Detailed information for compound 454255

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 347.328 | Formula: C18H13N5O3
  • H donors: 2 H acceptors: 6 LogP: 3.27 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1ccc(c(c1)C(=O)O)NC(=O)c1nn(nc1C)c1ccccc1
  • InChi: 1S/C18H13N5O3/c1-11-16(22-23(21-11)13-5-3-2-4-6-13)17(24)20-15-8-7-12(10-19)9-14(15)18(25)26/h2-9H,1H3,(H,20,24)(H,25,26)
  • InChiKey: PHWULYHAFYPALU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0289 0.0553
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Echinococcus multilocularis transient receptor potential cation channel 0.0029 0.0167 0.0157
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0018 0.006 0.0058
Schistosoma mansoni opsin-like receptor 0.0087 0.0705 0.0705
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0064 0.0489 0.048
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0015 0.0033 0.0122
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Schistosoma mansoni neuropeptide receptor 0.0087 0.0705 0.0705
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0087 0.0705 0.0696
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0084 0.0074
Schistosoma mansoni organic anion transporter 0.0064 0.0489 0.0489
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0306 0.2729 0.5837
Loa Loa (eye worm) steroid hormone receptor 0.0044 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0029 0.0167 0.0157
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0986 0.904 0.904
Trypanosoma brucei unspecified product 0.004 0.0262 0.0959
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.1124 0.4119
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0306 0.2729 0.5837
Schistosoma mansoni ap endonuclease 0.0039 0.0256 0.0256
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0044 0.03 0.03
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.006 0.0219
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0015 0.0033 0.0033
Brugia malayi glutathione reductase 0.0044 0.0298 0.0298
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0018 0.006 0.0058
Echinococcus granulosus RUN 0.0023 0.0104 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.006 0.0058
Echinococcus multilocularis hyperpolarization activated cyclic 0.0029 0.0167 0.0157
Leishmania major cathepsin L-like protease 0.0035 0.0216 0.0678
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0312 0.2787 0.278
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0161 0.1387 0.1387
Echinococcus granulosus follistatin 0.0044 0.03 0.029
Loa Loa (eye worm) glutathione reductase 0.0044 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0044 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Plasmodium vivax glutathione reductase, putative 0.0044 0.0298 0.1091
Echinococcus multilocularis allatostatin A receptor 0.0087 0.0705 0.0696
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0599 0.2195
Echinococcus granulosus transcription factor Dp 1 0.0044 0.0302 0.0292
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0023 0.0105 0.0095
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0105 0.0095
Loa Loa (eye worm) hypothetical protein 0.0064 0.0489 0.0489
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0029 0.0167 0.0179
Echinococcus granulosus fatty acid amide hydrolase 1 0.0131 0.1112 0.1103
Echinococcus multilocularis ryanodine receptor 44f 0.0029 0.0167 0.0157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0216 0.0396
Brugia malayi nuclear hormone receptor family member nhr-6 0.0021 0.0084 0.0084
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0015 0.0033 0.0023
Echinococcus multilocularis voltage gated potassium channel 0.0029 0.0167 0.0157
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0087 0.0705 0.0696
Leishmania major DNA polymerase kappa, putative 0.0024 0.0119 0.0316
Onchocerca volvulus 0.0033 0.02 0.0253
Schistosoma mansoni amine GPCR 0.0087 0.0705 0.0705
Echinococcus granulosus transient receptor potential cation channel 0.0029 0.0167 0.0157
Echinococcus multilocularis fmrfamide receptor 0.0087 0.0705 0.0696
Schistosoma mansoni microtubule-associated protein tau 0.0795 0.7271 0.7271
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0043 0.0289 1
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.006 0.0049
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0312 0.2787 0.2787
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0087 0.0705 0.0705
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0599 0.2195
Echinococcus multilocularis lamin 0.0031 0.0182 0.0171
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.006 0.006
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0262 0.0959
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0674 0.6146 0.6146
Schistosoma mansoni neuropeptide receptor 0.0087 0.0705 0.0705
Brugia malayi prostaglandin transporter 0.0064 0.0489 0.0489
Echinococcus granulosus cathepsin l1 0.0035 0.0216 0.0206
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0064 0.0489 0.048
Mycobacterium ulcerans hypothetical protein 0.0306 0.2729 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0087 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0064 0.0489 0.0489
Echinococcus granulosus neuropeptide s receptor 0.0087 0.0705 0.0696
Schistosoma mansoni amine GPCR 0.0087 0.0705 0.0705
Echinococcus multilocularis cpg binding protein 0.0035 0.0218 0.0208
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0289 0.1058
Echinococcus multilocularis potassium voltage gated channel protein 0.0029 0.0167 0.0157
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0216 0.0216
Entamoeba histolytica hypothetical protein 0.0045 0.0313 0.1144
Schistosoma mansoni calcium-activated potassium channel 0.0029 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0064 0.0489 0.0489
Echinococcus granulosus sex peptide receptor 0.0087 0.0705 0.0696
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0986 0.904 0.904
Brugia malayi Transient-receptor-potential like protein 0.0029 0.0167 0.0167
Toxoplasma gondii protein c14orf29, putative 0.0018 0.006 0.0533
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0256 0.0934
Echinococcus multilocularis microtubule associated protein 2 0.0795 0.7271 0.7268
Schistosoma mansoni coup transcription factor 0.0044 0.0298 0.0298
Echinococcus multilocularis glutamyl tRNA(Gln) amidotransferase subunit A 0.0131 0.1112 0.1103
Onchocerca volvulus 0.0087 0.0705 0.1354
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0216 0.0396
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0084 0.0084
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0256 0.0938
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.1124 0.4119
Schistosoma mansoni thyroid hormone receptor 0.0044 0.0298 0.0298
Toxoplasma gondii protease inhibitor PI2 0.0044 0.03 0.2694
Echinococcus multilocularis dna polymerase kappa 0.0047 0.0332 0.0322
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0087 0.0705 0.0705
Schistosoma mansoni peptidase 0.0018 0.006 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.006 0.0219
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0044 0.03 0.03
Trypanosoma cruzi Serine peptidase, Clan SC, Family S09X, putative 0.0018 0.006 0.0221
Loa Loa (eye worm) hypothetical protein 0.003 0.0176 0.0176
Trypanosoma cruzi cysteine peptidase, putative 0.0133 0.1124 0.4119
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0018 0.006 0.0221
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.1089 1 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0064 0.0484 0.0474
Echinococcus multilocularis monoacylglycerol lipase abhd12 0.0018 0.006 0.005
Echinococcus granulosus potassium large conductance calcium activated 0.0029 0.0167 0.0157
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Echinococcus granulosus somatostatin receptor 0.0087 0.0705 0.0696
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0216 0.0396
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0312 0.2787 0.278
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0029 0.0167 0.0167
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0332 0.1218
Leishmania major cathepsin L-like protease 0.0035 0.0216 0.0678
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Echinococcus granulosus calcium activated potassium channel 0.0029 0.0167 0.0157
Loa Loa (eye worm) G-protein coupled receptor 0.0087 0.0705 0.0705
Mycobacterium leprae PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) 0.0131 0.1112 0.3308
Onchocerca volvulus 0.0064 0.0489 0.0883
Echinococcus granulosus thyroid hormone receptor alpha 0.0021 0.0084 0.0074
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0256 0.0246
Echinococcus granulosus FTZ F1 alpha 0.0044 0.0298 0.0288
Onchocerca volvulus 0.0515 0.4669 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0044 0.0298 0.0298
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0105 0.0105
Schistosoma mansoni agrin 0.0044 0.03 0.03
Echinococcus multilocularis transient receptor potential cation channel 0.0031 0.0185 0.0175
Leishmania major phosphopantetheinyl transferase-like protein 0.0045 0.0313 0.1039
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0064 0.0484 0.0474
Loa Loa (eye worm) voltage-gated calcium channel 0.0029 0.0167 0.0167
Brugia malayi Calcitonin receptor-like protein seb-1 0.0986 0.904 0.904
Brugia malayi Pre-SET motif family protein 0.0451 0.4074 0.4074
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.0216 0.0678
Echinococcus granulosus peptide allatostatin:somatostatin 0.0087 0.0705 0.0696
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0332 0.1218
Toxoplasma gondii cathepsin CPL 0.0035 0.0216 0.1937
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.1124 0.4119
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0216 0.0288
Loa Loa (eye worm) G-protein coupled receptor 0.0087 0.0705 0.0705
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0044 0.0298 0.0288
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.006 0.0214
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0306 0.2729 0.5837
Plasmodium vivax PST-A protein 0.0306 0.2729 1
Plasmodium falciparum BEM46-like protein, putative 0.0018 0.006 0.01
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0029 0.0167 0.0167
Trypanosoma cruzi cytochrome P450, putative 0.0018 0.006 0.022
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0064 0.0489 0.0489
Brugia malayi Cathepsin L-like precursor 0.0035 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0057 0.0419 0.0419
Trypanosoma cruzi cysteine peptidase, putative 0.0133 0.1124 0.4119
Mycobacterium tuberculosis Possible lysophospholipase 0.0306 0.2729 1
