Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1078 | 0.1066 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0251 | 0.7039 | 0.7034 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.7039 | 0.7035 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0251 | 0.7039 | 0.7233 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.1078 | 0.1063 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0251 | 0.7039 | 0.7034 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0065 | 0.1571 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0018 | 0.0004 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0427 | 0.041 |
Brugia malayi | ecdysone receptor | 0.0118 | 0.3138 | 0.3126 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0251 | 0.7039 | 0.7034 |
Schistosoma mansoni | nuclear receptor | 0.0118 | 0.3138 | 0.3227 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.3556 | 0.3547 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0118 | 0.3138 | 0.3214 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0427 | 0.0414 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0118 | 0.3138 | 0.3227 |
Schistosoma mansoni | lamin | 0.0026 | 0.0427 | 0.044 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0021 | 0.0271 | 0.0279 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0251 | 0.7039 | 0.7238 |
Trichomonas vaginalis | AGC family protein kinase | 0.0065 | 0.1571 | 0.2427 |
Entamoeba histolytica | protein kinase 2, putative | 0.0041 | 0.085 | 0.5357 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0021 | 0.0271 | 0.0261 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0251 | 0.7039 | 0.7233 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0021 | 0.0271 | 0.0258 |
Schistosoma mansoni | coup transcription factor | 0.0251 | 0.7039 | 0.7238 |
Echinococcus multilocularis | protein kinase c iota type | 0.0021 | 0.0271 | 0.0261 |
Brugia malayi | Protein kinase domain containing protein | 0.0021 | 0.0271 | 0.0254 |
Schistosoma mansoni | nuclear hormone receptor | 0.0118 | 0.3138 | 0.3227 |
Schistosoma mansoni | thyroid hormone receptor | 0.0251 | 0.7039 | 0.7238 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0105 | 0.0092 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0118 | 0.3138 | 0.3126 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0021 | 0.0271 | 0.0261 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0427 | 0.0422 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.3138 | 0.3129 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.3138 | 0.3129 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0118 | 0.3138 | 0.3227 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0251 | 0.7039 | 0.7238 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0251 | 0.7039 | 0.7233 |
Brugia malayi | steroid hormone receptor | 0.0251 | 0.7039 | 0.7034 |
Brugia malayi | Protein kinase domain containing protein | 0.0021 | 0.0271 | 0.0254 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0105 | 0.009 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0251 | 0.7039 | 0.7034 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.3138 | 0.3129 |
Trichomonas vaginalis | AGC family protein kinase | 0.0021 | 0.0271 | 0.0396 |
Brugia malayi | tailless protein | 0.0118 | 0.3138 | 0.3126 |
Brugia malayi | nuclear hormone receptor | 0.0118 | 0.3138 | 0.3126 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0021 | 0.0271 | 0.0261 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.004 | 0.0837 | 0.0843 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0118 | 0.3138 | 0.3129 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.3138 | 0.3129 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0021 | 0.0271 | 0.0279 |
Echinococcus granulosus | nervana 2 | 0.004 | 0.0837 | 0.0843 |
Trichomonas vaginalis | AGC family protein kinase | 0.0065 | 0.1571 | 0.2427 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0015 | 0.0106 | 0.0091 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0105 | 0.0108 |
Echinococcus multilocularis | nervana 2 | 0.004 | 0.0837 | 0.0843 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0507 | 0.0504 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0017 | 0.0164 | 0.0146 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0045 | 0.0968 | 0.0979 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0628 | 0.0646 |
Trichomonas vaginalis | AGC family protein kinase | 0.0021 | 0.0271 | 0.0396 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0028 | 0.001 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0132 | 0.3556 | 0.3545 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0021 | 0.0271 | 0.0258 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0041 | 0.085 | 0.0857 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.3138 | 0.3129 |
Onchocerca volvulus | 0.0118 | 0.3138 | 0.3126 | |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0342 | 0.9726 | 1 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0342 | 0.9726 | 1 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0012 | 0.0018 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0413 | 0.04 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0069 | 0.0051 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0012 | 0.0018 | 0.0018 |
