Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0123 | 0.3262 | 0.4454 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.026 | 0.7302 | 1 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0012 | 0.0018 | 0.0004 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.026 | 0.7302 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0123 | 0.3262 | 0.4454 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0128 | 0.0176 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0128 | 0.3817 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.002 | 0.0249 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.026 | 0.7302 | 0.7298 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3262 | 0.3253 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3262 | 0.3253 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.003 | 0.0548 | 0.0535 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.002 | 0.0249 | 0.0317 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0128 | 0.0111 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0427 | 0.0585 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.003 | 0.0548 | 0.0531 |
Onchocerca volvulus | 0.026 | 0.7302 | 0.7298 | |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0123 | 0.3262 | 0.325 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0012 | 0.0018 | 0.0024 |
Entamoeba histolytica | protein kinase 2, putative | 0.002 | 0.0249 | 0.3919 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.026 | 0.7302 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0123 | 0.3262 | 0.4467 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0017 | 0.0164 | 0.0201 |
Giardia lamblia | Kinase, AGC PKA | 0.002 | 0.0249 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.026 | 0.7302 | 0.7298 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0017 | 0.0164 | 0.0151 |
Trichomonas vaginalis | AGC family protein kinase | 0.0032 | 0.0607 | 0.0875 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.026 | 0.7302 | 0.7298 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3262 | 0.3253 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0123 | 0.3262 | 0.4454 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0427 | 0.0562 |
Brugia malayi | nuclear receptor RXR | 0.0137 | 0.3695 | 0.3684 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0123 | 0.3262 | 0.325 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0128 | 0.0151 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0017 | 0.0164 | 0.0201 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0022 | 0.0307 | 0.0421 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0427 | 0.0414 |
Loa Loa (eye worm) | hypothetical protein | 0.026 | 0.7302 | 0.7299 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.3695 | 0.3686 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0427 | 0.0414 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.026 | 0.7302 | 1 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0017 | 0.0164 | 0.0201 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.026 | 0.7302 | 1 |
Brugia malayi | ecdysteroid receptor | 0.026 | 0.7302 | 0.7298 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.026 | 0.7302 | 0.7298 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0018 | 0.0004 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0012 | 0.0018 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3262 | 0.3253 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0427 | 0.0562 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0017 | 0.0164 | 0.0224 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0022 | 0.0307 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0018 | 0.0004 |
Trichomonas vaginalis | AGC family protein kinase | 0.0012 | 0.002 | 0.0003 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.026 | 0.7302 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0137 | 0.3695 | 0.3684 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3262 | 0.3253 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.002 | 0.0242 | 0.0308 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0123 | 0.3262 | 0.4454 |
Trichomonas vaginalis | AGC family protein kinase | 0.0032 | 0.0607 | 0.0875 |
Entamoeba histolytica | protein kinase, putative | 0.0032 | 0.0607 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.055 | 0.073 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0427 | 0.0562 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.055 | 0.073 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0128 | 0.0152 |
Brugia malayi | hypothetical protein | 0.0137 | 0.3695 | 0.3684 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.002 | 0.0242 | 0.0308 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0017 | 0.0164 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3262 | 0.3253 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.055 | 0.073 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0123 | 0.3262 | 0.4454 |
Onchocerca volvulus | 0.0123 | 0.3262 | 0.325 | |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.002 | 0.0249 | 0.0317 |
Schistosoma mansoni | thyroid hormone receptor | 0.026 | 0.7302 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0123 | 0.3262 | 0.325 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0123 | 0.3262 | 0.325 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.026 | 0.7302 | 1 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0017 | 0.0164 | 0.0201 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0352 | 1 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0517 | 0.0685 |
