Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0009 | 0.0012 | 0.0081 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0217 | 0.4746 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0015 | 0.006 | 0.1117 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0388 | 0.168 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.006 | 0.0474 | 0.0474 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.003 | 0.0201 | 0.0201 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0566 | 0.1155 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0388 | 0.0793 |
Brugia malayi | hypothetical protein | 0.026 | 0.2311 | 1 |
Mycobacterium tuberculosis | Isocitrate lyase Icl (isocitrase) (isocitratase) | 0.0559 | 0.5044 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0038 | 0.0271 | 1 |
Brugia malayi | hypothetical protein | 0.0166 | 0.145 | 0.6276 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0012 | 0.0034 | 0.0518 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0015 | 0.006 | 0.1117 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0217 | 0.0938 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0012 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0201 | 0.0872 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.006 | 0.0474 | 0.0474 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.11 | 1 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0025 | 0.0152 | 0.0152 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0043 | 0.0317 | 0.0317 |
Echinococcus multilocularis | Chromo domain | 0.0009 | 0.0012 | 0.0012 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0038 | 0.0271 | 0.5615 |
Brugia malayi | Doublecortin family protein | 0.006 | 0.0474 | 0.2052 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0038 | 0.0271 | 0.8139 |
Echinococcus multilocularis | neuropeptide s receptor | 0.11 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0058 | 0.0253 |
Echinococcus multilocularis | GPCR, family 2 | 0.0043 | 0.0317 | 0.0317 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0009 | 0.0012 | 0.0024 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0034 | 0.0239 | 0.1647 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.003 | 0.0201 | 0.4389 |
Onchocerca volvulus | 0.003 | 0.0199 | 0.1372 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0388 | 0.0388 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0154 | 0.0668 |
Onchocerca volvulus | 0.0166 | 0.145 | 1 | |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0044 | 0.0331 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0038 | 0.0271 | 0.0271 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0015 | 0.006 | 0.1117 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.11 | 1 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.006 | 0.0474 | 0.0474 |
Brugia malayi | M-phase phosphoprotein, mpp8 | 0.0009 | 0.0012 | 0.0051 |
Onchocerca volvulus | 0.0023 | 0.014 | 0.0967 | |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0317 | 0.0647 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.0199 | 0.0407 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0012 | 0.0051 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.003 | 0.0201 | 0.5702 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.145 | 0.6276 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0011 | 0.0024 | 0.0024 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0043 | 0.0317 | 0.0317 |
Brugia malayi | intermediate filament protein | 0.003 | 0.0199 | 0.0861 |
Brugia malayi | SET domain containing protein | 0.001 | 0.0016 | 0.0071 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0009 | 0.0009 | 0.0009 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0012 | 0.0038 | 0.0599 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.001 | 0.0016 | 0.0034 |
Brugia malayi | CHD4 protein | 0.0011 | 0.0024 | 0.0104 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.003 | 0.0201 | 0.5702 |
Echinococcus granulosus | Chromobox protein 3 | 0.0009 | 0.0012 | 0.0012 |
Echinococcus granulosus | Chromo domain | 0.0009 | 0.0012 | 0.0012 |
Echinococcus multilocularis | RUN | 0.006 | 0.0474 | 0.0474 |
Echinococcus multilocularis | cpg binding protein | 0.0025 | 0.0152 | 0.0152 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.0769 | 0.157 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.1158 | 0.5013 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.002 | 0.0109 | 0.3039 |
Schistosoma mansoni | lamin | 0.003 | 0.0199 | 0.0407 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0566 | 0.1155 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0014 | 0.0058 | 0.0058 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0543 | 0.4896 | 0.4896 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0038 | 0.0271 | 0.0271 |
Brugia malayi | hypothetical protein | 0.0013 | 0.0044 | 0.0192 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.003 | 0.0201 | 0.4389 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0015 | 0.006 | 0.1117 |
Trichomonas vaginalis | chromobox protein, putative | 0.0034 | 0.0239 | 0.5254 |
Schistosoma mansoni | polycystin 1-related | 0.006 | 0.0474 | 0.0968 |
Echinococcus granulosus | chromobox protein 1 | 0.0056 | 0.0444 | 0.0444 |
Echinococcus granulosus | chromobox protein 1 | 0.0056 | 0.0444 | 0.0444 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0038 | 0.0271 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0043 | 0.0317 | 0.0317 |
Loa Loa (eye worm) | TAR-binding protein | 0.007 | 0.0566 | 0.2448 |
Schistosoma mansoni | lipoxygenase | 0.0231 | 0.2038 | 0.4163 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0011 | 0.0024 | 0.0104 |
Trichomonas vaginalis | chromobox protein, putative | 0.0056 | 0.0444 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0073 | 0.0315 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0012 | 0.0051 |