Brugia malayi | nuclear receptor NHR-88 | 0.0118 | 0.3138 | 0.3126 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0061 | 0.1453 | 0.1441 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0021 | 0.0271 | 0.0258 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0251 | 0.7039 | 0.7035 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0017 | 0.0164 | 0.0151 |
Schistosoma mansoni | lamin | 0.0026 | 0.0427 | 0.044 |
Brugia malayi | nuclear receptor NHR-88 | 0.0251 | 0.7039 | 0.7034 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0106 | 0.0091 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0507 | 0.5394 |
Echinococcus granulosus | protein kinase c iota type | 0.0021 | 0.0271 | 0.0261 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0105 | 0.009 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0251 | 0.7039 | 0.7233 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0251 | 0.7039 | 0.7034 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.004 | 0.0837 | 0.0843 |
Brugia malayi | nuclear receptor RXR | 0.0132 | 0.3556 | 0.3545 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0251 | 0.7039 | 0.7034 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0427 | 0.0422 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0017 | 0.0164 | 0.0151 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0021 | 0.0271 | 0.0261 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0628 | 0.0611 |
Schistosoma mansoni | ras GTP exchange factor | 0.0012 | 0.0018 | 0.0018 |
Giardia lamblia | Kinase, AGC PKA | 0.0041 | 0.085 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0251 | 0.7039 | 0.7035 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0251 | 0.7039 | 0.7034 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0118 | 0.3138 | 0.3214 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.3138 | 0.3129 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0132 | 0.3556 | 0.3656 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0118 | 0.3138 | 0.3214 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0041 | 0.085 | 1 |
Echinococcus granulosus | protein kinase C gamma type | 0.0021 | 0.0271 | 0.0261 |
Schistosoma mansoni | thyroid hormone receptor | 0.0251 | 0.7039 | 0.7238 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0065 | 0.1571 | 0.156 |
Echinococcus granulosus | FTZ F1 alpha | 0.0251 | 0.7039 | 0.7233 |
Brugia malayi | conserved hypotetical protein | 0.0118 | 0.3138 | 0.3126 |
Onchocerca volvulus | 0.0026 | 0.0427 | 0.041 | |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0427 | 0.0422 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0105 | 0.0092 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0507 | 0.0504 |
Schistosoma mansoni | dishevelled | 0.0017 | 0.0164 | 0.0169 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.7039 | 0.7035 |
Brugia malayi | nuclear receptor RXR | 0.0118 | 0.3138 | 0.3126 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0164 | 0.0151 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0106 | 0.5 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0105 | 0.009 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0012 | 0.0018 | 0.0004 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0045 | 0.0968 | 0.0996 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0021 | 0.0271 | 0.0279 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0628 | 0.0615 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0427 | 0.041 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.1078 | 0.1063 |
Brugia malayi | nuclear hormone receptor | 0.0251 | 0.7039 | 0.7034 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0118 | 0.3138 | 0.3214 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.3556 | 0.3547 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0105 | 0.009 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0507 | 0.0522 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0251 | 0.7039 | 0.7034 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0105 | 0.0108 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0118 | 0.3138 | 0.3214 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0021 | 0.0271 | 0.0261 |
Onchocerca volvulus | 0.0017 | 0.0164 | 0.0146 | |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0118 | 0.3138 | 0.3214 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0251 | 0.7039 | 0.7035 |
Brugia malayi | DIX domain containing protein | 0.0017 | 0.0164 | 0.0146 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0251 | 0.7039 | 0.7034 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.1137 | 0.1169 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0251 | 0.7039 | 0.7034 |
Loa Loa (eye worm) | hypothetical protein | 0.0351 | 1 | 1 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0045 | 0.0968 | 0.6119 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.7039 | 0.7035 |
Loa Loa (eye worm) | DR-78 | 0.0118 | 0.3138 | 0.3129 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0251 | 0.7039 | 0.7233 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0118 | 0.3138 | 0.3126 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0118 | 0.3138 | 0.3214 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0251 | 0.7039 | 0.7238 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0021 | 0.0271 | 0.0258 |
Onchocerca volvulus | 0.0118 | 0.3138 | 0.3126 | |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0507 | 0.0504 |
