Detailed information for compound 44806

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 400.126 | Formula: C10H10O13P2------
  • H donors: 1 H acceptors: 11 LogP: -3.22 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: O[C@@H]1[C@@H](C=C(C[C@@H]1O[C@](P(=O)([O-])[O-])(C(=O)[O-])C)C(=O)[O-])OP(=O)([O-])[O-]
  • InChi: 1S/C10H16O13P2/c1-10(9(14)15,24(16,17)18)22-5-2-4(8(12)13)3-6(7(5)11)23-25(19,20)21/h3,5-7,11H,2H2,1H3,(H,12,13)(H,14,15)(H2,16,17,18)(H2,19,20,21)/p-6/t5-,6-,7+,10+/m1/s1
  • InChiKey: HUOJJMMXOWLGJU-JQCUSGDOSA-H  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi Cytochrome P450 family protein 0.002 0.0011 0.0002
Echinococcus granulosus tumor protein p63 0.037 0.2998 0.3022
Brugia malayi Ets-domain containing protein 0.0075 0.0483 0.0493
Echinococcus multilocularis traf and tnf receptor associated protein 0.0032 0.0114 0.0115
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0114 0.0886
Loa Loa (eye worm) hypothetical protein 0.0051 0.0278 0.0283
Brugia malayi Fli-1 protein 0.0228 0.1784 0.1846
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0075 0.0483 0.0496
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0079 0.0073
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0056 0.0057
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0157 0.1181 1
Echinococcus multilocularis SAM and MBT domain containing protein 0.0191 0.1471 0.1482
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0032 0.0114 0.0783
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0704 0.1616
Trypanosoma brucei isocitrate dehydrogenase, putative 0.005 0.0267 0.2193
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0003
Echinococcus multilocularis snurportin 1 0.0316 0.2537 0.2557
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0053 0.0293 0.0299
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.005 0.0267 0.2062
Schistosoma mansoni hypothetical protein 0.0127 0.093 0.093
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0278 0.2156
Echinococcus granulosus lamin 0.0028 0.0079 0.008
Toxoplasma gondii isocitrate dehydrogenase 0.005 0.0267 0.083
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0402 0.3276 0.3395
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0478 0.399
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0478 0.399
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.0293 0.0296
Loa Loa (eye worm) hypothetical protein 0.0032 0.0114 0.0113
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0157 0.1181 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0035 0.0141 0.0141
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0783 0.6523 0.6576
Brugia malayi Importin beta-1 subunit 0.003 0.0097 0.0091
Schistosoma mansoni hypothetical protein 0.0031 0.011 0.011
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0032 0.0114 0.0886
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0024 0.0019
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0079
Brugia malayi hypothetical protein 0.0025 0.0056 0.0049
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0157 0.1181 0.1222
Onchocerca volvulus 0.0032 0.0114 0.0139
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0032 0.0114 0.0113
Plasmodium falciparum phd finger protein, putative 0.0031 0.011 0.0699
Mycobacterium tuberculosis Conserved protein 0.0074 0.0478 0.1174
Echinococcus multilocularis importin subunit beta 1 0.003 0.0097 0.0097
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0101 0.0704 0.5923
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0306 0.0306
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0032 0.0114 0.0295
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0052
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0478 0.0478
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0052
Brugia malayi nuclear receptor NHR-88 0.0053 0.0293 0.0296
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0032 0.0114 0.0783
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0032 0.0114 0.0295
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0056 0.0057
Echinococcus multilocularis mitogen activated protein kinase 3 0.0101 0.0704 0.071
Mycobacterium ulcerans beta-lactamase 0.0074 0.0478 0.1623
Schistosoma mansoni hypothetical protein 0.0127 0.093 0.093
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0133 0.0979 0.247
Schistosoma mansoni hypothetical protein 0.0316 0.2537 0.2537
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0056 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0079
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0032 0.0114 0.0886
Entamoeba histolytica hypothetical protein 0.0035 0.0141 0.1016
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0032 0.0114 0.0783
Schistosoma mansoni survival motor neuron protein 0.0149 0.1113 0.1113
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0024 0.0045
Mycobacterium ulcerans lipase LipD 0.0074 0.0478 0.1623
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0114 0.011
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0081 0.0081
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0032 0.0114 0.0732
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0114 0.011
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0032 0.0114 0.0215
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0127 0.0924 0.0932
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0081 0.0082
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0056 0.0052
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0083 0.0553 0.0558
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.003 0.003
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0166 0.0168
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0052
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0032 0.0114 0.0783
Brugia malayi intermediate filament protein 0.0028 0.0079 0.0073
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0024 0.0024
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0032 0.0114 0.0783
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0231 0.1812 0.1827
Echinococcus granulosus neutral sphingomyelinase 0.0032 0.0114 0.0115
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0052
Onchocerca volvulus 0.0028 0.0079 0.0055