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0018 0.006 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0087 0.0705 0.0705
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0029 0.0167 0.0157
Echinococcus granulosus rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Brugia malayi hypothetical protein 0.0087 0.0705 0.0705
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0071 0.0548 0.0538
Schistosoma mansoni retinoic acid receptor RXR 0.0044 0.0298 0.0298
Echinococcus granulosus potassium voltage gated channel protein 0.0029 0.0167 0.0157
Schistosoma mansoni growth hormone secretagogue receptor 0.0087 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0084
Brugia malayi putative neuropeptide receptor NPR1 0.0087 0.0705 0.0705
Loa Loa (eye worm) voltage-gated potassium channel 0.0029 0.0167 0.0167
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0087 0.0705 0.0705
Entamoeba histolytica cysteine protease, putative 0.0018 0.006 0.0214
Brugia malayi Cytochrome P450 family protein 0.0018 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Mycobacterium tuberculosis Probable reductase 0.0099 0.0816 0.2903
Entamoeba histolytica cysteine protease, putative 0.0018 0.006 0.0214
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Echinococcus granulosus Polycystic kidney disease protein 0.0023 0.0104 0.0094
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.0216 0.0678
Brugia malayi putative neuropeptide receptor 0.0087 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Echinococcus granulosus intermediate filament protein 0.0031 0.0182 0.0171
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0023 0.0105 0.0105
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0029 0.0167 0.149
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0044 0.0298 0.0288
Plasmodium falciparum alpha/beta hydrolase fold domain containing protein, putative 0.0018 0.006 0.01
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0131 0.1111 0.1102
Echinococcus granulosus g protein coupled receptor 0.0087 0.0705 0.0696
Plasmodium falciparum exported lipase 1 0.0018 0.006 0.01
Loa Loa (eye worm) cysteine protease 0.0035 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0084
Onchocerca volvulus 0.0044 0.0298 0.0467
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Echinococcus multilocularis G protein coupled receptor 139 0.0087 0.0705 0.0696
Trichomonas vaginalis conserved hypothetical protein 0.0306 0.2729 0.5837
Loa Loa (eye worm) hypothetical protein 0.0044 0.0298 0.0298
Echinococcus multilocularis potassium large conductance calcium activated 0.0029 0.0167 0.0157
Plasmodium vivax PST-A protein 0.0018 0.006 0.0221
Echinococcus multilocularis neuropeptide s receptor 0.0087 0.0705 0.0696
Schistosoma mansoni neuropeptide f receptor 76f 0.0087 0.0705 0.0705
Brugia malayi larval opioid receptor 0.0087 0.0705 0.0705
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0044 0.0298 0.0298
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0009 0.0009
Brugia malayi olfactory channel protein osm-9 0.0031 0.0185 0.0185
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0114 0.0956 0.0946
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0256 0.0482
Plasmodium vivax hypothetical protein, conserved 0.0018 0.006 0.0221
Toxoplasma gondii esterase/lipase/thioesterase domain-containing protein 0.0018 0.006 0.0533
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0029 0.0167 0.0157
Brugia malayi hypothetical protein 0.0087 0.0705 0.0705
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.0289 0.0289
Brugia malayi Dopamine receptor 0.0087 0.0705 0.0705
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0029 0.0167 0.0167
Plasmodium vivax thioredoxin reductase, putative 0.0044 0.0298 0.1091
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0087 0.0705 0.0705
Schistosoma mansoni amine GPCR 0.0087 0.0705 0.0705
Leishmania major cathepsin L-like protease 0.0133 0.1124 0.4046
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0099 0.0816 0.2903
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0104 0.0094
Brugia malayi GnHR receptor homolog 0.0087 0.0705 0.0705
Entamoeba histolytica cysteine protease, putative 0.0018 0.006 0.0214
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0029 0.0167 0.0167
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0499 0.4482
Brugia malayi Serotonin receptor 0.0087 0.0705 0.0705
Trypanosoma cruzi monoglyceride lipase, putative 0.0306 0.2729 1
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0216 0.0792
Brugia malayi Doublecortin family protein 0.0023 0.0104 0.0104
Mycobacterium ulcerans hydrolase 0.0018 0.006 0.01
Loa Loa (eye worm) nuclear receptor NHR-67 0.0021 0.0084 0.0084
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0071 0.0548 0.0548
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0033 0.0122
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.006 0.0218
Loa Loa (eye worm) agrin synaptic family protein 0.0044 0.03 0.03
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.006 0.0057
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.006
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0146 0.0145
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0044 0.0298 0.0467
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.006 0.006
Brugia malayi nuclear hormone receptor 0.0021 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0023 0.0105 0.0105
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0087 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0256 0.0246
Loa Loa (eye worm) fibroinase 0.0035 0.0216 0.0216
Brugia malayi Cyclic-nucleotide gated cation channel 0.0029 0.0167 0.0167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.1124 0.4119
Plasmodium falciparum esterase, putative 0.0306 0.2729 1
Entamoeba histolytica cysteine proteinase 2 0.0018 0.006 0.0214
Echinococcus multilocularis neuropeptide FF receptor 2 0.0087 0.0705 0.0696
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0306 0.2729 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0332 0.1218
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0216 0.0396
Trypanosoma brucei hypothetical protein, conserved 0.0045 0.0313 0.1148
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0087 0.0705 0.0696
Loa Loa (eye worm) histone methyltransferase 0.0013 0.001 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0044 0.0298 0.0298
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0044 0.03 0.03
Onchocerca volvulus Neuropeptide F receptor homolog 0.0087 0.0705 0.1354
Loa Loa (eye worm) hypothetical protein 0.0161 0.1387 0.1387
Echinococcus granulosus monoacylglycerol lipase abhd12 0.0018 0.006 0.005
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0289 0.1058
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0044 0.0298 0.0288
Schistosoma mansoni voltage-gated ion channel 0.0029 0.0167 0.0167
Brugia malayi putative amidase 0.0131 0.1112 0.1112
Schistosoma mansoni DNA helicase recq1 0.0023 0.0105 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0216 0.0396
Schistosoma mansoni lamin 0.0031 0.0182 0.0182
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0087 0.0705 0.0696
Schistosoma mansoni nuclear receptor 0.0021 0.0084 0.0084
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0216 0.0788
Plasmodium vivax lysophospholipase, putative 0.0018 0.006 0.0221
Plasmodium vivax lysophospholipase, putative 0.0018 0.006 0.0221
Loa Loa (eye worm) hypothetical protein 0.0043 0.0289 0.0289
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0044 0.0298 0.0298
Echinococcus granulosus potassium voltage gated channel protein 0.0029 0.0167 0.0157
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0105 0.0936
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0029 0.0167 0.0167
Echinococcus granulosus rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Brugia malayi sodium-independent organic anion transporter family protein 0.0064 0.0489 0.0489
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0332 0.1218
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.006 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0216 0.0396
Echinococcus granulosus GPCR family 2 0.0312 0.2787 0.278
Trypanosoma brucei DNA polymerase IV, putative 0.0047 0.0332 0.1218
Leishmania major hypothetical protein, conserved 0.0018 0.006 0.01
Plasmodium vivax vivapain-2 0.0035 0.0216 0.0792
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Brugia malayi Cathepsin L-like precursor 0.0035 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0044 0.0298 0.0298
Schistosoma mansoni thyroid hormone receptor 0.0044 0.0298 0.0298
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0029 0.0167 0.0167
Schistosoma mansoni opsin-like receptor 0.0087 0.0705 0.0705
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0029 0.0167 0.0167
Brugia malayi hypothetical protein 0.0023 0.0107 0.0107
Onchocerca volvulus Putative organic anion transporter 0.0064 0.0489 0.0883
Echinococcus multilocularis short transient receptor potential channel 6 0.0031 0.0185 0.0175
Loa Loa (eye worm) hypothetical protein 0.0044 0.03 0.03
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0047 0.0332 0.0647
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0105 0.0266
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0023 0.0105 0.0095
Entamoeba histolytica cysteine proteinase 1, putative 0.0018 0.006 0.0214
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0044 0.0298 0.0298
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0131 0.1111 0.1102
Entamoeba histolytica cysteine protease, putative 0.0018 0.006 0.0214
Leishmania major cathepsin L-like protease 0.0035 0.0216 0.0678
Loa Loa (eye worm) hypothetical protein 0.0023 0.0109 0.0109
Entamoeba histolytica cysteine protease, putative 0.0018 0.006 0.0214
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0216 0.0216
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0044 0.0298 0.0298
Echinococcus granulosus fmrfamide receptor 0.0087 0.0705 0.0696
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0109 0.0165
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0029 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0023 0.0107 0.0107
Giardia lamblia Sgs1 DNA helicase, putative 0.0023 0.0105 0.2811
Plasmodium falciparum glutathione reductase 0.0044 0.0298 0.098
Echinococcus granulosus short transient receptor potential channel 6 0.0029 0.0167 0.0157
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.006
Brugia malayi secreted modular calcium-binding protein 1 0.0044 0.03 0.03
Loa Loa (eye worm) neuropeptide F receptor 0.0087 0.0705 0.0705
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0023 0.0105 0.0095
