Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0055 | 0.1094 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0022 | 0.0108 | 0.0083 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0034 | 0.0469 | 0.0365 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0055 | 0.1094 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0166 | 0.4424 | 0.4364 |
Schistosoma mansoni | thyroid hormone receptor | 0.0351 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0186 | 0.5021 | 0.5009 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0127 | 0.326 | 0.3243 |
Brugia malayi | Muscleblind-like protein | 0.0127 | 0.326 | 0.326 |
Schistosoma mansoni | tar DNA-binding protein | 0.0047 | 0.0862 | 0.0763 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0022 | 0.0108 | 0.0083 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0034 | 0.0461 | 0.0357 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0351 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0351 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0288 | 0.8093 | 0.8093 |
Schistosoma mansoni | nuclear receptor | 0.0166 | 0.4424 | 0.4364 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0351 | 1 | 1 |
Onchocerca volvulus | Arrow homolog | 0.0046 | 0.0822 | 0.0379 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0351 | 1 | 1 |
Brugia malayi | Trypsin family protein | 0.0034 | 0.0461 | 0.0461 |
Echinococcus multilocularis | laminin | 0.0046 | 0.0822 | 0.08 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0351 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0096 | 0.2332 | 0.2249 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0351 | 1 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0166 | 0.4424 | 0.4411 |
Schistosoma mansoni | hypothetical protein | 0.0246 | 0.6849 | 0.6815 |
Loa Loa (eye worm) | trypsin family protein | 0.0034 | 0.0461 | 0.0461 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0166 | 0.4424 | 0.4424 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0461 | 0.0461 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0034 | 0.0461 | 0.0438 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0186 | 0.5021 | 0.5021 |
Brugia malayi | conserved hypotetical protein | 0.0166 | 0.4424 | 0.4424 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0166 | 0.4424 | 0.4411 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0046 | 0.0832 | 0.081 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.002 | 0.0043 | 0.0019 |
Brugia malayi | mbt repeat family protein | 0.0041 | 0.0664 | 0.0664 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0351 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0022 | 0.0108 | 0.0083 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0186 | 0.5021 | 0.5021 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0351 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0351 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0047 | 0.0862 | 0.0862 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0166 | 0.4424 | 0.4424 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0055 | 0.1094 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0351 | 1 | 1 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0046 | 0.0832 | 0.0732 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0351 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0047 | 0.0862 | 0.084 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0186 | 0.5021 | 0.5009 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0351 | 1 | 1 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.002 | 0.0043 | 0.0019 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0351 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0028 | 0.0295 | 0.0295 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0022 | 0.0108 | 0.0083 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0034 | 0.0469 | 0.0365 |
Brugia malayi | tailless protein | 0.0166 | 0.4424 | 0.4424 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0351 | 1 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0166 | 0.4424 | 0.4364 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0351 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0047 | 0.0862 | 0.0763 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0046 | 0.0822 | 0.0822 |
Echinococcus multilocularis | muscleblind protein | 0.0127 | 0.326 | 0.3243 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0034 | 0.0469 | 0.0445 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Echinococcus multilocularis | fibrillin 1 | 0.0046 | 0.0822 | 0.08 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0022 | 0.0108 | 0.0083 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0041 | 0.0664 | 0.0562 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0351 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Brugia malayi | mbt repeat family protein | 0.0041 | 0.0664 | 0.0664 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0046 | 0.0832 | 0.081 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0351 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0095 | 0.0095 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0041 | 0.0664 | 0.0664 |
Schistosoma mansoni | tar DNA-binding protein | 0.0047 | 0.0862 | 0.0763 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0166 | 0.4424 | 0.4424 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0022 | 0.0108 | 0.0083 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0186 | 0.5021 | 0.5021 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0022 | 0.0108 | 0.0083 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0292 | 0.8206 | 0.8187 |
