1
Giardia lamblia Hypothetical protein 0.025 0.1048 0.445
Onchocerca volvulus 0.0072 0.0263 0.0634
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0526 0.226 0.562
Trypanosoma brucei nucleoside transporter 1, putative 0.0043 0.0137 0.0564
Schistosoma mansoni ferritin 0.0027 0.0062 0.0055
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Brugia malayi hypothetical protein 0.0526 0.226 0.562
Plasmodium falciparum plasmepsin III 0.0198 0.0817 0.3379
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) hypothetical protein 0.025 0.1048 0.2609
Loa Loa (eye worm) hypothetical protein 0.0151 0.0608 0.1514
Brugia malayi SH2 domain containing protein 0.0925 0.4016 1
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0399 0.1701 0.4236
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Echinococcus multilocularis tyrosine protein kinase shark 0.0925 0.4016 0.4323
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0062 0.0218 0.0529
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0062 0.0218 0.0235
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Onchocerca volvulus 0.0925 0.4016 1
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0526 0.226 0.2432
Loa Loa (eye worm) TK/ALK protein kinase 0.0526 0.226 0.5627
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus multilocularis Ankyrin 0.0015 0.0009 0.001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0144 0.0138
Echinococcus granulosus retinal guanylyl cyclase 2 0.0529 0.2274 0.2448
Loa Loa (eye worm) G-protein coupled receptor 0.0124 0.0493 0.1227
Trypanosoma cruzi adenosine kinase, putative 0.0059 0.0205 0.0867
Plasmodium vivax protease, putative 0.0019 0.003 0.0089
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0032 0.0034
Trichomonas vaginalis D-aminoacylase, putative 0.0033 0.0091 0.0376
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0151 0.0608 0.1501
Loa Loa (eye worm) hypothetical protein 0.0887 0.3849 0.9585
Echinococcus multilocularis musashi 0.0026 0.0059 0.0063
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0001 0.000000000067265
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0399 0.1701 0.4236
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0526 0.226 0.2432
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0526 0.226 0.2255
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0075 0.031
Trichomonas vaginalis esterase, putative 0.0033 0.0091 0.0376
Echinococcus multilocularis protein KINase family member (kin 25) 0.0526 0.226 0.2432
Plasmodium falciparum plasmepsin II 0.0556 0.2393 1
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0414 0.1769 0.782
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0151 0.0608 0.0654
Schistosoma mansoni protein kinase 0.0526 0.226 0.2255
Trichomonas vaginalis lipase containing protein, putative 0.0156 0.0633 0.2643
Brugia malayi Adenosine kinase-like 0.0518 0.2224 0.553
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0059 0.0132
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0526 0.226 0.5594
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0124 0.0493 0.053
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0014 0.0006 0.0007
Schistosoma mansoni SH2A 0.0399 0.1701 0.1696
Loa Loa (eye worm) histone methyltransferase 0.0017 0.0021 0.0054
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0526 0.226 0.2432
Brugia malayi Furin-like cysteine rich region family protein 0.0526 0.226 0.562
Echinococcus multilocularis ribokinase 0.0059 0.0205 0.022
Schistosoma mansoni coup transcription factor 0.002 0.0032 0.0026
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0414 0.1769 0.1904
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0244 0.0609
Toxoplasma gondii protein kinase domain-containing protein 0.0526 0.226 0.9441
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0003
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0021 0.0023
Brugia malayi follicle stimulating hormone receptor 0.0356 0.1512 0.3755
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0032 0.0058
Echinococcus multilocularis activated cdc42 kinase 1 0.0526 0.226 0.2432
Brugia malayi Protein kinase domain containing protein 0.0925 0.4016 1
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0075 0.0258
Echinococcus multilocularis activin receptor type 0.0526 0.226 0.2432
Brugia malayi aspartic protease BmAsp-2, identical 0.0198 0.0817 0.2023
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0075 0.0258
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0151 0.0608 0.2514
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0271 0.114 0.2839
Onchocerca volvulus 0.0399 0.1701 0.4224
Echinococcus granulosus expressed protein 0.0027 0.0062 0.0066
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0925 0.4016 0.4323
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0075 0.0281
Brugia malayi G protein-coupled receptor F59B2.13 0.0124 0.0493 0.1214
Echinococcus multilocularis adenylate cyclase 9 0.0075 0.0277 0.0298
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0526 0.226 0.5594
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.008
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0526 0.226 0.5627
Brugia malayi hypothetical protein 0.0124 0.0493 0.1214
Schistosoma mansoni GTPase activating protein 0.0399 0.1701 0.1696
Schistosoma mansoni protein tyrosine kinase 0.0529 0.2274 0.2269
Echinococcus multilocularis g protein coupled receptor 0.0124 0.0493 0.053
Loa Loa (eye worm) MH1 domain-containing protein 0.0015 0.0012 0.0031
Toxoplasma gondii protein kinase 0.0526 0.226 0.9441
Loa Loa (eye worm) hypothetical protein 0.025 0.1048 0.2609
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0023
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus granulosus GPCR family 2 0.0062 0.0218 0.0235
Schistosoma mansoni serine/threonine protein kinase 0.0526 0.226 0.2255
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0526 0.226 0.5594
Trypanosoma brucei ribokinase, putative 0.0059 0.0205 0.0867
Echinococcus multilocularis tensin 0.0399 0.1701 0.1831
Echinococcus multilocularis raf serine:threonine protein kinase 0.0526 0.226 0.2432
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0032 0.0026
Brugia malayi Serotonin receptor 0.0124 0.0493 0.1214
Loa Loa (eye worm) TK/ROR protein kinase 0.0526 0.226 0.5627
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Leishmania major tagatose-6-phosphate kinase-like protein 0.0059 0.0205 0.0867
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Onchocerca volvulus 0.0151 0.0608 0.1495
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0244 0.0263
Onchocerca volvulus 0.0925 0.4016 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0493 0.053
Brugia malayi hypothetical protein 0.0198 0.0817 0.2023
Leishmania major nucleoside transporter 1, putative 0.0043 0.0137 0.0564
Onchocerca volvulus Tyrosine kinase homolog 0.0526 0.226 0.5617
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0124 0.0493 0.053
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0032 0.0065
Echinococcus granulosus microtubule associated protein 2 0.2123 0.929 1
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0469 0.201 0.2005
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Loa Loa (eye worm) TK/FER protein kinase 0.0526 0.226 0.5627
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0033 0.0091 0.0227
Schistosoma mansoni apoferritin-2 0.0027 0.0062 0.0055
Echinococcus multilocularis fmrfamide receptor 0.0124 0.0493 0.053
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0075 0.0281
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0124 0.0493 0.053
Loa Loa (eye worm) TK/INSR protein kinase 0.0526 0.226 0.5627
Brugia malayi Guanylyl cyclase protein 23 0.0529 0.2274 0.5656
Schistosoma mansoni carbonic anhydrase-related 0.0174 0.0712 0.0706
Echinococcus multilocularis integrin linked protein kinase 0.0526 0.226 0.2432
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0077 0.0285 0.3141
Echinococcus granulosus tumor protein p63 0.038 0.1616 0.1739
Brugia malayi hypothetical protein 0.0124 0.0493 0.1214
Entamoeba histolytica hypothetical protein 0.0526 0.226 0.5594
Echinococcus granulosus tm gpcr rhodopsin 0.0124 0.0493 0.053
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus granulosus neuropeptide FF receptor 2 0.0124 0.0493 0.053
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0286 0.1204 0.2999
Echinococcus multilocularis neuropeptide FF receptor 2 0.0124 0.0493 0.053
Echinococcus granulosus tyrosine protein kinase Lyn 0.0925 0.4016 0.4323
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Echinococcus granulosus mixed lineage leukemia protein mll 0.0014 0.0006 0.0007
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0032 0.0034
Echinococcus multilocularis transfer RNA-Thr 0.0526 0.226 0.2432
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0143 0.0575 0.6502
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0526 0.226 0.5617
Toxoplasma gondii aspartyl protease ASP3 0.0198 0.0817 0.3392
Brugia malayi Variant SH3 domain containing protein 0.0399 0.1701 0.4228
Echinococcus multilocularis SHC transforming protein 3 0.0399 0.1701 0.1831
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0032 0.0026
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0151 0.0608 0.0654
Echinococcus granulosus neuropeptide receptor 0.0124 0.0493 0.053
Echinococcus multilocularis tyrosine protein kinase Blk 0.0925 0.4016 0.4323
Loa Loa (eye worm) TK protein kinase 0.0526 0.226 0.5627
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0526 0.226 0.5594
Plasmodium falciparum plasmepsin VI 0.0556 0.2393 1
Echinococcus granulosus neuropeptide s receptor 0.0124 0.0493 0.053
Plasmodium falciparum transporter, putative 0.0151 0.0608 0.2499
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) TK/FER protein kinase 0.0526 0.226 0.5627
Loa Loa (eye worm) hypothetical protein 0.0206 0.0851 0.2118
Brugia malayi SH2 domain containing protein 0.0399 0.1701 0.4228
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0124 0.0493 0.053
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0526 0.226 1
Entamoeba histolytica nucleoside transporter, putative 0.0043 0.0137 0.0267
Echinococcus granulosus tyrosine protein kinase Fyn 0.0925 0.4016 0.4323
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Brugia malayi Raf kinase 0.0526 0.226 0.562
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0124 0.0493 0.0487
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0075 0.0277 0.0669
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0414 0.1769 0.7392
Loa Loa (eye worm) hypothetical protein 0.0056 0.019 0.0472
Loa Loa (eye worm) hypothetical protein 0.0151 0.0608 0.1514
Loa Loa (eye worm) SH2 domain-containing protein 0.0399 0.1701 0.4236
Brugia malayi Serotonin receptor 0.0124 0.0493 0.1214
Brugia malayi Protein kinase domain containing protein 0.0014 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0056
Trypanosoma brucei Flagellum attachment zone protein 20 0.0526 0.226 1
Onchocerca volvulus 0.0075 0.0277 0.0669
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Plasmodium vivax protein kinase, putative 0.0526 0.226 0.9441
Schistosoma mansoni tyrosine kinase 0.0925 0.4016 0.4012
Mycobacterium ulcerans bacterioferritin BfrA 0.0027 0.0062 0.0181
Plasmodium falciparum carbonic anhydrase 0.0174 0.0712 0.2936