Trypanosoma cruzi major cysteine proteinase, putative 0.0104 0.0861 0.3153
Echinococcus granulosus neuropeptides capa receptor 0.0087 0.0705 0.0696
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0018 0.006 0.0221
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0071 0.0258
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0499 0.0499
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0076 0.0599 0.0599
Plasmodium falciparum epoxide hydrolase 2 0.0018 0.006 0.01
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0087 0.0705 0.0696
Onchocerca volvulus 0.0087 0.0705 0.1354
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0015 0.0033 0.0023
Onchocerca volvulus 0.0035 0.0216 0.0288
Brugia malayi Cathepsin L-like precursor 0.0035 0.0216 0.0216
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0216 0.0206
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0084 0.0084
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0044 0.0298 0.0298
Brugia malayi G-protein coupled receptor 0.0087 0.0705 0.0705
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0105 0.0155
Echinococcus granulosus L aminoadipate semialdehyde 0.0161 0.1387 0.1378
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0087 0.0705 0.0696
Brugia malayi follicle stimulating hormone receptor 0.0087 0.0705 0.0705
Loa Loa (eye worm) neuropeptide F receptor 0.0087 0.0705 0.0705
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0029 0.0167 0.0157
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Schistosoma mansoni opsin-like receptor 0.0087 0.0705 0.0705
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0044 0.03 0.2694
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0044 0.0298 0.0298
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0114 0.0956 0.0946
Trypanosoma cruzi cysteine peptidase, putative 0.0133 0.1124 0.4119
Onchocerca volvulus 0.0064 0.0489 0.0883
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.006 0.0058
Brugia malayi latrophilin 2 splice variant baaae 0.0674 0.6146 0.6146
Echinococcus granulosus potassium voltage gated channel protein 0.0029 0.0167 0.0157
Echinococcus granulosus allatostatin A receptor 0.0087 0.0705 0.0696
Loa Loa (eye worm) TYRA-2 protein 0.0087 0.0705 0.0705
Mycobacterium ulcerans amidase 0.0131 0.1112 0.4003
Loa Loa (eye worm) ion channel NompC 0.0029 0.0167 0.0167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0216 0.0396
Echinococcus multilocularis musashi 0.0031 0.0182 0.0171
Echinococcus multilocularis rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Brugia malayi neuropeptide F receptor 0.0087 0.0705 0.0705
Schistosoma mansoni hypothetical protein 0.0023 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0084
Schistosoma mansoni vesicular amine transporter 0.0029 0.0167 0.0167
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0044 0.0298 0.0288
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0289 0.0553
Mycobacterium ulcerans aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0131 0.1112 0.4003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0084
Toxoplasma gondii hypothetical protein 0.0018 0.006 0.0533
Schistosoma mansoni fatty-acid amide hydrolase 0.0131 0.1112 0.1112
Echinococcus granulosus histone lysine methyltransferase setb 0.0065 0.0499 0.0489
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.1111 0.1111
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0015 0.0033 0.0123
Echinococcus granulosus sodium channel protein 0.0029 0.0167 0.0157
Brugia malayi hypothetical protein 0.0087 0.0705 0.0705
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0332 0.1218
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0015 0.0033 0.0122
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0029 0.0167 0.0167
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0087 0.0705 0.0696
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0044 0.0298 0.0298
Echinococcus multilocularis sodium channel protein 0.0029 0.0167 0.0157
Echinococcus multilocularis neuropeptide receptor A26 0.0087 0.0705 0.0696
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0029 0.0167 0.0157
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0031 0.0185 0.0185
Brugia malayi orphan nuclear receptor NR2E1 0.0021 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Echinococcus multilocularis neuropeptides capa receptor 0.0087 0.0705 0.0696
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0071 0.0548 0.1909
Schistosoma mansoni cpg binding protein 0.0033 0.02 0.02
Loa Loa (eye worm) doublecortin family protein 0.0023 0.0104 0.0104
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0087 0.0705 0.0696
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.006 0.0214
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0044 0.0298 0.0298
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.06 0.5463 0.5463
Echinococcus granulosus hyperpolarization activated cyclic 0.0029 0.0167 0.0157
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0084 0.0084
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0029 0.0167 0.0167
Plasmodium vivax vivapain-3 0.0018 0.006 0.0218
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0087 0.0705 0.0705
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0044 0.0298 0.0288
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0161 0.1387 0.1387
Plasmodium vivax PST-A protein 0.0018 0.006 0.0221
Brugia malayi steroid hormone receptor 0.0044 0.0298 0.0298
Plasmodium falciparum glutamyl-tRNA(Gln) amidotransferase subunit A 0.0131 0.1112 0.4003
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Plasmodium falciparum lysophospholipase, putative 0.0018 0.006 0.01
Echinococcus multilocularis two pore calcium channel protein 2 0.0029 0.0167 0.0157
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0076 0.0599 0.0589
Schistosoma mansoni amidase 0.1089 1 1
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0182 0.0182
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0298 0.0288
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0087 0.0705 0.0705
Schistosoma mansoni hypothetical protein 0.0312 0.2787 0.2787
Trypanosoma cruzi serine peptidase, putative 0.0018 0.006 0.0221
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0029 0.0167 0.0157
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0306 0.2729 0.5837
Echinococcus multilocularis shaker cognate 0.0029 0.0167 0.0157
Echinococcus granulosus Phospholipase carboxylesterase 0.0018 0.006 0.005
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0071 0.0548 0.1909
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0087 0.0705 0.0705
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0033 0.0122
Entamoeba histolytica cysteine protease, putative 0.0018 0.006 0.0214
Echinococcus granulosus neuropeptides capa receptor 0.0087 0.0705 0.0696
Schistosoma mansoni myosin xvIII 0.0087 0.0705 0.0705
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0071 0.0548 0.1909
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0045 0.0313 0.1039
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0029 0.0167 0.0157
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.006
Schistosoma mansoni biogenic amine (5HT) receptor 0.0087 0.0705 0.0705
Plasmodium vivax SET domain protein, putative 0.0065 0.0499 0.1827
Leishmania major cysteine peptidase A (CPA) 0.0035 0.0216 0.0678
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0216 0.0396
Plasmodium falciparum exported lipase 2 0.0018 0.006 0.01
Brugia malayi MGC79044 protein 0.0018 0.006 0.006
Schistosoma mansoni ap endonuclease 0.0039 0.0256 0.0256
Onchocerca volvulus Cathepsin F homolog 0.0035 0.0216 0.0288
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0105 0.0936
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0084 0.0074
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0499 0.0489
Trypanosoma cruzi amidase, putative 0.0131 0.1112 0.4076
Schistosoma mansoni nuclear receptor nhr-48 0.0021 0.0084 0.0084
Plasmodium falciparum esterase, putative 0.0018 0.006 0.01
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0087 0.0705 0.0696
Schistosoma mansoni neuropeptide receptor 0.0087 0.0705 0.0705
Brugia malayi hypothetical protein 0.0087 0.0705 0.0705
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0029 0.0167 0.0157
Echinococcus multilocularis hyperpolarization activated cyclic 0.0029 0.0167 0.0157
Echinococcus multilocularis neuropeptide Y receptor 0.0087 0.0705 0.0696
Plasmodium vivax unspecified product 0.0018 0.006 0.0221
Echinococcus granulosus Solute carrier organic anion transporter family 0.0064 0.0489 0.048
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0076 0.0599 0.0599
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0084 0.0074
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.02 0.02
Loa Loa (eye worm) amidase 0.0131 0.1112 0.1112
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.006 0.0058
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0256 0.0938
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0418 0.3773 0.3773
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0018 0.006 0.0058
Brugia malayi Melatonin receptor type 1A 0.0087 0.0705 0.0705
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0045 0.0313 0.2595
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0087 0.0705 0.0705
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0114 0.0956 0.0955
Plasmodium falciparum alpha/beta hydrolase, putative 0.0018 0.006 0.01
Brugia malayi Cytochrome P450 family protein 0.0018 0.006 0.006
Echinococcus multilocularis short transient receptor potential channel 6 0.0029 0.0167 0.0157
Loa Loa (eye worm) RecQ helicase 0.0023 0.0105 0.0105
Entamoeba histolytica recQ family helicase, putative 0.0023 0.0105 0.0381
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0024 0.0119 0.0316
Onchocerca volvulus 0.0031 0.0182 0.0212
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0306 0.2729 0.5837
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0015 0.0033 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.1124 0.4119
Toxoplasma gondii thioredoxin reductase 0.0044 0.0298 0.2671
Trichomonas vaginalis DNA polymerase eta, putative 0.0047 0.0332 0.0647
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0045 0.0313 0.1039
Echinococcus multilocularis dro:myosuppressin receptor 0.0087 0.0705 0.0696
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.006 0.0058
Loa Loa (eye worm) hypothetical protein 0.0023 0.0109 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0071 0.0258
Schistosoma mansoni blooms syndrome DNA helicase 0.0012 0.0001 0.0001
Schistosoma mansoni two-pore calcium channel 0.0029 0.0167 0.0167
Brugia malayi cathepsin L-like precursor 0.0023 0.0109 0.0109
