Detailed information for compound 453419

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 393.439 | Formula: C21H23N5O3
  • H donors: 1 H acceptors: 4 LogP: 3.06 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc2c(c1)cncc2Cc1[nH]c2c(n1)n(CC(C)C)c(=O)n(c2=O)C
  • InChi: 1S/C21H23N5O3/c1-12(2)11-26-19-18(20(27)25(3)21(26)28)23-17(24-19)8-14-10-22-9-13-7-15(29-4)5-6-16(13)14/h5-7,9-10,12H,8,11H2,1-4H3,(H,23,24)
  • InChiKey: GFNFAFKKZDVOOR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens phosphodiesterase 5A, cGMP-specific Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Schistosoma japonicum Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Leishmania braziliensis cAMP specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trypanosoma cruzi cAMP specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trypanosoma brucei cAMP-specific phosphodiesterase Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Schistosoma japonicum Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11, putative Get druggable targets OG5_127318 All targets in OG5_127318
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trypanosoma cruzi cAMP specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Candida albicans similar to S. cerevisiae PDE2 (YOR360C) cAMP phosphodiesterase Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trypanosoma congolense cAMP-specific phosphodiesterase Get druggable targets OG5_127318 All targets in OG5_127318
Trypanosoma brucei cAMP-specific phosphodiesterase Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase Get druggable targets OG5_127318 All targets in OG5_127318
Leishmania infantum cAMP specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trypanosoma congolense cAMP-specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trypanosoma brucei gambiense cAMP-specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Leishmania donovani cAMP specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Leishmania mexicana cAMP specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trypanosoma cruzi cAMP specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Candida albicans similar to S. cerevisiae PDE2 (YOR360C) cAMP phosphodiesterase Get druggable targets OG5_127318 All targets in OG5_127318
Schistosoma japonicum expressed protein Get druggable targets OG5_127318 All targets in OG5_127318
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Leishmania braziliensis cAMP specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Leishmania mexicana cAMP specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trypanosoma brucei gambiense cAMP-specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Leishmania infantum cAMP specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Schistosoma japonicum Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127318 All targets in OG5_127318
Toxoplasma gondii hypothetical protein Get druggable targets OG5_127318 All targets in OG5_127318
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
Trypanosoma cruzi cAMP specific phosphodiesterase, putative Get druggable targets OG5_127318 All targets in OG5_127318
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major hypothetical protein, conserved 0.0221 0.1455 0.295
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Brugia malayi calpain family protein 1 0.0227 0.1502 0.8871
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0093 0.0538 0.1055
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0057 0.028 0.0242
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0057 0.028 0.0242
Entamoeba histolytica cysteine proteinase, putative 0.0083 0.047 0.2614
Leishmania major calpain family cysteine protease-like protein 0.0457 0.315 0.659
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.023 0.1524 0.3126
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0161 0.1027 0.2096
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0057 0.028 0.0242
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0033 0.011 0.0559
Giardia lamblia Cathepsin B precursor 0.0033 0.011 0.0736
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Echinococcus granulosus cathepsin b 0.0084 0.0475 0.2174
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0029 0.008 0.0434
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0037 0.0141 0.0806
Trypanosoma cruzi cysteine proteinase, putative 0.0083 0.047 0.091
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0033 0.0106 0.0575
Loa Loa (eye worm) hypothetical protein 0.0037 0.0141 0.0604
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0028 0.0077 0.0044
Entamoeba histolytica cysteine protease, putative 0.0033 0.011 0.0195
Leishmania major ATP-dependent phosphofructokinase 0.0054 0.0262 0.0389
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0103 0.0609 0.3301
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0068 0.0357 0.0632
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0679 0.4738 1
Mycobacterium ulcerans 6-phosphofructokinase 0.0054 0.0262 0.5317
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0401 0.2745 0.5754
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0037 0.0141 0.0604
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0057 0.028 0.0242
Trypanosoma cruzi otubain cysteine peptidase, Clan CA, family C65, putative 0.0071 0.038 0.0717
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0025 0.0052 0.0274
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0223 0.1472 0.3043
Trypanosoma cruzi otubain cysteine peptidase, Clan CA, family C65, putative 0.0071 0.038 0.0717
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Schistosoma mansoni cathepsin F (C01 family) 0.0157 0.0997 0.0962
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0063 0.0327 0.1429
Echinococcus granulosus ubiquitin specific peptidase c family 0.011 0.0659 0.3096
Trypanosoma brucei trypanothione synthetase, putative 0.0055 0.027 0.0447
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Echinococcus multilocularis jun protein 0.0028 0.0077 0.0044
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0087 0.0494 0.0457
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0065 0.0341 0.0559
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0395 0.2705 0.5653
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Brugia malayi bZIP transcription factor family protein 0.0028 0.0077 0.0268
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0037 0.0141 0.0102
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0041 0.0168 0.077
Echinococcus multilocularis calpain family protein 1, d 0.018 0.1163 0.1465
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0103 0.0609 0.0572
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0037 0.0141 0.0127
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0061 0.0311 0.1349
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.1455 0.3007
Plasmodium falciparum GPI-anchor transamidase, putative 0.005 0.0233 0.1553
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0763
Loa Loa (eye worm) ubiquitin C-terminal hydrolase UCH-L5 0.0093 0.0538 0.3014
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Giardia lamblia Cysteine protease 0.0033 0.011 0.0736
Echinococcus granulosus Peptidase C54 0.0068 0.0357 0.158
Loa Loa (eye worm) hypothetical protein 0.0037 0.0141 0.0604
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0068 0.0357 0.1936
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0215 0.1415 0.2895
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0084 0.0475 0.0438
Echinococcus granulosus cathepsin L cysteine protease 0.0083 0.047 0.2147
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0061 0.0311 0.0494
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0033 0.011 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.047 0.2547
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0054 0.0262 0.1421
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0192 0.1253 0.2577
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Brugia malayi cathepsin F-like cysteine proteinase 0.0033 0.011 0.0469
Loa Loa (eye worm) hypothetical protein 0.0033 0.011 0.0419
Entamoeba histolytica cysteine protease, putative 0.0083 0.047 0.2614
Echinococcus multilocularis calpain 7 (C02 family) 0.0253 0.169 0.2154
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0273 0.1831 0.3784
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0141 0.0653
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase isozyme L3, putative 0.0103 0.0609 0.3604
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0157 0.0997 0.7742
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0065 0.0341 0.0636
Toxoplasma gondii peptidase c13 family protein 0.005 0.0233 0.1553
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.006 0.03 0.1295
Trypanosoma cruzi trypanothione synthetase 0.0055 0.027 0.0485
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0037 0.0141 0.0762
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0221 0.1455 0.3007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Brugia malayi GPI-anchor transamidase 0.005 0.0233 0.121
Trichomonas vaginalis ubiquitin specific protease, putative 0.0037 0.0141 0.0762
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0157 0.0997 0.7742
Leishmania major hypothetical protein, conserved 0.0221 0.1455 0.295
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.011 0.0072
Giardia lamblia Cathepsin L precursor 0.0033 0.011 0.0736
Trypanosoma brucei kinesin, putative 0.0047 0.0213 0.0323
Echinococcus granulosus cysteine protease 0.0083 0.047 0.2147
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0068 0.0357 0.032
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Echinococcus multilocularis cathepsin L 0.0033 0.011 0.0087