Echinococcus multilocularis survival motor neuron protein 1 0.0729 0.6062 0.6111
Brugia malayi Isocitrate dehydrogenase 0.005 0.0267 0.0269
Brugia malayi Calcitonin receptor-like protein seb-1 0.0402 0.3276 0.3395
Brugia malayi steroid hormone receptor 0.0053 0.0293 0.0296
Schistosoma mansoni smad 0.0035 0.0141 0.0141
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0101 0.0704 0.5923
Brugia malayi hypothetical protein 0.0051 0.0278 0.028
Loa Loa (eye worm) hypothetical protein 0.0032 0.0114 0.0113
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0079 0.0076
Schistosoma mansoni aldehyde dehydrogenase 0.0118 0.0849 0.0849
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0056 0.0057
Trichomonas vaginalis ap endonuclease, putative 0.0157 0.1181 0.2751
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0056 0.0057
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0478 0.1079
Schistosoma mansoni hypothetical protein 0.0149 0.1113 0.1113
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0032 0.0114 0.0115
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0032 0.0114 0.0215
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0911 0.0911
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0102 0.0716 0.0722
Mycobacterium tuberculosis Probable reductase 0.0109 0.0777 0.1948
Echinococcus granulosus ecdysone induced protein 78C 0.0053 0.0293 0.0296
Echinococcus multilocularis smad 0.0035 0.0141 0.0142
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0056 0.0056
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0114 0.0886
Brugia malayi beta-lactamase family protein 0.0074 0.0478 0.0488
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0149 0.1113 0.1147
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.005 0.0267 0.2193
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1148 0.9631 1
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.011 0.0111
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0053 0.0293 0.0296
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0191 0.1471 0.1471
Echinococcus multilocularis polycomb protein SCMH1 0.0191 0.1471 0.1482
Entamoeba histolytica Ran family GTPase 0.0022 0.003 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0053 0.0293 0.0296
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0411 0.0411
Schistosoma mansoni zinc finger protein 0.0021 0.0023 0.0023
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.005 0.0267 0.063
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0024 0.0024
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0049 0.0327
Schistosoma mansoni hypothetical protein 0.0127 0.0924 0.0924
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0032 0.0114 0.0295
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0052
Onchocerca volvulus 0.0032 0.0114 0.0139
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0102 0.0716 0.0722
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0149 0.1112 0.9407
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0184 0.0185
Toxoplasma gondii ABC1 family protein 0.0074 0.0478 0.1566
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0293 0.0296
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0049 0.006
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0032 0.0114 0.0886
Loa Loa (eye worm) fli-1 protein 0.0228 0.1784 0.1848
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0101 0.0704 0.2358
Loa Loa (eye worm) hypothetical protein 0.0076 0.049 0.0503
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0139 0.1029 0.2601
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0253 0.0255
Echinococcus granulosus traf and tnf receptor associated protein 0.0032 0.0114 0.0115
Loa Loa (eye worm) nuclear factor I 0.0019 0.0009 0.0003
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0478 0.0488
Loa Loa (eye worm) hypothetical protein 0.0176 0.1342 0.1388
Loa Loa (eye worm) hypothetical protein 0.0053 0.0293 0.0299
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0079
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Schistosoma mansoni RAR-like nuclear receptor 0.0053 0.0293 0.0293
Schistosoma mansoni ap endonuclease 0.0157 0.1181 0.1181
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0478 0.0478
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0704 0.1616
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0231 0.1812 0.1875
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.011 0.0281
Loa Loa (eye worm) hypothetical protein 0.003 0.0097 0.0095
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0083 0.0553 0.0553
Brugia malayi TAR-binding protein 0.0125 0.0911 0.0938
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0032 0.0114 0.0215
Brugia malayi Pre-SET motif family protein 0.0452 0.37 0.3836
Brugia malayi RNA binding protein 0.0125 0.0911 0.0938
Brugia malayi isocitrate dehydrogenase 0.005 0.0267 0.0269
Leishmania major endonuclease/exonuclease protein-like protein 0.0032 0.0114 0.0886
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.005 0.0051
Plasmodium vivax importin-beta 2, putative 0.003 0.0097 0.0578
Echinococcus granulosus dna polymerase kappa 0.0021 0.0024 0.0024
Brugia malayi mbt repeat family protein 0.0191 0.1471 0.1519
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0101 0.0704 0.5923
Brugia malayi nuclear receptor RXR 0.0028 0.0081 0.0076
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.011 0.0281
Brugia malayi latrophilin 2 splice variant baaae 0.0275 0.219 0.2267
Giardia lamblia hypothetical protein 0.0032 0.0114 0.0783
Echinococcus multilocularis thyroid hormone receptor alpha 0.0179 0.1373 0.1384
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.01 0.0694 0.0699
Loa Loa (eye worm) hypothetical protein 0.0032 0.0114 0.0113
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0127 0.093 0.0958
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0032 0.0114 0.0783
Schistosoma mansoni neutral sphingomyelinase 0.0032 0.0114 0.0114
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0777 0.1242
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0149 0.1112 0.94
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0777 0.1948
Mycobacterium tuberculosis Probable exported protein 0.0032 0.0114 0.0234
