Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | adenosine deaminase-related | 0.0086 | 0.4925 | 0.0865 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.0132 | 1 | 1 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0086 | 0.4925 | 0.5 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0132 | 1 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0086 | 0.4925 | 0.4925 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.0132 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.4925 | 0.3788 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0086 | 0.4925 | 0.4925 |
Echinococcus granulosus | adenosylhomocysteinase | 0.0132 | 1 | 1 |
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.0132 | 1 | 1 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.0132 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0132 | 1 | 1 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.0132 | 1 | 1 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.0132 | 1 | 1 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.0132 | 1 | 1 |
Plasmodium falciparum | adenosylhomocysteinase | 0.0132 | 1 | 1 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0132 | 1 | 0.5 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.0132 | 1 | 1 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.0132 | 1 | 1 |
Schistosoma mansoni | adenosine deaminase | 0.0086 | 0.4925 | 0.0865 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.0132 | 1 | 0.5 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0132 | 1 | 0.5 |
Treponema pallidum | adenosine deaminase | 0.0086 | 0.4925 | 0.5 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0132 | 1 | 1 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.0132 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 25 uM | Displacement of human MDC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | ChEMBL. | 17395464 |
Ki (binding) | = 25 uM | Displacement of human MDC from recombinant CCR4 receptor expressed in CHO cells coexpressing Galpha16 by FLIPR assay | ChEMBL. | 17395464 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.