Loa Loa (eye worm) hypothetical protein 0.0057 0.028 0.1446
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.005 0.0233 0.0326
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0157 0.0997 0.5407
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0468 0.3227 0.6782
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.011 0.0659 0.3571
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.013 0.0802 0.1549
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0331 0.2244 0.4688
Plasmodium falciparum serine repeat antigen 6 0.0033 0.011 0.0559
Leishmania major D-alanyl-glycyl endopeptidase-like protein,cysteine peptidase, Clan CA, family C51, putative 0.0257 0.1716 0.3511
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0157 0.0997 0.5407
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0218 0.1437 0.2941
Leishmania major hypothetical protein, conserved 0.0221 0.1455 0.295
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0227 0.1502 0.191
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma cruzi trypanothione synthetase-like protein, putative 0.0055 0.027 0.0485
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0029 0.008 0.0434
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Toxoplasma gondii cathepsin CPC2 0.0033 0.011 0.0559
Giardia lamblia Cathepsin B precursor 0.0033 0.011 0.0736
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0054 0.0262 0.0224
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.006 0.03 0.1616
Schistosoma mansoni cathepsin S (C01 family) 0.0033 0.011 0.0072
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0499 0.3448 0.7253
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0041 0.0223
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0037 0.0141 0.0806
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0033 0.011 0.0597
Echinococcus multilocularis cysteine protease 0.0157 0.0997 0.1249
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0196 0.1276 1
Loa Loa (eye worm) calpain D 0.0237 0.1568 0.9263
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0041 0.0168 0.0163
Onchocerca volvulus Cathepsin L homolog 0.0157 0.0997 1
Brugia malayi Cathepsin L-like precursor 0.005 0.0233 0.1207
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0299 0.2016 0.4203
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0273 0.1831 0.3784
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0157 0.0997 0.5407
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0033 0.011 0.0597
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0033 0.011 0.0438
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0037 0.0141 0.0127
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0227 0.1502 0.147
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0141 0.151
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0049 0.0224 0.1481
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0033 0.0106 0.0444
Trichomonas vaginalis conserved hypothetical protein 0.0275 0.1844 1
Brugia malayi calpain D 0.0237 0.1568 0.9267
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0083 0.0465 0.0863
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0037 0.0141 0.0492
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0037 0.0141 0.0492
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0037 0.0141 0.0127
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Plasmodium vivax serine-repeat antigen (SERA) 0.0033 0.011 0.0438
Loa Loa (eye worm) hypothetical protein 0.0037 0.0141 0.0604
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trichomonas vaginalis calpain, putative 0.018 0.1163 0.6304
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0443 0.3045 0.6364
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0041 0.0168 0.077
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0335 0.2275 0.4754
Brugia malayi hypothetical protein 0.0022 0.0033 0.0004
Toxoplasma gondii diphthine synthase, putative 0.0029 0.0081 0.0324
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0037 0.0141 0.0492
Giardia lamblia DUB-1 0.0037 0.0141 0.151
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0141 0.0632
Echinococcus granulosus cathepsin l1 0.0157 0.0997 0.4799
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0141 0.0653
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0443 0.3045 0.6394
Loa Loa (eye worm) hypothetical protein 0.0033 0.011 0.0419
Echinococcus granulosus calpain 5 0.0227 0.1502 0.7338
Echinococcus granulosus cysteine protease atg4b 0.0068 0.0357 0.158
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0679 0.4738 1
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0057 0.028 0.193
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0083 0.0465 0.2522
Echinococcus multilocularis cysteine protease 0.0157 0.0997 0.1249
Giardia lamblia Cathepsin B precursor 0.0084 0.0475 1
Loa Loa (eye worm) hypothetical protein 0.0157 0.0997 0.5801
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0221 0.1455 0.3007
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0033 0.011 0.0438
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.011 0.0659 0.1277
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.018 0.1163 0.6304
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0029 0.008 0.0042
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0148 0.0935 0.19
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0037 0.0141 0.0806
Brugia malayi calpain 5 0.0047 0.0213 0.1087
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0273 0.1831 0.3784
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0065 0.0341 0.1502
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0061 0.0311 0.1687
Toxoplasma gondii cathepsin CPC1 0.0033 0.011 0.0559
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0074 0.0401 0.0726
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0243 0.1616 0.3351
Onchocerca volvulus 0.0037 0.0141 0.1116
Giardia lamblia Cathepsin B precursor 0.0084 0.0475 1
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0037 0.0141 0.0762
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0057 0.028 0.0309
Echinococcus multilocularis PAB dependent poly(A) specific ribonuclease 0.0025 0.0054 0.0014
Entamoeba histolytica cysteine protease, putative 0.0083 0.047 0.2614
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0157 0.0997 0.5407
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0065 0.0341 0.039
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.005 0.0233 0.0367
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0103 0.0609 0.1133
Entamoeba histolytica cysteine protease, putative 0.0083 0.047 0.2614
Entamoeba histolytica hypothetical protein 0.0033 0.011 0.0195
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0141 0.0653
Echinococcus granulosus diphthine synthase 0.0029 0.0081 0.0193
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0382 0.2614 0.5477
Brugia malayi calpain 5 0.018 0.1163 0.6821
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.011 0.0597
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0336 0.1822
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0168 0.0911
Entamoeba histolytica hypothetical protein 0.0037 0.0141 0.04
Trypanosoma cruzi cysteine peptidase inhibitor 0.0193 0.1254 0.2579
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0074 0.0401 0.2174
Trypanosoma brucei unspecified product 0.0221 0.1455 0.2979
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0084 0.0475 0.0921
Plasmodium falciparum ubiquitin specific protease, putative 0.0037 0.0141 0.0806
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.011 0.0072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma cruzi cruzipain precursor, putative 0.005 0.0233 0.0404
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0037 0.0141 0.0102
Loa Loa (eye worm) hypothetical protein 0.018 0.1163 0.6804
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0157 0.0997 0.5407
Onchocerca volvulus 0.0037 0.0141 0.1116
Trichomonas vaginalis phosphofructokinase, putative 0.0054 0.0262 0.1422
Toxoplasma gondii cathepsin CPL 0.0157 0.0997 0.7742
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0061 0.0314 0.0276
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.018 0.1163 0.6304
Echinococcus multilocularis diphthine synthase 0.0029 0.0081 0.005
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0084 0.0475 0.0438
Entamoeba histolytica GPI-anchor transamidase, putative 0.005 0.0233 0.1021
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.005 0.0233 0.1263
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.018 0.1163 0.6304
Plasmodium falciparum plasmepsin VI 0.0057 0.028 0.193
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0157 0.0997 0.5407
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0037 0.0141 0.0102
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.018 0.1163 0.6304
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0037 0.0141 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0336 0.1822
Loa Loa (eye worm) hypothetical protein 0.005 0.0233 0.1161
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0141 0.0653
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0033 0.011 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Trypanosoma brucei calpain-like protein, putative 0.0243 0.1616 0.3324
Brugia malayi Papain family cysteine protease containing protein 0.0083 0.047 0.2639
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0037 0.0141 0.0127
Giardia lamblia Cathepsin L precursor 0.0033 0.011 0.0736
Trypanosoma brucei calpain-like protein, putative 0.0443 0.3045 0.6379
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.006 0.03 0.1646
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0679 0.4738 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0192 0.1253 0.2577