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Trypanosoma cruzi nucleoside transporter-like, putative 0.0043 0.0137 0.0564
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0427 0.0994
Brugia malayi MH1 domain containing protein 0.0015 0.0012 0.0016
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0009 0.0002
Echinococcus granulosus tachykinin peptides receptor 99D 0.0124 0.0493 0.053
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Echinococcus granulosus tyrosine protein kinase Src42A 0.0399 0.1701 0.1831
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0033 0.0091 0.0212
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0526 0.226 0.2432
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.008
Echinococcus multilocularis kinase suppressor of Ras 1 0.0526 0.226 0.2432
Entamoeba histolytica ankyrin repeat protein 0.0526 0.226 0.5594
Echinococcus multilocularis SH2 motif 0.0399 0.1701 0.1831
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Brugia malayi Bromodomain containing protein 0.0037 0.0107 0.0251
Brugia malayi Variant SH3 domain containing protein 0.0399 0.1701 0.4228
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0015 0.0012 0.0006
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.004 0.0084
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0077 0.0285 0.0695
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0414 0.1769 0.4363
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0817 0.0811
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0174 0.0712 0.176
Plasmodium falciparum protease, putative 0.0019 0.003 0.0072
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0033 0.0091 0.0085
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0032 0.0034
Loa Loa (eye worm) transcription factor SMAD2 0.0224 0.0933 0.2322
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0526 0.226 0.2255
Entamoeba histolytica tyrosin kinase, putative 0.0526 0.226 0.5594
Onchocerca volvulus 0.0033 0.0091 0.0205
Plasmodium falciparum plasmepsin I 0.0556 0.2393 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0013 0.0017
Loa Loa (eye worm) hypothetical protein 0.0526 0.226 0.5627
Schistosoma mansoni ephrin receptor 0.0526 0.226 0.2255
Echinococcus multilocularis 0.0399 0.1701 0.1831
Trypanosoma brucei adenosine transporter, putative 0.0043 0.0137 0.0564
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0526 0.226 0.5594
Echinococcus multilocularis g protein coupled receptor 0.0124 0.0493 0.053
Echinococcus granulosus tyrosine protein kinase ABL1 0.0925 0.4016 0.4323
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.008
Onchocerca volvulus 0.0124 0.0493 0.1208
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Brugia malayi hypothetical protein 0.0198 0.0817 0.2023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0001 0.000000000067265
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Trichomonas vaginalis protein kinase atn1, putative 0.0526 0.226 0.9443
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Brugia malayi C-terminal src kinase protein 1 0.0526 0.226 0.562
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0427 0.1853
Loa Loa (eye worm) latrophilin receptor protein 2 0.0062 0.0218 0.0543
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.0059 0.0205 0.022
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0399 0.1701 0.4236
Brugia malayi SH2 domain containing protein 0.0399 0.1701 0.4228
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0151 0.0608 0.1501
Brugia malayi hypothetical protein 0.0035 0.01 0.0234
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0414 0.1769 0.1904
Loa Loa (eye worm) G-protein coupled receptor 0.0124 0.0493 0.1227
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0124 0.0493 0.0487
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0244 0.0238
Entamoeba histolytica hypothetical protein 0.0526 0.226 0.5594
Echinococcus granulosus tyrosine protein kinase Src64B 0.0925 0.4016 0.4323
Echinococcus multilocularis neuropeptide receptor 0.0124 0.0493 0.053
Echinococcus granulosus expressed conserved protein 0.0399 0.1701 0.1831
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus multilocularis sodium and chloride dependent glycine 0.0151 0.0608 0.0654
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0399 0.1701 0.4236
Echinococcus granulosus activated cdc42 kinase 1 0.0526 0.226 0.2432
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0032 0.0034
Brugia malayi nuclear receptor NHR-88 0.002 0.0032 0.0065
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0414 0.1769 0.782
Onchocerca volvulus 0.0026 0.0059 0.0125
Echinococcus granulosus Smad4 0.0015 0.0012 0.0013
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0469 0.201 0.4998
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0091 0.0362
Loa Loa (eye worm) TK protein kinase 0.0526 0.226 0.5627
Mycobacterium leprae Probable adenosine kinase adk 0.0059 0.0205 0.315
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0054 0.0196
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0054 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0925 0.4016 0.4323
Brugia malayi hypothetical protein 0.0925 0.4016 1
Echinococcus granulosus suppressor of cytokine signaling 7 0.0399 0.1701 0.1831
Echinococcus granulosus neuropeptide Y receptor 0.0124 0.0493 0.053
Loa Loa (eye worm) RecQ helicase 0.0021 0.004 0.0099
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Loa Loa (eye worm) hypothetical protein 0.0033 0.0091 0.0227
Schistosoma mansoni tyrosine protein kinase 0.0526 0.226 0.2255
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0001 0.000000000067265
Entamoeba histolytica receptor protein kinase, putative 0.0526 0.226 0.5594
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Loa Loa (eye worm) TK/FER protein kinase 0.0925 0.4016 1
Brugia malayi Smad1 0.0015 0.0012 0.0016
Echinococcus granulosus hypothetical protein 0.0399 0.1701 0.1831
Trypanosoma brucei adenosine kinase, putative 0.0518 0.2224 0.9839
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0001 0.000000000067265
Schistosoma mansoni hypothetical protein 0.0174 0.0712 0.0706
Trypanosoma cruzi hypothetical protein, conserved 0.0156 0.0633 0.2772
Loa Loa (eye worm) TK/FER protein kinase 0.0526 0.226 0.5627
Echinococcus granulosus ferritin 0.0027 0.0062 0.0066
Brugia malayi intermediate filament protein 0.0026 0.0059 0.0132
Leishmania major inosine-guanosine transporter;with=GeneDB:LinJ36_V3.2040 0.0043 0.0137 0.0564
Schistosoma mansoni hypothetical protein 0.0399 0.1701 0.1696
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0144 0.0156
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Brugia malayi Immunoglobulin I-set domain containing protein 0.0526 0.226 0.562
Onchocerca volvulus 0.0526 0.226 0.5617
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0013 0.0016
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0054 0.017
Loa Loa (eye worm) TK protein kinase 0.0526 0.226 0.5627
Brugia malayi PHD-finger family protein 0.0027 0.0064 0.0145
Brugia malayi MH2 domain containing protein 0.0015 0.0012 0.0016
Schistosoma mansoni hypothetical protein 0.0062 0.0218 0.0212
Echinococcus granulosus carbonic anhydrase 0.0174 0.0712 0.0766
Trypanosoma brucei Pseudokinase, putative 0.0526 0.226 1
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.025 0.1048 0.4375
Brugia malayi SH2 domain containing protein 0.0399 0.1701 0.4228
Schistosoma mansoni tensin-related 0.0399 0.1701 0.1696
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0414 0.1769 0.782
Trypanosoma brucei nucleoside transporter 1, putative 0.0043 0.0137 0.0564
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0054 0.017
Toxoplasma gondii ABC1 family protein 0.0033 0.0091 0.0347
Entamoeba histolytica hypothetical protein 0.0526 0.226 0.5594
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0124 0.0493 0.0487
Loa Loa (eye worm) TK protein kinase 0.0526 0.226 0.5627
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Echinococcus multilocularis tyrosine protein kinase csk 0.0526 0.226 0.2432
Schistosoma mansoni tyrosine kinase 0.0925 0.4016 0.4012
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Trypanosoma brucei unspecified product 0.0043 0.0137 0.0564
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0034 0.0246
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0271 0.1139 0.502
Echinococcus granulosus allatostatin A receptor 0.0124 0.0493 0.053
Echinococcus multilocularis ferritin 0.0027 0.0062 0.0066
Brugia malayi hypothetical protein 0.0016 0.0015 0.0023
Schistosoma mansoni tyrosine kinase 0.0925 0.4016 0.4012
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) TK protein kinase 0.0526 0.226 0.5627
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0817 0.0811
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.01 0.0108
Echinococcus granulosus adenylate cyclase 9 0.0075 0.0277 0.0298
Echinococcus granulosus activated cdc42 kinase 1 0.0526 0.226 0.2432
Loa Loa (eye worm) hypothetical protein 0.0271 0.114 0.2839
Schistosoma mansoni apoferritin-2 0.0027 0.0062 0.0055
Echinococcus multilocularis epidermal growth factor receptor 0.0526 0.226 0.2432
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.004 0.0161
Loa Loa (eye worm) RGC/RGC protein kinase 0.0529 0.2274 0.5662
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Echinococcus granulosus tensin 0.0399 0.1701 0.1831
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0414 0.1769 0.7385
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0013 0.0014
Schistosoma mansoni tensin 0.0399 0.1701 0.1696
Brugia malayi hypothetical protein 0.0124 0.0493 0.1214
Schistosoma mansoni tyrosine kinase 0.0925 0.4016 0.4013
Giardia lamblia Kinase, NEK 0.0526 0.226 0.9998
Toxoplasma gondii nucleoside transporter protein 0.0043 0.0137 0.0538
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0034 0.0024
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0196 0.0808 0.2013
Echinococcus granulosus N chimaerin 0.0399 0.1701 0.1831
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0925 0.4016 0.4323
Mycobacterium tuberculosis Probable lipase LipE 0.0033 0.0091 0.0901
Brugia malayi aspartic protease BmAsp-1, identical 0.0198 0.0817 0.2023
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) SH2 domain-containing protein 0.0399 0.1701 0.4236
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0144 0.0156
Loa Loa (eye worm) hypothetical protein 0.0526 0.226 0.5627
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Mycobacterium leprae Probable lipase LipE 0.0033 0.0091 0.1048
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Loa Loa (eye worm) TK/Met protein kinase 0.0526 0.226 0.5627
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0526 0.226 0.5594
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0143 0.0575 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0075 0.031
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) hypothetical protein 0.0037 0.0107 0.0266
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) RGC/RGC protein kinase 0.0529 0.2274 0.5662
Brugia malayi CAAX amino terminal protease family protein 0.0094 0.0358 0.0877
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0925 0.4016 0.4323
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0151 0.0608 0.0602
Schistosoma mansoni lamin 0.0026 0.0059 0.0052
Loa Loa (eye worm) hypothetical protein 0.0039 0.0117 0.0291
