Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0071 | 0.0831 | 0.2828 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0025 | 0.0101 | 0.0113 |
Brugia malayi | MH1 domain containing protein | 0.0035 | 0.0257 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0388 | 0.5765 | 0.673 |
Brugia malayi | MH2 domain containing protein | 0.0035 | 0.0257 | 0.03 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0025 | 0.0101 | 0.0117 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0055 | 0.0583 | 0.0726 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0175 | 0.0205 |
Echinococcus granulosus | zinc finger protein | 0.0054 | 0.0554 | 0.0801 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0206 | 0.2929 | 0.5127 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.005 | 0.0494 | 0.204 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0071 | 0.0831 | 0.145 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0059 | 0.0641 | 0.0928 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0383 | 0.0443 |
Schistosoma mansoni | ferritin | 0.0025 | 0.0106 | 0.0106 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.019 | 0.2683 | 0.3133 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0071 | 0.0831 | 0.145 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0071 | 0.0831 | 0.2857 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0071 | 0.0831 | 0.145 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0055 | 0.0583 | 0.0726 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0126 | 0.1675 | 0.2434 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.0019 | 0.0014 | 0.0048 |
Echinococcus multilocularis | GPCR, family 2 | 0.018 | 0.2517 | 0.3665 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0055 | 0.0583 | 0.0849 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.047 | 0.7042 | 0.8958 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0019 | 0.0014 | 0.0015 |
Leishmania major | 2,4-dienoyl-coa reductase fadh1, putative | 0.0019 | 0.0014 | 0.0018 |
Brugia malayi | RNA binding protein | 0.0047 | 0.0454 | 0.053 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0055 | 0.0583 | 0.1015 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0041 | 0.036 | 0.036 |
Schistosoma mansoni | ferritin | 0.0025 | 0.0106 | 0.0106 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0052 | 0.0536 | 0.0626 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0384 | 0.5709 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0087 | 0.1069 | 0.1557 |
Mycobacterium ulcerans | hypothetical protein | 0.0055 | 0.0583 | 0.199 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0019 | 0.0014 | 0.0042 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.2517 | 0.2517 |
Echinococcus granulosus | death domain containing protein | 0.0025 | 0.0101 | 0.0141 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0031 | 0.0201 | 0.0688 |
Brugia malayi | Bromodomain containing protein | 0.0187 | 0.2637 | 0.3079 |
Trypanosoma brucei | ISWI complex protein | 0.0037 | 0.0294 | 0.0508 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0072 | 0.0841 | 0.1467 |
Plasmodium falciparum | thioredoxin reductase | 0.0206 | 0.2929 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0019 | 0.0016 | 0.0019 |
Plasmodium vivax | NAD(P)H-dependent glutamate synthase, putative | 0.0019 | 0.0014 | 0.0048 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0041 | 0.0365 | 0.1227 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0041 | 0.036 | 0.036 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0384 | 0.5709 | 1 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0035 | 0.0257 | 0.0374 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0071 | 0.0831 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0055 | 0.0583 | 0.0681 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0201 | 0.0231 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0087 | 0.1069 | 0.1552 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0019 | 0.0014 | 0.002 |
Echinococcus granulosus | GPCR family 2 | 0.018 | 0.2517 | 0.3661 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0072 | 0.0841 | 0.1467 |
Schistosoma mansoni | glutamate synthase | 0.0019 | 0.0014 | 0.0014 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0054 | 0.0561 | 0.0976 |
Onchocerca volvulus | 0.0055 | 0.0583 | 0.3106 | |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0041 | 0.0365 | 0.0447 |
Brugia malayi | beta-lactamase family protein | 0.0055 | 0.0583 | 0.0681 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0031 | 0.0201 | 0.2294 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0035 | 0.0257 | 0.0374 |
Echinococcus multilocularis | Ankyrin | 0.0025 | 0.0104 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0583 | 0.0677 |
Onchocerca volvulus | 0.0032 | 0.0221 | 0.1175 | |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0071 | 0.0831 | 0.1205 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0047 | 0.0454 | 0.053 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1161 | 0.1352 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0019 | 0.0014 | 0.002 |