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0478 0.1079
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Schistosoma mansoni hypothetical protein 0.1182 0.9919 0.9919
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0478 0.0491
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0053 0.0293 0.0296
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0024 0.0111
Brugia malayi jmjC domain containing protein 0.004 0.0184 0.0182
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0278 0.0869
Toxoplasma gondii melibiase subfamily protein 0.01 0.0694 0.2321
Loa Loa (eye worm) beta-lactamase 0.0074 0.0478 0.0491
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0049 0.006
Onchocerca volvulus 0.0074 0.0478 0.101
Schistosoma mansoni inositol monophosphatase 0.0149 0.1112 0.1112
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0141 0.0142
Brugia malayi ecdysone receptor 0.0025 0.0056 0.0049
Onchocerca volvulus 0.0149 0.1113 0.2529
Loa Loa (eye worm) hypothetical protein 0.0054 0.0301 0.0306
Echinococcus multilocularis musashi 0.0028 0.0079 0.008
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0694 0.0694
Schistosoma mansoni synaptojanin 0.0032 0.0114 0.0114
Schistosoma mansoni jumonji domain containing protein 0.0081 0.0537 0.0537
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0157 0.1181 1
Toxoplasma gondii isocitrate dehydrogenase 0.005 0.0267 0.083
Echinococcus multilocularis lamin dm0 0.0028 0.0079 0.008
Loa Loa (eye worm) hypothetical protein 0.0217 0.1696 0.1756
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0032 0.0114 0.0886
Loa Loa (eye worm) hypothetical protein 0.0402 0.3276 0.3397
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0053 0.0293 0.0296
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0101 0.0704 0.0726
Echinococcus multilocularis mitogen activated protein kinase 0.0101 0.0704 0.071
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0218 0.1704 1
Onchocerca volvulus 0.0028 0.0079 0.0055
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0032 0.0114 0.0886
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.0293 0.0296
Loa Loa (eye worm) hypothetical protein 0.0066 0.0411 0.0421
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0056 0.0056
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0053 0.0293 0.0296
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0278 0.2156
Onchocerca volvulus 0.0074 0.0478 0.101
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0478 0.1174
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0032 0.0114 0.0115
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0052
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0114 0.011
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0056 0.0049
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0024 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Echinococcus granulosus polycomb protein SCMH1 0.0191 0.1471 0.1482
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0157 0.1181 0.1191
Echinococcus multilocularis dna polymerase eta 0.0021 0.0024 0.0024
Schistosoma mansoni zinc finger protein 0.0025 0.0056 0.0056
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0032 0.0114 0.0295
Loa Loa (eye worm) hypothetical protein 0.0046 0.0234 0.0237
Brugia malayi follicle stimulating hormone receptor 0.1148 0.9631 1
Echinococcus granulosus snurportin 1 0.0316 0.2537 0.2557
Echinococcus multilocularis mothers against decapentaplegic 5 0.0035 0.0141 0.0142
Brugia malayi Cytochrome P450 family protein 0.003 0.0099 0.0094
Schistosoma mansoni smad1 5 8 and 0.0035 0.0141 0.0141
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0704 0.1616
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0218 0.1704 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0053 0.0293 0.0299
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.003 0.0165
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0056 0.0052
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0253 0.0257
Loa Loa (eye worm) hypothetical protein 0.0053 0.0293 0.0299
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0024 0.0024
Brugia malayi beta-lactamase 0.0074 0.0478 0.0488
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0267 0.027
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0056 0.0057
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0127 0.093 0.0938
Brugia malayi nuclear receptor NHR-67 0.0025 0.0056 0.0049
Echinococcus multilocularis histone acetyltransferase MYST2 0.0217 0.1696 0.1709
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0157 0.1181 0.1173
Schistosoma mansoni 3-dehydroquinate synthase 0.0139 0.1029 0.1029
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0032 0.0114 0.0732
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.005 0.0267 0.2062
Plasmodium falciparum glutathione reductase 0.0048 0.0253 0.1939
Loa Loa (eye worm) DR-78 0.0025 0.0056 0.0052
Brugia malayi PHD-finger family protein 0.0027 0.0072 0.0066
Onchocerca volvulus 0.0515 0.4233 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0478 0.1174
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0081 0.0076
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0011 0.0005
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0114 0.011
Brugia malayi Bromodomain containing protein 0.0034 0.0132 0.0128
Brugia malayi Steroid receptor seven-up type 2 0.0053 0.0293 0.0296
Brugia malayi mbt repeat family protein 0.0191 0.1471 0.1519
Brugia malayi MH2 domain containing protein 0.0035 0.0141 0.0138
Schistosoma mansoni hypothetical protein 0.1182 0.9919 0.9919
Brugia malayi Smad1 0.0035 0.0141 0.0138
Echinococcus granulosus lamin dm0 0.0028 0.0079 0.008
Entamoeba histolytica hypothetical protein 0.0035 0.0141 0.1016
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0024 0.0111
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0184 0.0184
Trichomonas vaginalis Phospholipase C precursor, putative 0.0032 0.0114 0.0215
Plasmodium falciparum thioredoxin reductase 0.0048 0.0253 0.1939
Leishmania major hypothetical protein, conserved 0.0032 0.0114 0.0886
Echinococcus granulosus SAM and MBT domain containing protein 0.0191 0.1471 0.1482
Loa Loa (eye worm) hypothetical protein 0.0053 0.0293 0.0299