Toxoplasma gondii hypothetical protein 0.0037 0.0141 0.0806
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0093 0.0538 0.4022
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0067 0.0354 0.1837
Plasmodium falciparum serine repeat antigen 9 0.0033 0.011 0.0559
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0157 0.0997 0.5407
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0054 0.0262 0.0468
Brugia malayi Cathepsin L-like precursor 0.0157 0.0997 0.5823
Loa Loa (eye worm) calpain 5 0.0047 0.0213 0.104
Schistosoma mansoni cathepsin C 0.0033 0.011 0.0072
Echinococcus multilocularis ubiquitin specific protease 41 0.0065 0.0341 0.039
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0401 0.2174
Trypanosoma brucei glutathionylspermidine synthetase, putative 0.0055 0.027 0.0447
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0065 0.0341 0.1502
Entamoeba histolytica cysteine protease, putative 0.0157 0.0997 0.6162
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0061 0.0311 0.0534
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Entamoeba histolytica peptidase, C54 family 0.0068 0.0357 0.1856
Trypanosoma brucei calpain, putative 0.0395 0.2705 0.5653
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0107 0.0638 0.3457
Giardia lamblia Cathepsin L precursor 0.0033 0.011 0.0736
Echinococcus granulosus set and mynd domain containing protein 0.0024 0.0043 0.0003
Brugia malayi hypothetical protein 0.0057 0.028 0.1491
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0083 0.047 0.091
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0513 0.3547 0.7462
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0214 0.141 0.2911
Schistosoma mansoni hypothetical protein 0.0037 0.0141 0.0102
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0067 0.0354 0.0664
Brugia malayi Cathepsin L-like cysteine proteinase 0.0107 0.0638 0.3652
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0057 0.028 0.193
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0227 0.1502 0.147
Onchocerca volvulus 0.0057 0.028 0.2556
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0029 0.008 0.0434
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0068 0.0357 0.1936
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0192 0.1253 0.2577
Echinococcus granulosus jun protein 0.0028 0.0077 0.0172
Trypanosoma cruzi ubiquitin hydrolase, putative 0.011 0.0659 0.1312
Loa Loa (eye worm) hypothetical protein 0.0037 0.0141 0.0604
Brugia malayi CG8232-PA 0.0049 0.0223 0.1152
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.004 0.0161 0.0773
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0041 0.0168 0.077
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.011 0.0072
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Echinococcus multilocularis cysteine protease atg4b 0.0068 0.0357 0.0411
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0033 0.0106 0.0444
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Trypanosoma brucei pyroglutamyl-peptidase I, putative 0.0354 0.2411 0.5024
Toxoplasma gondii hypothetical protein 0.018 0.1163 0.908
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase BAP1 0.0051 0.0236 0.0974
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0084 0.0475 0.0438
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0283 0.1904 0.394
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0157 0.0997 0.5407
Echinococcus granulosus geminin 0.0301 0.2032 1
Leishmania major calpain protease-like protein 0.0206 0.135 0.2724
Leishmania major trypanothione synthetase-like protein 0.0055 0.027 0.0406
Giardia lamblia Cathepsin L-like protease 0.0033 0.011 0.0736
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0103 0.0609 0.0572
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0037 0.0141 0.0492
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0283 0.1904 0.3964
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0084 0.0475 0.2576
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0033 0.011 0.0419
Entamoeba histolytica cysteine protease, putative 0.0033 0.011 0.0195
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0257 0.1716 0.3564
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0061 0.0311 0.1638
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.001
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0084 0.0475 0.0846
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0033 0.0106 0.0068
Plasmodium vivax vivapain-3 0.0083 0.047 0.2722
Onchocerca volvulus Cathepsin L homolog 0.0033 0.011 0.0799
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0041 0.0168 0.1027
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.011 0.0597
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0057 0.028 0.0242
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0041 0.0168 0.013
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.011 0.0469
Trypanosoma brucei Calpain-like protein 2 0.0504 0.3486 0.7323
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0065 0.0338 0.1832
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0192 0.1253 0.2577
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0192 0.1253 0.2547
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0443 0.3045 0.6394
Trypanosoma cruzi kinesin, putative 0.0047 0.0213 0.0362
Trypanosoma cruzi cysteine peptidase, putative 0.0157 0.0997 0.2033
Trypanosoma cruzi ubiquitin hydrolase, putative 0.013 0.0802 0.1618
Schistosoma mansoni hypothetical protein 0.0301 0.2032 0.2001
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0033 0.011 0.0597
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0227 0.1502 0.7338
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Echinococcus granulosus PAB dependent polyA specific ribonuclease 0.0025 0.0054 0.0055
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0335 0.2275 0.471
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0033 0.011 0.0419
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0049 0.0224 0.1215
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0037 0.0141 0.0604
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0679 0.4738 1
Trypanosoma cruzi cysteine protease, putative 0.0083 0.047 0.091
Plasmodium falciparum serine repeat antigen 8 0.0033 0.011 0.0559
Brugia malayi Pepsin A precursor 0.0057 0.028 0.1491
Echinococcus multilocularis calpain A 0.0227 0.1502 0.191
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0033 0.011 0.0597
Schistosoma mansoni calpain C (C02 family) 0.0227 0.1502 0.147
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0074 0.0401 0.0364
Loa Loa (eye worm) hypothetical protein 0.0033 0.011 0.0419
Trypanosoma cruzi hypothetical protein, conserved 0.0275 0.1844 0.3837
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0192 0.1253 0.2547
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0141 0.0653
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0083 0.0465 0.0428
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0299 0.2016 0.4203
Toxoplasma gondii cathepsin B 0.0084 0.0475 0.3514
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0041 0.0168 0.013
Brugia malayi Papain family cysteine protease containing protein 0.0083 0.047 0.2639
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.047 0.0873
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0492 0.3402 0.7154
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.005 0.0233 0.1263
Loa Loa (eye worm) hypothetical protein 0.018 0.1163 0.6804
Plasmodium falciparum plasmepsin V 0.0057 0.028 0.193
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0041 0.0168 0.063
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0172
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0157 0.0997 0.5407
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0221 0.1455 0.2979
Schistosoma mansoni ubiquitinyl hydrolase-BAP1 (C12 family) 0.0051 0.0236 0.0199
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0161 0.1027 0.2064
Trypanosoma cruzi cysteine peptidase, putative 0.0273 0.1831 0.3809
Trypanosoma cruzi major cysteine proteinase, putative 0.0149 0.0944 0.1919
Brugia malayi Cathepsin L-like precursor 0.0157 0.0997 0.5823
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Schistosoma mansoni hypothetical protein 0.018 0.1163 0.1128
Leishmania major cathepsin L-like protease 0.0157 0.0997 0.1967
Plasmodium vivax ubiquitin C-terminal hydrolase, family 1, putative 0.0093 0.0538 0.3154
Trichomonas vaginalis ubiquitin specific protease, putative 0.0053 0.0255 0.138
Leishmania major cathepsin L-like protease 0.0273 0.1831 0.3758
Leishmania major hypothetical protein, conserved 0.0221 0.1455 0.295
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0033 0.0106 0.0575
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0065 0.0338 0.0386
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0273 0.1831 0.3784
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0033 0.011 0.0597
Brugia malayi Ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0103 0.0609 0.3478
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0067 0.0354 0.0586
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0037 0.0141 0.0492
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0329 0.2232 0.4663
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Plasmodium vivax vivapain-2 0.0157 0.0997 0.6072
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0329 0.2232 0.4619
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0037 0.0141 0.0632
Plasmodium falciparum cysteine protease ATG4, putative 0.0038 0.0145 0.0837
Echinococcus multilocularis expressed protein 0.0037 0.0141 0.0127
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0087 0.0494 0.0886
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0068 0.0357 0.067