Mycobacterium tuberculosis | Conserved protein | 0.0055 | 0.0583 | 0.0726 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0583 | 0.0677 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0018 | 0.0004 | 0.0014 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0014 | 0.0014 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0072 | 0.0841 | 0.1467 |
Echinococcus multilocularis | caspase | 0.0018 | 0.0004 | 0.0006 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0071 | 0.0831 | 0.145 |
Mycobacterium tuberculosis | Conserved protein | 0.0055 | 0.0583 | 0.0726 |
Trypanosoma brucei | 2,4-dienoyl-coa reductase-like protein | 0.0019 | 0.0014 | 0.0018 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0071 | 0.0831 | 1 |
Plasmodium vivax | metacaspase 1, putative | 0.0018 | 0.0004 | 0.0014 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0203 | 0.2874 | 0.3646 |
Echinococcus granulosus | tar DNA binding protein | 0.0047 | 0.0454 | 0.0655 |
Brugia malayi | Thioredoxin reductase | 0.0206 | 0.2929 | 0.3421 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0071 | 0.0831 | 0.2857 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.017 | 0.2365 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0583 | 0.0677 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0071 | 0.0831 | 0.145 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0019 | 0.0014 | 0.0018 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0019 | 0.0014 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0568 | 0.8563 | 1 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0179 | 0.2513 | 0.3655 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0019 | 0.0014 | 0.0012 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0055 | 0.0583 | 0.2453 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.2517 | 0.2517 |
Trypanosoma brucei | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0019 | 0.0014 | 0.0018 |
Trypanosoma cruzi | ISWI complex protein | 0.0037 | 0.0294 | 0.0508 |
Schistosoma mansoni | apoferritin-2 | 0.0025 | 0.0106 | 0.0106 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0182 | 0.2554 | 0.4469 |
Mycobacterium ulcerans | beta-lactamase | 0.0055 | 0.0583 | 0.199 |
Schistosoma mansoni | tar DNA-binding protein | 0.0047 | 0.0454 | 0.0454 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0083 | 0.1012 | 0.3488 |
Brugia malayi | MH2 domain containing protein | 0.0035 | 0.0257 | 0.03 |
Trypanosoma cruzi | ISWI complex protein | 0.0037 | 0.0294 | 0.0508 |
Loa Loa (eye worm) | Smad1 | 0.0035 | 0.0257 | 0.0295 |
Mycobacterium leprae | Probable lipase LipE | 0.0055 | 0.0583 | 0.0726 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0019 | 0.0014 | 0.0018 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0035 | 0.0257 | 0.0295 |
Toxoplasma gondii | thioredoxin reductase | 0.0206 | 0.2929 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0071 | 0.0831 | 0.2838 |
Brugia malayi | Pre-SET motif family protein | 0.0122 | 0.1614 | 0.1885 |
Onchocerca volvulus | Netrin receptor homolog | 0.0025 | 0.0101 | 0.0536 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0019 | 0.0014 | 0.0042 |
Schistosoma mansoni | glutamate synthase | 0.0019 | 0.0014 | 0.0014 |
Brugia malayi | beta-lactamase | 0.0055 | 0.0583 | 0.0681 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.006 | 0.0653 | 0.2749 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0071 | 0.0831 | 0.3503 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0055 | 0.0583 | 0.0583 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0641 | 0.0744 |
Onchocerca volvulus | 0.0055 | 0.0583 | 0.3106 | |
Echinococcus multilocularis | cpg binding protein | 0.0039 | 0.0321 | 0.0468 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0055 | 0.0583 | 0.0677 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0055 | 0.0583 | 0.0844 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.006 | 0.0653 | 0.223 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0101 | 0.0101 |
Loa Loa (eye worm) | acetyltransferase | 0.019 | 0.2683 | 0.313 |
Onchocerca volvulus | 0.0043 | 0.0383 | 0.2039 | |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0018 | 0.0004 | 0.0005 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0054 | 0.0561 | 0.0976 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0061 | 0.0668 | 0.0668 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0054 | 0.0561 | 0.0976 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0071 | 0.0831 | 0.0971 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0071 | 0.0831 | 1 |
Echinococcus granulosus | caspase 8 | 0.0018 | 0.0004 | 0.000000048754 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.1421 | 0.1655 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0384 | 0.5709 | 1 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0019 | 0.0014 | 0.0018 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0019 | 0.0014 | 0.0018 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0052 | 0.0536 | 0.0626 |
Toxoplasma gondii | hypothetical protein | 0.0062 | 0.0685 | 0.2338 |
