Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | carboxylesterase 5A | 0.0082 | 0.0169 | 0.0169 |
Brugia malayi | Protein kinase domain containing protein | 0.0163 | 0.0372 | 0.0372 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0052 | 0.0094 | 0.2403 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.0052 | 0.0045 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0052 | 1 |
Echinococcus multilocularis | Excitatory amino acid transporter | 0.4001 | 1 | 1 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.0052 | 0.0045 |
Schistosoma mansoni | neprilysin | 0.0119 | 0.0262 | 0.0262 |
Echinococcus multilocularis | neutral amino acid transporter excitatory amino acid transporter | 0.1774 | 0.4412 | 0.4412 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Mycobacterium ulcerans | hypothetical protein | 0.0065 | 0.0126 | 0.1087 |
Brugia malayi | Telomerase reverse transcriptase | 0.0139 | 0.0312 | 0.0312 |
Mycobacterium tuberculosis | Probable C4-dicarboxylate-transport transmembrane protein DctA | 0.4001 | 1 | 1 |
Onchocerca volvulus | Telomerase reverse transcriptase homolog | 0.0191 | 0.0442 | 0.0393 |
Schistosoma mansoni | hypothetical protein | 0.0119 | 0.0262 | 0.0262 |
Schistosoma mansoni | hypothetical protein | 0.0119 | 0.0262 | 0.0262 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0017 | 0.0006 | 0.0006 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0065 | 0.0126 | 0.0126 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0052 | 0.0045 |
Echinococcus multilocularis | neutral amino acid transporter A | 0.4001 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.0829 | 0.0829 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0337 | 0.0809 | 0.0809 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0126 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0052 | 0.0051 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0052 | 0.0411 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0163 | 0.0372 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0456 | 0.1108 | 0.1107 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0052 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0456 | 0.1108 | 0.1107 |
Echinococcus multilocularis | sodium:dicarboxylate symporter | 0.4001 | 1 | 1 |
Schistosoma mansoni | Nep2 peptidase (M13 family) | 0.023 | 0.0541 | 0.0541 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0049 | 0.0087 | 0.2213 |
Brugia malayi | peptidase family M13 containing protein | 0.0111 | 0.0242 | 0.0242 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.0829 | 0.0829 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0065 | 0.0126 | 0.0126 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0052 | 0.0411 |
Echinococcus multilocularis | acetylcholinesterase | 0.0082 | 0.0169 | 0.0169 |
Loa Loa (eye worm) | hypothetical protein | 0.0456 | 0.1108 | 0.1107 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0163 | 0.0372 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Onchocerca volvulus | 0.0242 | 0.0571 | 0.0522 | |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0049 | 0.0087 | 0.2213 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.0052 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0052 | 0.0051 |
Schistosoma mansoni | hypothetical protein | 0.0119 | 0.0262 | 0.0262 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0017 | 0.0006 | 0.0006 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0052 | 0.1236 |
Echinococcus granulosus | neutral amino acid transporter A | 0.4001 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0119 | 0.0262 | 0.0262 |
Loa Loa (eye worm) | carboxylesterase | 0.0082 | 0.0169 | 0.0168 |
Brugia malayi | Thioredoxin reductase | 0.0049 | 0.0087 | 0.0087 |
Echinococcus multilocularis | Mastin | 0.0065 | 0.0126 | 0.0126 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0052 | 0.5145 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0065 | 0.0126 | 0.0126 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0126 | 0.0126 |
Brugia malayi | Carboxylesterase family protein | 0.0082 | 0.0169 | 0.0169 |
Echinococcus granulosus | acetylcholinesterase | 0.0082 | 0.0169 | 0.0169 |
Schistosoma mansoni | hypothetical protein | 0.0119 | 0.0262 | 0.0262 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0082 | 0.0169 | 0.0169 |
Echinococcus multilocularis | excitatory amino acid transporter 3 | 0.4001 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0052 | 0.1236 |
Echinococcus multilocularis | enteropeptidase | 0.0065 | 0.0126 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0337 | 0.0809 | 0.0809 |
Echinococcus multilocularis | neutral amino acid transporter A | 0.4001 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Echinococcus granulosus | excitatory amino acid transporter 3 | 0.4001 | 1 | 1 |
Leishmania major | trypanothione reductase | 0.0049 | 0.0087 | 0.2213 |
Onchocerca volvulus | 0.0065 | 0.0126 | 0.0075 | |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0052 | 0.0051 |
Leishmania major | hypothetical protein, conserved | 0.0163 | 0.0372 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.0378 | 0.0378 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0111 | 0.0242 | 0.0242 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0052 | 0.0052 |
Toxoplasma gondii | thioredoxin reductase | 0.0049 | 0.0087 | 0.0735 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0456 | 0.1108 | 0.1108 |
Giardia lamblia | Telomerase catalytic subunit | 0.0052 | 0.0094 | 1 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0065 | 0.0126 | 0.0126 |
Echinococcus granulosus | neutral amino acid transporter | 0.4001 | 1 | 1 |
Brugia malayi | glutathione reductase | 0.0049 | 0.0087 | 0.0087 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0052 | 0.0052 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0456 | 0.1108 | 1 |