Schistosoma mansoni calpain-7 (C02 family) 0.0291 0.1957 0.1926
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0087 0.0494 0.2783
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0061 0.0314 0.0354
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0679 0.4738 1
Trypanosoma brucei SUMO1/Ulp2, putative 0.0148 0.0935 0.1867
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0074 0.0401 0.1801
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.005 0.0233 0.1262
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0519 0.3591 0.7556
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Trypanosoma brucei CHAP domain containing protein, putative 0.0055 0.027 0.0447
Loa Loa (eye worm) hypothetical protein 0.005 0.0233 0.1161
Toxoplasma gondii exonuclease 0.005 0.0231 0.1539
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0033 0.011 0.0597
Trypanosoma cruzi diphthine synthase, putative 0.0029 0.0081 0.0082
Plasmodium falciparum plasmepsin III 0.0057 0.028 0.193
Giardia lamblia GPI-anchor transamidase, putative 0.005 0.0233 0.3853
Loa Loa (eye worm) hypothetical protein 0.0037 0.0141 0.0604
Plasmodium vivax GPI-anchor transamidase, putative 0.005 0.0233 0.1218
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0054 0.0262 0.0467
Brugia malayi aspartic protease BmAsp-1, identical 0.0057 0.028 0.1491
Echinococcus granulosus cathepsin L 0.0083 0.047 0.2147
Plasmodium falciparum serine repeat antigen 7 0.0033 0.011 0.0559
Trichomonas vaginalis phosphofructokinase, putative 0.0054 0.0262 0.1422
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0257 0.1716 0.3564
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0029 0.008 0.0434
Leishmania major cathepsin L-like protease 0.0273 0.1831 0.3758
Trypanosoma brucei trypanothione synthetase 0.0055 0.027 0.0447
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0057 0.028 0.1446
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0073 0.0394 0.374
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0049 0.0224 0.1481
Brugia malayi cathepsin L-like cysteine proteinase 0.0033 0.011 0.0469
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0037 0.0141 0.0127
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma brucei hypothetical protein 0.0395 0.2705 0.5653
Toxoplasma gondii aspartyl protease ASP3 0.0057 0.028 0.193
Onchocerca volvulus 0.0107 0.0638 0.627
Trypanosoma brucei small myristoylated protein 1-1 0.0344 0.2337 0.4866
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.011 0.0597
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0093 0.0538 0.1055
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.011 0.0597
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0033 0.011 0.0438
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Entamoeba histolytica cysteine proteinase 2 0.0083 0.047 0.2614
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Plasmodium vivax vivapain-1 0.0083 0.047 0.2722
Brugia malayi 6-phosphofructokinase 0.0054 0.0262 0.1387
Giardia lamblia Cysteine protease 0.0033 0.011 0.0736
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0054 0.0262 0.1217
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0037 0.0141 0.0806
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0087 0.0494 0.0924
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0065 0.0338 0.1843
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0037 0.0141 0.0102
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0054 0.0262 0.0286
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0037 0.0141 0.0806
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0057 0.028 0.1516
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0054 0.0262 0.0429
Echinococcus multilocularis Ubiquitin thioesterase otubain protein 0.0071 0.038 0.044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0168 0.0911
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0084 0.0475 0.0921
Entamoeba histolytica protein kinase, putative 0.0047 0.0213 0.0884
Loa Loa (eye worm) hypothetical protein 0.0033 0.0106 0.0394
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0041 0.0168 0.063
Loa Loa (eye worm) hypothetical protein 0.004 0.0161 0.0724
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0063 0.0327 0.0605
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0033 0.011 0.0736
Loa Loa (eye worm) hypothetical protein 0.0057 0.028 0.1446
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0519 0.3591 0.7556
Loa Loa (eye worm) hypothetical protein 0.0028 0.0071 0.0183
Leishmania major kinesin, putative 0.0047 0.0213 0.0282
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.011 0.0072
Brugia malayi Peptidase family C54 containing protein 0.0068 0.0357 0.1959
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0087 0.0494 0.096
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase isozyme L3 0.0103 0.0609 0.4596
Giardia lamblia Cathepsin L-like protease 0.0033 0.011 0.0736
Entamoeba histolytica cysteine protease, putative 0.0083 0.047 0.2614
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0083 0.0465 0.09
Brugia malayi cathepsin Z-like cysteine proteinase 0.0033 0.011 0.0469
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0033 0.011 0.0559
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0074 0.0401 0.0726
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0026 0.0062 0.004
Entamoeba histolytica cysteine protease inhibitor 1 (EhICP1) 0.0193 0.1254 0.7884
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0299 0.2016 0.4203
Brugia malayi Calcitonin receptor-like protein seb-1 0.004 0.0161 0.0773
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.011 0.0597
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0103 0.0609 0.2846
Trypanosoma cruzi pyroglutamyl-peptidase I, putative 0.0354 0.2411 0.5044
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0443 0.3045 0.6394
Plasmodium vivax aspartyl proteinase, putative 0.0057 0.028 0.1514
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0537 0.3724 0.7823
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0037 0.0141 0.0806
Toxoplasma gondii aspartyl protease ASP1 0.0057 0.028 0.193
Loa Loa (eye worm) MH2 domain-containing protein 0.0108 0.0645 0.3664
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.1455 0.3007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0065 0.0338 0.18
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Brugia malayi Peptidase C13 family protein 0.0029 0.008 0.0287
Onchocerca volvulus 0.0033 0.011 0.0799
Echinococcus multilocularis cathepsin L cysteine protease 0.0157 0.0997 0.1249
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0033 0.0106 0.0318
Echinococcus multilocularis GPI anchor transamidase 0.005 0.0233 0.0248
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0061 0.0314 0.0354
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0074 0.0401 0.2174
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0054 0.0262 0.0389
Brugia malayi ubiquitin C-terminal hydrolase UCH-L5 0.0093 0.0538 0.305
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0157 0.0997 0.5801
Loa Loa (eye worm) peptidase C13 family protein 0.0029 0.008 0.0236
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0468 0.3227 0.6782
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.011 0.0659 0.0805
Loa Loa (eye worm) hypothetical protein 0.0107 0.0638 0.3619
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0299 0.2016 0.418
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0074 0.0401 0.2174
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0055 0.0268 0.1452
Entamoeba histolytica cysteine protease, putative 0.0083 0.047 0.2614
Brugia malayi cathepsin L-like precursor 0.0107 0.0638 0.3652
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0074 0.0401 0.0468
Schistosoma mansoni calpain (C02 family) 0.0227 0.1502 0.147
Leishmania major cathepsin L-like protease 0.0273 0.1831 0.3758
Giardia lamblia Cathepsin B precursor 0.0033 0.011 0.0736
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0214 0.141 0.2853
Entamoeba histolytica cysteine protease, putative 0.0083 0.047 0.2614
Plasmodium vivax unspecified product 0.005 0.0233 0.1215
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0103 0.0609 0.3301
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0175 0.1126 0.2277
Loa Loa (eye worm) hypothetical protein 0.0033 0.011 0.0419
Leishmania major hypothetical protein, conserved 0.0357 0.2432 0.5048
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0643 0.4484 0.9454
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0068 0.0357 0.1936
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.011 0.0659 0.3571
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Brugia malayi aspartic protease BmAsp-2, identical 0.0057 0.028 0.1491
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0065 0.0338 0.1484
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0544 0.3771 0.7924
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0037 0.0141 0.0762
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0061 0.0314 0.0276
Leishmania major small myristoylated protein-1 0.0344 0.2337 0.4844
Giardia lamblia Hypothetical protein 0.0033 0.011 0.0736
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.006 0.03 0.0549
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0175 0.1126 0.2245
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0037 0.0141 0.0762
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0057 0.028 0.1446
Onchocerca volvulus Cathepsin F homolog 0.0157 0.0997 1
Trichomonas vaginalis phosphofructokinase, putative 0.0054 0.0262 0.1422
Loa Loa (eye worm) hypothetical protein 0.0037 0.0141 0.0604
Trypanosoma cruzi hypothetical protein, conserved 0.0055 0.027 0.0485
Echinococcus multilocularis geminin 0.0301 0.2032 0.2603
