Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0339 | 0.0623 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0102 | 0.124 | 0.2276 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0079 | 0.0865 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0048 | 0.038 | 0.038 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0084 | 0.0953 | 0.1749 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0102 | 0.124 | 0.2276 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0048 | 0.038 | 0.0697 |
Loa Loa (eye worm) | acetyltransferase | 0.0146 | 0.1939 | 0.1939 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.062 | 0.062 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0184 | 0.0338 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0048 | 0.038 | 0.0697 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.0296 | 0.0543 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0048 | 0.038 | 0.038 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0193 | 0.2687 | 0.493 |
Schistosoma mansoni | coup transcription factor | 0.0102 | 0.124 | 0.2276 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0065 | 0.0641 | 0.1642 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.062 | 0.1137 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.062 | 0.1137 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0102 | 0.124 | 0.124 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0102 | 0.124 | 0.2276 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0102 | 0.124 | 0.2276 |
Schistosoma mansoni | nuclear receptor | 0.0048 | 0.038 | 0.0697 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0102 | 0.124 | 0.124 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0146 | 0.1939 | 0.1939 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0339 | 0.0623 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0146 | 0.1939 | 0.3558 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0595 | 0.9005 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0184 | 0.0338 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Brugia malayi | hypothetical protein | 0.0054 | 0.0472 | 0.0472 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0339 | 0.0339 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0595 | 0.9005 |
Brugia malayi | nuclear receptor NHR-67 | 0.0048 | 0.038 | 0.038 |
Brugia malayi | ecdysone receptor | 0.0048 | 0.038 | 0.038 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0065 | 0.0641 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0054 | 0.0472 | 0.0472 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0048 | 0.038 | 0.0697 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.0399 | 0.0731 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0048 | 0.038 | 0.0697 |
Onchocerca volvulus | 0.0048 | 0.038 | 0.185 | |
Brugia malayi | ecdysteroid receptor | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0184 | 0.0184 |
Schistosoma mansoni | nuclear receptor | 0.0048 | 0.038 | 0.0697 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0102 | 0.124 | 0.2276 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0065 | 0.0641 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0102 | 0.124 | 0.124 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0048 | 0.038 | 0.0697 |
Loa Loa (eye worm) | hypothetical protein | 0.0651 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0102 | 0.124 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.062 | 0.1137 |
Brugia malayi | tailless protein | 0.0048 | 0.038 | 0.038 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0102 | 0.124 | 0.124 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.0595 | 0.133 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.062 | 0.1137 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.0296 | 0.244 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0102 | 0.124 | 0.124 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0048 | 0.038 | 0.0697 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0048 | 0.038 | 0.038 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0065 | 0.0641 | 0.1477 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.0296 | 0.244 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0084 | 0.0953 | 0.0953 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0595 | 0.1092 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0048 | 0.038 | 0.185 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0184 | 0.0338 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0102 | 0.124 | 0.124 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0102 | 0.124 | 0.2276 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0054 | 0.0472 | 0.0472 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0102 | 0.124 | 0.2276 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0595 | 0.1092 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0102 | 0.124 | 0.124 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.0595 | 0.9005 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.0296 | 0.244 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0048 | 0.038 | 0.0697 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0065 | 0.0641 | 0.0641 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0065 | 0.0641 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0399 | 0.0399 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0339 | 0.0623 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0.0508 | 0.0508 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0142 | 0.1876 | 0.3442 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0102 | 0.124 | 0.124 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0048 | 0.038 | 0.038 |
Entamoeba histolytica | hypothetical protein | 0.0193 | 0.2687 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0102 | 0.124 | 0.2276 |
Brugia malayi | nuclear receptor RXR | 0.0048 | 0.038 | 0.038 |
Onchocerca volvulus | 0.0102 | 0.124 | 1 | |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0048 | 0.038 | 0.185 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0048 | 0.038 | 0.0697 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0054 | 0.0472 | 0.0472 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0595 | 0.9005 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0102 | 0.124 | 0.2276 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.062 | 0.062 |
Brugia malayi | nuclear receptor NHR-88 | 0.0048 | 0.038 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0472 | 0.0472 |
Schistosoma mansoni | hypothetical protein | 0.0366 | 0.5449 | 1 |
Echinococcus granulosus | geminin | 0.0366 | 0.5449 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0102 | 0.124 | 0.2276 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0184 | 0.0184 |
Schistosoma mansoni | nuclear hormone receptor | 0.0048 | 0.038 | 0.0697 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0065 | 0.0641 | 0.1175 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0065 | 0.0641 | 0.1175 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0102 | 0.124 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0339 | 0.0623 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0102 | 0.124 | 0.2276 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0472 | 0.0472 |
Brugia malayi | nuclear hormone receptor | 0.0048 | 0.038 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Schistosoma mansoni | ap endonuclease | 0.0065 | 0.0641 | 0.1175 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0065 | 0.0641 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0193 | 0.2687 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0102 | 0.124 | 0.2276 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0065 | 0.0641 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0184 | 0.0338 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.062 | 0.062 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.0595 | 0.1092 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0048 | 0.038 | 0.0697 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0048 | 0.038 | 0.0697 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0054 | 0.0472 | 0.0866 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0048 | 0.038 | 0.0697 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0048 | 0.038 | 0.038 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0048 | 0.038 | 0.0697 |
Onchocerca volvulus | 0.0049 | 0.0399 | 0.2028 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0102 | 0.124 | 0.124 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0048 | 0.038 | 0.0697 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0065 | 0.0641 | 0.5 |