Mycobacterium ulcerans hypothetical protein 0.0074 0.0478 0.1623
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0397 0.0397
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0097 0.0734
Echinococcus multilocularis neuropeptide receptor A26 0.0457 0.3741 0.3772
Schistosoma mansoni thyroid hormone receptor 0.0179 0.1373 0.1373
Mycobacterium ulcerans aldehyde dehydrogenase 0.0118 0.0849 0.2914
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0478 0.1174
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0157 0.1181 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0478 0.1623
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0231 0.1812 0.1812
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0278 0.2156
Loa Loa (eye worm) isocitrate dehydrogenase 0.005 0.0267 0.0272
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0032 0.0114 0.0886
Plasmodium vivax hypothetical protein, conserved 0.0031 0.011 0.0699
Giardia lamblia PHD finger protein 15 0.0031 0.011 0.075
Brugia malayi beta-lactamase family protein 0.0074 0.0478 0.0488
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0127 0.093 0.0938
Leishmania major hypothetical protein, conserved 0.0032 0.0114 0.0886
Schistosoma mansoni nuclear receptor 0.0025 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0032 0.0114 0.0113
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0056 0.0057
Loa Loa (eye worm) hypothetical protein 0.0041 0.0195 0.0196
Schistosoma mansoni hypothetical protein 0.0023 0.0039 0.0039
Schistosoma mansoni lamin 0.0028 0.0079 0.0079
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0053 0.0293 0.0296
Loa Loa (eye worm) RNA binding protein 0.0125 0.0911 0.0941
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0024 0.0024
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0056 0.0056
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0478 0.1174
Loa Loa (eye worm) latrophilin receptor protein 2 0.0127 0.093 0.096
Loa Loa (eye worm) hypothetical protein 0.0074 0.0478 0.0491
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0694 0.0694
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0032 0.0114 0.0215
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0032 0.0114 0.0886
Onchocerca volvulus 0.0317 0.2549 0.5968
Trichomonas vaginalis conserved hypothetical protein 0.0168 0.1273 0.2969
Echinococcus granulosus histone lysine methyltransferase setb 0.0083 0.0553 0.0558
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0101 0.0704 0.5923
Brugia malayi CCR4 0.0032 0.0114 0.011
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0293 0.0296
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0911 0.0911
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0122 0.0881 0.2217
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0056 0.0057
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0081 0.0082
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0053 0.0293 0.0296
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0777 0.1948
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0056 0.0056
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0777 0.1948
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0053 0.0293 0.0293
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0032 0.0114 0.0115
Onchocerca volvulus Alhambra homolog 0.0031 0.011 0.013
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0024 0.0045
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0056 0.0052
Mycobacterium ulcerans aldehyde dehydrogenase 0.0118 0.0849 0.2914
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0478 0.0482
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0052
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0053 0.0293 0.0296
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0053 0.0293 0.0296
Schistosoma mansoni inositol monophosphatase 0.0149 0.1112 0.1112
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0149 0.1112 0.3826
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.011 0.0109
Brugia malayi MH2 domain containing protein 0.0511 0.4201 0.4357
Loa Loa (eye worm) hypothetical protein 0.0729 0.6062 0.6292
Onchocerca volvulus 0.0065 0.0397 0.0817
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0056 0.0057
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0389 0.0392
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0056 0.0056
Leishmania major trypanothione reductase 0.0048 0.0253 0.2073
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0316 0.2537 0.263
Leishmania major hypothetical protein, conserved 0.0074 0.0478 0.399
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.0293 0.0296
Echinococcus granulosus histone acetyltransferase MYST2 0.0217 0.1696 0.1709
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.0293 0.0293
Schistosoma mansoni hypothetical protein 0.0127 0.093 0.093
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0056 0.0049
Leishmania major RNA-editing complex protein MP100, putative 0.0032 0.0114 0.0886
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0032 0.0114 0.0732
Brugia malayi nuclear hormone receptor 0.0025 0.0056 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0032 0.0114 0.0886
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0114 0.0886
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0053 0.0293 0.0296
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0694 0.0694
Schistosoma mansoni synaptojanin 0.0032 0.0114 0.0114
Brugia malayi Thioredoxin reductase 0.0048 0.0253 0.0254
Schistosoma mansoni smad1 5 8 and 0.0035 0.0141 0.0141
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0032 0.0114 0.0886
Loa Loa (eye worm) hypothetical protein 0.0127 0.093 0.096
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0066 0.0411 0.092
Treponema pallidum exodeoxyribonuclease (exoA) 0.0157 0.1181 0.6713
Leishmania major DNA polymerase eta, putative 0.0021 0.0024 0.0111
Giardia lamblia Kinase, CMGC MAPK 0.0101 0.0704 0.5877
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0397 0.0401
Schistosoma mansoni gabp alpha 0.0075 0.0483 0.0483
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0777 0.1948
Loa Loa (eye worm) hypothetical protein 0.0074 0.0478 0.0491
Schistosoma mansoni sex comb on midleg homolog 0.0191 0.1471 0.1471