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Brugia malayi 6-phosphofructokinase 0.0109 0.0427 0.1049
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0034 0.0071
Echinococcus granulosus tyrosine protein kinase 0.0526 0.226 0.2432
Loa Loa (eye worm) STAT protein 0.0529 0.2273 0.5659
Onchocerca volvulus 0.0526 0.226 0.5617
Brugia malayi SH2 domain containing protein 0.0399 0.1701 0.4228
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0427 0.0994
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0493 0.0487
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0925 0.4016 0.4323
Echinococcus multilocularis growth factor receptor bound protein 2 0.0399 0.1701 0.1831
Echinococcus granulosus sodium and chloride dependent glycine 0.0151 0.0608 0.0654
Leishmania major ATP-dependent phosphofructokinase 0.0109 0.0427 0.1853
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0556 0.2393 0.2388
Onchocerca volvulus 0.0124 0.0493 0.1208
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.008
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Trichomonas vaginalis penicillin-binding protein, putative 0.0033 0.0091 0.0376
Echinococcus granulosus receptor type guanylyl cyclase 0.0529 0.2274 0.2448
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0925 0.4016 0.4323
Trypanosoma cruzi nucleobase transporter, putative 0.0043 0.0137 0.0564
Echinococcus granulosus raf serine:threonine protein kinase 0.0526 0.226 0.2432
Mycobacterium tuberculosis Conserved protein 0.0033 0.0091 0.0901
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0399 0.1701 0.1831
Schistosoma mansoni hypothetical protein 0.0124 0.0493 0.0487
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0013 0.0014
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0094 0.0358 0.1491
Echinococcus granulosus fibroblast growth factor receptor 4 0.0526 0.226 0.2432
Mycobacterium ulcerans epimerase 0.002 0.0034 0.0024
Loa Loa (eye worm) hypothetical protein 0.0059 0.0205 0.051
Echinococcus granulosus g protein coupled receptor 0.0124 0.0493 0.053
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) hypothetical protein 0.0151 0.0608 0.1514
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0414 0.1769 0.782
Schistosoma mansoni equilibrative nucleoside transporter 0.0043 0.0137 0.013
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0032 0.008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0124 0.0493 0.0487
Giardia lamblia Kinase, NEK 0.0526 0.226 1
Loa Loa (eye worm) hypothetical protein 0.0518 0.2224 0.5537
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0526 0.226 0.5594
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0211 0.0227
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0013 0.0033
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0124 0.0493 0.1214
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0399 0.1701 0.1831
Echinococcus granulosus dro:myosuppressin receptor 0.0124 0.0493 0.053
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0526 0.226 0.2255
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Schistosoma mansoni protein kinase 0.0526 0.226 0.2255
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0151 0.0608 0.0602
Echinococcus multilocularis somatostatin receptor 0.0124 0.0493 0.053
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Onchocerca volvulus 0.0399 0.1701 0.4224
Leishmania major carbonic anhydrase-like protein 0.0469 0.201 0.8891
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0033 0.0091 0.0901
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Onchocerca volvulus 0.0235 0.0982 0.2428
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.004 0.0161
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus multilocularis protein tyrosine kinase 0.0526 0.226 0.2432
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0925 0.4016 0.4323
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Brugia malayi hypothetical protein 0.0124 0.0493 0.1214
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0013 0.0018
Brugia malayi Latrophilin receptor protein 2 0.0062 0.0218 0.0529
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0054 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0526 0.226 0.9443
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0244 0.0263
Loa Loa (eye worm) hypothetical protein 0.0174 0.0712 0.1773
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0399 0.1701 0.1696
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0151 0.0608 0.0602
Schistosoma mansoni hypothetical protein 0.0526 0.226 0.2255
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0034 0.0064
Brugia malayi Death domain containing protein 0.0014 0.0009 0.0007
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0033 0.0091 0.0901
Leishmania major hypothetical protein, conserved 0.0033 0.0091 0.0362
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0469 0.201 0.4998
Echinococcus multilocularis tyrosine protein kinase HCK 0.0526 0.226 0.2432
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0032 0.0026
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0271 0.1139 0.502
Entamoeba histolytica tyrosin kinase, putative 0.0526 0.226 0.5594
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0032 0.0065
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0094 0.0358 0.0352
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0414 0.1769 0.7753
Loa Loa (eye worm) hypothetical protein 0.025 0.1048 0.2609
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0399 0.1701 0.4224
Mycobacterium tuberculosis Adenosine kinase 0.0059 0.0205 0.2217
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0059 0.0147
Plasmodium falciparum tyrosine kinase-like protein 0.0526 0.226 0.944
Mycobacterium ulcerans hypothetical protein 0.002 0.0034 0.0024
Brugia malayi hypothetical protein 0.025 0.1048 0.2597
Leishmania major protein kinase, putative 0.0526 0.226 1
Entamoeba histolytica cysteine surface protein, putative 0.0526 0.226 0.5594
Echinococcus multilocularis serotonin transporter 0.0887 0.3849 0.4143
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0286 0.1204 0.2999
Trypanosoma brucei ribokinase, putative 0.0059 0.0205 0.0867
Echinococcus granulosus death domain containing protein 0.0014 0.0009 0.0009
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0526 0.226 0.5627
Echinococcus granulosus neuropeptide Y receptor 0.0124 0.0493 0.053
Echinococcus granulosus tyrosine protein kinase csk 0.0526 0.226 0.2432
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0399 0.1701 0.4228
Brugia malayi latrophilin 2 splice variant baaae 0.0134 0.0535 0.132
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0526 0.226 0.5594
Echinococcus multilocularis dnaJ subfamily B 0.0799 0.3462 0.3726
Schistosoma mansoni neuropeptide F-like receptor 0.0124 0.0493 0.0487
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0493 0.0487
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0124 0.0493 0.053
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Schistosoma mansoni protein kinase 0.0526 0.226 0.2255
Brugia malayi cytokine inducible SH2-containing protein 5 0.0399 0.1701 0.4228
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Echinococcus granulosus c src tyrosine kinase 0.0925 0.4016 0.4323
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Echinococcus multilocularis zinc finger protein 0.0022 0.0042 0.0045
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0244 0.1043
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0013 0.0016
Toxoplasma gondii hypothetical protein 0.0174 0.0712 0.2951
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0526 0.226 0.5594
Onchocerca volvulus 0.0026 0.0059 0.0125
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0086
Echinococcus granulosus g protein coupled receptor 0.0124 0.0493 0.053
Brugia malayi Variant SH3 domain containing protein 0.0399 0.1701 0.4228
Brugia malayi SRC-1 0.0925 0.4016 1
Onchocerca volvulus 0.0124 0.0493 0.1208
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0526 0.226 0.2432
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0526 0.226 1
Echinococcus granulosus tyrosine protein kinase csk 0.0526 0.226 0.2432
Schistosoma mansoni protein kinase 0.0526 0.226 0.2255
Entamoeba histolytica tyrosin kinase, putative 0.0526 0.226 0.5594
Echinococcus granulosus tyrosine protein kinase Srms 0.0925 0.4016 0.4323
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.008
Loa Loa (eye worm) TK/ACK protein kinase 0.0526 0.226 0.5627
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0054 0.0187
Schistosoma mansoni biogenic amine (5HT) receptor 0.0124 0.0493 0.0487
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0009 0.0022
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Echinococcus multilocularis tensin 0.0399 0.1701 0.1831
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0427 0.1779
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0032 0.0065
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0043 0.0137 0.0564
Schistosoma mansoni tensin-related 0.0399 0.1701 0.1696
Echinococcus multilocularis protein kinase 0.0526 0.226 0.2432
Echinococcus multilocularis G-protein coupled receptor, putative 0.0124 0.0493 0.053
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0001 0.000000000067265
Plasmodium falciparum protein kinase, putative 0.0526 0.226 0.944
Echinococcus granulosus 6 phosphofructokinase 0.0109 0.0427 0.0459
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0021 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0493 0.053
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0174 0.0712 0.176
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0054 0.0196
Mycobacterium ulcerans hypothetical protein 0.0033 0.0091 0.035
Schistosoma mansoni amine GPCR 0.0124 0.0493 0.0487
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0493 0.053
Echinococcus granulosus 7tm_1 domain containing protein 0.0124 0.0493 0.053
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0271 0.0292
Loa Loa (eye worm) pax transcription factor protein 2 0.0235 0.0982 0.2444
Echinococcus granulosus retinal guanylyl cyclase 2 0.0529 0.2274 0.2448
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Plasmodium vivax aspartyl proteinase, putative 0.0198 0.0817 0.339
Loa Loa (eye worm) hypothetical protein 0.0094 0.0358 0.0891
Loa Loa (eye worm) hypothetical protein 0.0925 0.4016 1
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0556 0.2393 0.5959
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0151 0.0608 0.0602
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0198 0.0817 0.3392
Echinococcus multilocularis heat shock protein 70 0.0526 0.226 0.2432
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0469 0.201 0.5006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0493 0.0487
Loa Loa (eye worm) hypothetical protein 0.0044 0.0139 0.0346
Echinococcus granulosus growth factor receptor bound protein 2 0.0399 0.1701 0.1831
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0399 0.1701 0.4192
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Trypanosoma cruzi adenosine kinase, putative 0.0518 0.2224 0.9839
Brugia malayi steroid hormone receptor 0.002 0.0032 0.0065
Trypanosoma cruzi adenosine kinase, putative 0.0518 0.2224 0.9839
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0075 0.031
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0414 0.1769 0.782
Brugia malayi Ribokinase 0.0059 0.0205 0.0496