Brugia malayi Cathepsin L-like precursor 0.0035 0.0216 0.0216
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0104 0.0094
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0216 0.0396
Onchocerca volvulus 0.0087 0.0705 0.1354
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0017 0.0048 0.0038
Schistosoma mansoni biogenic amine receptor 0.0087 0.0705 0.0705
Trichomonas vaginalis conserved hypothetical protein 0.0306 0.2729 0.5837
Echinococcus granulosus nuclear receptor nhr 48 0.0021 0.0084 0.0074
Onchocerca volvulus 0.0044 0.03 0.0471
Echinococcus granulosus two pore calcium channel protein 2 0.0029 0.0167 0.0157
Echinococcus multilocularis ubiquitin specific protease 41 0.0043 0.0289 0.0279
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0065 0.0499 0.0499
Echinococcus multilocularis nuclear receptor nhr 48 0.0021 0.0084 0.0074
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0029 0.0167 0.0611
Echinococcus multilocularis cysteine protease 0.0035 0.0216 0.0206
Echinococcus granulosus 7tm_1 domain containing protein 0.0087 0.0705 0.0696
Echinococcus granulosus orexin receptor type 2 0.0087 0.0705 0.0696
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0121 0.1017 0.3727
Echinococcus multilocularis follistatin 0.0044 0.03 0.029
Plasmodium vivax hypothetical protein, conserved 0.0018 0.006 0.0221
Brugia malayi Cathepsin L-like precursor 0.0023 0.0109 0.0109
Echinococcus granulosus biogenic amine 5HT receptor 0.0087 0.0705 0.0696
Onchocerca volvulus Putative organic anion transporter 0.0064 0.0489 0.0883
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.011 0.0919 0.3285
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.006
Toxoplasma gondii transporter, cation channel family protein 0.0029 0.0167 0.149
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Echinococcus granulosus sodium leak channel non selective protein 0.0029 0.0167 0.0157
Plasmodium vivax vivapain-1 0.0018 0.006 0.0218
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0087 0.0705 0.0696
Toxoplasma gondii hypothetical protein 0.0029 0.0167 0.149
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0015 0.0033 0.0123
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0226 0.0827
Giardia lamblia Cgi67 serine protease precursor-like protein 0.0018 0.006 0.1058
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0044 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0029 0.0167 0.0179
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Echinococcus granulosus voltage dependent calcium channel 0.0114 0.0956 0.0946
Brugia malayi hypothetical protein 0.0021 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0216 0.0396
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Echinococcus granulosus ubiquitin specific protease 41 0.0043 0.0289 0.0279
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0029 0.0167 0.0289
Mycobacterium ulcerans DNA polymerase IV 0.0047 0.0332 0.1109
Loa Loa (eye worm) ctsf protein 0.0035 0.0216 0.0216
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0087 0.0705 0.0705
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0087 0.0705 0.0705
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0029 0.0167 0.0167
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0018 0.006 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0216 0.0396
Mycobacterium ulcerans amidase 0.0131 0.1112 0.4003
Brugia malayi neuropeptide F receptor 0.0087 0.0705 0.0705
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.006 0.0218
Leishmania major cathepsin L-like protease 0.0133 0.1124 0.4046
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0029 0.0167 0.0167
Schistosoma mansoni neuropeptide F-like receptor 0.0087 0.0705 0.0705
Schistosoma mansoni DNA polymerase eta 0.0017 0.0048 0.0048
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0044 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0029 0.0167 0.0167
Echinococcus granulosus rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Brugia malayi ion channel NompC 0.0029 0.0167 0.0167
Plasmodium vivax glutamyl-tRNA(Gln) amidotransferase subunit A, putative 0.0131 0.1112 0.4076
Trypanosoma cruzi cytochrome P450, putative 0.0018 0.006 0.022
Echinococcus granulosus ryanodine receptor 44f 0.0029 0.0167 0.0157
Brugia malayi Cathepsin L-like precursor 0.0035 0.0216 0.0216
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0256 0.0938
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0029 0.0167 0.0167
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0029 0.0167 0.0167
Giardia lamblia DINP protein human, muc B family 0.0024 0.0119 0.3336
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0021 0.0084 0.0074
Echinococcus multilocularis serotonin receptor 0.0087 0.0705 0.0696
Echinococcus multilocularis g protein coupled receptor 0.0087 0.0705 0.0696
Echinococcus multilocularis voltage gated potassium channel 0.0029 0.0167 0.0157
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Mycobacterium tuberculosis Probable oxidoreductase 0.011 0.0919 0.3285
Onchocerca volvulus 0.0087 0.0705 0.1354
Onchocerca volvulus 0.0023 0.0104 0.0043
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0018 0.006 0.0058
Echinococcus granulosus voltage gated hydrogen channel 1 0.0029 0.0167 0.0157
Plasmodium falciparum lysophospholipase, putative 0.0306 0.2729 1
Schistosoma mansoni voltage-gated cation channel 0.0114 0.0956 0.0955
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0332 0.1218
Echinococcus multilocularis L aminoadipate semialdehyde 0.0161 0.1387 0.1378
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0084 0.0074
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0298 0.0298
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0044 0.0298 0.0288
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0021 0.0084 0.0074
Echinococcus granulosus lamin dm0 0.0031 0.0182 0.0171
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0216 0.0396
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0087 0.0705 0.0705
Plasmodium falciparum alpha/beta hydrolase, putative 0.0018 0.006 0.01
Echinococcus granulosus cathepsin L 0.0018 0.006 0.0049
Onchocerca volvulus 0.0023 0.0104 0.0043
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0216 0.0396
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0024 0.0119 0.0316
Loa Loa (eye worm) hypothetical protein 0.0023 0.0104 0.0104
Echinococcus granulosus rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Plasmodium falciparum lysophospholipase, putative 0.0306 0.2729 1
Schistosoma mansoni 60S ribosomal protein L21 0.0029 0.0167 0.0167
Brugia malayi Amidase family protein 0.0131 0.1112 0.1112
Echinococcus granulosus potassium voltage gated channel protein 0.0029 0.0167 0.0157
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0071 0.0548 0.0538
Brugia malayi Thioredoxin reductase 0.0044 0.0298 0.0298
Brugia malayi cation channel family protein 0.0029 0.0167 0.0167
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0057 0.0419 0.1535
Brugia malayi Cathepsin L-like precursor 0.0023 0.0109 0.0109
Brugia malayi ORL1-like opioid receptor 0.0087 0.0705 0.0705
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0599 0.2195
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0109 0.0165
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0029 0.0167 0.0157
Echinococcus granulosus bloom syndrome protein 0.0023 0.0105 0.0095
Mycobacterium ulcerans amidase 0.0131 0.1112 0.4003
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.006 0.0214
Echinococcus granulosus neuropeptide Y receptor 0.0087 0.0705 0.0696
Echinococcus multilocularis cysteine protease 0.0035 0.0216 0.0206
Loa Loa (eye worm) hypothetical protein 0.0986 0.904 0.904
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0216 0.0396
Entamoeba histolytica cysteine protease, putative 0.0018 0.006 0.0214
Brugia malayi hypothetical protein 0.0087 0.0705 0.0705
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0105 0.0155
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0107 0.0107
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0015 0.0033 0.0122
Schistosoma mansoni lipoxygenase 0.0023 0.0104 0.0104
Mycobacterium ulcerans hypothetical protein 0.0018 0.006 0.01
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0029 0.0167 0.0167
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0029 0.0167 0.0167
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0499 0.0499
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Brugia malayi ecdysteroid receptor 0.0044 0.0298 0.0298
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0013 0.0012 0.0095
Leishmania major trypanothione reductase 0.0044 0.0298 0.098
Mycobacterium ulcerans hypothetical protein 0.0018 0.006 0.01
Echinococcus granulosus transient receptor potential cation channel 0.0029 0.0167 0.0157
Echinococcus multilocularis abhydrolase domain containing 3 0.0018 0.006 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.1124 0.4119
Loa Loa (eye worm) hypothetical protein 0.0023 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0027
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.0216 0.0678
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0018 0.006 0.0058
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0312 0.2787 0.278
Echinococcus multilocularis thyroid hormone receptor alpha 0.0044 0.0298 0.0288
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.006 0.0218
Schistosoma mansoni fatty acid binding protein 0.004 0.0262 0.0262
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0065 0.0499 0.0489
Entamoeba histolytica cysteine protease, putative 0.0018 0.006 0.0214
Echinococcus granulosus rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Onchocerca volvulus 0.0161 0.1387 0.2841
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0017 0.0048 0.0038
Mycobacterium tuberculosis Conserved hypothetical protein 0.0018 0.006 0.01
Leishmania major cathepsin L-like protease 0.0133 0.1124 0.4046
Schistosoma mansoni cpg binding protein 0.0035 0.0218 0.0218
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0289 0.0279
Echinococcus granulosus neuropeptide receptor 0.0087 0.0705 0.0696
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Echinococcus granulosus voltage dependent calcium channel 0.0057 0.0419 0.0409
Treponema pallidum NADH oxidase 0.0015 0.0033 0.0289
Entamoeba histolytica hypothetical protein 0.0018 0.006 0.0217
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0216 0.0206
Plasmodium vivax unspecified product 0.0018 0.006 0.0218
Chlamydia trachomatis acyltransferase family protein 0.0018 0.006 0.025
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0289 0.0279
Toxoplasma gondii hypothetical protein 0.0029 0.0167 0.149