Schistosoma mansoni | nuclear receptor | 0.0118 | 0.3138 | 0.3227 |
Toxoplasma gondii | AGC kinase | 0.0061 | 0.1453 | 1 |
Brugia malayi | hypothetical protein | 0.0132 | 0.3556 | 0.3545 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0476 | 0.0472 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0015 | 0.0106 | 0.5 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0118 | 0.3138 | 0.3126 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0021 | 0.0271 | 0.0261 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0045 | 0.0968 | 1 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0017 | 0.0164 | 0.0151 |
Entamoeba histolytica | protein kinase, putative | 0.0065 | 0.1571 | 1 |
Trypanosoma cruzi | Protein kinase B | 0.0045 | 0.0968 | 1 |
Echinococcus multilocularis | nervana 2 | 0.004 | 0.0837 | 0.0843 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0507 | 0.0522 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.3127 | 0.3118 |
Trichomonas vaginalis | AGC family protein kinase | 0.0065 | 0.1571 | 0.2427 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0012 | 0.0018 | 0.0018 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0017 | 0.0164 | 0.0169 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0251 | 0.7039 | 0.7238 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.3138 | 0.3129 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0132 | 0.3556 | 0.3645 |
Onchocerca volvulus | 0.0029 | 0.0507 | 0.049 | |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0105 | 0.0108 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0017 | 0.0164 | 0.0169 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0164 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.3556 | 0.3547 |
Echinococcus granulosus | nervana 2 | 0.004 | 0.0837 | 0.0843 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0021 | 0.0271 | 0.0279 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0251 | 0.7039 | 0.7233 |
Schistosoma mansoni | dep domain containing protein | 0.0017 | 0.0164 | 0.0169 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.3138 | 0.3129 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.7039 | 0.7035 |
Trichomonas vaginalis | set domain proteins, putative | 0.0229 | 0.6419 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0251 | 0.7039 | 0.7238 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0427 | 0.044 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0251 | 0.7039 | 0.7238 |
Toxoplasma gondii | hypothetical protein | 0.0017 | 0.0164 | 0.043 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0041 | 0.085 | 0.0857 |
Schistosoma mansoni | regulator of G protein signaling | 0.0017 | 0.0164 | 0.0169 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0251 | 0.7039 | 0.7034 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0017 | 0.0164 | 0.0151 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0251 | 0.7039 | 0.7238 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0015 | 0.0106 | 0.0928 |
Onchocerca volvulus | 0.0026 | 0.0427 | 0.041 | |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0118 | 0.3138 | 0.3227 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0251 | 0.7039 | 0.7233 |
Trichomonas vaginalis | AGC family protein kinase | 0.0065 | 0.1571 | 0.2427 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0251 | 0.7039 | 0.7034 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.7039 | 0.7035 |
Brugia malayi | protein kinase C II. | 0.0021 | 0.0271 | 0.0254 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0507 | 0.049 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0507 | 0.0522 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0028 | 0.0014 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0017 | 0.0164 | 0.0151 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0507 | 0.0522 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0017 | 0.0164 | 0.0151 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0017 | 0.0164 | 0.0151 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0342 | 0.9726 | 0.9726 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0105 | 0.009 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0251 | 0.7039 | 0.7233 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.3138 | 0.3129 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0251 | 0.7039 | 0.7233 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0105 | 0.009 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0427 | 0.0414 |
Brugia malayi | Isocitrate dehydrogenase | 0.0015 | 0.0106 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.7039 | 0.7035 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0251 | 0.7039 | 0.7233 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0118 | 0.3138 | 0.3129 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0251 | 0.7039 | 0.7035 |
Trichomonas vaginalis | serine/threonine-protein kinase sgk, putative | 0.002 | 0.0258 | 0.0375 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0251 | 0.7039 | 0.7035 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0164 | 0.0146 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0342 | 0.9726 | 0.9726 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0251 | 0.7039 | 0.7034 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0202 | 0.5598 | 0.5592 |