Echinococcus multilocularis neuropeptide receptor A26 0.0124 0.0493 0.053
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0529 0.2274 0.2448
Mycobacterium tuberculosis Conserved protein 0.0033 0.0091 0.0901
Trypanosoma cruzi nucleoside transporter 1, putative 0.0043 0.0137 0.0564
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Schistosoma mansoni protein kinase 0.0526 0.226 0.2255
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Brugia malayi tRNA modification GTPase TrmE family protein 0.0399 0.1701 0.4228
Echinococcus granulosus carbonic anhydrase 0.0174 0.0712 0.0766
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0118 0.0127
Brugia malayi Tachykinin-like peptides receptor 99D 0.0124 0.0493 0.1214
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0196 0.0808 0.2001
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0034 0.0097 0.0104
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Echinococcus multilocularis SH2 motif 0.0399 0.1701 0.1831
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0493 0.0487
Schistosoma mansoni cathepsin D (A01 family) 0.0746 0.323 0.3226
Echinococcus granulosus zinc finger protein 0.0022 0.0042 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0032 0.0065
Echinococcus granulosus SH2 domain containing adapter protein F 0.0399 0.1701 0.1831
Onchocerca volvulus 0.0124 0.0493 0.1208
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Brugia malayi Adenylyl cyclase protein 0.0075 0.0277 0.0676
Onchocerca volvulus Putative pyridoxal kinase 0.0059 0.0205 0.0489
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0399 0.1701 0.1831
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Echinococcus multilocularis tyrosine protein kinase pr2 0.0526 0.226 0.2432
Onchocerca volvulus 0.0124 0.0493 0.1208
Onchocerca volvulus 0.0526 0.226 0.5617
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0526 0.226 0.2432
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0032 0.0034
Echinococcus multilocularis fmrfamide receptor 0.0124 0.0493 0.053
Trypanosoma brucei lipase domain protein, putative 0.0156 0.0633 0.2772
Brugia malayi RE15519p 0.0124 0.0493 0.1214
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0925 0.4016 0.4323
Brugia malayi Lipase family protein 0.0156 0.0633 0.1564
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0493 0.053
Loa Loa (eye worm) RGC/RGC protein kinase 0.0529 0.2274 0.5662
Onchocerca volvulus 0.0124 0.0493 0.1208
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0205 0.0852
Entamoeba histolytica nucleoside transporter, putative 0.0043 0.0137 0.0267
Loa Loa (eye worm) neuropeptide F receptor 0.0124 0.0493 0.1227
Schistosoma mansoni hypothetical protein 0.0062 0.0218 0.0212
Loa Loa (eye worm) TK protein kinase 0.0526 0.226 0.5627
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Toxoplasma gondii STE kinase 0.0526 0.226 0.9441
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0427 0.0994
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0151 0.0608 0.3321
Schistosoma mansoni zinc finger protein 0.0015 0.001 0.0003
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0414 0.1769 0.4363
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Schistosoma mansoni nuclear hormone receptor 0.002 0.0032 0.0026
Loa Loa (eye worm) melatonin receptor type 1A 0.0124 0.0493 0.1227
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0925 0.4016 0.4323
Echinococcus multilocularis carbonic anhydrase II 0.0469 0.201 0.2164
Toxoplasma gondii aspartyl protease 0.0198 0.0817 0.3392
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0526 0.226 0.2432
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0032 0.0065
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0144 0.0138
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0124 0.0493 0.1227
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0526 0.226 0.2432
Loa Loa (eye worm) SRC-1 0.0925 0.4016 1
Trypanosoma brucei adenosine transporter 2 0.0043 0.0137 0.0564
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Echinococcus granulosus biogenic amine 5HT receptor 0.0124 0.0493 0.053
Schistosoma mansoni neuropeptide f receptor 76f 0.0124 0.0493 0.0487
Mycobacterium tuberculosis Probable esterase LipL 0.0033 0.0091 0.0901
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0556 0.2393 1
Echinococcus granulosus serotonin transporter 0.0887 0.3849 0.4143
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0427 0.1779
Toxoplasma gondii histone lysine methyltransferase SET1 0.0109 0.0423 0.1739
Echinococcus granulosus bloom syndrome protein 0.0021 0.004 0.0043
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0526 0.226 0.9441
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0001 0.000000000067265
Loa Loa (eye worm) hypothetical protein 0.0526 0.226 0.5627
Schistosoma mansoni protein kinase 0.0526 0.226 0.2255
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus multilocularis signal transduction protein lnk realted 0.0399 0.1701 0.1831
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0816 0.3537 0.3808
Loa Loa (eye worm) hypothetical protein 0.0526 0.226 0.5627
Onchocerca volvulus 0.0151 0.0608 0.1495
Brugia malayi hypothetical protein 0.0025 0.0054 0.0119
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0032 0.0058
Echinococcus granulosus sn1 specific diacylglycerol lipase beta 0.0156 0.0633 0.0682
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0493 0.053
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0925 0.4016 0.4323
Toxoplasma gondii CAAX amino terminal protease family protein 0.0019 0.003 0.0092
Echinococcus granulosus hypothetical protein 0.0124 0.0493 0.053
Loa Loa (eye worm) Smad1 0.0015 0.0012 0.0031
Trypanosoma brucei lipase domain protein, putative 0.0156 0.0633 0.2772
Schistosoma mansoni growth hormone secretagogue receptor 0.0124 0.0493 0.0487
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0526 0.226 0.2432
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0032 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0526 0.226 0.9443
Echinococcus granulosus lamin 0.0026 0.0059 0.0063
Echinococcus granulosus neuropeptide receptor A26 0.0124 0.0493 0.053
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0124 0.0493 0.053
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.025 0.1048 0.4375
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0124 0.0493 0.053
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0414 0.1769 0.782
Echinococcus granulosus retinal guanylyl cyclase 2 0.0529 0.2274 0.2448
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0119 0.0469 0.0463
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus multilocularis dro:myosuppressin receptor 0.0124 0.0493 0.053
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0017 0.0011
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0009 0.0009
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0151 0.0608 0.1514
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Echinococcus multilocularis beta LACTamase domain containing family member 0.0033 0.0091 0.0098
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0399 0.1701 0.1696
Loa Loa (eye worm) hypothetical protein 0.0025 0.0057 0.0141
Schistosoma mansoni intermediate filament proteins 0.0026 0.0059 0.0052
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0091 0.0362
Brugia malayi Bromodomain containing protein 0.0075 0.0276 0.0672
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Loa Loa (eye worm) TYRA-2 protein 0.0124 0.0493 0.1227
Loa Loa (eye worm) hypothetical protein 0.0026 0.0059 0.0147
Schistosoma mansoni hypothetical protein 0.0799 0.3462 0.3458
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0174 0.0712 0.1773
Onchocerca volvulus 0.0124 0.0493 0.1208
Echinococcus multilocularis tyrosine protein kinase Abl 0.0925 0.4016 0.4323
Trypanosoma brucei adenosine transporter 2, putative 0.0043 0.0137 0.0564
Trypanosoma brucei purine nucleoside transporter 0.0043 0.0137 0.0564
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Echinococcus multilocularis serotonin receptor 0.0124 0.0493 0.053
Echinococcus multilocularis lamin dm0 0.0026 0.0059 0.0063
Schistosoma mansoni sodium/chloride dependent transporter 0.0887 0.3849 0.3845
Trypanosoma cruzi protein kinase, putative 0.0526 0.226 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0032 0.0034
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0124 0.0493 0.1214
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0032 0.008
Onchocerca volvulus 0.0526 0.226 0.5617
Schistosoma mansoni serine/threonine protein kinase 0.0526 0.226 0.2255
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0151 0.0608 0.1514
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Echinococcus granulosus activin receptor type 0.0526 0.226 0.2432
Loa Loa (eye worm) TK protein kinase 0.0925 0.4016 1
Echinococcus granulosus equilibrative nucleoside transporter 0.025 0.1048 0.1128
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0124 0.0493 0.1214
Echinococcus granulosus peptide allatostatin:somatostatin 0.0124 0.0493 0.053
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.025 0.1048 0.1128
Schistosoma mansoni thyroid hormone receptor 0.002 0.0032 0.0026
Toxoplasma gondii hypothetical protein 0.0151 0.0608 0.2514
Brugia malayi hypothetical protein 0.0399 0.1701 0.4228
Echinococcus granulosus tyrosine protein kinase Fyn 0.0925 0.4016 0.4323
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Brugia malayi neuropeptide F receptor 0.0124 0.0493 0.1214
Plasmodium vivax aspartyl protease, putative 0.0198 0.0817 0.339
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0091 0.0344
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0151 0.0608 0.0654
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) serotonin transporter b 0.0887 0.3849 0.9585
Trichomonas vaginalis TK family protein kinase 0.0526 0.226 0.9443
Leishmania major nucleobase transporter 0.0043 0.0137 0.0564
Mycobacterium ulcerans fructokinase, PfkB 0.0059 0.0205 0.1003
Toxoplasma gondii nucleoside transporter protein 0.0043 0.0137 0.0538
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.003 0.0198
Entamoeba histolytica hypothetical protein 0.0035 0.01 0.0175
Echinococcus multilocularis neuropeptides capa receptor 0.0124 0.0493 0.053
Loa Loa (eye worm) hypothetical protein 0.0526 0.226 0.5627
Schistosoma mansoni cathepsin D (A01 family) 0.0746 0.323 0.3226
Mycobacterium ulcerans bacterioferritin BfrB 0.0027 0.0062 0.0181
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0414 0.1769 0.1904
Schistosoma mansoni hypothetical protein 0.0062 0.0218 0.0212
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0124 0.0493 0.053
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Loa Loa (eye worm) hypothetical protein 0.0033 0.0091 0.0227
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0526 0.226 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0493 0.053
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0271 0.114 0.2839
Trypanosoma brucei unspecified product 0.0043 0.0137 0.0564
Onchocerca volvulus 0.002 0.0032 0.0058
Schistosoma mansoni neuropeptide receptor 0.0124 0.0493 0.0487
Brugia malayi MH1 domain containing protein 0.0015 0.0012 0.0016
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Brugia malayi Protein kinase domain containing protein 0.0925 0.4016 1
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0043 0.0137 0.0564