Leishmania major cathepsin L-like protease 0.0157 0.0997 0.1967
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Echinococcus granulosus Ubiquitin thioesterase otubain protein 0.0071 0.038 0.1693
Schistosoma mansoni cathepsin F (C01 family) 0.0107 0.0638 0.0601
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0065 0.0338 0.1884
Toxoplasma gondii aspartyl protease 0.0057 0.028 0.193
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Entamoeba histolytica phosphofructokinase, putative 0.0054 0.0262 0.1218
Leishmania major cathepsin L-like protease 0.0157 0.0997 0.1967
Entamoeba histolytica peptidase, C54 family 0.0038 0.0145 0.0426
Echinococcus multilocularis calpain 0.0227 0.1502 0.191
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0083 0.0465 0.2572
Leishmania major receptor-type adenylate cyclase a-like protein 0.0221 0.1455 0.295
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.047 0.2547
Plasmodium vivax hypothetical protein, conserved 0.0054 0.0262 0.1403
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase UCHL3 0.0103 0.0609 0.4596
Trypanosoma cruzi diphthine synthase, putative 0.0029 0.0081 0.0082
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0468 0.3227 0.6782
Schistosoma mansoni hypothetical protein 0.0027 0.0069 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0273 0.1831 0.3784
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0148 0.0935 0.19
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0074 0.0401 0.2174
Trypanosoma cruzi ubiquitin hydrolase, putative 0.005 0.0231 0.0401
Plasmodium falciparum cysteine proteinase falcipain 3 0.0157 0.0997 0.7742
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0061 0.0311 0.1681
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0074 0.0401 0.2174
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.006 0.03 0.0471
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0492 0.3402 0.7154
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0093 0.0538 0.3072
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0033 0.011 0.0419
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Entamoeba histolytica cysteine proteinase, putative 0.0083 0.047 0.2614
Trypanosoma cruzi trypanothione synthetase 0.0055 0.027 0.0485
Brugia malayi 6-phosphofructokinase 0.0054 0.0262 0.1387
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0157 0.0997 0.5407
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.011 0.0597
Loa Loa (eye worm) hypothetical protein 0.006 0.03 0.1572
Loa Loa (eye worm) hypothetical protein 0.0037 0.0141 0.0604
Toxoplasma gondii ubiquitin thioesterase otubain-like family protein 0.0071 0.038 0.274
Loa Loa (eye worm) hypothetical protein 0.0057 0.028 0.1446
Brugia malayi Cathepsin L-like precursor 0.0107 0.0638 0.3652
Entamoeba histolytica phosphofructokinase, putative 0.0054 0.0262 0.1218
Entamoeba histolytica cysteine proteinase, putative 0.0107 0.0638 0.3743
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0401 0.2745 0.5754
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0054 0.0262 1
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0037 0.0141 0.0102
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0065 0.0338 0.1832
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0161 0.1027 0.2031
Loa Loa (eye worm) phosphofructokinase 0.0054 0.0262 0.1342
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0033 0.011 0.0195
Giardia lamblia Cathepsin B precursor 0.0084 0.0475 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0033 0.011 0.0195
Leishmania major PFPI/DJ-1-like protein, putative 0.0372 0.2537 0.5274
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0679 0.4738 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0033 0.011 0.0072
Trypanosoma cruzi trypanothione synthetase, putative 0.0055 0.027 0.0485
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.047 0.0873
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Schistosoma mansoni autophagin-1 (C54 family) 0.0068 0.0357 0.032
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.0093 0.0538 0.0501
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0074 0.0401 0.0763
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0519 0.3591 0.7536
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.013 0.0802 0.1584
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Schistosoma mansoni Mername-AA248 (C02 family) 0.0227 0.1502 0.147
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0037 0.0141 0.0492
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.006 0.03 0.0511
Plasmodium vivax aspartyl protease, putative 0.0057 0.028 0.1514
Loa Loa (eye worm) aspartyl protease 6 0.0057 0.028 0.1446
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0168 0.0818
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.1455 0.2979
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0065 0.0341 0.175
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0074 0.0401 0.2174
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0065 0.0341 0.0636
Loa Loa (eye worm) calpain 0.0253 0.169 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0054 0.0262 0.0429
Trichomonas vaginalis phosphofructokinase, putative 0.0054 0.0262 0.1422
Schistosoma mansoni cathepsin B (C01 family) 0.0033 0.011 0.0072
Trypanosoma brucei Calpain-like protein 1.2 0.0519 0.3591 0.7546
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0057 0.028 0.1191
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.006 0.03 0.0263
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0093 0.0538 0.0647
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0049 0.0224 0.1215
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0157 0.0997 0.5407
Entamoeba histolytica cysteine protease, putative 0.0083 0.047 0.2614
Toxoplasma gondii ubiquitin-specific protease USP4 0.0037 0.0141 0.0806
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0074 0.0401 0.2174
Loa Loa (eye worm) papain family cysteine protease containing protein 0.005 0.0233 0.1161
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0033 0.011 0.0438
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0537 0.3724 0.7841
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0074 0.0401 0.2174
Loa Loa (eye worm) ctsf protein 0.0157 0.0997 0.5801
Entamoeba histolytica cysteine protease, putative 0.0083 0.047 0.2614
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.011 0.0597
Entamoeba histolytica peptidase, C54 family 0.0038 0.0145 0.0426
Plasmodium vivax unspecified product 0.0083 0.047 0.2722
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0054 0.0262 0.1421
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0157 0.0997 0.5407
Loa Loa (eye worm) hypothetical protein 0.0073 0.0394 0.2139
Trypanosoma cruzi trypanothione synthetase, putative 0.0055 0.027 0.0485
Schistosoma mansoni peptidase 0.0037 0.0141 0.0102
Leishmania major pyroglutamyl-peptidase I (C15 family) 0.0354 0.2411 0.5003
Loa Loa (eye worm) calpain family protein 1 0.018 0.1163 0.6804
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0273 0.1831 0.3784
Brugia malayi latrophilin 2 splice variant baaae 0.0027 0.0069 0.0224
Trypanosoma brucei cysteine peptidase, putative 0.0468 0.3227 0.6769
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0257 0.1716 0.3564
Echinococcus granulosus cathepsin L cysteine proteinase 0.0157 0.0997 0.4799
Entamoeba histolytica cysteine proteinase, putative 0.0157 0.0997 0.6162
Toxoplasma gondii hypothetical protein 0.0065 0.0336 0.2388
Plasmodium vivax aspartyl protease, putative 0.0057 0.028 0.1514
Brugia malayi calpain 7 0.0253 0.169 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.005 0.0231 0.0322
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0492 0.3402 0.7131
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.011 0.0659 0.0622
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0033 0.011 0.0736
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0083 0.047 0.0433
Entamoeba histolytica cysteine protease, putative 0.0083 0.047 0.2614
Echinococcus granulosus calpain 7 C02 family 0.0253 0.169 0.8278
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0103 0.0609 0.1206
Leishmania major META domain containing protein 0.0221 0.1455 0.295
Trypanosoma brucei small myristoylated protein 1-2 0.0344 0.2337 0.4866
Echinococcus granulosus 6 phosphofructokinase 0.0054 0.0262 0.1104
Entamoeba histolytica cysteine protease, putative 0.0033 0.011 0.0195
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0087 0.0494 0.096
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.005 0.0233 0.0195
Loa Loa (eye worm) hypothetical protein 0.0084 0.0475 0.2633
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.018 0.1163 0.6304
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0033 0.011 0.0597
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0061 0.0311 0.0534
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0214 0.141 0.2853
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0093 0.0538 0.0647
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0037 0.0141 0.0127
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0157 0.0997 0.1249
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0065 0.0341 0.039
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0033 0.011 0.0438
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase BAP1 0.0051 0.0236 0.0253
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Schistosoma mansoni calpain-2 (C02 family) 0.018 0.1163 0.1128
Trypanosoma cruzi cysteine peptidase, putative 0.0083 0.047 0.091
Plasmodium falciparum serine repeat antigen 2 0.0033 0.011 0.0559
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0061 0.0314 0.1652
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Entamoeba histolytica cysteine proteinase, putative 0.0083 0.047 0.2614
