Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0276 | 0.0913 | 0.0913 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0038 | 0.0104 | 0.011 |
Echinococcus multilocularis | cathepsin L | 0.0009 | 0.0005 | 0.0005 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0276 | 0.0913 | 0.0961 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0276 | 0.0913 | 0.0913 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0276 | 0.0913 | 0.1925 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0234 | 0.077 | 0.077 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0276 | 0.0913 | 0.1925 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.013 | 0.0418 | 0.0418 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0006 | 0.0006 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0032 | 0.0058 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0032 | 0.0034 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0032 | 0.0058 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0032 | 0.0032 |
Echinococcus granulosus | dnaJ subfamily B | 0.0404 | 0.1349 | 0.1349 |
Onchocerca volvulus | 0.0276 | 0.0913 | 0.1728 | |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0065 | 0.0198 | 0.0198 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0276 | 0.0913 | 0.0913 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0065 | 0.0198 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0017 | 0.0032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.0913 | 0.1923 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0418 | 0.0874 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0276 | 0.0913 | 0.0913 |
Brugia malayi | nuclear hormone receptor | 0.1398 | 0.4725 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.077 | 0.1618 |
Onchocerca volvulus | 0.0438 | 0.1462 | 0.2783 | |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0276 | 0.0913 | 0.1925 |
Brugia malayi | follicle stimulating hormone receptor | 0.0229 | 0.0753 | 0.1585 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.1544 | 0.522 | 1 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0404 | 0.1349 | 0.1419 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0005 | 0.0001 |
Brugia malayi | Cathepsin L-like precursor | 0.0011 | 0.0014 | 0.0018 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0276 | 0.0913 | 0.1925 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0276 | 0.0913 | 0.1925 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.013 | 0.0418 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.0913 | 0.1923 |
Schistosoma mansoni | thyroid hormone receptor | 0.0276 | 0.0913 | 0.0913 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0276 | 0.0913 | 0.1925 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0418 | 0.0874 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.013 | 0.0418 | 0.0875 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0276 | 0.0913 | 0.1925 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0072 | 0.0072 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0276 | 0.0913 | 0.1923 |
Brugia malayi | hypothetical protein | 0.013 | 0.0418 | 0.0875 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0198 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0276 | 0.0913 | 0.0961 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0017 | 0.0032 | 0.1415 |
Brugia malayi | ecdysteroid receptor | 0.0276 | 0.0913 | 0.1925 |
Onchocerca volvulus | 0.0048 | 0.0138 | 0.0239 | |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0078 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1462 | 0.3087 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0032 | 0.1415 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1462 | 0.3087 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0276 | 0.0913 | 0.1925 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.019 | 0.9614 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.013 | 0.0418 | 0.0418 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0276 | 0.0913 | 0.1925 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.013 | 0.0418 | 0.0777 |
Schistosoma mansoni | hypothetical protein | 0.0404 | 0.1349 | 0.1349 |
Brugia malayi | ecdysone receptor | 0.013 | 0.0418 | 0.0875 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0017 | 0.0032 | 0.0032 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.019 | 0.9614 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0471 | 0.0986 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0276 | 0.0913 | 0.1925 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0276 | 0.0913 | 0.1728 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0146 | 0.0471 | 0.0471 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0065 | 0.0198 | 0.0208 |
Brugia malayi | Nuclear hormone receptor E75 | 0.013 | 0.0418 | 0.0875 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0418 | 0.0874 |
Schistosoma mansoni | coup transcription factor | 0.0276 | 0.0913 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0418 | 0.0874 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0065 | 0.0198 | 0.0408 |
Brugia malayi | steroid hormone receptor | 0.0276 | 0.0913 | 0.1925 |
Schistosoma mansoni | nuclear hormone receptor | 0.013 | 0.0418 | 0.0418 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.0138 | 0.0138 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0009 | 0.0005 | 0.0005 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0058 | 0.0172 | 0.8649 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.2806 | 0.9505 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0418 | 0.0874 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0276 | 0.0913 | 0.1923 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0032 | 0.0058 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.019 | 0.955 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.019 | 0.9614 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.013 | 0.0418 | 0.044 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0234 | 0.077 | 0.081 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0276 | 0.0913 | 0.1923 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0011 | 0.0014 | 0.3182 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0276 | 0.0913 | 0.0913 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0471 | 0.0986 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0276 | 0.0913 | 0.0961 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.019 | 0.9614 |
