Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | nuclear receptor NHR-67 | 0.0056 | 0.1339 | 0.1339 |
Brugia malayi | hypothetical protein | 0.0056 | 0.1339 | 0.1339 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0056 | 0.1339 | 0.1339 |
Giardia lamblia | Aurora kinase | 0.0293 | 1 | 0.5 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0119 | 0.3639 | 0.3639 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0119 | 0.3639 | 0.3122 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0119 | 0.3639 | 0.3639 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0063 | 0.1585 | 0.1129 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0063 | 0.1585 | 0.1585 |
Brugia malayi | nuclear hormone receptor | 0.0119 | 0.3639 | 0.3639 |
Brugia malayi | nuclear receptor RXR | 0.0056 | 0.1339 | 0.1339 |
Brugia malayi | nuclear receptor NHR-88 | 0.0056 | 0.1339 | 0.1339 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0119 | 0.3639 | 0.3294 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.3639 | 0.3122 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0063 | 0.1585 | 0.1585 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0119 | 0.3639 | 0.3122 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0119 | 0.3639 | 0.3639 |
Schistosoma mansoni | thyroid hormone receptor | 0.0119 | 0.3639 | 0.3639 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0293 | 1 | 0.5 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0119 | 0.3639 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0293 | 1 | 0.5 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0049 | 0.1091 | 0.0609 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1585 | 0.09 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0293 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1339 | 0.0634 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0119 | 0.3639 | 0.3294 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1339 | 0.0634 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0119 | 0.3639 | 0.3294 |
Brugia malayi | steroid hormone receptor | 0.0119 | 0.3639 | 0.3639 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0293 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0056 | 0.1339 | 0.0634 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0119 | 0.3639 | 0.3639 |
Brugia malayi | tailless protein | 0.0056 | 0.1339 | 0.1339 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.3639 | 0.3122 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0119 | 0.3639 | 0.3639 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1339 | 0.0634 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0119 | 0.3639 | 0.3294 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0119 | 0.3639 | 0.3639 |
Brugia malayi | conserved hypotetical protein | 0.0056 | 0.1339 | 0.1339 |
Entamoeba histolytica | protein kinase, putative | 0.0293 | 1 | 0.5 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0036 | 0.0614 | 0.0614 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0119 | 0.3639 | 0.3639 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0056 | 0.1339 | 0.0869 |
Onchocerca volvulus | 0.0119 | 0.3639 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1339 | 0.0634 |
Loa Loa (eye worm) | AUR protein kinase | 0.0293 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0119 | 0.3639 | 0.3639 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0056 | 0.1339 | 0.0869 |
Brugia malayi | hypothetical protein | 0.0056 | 0.1339 | 0.1339 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0056 | 0.1339 | 0.0869 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0119 | 0.3639 | 0.3639 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.3639 | 0.3122 |
Brugia malayi | nuclear hormone receptor | 0.0056 | 0.1339 | 0.1339 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0119 | 0.3639 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0119 | 0.3639 | 0.3294 |
Toxoplasma gondii | aurora kinase | 0.0293 | 1 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0293 | 1 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0063 | 0.1585 | 0.1585 |
Trypanosoma brucei | aurora B kinase | 0.0293 | 1 | 0.5 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0056 | 0.1339 | 0.1339 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0056 | 0.1339 | 0.0869 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.3639 | 0.3122 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0056 | 0.1339 | 0.1339 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0119 | 0.3639 | 1 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0049 | 0.1091 | 0.0609 |
Leishmania major | protein kinase, putative | 0.0293 | 1 | 0.5 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0293 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0119 | 0.3639 | 0.3122 |
Schistosoma mansoni | zinc finger protein | 0.0056 | 0.1339 | 0.1339 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1585 | 0.09 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0293 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0056 | 0.1339 | 0.0869 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0119 | 0.3639 | 0.3639 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0034 | 0.0514 | 0.0514 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0293 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1585 | 0.09 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0119 | 0.3639 | 0.3639 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.3639 | 0.3122 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0293 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0119 | 0.3639 | 0.3639 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1339 | 0.0634 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1339 | 0.0634 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0293 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0063 | 0.1585 | 0.1585 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0056 | 0.1339 | 0.1339 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0056 | 0.1339 | 0.0634 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0056 | 0.1339 | 0.0869 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0293 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1339 | 0.0634 |