Loa Loa (eye worm) hypothetical protein 0.0037 0.0141 0.0604
Echinococcus multilocularis 6 phosphofructokinase 0.0054 0.0262 0.0287
Brugia malayi Cathepsin L-like precursor 0.0157 0.0997 0.5823
Loa Loa (eye worm) hypothetical protein 0.005 0.0233 0.1161
Loa Loa (eye worm) hypothetical protein 0.0103 0.0609 0.3444
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0065 0.0341 0.0304
Onchocerca volvulus 0.0157 0.0997 1
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0041 0.0168 0.0806
Plasmodium falciparum plasmepsin I 0.0057 0.028 0.193
Entamoeba histolytica peptidase, C54 family 0.0161 0.1027 0.6361
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0107 0.0638 0.3457
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0061 0.0314 0.1696
Echinococcus multilocularis cathepsin b 0.0084 0.0475 0.0565
Onchocerca volvulus 0.0057 0.028 0.2556
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0037 0.0141 0.0492
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0083 0.0465 0.0552
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0168 0.0911
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0068 0.0357 0.032
Plasmodium falciparum cysteine proteinase falcipain 1 0.0083 0.047 0.3471
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0382 0.2614 0.5459
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Loa Loa (eye worm) hypothetical protein 0.0107 0.0638 0.3619
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Leishmania major hypothetical protein, conserved 0.0275 0.1844 0.3786
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.011 0.0469
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.018 0.1163 0.6304
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0175 0.1126 0.2308
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.011 0.0597
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0033 0.011 0.0438
Brugia malayi Cathepsin L-like precursor 0.0157 0.0997 0.5823
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Plasmodium vivax plasmepsin V, putative 0.0057 0.028 0.1514
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0148 0.0935 0.1833
Echinococcus granulosus calpain 0.0227 0.1502 0.7338
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.011 0.0659 0.3884
Schistosoma mansoni calpain-7 (C02 family) 0.0291 0.1957 0.1926
Loa Loa (eye worm) hypothetical protein 0.005 0.0233 0.1164
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.005 0.0233 0.1207
Brugia malayi calpain family protein 1 0.0227 0.1502 0.8871
Trypanosoma cruzi kinesin, putative 0.0047 0.0213 0.0362
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0093 0.0538 0.0981
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Leishmania major small myristoylated protein 4, putative 0.0513 0.3547 0.7441
Schistosoma mansoni cathepsin F (C01 family) 0.0157 0.0997 0.0962
Echinococcus granulosus calpain A 0.0227 0.1502 0.7338
Leishmania major cysteine peptidase A (CPA) 0.0157 0.0997 0.1967
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0192 0.1253 0.2516
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0157 0.0997 0.5407
Entamoeba histolytica cysteine protease, putative 0.0083 0.047 0.2614
Plasmodium vivax serine-repeat antigen (SERA) 0.0033 0.011 0.0438
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0057 0.028 0.0242
Onchocerca volvulus Legumain homolog 0.0029 0.008 0.0487
Leishmania major small myristoylated protein-2 0.0585 0.4063 0.8551
Onchocerca volvulus 0.0157 0.0997 1
Schistosoma mansoni cathepsin D (A01 family) 0.0057 0.028 0.0242
Echinococcus granulosus cathepsin L 0.0033 0.011 0.0339
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0462 0.3187 0.6684
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0037 0.0141 0.0102
Giardia lamblia Cysteine protease 0.0033 0.011 0.0736
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Schistosoma mansoni hemoglobinase (C13 family) 0.0029 0.008 0.0042
Plasmodium falciparum serine repeat antigen 3 0.0033 0.011 0.0559
Trypanosoma cruzi ubiquitin hydrolase, putative 0.023 0.1524 0.3154
Plasmodium falciparum diphthine methyl ester synthase, putative 0.0029 0.0081 0.0324
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0067 0.0354 0.1921
Trypanosoma brucei amidase, putative 0.0055 0.027 0.0447
Brugia malayi diphthine synthase 0.0029 0.0081 0.0294
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0037 0.0141 0.0102
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0037 0.0141 0.0604
Giardia lamblia Cathepsin L precursor 0.0033 0.011 0.0736
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.005 0.0233 0.0405
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0054 0.0262 0.1386
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0054 0.0262 0.1789
Loa Loa (eye worm) hypothetical protein 0.0037 0.0141 0.0604
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0061 0.0314 0.1361
Trypanosoma brucei antigen, putative 0.0227 0.1502 0.3081
Onchocerca volvulus 0.0157 0.0997 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0065 0.0341 0.1851
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0336 0.1822
Brugia malayi hypothetical protein 0.0037 0.0141 0.0653
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0068 0.0357 0.1936
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0443 0.3045 0.6394
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0273 0.1831 0.3784
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0257 0.1716 0.3564
Giardia lamblia Hypothetical protein 0.0041 0.0168 0.2203
Entamoeba histolytica cysteine protease, putative 0.0033 0.011 0.0195
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0141 0.0653
Echinococcus multilocularis cathepsin L cysteine protease 0.0157 0.0997 0.1249
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0037 0.0141 0.0127
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0054 0.0262 0.0467
Trypanosoma cruzi hypothetical protein, conserved 0.0275 0.1844 0.3837
Trypanosoma cruzi ubiquitin hydrolase, putative 0.013 0.0802 0.1618
Plasmodium vivax ubiquitin specific protease, putative 0.0037 0.0141 0.0632
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trichomonas vaginalis calpain, putative 0.018 0.1163 0.6304
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0103 0.0609 0.074
Echinococcus granulosus cathepsin l1 0.0107 0.0638 0.2991
Onchocerca volvulus 0.0157 0.0997 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0037 0.0141 0.0492
Plasmodium vivax plasmepsin IV, putative 0.0057 0.028 0.1514
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.006 0.03 0.2098
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0029 0.008 0.0434
Plasmodium vivax calpain, putative 0.0243 0.1616 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0074 0.0401 0.2174
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0214 0.141 0.2911
Loa Loa (eye worm) hypothetical protein 0.0227 0.1502 0.8865
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0033 0.011 0.0597
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0382 0.2614 0.5477
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.011 0.0072
Loa Loa (eye worm) hypothetical protein 0.0029 0.0083 0.0257
Trypanosoma brucei cysteine peptidase, Clan CA, family C51, putative 0.0257 0.1716 0.3538
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0033 0.011 0.0736
Loa Loa (eye worm) hypothetical protein 0.0029 0.0081 0.0243
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0067 0.0354 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0157 0.0997 0.5407
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0065 0.0341 0.1851
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0054 0.0262 0.1789
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0028 0.0077 0.0172
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0055 0.0268 0.1452
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0051 0.0236 0.0374
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0157 0.0997 0.5407
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0033 0.011 0.0438
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0273 0.1831 0.3784
Plasmodium vivax unspecified product 0.0033 0.011 0.0438
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0395 0.2705 0.5635
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0065 0.0341 0.0599
Brugia malayi Cathepsin L-like precursor 0.0107 0.0638 0.3652
Brugia malayi Papain family cysteine protease containing protein 0.0157 0.0997 0.5823
Entamoeba histolytica cysteine proteinase 1, putative 0.0083 0.047 0.2614
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0221 0.1455 0.2979
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0215 0.1415 0.2895
Plasmodium falciparum plasmepsin VII 0.0057 0.028 0.193
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0215 0.1415 0.2895
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0468 0.3227 0.6769
Entamoeba histolytica cysteine protease, putative 0.0033 0.011 0.0195
Plasmodium falciparum ubiquitin specific protease, putative 0.0037 0.0141 0.0806
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0061 0.0314 0.1361
Brugia malayi fibroinase precursor 0.0033 0.011 0.0469
Schistosoma mansoni diphthine synthase 0.0029 0.0081 0.0043
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0335 0.2275 0.4754
Schistosoma mansoni hemoglobinase (C13 family) 0.0029 0.008 0.0042
Schistosoma mansoni cathepsin D (A01 family) 0.0057 0.028 0.0242
Plasmodium falciparum deubiquinating/deneddylating enzyme 0.0093 0.0538 0.4022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0157 0.0997 0.5407
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Onchocerca volvulus Cathepsin L homolog 0.0157 0.0997 1
Brugia malayi ubiquitin specific protease 14 0.006 0.03 0.1616
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0037 0.0141 0.0492