Schistosoma mansoni | hypothetical protein | 0.0331 | 0.9423 | 0.9688 |
Brugia malayi | Pre-SET motif family protein | 0.0202 | 0.5598 | 0.559 |
Trichomonas vaginalis | AGC family protein kinase | 0.0025 | 0.0389 | 0.058 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0018 | 0.0004 |
Echinococcus granulosus | lamin | 0.0026 | 0.0427 | 0.0422 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0021 | 0.0271 | 0.0261 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0106 | 0.0091 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0105 | 0.0108 |
Schistosoma mansoni | serine/threonine kinase | 0.0021 | 0.0271 | 0.0279 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0251 | 0.7039 | 0.7238 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0251 | 0.7039 | 0.7035 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0251 | 0.7039 | 0.7233 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0427 | 0.0414 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.3138 | 0.3129 |
Brugia malayi | Protein kinase domain containing protein | 0.0065 | 0.1571 | 0.1556 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0251 | 0.7039 | 0.7034 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0251 | 0.7039 | 0.7034 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.004 | 0.0837 | 0.0843 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0251 | 0.7039 | 0.7034 |
Schistosoma mansoni | nuclear hormone receptor | 0.0118 | 0.3138 | 0.3227 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0118 | 0.3138 | 0.3129 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0021 | 0.0271 | 0.0261 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0118 | 0.3138 | 0.3214 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.7039 | 0.7035 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0427 | 0.0422 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0015 | 0.0106 | 0.0093 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0118 | 0.3138 | 0.3214 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.1078 | 0.1066 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0251 | 0.7039 | 0.7035 |
Echinococcus granulosus | geminin | 0.0331 | 0.9423 | 0.9687 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0015 | 0.0106 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0271 | 0.0258 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0342 | 0.9726 | 1 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0028 | 0.001 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.004 | 0.0837 | 0.0843 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0041 | 0.085 | 0.8755 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0021 | 0.0271 | 0.0258 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0132 | 0.3556 | 0.3545 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0251 | 0.7039 | 0.7034 |
Onchocerca volvulus | 0.0251 | 0.7039 | 0.7034 | |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0021 | 0.0271 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.3556 | 0.3547 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0045 | 0.0968 | 0.0979 |
Schistosoma mansoni | dishevelled | 0.0017 | 0.0164 | 0.0169 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0021 | 0.0271 | 0.0258 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0118 | 0.3138 | 0.3126 |
Schistosoma mansoni | hypothetical protein | 0.0331 | 0.9423 | 0.9688 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0251 | 0.7039 | 0.7233 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0106 | 0.0091 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0106 | 0.0928 |
Schistosoma mansoni | guanine-nucleotide-exchange-factor | 0.0012 | 0.0018 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.3138 | 0.3129 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0012 | 0.0018 | 0.0018 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0021 | 0.0271 | 0.0261 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0017 | 0.0164 | 0.0151 |
Schistosoma mansoni | zinc finger protein | 0.0118 | 0.3138 | 0.3227 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0118 | 0.3138 | 0.3126 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0017 | 0.0164 | 0.0151 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0017 | 0.0164 | 0.0151 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0041 | 0.085 | 0.0857 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0017 | 0.0164 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.7039 | 0.7035 |
Brugia malayi | hypothetical protein | 0.0118 | 0.3138 | 0.3126 |
Brugia malayi | isocitrate dehydrogenase | 0.0015 | 0.0106 | 0.0088 |
Trichomonas vaginalis | AGC family protein kinase | 0.0065 | 0.1571 | 0.2427 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0118 | 0.3138 | 0.3214 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0015 | 0.0106 | 0.0091 |
Entamoeba histolytica | protein kinase, putative | 0.0021 | 0.0271 | 0.163 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0251 | 0.7039 | 0.7233 |
