Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | neuropeptide receptor | 0.0033 | 0.0774 | 0.0758 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0012 | 0.0146 | 0.2586 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0225 | 0.0208 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | tar DNA binding protein | 0.0142 | 0.3992 | 0.3982 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0774 | 0.0824 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0313 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0774 | 0.0824 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.001 | 0.0073 | 0.0056 |
Brugia malayi | Death domain containing protein | 0.0015 | 0.0221 | 0.0222 |
Brugia malayi | Smad1 | 0.0009 | 0.0059 | 0.0046 |
Schistosoma mansoni | amine GPCR | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | Protein kinase domain containing protein | 0.0015 | 0.0221 | 0.0222 |
Brugia malayi | Dopamine receptor protein 2 | 0.0033 | 0.0774 | 0.0824 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0024 | 0.0493 | 0.0477 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0493 | 0.0477 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0774 | 0.0824 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0032 | 0.0746 | 1 |
Loa Loa (eye worm) | glutaminase | 0.0318 | 0.9194 | 0.9193 |
Mycobacterium ulcerans | glutaminase | 0.0318 | 0.9194 | 1 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.001 | 0.0073 | 0.5 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0015 | 0.0221 | 0.0205 |
Schistosoma mansoni | biogenic amine receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0015 | 0.0225 | 0.0208 |
Brugia malayi | G-protein coupled receptor | 0.0033 | 0.0774 | 0.0824 |
Treponema pallidum | heat shock protein 90 | 0.001 | 0.0073 | 0.5 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | histamine h1 receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0033 | 0.0774 | 0.0758 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Echinococcus granulosus | neuropeptide receptor | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0221 | 0.0205 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | follicle stimulating hormone receptor | 0.0033 | 0.0774 | 0.0824 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Leishmania major | importin beta-1 subunit, putative | 0.0026 | 0.0565 | 1 |
Brugia malayi | Serotonin receptor | 0.0033 | 0.0774 | 0.0824 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0313 | 0.0322 |
Brugia malayi | Uncoordinated protein 44 | 0.0015 | 0.0221 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0009 | 0.0059 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0015 | 0.0221 | 0.0205 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0009 | 0.0059 | 0.0042 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0085 | 0.2312 | 0.2299 |
Trichomonas vaginalis | heat shock protein, putative | 0.001 | 0.0073 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | tar DNA-binding protein | 0.0142 | 0.3992 | 0.3982 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0033 | 0.0774 | 0.0824 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0012 | 0.0146 | 0.2586 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | neuropeptide receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | biogenic amine receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0012 | 0.0146 | 0.2586 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | sex peptide receptor | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | hypothetical protein | 0.0067 | 0.177 | 0.191 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0033 | 0.0774 | 0.0758 |
Trichomonas vaginalis | ran, putative | 0.0024 | 0.0493 | 0.0528 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0009 | 0.0059 | 0.0042 |
Brugia malayi | heat shock protein 90 | 0.0012 | 0.0146 | 0.014 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0033 | 0.0774 | 0.0824 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0075 | 0.2002 | 0.1988 |
Echinococcus granulosus | heat shock protein 90 | 0.001 | 0.0073 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0059 | 0.0042 |
Brugia malayi | Melatonin receptor type 1A | 0.0033 | 0.0774 | 0.0824 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0033 | 0.0774 | 0.0758 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Echinococcus multilocularis | Smad4 | 0.0009 | 0.0059 | 0.0042 |
Schistosoma mansoni | hypothetical protein | 0.0345 | 1 | 1 |
Echinococcus multilocularis | somatostatin receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | jun-related protein | 0.0069 | 0.1839 | 0.1825 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0033 | 0.0774 | 0.4314 |
Echinococcus multilocularis | g protein coupled receptor | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0059 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | heat shock protein 90 | 0.0012 | 0.0146 | 0.0129 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | endoplasmin | 0.001 | 0.0073 | 0.0056 |
Brugia malayi | G protein-coupled receptor | 0.0033 | 0.0774 | 0.0824 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0493 | 0.0519 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | neuropeptide receptor | 0.0033 | 0.0774 | 0.0758 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0033 | 0.0774 | 0.0824 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Trypanosoma cruzi | heat shock protein 90, putative | 0.001 | 0.0073 | 0.1301 |
