Detailed information for compound 452413

Basic information

Technical information
  • TDR Targets ID: 452413
  • Name: 6-benzyl-5-methyl-N-morpholin-4-yl-1,1-dioxo- 1,2,6-thiadiazine-3-carboxamide
  • MW: 364.419 | Formula: C16H20N4O4S
  • H donors: 1 H acceptors: 3 LogP: 0.58 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1=CC(=NS(=O)(=O)N1Cc1ccccc1)C(=O)NN1CCOCC1
  • InChi: 1S/C16H20N4O4S/c1-13-11-15(16(21)17-19-7-9-24-10-8-19)18-25(22,23)20(13)12-14-5-3-2-4-6-14/h2-6,11H,7-10,12H2,1H3,(H,17,21)
  • InChiKey: MOMSLSHRCUXFIG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 6-benzyl-5-methyl-N-morpholino-1,1-dioxo-1,2,6-thiadiazine-3-carboxamide
  • 5-methyl-N-morpholin-4-yl-1,1-dioxo-6-(phenylmethyl)-1,2,6-thiadiazine-3-carboxamide
  • 6-benzyl-1,1-diketo-5-methyl-N-morpholino-1,2,6-thiadiazine-3-carboxamide
  • 5-methyl-N-morpholino-1,1-dioxo-6-(phenylmethyl)-1,2,6-thiadiazine-3-carboxamide
  • 6-(benzyl)-1,1-diketo-5-methyl-N-morpholino-1,2,6-thiadiazine-3-carboxamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0076 0.008 0.0099
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0535 0.463 1
Brugia malayi G protein-coupled receptor 0.0076 0.008 0.0029
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0076 0.008 0.008
Loa Loa (eye worm) proprotein convertase 2 0.0208 0.1388 0.1724
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0076 0.008 0.0099
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0208 0.1388 0.1724
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.008 0.0099
Echinococcus granulosus neuropeptide Y receptor 0.0076 0.008 0.008
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0076 0.008 0.008
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.008 0.0099
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Schistosoma mansoni adenoreceptor 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0208 0.1388 0.1032
Echinococcus multilocularis G-protein coupled receptor, putative 0.0076 0.008 0.008
Echinococcus multilocularis neuropeptide s receptor 0.0076 0.008 0.008
Echinococcus granulosus biogenic amine 5HT receptor 0.0076 0.008 0.008
Schistosoma mansoni amine GPCR 0.0076 0.008 0.0099
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0076 0.008 0.0099
Brugia malayi hypothetical protein 0.0076 0.008 0.0029
Brugia malayi Dopamine receptor protein 2 0.0076 0.008 0.0029
Schistosoma mansoni amine GPCR 0.0076 0.008 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.008 0.0099
Brugia malayi Dopamine receptor protein 1 0.0076 0.008 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.008 0.008
Onchocerca volvulus Neuropeptide F receptor homolog 0.0076 0.008 1
Echinococcus multilocularis allatostatin A receptor 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Brugia malayi proprotein convertase 2 0.0553 0.481 0.5945
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0076 0.008 0.0099
Echinococcus granulosus furin 0.088 0.8052 0.8052
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.008 0.008
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.088 0.8052 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0208 0.1388 0.1032
Echinococcus multilocularis neuropeptides capa receptor 0.0076 0.008 0.008
Echinococcus granulosus neuropeptide s receptor 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Onchocerca volvulus 0.0076 0.008 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.008 0.008
Echinococcus multilocularis neuropeptide receptor 0.0386 0.3155 0.3155
Echinococcus granulosus g protein coupled receptor 0.0076 0.008 0.008
Loa Loa (eye worm) melatonin receptor type 1A 0.0076 0.008 0.0099
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0076 0.008 0.0029
Giardia lamblia High cysteine membrane protein Group 2 0.0327 0.257 1
Schistosoma mansoni amine GPCR 0.0076 0.008 0.0099
Echinococcus multilocularis somatostatin receptor 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Brugia malayi G protein-coupled receptor F59B2.13 0.0076 0.008 0.0029
Schistosoma mansoni neuropeptide receptor 0.0386 0.3155 0.3918
Onchocerca volvulus 0.0076 0.008 1
Echinococcus granulosus g-protein coupled receptor 0.0076 0.008 0.008
Onchocerca volvulus 0.0076 0.008 1