Brugia malayi | nuclear hormone receptor | 0.0276 | 0.0913 | 0.1925 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0017 | 0.0032 | 0.0056 |
Brugia malayi | hypothetical protein | 0.0234 | 0.077 | 0.162 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.0198 | 0.0406 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0276 | 0.0913 | 0.1923 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0032 | 0.1415 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0032 | 0.0058 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0276 | 0.0913 | 0.1923 |
Echinococcus granulosus | cysteine protease | 0.0009 | 0.0005 | 0.0005 |
Brugia malayi | hypothetical protein | 0.0146 | 0.0471 | 0.0988 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.013 | 0.0418 | 0.0777 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0471 | 0.0986 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0011 | 0.0014 | 0.0018 |
Brugia malayi | hypothetical protein | 0.0146 | 0.0471 | 0.0988 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.013 | 0.0418 | 0.0874 |
Brugia malayi | nuclear receptor NHR-88 | 0.013 | 0.0418 | 0.0875 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.019 | 0.9614 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0014 | 0.0017 |
Echinococcus granulosus | FTZ F1 alpha | 0.0276 | 0.0913 | 0.0913 |
Brugia malayi | hypothetical protein | 0.0438 | 0.1462 | 0.3088 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.013 | 0.0418 | 0.044 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0276 | 0.0913 | 0.0913 |
Brugia malayi | nuclear receptor RXR | 0.013 | 0.0418 | 0.0875 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0038 | 0.0104 | 0.0104 |
Echinococcus granulosus | cathepsin L | 0.0009 | 0.0005 | 0.0005 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0017 | 0.0032 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0011 | 0.0014 | 0.3182 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0032 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.0913 | 0.1923 |
Echinococcus granulosus | cathepsin l1 | 0.0011 | 0.0014 | 0.0014 |
Schistosoma mansoni | nuclear receptor | 0.013 | 0.0418 | 0.0418 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0229 | 0.0753 | 0.1584 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0418 | 0.0874 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.019 | 0.9614 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0011 | 0.0014 | 0.0014 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.013 | 0.0418 | 0.0418 |
Brugia malayi | tailless protein | 0.013 | 0.0418 | 0.0875 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0276 | 0.0913 | 0.1925 |
Brugia malayi | Nuclear hormone receptor E75 | 0.013 | 0.0418 | 0.0875 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0063 | 0.019 | 0.9614 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0276 | 0.0913 | 0.0961 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.019 | 0.9614 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.019 | 0.9614 |
Brugia malayi | nuclear receptor NHR-88 | 0.0276 | 0.0913 | 0.1925 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0276 | 0.0913 | 0.1923 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0276 | 0.0913 | 0.1925 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.005 | 0.0144 | 0.7234 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.019 | 0.955 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0276 | 0.0913 | 0.0913 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0017 | 0.0032 | 0.0056 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.0198 | 0.0198 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0032 | 0.0036 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.013 | 0.0418 | 0.0418 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0146 | 0.0471 | 0.0496 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.013 | 0.0418 | 0.0418 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0198 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0276 | 0.0913 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0014 | 0.0017 |
Brugia malayi | cathepsin L-like precursor | 0.0011 | 0.0014 | 0.0018 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0276 | 0.0913 | 0.0913 |
Schistosoma mansoni | thyroid hormone receptor | 0.0276 | 0.0913 | 0.0913 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0032 | 1 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0032 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0276 | 0.0913 | 0.1925 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0276 | 0.0913 | 0.0913 |
Brugia malayi | conserved hypotetical protein | 0.013 | 0.0418 | 0.0875 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0418 | 0.0874 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.013 | 0.0418 | 0.044 |
Onchocerca volvulus | 0.0017 | 0.0032 | 0.0036 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Onchocerca volvulus | 0.013 | 0.0418 | 0.0777 | |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0418 | 0.0874 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0014 | 0.0017 |
Loa Loa (eye worm) | DR-78 | 0.013 | 0.0418 | 0.0874 |
Onchocerca volvulus | 0.0028 | 0.0072 | 0.0113 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Schistosoma mansoni | zinc finger protein | 0.013 | 0.0418 | 0.0418 |
Brugia malayi | hypothetical protein | 0.013 | 0.0418 | 0.0875 |
Loa Loa (eye worm) | cysteine protease | 0.0017 | 0.0032 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0418 | 0.0874 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0276 | 0.0913 | 0.0961 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0032 | 0.0058 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0276 | 0.0913 | 0.1925 |
Loa Loa (eye worm) | fibroinase | 0.0017 | 0.0032 | 0.0056 |
Loa Loa (eye worm) | runx1 | 0.0055 | 0.0163 | 0.0332 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0032 | 0.0034 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0072 | 0.0143 |
Leishmania major | cathepsin L-like protease | 0.0063 | 0.019 | 0.955 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0072 | 0.0141 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0017 | 0.0032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1268 | 0.4283 | 0.9063 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.1398 | 0.4725 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.013 | 0.0418 | 0.0874 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.013 | 0.0418 | 0.044 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0078 | 0.0078 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0032 | 0.0058 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0146 | 0.0471 | 0.0986 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.0032 | 0.0058 |