Entamoeba histolytica hypothetical protein 0.0526 0.226 0.5594
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0529 0.2274 0.5656
Echinococcus granulosus tyrosine protein kinase csk 0.0526 0.226 0.2432
Onchocerca volvulus 0.0124 0.0493 0.1208
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0399 0.1701 0.1831
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0033 0.0091 0.035
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.025 0.1048 0.2592
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0075 0.031
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0414 0.1769 0.4363
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.008
Brugia malayi phosphofructokinase 0.0109 0.0427 0.1049
Echinococcus granulosus tyrosine kinase 0.0925 0.4016 0.4323
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.025 0.1048 0.1128
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Schistosoma mansoni hypothetical protein 0.0336 0.1425 0.142
Loa Loa (eye worm) hypothetical protein 0.0068 0.0243 0.0606
Loa Loa (eye worm) neuropeptide F receptor 0.0124 0.0493 0.1227
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Trypanosoma cruzi nucleoside transporter 1, putative 0.0043 0.0137 0.0564
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0033 0.0091 0.0901
Schistosoma mansoni adenosine kinase 0.0518 0.2224 0.2219
Schistosoma mansoni zinc finger protein 0.0022 0.0042 0.0035
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0556 0.2393 0.2576
Schistosoma mansoni ferritin 0.0027 0.0062 0.0055
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0027 0.0062 0.0563
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0022 0.0016
Echinococcus granulosus TGF beta signal transducer SmadC 0.0015 0.0012 0.0013
Echinococcus multilocularis SH2 motif 0.0399 0.1701 0.1831
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0556 0.2393 0.2576
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0151 0.0608 0.2514
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Echinococcus multilocularis 6 phosphofructokinase 0.0109 0.0427 0.0459
Echinococcus granulosus protein kinase 0.0526 0.226 0.2432
Entamoeba histolytica serine/threonine kinase, putative 0.0526 0.226 0.5594
Echinococcus granulosus insulin receptor 0.0526 0.226 0.2432
Onchocerca volvulus 0.0887 0.3849 0.9584
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0414 0.1769 0.782
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0526 0.226 0.5594
Echinococcus multilocularis microtubule associated protein 2 0.2123 0.929 1
Loa Loa (eye worm) hypothetical protein 0.0319 0.135 0.3363
Loa Loa (eye worm) TK/DDR protein kinase 0.0526 0.226 0.5627
Brugia malayi G-protein coupled receptor 0.0124 0.0493 0.1214
Schistosoma mansoni opsin-like receptor 0.0124 0.0493 0.0487
Loa Loa (eye worm) MH2 domain-containing protein 0.0015 0.0012 0.0031
Brugia malayi GnHR receptor homolog 0.0124 0.0493 0.1214
Giardia lamblia Kinase 0.0526 0.226 0.9998
Loa Loa (eye worm) TK/FER protein kinase 0.0526 0.226 0.5627
Onchocerca volvulus 0.0925 0.4016 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0526 0.226 0.2432
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0075 0.0113
Loa Loa (eye worm) hypothetical protein 0.0151 0.0608 0.1514
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0887 0.3849 0.9585
Onchocerca volvulus 0.0198 0.0817 0.2018
Echinococcus multilocularis sodium and chloride dependent glycine 0.0151 0.0608 0.0654
Echinococcus multilocularis CAAX prenyl protease 2 0.0094 0.0358 0.0385
Plasmodium falciparum plasmepsin VIII, putative 0.0198 0.0817 0.3379
Leishmania major ribokinase, putative 0.0059 0.0205 0.0867
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0526 0.226 0.2432
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0032 0.008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0054 0.0134
Schistosoma mansoni carbonic anhydrase 0.0174 0.0712 0.0706
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0032 0.0034
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0032 0.0058
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0414 0.1769 1
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0526 0.226 0.9443
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Echinococcus granulosus neuropeptides capa receptor 0.0124 0.0493 0.053
Schistosoma mansoni hypothetical protein 0.0336 0.1425 0.142
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0124 0.0493 0.053
Schistosoma mansoni biogenic amine receptor 0.0124 0.0493 0.0487
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0414 0.1769 0.7392
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0399 0.1701 0.4224
Echinococcus multilocularis expressed protein 0.0027 0.0062 0.0066
Echinococcus granulosus suppressor of cytokine signaling 6 0.0399 0.1701 0.1831
Mycobacterium tuberculosis Probable hydrolase 0.0033 0.0091 0.0901
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0075 0.0278
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0124 0.0493 0.053
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0271 0.1139 0.502
Onchocerca volvulus 0.0399 0.1701 0.4224
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0427 0.042
Loa Loa (eye worm) TK protein kinase 0.0526 0.226 0.5627
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0925 0.4016 0.4012
Mycobacterium ulcerans endonuclease IV 0.0077 0.0285 0.1463
Schistosoma mansoni signal transduction protein lnk-related 0.0399 0.1701 0.1696
Echinococcus granulosus tm gpcr rhodopsin 0.0124 0.0493 0.053
Loa Loa (eye worm) hypothetical protein 0.0033 0.0091 0.0227
Brugia malayi Dopamine receptor 0.0124 0.0493 0.1214
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0124 0.0493 0.0487
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0244 0.0537
Brugia malayi Tensin 0.0399 0.1701 0.4228
Loa Loa (eye worm) TK/FER protein kinase 0.0925 0.4016 1
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0285 0.1156
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0526 0.226 0.5627
Mycobacterium ulcerans beta-lactamase 0.0033 0.0091 0.035
Treponema pallidum bacterioferrin (TpF1) 0.0027 0.0062 0.0083
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0271 0.1139 0.487
Brugia malayi hypothetical protein 0.0124 0.0493 0.1214
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0211 0.0227
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0399 0.1701 0.1831
Loa Loa (eye worm) hypothetical protein 0.0556 0.2393 0.5959
Schistosoma mansoni nck2/grb4 0.0399 0.1701 0.1696
Schistosoma mansoni protein kinase 0.0529 0.2274 0.2269
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0013 0.0007
Entamoeba histolytica hypothetical protein 0.0035 0.01 0.0175
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0493 0.053
Plasmodium vivax hypothetical protein, conserved 0.0151 0.0608 0.2512
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0399 0.1701 0.4236
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0198 0.0817 0.2035
Entamoeba histolytica CAAX prenyl protease family 0.0094 0.0358 0.0822
Trichomonas vaginalis conserved hypothetical protein 0.0526 0.226 0.9443
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0427 0.042
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0124 0.0493 0.053
Brugia malayi Dopamine receptor protein 2 0.0124 0.0493 0.1214
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0925 0.4016 0.4323
Onchocerca volvulus 0.0059 0.0205 0.0489
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0032 0.0026
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0032 0.0034
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0124 0.0493 0.1214
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0032 0.008
Echinococcus granulosus G protein coupled receptor 139 0.0124 0.0493 0.053
Loa Loa (eye worm) hypothetical protein 0.0062 0.0218 0.0543
Entamoeba histolytica hypothetical protein 0.0035 0.01 0.0175
Mycobacterium ulcerans esterase/lipase LipP 0.0033 0.0091 0.035
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0032 0.0026
Schistosoma mansoni vav2 0.0399 0.1701 0.1696
Schistosoma mansoni tyrosine kinase 0.0925 0.4016 0.4012
Leishmania major adenosine kinase-like protein 0.0059 0.0205 0.0867
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0124 0.0493 0.1208
Brugia malayi Nucleoside transporter family protein 0.025 0.1048 0.2597
Loa Loa (eye worm) TK protein kinase 0.0526 0.226 0.5627
Echinococcus granulosus NCK adaptor protein 0.0399 0.1701 0.1831
Schistosoma mansoni tensin 0.0399 0.1701 0.1696
Entamoeba histolytica nucleoside transporter, putative 0.025 0.1048 0.2552
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus multilocularis g protein coupled receptor 0.0124 0.0493 0.053
Brugia malayi MH2 domain containing protein 0.0224 0.0933 0.2311
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0094 0.0358 0.1547
Plasmodium falciparum plasmepsin IX 0.0198 0.0817 0.3379
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.025 0.1048 0.2592
Echinococcus multilocularis adenosine kinase 0.0518 0.2224 0.2393
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0075 0.0261
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0174 0.0712 0.176
Giardia lamblia Protein 21.1 0.0526 0.226 0.9998
Echinococcus multilocularis tyrosine kinase 0.0526 0.226 0.2432
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0399 0.1701 0.1831
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0817 0.0811
Schistosoma mansoni tyrosine kinase 0.0925 0.4016 0.4012
Brugia malayi Eukaryotic aspartyl protease family protein 0.0198 0.0817 0.2023
Brugia malayi SH2 domain containing protein 0.0399 0.1701 0.4228
Entamoeba histolytica serine/threonine kinase, putative 0.0526 0.226 0.5594
Brugia malayi MH2 domain containing protein 0.0015 0.0012 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0427 0.1779
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0027 0.0062 0.0563
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.0006 0.0007
Plasmodium falciparum plasmepsin V 0.0198 0.0817 0.3379
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0493 0.053
Loa Loa (eye worm) TK/FER protein kinase 0.0925 0.4016 1
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0925 0.4016 0.4323
Mycobacterium tuberculosis Ribokinase RbsK 0.0059 0.0205 0.2217
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0033 0.0091 0.0085
Brugia malayi Sex muscle abnormal protein 5 0.0399 0.1701 0.4228
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0144 0.0156
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0124 0.0493 0.0487
Schistosoma mansoni hypothetical protein 0.002 0.0032 0.0026
Trypanosoma cruzi nucleobase transporter, putative 0.0043 0.0137 0.0564
Echinococcus granulosus smad 0.0015 0.0012 0.0013
Plasmodium vivax tyrosine kinase-like protein, putative 0.0526 0.226 0.9441
Onchocerca volvulus 0.0124 0.0493 0.1208
Loa Loa (eye worm) hypothetical protein 0.0887 0.3849 0.9585
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0151 0.0608 0.0602
Trichomonas vaginalis CAMK family protein kinase 0.0526 0.226 0.9443
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0032 0.0026
Loa Loa (eye worm) protein kinase domain-containing protein 0.0526 0.226 0.5627
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Trichomonas vaginalis AGC family protein kinase 0.0526 0.226 0.9443
Echinococcus granulosus serotonin receptor 0.0124 0.0493 0.053
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0013 0.0014