Brugia malayi Bromodomain containing protein 0.0041 0.0194 0.0193
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0911 0.0911
Brugia malayi glutathione reductase 0.0048 0.0253 0.0254
Loa Loa (eye worm) steroid hormone receptor 0.0053 0.0293 0.0299
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0217 0.1696 0.1753
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0083 0.0553 0.0553
Echinococcus multilocularis geminin 0.1182 0.9919 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0101 0.0704 0.5923
Loa Loa (eye worm) hypothetical protein 0.0053 0.0293 0.0299
Brugia malayi Inositol-1 0.0149 0.1112 0.1147
Echinococcus multilocularis FTZ F1 alpha 0.0053 0.0293 0.0296
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0478 0.1079
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0114 0.0732
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0172 0.0174
Brugia malayi hypothetical protein 0.0729 0.6062 0.6291
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0217 0.1696 0.1709
Onchocerca volvulus Bile acid receptor homolog 0.0053 0.0293 0.0568
Brugia malayi RNA recognition motif domain containing protein 0.0125 0.0911 0.0938
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0053 0.0293 0.0296
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0231 0.1812 0.1827
Plasmodium vivax glutathione reductase, putative 0.0048 0.0253 0.1939
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0911 0.0911
Brugia malayi hypothetical protein 0.0035 0.0141 0.0138
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0218 0.1704 0.3627
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0035 0.0141 0.0141
Echinococcus multilocularis tumor protein p63 0.037 0.2998 0.3022
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0267 0.2193
Schistosoma mansoni carbon catabolite repressor protein 0.0032 0.0114 0.0114
Schistosoma mansoni hypothetical protein 0.0127 0.093 0.093
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0053 0.0293 0.0296
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0053 0.0293 0.0296
Schistosoma mansoni smad1 5 8 and 0.0035 0.0141 0.0141
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0253 0.0594
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0191 0.1471 0.3387
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0114 0.0886
Brugia malayi conserved hypotetical protein 0.0025 0.0056 0.0049
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0139 0.1029 0.2601
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0053 0.0293 0.0568
Schistosoma mansoni sex comb on midleg homolog 0.0191 0.1471 0.1471
Loa Loa (eye worm) hypothetical protein 0.0053 0.0293 0.0299
Plasmodium vivax SET domain protein, putative 0.0065 0.0397 0.3191
Trichomonas vaginalis ap endonuclease, putative 0.0157 0.1181 0.2751
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0053 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0052
Echinococcus granulosus synaptojanin 1 0.0032 0.0114 0.0115
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0478 0.399
Loa Loa (eye worm) hypothetical protein 0.0053 0.0293 0.0299
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0881 0.2217
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0139 0.1029 0.2288
Brugia malayi Melibiase family protein 0.0066 0.0411 0.0418
Schistosoma mansoni hypothetical protein 0.0022 0.0033 0.0033
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0101 0.0704 0.5923
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0052
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0278 0.2286
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.005 0.0267 0.027
Brugia malayi MAP kinase sur-1 0.0101 0.0704 0.0723
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0101 0.0704 0.5923
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0293 0.0296
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0357 0.2889 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0052
Leishmania major GTP-binding protein, putative 0.0022 0.003 0.0165
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0114 0.011
Toxoplasma gondii exonuclease III APE 0.0157 0.1181 0.4027
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0032 0.0114 0.0783
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0478 0.1079
Toxoplasma gondii aldehyde dehydrogenase 0.0118 0.0849 0.2866
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0032 0.0114 0.0886
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0127 0.093 0.0938
Echinococcus multilocularis GPCR, family 2 0.0127 0.093 0.0938
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0053 0.0293 0.0299
Onchocerca volvulus 0.0191 0.1471 0.3387
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0157 0.1181 0.4068
Schistosoma mansoni bromodomain containing protein 0.0068 0.0422 0.0422
Echinococcus multilocularis synaptojanin 1 0.0032 0.0114 0.0115
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0783 0.6523 0.6576
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0157 0.1181 1
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0032 0.0114 0.0732
Echinococcus granulosus importin subunit beta 1 0.003 0.0097 0.0097
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0704 0.0704
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0114 0.0886
Brugia malayi Latrophilin receptor protein 2 0.0127 0.093 0.0958
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0032 0.0114 0.0886
Echinococcus granulosus GA binding protein alpha chain 0.0075 0.0483 0.0487
Loa Loa (eye worm) hypothetical protein 0.0053 0.0293 0.0299
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0127 0.0924 0.0932
Brugia malayi photoreceptor-specific nuclear receptor 0.0053 0.0293 0.0296
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0024 0.0111
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0062 0.0377 0.038
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0704 0.1616
Leishmania major DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0024 0.0111
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0056 0.0057
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0217 0.1696 0.1709
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0032 0.0114 0.0215
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0114 0.011