Onchocerca volvulus | Cathepsin F homolog | 0.0017 | 0.0032 | 0.0036 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0032 | 0.1415 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.0913 | 0.1923 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0009 | 0.0005 | 0.0005 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0276 | 0.0913 | 0.0961 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.019 | 0.9614 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0065 | 0.0198 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0471 | 0.0986 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.0138 | 0.0282 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.013 | 0.0418 | 0.0418 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0418 | 0.0874 |
Schistosoma mansoni | nuclear hormone receptor | 0.013 | 0.0418 | 0.0418 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0276 | 0.0913 | 0.1728 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0276 | 0.0913 | 0.1925 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0138 | 0.0138 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0011 | 0.0014 | 0.0018 |
Onchocerca volvulus | 0.0017 | 0.0032 | 0.0036 | |
Echinococcus granulosus | cathepsin l1 | 0.0017 | 0.0032 | 0.0032 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0146 | 0.0471 | 0.0988 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0276 | 0.0913 | 0.1925 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0078 | 0.0078 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0276 | 0.0913 | 0.0961 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0276 | 0.0913 | 0.1923 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.013 | 0.0418 | 0.0875 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0276 | 0.0913 | 0.1923 |
Onchocerca volvulus | 0.0017 | 0.0032 | 0.0036 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0032 | 0.0056 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.013 | 0.0418 | 0.0875 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0276 | 0.0913 | 0.0913 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.019 | 0.9614 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0276 | 0.0913 | 0.0913 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0146 | 0.0471 | 0.0988 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.013 | 0.0418 | 0.0418 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0276 | 0.0913 | 0.0961 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.019 | 0.9614 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0032 | 0.0034 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0032 | 0.0036 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0011 | 0.0014 | 0.045 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.018 | 0.018 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0009 | 0.0005 | 0.0005 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0276 | 0.0913 | 0.0913 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0146 | 0.0471 | 0.0471 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0017 | 0.0032 | 0.0056 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0009 | 0.0005 | 0.0005 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.013 | 0.0418 | 0.0875 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.0913 | 0.1923 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0032 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.0913 | 0.1923 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0418 | 0.0874 |
Brugia malayi | nuclear receptor NHR-67 | 0.013 | 0.0418 | 0.0875 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0276 | 0.0913 | 0.0913 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.013 | 0.0418 | 0.0418 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0276 | 0.0913 | 0.0961 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.0159 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.2951 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.0913 | 0.1923 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.019 | 0.9614 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.0913 | 0.1923 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0032 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.013 | 0.0418 | 0.0418 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0032 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0471 | 0.0986 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0063 | 0.019 | 0.9614 |
Schistosoma mansoni | nuclear receptor | 0.013 | 0.0418 | 0.0418 |
Onchocerca volvulus | 0.0017 | 0.0032 | 0.0036 | |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0418 | 0.0874 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0198 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0418 | 0.0874 |
Onchocerca volvulus | 0.0017 | 0.0032 | 0.0036 | |
Onchocerca volvulus | 0.0017 | 0.0032 | 0.0036 | |
Schistosoma mansoni | lozenge | 0.0055 | 0.0163 | 0.0163 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0063 | 0.019 | 0.9614 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0006 | 0.0006 |
Echinococcus multilocularis | Protein lozenge | 0.0055 | 0.0163 | 0.0171 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0276 | 0.0913 | 0.0913 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0017 | 0.0032 | 0.0032 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0078 | 0.0082 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0146 | 0.0471 | 0.0988 |
Onchocerca volvulus | 0.0017 | 0.0032 | 0.0036 | |
Onchocerca volvulus | 0.013 | 0.0418 | 0.0777 | |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0146 | 0.0471 | 0.0471 |
Schistosoma mansoni | nuclear hormone receptor | 0.0276 | 0.0913 | 0.0913 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC95 (functional) | = 40 ug ml-1 | Antimycobacterial activity against Mycobacterium smegmatis mc2155 after 48 hrs by microdilution resazurin assay | ChEMBL. | 17208445 |
MIC95 (functional) | > 500 ug ml-1 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 6 days by microdilution resazurin assay | ChEMBL. | 17208445 |
MIC95 (functional) | > 500 ug ml-1 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 6 days by microdilution resazurin assay | ChEMBL. | 17208445 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.