Brugia malayi | glutamate synthase | 0.0019 | 0.0014 | 0.0016 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0059 | 0.0641 | 0.0933 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0025 | 0.0101 | 0.0146 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.017 | 0.2365 | 1 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0019 | 0.0014 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0583 | 0.0677 |
Loa Loa (eye worm) | hypothetical protein | 0.018 | 0.2517 | 0.2936 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.017 | 0.2365 | 1 |
Echinococcus granulosus | dnaJ subfamily B | 0.0459 | 0.6868 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0583 | 0.0677 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0206 | 0.2929 | 0.3417 |
Brugia malayi | Latrophilin receptor protein 2 | 0.018 | 0.2517 | 0.294 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0019 | 0.0014 | 0.0015 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0071 | 0.0831 | 0.145 |
Plasmodium vivax | type II NADH:ubiquinone oxidoreductase, putative | 0.0019 | 0.0014 | 0.0048 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0071 | 0.0831 | 0.3503 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0071 | 0.0831 | 0.1042 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0054 | 0.0561 | 0.0976 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0071 | 0.0831 | 0.145 |
Echinococcus multilocularis | tar DNA binding protein | 0.0047 | 0.0454 | 0.0661 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0019 | 0.0014 | 0.0042 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0035 | 0.0257 | 0.0368 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase fadh1, putative | 0.0019 | 0.0014 | 0.0018 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0182 | 0.2554 | 0.4469 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0668 | 0.0776 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0041 | 0.0365 | 0.1492 |
Brugia malayi | glutathione reductase | 0.0206 | 0.2929 | 0.3421 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0041 | 0.0365 | 0.0632 |
Brugia malayi | Uncoordinated protein 44 | 0.0025 | 0.0101 | 0.0117 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.018 | 0.2517 | 0.3665 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0041 | 0.0365 | 0.0632 |
Leishmania major | hypothetical protein, conserved | 0.0019 | 0.0014 | 0.0018 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0041 | 0.0365 | 0.0447 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0019 | 0.0014 | 0.0018 |
Leishmania major | 2,4-dienoyl-coa reductase-like protein | 0.0019 | 0.0014 | 0.0018 |
Echinococcus granulosus | ferritin | 0.0025 | 0.0106 | 0.0149 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0019 | 0.0014 | 0.0042 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0025 | 0.0106 | 0.0393 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0019 | 0.0014 | 0.0018 |
Echinococcus multilocularis | glutamate synthase | 0.0019 | 0.0014 | 0.002 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0055 | 0.0583 | 0.1015 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0583 | 0.0677 |
Plasmodium vivax | hypothetical protein, conserved | 0.0055 | 0.0583 | 0.1991 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0035 | 0.0257 | 0.0295 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0055 | 0.0583 | 0.0726 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.006 | 0.0653 | 0.0946 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0221 | 0.0221 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.0221 | 0.0253 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0055 | 0.0583 | 0.199 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0071 | 0.0831 | 0.121 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0041 | 0.0365 | 0.1227 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0071 | 0.0831 | 0.145 |
Trichomonas vaginalis | esterase, putative | 0.0055 | 0.0583 | 0.2453 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0019 | 0.0014 | 0.002 |
Schistosoma mansoni | ferritin light chain | 0.0025 | 0.0106 | 0.0106 |
Schistosoma mansoni | tar DNA-binding protein | 0.0047 | 0.0454 | 0.0454 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0071 | 0.0831 | 0.145 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0041 | 0.0365 | 0.1227 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0071 | 0.0831 | 0.145 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.018 | 0.2517 | 0.3661 |
Plasmodium falciparum | thioredoxin reductase | 0.0071 | 0.0831 | 0.2828 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0201 | 0.0231 |
Schistosoma mansoni | hypothetical protein | 0.0388 | 0.5765 | 0.5765 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0041 | 0.0365 | 0.1227 |
Schistosoma mansoni | tar DNA-binding protein | 0.0047 | 0.0454 | 0.0454 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0055 | 0.0583 | 0.0681 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.018 | 0.2517 | 0.2936 |
Echinococcus granulosus | Smad4 | 0.0035 | 0.0257 | 0.0368 |