Loa Loa (eye worm) hypothetical protein 0.0074 0.0478 0.0491
Plasmodium falciparum DNase I-like protein, putative 0.0032 0.0114 0.0732
Loa Loa (eye worm) hypothetical protein 0.0027 0.0075 0.0072
Echinococcus multilocularis neutral sphingomyelinase 0.0032 0.0114 0.0115
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0475 0.3891 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0122 0.0881 0.1673
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0032 0.0114 0.0783
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0056 0.0057
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0032 0.0114 0.0295
Onchocerca volvulus Putative neutral sphingomyelinase 0.0032 0.0114 0.0139
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0215 0.0216
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0099 0.0097
Brugia malayi Ets-domain containing protein 0.0075 0.0483 0.0493
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0127 0.093 0.0938
Onchocerca volvulus 0.0054 0.0306 0.0598
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0478 0.1079
Echinococcus multilocularis GA binding protein alpha chain 0.0075 0.0483 0.0487
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0184 0.0185
Loa Loa (eye worm) MH2 domain-containing protein 0.0511 0.4201 0.4359
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0157 0.1181 1
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0218 0.1704 0.5883
Loa Loa (eye worm) hypothetical protein 0.0074 0.0478 0.0491
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0911 0.0911
Loa Loa (eye worm) CYP4Cod1 0.002 0.0011 0.0005
Schistosoma mansoni thyroid hormone receptor 0.0179 0.1373 0.1373
Trypanosoma cruzi mitochondrial protein 99, putative 0.0032 0.0114 0.0886
Leishmania major hypothetical protein, conserved 0.0032 0.0114 0.0886
Echinococcus granulosus zinc finger protein 0.0021 0.0023 0.0023
Trichomonas vaginalis set domain proteins, putative 0.0515 0.4233 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0122 0.0881 0.2217
Echinococcus multilocularis neuropeptide s receptor 0.0457 0.3741 0.3772
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0032 0.0114 0.0113
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0032 0.0114 0.0113
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0397 0.1285
Echinococcus granulosus mitogen activated protein kinase 0.0101 0.0704 0.071
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0478 0.1174
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.003 0.0025
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0278 0.2286
Entamoeba histolytica hypothetical protein 0.0035 0.0141 0.1016
Loa Loa (eye worm) Smad1 0.0035 0.0141 0.0141
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Plasmodium falciparum importin beta, putative 0.003 0.0097 0.0578
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0357 0.2889 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0149 0.1112 0.9407
Brugia malayi hypothetical protein 0.0033 0.0124 0.012
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0053 0.0293 0.0299
Brugia malayi jmjC domain containing protein 0.0102 0.0716 0.0735
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0149 0.1112 0.9407
Loa Loa (eye worm) hypothetical protein 0.0317 0.2549 0.2642
Loa Loa (eye worm) hypothetical protein 0.0191 0.1471 0.1522
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0114 0.011
Echinococcus multilocularis isocitrate dehydrogenase 0.005 0.0267 0.027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0231 0.1812 0.1812
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.003 0.0022
Echinococcus granulosus survival motor neuron protein 1 0.0729 0.6062 0.6111
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0394 0.0403
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0149 0.1112 0.2586
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0157 0.1181 0.2993
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.01 0.0694 0.0699
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.003 0.0165
Schistosoma mansoni importin beta-1 0.003 0.0097 0.0097
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0267 0.027
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0215 0.0216
Leishmania major pantothenate kinase subunit, putative 0.0032 0.0114 0.0886
Brugia malayi nuclear receptor NHR-88 0.0025 0.0056 0.0049
Giardia lamblia Inositol 5-phosphatase 4 0.0032 0.0114 0.0783
Echinococcus granulosus neuropeptide receptor A26 0.0457 0.3741 0.3772
Brugia malayi nuclear hormone receptor 0.0053 0.0293 0.0296
Schistosoma mansoni lamin 0.0028 0.0079 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.0293 0.0296
Trypanosoma cruzi mitochondrial protein 99, putative 0.0032 0.0114 0.0886
Loa Loa (eye worm) hypothetical protein 0.0275 0.219 0.2269
Brugia malayi RNA, U transporter 1 0.0084 0.0562 0.0575
Echinococcus granulosus dna polymerase eta 0.0021 0.0024 0.0024
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0231 0.1812 0.1827
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0139 0.1029 0.354
Echinococcus granulosus intermediate filament protein 0.0028 0.0079 0.008
Loa Loa (eye worm) hypothetical protein 0.0028 0.0079 0.0076
Loa Loa (eye worm) hypothetical protein 0.0074 0.0478 0.0491
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0081 0.0079
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0231 0.1812 0.1877
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0032 0.0114 0.0113
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.003 0.003
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0478 0.1174
Brugia malayi tailless protein 0.0025 0.0056 0.0049
Onchocerca volvulus 0.0074 0.0478 0.101
Brugia malayi Pre-SET motif family protein 0.0065 0.0397 0.0404
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0053 0.0293 0.0296
Echinococcus multilocularis zinc finger protein 0.0021 0.0023 0.0023
Mycobacterium ulcerans aldehyde dehydrogenase 0.0118 0.0849 0.2914
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.005 0.005
Echinococcus multilocularis peregrin 0.0034 0.0132 0.0133
Entamoeba histolytica hypothetical protein 0.0035 0.0141 0.1016
Loa Loa (eye worm) TAR-binding protein 0.0125 0.0911 0.0941
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0032 0.0114 0.0732