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0033 0.011 0.0736
Echinococcus granulosus calpain A 0.0227 0.1502 0.7338
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0029 0.008 0.0434
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Entamoeba histolytica cysteine protease, putative 0.0033 0.011 0.0195
Schistosoma mansoni hypothetical protein 0.0301 0.2032 0.2001
Entamoeba histolytica hypothetical protein 0.0051 0.0236 0.1044
Leishmania major cathepsin L-like protease 0.0157 0.0997 0.1967
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0037 0.0141 0.0806
Trypanosoma cruzi Cysteine peptidase, Clan CF, family C15 0.0354 0.2411 0.5044
Loa Loa (eye worm) hypothetical protein 0.0047 0.0213 0.104
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0443 0.3045 0.6364
Brugia malayi Cathepsin L-like precursor 0.0157 0.0997 0.5823
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0084 0.0475 0.0438
Loa Loa (eye worm) fibroinase 0.0157 0.0997 0.5801
Leishmania major small myristoylated protein-3, putative 0.0299 0.2016 0.4155
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.006 0.03 0.0549
Trichomonas vaginalis calpain, putative 0.018 0.1163 0.6304
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.005 0.0233 0.1263
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0192 0.1253 0.2577
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.006 0.03 0.2098
Loa Loa (eye worm) hypothetical protein 0.0107 0.0638 0.3619
Onchocerca volvulus 0.0037 0.0141 0.1116
Onchocerca volvulus 0.0157 0.0997 1
Onchocerca volvulus 0.0157 0.0997 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Giardia lamblia Cathepsin L precursor 0.0033 0.011 0.0736
Giardia lamblia Cathepsin L precursor 0.0033 0.011 0.0736
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0341 0.1851
Leishmania major cathepsin L-like protease 0.0157 0.0997 0.1967
Brugia malayi N-terminal motif family protein 0.0073 0.0394 0.218
Leishmania major hypothetical protein, conserved 0.0055 0.027 0.0406
Trypanosoma cruzi ubiquitin hydrolase, putative 0.011 0.0659 0.1312
Leishmania major trypanothione synthetase, putative 0.0055 0.027 0.0406
Giardia lamblia Encystation-specific protease 0.0033 0.011 0.0736
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Entamoeba histolytica cysteine protease, putative 0.0083 0.047 0.2614
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0033 0.0106 0.0082
Giardia lamblia Cysteine protease 0.0033 0.011 0.0736
Trypanosoma cruzi cysteine peptidase, putative 0.0273 0.1831 0.3809
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma cruzi major cysteine proteinase, putative 0.0033 0.011 0.0144
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.006 0.03 0.0336
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0037 0.0141 0.0806
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0037 0.0141 0.0492
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0065 0.0341 0.1865
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0192 0.1253 0.2516
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0061 0.0311 0.0572
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.0093 0.0538 0.0501
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0168 0.0584
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0068 0.0357 0.0593
Echinococcus multilocularis Peptidase C54 0.0068 0.0357 0.0411
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0221 0.1455 0.3007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.006 0.03 0.1628
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0037 0.0141 0.0127
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.006 0.03 0.556
Plasmodium vivax vivapain-2 0.0157 0.0997 0.6072
Trypanosoma brucei diphthine synthase, putative 0.0029 0.0081 0.0042
Entamoeba histolytica cysteine protease inhibitor 2 (EhICP2) 0.0193 0.1254 0.7884
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0157 0.0997 0.5407
Schistosoma mansoni ubiquitin specific protease 52 / poly(A) ribonuclease subunit pan2 0.0025 0.0054 0.0015
Trypanosoma brucei Calpain-like protein CALP1.3 0.0401 0.2745 0.5737
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0103 0.0609 0.0572
Trypanosoma brucei calpain-like protein, putative 0.0243 0.1616 0.3324
Loa Loa (eye worm) hypothetical protein 0.006 0.03 0.1572
Plasmodium falciparum plasmepsin II 0.0057 0.028 0.193
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0544 0.3771 0.7924
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.011 0.0469
Entamoeba histolytica cysteine protease, putative 0.0083 0.047 0.2614
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.011 0.0597
Echinococcus granulosus cathepsin l cysteine peptidase 0.0157 0.0997 0.4799
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Plasmodium falciparum plasmepsin X 0.0057 0.028 0.193
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0273 0.1831 0.3784
Trypanosoma cruzi cysteine peptidase, putative 0.0273 0.1831 0.3809
Plasmodium falciparum plasmepsin IX 0.0057 0.028 0.193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0157 0.0997 0.5407
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.011 0.0659 0.124
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0141 0.0653
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0054 0.0262 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0157 0.0997 0.1249
Brugia malayi phosphofructokinase 0.0054 0.0262 0.1387
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0157 0.0997 0.5407
Entamoeba histolytica calpain family cysteine protease, putative 0.0237 0.1568 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.0084 0.0475 0.0885
Trypanosoma brucei inhibitor of cysteine peptidase 0.0193 0.1254 0.2549
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.109 0.7685 1
Trypanosoma brucei conserved protein 0.0177 0.1142 0.231
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0067 0.0351 0.1969
Trypanosoma cruzi cysteine peptidase, putative 0.005 0.0233 0.0404
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0175 0.1126 0.2308
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Onchocerca volvulus 0.0157 0.0997 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0065 0.0338 0.1832
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.011 0.0597
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0504 0.3486 0.7311
Mycobacterium ulcerans hypothetical protein 0.0082 0.0457 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0074 0.0401 0.0763
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.1455 0.3007
Loa Loa (eye worm) hypothetical protein 0.0068 0.0357 0.1917
Plasmodium vivax aspartyl protease, putative 0.0057 0.028 0.1514
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0468 0.3227 0.6755
Entamoeba histolytica cysteine proteinase, putative 0.0083 0.047 0.2614
Loa Loa (eye worm) hypothetical protein 0.0037 0.0141 0.0604
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0033 0.011 0.0438
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0141 0.0762
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0083 0.047 0.0433
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0243 0.1616 0.3351
Plasmodium vivax aspartyl proteinase, putative 0.0057 0.028 0.1514
Trypanosoma cruzi small myristoylated protein 1-1 0.0344 0.2337 0.4887
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0093 0.0538 0.2489
Echinococcus granulosus cathepsin b 0.0084 0.0475 0.2174
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.018 0.1163 0.2355
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0061 0.0311 0.0273
Trypanosoma cruzi conserved protein 0.0357 0.2432 0.5088
Trypanosoma cruzi glutathionylspermidine synthase, putative 0.0055 0.027 0.0485
Trypanosoma brucei cysteine peptidase, Clan CA, family C51, putative 0.0257 0.1716 0.3538
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0037 0.0141 0.0632
Loa Loa (eye worm) hypothetical protein 0.0033 0.011 0.0419
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Plasmodium falciparum serine repeat antigen 4 0.0033 0.011 0.0559
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.1455 0.3007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0157 0.0997 0.5407
Leishmania major hypothetical protein, conserved 0.0221 0.1455 0.295
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.1455 0.2979
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0074 0.0401 0.2174
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0074 0.0401 0.0763
Giardia lamblia Cathepsin B precursor 0.0033 0.011 0.0736
Loa Loa (eye worm) calpain family protein 1 0.0227 0.1502 0.8865
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0643 0.4484 0.9454
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0168 0.0818
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Entamoeba histolytica cysteine protease, putative 0.0083 0.047 0.2614
Loa Loa (eye worm) pigment dispersing factor receptor c 0.004 0.0161 0.0724
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0335 0.2275 0.471
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0054 0.0262 0.1103
Echinococcus multilocularis calpain 5 0.0227 0.1502 0.191
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0215 0.1415 0.2895
Leishmania major hypothetical protein, unknown function 0.0544 0.3771 0.7924
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0054 0.0262 0.1103
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0401 0.2745 0.5754
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0215 0.1415 0.2895
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0335 0.2275 0.4732
Entamoeba histolytica calpain large subunit domain III containing protein 0.0047 0.0213 0.0884
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0679 0.4738 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma brucei hypothetical protein, conserved 0.0275 0.1844 0.3812