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0526 0.226 0.5594
Onchocerca volvulus 0.0124 0.0493 0.1208
Echinococcus granulosus tyrosine protein kinase Fyn 0.0925 0.4016 0.4323
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0109 0.0427 0.7253
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0032 0.0065
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Trichomonas vaginalis ribokinase, putative 0.0059 0.0205 0.0852
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0399 0.1701 0.1831
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0526 0.226 0.5594
Trichomonas vaginalis D-aminoacylase, putative 0.0033 0.0091 0.0376
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Entamoeba histolytica serine/threonine kinase, putative 0.0526 0.226 0.5594
Echinococcus multilocularis neuropeptide s receptor 0.0124 0.0493 0.053
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0022 0.0016
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0285 0.1141
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0271 0.114 0.1227
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0526 0.226 0.5627
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0414 0.1769 0.782
Trypanosoma cruzi hypothetical protein, conserved 0.0156 0.0633 0.2772
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Echinococcus multilocularis sn1 specific diacylglycerol lipase beta 0.0156 0.0633 0.0682
Toxoplasma gondii kinase, pfkB family protein 0.0518 0.2224 0.9289
Echinococcus multilocularis serotonin receptor 0.0124 0.0493 0.053
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Echinococcus multilocularis tumor protein p63 0.038 0.1616 0.1739
Schistosoma mansoni protein kinase 0.0526 0.226 0.2255
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Trypanosoma brucei adenosine transporter 2, putative 0.0043 0.0137 0.0564
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0925 0.4016 0.4323
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0493 0.053
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0151 0.0608 0.2514
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0013 0.002
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0271 0.0292
Loa Loa (eye worm) hypothetical protein 0.0526 0.226 0.5627
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0529 0.2274 0.5656
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0124 0.0493 0.1227
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0013 0.0016
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0526 0.226 1
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0399 0.1701 0.1831
Brugia malayi AKH receptor 0.0124 0.0493 0.1214
Schistosoma mansoni biogenic amine receptor 0.0124 0.0493 0.0487
Trichomonas vaginalis penicillin-binding protein, putative 0.0033 0.0091 0.0376
Leishmania major hypothetical protein, conserved 0.0025 0.0054 0.0196
Loa Loa (eye worm) norepinephrine transporter 0.0887 0.3849 0.9585
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.0059 0.0205 0.022
Schistosoma mansoni ferritin light chain 0.0027 0.0062 0.0055
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0526 0.226 0.5627
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0032 0.008
Echinococcus granulosus carbonic anhydrase II 0.0469 0.201 0.2164
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0493 0.0487
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0001 0.000000000067265
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0925 0.4016 0.4323
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Schistosoma mansoni sodium/chloride dependent transporter 0.0151 0.0608 0.0602
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0151 0.0608 0.0654
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0414 0.1769 0.782
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Plasmodium vivax amine transporter, putative 0.0151 0.0608 0.2512
Onchocerca volvulus 0.0526 0.226 0.5617
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0062 0.0218 0.0235
Brugia malayi Protein kinase domain containing protein 0.0925 0.4016 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0032 0.0034
Echinococcus granulosus methyl CpG binding domain protein 2 0.0016 0.0017 0.0018
Onchocerca volvulus 0.0151 0.0608 0.1495
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0414 0.1769 0.7392
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0124 0.0493 0.1214
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0526 0.226 0.2432
Brugia malayi Tyrosine-protein kinase abl-1 0.0925 0.4016 1
Schistosoma mansoni opsin-like receptor 0.0124 0.0493 0.0487
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0077 0.0285 0.4628
Loa Loa (eye worm) serine/threonine protein kinase 0.0526 0.226 0.5627
Echinococcus multilocularis insulin receptor 0.0526 0.226 0.2432
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Schistosoma mansoni sodium/chloride dependent transporter 0.0151 0.0608 0.0602
Schistosoma mansoni thyroid hormone receptor 0.002 0.0032 0.0026
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0124 0.0493 0.0487
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0399 0.1701 0.1831
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Treponema pallidum sodium- and chloride- dependent transporter 0.0887 0.3849 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0124 0.0493 0.0487
Echinococcus granulosus FTZ F1 alpha 0.002 0.0032 0.0034
Schistosoma mansoni hypothetical protein 0.0399 0.1701 0.1696
Entamoeba histolytica serine/threonine kinase, putative 0.0526 0.226 0.5594
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Loa Loa (eye worm) hypothetical protein 0.0526 0.226 0.5627
Schistosoma mansoni tensin 0.0399 0.1701 0.1696
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0151 0.0608 0.0602
Echinococcus multilocularis orexin receptor type 2 0.0124 0.0493 0.053
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0817 0.0811
Trichomonas vaginalis protein tyrosine kinase, putative 0.0526 0.226 0.9443
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0062 0.0218 0.0235
Plasmodium falciparum tyrosine kinase-like protein 0.0526 0.226 0.944
Schistosoma mansoni smad1 5 8 and 0.0015 0.0012 0.0006
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0925 0.4016 0.4323
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0022 0.0024
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0399 0.1701 0.1696
Schistosoma mansoni suppressor of cytokine signaling 0.0399 0.1701 0.1696
Entamoeba histolytica serine/threonine kinase, putative 0.0526 0.226 0.5594
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0013 0.002
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Brugia malayi hypothetical protein 0.0043 0.0137 0.0325
Entamoeba histolytica hypothetical protein 0.0035 0.01 0.0175
Brugia malayi Tyrosine-protein kinase PR2 0.0526 0.226 0.562
Loa Loa (eye worm) TK/FER protein kinase 0.0526 0.226 0.5627
Plasmodium falciparum protein kinase, putative 0.0526 0.226 0.944
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0032 0.0065
Schistosoma mansoni amine GPCR 0.0124 0.0493 0.0487
Schistosoma mansoni growth factor receptor-bound protein 0.0399 0.1701 0.1696
Brugia malayi neuropeptide F receptor 0.0124 0.0493 0.1214
Trichomonas vaginalis lipase containing protein, putative 0.0156 0.0633 0.2643
Onchocerca volvulus 0.0124 0.0493 0.1208
Loa Loa (eye worm) hypothetical protein 0.0526 0.226 0.5627
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0399 0.1701 0.1831
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0032 0.0034
Loa Loa (eye worm) TK/FER protein kinase 0.0925 0.4016 1
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Schistosoma mansoni cpg binding protein 0.0056 0.0192 0.0186
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0399 0.1701 0.1831
Loa Loa (eye worm) hypothetical protein 0.0526 0.226 0.5627
Entamoeba histolytica receptor protein kinase, putative 0.0526 0.226 0.5594
Schistosoma mansoni ribokinase 0.0059 0.0205 0.0198
Echinococcus granulosus tm gpcr rhodopsin 0.1374 0.5996 0.6453
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.01 0.0094
Schistosoma mansoni neuropeptide receptor 0.0124 0.0493 0.0487
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0124 0.0493 0.1227
Onchocerca volvulus 0.0124 0.0493 0.1208
Brugia malayi hypothetical protein 0.0124 0.0493 0.1214
Loa Loa (eye worm) hypothetical protein 0.0033 0.0091 0.0227
Leishmania major adenosine kinase-like protein 0.0059 0.0205 0.0867
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0009 0.0009
Trypanosoma brucei adenosine transporter 2, putative 0.0043 0.0137 0.0564
Onchocerca volvulus 0.0056 0.0192 0.0457
Loa Loa (eye worm) lipase 0.0156 0.0633 0.1577
Echinococcus granulosus signal transduction protein lnk realted 0.0399 0.1701 0.1831
Loa Loa (eye worm) hypothetical protein 0.0526 0.226 0.5627
Leishmania major nucleoside transporter 1, putative 0.0043 0.0137 0.0564
Trichomonas vaginalis conserved hypothetical protein 0.0526 0.226 0.9443
Onchocerca volvulus 0.0124 0.0493 0.1208
Trypanosoma brucei carbonic anhydrase-like protein 0.0469 0.201 0.8891
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0124 0.0493 0.0487
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0043 0.0137 0.0566
Schistosoma mansoni ferritin 0.0027 0.0062 0.0055
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Loa Loa (eye worm) TK protein kinase 0.0526 0.226 0.5627
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0054 0.019
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0128 0.051 0.2225
Echinococcus granulosus Ankyrin 0.0015 0.0009 0.001
Echinococcus granulosus tyrosine protein kinase pr2 0.0526 0.226 0.2432
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0151 0.0608 0.0602
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Echinococcus multilocularis GPCR, family 2 0.0062 0.0218 0.0235
Onchocerca volvulus 0.0033 0.0091 0.0205
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0032 0.0034
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0151 0.0608 0.0654
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0032 0.0065
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Echinococcus multilocularis natriuretic peptide receptor 1 0.0526 0.226 0.2432
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0526 0.226 0.2255
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0207 0.0856 0.0922
Onchocerca volvulus 0.0156 0.0633 0.1558
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0032 0.0065
Schistosoma mansoni adenoreceptor 0.0124 0.0493 0.0487
Echinococcus multilocularis cpg binding protein 0.0061 0.0214 0.0231
Trypanosoma cruzi nucleobase transporter, putative 0.0043 0.0137 0.0564
Onchocerca volvulus 0.0459 0.1964 0.4879
Echinococcus multilocularis NCK adaptor protein 0.0399 0.1701 0.1831
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Loa Loa (eye worm) hypothetical protein 0.0151 0.0608 0.1514
Echinococcus multilocularis tyrosine protein kinase csk 0.0526 0.226 0.2432
Loa Loa (eye worm) TK/ABL protein kinase 0.0925 0.4016 1
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0526 0.226 0.5627
Onchocerca volvulus 0.0124 0.0493 0.1208
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0128 0.051 0.2225
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0174 0.0712 0.176
Entamoeba histolytica hypothetical protein, conserved 0.0526 0.226 0.5594
Onchocerca volvulus 0.0399 0.1701 0.4224
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0526 0.226 0.2432