Brugia malayi | nuclear hormone receptor | 0.0123 | 0.3262 | 0.325 |
Onchocerca volvulus | 0.0242 | 0.6755 | 0.6749 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.055 | 0.0753 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.026 | 0.7302 | 0.7298 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.026 | 0.7302 | 0.7298 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.026 | 0.7302 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.026 | 0.7302 | 0.7298 |
Schistosoma mansoni | nuclear hormone receptor | 0.0123 | 0.3262 | 0.4467 |
Schistosoma mansoni | zinc finger protein | 0.0123 | 0.3262 | 0.4467 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0123 | 0.3262 | 0.4454 |
Brugia malayi | tailless protein | 0.0123 | 0.3262 | 0.325 |
Schistosoma mansoni | dep domain containing protein | 0.0017 | 0.0164 | 0.0224 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.002 | 0.0242 | 0.0308 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.026 | 0.7302 | 0.7298 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0676 | 0.0664 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.026 | 0.7302 | 0.7298 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0017 | 0.0164 | 0.0151 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0128 | 0.0114 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.026 | 0.7302 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0128 | 0.0151 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.0128 | 0.3817 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.026 | 0.7302 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0032 | 0.0607 | 0.0875 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0427 | 0.041 |
Echinococcus granulosus | nervana 2 | 0.002 | 0.0242 | 0.0308 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0164 | 0.0151 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.002 | 0.0249 | 0.0317 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.1137 | 0.1557 |
Brugia malayi | nuclear receptor NHR-67 | 0.0123 | 0.3262 | 0.325 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.3695 | 0.3686 |
Brugia malayi | hypothetical protein | 0.0123 | 0.3262 | 0.325 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.026 | 0.7302 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0032 | 0.0607 | 1 |
Onchocerca volvulus | 0.0017 | 0.0164 | 0.0146 | |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.1149 | 0.1133 |
Onchocerca volvulus | 0.003 | 0.055 | 0.0533 | |
Onchocerca volvulus | Bile acid receptor homolog | 0.026 | 0.7302 | 0.7298 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.4734 | 0.6482 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.026 | 0.7302 | 0.7299 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.055 | 0.0753 |
Brugia malayi | nuclear hormone receptor | 0.026 | 0.7302 | 0.7298 |
Loa Loa (eye worm) | hypothetical protein | 0.026 | 0.7302 | 0.7299 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0022 | 0.0307 | 0.4916 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0017 | 0.0164 | 0.0146 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0016 | 0.0128 | 0.5 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0028 | 0.0014 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0164 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.026 | 0.7302 | 0.7299 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0676 | 0.0926 |
Toxoplasma gondii | AGC kinase | 0.003 | 0.0548 | 0.997 |
Echinococcus granulosus | nervana 2 | 0.002 | 0.0242 | 0.0308 |
Loa Loa (eye worm) | hypothetical protein | 0.026 | 0.7302 | 0.7299 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.026 | 0.7302 | 0.7299 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0427 | 0.0414 |
Brugia malayi | conserved hypotetical protein | 0.0123 | 0.3262 | 0.325 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3262 | 0.3253 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0128 | 0.0111 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0137 | 0.3695 | 0.506 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0128 | 0.0152 |
Trypanosoma cruzi | Protein kinase B | 0.0022 | 0.0307 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.003 | 0.0548 | 0.9002 |
Onchocerca volvulus | 0.0026 | 0.0427 | 0.041 | |
Echinococcus multilocularis | nervana 2 | 0.002 | 0.0242 | 0.0308 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0012 | 0.0018 | 0.0004 |
Schistosoma mansoni | lamin | 0.0026 | 0.0427 | 0.0585 |
Trichomonas vaginalis | AGC family protein kinase | 0.0032 | 0.0607 | 0.0875 |
Schistosoma mansoni | lamin | 0.0026 | 0.0427 | 0.0585 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0123 | 0.3262 | 0.4454 |
Loa Loa (eye worm) | DR-78 | 0.0123 | 0.3262 | 0.3253 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0128 | 0.011 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0017 | 0.0164 | 0.0146 |
Brugia malayi | nuclear receptor NHR-88 | 0.026 | 0.7302 | 0.7298 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3262 | 0.3253 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0128 | 0.0115 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0123 | 0.3262 | 0.4454 |