Trypanosoma cruzi cysteine proteinase, putative 0.0083 0.047 0.091
Echinococcus multilocularis hypothetical protein 0.0227 0.1502 0.191
Echinococcus granulosus ubiquitin specific protease 41 0.0065 0.0341 0.1502
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0273 0.1831 0.3784
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0192 0.1253 0.2516
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0061 0.0311 0.035
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0192 0.1253 0.2577
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Loa Loa (eye worm) hypothetical protein 0.0065 0.0341 0.1822
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0141 0.04
Loa Loa (eye worm) 6-phosphofructokinase 0.0054 0.0262 0.1342
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0299 0.2016 0.418
Entamoeba histolytica cysteine proteinase, putative 0.0157 0.0997 0.6162
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0083 0.0465 0.0825
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0083 0.047 0.0433
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0157 0.0997 0.5407
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0331 0.2244 0.4644
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0257 0.1716 0.3564
Giardia lamblia Cathepsin B precursor 0.0033 0.011 0.0736
Leishmania major hypothetical protein, conserved 0.0221 0.1455 0.295
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0038 0.0145 0.0837
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0065 0.0341 0.0304
Brugia malayi cathepsin F-like cysteine proteinase 0.005 0.0233 0.1207
Loa Loa (eye worm) hypothetical protein 0.0049 0.0223 0.1105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Echinococcus granulosus GPI anchor transamidase 0.005 0.0233 0.0956
Brugia malayi cathepsin B-like cysteine proteinase 0.0084 0.0475 0.2672
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0067 0.0354 0.0626
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0643 0.4484 0.9454
Brugia malayi hypothetical protein 0.0057 0.028 0.1491
Leishmania major inhibitor of cysteine peptidase 0.0193 0.1254 0.2517
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0033 0.011 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0157 0.0997 0.5407
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0057 0.028 0.0242
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0215 0.1415 0.2923
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0157 0.0997 0.5407
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.005 0.0233 0.0405
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0067 0.0354 0.2535
Leishmania major otubain, putative,otubain cysteine peptidase, Clan CA, family C65, putative 0.0071 0.038 0.0641
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Loa Loa (eye worm) transcription factor SMAD2 0.0108 0.0645 0.3664
Schistosoma mansoni 6-phosphofructokinase 0.0054 0.0262 0.0225
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0087 0.0494 0.2745
Toxoplasma gondii preprocathepsin c precursor, putative 0.0033 0.011 0.0559
Trichomonas vaginalis hypothetical protein 0.018 0.1163 0.6304
Loa Loa (eye worm) cysteine protease 0.0157 0.0997 0.5801
Schistosoma mansoni otubain-1 (C65 family) 0.0071 0.038 0.0342
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Leishmania major D-alanyl-glycyl endopeptidase-like protein,cysteine peptidase, Clan CA, family C51, putative 0.0257 0.1716 0.3511
Leishmania major trypanothione synthetase, putative 0.0055 0.027 0.0406
Loa Loa (eye worm) hypothetical protein 0.0033 0.011 0.0419
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0041 0.0168 0.1027
Plasmodium falciparum calpain 0.0196 0.1276 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma cruzi unspecified product 0.0344 0.2337 0.4887
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0157 0.0997 0.5407
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0084 0.0475 0.0438
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0061 0.0314 0.0276
Loa Loa (eye worm) hypothetical protein 0.0071 0.038 0.2053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.011 0.0597
Schistosoma mansoni 6-phosphofructokinase 0.0054 0.0262 0.0225
Echinococcus multilocularis cathepsin b 0.0084 0.0475 0.0565
Trypanosoma brucei Calpain-like protein 1.1 0.0679 0.4738 1
Entamoeba histolytica peptidase, C54 family 0.0038 0.0145 0.0426
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0065 0.0341 0.6606
Plasmodium vivax diphthine synthase, putative 0.0029 0.0081 0.0254
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0103 0.0609 0.117
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0331 0.2244 0.4688
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0033 0.011 0.0438
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0462 0.3187 0.667
Trichomonas vaginalis conserved hypothetical protein 0.018 0.1163 0.6304
Brugia malayi cathepsin Z-like cysteine proteinase 0.0033 0.011 0.0469
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0033 0.011 0.0438
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.005 0.0233 0.1262
Echinococcus multilocularis cathepsin L 0.0083 0.047 0.0558
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0029 0.008 0.0434
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0037 0.0141 0.0806
Trypanosoma cruzi cruzipain precursor, putative 0.0273 0.1831 0.3809
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0065 0.0338 0.2402
Schistosoma mansoni cathepsin s 0.005 0.0233 0.0195
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0137 0.0852 0.1724
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0033 0.0106 0.0575
Brugia malayi cathepsin L precursor 0.0033 0.011 0.0469
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0074 0.0401 0.2174
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0033 0.011 0.0559
Trypanosoma cruzi small myristoylated protein 1-2 0.0344 0.2337 0.4887
Trypanosoma brucei otubain cysteine peptidase, Clan CA, family C65, putative 0.0071 0.038 0.068
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.013 0.0802 0.485
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0157 0.0997 0.5407
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0054 0.0262 0.0286
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0068 0.0357 0.1936
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0057 0.028 0.0242
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0141 0.0653
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0065 0.0338 0.6514
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0192 0.1253 0.2547
Trypanosoma cruzi cysteine peptidase inhibitor, putative 0.0193 0.1254 0.2579
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0537 0.3724 0.7841
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0037 0.0141 0.0102
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0083 0.0465 0.2611
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0054 0.0262 0.5
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Trichomonas vaginalis ubiquitin specific protease, putative 0.0037 0.0141 0.0762
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0227 0.1502 0.147
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0083 0.0465 0.2123
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0443 0.3045 0.6379
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0087 0.0494 0.2267
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0141 0.0762
Entamoeba histolytica phosphofructokinase, putative 0.0054 0.0262 0.1218
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.1455 0.2979
Plasmodium falciparum plasmepsin VIII, putative 0.0057 0.028 0.193
Loa Loa (eye worm) cathepsin B 0.0084 0.0475 0.2633
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0273 0.1831 0.3784
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0141 0.04
Plasmodium falciparum serine repeat antigen 1 0.0033 0.011 0.0559
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0057 0.028 0.0242
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0074 0.0401 0.2174
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0041 0.0168 0.0163
Plasmodium falciparum serine repeat antigen 5 0.0033 0.011 0.0559
Trypanosoma brucei calpain-like protein, putative 0.0227 0.1502 0.3081
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0037 0.0141 0.0102
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0168 0.0911
Trypanosoma brucei calpain, putative 0.018 0.1163 0.2355
Loa Loa (eye worm) 6-phosphofructokinase 0.0054 0.0262 0.1342
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0157 0.0997 0.5801
Brugia malayi MH2 domain containing protein 0.0108 0.0645 0.3697
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0141 0.0653
Plasmodium falciparum plasmepsin IV 0.0057 0.028 0.193
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0087 0.0494 0.0589
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0161 0.1027 0.2096
Brugia malayi Eukaryotic aspartyl protease family protein 0.0057 0.028 0.1491
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0055 0.0268 0.1452
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0067 0.0354 0.0407
Brugia malayi Cathepsin L-like precursor 0.0157 0.0997 0.5823
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0033 0.011 0.0469
Giardia lamblia Hypothetical protein 0.0033 0.011 0.0736

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.051 uM Inhibition of human platelet PDE5 by [3H]cGMP scintillation proximity assay ChEMBL. 17337182
IC50 (binding) = 0.051 uM Inhibition of human platelet PDE5 by [3H]cGMP scintillation proximity assay ChEMBL. 17337182
IC50 (binding) = 0.247 uM Inhibition of bovine PDE6 by [3H]cGMP scintillation proximity assay ChEMBL. 17337182

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.