Echinococcus granulosus | Ankyrin | 0.0025 | 0.0104 | 0.0145 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0365 | 0.0422 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0494 | 0.0494 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.017 | 0.2365 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0037 | 0.0294 | 0.0294 |
Brugia malayi | Cell death protein 3 precursor | 0.0061 | 0.0668 | 0.078 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0056 | 0.0595 | 0.0595 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0104 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0101 | 0.0113 |
Echinococcus multilocularis | zinc finger protein | 0.0054 | 0.0554 | 0.0806 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0019 | 0.0014 | 0.0042 |
Echinococcus multilocularis | expressed protein | 0.0025 | 0.0106 | 0.0155 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0568 | 0.8563 | 1 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0019 | 0.0014 | 0.0018 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0522 | 0.7859 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0071 | 0.0831 | 0.2828 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0072 | 0.0841 | 0.2862 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0025 | 0.0106 | 0.0118 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0055 | 0.0583 | 0.0726 |
Plasmodium vivax | ferrodoxin reductase, putative | 0.0019 | 0.0014 | 0.0048 |
Brugia malayi | Bromodomain containing protein | 0.0097 | 0.1229 | 0.1435 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0041 | 0.0365 | 0.0632 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0019 | 0.0014 | 0.0048 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0025 | 0.0106 | 0.0118 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0041 | 0.0365 | 0.0447 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0031 | 0.0201 | 0.0675 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0019 | 0.0014 | 0.002 |
Echinococcus multilocularis | caspase 2 | 0.0061 | 0.0668 | 0.0973 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0071 | 0.0831 | 0.145 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0016 | 0.0014 |
Brugia malayi | MH1 domain containing protein | 0.0019 | 0.0016 | 0.0019 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0035 | 0.0257 | 0.0257 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0071 | 0.0831 | 0.145 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0209 | 0.2972 | 0.4324 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0055 | 0.0583 | 0.2453 |
Schistosoma mansoni | Smad4 | 0.0035 | 0.0257 | 0.0257 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0018 | 0.0004 | 0.0006 |
Echinococcus granulosus | smad | 0.0035 | 0.0257 | 0.0368 |
Schistosoma mansoni | cpg binding protein | 0.0039 | 0.0321 | 0.0321 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0061 | 0.0668 | 0.3558 |
Trypanosoma cruzi | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0019 | 0.0014 | 0.0018 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0019 | 0.0014 | 0.0018 |
Echinococcus multilocularis | smad | 0.0035 | 0.0257 | 0.0374 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0071 | 0.0831 | 0.145 |
Brugia malayi | hypothetical protein | 0.0043 | 0.0383 | 0.0447 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0019 | 0.0014 | 0.0042 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0071 | 0.0831 | 0.2838 |
Schistosoma mansoni | netrin receptor unc5 | 0.0025 | 0.0101 | 0.0101 |
Echinococcus multilocularis | ferritin | 0.0025 | 0.0106 | 0.0155 |
Loa Loa (eye worm) | glutathione reductase | 0.0206 | 0.2929 | 0.3417 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0031 | 0.0201 | 0.0655 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.0221 | 0.0258 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0206 | 0.2929 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0041 | 0.0365 | 0.1227 |
Plasmodium vivax | hypothetical protein, conserved | 0.0018 | 0.0004 | 0.0014 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0083 | 0.1012 | 0.1272 |
Leishmania major | NADH dehydrogenase, putative | 0.0019 | 0.0014 | 0.0018 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0018 | 0.0004 | 0.0014 |
Schistosoma mansoni | smad1 5 8 and | 0.0035 | 0.0257 | 0.0257 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.017 | 0.2365 | 1 |
Schistosoma mansoni | smad | 0.0035 | 0.0257 | 0.0257 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.017 | 0.2365 | 1 |
Plasmodium falciparum | type II NADH:ubiquinone oxidoreductase | 0.0019 | 0.0014 | 0.0034 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0056 | 0.0595 | 0.0866 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0025 | 0.0101 | 0.0101 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0568 | 0.8563 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0055 | 0.0583 | 0.0583 |
Mycobacterium ulcerans | hypothetical protein | 0.0203 | 0.2874 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0055 | 0.0583 | 0.0726 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0071 | 0.0831 | 0.2838 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0056 | 0.0595 | 0.0861 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.0019 | 0.0014 | 0.0048 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0222 | 0.0222 |