Brugia malayi | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Brugia malayi | follicle stimulating hormone receptor | 0.0485 | 0.7349 | 0.7349 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0102 | 0.124 | 0.2276 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0102 | 0.124 | 0.2276 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0079 | 0.0865 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0092 | 0.1076 | 0.1975 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0102 | 0.124 | 0.2276 |
Brugia malayi | conserved hypotetical protein | 0.0048 | 0.038 | 0.038 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0184 | 0.0184 |
Brugia malayi | RNA binding protein | 0.0063 | 0.062 | 0.062 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0472 | 0.0472 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0102 | 0.124 | 0.2276 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0065 | 0.0641 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0472 | 0.0472 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0065 | 0.0641 | 0.0641 |
Brugia malayi | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0102 | 0.124 | 0.124 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.062 | 0.1137 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0065 | 0.0641 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.0337 | 0.499 | 0.9157 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0102 | 0.124 | 0.2276 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0054 | 0.0472 | 0.0866 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0048 | 0.038 | 0.0697 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.0508 | 0.0508 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0048 | 0.038 | 0.038 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0102 | 0.124 | 0.2276 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0102 | 0.124 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.0296 | 0.1636 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.0595 | 0.9005 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Schistosoma mansoni | nuclear hormone receptor | 0.0048 | 0.038 | 0.0697 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.062 | 0.1137 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.062 | 0.062 |
Brugia malayi | nuclear receptor RXR | 0.0054 | 0.0472 | 0.0472 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0776 | 0.0776 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.0224 | 0.0224 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0184 | 0.0184 |
Brugia malayi | hypothetical protein | 0.0193 | 0.2687 | 0.2687 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0184 | 0.0184 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0193 | 0.2687 | 0.493 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0054 | 0.0472 | 0.0866 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0184 | 0.0184 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0084 | 0.0953 | 0.1749 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0092 | 0.1076 | 0.1975 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0102 | 0.124 | 0.2276 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0065 | 0.0641 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0508 | 0.0508 |
Schistosoma mansoni | zinc finger protein | 0.0048 | 0.038 | 0.0697 |
Echinococcus multilocularis | geminin | 0.0366 | 0.5449 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0102 | 0.124 | 0.2276 |
Schistosoma mansoni | ap endonuclease | 0.0065 | 0.0641 | 0.1175 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0485 | 0.7349 | 0.7349 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0142 | 0.1876 | 0.3442 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0102 | 0.124 | 0.124 |
Schistosoma mansoni | thyroid hormone receptor | 0.0244 | 0.3505 | 0.6431 |
Brugia malayi | nuclear hormone receptor | 0.0102 | 0.124 | 0.124 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.0296 | 0.1636 |
Schistosoma mansoni | hypothetical protein | 0.0193 | 0.2687 | 0.493 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0102 | 0.124 | 0.124 |
Toxoplasma gondii | exonuclease III APE | 0.0065 | 0.0641 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0193 | 0.2687 | 0.493 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0244 | 0.3505 | 0.6431 |
Echinococcus granulosus | FTZ F1 alpha | 0.0102 | 0.124 | 0.2276 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0048 | 0.038 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.124 | 0.124 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0339 | 0.0623 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0065 | 0.0641 | 0.6704 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0142 | 0.1874 | 0.3438 |
Brugia malayi | nuclear receptor NHR-88 | 0.0102 | 0.124 | 0.124 |
Brugia malayi | steroid hormone receptor | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0339 | 0.0339 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0102 | 0.124 | 0.2276 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0048 | 0.038 | 0.0697 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0102 | 0.124 | 0.2276 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0472 | 0.0472 |
Brugia malayi | hypothetical protein | 0.0054 | 0.0472 | 0.0472 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0102 | 0.124 | 0.124 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0229 | 0.3273 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0224 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0048 | 0.038 | 0.038 |
Echinococcus multilocularis | tumor protein p63 | 0.0337 | 0.499 | 0.9157 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0184 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0366 | 0.5449 | 1 |
Onchocerca volvulus | 0.0048 | 0.038 | 0.185 | |
Loa Loa (eye worm) | DR-78 | 0.0048 | 0.038 | 0.038 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0065 | 0.0641 | 0.6704 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0339 | 0.0623 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0102 | 0.124 | 0.124 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.062 | 0.062 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Entamoeba histolytica | hypothetical protein | 0.0193 | 0.2687 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0184 | 0.0184 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0102 | 0.124 | 0.2276 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0084 | 0.0953 | 0.0953 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0048 | 0.038 | 0.038 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.0595 | 0.1092 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0184 | 0.0184 |
Schistosoma mansoni | thyroid hormone receptor | 0.0244 | 0.3505 | 0.6431 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0184 | 0.0184 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0102 | 0.124 | 0.2276 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0102 | 0.124 | 0.2276 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0224 | 0.0224 |
Entamoeba histolytica | hypothetical protein | 0.0193 | 0.2687 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0102 | 0.124 | 0.2276 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0339 | 0.0623 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0.0508 | 0.0508 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0065 | 0.0641 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0184 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0102 | 0.124 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.038 | 0.038 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0054 | 0.0472 | 0.0866 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0146 | 0.1939 | 0.3558 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.062 | 0.1137 |
Schistosoma mansoni | hypothetical protein | 0.0142 | 0.1876 | 0.3442 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki app (binding) | > 100 uM | Inhibition of Mycobacterium tuberculosis recombinant MbtA expressed in Escherichia coli by ATP/PPi exchange assay | ChEMBL. | 17967002 |
MIC99 (functional) | > 200 uM | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv in iron deficient GAST medium | ChEMBL. | 17967002 |
MIC99 (functional) | > 200 uM | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv in iron rich GAST medium | ChEMBL. | 17967002 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.