Schistosoma mansoni | nuclear hormone receptor | 0.0119 | 0.3639 | 0.3639 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0119 | 0.3639 | 0.3639 |
Entamoeba histolytica | protein kinase , putative | 0.0293 | 1 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0056 | 0.1339 | 0.0869 |
Echinococcus granulosus | aurora kinase A | 0.0293 | 1 | 1 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.004 | 0.0752 | 0.0752 |
Schistosoma mansoni | coup transcription factor | 0.0119 | 0.3639 | 0.3639 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0119 | 0.3639 | 0.3639 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0119 | 0.3639 | 0.3639 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0119 | 0.3639 | 0.3294 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0119 | 0.3639 | 0.3122 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.3639 | 0.3122 |
Schistosoma mansoni | nuclear receptor | 0.0056 | 0.1339 | 0.1339 |
Brugia malayi | serine/threonine kinase 12 | 0.0293 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0056 | 0.1339 | 0.1339 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0119 | 0.3639 | 0.3294 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1339 | 0.0634 |
Schistosoma mansoni | thyroid hormone receptor | 0.0119 | 0.3639 | 0.3639 |
Loa Loa (eye worm) | DR-78 | 0.0056 | 0.1339 | 0.0634 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.3639 | 0.3122 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1339 | 0.0634 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.3639 | 0.3122 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0119 | 0.3639 | 0.3294 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0119 | 0.3639 | 0.3639 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0119 | 0.3639 | 0.3122 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0056 | 0.1339 | 0.1339 |
Loa Loa (eye worm) | AUR protein kinase | 0.0293 | 1 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0056 | 0.1339 | 0.1339 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1585 | 0.09 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0119 | 0.3639 | 0.3639 |
Brugia malayi | ecdysone receptor | 0.0056 | 0.1339 | 0.1339 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0119 | 0.3639 | 0.3639 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0119 | 0.3639 | 0.3294 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0119 | 0.3639 | 0.3294 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0056 | 0.1339 | 0.0869 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0119 | 0.3639 | 0.3122 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0119 | 0.3639 | 0.3639 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0119 | 0.3639 | 0.3294 |
Echinococcus multilocularis | aurora kinase A | 0.0293 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1585 | 0.09 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0056 | 0.1339 | 0.0869 |
Schistosoma mansoni | nuclear receptor | 0.0056 | 0.1339 | 0.1339 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0119 | 0.3639 | 0.3294 |
Brugia malayi | nuclear receptor RXR | 0.0063 | 0.1585 | 0.1585 |
Trichomonas vaginalis | AGC family protein kinase | 0.0293 | 1 | 0.5 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0056 | 0.1339 | 0.0869 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0293 | 1 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0119 | 0.3639 | 0.3639 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1339 | 0.0634 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0063 | 0.1585 | 0.1585 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1339 | 0.0634 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0119 | 0.3639 | 0.3294 |
Brugia malayi | hypothetical protein | 0.0063 | 0.1585 | 0.1585 |
Brugia malayi | ecdysteroid receptor | 0.0119 | 0.3639 | 0.3639 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0056 | 0.1339 | 0.0869 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0119 | 0.3639 | 0.3639 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0119 | 0.3639 | 0.3122 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1339 | 0.0634 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0119 | 0.3639 | 0.3294 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0056 | 0.1339 | 0.1339 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0119 | 0.3639 | 0.3639 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0119 | 0.3639 | 0.3294 |
Schistosoma mansoni | nuclear hormone receptor | 0.0056 | 0.1339 | 0.1339 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0046 | 0.0953 | 0.0953 |
Brugia malayi | nuclear receptor NHR-88 | 0.0119 | 0.3639 | 0.3639 |
Trichomonas vaginalis | AGC family protein kinase | 0.0293 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0063 | 0.1585 | 0.09 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0056 | 0.1339 | 0.1339 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0119 | 0.3639 | 0.3294 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0056 | 0.1339 | 0.1339 |
Trichomonas vaginalis | AGC family protein kinase | 0.0293 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1339 | 0.0634 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0119 | 0.3639 | 0.3639 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0293 | 1 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0056 | 0.1339 | 0.0869 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0119 | 0.3639 | 0.3294 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0119 | 0.3639 | 0.3294 |
Loa Loa (eye worm) | AUR protein kinase | 0.0293 | 1 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0056 | 0.1339 | 0.0634 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0119 | 0.3639 | 0.3639 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1091 | 0.0367 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0119 | 0.3639 | 0.3639 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0063 | 0.1585 | 0.1129 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0119 | 0.3639 | 0.3122 |
Schistosoma mansoni | protein kinase | 0.0293 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.