Brugia malayi | nuclear receptor NHR-88 | 0.0123 | 0.3262 | 0.325 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.026 | 0.7302 | 0.7298 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0128 | 0.0175 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.026 | 0.7302 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0128 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3262 | 0.3253 |
Schistosoma mansoni | ras GTP exchange factor | 0.0012 | 0.0018 | 0.0024 |
Brugia malayi | Pre-SET motif family protein | 0.0212 | 0.5893 | 0.5886 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.4734 | 0.6482 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.055 | 0.0537 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0022 | 0.0307 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.026 | 0.7302 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0123 | 0.3262 | 0.325 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.055 | 0.0753 |
Loa Loa (eye worm) | hypothetical protein | 0.0352 | 1 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.055 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.055 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3262 | 0.3253 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0128 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.3695 | 0.3686 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.026 | 0.7302 | 0.7299 |
Brugia malayi | Protein kinase domain containing protein | 0.0032 | 0.0607 | 0.059 |
Schistosoma mansoni | nuclear receptor | 0.0123 | 0.3262 | 0.4467 |
Onchocerca volvulus | 0.0026 | 0.0427 | 0.041 | |
Onchocerca volvulus | 0.0123 | 0.3262 | 0.325 | |
Schistosoma mansoni | retinoic acid receptor RXR | 0.026 | 0.7302 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0069 | 0.0055 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0123 | 0.3262 | 0.4467 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.1149 | 0.1133 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0164 | 0.0146 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0123 | 0.3262 | 0.4454 |
Schistosoma mansoni | coup transcription factor | 0.026 | 0.7302 | 1 |
Schistosoma mansoni | regulator of G protein signaling | 0.0017 | 0.0164 | 0.0224 |
Schistosoma mansoni | nuclear hormone receptor | 0.0123 | 0.3262 | 0.4467 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.026 | 0.7302 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0128 | 0.0151 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.002 | 0.0249 | 0.2858 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0137 | 0.3695 | 0.5048 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0017 | 0.0164 | 0.0224 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0123 | 0.3262 | 0.4467 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0123 | 0.3262 | 0.325 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0128 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3262 | 0.3253 |
Trichomonas vaginalis | AGC family protein kinase | 0.0032 | 0.0607 | 0.0875 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0128 | 0.0151 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.026 | 0.7302 | 0.7298 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0032 | 0.0607 | 0.0594 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0123 | 0.3262 | 0.325 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.026 | 0.7302 | 0.7299 |
Brugia malayi | ecdysone receptor | 0.0123 | 0.3262 | 0.325 |
Echinococcus granulosus | lamin | 0.0026 | 0.0427 | 0.0562 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.026 | 0.7302 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0128 | 0.0151 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0022 | 0.0307 | 0.4916 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0128 | 0.0175 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0128 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.3695 | 0.3686 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3262 | 0.3253 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0137 | 0.3695 | 0.3686 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0028 | 0.0014 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0123 | 0.3262 | 0.4454 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0012 | 0.0018 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3262 | 0.3253 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1149 | 0.1137 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0128 | 0.0152 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0137 | 0.3695 | 0.5048 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.026 | 0.7302 | 0.7299 |
Trichomonas vaginalis | AGC family protein kinase | 0.0032 | 0.0607 | 0.0875 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0128 | 0.0175 |
Brugia malayi | steroid hormone receptor | 0.026 | 0.7302 | 0.7298 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0128 | 0.011 |
Toxoplasma gondii | hypothetical protein | 0.0017 | 0.0164 | 0.0845 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0017 | 0.0164 | 0.0201 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0137 | 0.3695 | 0.3684 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.026 | 0.7302 | 0.7298 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0137 | 0.3695 | 0.506 |