Schistosoma mansoni | neprilysin-2 (M13 family) | 0.023 | 0.0541 | 0.0541 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.0378 | 0.0378 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Onchocerca volvulus | 0.0065 | 0.0126 | 0.0075 | |
Plasmodium falciparum | telomerase reverse transcriptase | 0.0052 | 0.0094 | 0.2403 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0082 | 0.0169 | 0.0169 |
Brugia malayi | Trypsin family protein | 0.0065 | 0.0126 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.0829 | 0.0829 |
Onchocerca volvulus | 0.0065 | 0.0126 | 0.0075 | |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.0052 | 0.0094 | 0.2403 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0052 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0052 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0126 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0052 | 0.0051 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0052 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.0052 | 0.0045 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0163 | 0.0372 | 1 |
Loa Loa (eye worm) | excitatory amino acid transporter | 0.4001 | 1 | 1 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.023 | 0.0541 | 0.0541 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0052 | 0.0411 |
Leishmania major | telomerase reverse transcriptase, putative | 0.0052 | 0.0094 | 0.2403 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.0571 | 0.057 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0169 | 0.0168 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0052 | 0.0411 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0052 | 0.0411 |
Brugia malayi | Trypsin family protein | 0.0242 | 0.0571 | 0.0571 |
Echinococcus granulosus | Mastin | 0.0065 | 0.0126 | 0.0126 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0065 | 0.0126 | 0.0126 |
Echinococcus multilocularis | sodium:dicarboxylate symporter | 0.1774 | 0.4412 | 0.4412 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0049 | 0.0087 | 0.0087 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0242 | 0.0571 | 0.0571 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.0052 | 0.0094 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0456 | 0.1108 | 0.1108 |
Loa Loa (eye worm) | glutathione reductase | 0.0049 | 0.0087 | 0.0087 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.023 | 0.0541 | 0.0541 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0052 | 0.0052 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0075 | 0.0151 | 0.0151 |
Onchocerca volvulus | 0.0065 | 0.0126 | 0.0075 | |
Echinococcus granulosus | Excitatory amino acid transporter | 0.4001 | 1 | 1 |
Treponema pallidum | glutamate/aspartate transporter | 0.1774 | 0.4412 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.0829 | 0.0829 |
Schistosoma mansoni | hypothetical protein | 0.0163 | 0.0372 | 0.0372 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0052 | 0.0045 |
Toxoplasma gondii | kringle domain-containing protein | 0.0163 | 0.0372 | 0.3321 |
Treponema pallidum | glutamate transporter | 0.1774 | 0.4412 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0169 | 0.0168 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.0052 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.0372 | 0.0372 |
Echinococcus multilocularis | acetylcholinesterase | 0.0082 | 0.0169 | 0.0169 |
Loa Loa (eye worm) | hypothetical protein | 0.0337 | 0.0809 | 0.0809 |
Onchocerca volvulus | 0.0177 | 0.0408 | 0.0358 | |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0225 | 0.0527 | 0.0521 |
Echinococcus granulosus | Excitatory amino acid transporter | 0.4001 | 1 | 1 |
Brugia malayi | Peptidase family M13 containing protein | 0.0456 | 0.1108 | 0.1108 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.0052 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.0829 | 0.0829 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0242 | 0.0571 | 0.0571 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0049 | 0.0087 | 0.0081 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0052 | 1 |
Wolbachia endosymbiont of Brugia malayi | Na+/H+-dicarboxylate symporter | 0.4001 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.0829 | 0.0829 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0052 | 0.1236 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0052 | 0.0052 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0052 | 0.1236 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0126 | 0.0126 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0111 | 0.0242 | 0.0242 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0052 | 0.0052 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0065 | 0.0126 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0052 | 0.0051 |
Schistosoma mansoni | solute carrier family 1 (glial high affinity glutamate transporter | 0.4001 | 1 | 1 |
Schistosoma mansoni | sodium/dicarboxylate symporter-related | 0.1774 | 0.4412 | 0.4412 |
Echinococcus granulosus | excitatory amino acid transporter 2 | 0.4001 | 1 | 1 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0017 | 0.0006 | 0.0006 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0111 | 0.0242 | 0.0242 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0052 | 0.0052 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.0052 | 0.0094 | 0.0798 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.0571 | 0.057 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0049 | 0.0087 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0337 | 0.0809 | 0.0809 |