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0024 0.0111
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0053 0.0293 0.0299
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0032 0.0114 0.0732
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0032 0.0114 0.0113
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.005 0.0267 0.027
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0267 0.2193
Echinococcus multilocularis tar DNA binding protein 0.0125 0.0911 0.0919
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0079
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0816 0.6801 0.6857
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0293 0.0296
Brugia malayi Bromodomain containing protein 0.008 0.0529 0.0541
Loa Loa (eye worm) inositol-1 0.0149 0.1112 0.1149
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0049 0.006
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0149 0.1112 0.2586
Echinococcus multilocularis Smad4 0.0035 0.0141 0.0142
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0125 0.0911 0.0941
Echinococcus granulosus tar DNA binding protein 0.0125 0.0911 0.0919
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.011 0.011
Schistosoma mansoni steroid hormone receptor ad4bp 0.0053 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.0054 0.0306 0.0312
Schistosoma mansoni cript-related 0.0032 0.0114 0.0114
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0176 0.1342 0.1386
Loa Loa (eye worm) transcription factor SMAD2 0.0511 0.4201 0.4359
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.011 0.0111
Echinococcus granulosus neuropeptide s receptor 0.0457 0.3741 0.3772
Brugia malayi hypothetical protein 0.0028 0.0081 0.0076
Loa Loa (eye worm) MBCTL1 0.0217 0.1696 0.1756
Echinococcus multilocularis ecdysone induced protein 78C 0.0053 0.0293 0.0296
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0097 0.0734
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0032 0.0114 0.0215
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.003 0.0165
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0039 0.0039
Leishmania major importin beta-1 subunit, putative 0.0024 0.0049 0.0327
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0118 0.0849 0.0856
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0157 0.1181 0.1191
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0032 0.0114 0.0115
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0097 0.0233
Schistosoma mansoni ets-related 0.0228 0.1784 0.1784
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0032 0.0114 0.0215
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0157 0.1181 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0157 0.1181 1
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0114 0.0886
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0079 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0053 0.0293 0.0299
Loa Loa (eye worm) hypothetical protein 0.0044 0.0216 0.0219
Loa Loa (eye worm) mbt repeat family protein 0.0191 0.1471 0.1522
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0231 0.1812 0.1812
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0052
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0389 0.0392
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0253 0.0255
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0149 0.1112 0.9407
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Loa Loa (eye worm) hypothetical protein 0.0031 0.011 0.0109
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0777 0.1948
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0149 0.1112 0.3785
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.005 0.0267 0.0267
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0024 0.0111
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0694 0.0694
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0357 0.2889 1
Entamoeba histolytica hypothetical protein 0.0024 0.0049 0.0218
Brugia malayi MH2 domain containing protein 0.0035 0.0141 0.0138
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0114 0.011
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0081 0.0081
Loa Loa (eye worm) MH1 domain-containing protein 0.0035 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0028 0.0081 0.0079
Onchocerca volvulus Protein ultraspiracle homolog 0.0053 0.0293 0.0568
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0478 0.1623
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0056 0.0049
Echinococcus granulosus geminin 0.1182 0.9919 1
Echinococcus granulosus peregrin 0.0034 0.0132 0.0133
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0253 0.1939
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0053 0.0293 0.0296
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0478 0.1174
Brugia malayi hypothetical protein 0.0317 0.2549 0.264
Brugia malayi exodeoxyribonuclease III family protein 0.0157 0.1181 0.1219
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0114 0.0886
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0032 0.0114 0.0886
Brugia malayi MH1 domain containing protein 0.0035 0.0141 0.0138
Schistosoma mansoni coup transcription factor 0.0053 0.0293 0.0293
Brugia malayi MH1 domain containing protein 0.0035 0.0141 0.0138
Schistosoma mansoni ran 0.0022 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0052
Schistosoma mansoni ran 0.0022 0.003 0.003
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0141 0.0141
Schistosoma mansoni retinoic acid receptor RXR 0.0053 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.0083 0.0553 0.0569
Mycobacterium tuberculosis Conserved protein 0.0074 0.0478 0.1174
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0032 0.0114 0.0886
Trichomonas vaginalis esterase, putative 0.0074 0.0478 0.1079
Leishmania major hypothetical protein, conserved 0.0051 0.0278 0.2286
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0024 0.0024
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0081 0.0076
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0032 0.0114 0.0886
Schistosoma mansoni hypothetical protein 0.0035 0.0141 0.0141
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.005 0.0267 0.027
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0411 0.0411