Echinococcus multilocularis | chromobox protein 2 | 0.0009 | 0.0012 | 0.0012 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0543 | 0.4896 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0015 | 0.006 | 0.1117 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 1 | 0.0009 | 0.0012 | 0.0012 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.003 | 0.0201 | 0.0411 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0201 | 0.4389 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.0199 | 0.0861 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0231 | 0.2038 | 0.2038 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0022 | 0.0132 | 0.2789 |
Echinococcus multilocularis | chromobox protein 1 | 0.0056 | 0.0444 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0474 | 0.2052 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0038 | 0.0271 | 0.0271 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0053 | 0.0413 | 0.1789 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0038 | 0.0271 | 1 |
Onchocerca volvulus | 0.0053 | 0.0413 | 0.285 | |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0413 | 0.0844 |
Echinococcus multilocularis | lamin | 0.003 | 0.0199 | 0.0199 |
Echinococcus multilocularis | musashi | 0.003 | 0.0199 | 0.0199 |
Echinococcus multilocularis | Chromobox protein 3 | 0.0009 | 0.0012 | 0.0012 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.006 | 0.0474 | 0.0474 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0566 | 0.1155 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.002 | 0.0109 | 0.2097 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.003 | 0.0201 | 0.0201 |
Brugia malayi | Associated with TFs and helicases family protein | 0.0009 | 0.0012 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0053 | 0.0231 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0022 | 0.0132 | 0.2789 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0043 | 0.0317 | 0.1371 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | RNA binding protein | 0.007 | 0.0566 | 0.2448 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0038 | 0.0599 |
Schistosoma mansoni | cpg binding protein | 0.0025 | 0.0152 | 0.0311 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0009 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0038 | 0.0271 | 0.1174 |
Schistosoma mansoni | cpg binding protein | 0.0023 | 0.014 | 0.0286 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) | 0.0559 | 0.5044 | 1 |
Schistosoma mansoni | chromobox protein | 0.0009 | 0.0012 | 0.0024 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0038 | 0.0271 | 0.0271 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0038 | 0.0271 | 0.0271 |
Onchocerca volvulus | 0.006 | 0.0474 | 0.3269 | |
Loa Loa (eye worm) | helicase | 0.0009 | 0.0012 | 0.0051 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0009 | 0.0012 | 0.0024 |
Schistosoma mansoni | loxhd1 | 0.006 | 0.0474 | 0.0968 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0388 | 0.0388 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.026 | 0.2311 | 0.2311 |
Schistosoma mansoni | chromobox protein | 0.0009 | 0.0012 | 0.0024 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0038 | 0.0271 | 1 |
Brugia malayi | chromobox protein homolog 3 | 0.0032 | 0.0217 | 0.0938 |
Brugia malayi | RNA recognition motif domain containing protein | 0.007 | 0.0566 | 0.2448 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0038 | 0.0271 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0043 | 0.0317 | 0.1371 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.003 | 0.0201 | 0.5702 |
Brugia malayi | Type III restriction enzyme, res subunit family protein | 0.0009 | 0.0012 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0012 | 0.0051 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0043 | 0.0317 | 0.1371 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0011 | 0.0024 | 0.0049 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.006 | 0.0474 | 0.0474 |
Brugia malayi | Valyl-tRNA synthetase | 0.0009 | 0.0012 | 0.0051 |
Brugia malayi | RNA binding protein | 0.007 | 0.0566 | 0.2448 |
Brugia malayi | Isocitrate dehydrogenase | 0.0038 | 0.0271 | 0.1174 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0109 | 0.0471 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0012 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0199 | 0.0861 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0011 | 0.0024 | 0.0024 |
Mycobacterium ulcerans | isocitrate lyase Icl | 0.0559 | 0.5044 | 0.5 |
Echinococcus granulosus | chromobox protein 2 | 0.0009 | 0.0012 | 0.0012 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0388 | 0.0793 |
Onchocerca volvulus | 0.003 | 0.0199 | 0.1372 | |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0009 | 0.0012 | 0.0024 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0009 | 0.0018 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0566 | 0.1155 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0388 | 0.0388 |
Mycobacterium ulcerans | isocitrate lyase AceAb | 0.0559 | 0.5044 | 0.5 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0032 | 0.0217 | 0.1495 |
Plasmodium falciparum | LCCL domain-containing protein | 0.006 | 0.0474 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0123 | 0.1054 | 0.2153 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0194 | 0.084 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0056 | 0.0444 | 0.1921 |
Onchocerca volvulus | 0.001 | 0.0016 | 0.0113 | |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0038 | 0.0271 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0769 | 0.3327 |
Echinococcus granulosus | GPCR family 2 | 0.0043 | 0.0317 | 0.0317 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.006 | 0.0474 | 0.0474 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0134 | 0.1158 | 0.5013 |
Schistosoma mansoni | survival motor neuron protein | 0.0053 | 0.0413 | 0.0844 |