Echinococcus multilocularis | excitatory amino acid transporter 2 | 0.4001 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0082 | 0.0169 | 0.0168 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0075 | 0.0151 | 0.0151 |
Trypanosoma brucei | trypanothione reductase | 0.0049 | 0.0087 | 0.9209 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0163 | 0.0372 | 0.0372 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0052 | 0.0051 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Echinococcus granulosus | excitatory amino acid transporter 2 | 0.4001 | 1 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0119 | 0.0262 | 0.0262 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0126 | 0.0126 |
Onchocerca volvulus | 0.0065 | 0.0126 | 0.0075 | |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0052 | 0.0051 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0065 | 0.0126 | 0.0126 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Echinococcus multilocularis | neutral amino acid transporter A | 0.4001 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0065 | 0.0126 | 0.0126 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.0052 | 0.0045 |
Chlamydia trachomatis | neutral amino acid transporter | 0.1774 | 0.4412 | 0.4408 |
Echinococcus granulosus | enteropeptidase | 0.0065 | 0.0126 | 0.0126 |
Brugia malayi | Kringle domain containing protein | 0.0163 | 0.0372 | 0.0372 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0052 | 1 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0052 | 0.0094 | 0.2403 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0052 | 1 |
Onchocerca volvulus | Excitatory amino acid transporter homolog | 0.4001 | 1 | 1 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0337 | 0.0809 | 0.0809 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0052 | 1 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0163 | 0.0372 | 0.0372 |
Schistosoma mansoni | sodium/dicarboxylate symporter-related | 0.1774 | 0.4412 | 0.4412 |
Echinococcus multilocularis | neutral amino acid transporter excitatory amino acid transporter | 0.4001 | 1 | 1 |
Loa Loa (eye worm) | trypsin family protein | 0.0065 | 0.0126 | 0.0126 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0017 | 0.0006 | 0.0006 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0456 | 0.1108 | 0.1108 |
Loa Loa (eye worm) | zinc metallopeptidase 4 | 0.0111 | 0.0242 | 0.0242 |
Toxoplasma gondii | peptidase family M13 protein | 0.0456 | 0.1108 | 1 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0456 | 0.1108 | 0.1108 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0163 | 0.0372 | 0.0372 |
Loa Loa (eye worm) | hypothetical protein | 0.0226 | 0.053 | 0.053 |
Brugia malayi | Trypsin family protein | 0.0065 | 0.0126 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0126 | 0.0126 |
Echinococcus granulosus | neutral amino acid transporter A | 0.4001 | 1 | 1 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0049 | 0.0087 | 0.0087 |
Brugia malayi | Carboxylesterase family protein | 0.0082 | 0.0169 | 0.0169 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0065 | 0.0126 | 0.0126 |
Schistosoma mansoni | endothelin-converting enzyme-related | 0.0111 | 0.0242 | 0.0242 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0052 | 0.0411 |
Chlamydia trachomatis | glutamate symporter | 0.4001 | 1 | 1 |
Echinococcus granulosus | sodium:dicarboxylate symporter | 0.4001 | 1 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.023 | 0.0541 | 0.0541 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Echinococcus multilocularis | excitatory amino acid transporter 2 | 0.4001 | 1 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0111 | 0.0242 | 0.0242 |
Loa Loa (eye worm) | hypothetical protein | 0.0337 | 0.0809 | 0.0809 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0052 | 0.0052 |
Onchocerca volvulus | 0.0226 | 0.053 | 0.0481 | |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0052 | 0.0411 |
Echinococcus multilocularis | Excitatory amino acid transporter | 0.4001 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0119 | 0.0262 | 0.0262 |
Onchocerca volvulus | 0.0163 | 0.0372 | 0.0322 | |
Echinococcus granulosus | geminin | 0.0165 | 0.0378 | 0.0378 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0456 | 0.1108 | 1 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0456 | 0.1108 | 0.1102 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0126 | 0.0126 |
Plasmodium falciparum | glutathione reductase | 0.0049 | 0.0087 | 0.2213 |
Echinococcus multilocularis | geminin | 0.0165 | 0.0378 | 0.0378 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0065 | 0.0126 | 0.0126 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0065 | 0.0126 | 0.0126 |
Plasmodium vivax | glutathione reductase, putative | 0.0049 | 0.0087 | 0.2213 |
Plasmodium falciparum | thioredoxin reductase | 0.0049 | 0.0087 | 0.2213 |
Echinococcus granulosus | acetylcholinesterase | 0.0082 | 0.0169 | 0.0169 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0065 | 0.0126 | 0.0126 |
Schistosoma mansoni | endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) | 0.0111 | 0.0242 | 0.0242 |
Brugia malayi | Trypsin family protein | 0.0065 | 0.0126 | 0.0126 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Drug uptake (ADMET) | = 28.7 % | Biodistribution in Wistar rat bile assessed as drug elimination at 15 umol/kg, iv after 1 hr | ChEMBL. | 17985860 |
Drug uptake (ADMET) | = 75.1 % | Biodistribution in Wistar rat bile assessed as drug elimination at 15 umol/kg, iv after 5 hrs | ChEMBL. | 17985860 |
Drug uptake (ADMET) | = 0.3 %ID | Biodistribution in Wistar rat plasma per mL at 15 umol/kg, iv after 5 hrs | ChEMBL. | 17985860 |
Drug uptake (ADMET) | = 4.9 %ID | Biodistribution in Wistar rat urine at 15 umol/kg, iv after 5 hrs | ChEMBL. | 17985860 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.