Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | purinergic receptor P2Y, G-protein coupled, 2 | Starlite/ChEMBL | References |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | = 221 nM | Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assay | ChEMBL. | 17011188 |
EC50 (functional) | = 221 nM | Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assay | ChEMBL. | 17011188 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.