Echinococcus granulosus | FTZ F1 alpha | 0.026 | 0.7302 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.026 | 0.7302 | 1 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0128 | 0.0152 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.026 | 0.7302 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.026 | 0.7302 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0028 | 0.0014 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.026 | 0.7302 | 0.7299 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.026 | 0.7302 | 0.7299 |
Schistosoma mansoni | nuclear receptor | 0.0123 | 0.3262 | 0.4467 |
Echinococcus multilocularis | nervana 2 | 0.002 | 0.0242 | 0.0308 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.026 | 0.7302 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0123 | 0.3262 | 0.4454 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.026 | 0.7302 | 0.7298 |
Loa Loa (eye worm) | hypothetical protein | 0.026 | 0.7302 | 0.7299 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0022 | 0.0307 | 0.0398 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0069 | 0.0051 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.026 | 0.7302 | 0.7298 |
Schistosoma mansoni | dishevelled | 0.0017 | 0.0164 | 0.0224 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.002 | 0.0249 | 0.7971 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0022 | 0.0307 | 0.0398 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0676 | 0.066 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.026 | 0.7302 | 1 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0032 | 0.0607 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0242 | 0.6755 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.026 | 0.7302 | 1 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0017 | 0.0164 | 0.0201 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0012 | 0.0018 | 0.0024 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0427 | 0.0562 |
Loa Loa (eye worm) | hypothetical protein | 0.026 | 0.7302 | 0.7299 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0128 | 0.0175 |
Brugia malayi | hypothetical protein | 0.0137 | 0.3695 | 0.3684 |
Loa Loa (eye worm) | hypothetical protein | 0.026 | 0.7302 | 0.7299 |
Schistosoma mansoni | thyroid hormone receptor | 0.026 | 0.7302 | 1 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0017 | 0.0164 | 0.0201 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0123 | 0.3262 | 0.4454 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.026 | 0.7302 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.055 | 0.0753 |
Schistosoma mansoni | guanine-nucleotide-exchange-factor | 0.0012 | 0.0018 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0164 | 0.0151 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0123 | 0.3262 | 0.325 |
Schistosoma mansoni | nuclear hormone receptor | 0.026 | 0.7302 | 1 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0017 | 0.0164 | 0.0146 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0212 | 0.5893 | 0.5887 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0123 | 0.3262 | 0.3253 |
Echinococcus multilocularis | geminin | 0.0173 | 0.4734 | 0.6474 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0164 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.3695 | 0.3686 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0413 | 0.04 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0427 | 0.041 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.026 | 0.7302 | 1 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0017 | 0.0164 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.026 | 0.7302 | 0.7299 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.055 | 0.0533 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0123 | 0.3262 | 0.325 |
Loa Loa (eye worm) | steroid hormone receptor | 0.026 | 0.7302 | 0.7299 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0123 | 0.3262 | 0.3253 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0017 | 0.0164 | 0.0201 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.026 | 0.7302 | 0.7298 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.1149 | 0.1137 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0123 | 0.3262 | 0.3253 |
Brugia malayi | DIX domain containing protein | 0.0017 | 0.0164 | 0.0146 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0427 | 0.0562 |
Echinococcus granulosus | geminin | 0.0173 | 0.4734 | 0.6474 |
Brugia malayi | hypothetical protein | 0.0123 | 0.3262 | 0.325 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.026 | 0.7302 | 0.7298 |
Trichomonas vaginalis | AGC family protein kinase | 0.0032 | 0.0607 | 0.0875 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.026 | 0.7302 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.026 | 0.7302 | 0.7298 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.002 | 0.0242 | 0.0308 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0128 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.026 | 0.7302 | 0.7298 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.026 | 0.7302 | 1 |
Schistosoma mansoni | dishevelled | 0.0017 | 0.0164 | 0.0224 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0017 | 0.0164 | 0.0201 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 100 uM | Inhibition of HCV NS5B RdRp | ChEMBL. | 17258458 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.