Schistosoma mansoni neuropeptide F-like receptor 0.0076 0.008 0.0099
Echinococcus multilocularis neuropeptide Y receptor 0.0076 0.008 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Echinococcus granulosus peptide allatostatin:somatostatin 0.0076 0.008 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.008 0.0099
Schistosoma mansoni growth hormone secretagogue receptor 0.0076 0.008 0.0099
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0208 0.1388 0.1032
Brugia malayi endoprotease bli-4 precursor 0.088 0.8052 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0076 0.008 0.0099
Schistosoma mansoni neuropeptide receptor 0.0076 0.008 0.0099
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0076 0.008 0.0099
Onchocerca volvulus 0.0076 0.008 1
Brugia malayi hypothetical protein 0.0076 0.008 0.0029
Echinococcus granulosus G protein coupled receptor 139 0.0076 0.008 0.008
Brugia malayi hypothetical protein 0.0076 0.008 0.0029
Echinococcus multilocularis g protein coupled receptor 0.0076 0.008 0.008
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0535 0.463 0.463
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0076 0.008 0.008
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0076 0.008 0.008
Schistosoma mansoni biogenic amine receptor 0.0076 0.008 0.0099
Brugia malayi hypothetical protein 0.0076 0.008 0.0029
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0076 0.008 0.008
Echinococcus granulosus Furin 1 0.0208 0.1388 0.1388
Schistosoma mansoni amine GPCR 0.0076 0.008 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.008 0.0099
Echinococcus multilocularis dro:myosuppressin receptor 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0074 0.0057 0.0071
Schistosoma mansoni opsin-like receptor 0.0076 0.008 0.0099
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0076 0.008 0.0099
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0208 0.1388 0.1032
Echinococcus multilocularis neuroendocrine convertase 2 0.0553 0.481 0.481
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Echinococcus multilocularis g-protein coupled receptor 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Trypanosoma brucei RNA helicase, putative 0.0101 0.0326 0.5
Onchocerca volvulus 0.0076 0.008 1
Echinococcus granulosus neuropeptide Y receptor 0.0076 0.008 0.008
Echinococcus multilocularis serotonin receptor 0.0076 0.008 0.008
Schistosoma mansoni furin-1 (S08 family) 0.0383 0.3123 0.3878
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Echinococcus granulosus tm gpcr rhodopsin 0.0076 0.008 0.008
Onchocerca volvulus 0.0076 0.008 1
Brugia malayi neuropeptide F receptor 0.0076 0.008 0.0029
Echinococcus granulosus neuropeptide receptor 0.0076 0.008 0.008
Onchocerca volvulus 0.0076 0.008 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Echinococcus multilocularis g protein coupled receptor 0.0076 0.008 0.008
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0076 0.008 0.008
Schistosoma mansoni neuropeptide receptor 0.0076 0.008 0.0099
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0076 0.008 0.0099
Schistosoma mansoni myosin xvIII 0.0076 0.008 0.0099
Schistosoma mansoni biogenic amine receptor 0.0076 0.008 0.0099
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0076 0.008 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.008 0.008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0076 0.008 0.0099
Onchocerca volvulus 0.0076 0.008 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0076 0.008 0.008
Brugia malayi Serotonin receptor 0.0076 0.008 0.0029
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Echinococcus granulosus hypothetical protein 0.0076 0.008 0.008
Echinococcus granulosus alpha 1A adrenergic receptor 0.0076 0.008 0.008
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0076 0.008 0.0029
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0076 0.008 0.0099
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0076 0.008 0.0099
Onchocerca volvulus 0.0076 0.008 1
Brugia malayi hypothetical protein 0.0076 0.008 0.0029
Schistosoma mansoni neuropeptide receptor 0.0076 0.008 0.0099
Schistosoma mansoni opsin-like receptor 0.0076 0.008 0.0099
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.008 0.008