Loa Loa (eye worm) | nuclear factor I | 0.0019 | 0.0016 | 0.0014 |
Onchocerca volvulus | 0.0055 | 0.0583 | 0.3106 | |
Echinococcus granulosus | expressed protein | 0.0025 | 0.0106 | 0.0149 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0019 | 0.0014 | 0.0015 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0025 | 0.0104 | 0.0104 |
Leishmania major | hypothetical protein, conserved | 0.0072 | 0.0841 | 0.1467 |
Schistosoma mansoni | bromodomain containing protein | 0.0159 | 0.2196 | 0.2196 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.018 | 0.2517 | 0.3665 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0014 | 0.0012 |
Brugia malayi | Death domain containing protein | 0.0025 | 0.0101 | 0.0117 |
Brugia malayi | AMP-binding enzyme family protein | 0.0041 | 0.0365 | 0.0426 |
Schistosoma mansoni | cpg binding protein | 0.0039 | 0.0321 | 0.0321 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0041 | 0.0365 | 0.1492 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.132 | 0.1538 |
Brugia malayi | hypothetical protein | 0.0072 | 0.0841 | 0.0982 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0126 | 0.1675 | 0.2439 |
Brugia malayi | Protein kinase domain containing protein | 0.0025 | 0.0101 | 0.0117 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0294 | 0.0508 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0083 | 0.1012 | 0.1272 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0072 | 0.0841 | 0.2872 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0066 | 0.0745 | 0.1299 |
Schistosoma mansoni | ferritin | 0.0025 | 0.0106 | 0.0106 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0041 | 0.0365 | 0.1492 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.017 | 0.2365 | 1 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0019 | 0.0014 | 0.0016 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.006 | 0.0653 | 0.2749 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0018 | 0.0004 | 0.0004 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0041 | 0.0365 | 0.1227 |
Mycobacterium tuberculosis | Probable reductase | 0.047 | 0.7042 | 0.8958 |
Schistosoma mansoni | tar DNA-binding protein | 0.0047 | 0.0454 | 0.0454 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0175 | 0.0205 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.047 | 0.7042 | 0.8958 |
Brugia malayi | AMP-binding enzyme family protein | 0.0041 | 0.0365 | 0.0426 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.019 | 0.2683 | 0.3906 |
Brugia malayi | AMP-binding enzyme family protein | 0.0041 | 0.0365 | 0.0426 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0055 | 0.0583 | 0.0726 |
Loa Loa (eye worm) | RNA binding protein | 0.0047 | 0.0454 | 0.0526 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0071 | 0.0831 | 0.2828 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0019 | 0.0014 | 0.0016 |
Trichomonas vaginalis | set domain proteins, putative | 0.0138 | 0.1875 | 0.7922 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0018 | 0.0004 | 0.0014 |
Brugia malayi | TAR-binding protein | 0.0047 | 0.0454 | 0.053 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0201 | 0.0231 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0019 | 0.0014 | 0.0018 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0071 | 0.0831 | 0.145 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0041 | 0.036 | 0.0524 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0072 | 0.0841 | 0.2872 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0059 | 0.0641 | 0.0641 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0019 | 0.0014 | 0.0048 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0071 | 0.0831 | 0.145 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0025 | 0.0106 | 0.0118 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0059 | 0.0641 | 0.0641 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.018 | 0.2517 | 0.3661 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0041 | 0.0365 | 0.0447 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0071 | 0.0831 | 0.2838 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0522 | 0.7859 | 1 |
Echinococcus multilocularis | caspase 8 | 0.0018 | 0.0004 | 0.0006 |
Leishmania major | trypanothione reductase | 0.0206 | 0.2929 | 0.5127 |
Toxoplasma gondii | selenide, water dikinase | 0.0019 | 0.0014 | 0.0048 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0069 | 0.0793 | 0.0793 |
Mycobacterium tuberculosis | Conserved protein | 0.0055 | 0.0583 | 0.0726 |
Brugia malayi | MH1 domain containing protein | 0.0035 | 0.0257 | 0.03 |
Leishmania major | hypothetical protein, conserved | 0.0019 | 0.0014 | 0.0018 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0019 | 0.0014 | 0.0012 |
Leishmania major | hypothetical protein, conserved | 0.0055 | 0.0583 | 0.1015 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0041 | 0.036 | 0.0518 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0365 | 0.0422 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0055 | 0.0583 | 0.1015 |