Onchocerca volvulus | 0.0041 | 0.0664 | 0.0212 | |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0166 | 0.4424 | 0.4411 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0166 | 0.4424 | 0.4155 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0022 | 0.0108 | 0.0083 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0041 | 0.0664 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0351 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0664 | 0.0664 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0351 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0166 | 0.4424 | 0.4411 |
Brugia malayi | nuclear receptor RXR | 0.0166 | 0.4424 | 0.4424 |
Loa Loa (eye worm) | SRC-1 | 0.0022 | 0.0108 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0461 | 0.0461 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0022 | 0.0108 | 0.0083 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0046 | 0.0832 | 0.081 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1094 | 0.1094 |
Schistosoma mansoni | nuclear hormone receptor | 0.0351 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.326 | 0.326 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.005 | 0.0935 | 0.0935 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0935 | 0.0935 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0351 | 1 | 1 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0034 | 0.0461 | 0.0438 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0109 | 0.2733 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0034 | 0.0461 | 0.0438 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.016 | 0.4245 | 0.4231 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0022 | 0.0108 | 0.0083 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0186 | 0.5021 | 0.4967 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Onchocerca volvulus | 0.0351 | 1 | 1 | |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0046 | 0.0832 | 0.0832 |
Loa Loa (eye worm) | hypothetical protein | 0.0351 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0047 | 0.0862 | 0.0862 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.002 | 0.0043 | 0.0019 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0041 | 0.0664 | 0.0641 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0166 | 0.4424 | 0.4424 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0351 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0166 | 0.4424 | 0.4364 |
Brugia malayi | Cytochrome P450 family protein | 0.0028 | 0.0295 | 0.0295 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0038 | 0.0574 | 0.0471 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.326 | 0.326 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0351 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0351 | 1 | 1 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0034 | 0.0461 | 0.0438 |
Echinococcus granulosus | Mastin | 0.0034 | 0.0461 | 0.0438 |
Brugia malayi | Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit | 0.0096 | 0.2332 | 0.2332 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0351 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0351 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Schistosoma mansoni | nuclear hormone receptor | 0.0166 | 0.4424 | 0.4364 |
Brugia malayi | nuclear receptor NHR-67 | 0.0166 | 0.4424 | 0.4424 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0351 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0351 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0109 | 0.2733 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0047 | 0.0862 | 0.084 |
Schistosoma mansoni | coup transcription factor | 0.0351 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0351 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0047 | 0.0862 | 0.0763 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0022 | 0.0108 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0822 | 0.0822 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0034 | 0.0469 | 0.0469 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.002 | 0.0043 | 0.0019 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0351 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0166 | 0.4424 | 0.4424 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0034 | 0.0469 | 0.0365 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0351 | 1 | 1 |
Echinococcus granulosus | tyrosine kinase | 0.002 | 0.0043 | 0.0019 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0351 | 1 | 1 |
Brugia malayi | Fibulin-1 precursor | 0.0046 | 0.0822 | 0.0822 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0186 | 0.5021 | 0.4967 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0022 | 0.0108 | 0.0083 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0041 | 0.0664 | 0.0641 |
Brugia malayi | nuclear receptor RXR | 0.0186 | 0.5021 | 0.5021 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0034 | 0.0469 | 0.0445 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0461 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0351 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0351 | 1 | 1 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.016 | 0.4245 | 0.4231 |
Brugia malayi | hypothetical protein | 0.0186 | 0.5021 | 0.5021 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0166 | 0.4424 | 0.4364 |
Echinococcus multilocularis | Mastin | 0.0034 | 0.0461 | 0.0438 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0047 | 0.0862 | 0.0862 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0034 | 0.0461 | 0.0438 |