Echinococcus granulosus serotonin receptor 0.0076 0.008 0.008
Onchocerca volvulus 0.0076 0.008 1
Schistosoma mansoni hypothetical protein 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0076 0.008 0.008
Echinococcus multilocularis G protein coupled receptor 139 0.0386 0.3155 0.3155
Brugia malayi putative neuropeptide receptor NPR1 0.0076 0.008 0.0029
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Brugia malayi GnHR receptor homolog 0.0076 0.008 0.0029
Schistosoma mansoni hypothetical protein 0.0076 0.008 0.0099
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.008 0.008
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0076 0.008 0.008
Echinococcus granulosus neuropeptide receptor A26 0.0076 0.008 0.008
Brugia malayi Dopamine receptor 0.0076 0.008 0.0029
Echinococcus multilocularis g protein coupled receptor 0.0076 0.008 0.008
Echinococcus multilocularis neuropeptide Y receptor 0.0076 0.008 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Schistosoma mansoni serine-type protease inhibitor 0.0431 0.36 0.4471
Echinococcus granulosus neuroendocrine convertase 2 0.0553 0.481 0.481
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0076 0.008 0.0099
Echinococcus multilocularis sex peptide receptor 0.0076 0.008 0.008
Brugia malayi hypothetical protein 0.0076 0.008 0.0029
Brugia malayi Serotonin receptor 0.0076 0.008 0.0029
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Brugia malayi Tachykinin-like peptides receptor 99D 0.0076 0.008 0.0029
Echinococcus granulosus tachykinin peptides receptor 99D 0.0076 0.008 0.008
Schistosoma mansoni biogenic amine (5HT) receptor 0.0076 0.008 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.008 0.0099
Echinococcus multilocularis serotonin receptor 0.0076 0.008 0.008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0076 0.008 0.0099
Schistosoma mansoni alpha-1 adrenergic receptor 0.0076 0.008 0.0099
Schistosoma mansoni hypothetical protein 0.0101 0.0326 0.0404
Onchocerca volvulus 0.0076 0.008 1
Echinococcus granulosus neuropeptide receptor 0.0386 0.3155 0.3155
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0076 0.008 0.0099
Loa Loa (eye worm) G-protein coupled receptor 0.0076 0.008 0.0099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.008 0.008
Schistosoma mansoni neuropeptide f receptor 76f 0.0076 0.008 0.0099
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0076 0.008 0.008
Brugia malayi follicle stimulating hormone receptor 0.0076 0.008 0.0029
Loa Loa (eye worm) G-protein coupled receptor 0.0076 0.008 0.0099
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1076 1 1
Brugia malayi hypothetical protein 0.0076 0.008 0.0029
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0076 0.008 0.0099
Brugia malayi hypothetical protein 0.0076 0.008 0.0029
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Onchocerca volvulus 0.0076 0.008 1
Echinococcus multilocularis fmrfamide receptor 0.0076 0.008 0.008
Schistosoma mansoni biogenic amine (5HT) receptor 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0345 0.275 0.3415
Echinococcus granulosus neuropeptides capa receptor 0.0076 0.008 0.008
Onchocerca volvulus 0.0076 0.008 1
Echinococcus granulosus g protein coupled receptor 0.0076 0.008 0.008
Brugia malayi G-protein coupled receptor 0.0076 0.008 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.008 0.008
Echinococcus granulosus fmrfamide receptor 0.0076 0.008 0.008
Echinococcus granulosus biogenic amine 5HT receptor 0.0076 0.008 0.008
Echinococcus granulosus neuropeptide FF receptor 2 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Brugia malayi neuropeptide F receptor 0.0076 0.008 0.0029
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0076 0.008 0.008
Onchocerca volvulus 0.0076 0.008 1
Echinococcus granulosus neuropeptides capa receptor 0.0076 0.008 0.008
Brugia malayi RE15519p 0.0076 0.008 0.0029
Schistosoma mansoni amine GPCR 0.0076 0.008 0.0099
Brugia malayi putative neuropeptide receptor 0.0076 0.008 0.0029
Echinococcus granulosus allatostatin A receptor 0.0076 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0076 0.008 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.008 0.0099