Schistosoma mansoni netrin receptor unc5 0.0014 0.0009 0.0002
Schistosoma mansoni protein kinase 0.0526 0.226 0.2255
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0414 0.1769 0.1764
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0032 0.0065
Echinococcus granulosus SH2 motif 0.0399 0.1701 0.1831
Brugia malayi Melatonin receptor type 1A 0.0124 0.0493 0.1214
Trichomonas vaginalis STE family protein kinase 0.0526 0.226 0.9443
Echinococcus multilocularis neuropeptide Y receptor 0.0124 0.0493 0.053
Loa Loa (eye worm) RGC/RGC protein kinase 0.0529 0.2274 0.5662
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0001 0.000000000067265
Plasmodium vivax aspartyl proteinase, putative 0.0556 0.2393 1
Plasmodium vivax plasmepsin V, putative 0.0198 0.0817 0.339
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0009 0.0003
Toxoplasma gondii hypothetical protein 0.0019 0.003 0.0092
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Loa Loa (eye worm) hypothetical protein 0.0399 0.1701 0.4236
Echinococcus multilocularis carbonic anhydrase 0.0174 0.0712 0.0766
Echinococcus granulosus fmrfamide receptor 0.0124 0.0493 0.053
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0244 0.1043
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.01 0.0108
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0526 0.226 0.2432
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0124 0.0493 0.0487
Loa Loa (eye worm) TK/CSK protein kinase 0.0526 0.226 0.5627
Brugia malayi ephrin receptor 1 precursor 0.0526 0.226 0.562
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0526 0.226 0.9443
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0493 0.053
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0469 0.201 0.8891
Trichomonas vaginalis conserved hypothetical protein 0.0526 0.226 0.9443
Schistosoma mansoni cpg binding protein 0.0061 0.0214 0.0208
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0043 0.0137 0.0566
Loa Loa (eye worm) TK/RYK protein kinase 0.0526 0.226 0.5627
Echinococcus multilocularis tyrosine protein kinase csk 0.0526 0.226 0.2432
Echinococcus multilocularis G protein coupled receptor 139 0.0124 0.0493 0.053
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0032 0.0065
Echinococcus multilocularis SH2 domain containing protein 7 0.0399 0.1701 0.1831
Brugia malayi putative neuropeptide receptor NPR1 0.0124 0.0493 0.1214
Toxoplasma gondii hypothetical protein 0.0019 0.003 0.0092
Trypanosoma brucei adenosine transporter 2 0.0043 0.0137 0.0564
Schistosoma mansoni suppressor of cytokine signaling 0.0399 0.1701 0.1696
Mycobacterium tuberculosis Conserved protein 0.0033 0.0091 0.0901
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0032 0.008
Mycobacterium tuberculosis Probable lipase LipD 0.0033 0.0091 0.0901
Trypanosoma cruzi nucleoside transporter-like, putative 0.0043 0.0137 0.0564
Entamoeba histolytica fructokinase, putative 0.0059 0.0205 0.0438
Schistosoma mansoni protein kinase 0.0526 0.226 0.2255
Brugia malayi hypothetical protein 0.0124 0.0493 0.1214
Trypanosoma brucei CAAX amino terminal protease, putative 0.0094 0.0358 0.1547
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0043 0.0137 0.0564
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0032 0.0065
Brugia malayi Immunoglobulin I-set domain containing protein 0.0526 0.226 0.562
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0271 0.114 0.1227
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0427 0.1062
Echinococcus granulosus intermediate filament protein 0.0026 0.0059 0.0063
Onchocerca volvulus 0.0399 0.1701 0.4224
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0075 0.0281
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0062 0.0218 0.0235
Schistosoma mansoni hypothetical protein 0.0035 0.01 0.0094
Schistosoma mansoni cpg binding protein 0.0061 0.0214 0.0208
Schistosoma mansoni alpha-1 adrenergic receptor 0.0124 0.0493 0.0487
Leishmania major putative PfkB family sugar kinase 0.0059 0.0205 0.0867
Echinococcus multilocularis Smad4 0.0015 0.0012 0.0013
Brugia malayi hypothetical protein 0.0526 0.226 0.562
Schistosoma mansoni myosin xvIII 0.0124 0.0493 0.0487
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0043 0.0137 0.0564
Echinococcus multilocularis neuropeptide receptor 0.0124 0.0493 0.053
Echinococcus granulosus SH2 domain containing protein 7 0.0399 0.1701 0.1831
Loa Loa (eye worm) hypothetical protein 0.0151 0.0608 0.1514
Brugia malayi ORL1-like opioid receptor 0.0124 0.0493 0.1214
Echinococcus granulosus biogenic amine 5HT receptor 0.0124 0.0493 0.053
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0399 0.1701 0.4236
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0032 0.008
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0013 0.0016
Brugia malayi bone morphogenetic protein type 1 receptor 0.0526 0.226 0.562
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Echinococcus granulosus g-protein coupled receptor 0.0124 0.0493 0.053
Echinococcus granulosus mothers against decapentaplegic 5 0.0015 0.0012 0.0013
Schistosoma mansoni serine/threonine RGC 0.0529 0.2274 0.2269
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0244 0.1043
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Echinococcus granulosus tyrosine kinase 0.0925 0.4016 0.4323
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Onchocerca volvulus 0.0925 0.4016 1
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Schistosoma mansoni opsin-like receptor 0.0124 0.0493 0.0487
Trypanosoma brucei protein kinase, putative 0.0526 0.226 1
Toxoplasma gondii hypothetical protein 0.0151 0.0608 0.2514
Brugia malayi hypothetical protein 0.0151 0.0608 0.1501
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0271 0.114 0.4763
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0032 0.0026
Onchocerca volvulus 0.0399 0.1701 0.4224
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Giardia lamblia Hypothetical protein 0.0094 0.0358 0.1293
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0556 0.2393 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0075 0.031
Loa Loa (eye worm) solute carrier family 6 member 4 0.0887 0.3849 0.9585
Echinococcus granulosus neuropeptide receptor 0.0124 0.0493 0.053
Echinococcus multilocularis allatostatin A receptor 0.0124 0.0493 0.053
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0526 0.226 0.2432
Loa Loa (eye worm) phosphofructokinase 0.0109 0.0427 0.1062
Trypanosoma brucei adenosine transporter 2, putative 0.0043 0.0137 0.0564
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Schistosoma mansoni carbonic anhydrase-related 0.0174 0.0712 0.0706
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0526 0.226 0.9441
Plasmodium falciparum plasmepsin X 0.0198 0.0817 0.3379
Plasmodium falciparum protein kinase, putative 0.0526 0.226 0.944
Brugia malayi beta-lactamase 0.0033 0.0091 0.0212
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0075 0.0261
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0151 0.0608 0.0602
Echinococcus granulosus tyrosine protein kinase Src42A 0.0925 0.4016 0.4323
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0414 0.1769 0.782
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0091 0.0362
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0124 0.0493 0.1227
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0109 0.0427 0.4784
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0493 0.053
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0028 0.0063
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0526 0.226 0.5627
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0493 0.0487
Brugia malayi G-protein coupled receptor 0.0124 0.0493 0.1214
Brugia malayi nuclear hormone receptor 0.002 0.0032 0.0065
Echinococcus granulosus sodium and chloride dependent glycine 0.0151 0.0608 0.0654
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0124 0.0493 0.0487
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0016 0.0017 0.0018
Loa Loa (eye worm) hypothetical protein 0.0075 0.0277 0.069
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0493 0.0487
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0128 0.051 0.2225
Loa Loa (eye worm) hypothetical protein 0.0043 0.0137 0.034
Echinococcus granulosus carbonic anhydrase 0.0174 0.0712 0.0766
Schistosoma mansoni amine GPCR 0.0124 0.0493 0.0487
Loa Loa (eye worm) hypothetical protein 0.0174 0.0712 0.1773
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0151 0.0608 0.0654
Echinococcus granulosus rhodopsin orphan GPCR 0.0124 0.0493 0.053
Plasmodium falciparum plasmepsin IV 0.0556 0.2393 1
Echinococcus multilocularis smad 0.0015 0.0012 0.0013
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0529 0.2274 0.5653
Schistosoma mansoni cellular tumor antigen P53 0.0056 0.019 0.0183
Entamoeba histolytica tyrosine kinase, putative 0.0526 0.226 0.5594
Echinococcus granulosus somatostatin receptor 0.0124 0.0493 0.053
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0128 0.051 0.1257
Schistosoma mansoni hypothetical protein 0.0062 0.0218 0.0212
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0032 0.0026
Trypanosoma cruzi protein kinase, putative 0.0526 0.226 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0124 0.0493 0.053
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0032 0.0065
Leishmania major tagatose-6-phosphate kinase-like protein 0.0059 0.0205 0.0867
Brugia malayi Variant SH3 domain containing protein 0.0399 0.1701 0.4228
Echinococcus multilocularis protein kinase 0.0526 0.226 0.2432
Brugia malayi protein-tyrosine kinase 0.0925 0.4016 1
Entamoeba histolytica ankyrin repeat protein 0.0526 0.226 0.5594
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0027 0.0062 0.0506
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Mycobacterium ulcerans carbohydrate kinase CbhK 0.0059 0.0205 0.1003
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0526 0.226 0.2432
Loa Loa (eye worm) hypothetical protein 0.0198 0.0817 0.2035
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0124 0.0493 0.0487
Schistosoma mansoni hypothetical protein 0.0124 0.0493 0.0487
Plasmodium vivax aspartyl protease, putative 0.0198 0.0817 0.339
Trichomonas vaginalis ribokinase, putative 0.0059 0.0205 0.0852
Loa Loa (eye worm) TK/FER protein kinase 0.0925 0.4016 1
Loa Loa (eye worm) TK/FER protein kinase 0.0925 0.4016 1
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0209 0.0865 0.2136
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Onchocerca volvulus 0.0925 0.4016 1
Brugia malayi beta-lactamase family protein 0.0033 0.0091 0.0212
Loa Loa (eye worm) hypothetical protein 0.0174 0.0712 0.1773
Echinococcus multilocularis neuropeptides capa receptor 0.0124 0.0493 0.053
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0427 0.1853
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0151 0.0608 0.1501
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0054 0.0048
Toxoplasma gondii endonuclease IV APN 0.0077 0.0285 0.1159
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Schistosoma mansoni growth factor receptor-bound protein 0.0399 0.1701 0.1696
Onchocerca volvulus Neuropeptide F receptor homolog 0.0124 0.0493 0.1208
Brugia malayi hypothetical protein 0.0059 0.0205 0.0496
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0399 0.1701 0.1831
Schistosoma mansoni adenosine kinase 0.0518 0.2224 0.2219