Schistosoma mansoni | thyroid hormone receptor | 0.0351 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0166 | 0.4424 | 0.4411 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Mycobacterium ulcerans | hypothetical protein | 0.0034 | 0.0461 | 0.1687 |
Loa Loa (eye worm) | MBCTL1 | 0.0046 | 0.0832 | 0.0832 |
Loa Loa (eye worm) | hypothetical protein | 0.0351 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0461 | 0.0461 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0109 | 0.2733 | 0.5 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0034 | 0.0461 | 0.0461 |
Echinococcus granulosus | FTZ F1 alpha | 0.0351 | 1 | 1 |
Brugia malayi | protein-tyrosine kinase | 0.002 | 0.0043 | 0.0043 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0096 | 0.2332 | 0.2314 |
Echinococcus multilocularis | potassium voltage gated channel subfamily A | 0.0092 | 0.2206 | 0.2187 |
Onchocerca volvulus | 0.0166 | 0.4424 | 0.4155 | |
Onchocerca volvulus | 0.0254 | 0.7078 | 0.6937 | |
Echinococcus granulosus | laminin | 0.0046 | 0.0822 | 0.08 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0109 | 0.2733 | 0.2654 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0034 | 0.0469 | 0.0445 |
Brugia malayi | hypothetical protein | 0.0186 | 0.5021 | 0.5021 |
Loa Loa (eye worm) | DR-78 | 0.0166 | 0.4424 | 0.4424 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0041 | 0.0664 | 0.0562 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0055 | 0.1094 | 0.1073 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0166 | 0.4424 | 0.4411 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0351 | 1 | 1 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0166 | 0.4424 | 0.4364 |
Loa Loa (eye worm) | TAR-binding protein | 0.0047 | 0.0862 | 0.0862 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0166 | 0.4424 | 0.4424 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0351 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0109 | 0.2733 | 0.2715 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0461 | 0.0461 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0351 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0351 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0351 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0351 | 1 | 1 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0046 | 0.0832 | 0.081 |
Brugia malayi | Kringle domain containing protein | 0.0055 | 0.1094 | 0.1094 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0351 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0288 | 0.8093 | 0.8073 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.5021 | 0.5021 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0034 | 0.0461 | 0.0461 |
Echinococcus granulosus | muscleblind protein | 0.0127 | 0.326 | 0.3243 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0046 | 0.0822 | 0.0822 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0351 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0351 | 1 | 1 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0166 | 0.4424 | 0.4424 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0034 | 0.0461 | 0.0438 |
Brugia malayi | RNA binding protein | 0.0047 | 0.0862 | 0.0862 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0109 | 0.2733 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0461 | 0.0461 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0351 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0351 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Onchocerca volvulus | 0.0288 | 0.8093 | 0.8001 | |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0034 | 0.0461 | 0.0438 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0022 | 0.0108 | 0.0083 |
Echinococcus granulosus | potassium voltage gated channel subfamily A | 0.0096 | 0.2332 | 0.2314 |
Brugia malayi | nuclear hormone receptor | 0.0166 | 0.4424 | 0.4424 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0096 | 0.2332 | 0.2249 |
Loa Loa (eye worm) | hypothetical protein | 0.0351 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0022 | 0.0108 | 0.0083 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Schistosoma mansoni | egf-like domain protein | 0.0046 | 0.0822 | 0.0722 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.1094 | 0.0998 |
Toxoplasma gondii | kringle domain-containing protein | 0.0055 | 0.1094 | 0.1424 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0351 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0034 | 0.0469 | 0.0445 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0166 | 0.4424 | 0.4424 |
Schistosoma mansoni | tar DNA-binding protein | 0.0047 | 0.0862 | 0.0763 |
Loa Loa (eye worm) | hypothetical protein | 0.0351 | 1 | 1 |
Brugia malayi | Trypsin family protein | 0.0034 | 0.0461 | 0.0461 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.002 | 0.0043 | 0.0019 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0041 | 0.0664 | 0.0562 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0351 | 1 | 1 |
Echinococcus multilocularis | enteropeptidase | 0.0034 | 0.0461 | 0.0438 |
Brugia malayi | SRC-1 | 0.0022 | 0.0108 | 0.0108 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0055 | 0.1094 | 0.1073 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0022 | 0.0108 | 0.0083 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0166 | 0.4424 | 0.4411 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0166 | 0.4424 | 0.4411 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Brugia malayi | Trypsin family protein | 0.0034 | 0.0461 | 0.0461 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0046 | 0.0822 | 0.0822 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0041 | 0.0664 | 0.0641 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Brugia malayi | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Brugia malayi | ecdysone receptor | 0.0166 | 0.4424 | 0.4424 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0351 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0351 | 1 | 1 |