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0087 0.0705 0.0705
Schistosoma mansoni biogenic amine (5HT) receptor 0.0087 0.0705 0.0705
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0018 0.006 0.0533
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0087 0.0705 0.0705
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0029 0.0167 0.0167
Echinococcus granulosus two pore calcium channel protein 1 0.0029 0.0167 0.0157
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0057 0.0419 0.1535
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0015 0.0033 0.0122
Echinococcus granulosus lamin 0.0031 0.0182 0.0171
Chlamydia trachomatis hydrolase 0.0018 0.006 0.025
Toxoplasma gondii hypothetical protein 0.0018 0.006 0.0533
Trypanosoma cruzi serine peptidase, putative 0.0018 0.006 0.0221
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0048 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0216 0.0396
Echinococcus granulosus ecdysone induced protein 78C 0.0044 0.0298 0.0288
Brugia malayi hypothetical protein 0.0023 0.0107 0.0107
Loa Loa (eye worm) nuclear hormone receptor 0.0021 0.0084 0.0084
Onchocerca volvulus 0.0035 0.0216 0.0288
Schistosoma mansoni steroid hormone receptor ad4bp 0.0044 0.0298 0.0298
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0044 0.03 0.2694
Brugia malayi Protein C20orf22 0.0018 0.006 0.006
Onchocerca volvulus 0.0023 0.0109 0.0055
Mycobacterium ulcerans amidase 0.0131 0.1112 0.4003
Schistosoma mansoni transient receptor potential channel 0.0029 0.0167 0.0167
Echinococcus multilocularis rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Brugia malayi G protein-coupled receptor F59B2.13 0.0087 0.0705 0.0705
Echinococcus granulosus dro:myosuppressin receptor 0.0087 0.0705 0.0696
Echinococcus multilocularis FTZ F1 alpha 0.0044 0.0298 0.0288
Trichomonas vaginalis set domain proteins, putative 0.0513 0.4651 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0015 0.0033 0.0123
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0332 0.1218
Trypanosoma brucei fatty-acid amide hydrolase, putative 0.0131 0.1112 0.4076
Entamoeba histolytica cysteine protease, putative 0.0018 0.006 0.0214
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0256 0.2064
Schistosoma mansoni transient receptor potential channel 0.0031 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0029 0.0167 0.0167
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0033 0.0122
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0044 0.0298 0.098
Plasmodium falciparum cysteine proteinase falcipain 1 0.0018 0.006 0.0097
Mycobacterium tuberculosis Possible amidase (aminohydrolase) 0.0131 0.1112 0.4003
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0044 0.0298 0.0288
Trypanosoma cruzi MFS transporter, putative 0.0064 0.0489 0.1794
Echinococcus granulosus cpg binding protein 0.0035 0.0218 0.0208
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0015 0.0033 0.029
Brugia malayi cation channel family protein 0.0029 0.0167 0.0167
Echinococcus multilocularis g protein coupled receptor 0.0087 0.0705 0.0696
Loa Loa (eye worm) hypothetical protein 0.0044 0.0298 0.0298
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0087 0.0705 0.0705
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0044 0.0298 0.0298
Echinococcus granulosus dnaJ subfamily B 0.0471 0.4266 0.426
Entamoeba histolytica ;Alias 0.0018 0.006 0.0217
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.1124 0.4119
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0216 0.0206
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Echinococcus granulosus rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0017 0.0048 0.0048
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Toxoplasma gondii transporter, cation channel family protein 0.0057 0.0419 0.3763
Entamoeba histolytica cysteine protease, putative 0.0018 0.006 0.0214
Trypanosoma cruzi DNA polymerase eta, putative 0.0017 0.0048 0.0176
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0043 0.0289 0.0289
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0105 0.0105
Toxoplasma gondii hypothetical protein 0.0018 0.006 0.0533
Brugia malayi Cathepsin L-like cysteine proteinase 0.0023 0.0109 0.0109
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0084 0.0074
Echinococcus multilocularis RUN 0.0023 0.0104 0.0094
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0114 0.0956 0.0946
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0044 0.0298 0.0298
Echinococcus multilocularis neuropeptide Y receptor 0.0087 0.0705 0.0696
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0076 0.0599 0.0599
Loa Loa (eye worm) calcium channel 0.0114 0.0956 0.0955
Trypanosoma cruzi trypanothione reductase, putative 0.0015 0.0033 0.0122
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0071 0.0548 0.1909
Echinococcus multilocularis agrin 0.0044 0.03 0.029
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0087 0.0705 0.0705
Toxoplasma gondii aldehyde dehydrogenase 0.0131 0.1111 1
Echinococcus multilocularis transient receptor potential cation channel 0.0029 0.0167 0.0157
Schistosoma mansoni rab6-interacting 0.0023 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0064 0.0489 0.0489
Brugia malayi Dopamine receptor protein 1 0.0087 0.0705 0.0705
Plasmodium falciparum LCCL domain-containing protein 0.0023 0.0104 0.0262
Echinococcus multilocularis Polycystic kidney disease protein 0.0023 0.0104 0.0094
Schistosoma mansoni RAR-like nuclear receptor 0.0044 0.0298 0.0298
Brugia malayi hypothetical protein 0.0087 0.0705 0.0705
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0044 0.0298 0.0298
Plasmodium vivax PST-A protein 0.0018 0.006 0.0221
Brugia malayi nuclear receptor NHR-88 0.0044 0.0298 0.0298
Echinococcus granulosus tm gpcr rhodopsin 0.0087 0.0705 0.0696
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0332 0.1218
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0256 0.0826
Echinococcus multilocularis sex peptide receptor 0.0087 0.0705 0.0696
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Schistosoma mansoni hypothetical protein 0.0471 0.4266 0.4266
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0084
Echinococcus granulosus microtubule associated protein 2 0.0795 0.7271 0.7268
Entamoeba histolytica cysteine protease, putative 0.0018 0.006 0.0214
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Echinococcus multilocularis voltage dependent calcium channel 0.0114 0.0956 0.0946
Schistosoma mansoni hypothetical protein 0.0312 0.2787 0.2787
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0256 0.0256
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0044 0.0298 0.0298
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0044 0.0298 0.0298
Echinococcus granulosus transient receptor potential cation channel 0.0029 0.0167 0.0157
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0029 0.0167 0.0167
Brugia malayi sodium-independent organic anion transporter family protein 0.0064 0.0489 0.0489
Schistosoma mansoni lipoxygenase 0.0064 0.0484 0.0483
Plasmodium falciparum alpha/beta hydrolase, putative 0.0018 0.006 0.01
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0045 0.0313 0.2812
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0104 0.0094
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0029 0.0167 0.0157
Echinococcus multilocularis dna polymerase eta 0.0017 0.0048 0.0038
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0256 0.0826
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.006 0.0058
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0062 0.0465 0.0465
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0017 0.0048 0.0048
Toxoplasma gondii transporter, major facilitator family protein 0.0064 0.0489 0.4398
Entamoeba histolytica cysteine protease, putative 0.0018 0.006 0.0214
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0107 0.0097
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0029 0.0167 0.0157
Brugia malayi hypothetical protein 0.0087 0.0705 0.0705
Brugia malayi intermediate filament protein 0.0031 0.0182 0.0182
Echinococcus multilocularis fatty acid binding protein FABP2 0.004 0.0262 0.0252
Echinococcus multilocularis neuropeptides capa receptor 0.0087 0.0705 0.0696
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0029 0.0167 0.0157
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0216 0.0396
Echinococcus multilocularis transcription factor Dp 1 0.0044 0.0302 0.0292
Loa Loa (eye worm) hypothetical protein 0.0031 0.0182 0.0182
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0216 0.0396
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0099 0.0816 0.2903
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0021 0.0084 0.0074
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0107 0.0107
Toxoplasma gondii exonuclease III APE 0.0039 0.0256 0.2296
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0087 0.0705 0.0696
Loa Loa (eye worm) hypothetical protein 0.0017 0.0048 0.0048
Echinococcus granulosus voltage gated potassium channel 0.0029 0.0167 0.0157
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Onchocerca volvulus 0.0064 0.0489 0.0883
Onchocerca volvulus 0.0035 0.0216 0.0288
Leishmania major cathepsin L-like protease 0.0035 0.0216 0.0678
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0298 0.0288
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0045 0.0313 0.1039
Echinococcus multilocularis potassium voltage gated channel protein 0.0029 0.0167 0.0157
Echinococcus multilocularis G-protein coupled receptor, putative 0.0087 0.0705 0.0696
Echinococcus multilocularis rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Schistosoma mansoni amine GPCR 0.0087 0.0705 0.0705
Schistosoma mansoni hypothetical protein 0.0312 0.2787 0.2787
Echinococcus granulosus agrin 0.0044 0.03 0.029
Echinococcus multilocularis cathepsin L 0.0018 0.006 0.0049
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0084 0.0084
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0298 0.0288
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0216 0.0396
Echinococcus multilocularis fatty acid amide hydrolase 1 0.1089 1 1
Trypanosoma brucei Serine peptidase, Clan SC, Family S09X 0.0018 0.006 0.0221
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0044 0.0298 0.0288
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0099 0.0816 0.2903
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0216 0.0396
Brugia malayi photoreceptor-specific nuclear receptor 0.0044 0.0298 0.0298
Loa Loa (eye worm) amidase 0.0131 0.1112 0.1112
Leishmania major hypothetical protein, unknown function 0.0029 0.0167 0.0494
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.006 0.0058
