Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | cannabinoid receptor 1 (brain) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0196 | 0.2885 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0225 | 0.349 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.039 | 0.6943 | 0.6837 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0196 | 0.2885 | 0.5 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0537 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.0334 | 1 |
Onchocerca volvulus | 0.0057 | 0 | 0.5 | |
Brugia malayi | TAR-binding protein | 0.0073 | 0.0334 | 1 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0196 | 0.2885 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.0009 | 0.0284 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.0334 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0009 | 0.0284 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0196 | 0.2885 | 0.5 |
Brugia malayi | RNA binding protein | 0.0073 | 0.0334 | 1 |
Echinococcus multilocularis | tumor protein p63 | 0.039 | 0.6943 | 0.6837 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.0334 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0073 | 0.0334 | 1 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0196 | 0.2885 | 0.5 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0196 | 0.2885 | 0.5 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0537 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.0334 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0073 | 0.0334 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0537 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0073 | 0.0334 | 1 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0196 | 0.2885 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0073 | 0.0334 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.0334 | 1 |
Trichomonas vaginalis | hypothetical protein | 0.0196 | 0.2885 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.