Brugia malayi celfurPC protein 0.0709 0.6365 0.7889
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Brugia malayi hypothetical protein 0.0076 0.008 0.0029
Echinococcus multilocularis Furin 1 0.0208 0.1388 0.1388
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Echinococcus multilocularis orexin receptor type 2 0.0076 0.008 0.008
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0076 0.008 0.0029
Brugia malayi ORL1-like opioid receptor 0.0076 0.008 0.0029
Brugia malayi hypothetical protein 0.0076 0.008 0.0029
Schistosoma mansoni hypothetical protein 0.0076 0.008 0.0099
Echinococcus multilocularis neuropeptide receptor 0.0076 0.008 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0076 0.008 0.0099
Echinococcus granulosus 7tm_1 domain containing protein 0.0076 0.008 0.008
Schistosoma mansoni hypothetical protein 0.017 0.1015 0.1261
Loa Loa (eye worm) neuropeptide F receptor 0.0076 0.008 0.0099
Echinococcus granulosus dro:myosuppressin receptor 0.0076 0.008 0.008
Echinococcus granulosus 7TM GPCR rhodopsin 0.0076 0.008 0.008
Brugia malayi G-protein coupled receptor 0.0076 0.008 0.0029
Loa Loa (eye worm) hypothetical protein 0.088 0.8052 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0208 0.1388 0.1032
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Echinococcus granulosus sex peptide receptor 0.0076 0.008 0.008
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0076 0.008 0.008
Onchocerca volvulus 0.0076 0.008 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.008 0.008
Onchocerca volvulus 0.0076 0.008 1
Echinococcus multilocularis neuropeptide receptor A26 0.0076 0.008 0.008
Echinococcus multilocularis fmrfamide receptor 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Brugia malayi larval opioid receptor 0.0076 0.008 0.0029
Brugia malayi neuroendocrine convertase 1 precursor 0.0553 0.481 0.5945
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0208 0.1388 0.1032
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0076 0.008 0.008
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0076 0.008 0.0029
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0076 0.008 0.0099
Echinococcus granulosus somatostatin receptor 0.0076 0.008 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0076 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Brugia malayi Melatonin receptor type 1A 0.0076 0.008 0.0029
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0076 0.008 0.0029
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Loa Loa (eye worm) endoprotease bli-4 0.088 0.8052 1
Echinococcus multilocularis 0.0709 0.6365 0.6365
Echinococcus granulosus orexin receptor type 2 0.0076 0.008 0.008
Echinococcus multilocularis neuropeptide FF receptor 2 0.0076 0.008 0.008
Schistosoma mansoni biogenic amine receptor 0.0076 0.008 0.0099
Brugia malayi sulfakinin receptor protein 0.0076 0.008 0.0029
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0076 0.008 0.0099
Schistosoma mansoni histamine h1 receptor 0.0076 0.008 0.0099
Echinococcus granulosus tm gpcr rhodopsin 0.0076 0.008 0.008
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0535 0.463 0.463
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0076 0.008 1
Schistosoma mansoni serine-type protease inhibitor 0.0431 0.36 0.4471
Onchocerca volvulus 0.0076 0.008 1
Schistosoma mansoni opsin-like receptor 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Brugia malayi AKH receptor 0.0076 0.008 0.0029
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0535 0.463 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099
Echinococcus granulosus g protein coupled receptor 0.0076 0.008 0.008
Loa Loa (eye worm) TYRA-2 protein 0.0076 0.008 0.0099
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0076 0.008 0.008
Loa Loa (eye worm) neuropeptide F receptor 0.0076 0.008 0.0099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0076 0.008 0.008
Echinococcus multilocularis neuropeptides capa receptor 0.0076 0.008 0.008
Schistosoma mansoni neuropeptide F-like receptor 0.0076 0.008 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.008 0.0099

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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