Entamoeba histolytica hypothetical protein 0.0526 0.226 0.5594
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0032 0.0034
Schistosoma mansoni smad 0.0015 0.0012 0.0006
Loa Loa (eye worm) beta-lactamase 0.0033 0.0091 0.0227
Loa Loa (eye worm) hypothetical protein 0.0059 0.0205 0.051
Toxoplasma gondii aspartyl protease ASP1 0.0556 0.2393 1
Trichomonas vaginalis conserved hypothetical protein 0.0526 0.226 0.9443
Echinococcus granulosus orexin receptor type 2 0.0124 0.0493 0.053
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0414 0.1769 0.7379
Echinococcus multilocularis tyrosine protein kinase 0.0526 0.226 0.2432
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0124 0.0493 0.0487
Schistosoma mansoni amine GPCR 0.0124 0.0493 0.0487
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Schistosoma mansoni histamine h1 receptor 0.0124 0.0493 0.0487
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0529 0.2274 0.2448
Echinococcus multilocularis rhodopsin orphan GPCR 0.0124 0.0493 0.053
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0526 0.226 0.5594
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0817 0.0811
Echinococcus granulosus equilibrative nucleoside transporter 3 0.025 0.1048 0.1128
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0013 0.0016
Toxoplasma gondii kinase, pfkB family protein 0.0059 0.0205 0.0824
Entamoeba histolytica hypothetical protein 0.0526 0.226 0.5594
Schistosoma mansoni ferritin 0.0027 0.0062 0.0055
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0032 0.0065
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Brugia malayi Calcitonin receptor-like protein seb-1 0.0196 0.0808 0.2001
Echinococcus multilocularis N chimaerin 0.0399 0.1701 0.1831
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0144 0.036
Entamoeba histolytica hypothetical protein 0.0526 0.226 0.5594
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0526 0.226 0.562
Plasmodium vivax tyrosine kinase-like protein, putative 0.0526 0.226 0.9441
Loa Loa (eye worm) TK/EGFR protein kinase 0.0526 0.226 0.5627
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0143 0.0574 0.2396
Loa Loa (eye worm) hypothetical protein 0.0134 0.0535 0.1333
Mycobacterium leprae conserved hypothetical protein 0.0033 0.0091 0.1048
Brugia malayi hypothetical protein 0.0124 0.0493 0.1214
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Brugia malayi Pepsin A precursor 0.0198 0.0817 0.2023
Plasmodium vivax aspartyl protease, putative 0.0198 0.0817 0.339
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0022
Entamoeba histolytica ribokinase, putative 0.0059 0.0205 0.0438
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0124 0.0493 0.053
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0124 0.0493 0.053
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Echinococcus multilocularis c src tyrosine kinase 0.0925 0.4016 0.4323
Onchocerca volvulus 0.0526 0.226 0.5617
Loa Loa (eye worm) MH2 domain-containing protein 0.0224 0.0933 0.2322
Plasmodium falciparum amino acid transporter, putative 0.0151 0.0608 0.2499
Entamoeba histolytica tyrosin kinase, putative 0.0526 0.226 0.5594
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Schistosoma mansoni smad1 5 8 and 0.0015 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0244 0.0594
Schistosoma mansoni hypothetical protein 0.0134 0.0535 0.0529
Echinococcus granulosus geminin 0.0336 0.1425 0.1534
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0356 0.1512 0.3765
Loa Loa (eye worm) hypothetical protein 0.0077 0.0285 0.0709
Schistosoma mansoni ephrin receptor 0.0526 0.226 0.2255
Schistosoma mansoni bromodomain containing protein 0.0064 0.0226 0.022
Loa Loa (eye worm) carbonic anhydrase 3 0.0469 0.201 0.5006
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.0059 0.0205 0.0438
Onchocerca volvulus 0.0056 0.019 0.0451
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Trichomonas vaginalis conserved hypothetical protein 0.0526 0.226 0.9443
Onchocerca volvulus 0.0124 0.0493 0.1208
Echinococcus granulosus epidermal growth factor receptor 0.0526 0.226 0.2432
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0244 0.1043
Brugia malayi 6-phosphofructokinase 0.0109 0.0427 0.1049
Echinococcus granulosus CAAX prenyl protease 2 0.0094 0.0358 0.0385
Schistosoma mansoni hypothetical protein 0.0124 0.0493 0.0487
Loa Loa (eye worm) SH2 domain-containing protein 0.0399 0.1701 0.4236
Entamoeba histolytica kinase, PfkB family 0.0059 0.0205 0.0438
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0529 0.2274 0.2448
Trichomonas vaginalis TKL family protein kinase 0.0526 0.226 0.9443
Loa Loa (eye worm) hypothetical protein 0.0151 0.0608 0.1514
Schistosoma mansoni biogenic amine receptor 0.0124 0.0493 0.0487
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0124 0.0493 0.0487
Schistosoma mansoni ferritin light chain 0.0027 0.0062 0.0055
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0817 0.0811
Schistosoma mansoni Smad4 0.0015 0.0012 0.0006
Trypanosoma brucei adenosine kinase, putative 0.0518 0.2224 0.9839
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0271 0.1139 0.502
Brugia malayi Uncoordinated protein 44 0.0014 0.0009 0.0007
Brugia malayi hypothetical protein 0.0124 0.0493 0.1214
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0094 0.0358 0.1547
Brugia malayi ecdysteroid receptor 0.002 0.0032 0.0065
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0032 0.008
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0043 0.0137 0.0566
Schistosoma mansoni carbonic anhydrase-related 0.0174 0.0712 0.0706
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0032 0.0034
Loa Loa (eye worm) adenylyl cyclase 3 0.0075 0.0277 0.069
Entamoeba histolytica serine/threonine kinase, putative 0.0526 0.226 0.5594
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0414 0.1769 0.7392
Loa Loa (eye worm) hypothetical protein 0.0196 0.0808 0.2013
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Loa Loa (eye worm) hypothetical protein 0.0124 0.0493 0.1227
Loa Loa (eye worm) TK/FER protein kinase 0.0925 0.4016 1
Brugia malayi hypothetical protein 0.0122 0.0484 0.1193
Brugia malayi isocitrate dehydrogenase 0.0015 0.0013 0.0018
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0414 0.1769 1
Schistosoma mansoni adapter molecule crk 0.0399 0.1701 0.1696
Onchocerca volvulus 0.0526 0.226 0.5617
Schistosoma mansoni neuropeptide F-like receptor 0.0124 0.0493 0.0487
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0414 0.1769 0.782
Echinococcus granulosus epidermal growth factor receptor 0.0526 0.226 0.2432
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0032 0.008
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0526 0.226 0.2432
Entamoeba histolytica protein kinase, putative 0.0399 0.1701 0.4192
Echinococcus granulosus cpg binding protein 0.0061 0.0214 0.0231
Echinococcus granulosus kinase suppressor of Ras 1 0.0526 0.226 0.2432
Echinococcus granulosus alpha 1A adrenergic receptor 0.0124 0.0493 0.053
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.025 0.1048 0.4375
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0094 0.0358 0.0352
Echinococcus granulosus adenosine kinase 0.0518 0.2224 0.2393
Loa Loa (eye worm) TK/FER protein kinase 0.0526 0.226 0.5627
Onchocerca volvulus Ribokinase homolog 0.0059 0.0205 0.0489
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0043 0.0137 0.0564
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1374 0.5996 0.6453
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0414 0.1769 0.7385
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0925 0.4016 1
Loa Loa (eye worm) hypothetical protein 0.0198 0.0817 0.2035
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0526 0.226 0.5594
Schistosoma mansoni tyrosine kinase 0.0526 0.226 0.2255
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0144 0.0156
Echinococcus granulosus 7TM GPCR rhodopsin 0.0124 0.0493 0.053
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Echinococcus multilocularis epidermal growth factor receptor 0.0526 0.226 0.2432
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0271 0.114 0.4763
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0118 0.0127
Plasmodium falciparum plasmepsin VII 0.0198 0.0817 0.3379
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0075 0.031
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0212 0.0878 1
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.0059 0.0205 0.0438
Trypanosoma brucei purine nucleoside transporter 0.0043 0.0137 0.0564
Onchocerca volvulus 0.0124 0.0493 0.1208
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.0059 0.0205 0.2217
Entamoeba histolytica protein kinase, putative 0.0526 0.226 0.5594
Loa Loa (eye worm) hypothetical protein 0.0033 0.0091 0.0227
Schistosoma mansoni neuropeptide receptor 0.0124 0.0493 0.0487
Brugia malayi RhoGAP domain containing protein 0.0399 0.1701 0.4228
Leishmania major hypothetical protein, conserved 0.0526 0.226 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0151 0.0608 0.1501
Schistosoma mansoni serine/threonine protein kinase 0.0526 0.226 0.2255
Echinococcus multilocularis tyrosine protein kinase csk 0.0526 0.226 0.2432
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0124 0.0493 0.053
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0399 0.1701 0.1696
Brugia malayi Protein kinase domain containing protein 0.0526 0.226 0.562
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0925 0.4016 0.4323
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0526 0.226 0.9443
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0032 0.0065
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0174 0.0712 0.176
Echinococcus multilocularis lamin 0.0026 0.0059 0.0063
Entamoeba histolytica protein kinase domain containing protein 0.0526 0.226 0.5594
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0526 0.226 0.2432
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0075 0.031

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 5.58 nM Inhibition of binding of [3H]-naloxone to Opioid receptor mu 1 in the rat brain homogenate ChEMBL. 6296388
IC50 (functional) = 7.09 nM Inhibitory potency against Opioid receptor mu 1 in the guinea pig ileum assay ChEMBL. 6296388
IC50 (functional) = 33.8 nM Inhibitory potency against Opioid receptor delta 1 in the mouse vas deferens assay ChEMBL. 6296388
IC50 (binding) = 98.3 nM Inhibition of binding of [3H][D-Ala2,D-Leu5]enkephalin to Opioid receptor delta 1 in the rat brain homogenate ChEMBL. 6296388
Ke (functional) = 0.606 nM Inhibition of naloxone activity in mouse vas deferens assay for Opioid receptor delta 1 ChEMBL. 6296388
Ke (functional) = 0.875 nM Senstivity to naloxone against Opioid receptor mu 1 in the guinea pig ileum assay ChEMBL. 6296388
Ki (binding) = 3.1 nM Inhibition of binding of [3H]-naloxone to Opioid receptor mu 1 in the rat brain homogenate ChEMBL. 6296388
Ki (binding) = 44.7 nM Inhibition of binding of [3H][D-Ala2,D-Leu5]enkephalin to Opioid receptor delta 1 in the rat brain homogenate ChEMBL. 6296388
Ratio (functional) = 4.77 IC50 ratio measured as inhibitory potencies in mouse vas deferens and guinea pig ileum assays ChEMBL. 6296388
Ratio (binding) = 14.4 Ki ratio measured as inhibitory effect against delta and mu opioid receptors ChEMBL. 6296388

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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