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0084
Brugia malayi polk-prov protein 0.0036 0.0226 0.0226
Echinococcus granulosus fatty acid binding protein FABP2 0.004 0.0262 0.0252
Echinococcus multilocularis somatostatin receptor 0.0087 0.0705 0.0696
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0044 0.0298 0.0298
Leishmania major cytochrome p450-like protein 0.0018 0.006 0.0099
Schistosoma mansoni cathepsin F (C01 family) 0.0023 0.0109 0.0109
Loa Loa (eye worm) DR-78 0.0021 0.0084 0.0084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0332 0.1218
Echinococcus granulosus thioredoxin glutathione reductase 0.0044 0.0303 0.0293
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0105 0.0385
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.1111 0.3999
Echinococcus granulosus shaker cognate 0.0029 0.0167 0.0157
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0018 0.006 0.0099
Echinococcus multilocularis fmrfamide receptor 0.0087 0.0705 0.0696
Mycobacterium ulcerans amidase 0.0131 0.1112 0.4003
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0087 0.0705 0.0696
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0012 0.0001 0.0004
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0451 0.4074 0.4074
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0044 0.0298 0.0298
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0107 0.0107
Echinococcus multilocularis transient receptor potential cation channel 0.0031 0.0185 0.0175
Echinococcus multilocularis neuropeptide receptor 0.0087 0.0705 0.0696
Schistosoma mansoni histamine h1 receptor 0.0087 0.0705 0.0705
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.011 0.0919 0.3285
Echinococcus multilocularis rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Chlamydia trachomatis glutamyl-tRNA(Gln) amidotransferase subunit A 0.0131 0.1112 1
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0045 0.0313 0.1039
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0018 0.006 0.0217
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0029 0.0167 0.0157
Onchocerca volvulus 0.0029 0.0167 0.0179
Brugia malayi Dopamine receptor protein 2 0.0087 0.0705 0.0705
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0107 0.0107
Leishmania major hypothetical protein, conserved 0.0029 0.0167 0.0494
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0071 0.0258
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0029 0.0167 0.0157
Plasmodium falciparum prodrug activation and resistance esterase 0.0018 0.006 0.01
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0087 0.0705 0.0696
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Onchocerca volvulus 0.0087 0.0705 0.1354
Plasmodium vivax PST-A protein 0.0018 0.006 0.0221
Schistosoma mansoni hypothetical protein 0.0029 0.0167 0.0167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.1124 0.4119
Echinococcus multilocularis sodium leak channel non selective protein 0.0029 0.0167 0.0157
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Plasmodium vivax vivapain-2 0.0035 0.0216 0.0792
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0306 0.2729 0.5837
Schistosoma mansoni hypothetical protein 0.0312 0.2787 0.2787
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0032 0.0022
Echinococcus granulosus dna polymerase kappa 0.0047 0.0332 0.0322
Trypanosoma brucei DNA polymerase eta, putative 0.0017 0.0048 0.0176
Brugia malayi Amidase family protein 0.0131 0.1112 0.1112
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0216 0.0396
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0216 0.0206
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0044 0.0298 0.0298
Schistosoma mansoni hypothetical protein 0.0087 0.0705 0.0705
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0076 0.0599 0.2098
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0044 0.03 0.03
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Schistosoma mansoni terminal deoxycytidyl transferase 0.0017 0.0048 0.0048
Echinococcus granulosus transient receptor potential gamma protein 0.0029 0.0167 0.0157
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0018 0.006 0.0058
Echinococcus multilocularis transient receptor potential cation channel 0.0029 0.0167 0.0157
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0087 0.0705 0.0705
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.006 0.006
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0076 0.0599 0.2192
Leishmania major cathepsin L-like protease 0.0035 0.0216 0.0678
Loa Loa (eye worm) hypothetical protein 0.0114 0.0956 0.0955
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0018 0.006 0.0533
Schistosoma mansoni intermediate filament proteins 0.0031 0.0182 0.0182
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.0018 0.006 0.0221
Echinococcus multilocularis thioredoxin glutathione reductase 0.0044 0.0303 0.0293
Loa Loa (eye worm) hypothetical protein 0.0044 0.03 0.03
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0087 0.0705 0.0705
Onchocerca volvulus 0.0035 0.0216 0.0288
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0312 0.2787 0.278
Schistosoma mansoni hypothetical protein 0.0674 0.6146 0.6146
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0023 0.0105 0.0266
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Schistosoma mansoni hypothetical protein 0.0087 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Plasmodium vivax multidomain scavenger receptor, putative 0.0023 0.0104 0.0381
Leishmania major monoglyceride lipase, putative 0.0306 0.2729 1
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Entamoeba histolytica cysteine protease, putative 0.0035 0.0216 0.0788
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0131 0.1112 0.1103
Schistosoma mansoni transient receptor potential channel 4 0.0029 0.0167 0.0167
Echinococcus granulosus tachykinin peptides receptor 99D 0.0087 0.0705 0.0696
Loa Loa (eye worm) hypothetical protein 0.0044 0.0298 0.0298
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0087 0.0705 0.0696
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0045 0.0313 0.2809
Brugia malayi hypothetical protein 0.0064 0.0489 0.0489
Echinococcus granulosus neuropeptide receptor 0.0087 0.0705 0.0696
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Echinococcus granulosus transient receptor potential cation channel 0.0029 0.0167 0.0157
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0105 0.0385
Leishmania major Bem46-like serine peptidase,Serine peptidase, Clan SC, Family S09X 0.0018 0.006 0.01
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0298 0.0298
Brugia malayi hypothetical protein 0.0023 0.0104 0.0104
Toxoplasma gondii phospholipase 0.0018 0.006 0.0533
Brugia malayi hypothetical protein 0.0064 0.0489 0.0489
Brugia malayi sulfakinin receptor protein 0.0087 0.0705 0.0705
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0062 0.047 0.046
Echinococcus granulosus transient receptor potential cation channel 0.0031 0.0185 0.0175
Loa Loa (eye worm) hypothetical protein 0.0023 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0087 0.0705 0.0705
Brugia malayi hypothetical protein 0.0087 0.0705 0.0705
Echinococcus multilocularis transient receptor potential gamma protein 0.0029 0.0167 0.0157
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0029 0.0167 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.006 0.0058
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0076 0.0599 0.0589
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0216 0.0206
Loa Loa (eye worm) hypothetical protein 0.0312 0.2787 0.2787
Entamoeba histolytica cysteine protease, putative 0.0018 0.006 0.0214
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0087 0.0705 0.0705
Schistosoma mansoni hypothetical protein 0.0087 0.0705 0.0705
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0001 0.0004
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0015 0.0033 0.0033
Mycobacterium tuberculosis Conserved hypothetical protein 0.0017 0.0048 0.0054
Plasmodium falciparum alpha/beta hydrolase, putative 0.0018 0.006 0.01
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0023 0.0105 0.0266
Brugia malayi hypothetical protein 0.0029 0.0167 0.0167
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0499 0.0499
Loa Loa (eye worm) hypothetical protein 0.0064 0.0489 0.0489
Brugia malayi RE15519p 0.0087 0.0705 0.0705
Echinococcus granulosus cathepsin l1 0.0023 0.0109 0.0099
Schistosoma mansoni hypothetical protein 0.0087 0.0705 0.0705
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0216 0.0216
Echinococcus multilocularis transfer RNA-Gly 0.0029 0.0167 0.0157
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0029 0.0167 0.0157
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0182 0.0182
Toxoplasma gondii transporter, cation channel family protein 0.0029 0.0167 0.149
Loa Loa (eye worm) ryanodine receptor 0.0029 0.0167 0.0167
Brugia malayi MGC83647 protein 0.0018 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0032
Echinococcus granulosus short transient receptor potential channel 6 0.0031 0.0185 0.0175
Plasmodium vivax PST-A protein 0.0018 0.006 0.0221
Echinococcus granulosus transient receptor potential cation channel 0.0029 0.0167 0.0157
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0289 0.0279
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0216 0.0288
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0044 0.0298 0.0298
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0018 0.006 0.0221
Toxoplasma gondii hypothetical protein 0.0027 0.0146 0.13
Echinococcus granulosus TRP transient receptor potential channel 0.0029 0.0167 0.0157
Echinococcus granulosus alpha 1A adrenergic receptor 0.0087 0.0705 0.0696
Leishmania major DNA polymerase eta, putative 0.0017 0.0048 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0332 0.1218
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.006
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0087 0.0705 0.0705
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0043 0.0289 0.0289
Plasmodium vivax lysophospholipase, putative 0.0018 0.006 0.0221
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Echinococcus multilocularis conserved hypothetical protein 0.0029 0.0167 0.0157
Mycobacterium tuberculosis Probable amidase AmiB2 (aminohydrolase) 0.0131 0.1112 0.4003
Echinococcus multilocularis transient receptor potential cation channel 0.0029 0.0167 0.0157
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0087 0.0705 0.0705
Echinococcus granulosus biogenic amine 5HT receptor 0.0087 0.0705 0.0696
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0029 0.0167 0.0289