Onchocerca volvulus | 0.0229 | 0.6419 | 0.6413 | |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0118 | 0.3138 | 0.3214 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0045 | 0.0968 | 0.6119 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0061 | 0.1453 | 0.1438 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0106 | 0.0091 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0507 | 0.298 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0251 | 0.7039 | 0.7238 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.3138 | 0.3129 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0045 | 0.0968 | 0.0996 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0351 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0251 | 0.7039 | 0.7233 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0017 | 0.0164 | 0.0151 |
Entamoeba histolytica | protein kinase, putative | 0.0061 | 0.1453 | 0.9238 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0017 | 0.0164 | 0.0151 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0251 | 0.7039 | 0.7034 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0132 | 0.3556 | 0.3547 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0021 | 0.0271 | 0.0261 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0251 | 0.7039 | 0.7233 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0251 | 0.7039 | 0.7035 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0105 | 0.0088 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0021 | 0.0271 | 0.0279 |
Trichomonas vaginalis | AGC family protein kinase | 0.0021 | 0.0271 | 0.0396 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0251 | 0.7039 | 0.7238 |
Trichomonas vaginalis | AGC family protein kinase | 0.0065 | 0.1571 | 0.2427 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0021 | 0.0271 | 0.0279 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0251 | 0.7039 | 0.7034 |
Schistosoma mansoni | atypical protein kinase C | 0.0021 | 0.0271 | 0.0279 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0012 | 0.0018 | 0.0004 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0118 | 0.3138 | 0.3126 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.3127 | 0.3118 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0164 | 0.0146 |
Brugia malayi | hypothetical protein | 0.0132 | 0.3556 | 0.3545 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0021 | 0.0271 | 0.0279 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0132 | 0.3556 | 0.3645 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.3556 | 0.3547 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0118 | 0.3138 | 0.3126 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0017 | 0.0164 | 0.0146 |
Echinococcus granulosus | NDR protein kinase | 0.0021 | 0.0271 | 0.0261 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0017 | 0.0164 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0507 | 0.0494 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0164 | 0.0151 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0041 | 0.085 | 1 |
Brugia malayi | hypothetical protein | 0.0118 | 0.3138 | 0.3126 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0251 | 0.7039 | 0.7233 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.3138 | 0.3129 |
Echinococcus multilocularis | geminin | 0.0331 | 0.9423 | 0.9687 |
Brugia malayi | Hr1 repeat family protein | 0.0021 | 0.0271 | 0.0254 |
Brugia malayi | ecdysteroid receptor | 0.0251 | 0.7039 | 0.7034 |
Trichomonas vaginalis | AGC family protein kinase | 0.0065 | 0.1571 | 0.2427 |
Brugia malayi | nuclear receptor NHR-67 | 0.0118 | 0.3138 | 0.3126 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0069 | 0.0055 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.3127 | 0.3115 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0021 | 0.0271 | 0.0261 |
Entamoeba histolytica | protein kinase, putative | 0.0065 | 0.1571 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0118 | 0.3138 | 0.3214 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0105 | 0.0088 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0021 | 0.0271 | 0.0261 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0132 | 0.3556 | 0.3656 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0021 | 0.0271 | 0.0261 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0118 | 0.3138 | 0.3126 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0251 | 0.7039 | 0.7233 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0021 | 0.0271 | 0.0261 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0427 | 0.0422 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | 0 | Displacement of [3H]clonidine from I1-imidazoline binding site in bovine adrenal medulla plasma membrane upto 100 uM | ChEMBL. | 17583514 |
Activity (binding) | 0 | Displacement of [3H]idazoxan from I2-imidazoline binding site in rabbit kidney membrane upto 100 uM | ChEMBL. | 17583514 |
Activity (binding) | 0 | Displacement of [3H]clonidine from alpha2-AR in cerebral cortex of rat brain upto 100 uM | ChEMBL. | 17583514 |
Activity (functional) | = 15.1 pg/microg/hr | Effect on glucose-dependent insulin secretion activity per ug of total protein in rat RIN5F cells at 0.1 uM after 30 mins | ChEMBL. | 17583514 |
Activity (functional) | = 15.9 pg/microg/hr | Effect on glucose-dependent insulin secretion activity per ug of total protein in rat RIN5F cells at 1 uM after 30 mins | ChEMBL. | 17583514 |
Activity (functional) | = 16.8 pg/microg/hr | Effect on glucose-dependent insulin secretion activity per ug of total protein in rat RIN5F cells at 10 uM after 30 mins | ChEMBL. | 17583514 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.