Echinococcus granulosus | Tolloid protein 1 | 0.005 | 0.0935 | 0.0913 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0461 | 0.0357 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0166 | 0.4424 | 0.4411 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0109 | 0.2733 | 1 |
Onchocerca volvulus | 0.0166 | 0.4424 | 0.4155 | |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.5021 | 0.5021 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0166 | 0.4424 | 0.4411 |
Loa Loa (eye worm) | TK protein kinase | 0.002 | 0.0043 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0461 | 0.0461 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0022 | 0.0095 | 0.0095 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0351 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0022 | 0.0108 | 0.0083 |
Leishmania major | hypothetical protein, conserved | 0.0055 | 0.1094 | 0.4004 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.005 | 0.0935 | 0.0836 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0351 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0832 | 0.0832 |
Loa Loa (eye worm) | hypothetical protein | 0.0288 | 0.8093 | 0.8093 |
Brugia malayi | TAR-binding protein | 0.0047 | 0.0862 | 0.0862 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0351 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0109 | 0.2733 | 1 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0046 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0351 | 1 | 1 |
Brugia malayi | Trypsin family protein | 0.0288 | 0.8093 | 0.8093 |
Echinococcus multilocularis | Tolloid protein 1 | 0.005 | 0.0935 | 0.0913 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0109 | 0.2733 | 0.2715 |
Loa Loa (eye worm) | hypothetical protein | 0.0351 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0351 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0166 | 0.4424 | 0.4411 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.2332 | 0.2332 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.1207 | 0.1207 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0351 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0166 | 0.4424 | 0.4411 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0351 | 1 | 1 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0096 | 0.2332 | 0.2314 |
Trypanosoma brucei | cytochrome P450, putative | 0.0018 | 0 | 0.5 |
Onchocerca volvulus | 0.0055 | 0.1094 | 0.0664 | |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0109 | 0.2733 | 0.2654 |
Brugia malayi | Protein kinase domain containing protein | 0.0056 | 0.1113 | 0.1113 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0034 | 0.0469 | 0.0469 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0056 | 0.1113 | 0.1113 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0034 | 0.0461 | 0.0438 |
Brugia malayi | nuclear receptor NHR-88 | 0.0166 | 0.4424 | 0.4424 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.5021 | 0.5021 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0351 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.5021 | 0.5021 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0034 | 0.0461 | 0.0357 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0351 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0022 | 0.0108 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4424 | 0.4424 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0166 | 0.4424 | 0.4424 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0166 | 0.4424 | 0.4155 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0351 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0351 | 1 | 1 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0041 | 0.0664 | 0.0641 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0166 | 0.4424 | 0.4364 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.5021 | 0.5021 |
Echinococcus granulosus | enteropeptidase | 0.0034 | 0.0461 | 0.0438 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 7.05 mg | Antithrombotic effect in Wistar rat assessed as reduction in dry thrombus mass at 5 umol/L | ChEMBL. | 17827017 |
Activity (functional) | = 34.98 mg | Antithrombotic effect in Wistar rat assessed as reduction in wet thrombus mass at 5 umol/L | ChEMBL. | 17827017 |
Inhibition (functional) | = 12.09 % | Inhibition of ADP-induced platelet aggregation in rabbit platelet rich plasma at 0.1 umol/L | ChEMBL. | 17827017 |
Inhibition (functional) | = 20.54 % | Inhibition of PAF-induced platelet aggregation in rabbit platelet rich plasma at 0.1 umol/L | ChEMBL. | 17827017 |
Inhibition (functional) | = 28.2 % | Inhibition of ADP-induced platelet aggregation in rabbit platelet rich plasma at 1 umol/L | ChEMBL. | 17827017 |
Inhibition (functional) | = 36.43 % | Inhibition of PAF-induced platelet aggregation in rabbit platelet rich plasma at 1 umol/L | ChEMBL. | 17827017 |
Inhibition (functional) | = 45 % | Inhibition of ADP-induced platelet aggregation in rabbit platelet rich plasma at 10 umol/L | ChEMBL. | 17827017 |
Inhibition (functional) | = 54.93 % | Inhibition of PAF-induced platelet aggregation in rabbit platelet rich plasma at 10 umol/L | ChEMBL. | 17827017 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.