Brugia malayi SPARC precursor 0.0044 0.03 0.03
Onchocerca volvulus 0.0031 0.0182 0.0212
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0029 0.0167 0.0157
Schistosoma mansoni rab6-interacting 0.0023 0.0104 0.0104
Onchocerca volvulus 0.0087 0.0705 0.1354
Onchocerca volvulus 0.0065 0.0499 0.0904
Trypanosoma cruzi cysteine protease, putative 0.0018 0.006 0.0218
Loa Loa (eye worm) hypothetical protein 0.0044 0.0298 0.0298
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0087 0.0705 0.0705
Schistosoma mansoni zinc finger protein 0.0021 0.0084 0.0084
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0029 0.0167 0.0167
Onchocerca volvulus 0.0087 0.0705 0.1354
Schistosoma mansoni alpha-1 adrenergic receptor 0.0087 0.0705 0.0705
Trypanosoma brucei monoglyceride lipase, putative 0.0306 0.2729 1
Echinococcus granulosus cysteine protease 0.0018 0.006 0.0049
Brugia malayi hypothetical protein 0.0087 0.0705 0.0705
Schistosoma mansoni organic anion transporter 0.0064 0.0489 0.0489
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0048 0.0048
Schistosoma mansoni fatty-acid amide hydrolase 0.1089 1 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0044 0.0298 0.0298
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Echinococcus multilocularis dnaJ subfamily B 0.0471 0.4266 0.426
Echinococcus multilocularis rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0289 0.0553
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0029 0.0167 0.0157
Schistosoma mansoni DNA helicase recq5 0.0023 0.0105 0.0105
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0087 0.0705 0.1354
Brugia malayi nuclear receptor RXR 0.0023 0.0107 0.0107
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0087 0.0705 0.0705
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0021 0.0084 0.0084
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0029 0.0167 0.0157
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Loa Loa (eye worm) latrophilin receptor protein 2 0.0312 0.2787 0.2787
Plasmodium vivax unspecified product 0.0018 0.006 0.0221
Loa Loa (eye worm) hypothetical protein 0.0044 0.0298 0.0298
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0099 0.0816 0.208
Brugia malayi G protein-coupled receptor 0.0087 0.0705 0.0705
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0044 0.0298 0.0288
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0256 0.0826
Loa Loa (eye worm) CYP4Cod1 0.0018 0.006 0.006
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0087 0.0705 0.0705
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0107 0.0097
Echinococcus multilocularis two pore calcium channel protein 1 0.0029 0.0167 0.0157
Schistosoma mansoni neuropeptide receptor 0.0087 0.0705 0.0705
Onchocerca volvulus Bile acid receptor homolog 0.0044 0.0298 0.0467
Echinococcus granulosus neuropeptide FF receptor 2 0.0087 0.0705 0.0696
Loa Loa (eye worm) voltage-dependent calcium channel 0.0057 0.0419 0.0419
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0029 0.0167 0.0167
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0087 0.0705 0.0705
Echinococcus multilocularis fatty acid amide hydrolase 1 0.1089 1 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0146 0.0145
Echinococcus multilocularis rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.1111 0.3999
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.006 0.006
Brugia malayi nuclear receptor NHR-67 0.0021 0.0084 0.0084
Loa Loa (eye worm) voltage-gated potassium channel 0.0029 0.0167 0.0167
Echinococcus granulosus neuropeptide Y receptor 0.0087 0.0705 0.0696
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0029 0.0167 0.0167
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0029 0.0167 0.0157
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0087 0.0705 0.0705
Echinococcus multilocularis g-protein coupled receptor 0.0087 0.0705 0.0696
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0216 0.0396
Loa Loa (eye worm) hypothetical protein 0.0036 0.0226 0.0226
Echinococcus granulosus abhydrolase domain containing 3 0.0018 0.006 0.005
Trypanosoma brucei cytochrome P450, putative 0.0018 0.006 0.022
Schistosoma mansoni biogenic amine receptor 0.0087 0.0705 0.0705
Echinococcus multilocularis calcium activated potassium channel 0.0029 0.0167 0.0157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0216 0.0396
Schistosoma mansoni lamin 0.0031 0.0182 0.0182
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0114 0.0956 0.0946
Onchocerca volvulus 0.0087 0.0705 0.1354
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0119 0.0434
Brugia malayi Tachykinin-like peptides receptor 99D 0.0087 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0044 0.03 0.03
Echinococcus granulosus hypothetical protein 0.0029 0.0167 0.0157
Treponema pallidum aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0131 0.1112 1
Onchocerca volvulus 0.0087 0.0705 0.1354
Leishmania major hypothetical protein, conserved 0.0131 0.1112 0.4003
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0029 0.0167 0.0157
Echinococcus multilocularis fatty acid binding protein FABP2 0.004 0.0262 0.0252
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Onchocerca volvulus 0.0035 0.0216 0.0288
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.1111 0.1111
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.006 0.0058
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0073 0.0567 0.0567
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0018 0.006 0.0058
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0109 0.0397
Schistosoma mansoni nuclear receptor 0.0021 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0044 0.0298 0.0298
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0114 0.0956 0.0955
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0045 0.0313 0.2595
Plasmodium falciparum alpha/beta-hydrolase, putative 0.0018 0.006 0.01
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0029 0.0167 0.0167
Schistosoma mansoni fatty acid binding protein 0.004 0.0262 0.0262
Brugia malayi nuclear hormone receptor 0.0044 0.0298 0.0298
Echinococcus multilocularis lamin dm0 0.0031 0.0182 0.0171
Loa Loa (eye worm) hypothetical protein 0.0023 0.0104 0.0104
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0033 0.0122
Onchocerca volvulus 0.0087 0.0705 0.1354
Schistosoma mansoni cpg binding protein 0.0035 0.0218 0.0218
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0087 0.0705 0.0696
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0029 0.0167 0.0167
Echinococcus granulosus glutamyl tRNAGln amidotransferase subunit A 0.0131 0.1112 0.1103
Schistosoma mansoni glutamyl-tRNA(Gln) amidotransferase subunit A 0.0131 0.1112 0.1112
Echinococcus granulosus abhydrolase domain containing protein 13 0.0018 0.006 0.005
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0114 0.0956 0.0946
Echinococcus multilocularis g protein coupled receptor 0.0087 0.0705 0.0696
Brugia malayi Cathepsin L-like precursor 0.0035 0.0216 0.0216
Echinococcus granulosus tm gpcr rhodopsin 0.0087 0.0705 0.0696
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.1124 0.4119
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0029 0.0167 0.0167
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0029 0.0167 0.0157
Mycobacterium tuberculosis Probable amidase AmiD (acylamidase) (acylase) 0.0131 0.1112 0.4003
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0029 0.0167 0.0167
Trypanosoma cruzi cruzipain precursor, putative 0.0133 0.1124 0.4119
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.1124 0.4119
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0029 0.0167 0.0157
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0064 0.0489 0.0489
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0027
Brugia malayi hypothetical protein 0.0087 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Trypanosoma brucei trypanothione reductase 0.0044 0.0298 0.1091
Echinococcus multilocularis neuropeptide receptor 0.0087 0.0705 0.0696
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Schistosoma mansoni follistatin 0.0044 0.03 0.03
Echinococcus granulosus rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Echinococcus multilocularis expressed protein 0.0044 0.03 0.029
Onchocerca volvulus 0.0087 0.0705 0.1354
Onchocerca volvulus Putative organic anion transporter 0.0064 0.0489 0.0883
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Echinococcus multilocularis Phospholipase carboxylesterase 0.0018 0.006 0.005
Echinococcus granulosus hyperpolarization activated cyclic 0.0029 0.0167 0.0157
Schistosoma mansoni neuropeptide F-like receptor 0.0087 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0084
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0021 0.0084 0.0084
Brugia malayi nuclear hormone receptor family member odr-7 0.0021 0.0084 0.0084
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0087 0.0705 0.0705
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0029 0.0167 0.149
Brugia malayi voltage-dependent calcium channel 0.0029 0.0167 0.0167
Brugia malayi Latrophilin receptor protein 2 0.0312 0.2787 0.2787
Plasmodium falciparum thioredoxin reductase 0.0044 0.0298 0.098
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0289 0.1058
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0256 0.8724
Echinococcus multilocularis potassium voltage gated channel protein 0.0029 0.0167 0.0157
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0029 0.0167 0.0157
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0018 0.006 0.0221
Plasmodium falciparum alpha/beta hydrolase, putative 0.0018 0.006 0.01
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Brugia malayi tailless protein 0.0021 0.0084 0.0084
Brugia malayi Steroid receptor seven-up type 2 0.0044 0.0298 0.0298
Mycobacterium ulcerans DNA polymerase IV 0.0047 0.0332 0.1109
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0044 0.0298 0.0298
Brugia malayi conserved hypotetical protein 0.0021 0.0084 0.0084
Brugia malayi hypothetical protein 0.0021 0.0084 0.0084
Schistosoma mansoni voltage-dependent calcium channel 0.0029 0.0167 0.0167
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0256 0.0826
Echinococcus granulosus g protein coupled receptor 0.0087 0.0705 0.0696
Echinococcus granulosus serotonin receptor 0.0087 0.0705 0.0696
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.0497 0.4466
Onchocerca volvulus Protein ultraspiracle homolog 0.0044 0.0298 0.0467
Onchocerca volvulus 0.0064 0.0489 0.0883
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0084
Echinococcus granulosus hypothetical protein 0.0087 0.0705 0.0696
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.006 0.0218