Loa Loa (eye worm) | doublecortin family protein | 0.006 | 0.0474 | 0.2052 |
Brugia malayi | CXXC zinc finger family protein | 0.0023 | 0.014 | 0.0607 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.0199 | 0.0861 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0388 | 0.0793 |
Onchocerca volvulus | 0.0025 | 0.0154 | 0.1064 | |
Brugia malayi | Protein cec-1. | 0.0009 | 0.0012 | 0.0051 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0231 | 0.2038 | 0.2038 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0317 | 0.0647 |
Schistosoma mansoni | lamin | 0.003 | 0.0199 | 0.0407 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.003 | 0.0201 | 0.0201 |
Brugia malayi | TAR-binding protein | 0.007 | 0.0566 | 0.2448 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0038 | 0.0271 | 0.0554 |
Loa Loa (eye worm) | hypothetical protein | 0.026 | 0.2311 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0015 | 0.006 | 0.1117 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 1 | 0.0009 | 0.0012 | 0.0012 |
Echinococcus granulosus | RUN | 0.006 | 0.0474 | 0.0474 |
Brugia malayi | hypothetical protein | 0.006 | 0.0474 | 0.2052 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.003 | 0.0201 | 0.0201 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0015 | 0.006 | 0.1117 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0543 | 0.4896 | 0.4896 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.0199 | 0.0861 |
Echinococcus multilocularis | tar DNA binding protein | 0.007 | 0.0566 | 0.0566 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.0199 | 0.0199 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0217 | 0.4746 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0317 | 0.0647 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0012 | 0.0024 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.006 | 0.0474 | 1 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.003 | 0.0201 | 0.0872 |
Schistosoma mansoni | chromobox protein | 0.0056 | 0.0444 | 0.0907 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0053 | 0.0231 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0474 | 0.2052 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0012 | 0.0051 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0015 | 0.006 | 0.1117 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.003 | 0.0201 | 0.0201 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.003 | 0.0201 | 0.0201 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.002 | 0.0109 | 0.2097 |
Mycobacterium leprae | PROBABLE ISOCITRATE LYASE AceA (ISOCITRASE) (ISOCITRATASE) (ICL) | 0.0559 | 0.5044 | 1 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0016 | 0.0073 | 0.0315 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.003 | 0.0201 | 0.0411 |
Echinococcus multilocularis | chromobox protein 1 | 0.0056 | 0.0444 | 0.0444 |
Brugia malayi | Heterochromatin protein 1 | 0.0056 | 0.0444 | 0.1921 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) | 0.0559 | 0.5044 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0034 | 0.0239 | 0.5254 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0134 | 0.1158 | 0.5013 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.007 | 0.0566 | 0.2448 |
Schistosoma mansoni | cpg binding protein | 0.0025 | 0.0152 | 0.0311 |
Schistosoma mansoni | chromobox protein | 0.0056 | 0.0444 | 0.0907 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.002 | 0.0109 | 0.2097 |
Trichomonas vaginalis | chromobox protein, putative | 0.0056 | 0.0444 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.007 | 0.0566 | 0.0566 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0012 | 0.0051 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0014 | 0.0058 | 0.0058 |
Echinococcus granulosus | lamin | 0.003 | 0.0199 | 0.0199 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.003 | 0.0201 | 0.5702 |
Onchocerca volvulus | 0.006 | 0.0474 | 0.3269 | |
Brugia malayi | isocitrate dehydrogenase | 0.0038 | 0.0271 | 0.1174 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0012 | 0.0051 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.026 | 0.2311 | 0.2311 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.003 | 0.0201 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0388 | 0.0388 |
Brugia malayi | hypothetical protein | 0.006 | 0.0474 | 0.2052 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0038 | 0.0271 | 0.8139 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0092 | 0.0769 | 0.3327 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0317 | 0.0647 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0049 | 0.0379 | 0.0774 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.003 | 0.0201 | 1 |
Schistosoma mansoni | rab6-interacting | 0.006 | 0.0474 | 0.0968 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0388 | 0.168 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0566 | 0.1155 |
Onchocerca volvulus | 0.0009 | 0.0012 | 0.0081 | |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0038 | 0.0271 | 0.5615 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0474 | 0.0968 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0043 | 0.0317 | 0.0317 |
Schistosoma mansoni | rab6-interacting | 0.006 | 0.0474 | 0.0968 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0023 | 0.014 | 0.0607 |
Brugia malayi | hypothetical protein | 0.002 | 0.0109 | 0.0471 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0134 | 0.1158 | 0.5013 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0317 | 0.1371 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 50 nM | Antimalarial activity against Plasmodium falciparum Nigerian in human erythrocytes after 48 hrs | ChEMBL. | 18004799 |
pKa | = 11.7 | Dissociation constant, pKa of the compound by potentiometric titration | ChEMBL. | 18004799 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.