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0478 0.0482
Echinococcus multilocularis Glycoside hydrolase, family 27 0.01 0.0694 0.0699
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0053 0.0293 0.0293
Echinococcus granulosus GPCR family 2 0.0127 0.093 0.0938
Schistosoma mansoni nuclear receptor 0.0025 0.0056 0.0056
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.005 0.0051
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0293 0.0296
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0056 0.0049
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0357 0.2889 1
Echinococcus multilocularis lamin 0.0028 0.0079 0.008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.0293 0.0296
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0032 0.0114 0.0113
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0141 0.0142
Trypanosoma brucei unspecified product 0.0021 0.0024 0.0111
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0035 0.0141 0.0142
Brugia malayi hypothetical protein 0.0028 0.0081 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0172 0.0174
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0039 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0278 0.2286
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0056 0.0057
Trypanosoma brucei trypanothione reductase 0.0048 0.0253 0.2073
Brugia malayi PHD-finger family protein 0.0031 0.011 0.0106
Trichomonas vaginalis ran, putative 0.0022 0.003 0.0015
Schistosoma mansoni aldehyde dehydrogenase 0.0118 0.0849 0.0849
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0032 0.0114 0.0783
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0118 0.0849 0.2135
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0053 0.0293 0.0296
Toxoplasma gondii thioredoxin reductase 0.0048 0.0253 0.0781
Brugia malayi hypothetical protein 0.0025 0.0056 0.0049
Echinococcus multilocularis deoxyribonuclease 1 2 0.0032 0.0114 0.0115
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0033 0.0028
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0032 0.0114 0.0215
Echinococcus granulosus inositol monophosphatase 1 0.0149 0.1112 0.1121
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0056 0.0057
Echinococcus granulosus mitogen activated protein kinase 3 0.0101 0.0704 0.071
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0032 0.0114 0.011
Brugia malayi Cytochrome P450 family protein 0.002 0.0011 0.0002
Brugia malayi ecdysteroid receptor 0.0053 0.0293 0.0296
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0032 0.0114 0.0783
Schistosoma mansoni hypothetical protein 0.0275 0.219 0.219
Loa Loa (eye worm) glutathione reductase 0.0048 0.0253 0.0257
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0397 0.0397
Schistosoma mansoni DNA polymerase eta 0.0021 0.0024 0.0024
Trichomonas vaginalis inositol monophosphatase, putative 0.0149 0.1112 0.2586
Echinococcus granulosus mothers against decapentaplegic 5 0.0035 0.0141 0.0142
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0064 0.0391 0.04
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.0293 0.0296
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0032 0.0114 0.0783
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0402 0.3276 0.3397
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0053 0.0293 0.0299
Onchocerca volvulus 0.0053 0.0293 0.0568
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0452 0.37 0.3838
Echinococcus multilocularis inositol monophosphatase 1 0.0149 0.1112 0.1121
Mycobacterium tuberculosis Conserved protein 0.0074 0.0478 0.1174
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0253 0.2073
Loa Loa (eye worm) hypothetical protein 0.0021 0.0024 0.0019
Schistosoma mansoni ap endonuclease 0.0157 0.1181 0.1181
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0118 0.0849 0.0856
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0478 0.3889
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0118 0.0849 0.7163
Schistosoma mansoni intermediate filament proteins 0.0028 0.0079 0.0079
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0024 0.0016
Schistosoma mansoni Smad4 0.0035 0.0141 0.0141
Echinococcus granulosus Smad4 0.0035 0.0141 0.0142
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0011 0.0005
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0056 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0024 0.0111
Loa Loa (eye worm) hypothetical protein 0.0053 0.0293 0.0299
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.005 0.0267 0.2193
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0133 0.0979 0.2079
Echinococcus granulosus smad 0.0035 0.0141 0.0142
Schistosoma mansoni nuclear hormone receptor 0.0053 0.0293 0.0293
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0032 0.0114 0.0295
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0053 0.0293 0.0293
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0032 0.0114 0.0295
Loa Loa (eye worm) hypothetical protein 0.0074 0.0478 0.0491
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0231 0.1812 0.1827
Trypanosoma brucei protein kinase, putative 0.0101 0.0704 0.5923
Schistosoma mansoni nocturnin 0.0032 0.0114 0.0114
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0053 0.0293 0.0293
Schistosoma mansoni myelin transcription factor 1 myt1 0.0217 0.1696 0.1696
Trypanosoma brucei RNA editing exonuclease 2 0.0032 0.0114 0.0886
Echinococcus granulosus TGF beta signal transducer SmadC 0.0035 0.0141 0.0142
Echinococcus granulosus FTZ F1 alpha 0.0053 0.0293 0.0296
Plasmodium vivax exodeoxyribonuclease III, putative 0.0032 0.0114 0.0732
Brugia malayi nuclear receptor RXR 0.0025 0.0056 0.0049
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.003 0.0055
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0032 0.0114 0.0114

Activities

Activity type Activity value Assay description Source Reference
Kd (binding) = 15 nM Dissociation constant against EPSP synthase ChEMBL. No reference
Ki (binding) 0.11 nM Inhibition of EPSP synthase PEP-Pi site by the compound was expressed as apparent value ChEMBL. No reference
Ki (binding) = 15 nM Potency of the compound was determined against EPSP synthase ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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