Echinococcus granulosus | cpg binding protein | 0.0039 | 0.0321 | 0.0462 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0035 | 0.0257 | 0.0368 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0025 | 0.0101 | 0.0141 |
Trichomonas vaginalis | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0014 | 0.0042 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0025 | 0.0101 | 0.0146 |
Schistosoma mansoni | smad1 5 8 and | 0.0035 | 0.0257 | 0.0257 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0047 | 0.0454 | 0.0526 |
Toxoplasma gondii | ABC1 family protein | 0.0055 | 0.0583 | 0.1991 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0055 | 0.0583 | 0.0726 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.047 | 0.7042 | 0.8958 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.017 | 0.2365 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0019 | 0.0014 | 0.0018 |
Plasmodium vivax | glutathione reductase, putative | 0.0206 | 0.2929 | 1 |
Echinococcus granulosus | caspase 2 | 0.0061 | 0.0668 | 0.0968 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.006 | 0.0653 | 0.223 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.005 | 0.0494 | 0.204 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0206 | 0.2929 | 0.3716 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0032 | 0.0222 | 0.0323 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.018 | 0.2517 | 0.294 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0365 | 0.0422 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0055 | 0.0583 | 0.2453 |
Echinococcus multilocularis | Smad4 | 0.0035 | 0.0257 | 0.0374 |
Brugia malayi | Smad1 | 0.0035 | 0.0257 | 0.03 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.019 | 0.2683 | 0.2683 |
Brugia malayi | hypothetical protein | 0.0047 | 0.0443 | 0.0518 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.015 | 0.2062 | 0.3002 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2377 | 0.2773 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0354 | 0.5242 | 0.6664 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0071 | 0.0831 | 0.3475 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0019 | 0.0014 | 0.0042 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0047 | 0.0453 | 0.0525 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.015 | 0.2062 | 0.2998 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0507 | 0.7617 | 0.8895 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0568 | 0.8563 | 1 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0019 | 0.0014 | 0.002 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0384 | 0.5709 | 1 |
Onchocerca volvulus | 0.0139 | 0.1878 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0294 | 0.0294 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.047 | 0.7042 | 0.8958 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0019 | 0.0014 | 0.0015 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0019 | 0.0014 | 0.002 |
Onchocerca volvulus | 0.0041 | 0.0365 | 0.1943 | |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.047 | 0.7042 | 0.8958 |
Treponema pallidum | NADH oxidase | 0.0071 | 0.0831 | 0.3475 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.2517 | 0.2517 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.047 | 0.7042 | 0.8958 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase-like protein, putative | 0.0019 | 0.0014 | 0.0018 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.0018 | 0.0004 | 0.0004 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0019 | 0.0014 | 0.0042 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0031 | 0.0201 | 0.0239 |
Schistosoma mansoni | zinc finger protein | 0.0054 | 0.0554 | 0.0554 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0071 | 0.0831 | 0.145 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0182 | 0.2554 | 0.4469 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0175 | 0.0205 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0019 | 0.0014 | 0.0048 |
Trypanosoma brucei | trypanothione reductase | 0.0206 | 0.2929 | 0.5127 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0522 | 0.7859 | 1 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.0025 | 0.0106 | 0.0323 |
Trichomonas vaginalis | ferritin, putative | 0.0025 | 0.0106 | 0.0434 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0072 | 0.0839 | 0.2865 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.0043 | 0.0383 | 0.0558 |
Brugia malayi | PHD-finger family protein | 0.0066 | 0.0754 | 0.0881 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0019 | 0.0014 | 0.0042 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0019 | 0.0014 | 0.0015 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0019 | 0.0014 | 0.0042 |
Schistosoma mansoni | glutamate synthase | 0.0019 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | beta-lactamase | 0.0055 | 0.0583 | 0.0677 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.017 | 0.2365 | 1 |