Trypanosoma brucei DNA polymerase IV, putative 0.0047 0.0332 0.1218
Loa Loa (eye worm) hypothetical protein 0.0035 0.0216 0.0216
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0105 0.0155
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0107 0.0107
Trypanosoma brucei monoglyceride lipase, putative 0.0306 0.2729 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0107 0.0107
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0306 0.2729 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0087 0.0705 0.0696
Plasmodium falciparum esterase, putative 0.0018 0.006 0.01
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0044 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Onchocerca volvulus 0.0087 0.0705 0.1354
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0332 0.1218
Loa Loa (eye worm) hypothetical protein 0.0023 0.0107 0.0107
Echinococcus granulosus neuropeptide receptor A26 0.0087 0.0705 0.0696
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0029 0.0167 0.0157
Mycobacterium tuberculosis Probable amidase AmiA2 (aminohydrolase) 0.0131 0.1112 0.4003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0044 0.0298 0.0298
Plasmodium falciparum lysophospholipase, putative 0.0306 0.2729 1
Onchocerca volvulus 0.0087 0.0705 0.1354
Onchocerca volvulus 0.0087 0.0705 0.1354
Brugia malayi AKH receptor 0.0087 0.0705 0.0705
Mycobacterium ulcerans lysophospholipase 0.0306 0.2729 1
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.06 0.5463 0.5463
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.0289 0.1054
Schistosoma mansoni ryanodine receptor related 0.0029 0.0167 0.0167
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0332 0.1218
Mycobacterium leprae PROBABLE AMIDASE AMIC (AMINOHYDROLASE) 0.0131 0.1112 0.3308
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0216 0.0206
Echinococcus granulosus fatty acid binding protein FABP2 0.004 0.0262 0.0252
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0018 0.006 0.0221
Echinococcus granulosus potassium voltage gated channel protein 0.0029 0.0167 0.0157
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.006 0.0214
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0289 0.0279
Trypanosoma cruzi trypanothione reductase, putative 0.0044 0.0298 0.1091
Toxoplasma gondii NADPH-glutathione reductase 0.0015 0.0033 0.029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.006 0.0057
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0029 0.0167 0.0167
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0499 0.0499
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0033 0.0122
Echinococcus multilocularis GPCR, family 2 0.0312 0.2787 0.278
Echinococcus granulosus G protein coupled receptor 139 0.0087 0.0705 0.0696
Onchocerca volvulus 0.0087 0.0705 0.1354
Mycobacterium ulcerans peptide amidase, GatA 0.0131 0.1112 0.4003
Echinococcus granulosus tm gpcr rhodopsin 0.0087 0.0705 0.0696
Loa Loa (eye worm) hypothetical protein 0.0044 0.03 0.03
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0029 0.0167 0.0157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0216 0.0396
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0023 0.0105 0.0095
Entamoeba histolytica hypothetical protein 0.0018 0.006 0.0217
Plasmodium falciparum lysophospholipase, putative 0.0018 0.006 0.01
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0114 0.0956 0.0955
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0087 0.0705 0.0696
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0071 0.0548 0.0548
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0064 0.0489 0.048
Echinococcus multilocularis voltage dependent calcium channel 0.0114 0.0956 0.0946
Schistosoma mansoni adenoreceptor 0.0087 0.0705 0.0705
Brugia malayi nuclear receptor NHR-88 0.0021 0.0084 0.0084
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0298 0.0288
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0029 0.0167 0.0167
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0131 0.1111 0.3999
Schistosoma mansoni polycystin 1-related 0.0023 0.0104 0.0104
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0131 0.1111 0.3999
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Trypanosoma cruzi amidase, putative 0.0131 0.1112 0.4076
Schistosoma mansoni transient receptor potential channel 0.0029 0.0167 0.0167
Mycobacterium tuberculosis Probable amidase AmiC (aminohydrolase) 0.0131 0.1112 0.4003
Onchocerca volvulus 0.0087 0.0705 0.1354
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0226 0.0827
Schistosoma mansoni amine GPCR 0.0087 0.0705 0.0705
Schistosoma mansoni nuclear hormone receptor 0.0044 0.0298 0.0298
Schistosoma mansoni loxhd1 0.0023 0.0104 0.0104
Echinococcus granulosus g protein coupled receptor 0.0087 0.0705 0.0696
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0045 0.0313 0.1148
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0256 0.0482
Onchocerca volvulus 0.0087 0.0705 0.1354
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0029 0.0167 0.0494
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0216 0.0396
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0332 0.1218
Onchocerca volvulus 0.0064 0.0489 0.0883
Brugia malayi G-protein coupled receptor 0.0087 0.0705 0.0705
Echinococcus granulosus fatty acid amide hydrolase 1 0.1089 1 1
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0306 0.2729 1
Schistosoma mansoni biogenic amine receptor 0.0087 0.0705 0.0705
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0087 0.0705 0.0696
Echinococcus granulosus fatty acid amide hydrolase 1 0.1089 1 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0256 0.2293
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0032 0.0022
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0087 0.0705 0.0705
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0021 0.0084 0.0084
Brugia malayi sodium-independent organic anion transporter family protein 0.0064 0.0489 0.0489
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0018 0.006 0.0058
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0114 0.0956 0.0946
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0044 0.03 0.03
Entamoeba histolytica deoxycytidyl transferase, putative 0.0017 0.0048 0.0171
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0033 0.0122
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0044 0.03 0.2694
Echinococcus multilocularis rhodopsin orphan GPCR 0.0087 0.0705 0.0696
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0043 0.0289 0.0947
Onchocerca volvulus 0.0035 0.0216 0.0288
Loa Loa (eye worm) thioredoxin reductase 0.0044 0.0298 0.0298
Brugia malayi Serotonin receptor 0.0087 0.0705 0.0705
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0104 0.0094
Echinococcus multilocularis ecdysone induced protein 78C 0.0044 0.0298 0.0288
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0105 0.0105
Toxoplasma gondii peptidase S15, putative 0.0018 0.006 0.0533
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0114 0.0956 0.0946
Onchocerca volvulus 0.0035 0.0216 0.0288
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0044 0.03 0.2694
Echinococcus granulosus voltage gated potassium channel 0.0029 0.0167 0.0157
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0087 0.0705 0.0696
Toxoplasma gondii hypothetical protein 0.0018 0.006 0.0533
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0064 0.0489 0.0489
Leishmania major hypothetical protein, conserved 0.0018 0.006 0.01
Echinococcus granulosus 7TM GPCR rhodopsin 0.0087 0.0705 0.0696
Plasmodium vivax alpha/beta hydrolase, putative 0.0018 0.006 0.0221
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0216 0.0788
Brugia malayi hypothetical protein 0.0023 0.0104 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0216 0.0396
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0256 0.0938
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0084
Echinococcus multilocularis orexin receptor type 2 0.0087 0.0705 0.0696
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0029 0.0167 0.0157
Echinococcus multilocularis potassium voltage gated channel protein 0.0029 0.0167 0.0157
Loa Loa (eye worm) melatonin receptor type 1A 0.0087 0.0705 0.0705
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0087 0.0705 0.0705
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0029 0.0167 0.0167
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0029 0.0167 0.0611
Brugia malayi nuclear receptor RXR 0.0021 0.0084 0.0084
Mycobacterium tuberculosis Probable dehydrogenase 0.0099 0.0816 0.2903
Toxoplasma gondii phospholipase/carboxylesterase 0.0018 0.006 0.0533
Brugia malayi CXXC zinc finger family protein 0.0033 0.02 0.02
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.1111 0.3999
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.011 0.0919 0.2506
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0167 0.0167
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0099 0.0816 0.2903
Loa Loa (eye worm) hypothetical protein 0.0023 0.0109 0.0109
Echinococcus granulosus dna polymerase eta 0.0017 0.0048 0.0038
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0018 0.006 0.006
Brugia malayi ecdysone receptor 0.0021 0.0084 0.0084
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0045 0.0313 0.2812
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0084 0.0074
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0256 0.0256
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0029 0.0167 0.0167
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0087 0.0705 0.0696
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0029 0.0167 0.0157
Echinococcus multilocularis serotonin receptor 0.0087 0.0705 0.0696
Brugia malayi Pre-SET motif family protein 0.0065 0.0499 0.0499
Plasmodium vivax alpha/beta hydrolase, putative 0.0018 0.006 0.0221
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Wolbachia endosymbiont of Brugia malayi aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0131 0.1112 1
Echinococcus granulosus g-protein coupled receptor 0.0087 0.0705 0.0696
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0167
Plasmodium vivax hypothetical protein, conserved 0.0018 0.006 0.0221
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.1124 0.4119
Loa Loa (eye worm) hypothetical protein 0.0087 0.0705 0.0705
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0216 0.0216

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 4 ug ml-1 Antibacterial activity against Staphylococcus aureus UC 9218 ChEMBL. 17350254
MIC (functional) > 128 ug ml-1 Antibacterial activity against Staphylococcus aureus UC 9218 in presence of 10% human serum ChEMBL. 17350254

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.