Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | malonyl-CoA decarboxylase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | malonyl-CoA decarboxylase, mitochondrial precursor, putative | 0.0198 | 0 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.108 | 0.5957 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1604 | 0.9498 | 0.9928 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.1612 | 0.9552 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.1164 | 0.6523 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.1164 | 0.6523 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | malonyl-CoA decarboxylase | 0.0504 | 0.2067 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.108 | 0.5957 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.108 | 0.5957 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.1612 | 0.9552 | 0.9435 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0939 | 0.5007 | 0.5 |
Leishmania major | malonyl-coa decarboxylase-like protein | 0.0198 | 0 | 0.5 |
Trypanosoma cruzi | malonyl-CoA decarboxylase, mitochondrial precursor, putative | 0.0198 | 0 | 0.5 |
Trypanosoma cruzi | malonyl-CoA decarboxylase, mitochondrial precursor, putative | 0.0198 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.1612 | 0.9552 | 0.9435 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.