Echinococcus granulosus | glutamate synthase | 0.0019 | 0.0014 | 0.0015 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0209 | 0.2972 | 0.4327 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0071 | 0.0831 | 0.145 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.006 | 0.0653 | 0.223 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0388 | 0.5765 | 0.6732 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0055 | 0.0583 | 0.0726 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.2517 | 0.2517 |
Schistosoma mansoni | sulfide quinone reductase | 0.0019 | 0.0014 | 0.0014 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0041 | 0.0365 | 0.1227 |
Schistosoma mansoni | apoferritin-2 | 0.0025 | 0.0106 | 0.0106 |
Plasmodium falciparum | glutathione reductase | 0.0206 | 0.2929 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0459 | 0.6868 | 0.6868 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0175 | 0.0205 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0032 | 0.0222 | 0.0318 |
Loa Loa (eye worm) | TAR-binding protein | 0.0047 | 0.0454 | 0.0526 |
Onchocerca volvulus | 0.0019 | 0.0014 | 0.0075 | |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0025 | 0.0106 | 0.1132 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0025 | 0.0101 | 0.0141 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.005 | 0.0494 | 0.1674 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0019 | 0.0014 | 0.0016 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0507 | 0.7617 | 0.8895 |
Plasmodium falciparum | ferrodoxin reductase-like protein | 0.0019 | 0.0014 | 0.0034 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0055 | 0.0583 | 0.199 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0019 | 0.0014 | 0.0015 |
Mycobacterium ulcerans | hypothetical protein | 0.0041 | 0.0365 | 0.1227 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0071 | 0.0831 | 0.0831 |
Schistosoma mansoni | smad1 5 8 and | 0.0035 | 0.0257 | 0.0257 |
Trypanosoma brucei | NADH dehydrogenase | 0.0019 | 0.0014 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0841 | 0.0978 |
Schistosoma mansoni | ferritin light chain | 0.0025 | 0.0106 | 0.0106 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0383 | 0.0383 |
Schistosoma mansoni | ferritin | 0.0025 | 0.0106 | 0.0106 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.017 | 0.2365 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.017 | 0.2365 | 1 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0018 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0122 | 0.1614 | 0.1881 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.0043 | 0.0383 | 0.0552 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0055 | 0.0583 | 0.2453 |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.0025 | 0.0106 | 0.0323 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0055 | 0.0583 | 0.2453 |
Schistosoma mansoni | tar DNA-binding protein | 0.0047 | 0.0454 | 0.0454 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0522 | 0.7859 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0507 | 0.7617 | 0.8895 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0201 | 0.0231 |
Mycobacterium ulcerans | lipase LipD | 0.0055 | 0.0583 | 0.199 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0071 | 0.0831 | 0.2857 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0201 | 0.0231 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0019 | 0.0014 | 0.0014 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0459 | 0.6868 | 1 |
Schistosoma mansoni | sulfide quinone reductase | 0.0019 | 0.0014 | 0.0014 |
Plasmodium falciparum | NAD(P)H-dependent glutamate synthase, putative | 0.0019 | 0.0014 | 0.0034 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0072 | 0.0841 | 0.2862 |
Loa Loa (eye worm) | PHD-finger family protein | 0.005 | 0.0494 | 0.0573 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.017 | 0.2365 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (ADMET) | = 33 ug ml-1 | Cytotoxicity against HEL cells assessed as reduction of cell growth after 3 days | ChEMBL. | 17869124 |
CC50 (ADMET) | = 33 ug ml-1 | Cytotoxicity against HEL cells assessed as reduction of cell growth after 3 days | ChEMBL. | 17869124 |
EC50 (functional) | > 4 ug ml-1 | Antiviral activity against TK+ VZV OKA in HEL cells assessed as reduction of virus plaque formation | ChEMBL. | 17869124 |
EC50 (functional) | > 4 ug ml-1 | Antiviral activity against TK- VZV 07/1 in HEL cells assessed as reduction of virus plaque formation | ChEMBL. | 17869124 |
EC50 (functional) | > 4 ug ml-1 | Antiviral activity against HCMV AD169 in HEL cells assessed as reduction of virus plaque formation after 5 days | ChEMBL. | 17869124 |
EC50 (functional) | > 4 ug ml-1 | Antiviral activity against HCMV Davis in HEL cells assessed as reduction of virus plaque formation after 5 days | ChEMBL. | 17869124 |
MCC (ADMET) | = 20 ug ml-1 | Cytotoxicity against HEL cells assessed as alteration in cell morphology after 3 days | ChEMBL. | 17869124 |
MCC (ADMET) | = 20 ug ml-1 | Cytotoxicity against HEL cells assessed as alteration in cell morphology after 3 days | ChEMBL. | 17869124 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.