Brugia malayi | Dopamine receptor | 0.0033 | 0.0774 | 0.0824 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | Smad4 | 0.0009 | 0.0059 | 0.0042 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0015 | 0.0221 | 0.0205 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0774 | 0.0824 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0033 | 0.0774 | 0.0758 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0032 | 0.0746 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0012 | 0.0146 | 0.2586 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.2243 | 0.2229 |
Echinococcus granulosus | neuropeptide receptor | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0033 | 0.0774 | 0.0824 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0024 | 0.0493 | 0.579 |
Schistosoma mansoni | adenoreceptor | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0033 | 0.0774 | 0.0824 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0221 | 0.0205 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | tar DNA-binding protein | 0.0142 | 0.3992 | 0.3982 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | allatostatin A receptor | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0313 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | heat shock protein | 0.0012 | 0.0146 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | MH2 domain containing protein | 0.0134 | 0.375 | 0.4067 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0059 | 0.0042 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0313 | 0.0296 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Brugia malayi | GnHR receptor homolog | 0.0033 | 0.0774 | 0.0824 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0134 | 0.375 | 0.3739 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0746 | 0.073 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0012 | 0.0146 | 0.2586 |
Plasmodium vivax | importin-beta 2, putative | 0.0032 | 0.0746 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | Endoplasmin precursor | 0.0012 | 0.0146 | 0.014 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0033 | 0.0774 | 0.0824 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0075 | 0.2002 | 0.1988 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0033 | 0.0774 | 0.0758 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Brugia malayi | AKH receptor | 0.0033 | 0.0774 | 0.0824 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | myosin xvIII | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | g protein coupled receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | heat shock protein 90 | 0.0012 | 0.0146 | 0.0129 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Entamoeba histolytica | Ran family GTPase | 0.0024 | 0.0493 | 0.829 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0026 | 0.0565 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | netrin receptor unc5 | 0.0015 | 0.0221 | 0.0205 |
Schistosoma mansoni | amine GPCR | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | ORL1-like opioid receptor | 0.0033 | 0.0774 | 0.0824 |
Trichomonas vaginalis | heat shock protein, putative | 0.001 | 0.0073 | 0.0071 |
Echinococcus granulosus | Smad4 | 0.0009 | 0.0059 | 0.0042 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.092 | 0.0984 |
Schistosoma mansoni | amine GPCR | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0313 | 0.0296 |
Brugia malayi | Dopamine receptor protein 1 | 0.0033 | 0.0774 | 0.0824 |
Brugia malayi | RNA, U transporter 1 | 0.0092 | 0.2509 | 0.2716 |
Schistosoma mansoni | ran | 0.0024 | 0.0493 | 0.0477 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | sulfakinin receptor protein | 0.0033 | 0.0774 | 0.0824 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0313 | 0.0296 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0493 | 1 |
Echinococcus granulosus | neuropeptide s receptor | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0012 | 0.0146 | 0.0129 |
Brugia malayi | RNA binding protein | 0.0142 | 0.3992 | 0.4331 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0.1443 | 0.1554 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0059 | 0.0046 |
Onchocerca volvulus | Netrin receptor homolog | 0.0015 | 0.0221 | 0.1165 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0015 | 0.0221 | 0.0205 |
Echinococcus granulosus | heat shock protein | 0.0012 | 0.0146 | 0.0129 |
Brugia malayi | Serotonin receptor | 0.0033 | 0.0774 | 0.0824 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0033 | 0.0774 | 0.0758 |
Trichomonas vaginalis | heat shock protein, putative | 0.001 | 0.0073 | 0.0071 |
Echinococcus granulosus | smad | 0.0009 | 0.0059 | 0.0042 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0033 | 0.0774 | 0.0758 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0012 | 0.0146 | 0.173 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0134 | 0.375 | 0.3739 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0085 | 0.2312 | 0.2299 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Schistosoma mansoni | glutaminase | 0.0318 | 0.9194 | 0.9193 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0313 | 0.0322 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | glutaminase DH11.1 | 0.0318 | 0.9194 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0313 | 0.0296 |
Echinococcus multilocularis | fmrfamide receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Trichomonas vaginalis | heat shock protein, putative | 0.0012 | 0.0146 | 0.015 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.001 | 0.0073 | 0.5 |
Echinococcus granulosus | endoplasmin | 0.001 | 0.0073 | 0.0056 |
Echinococcus multilocularis | fmrfamide receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0033 | 0.0774 | 0.0758 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0493 | 0.8732 |
Loa Loa (eye worm) | RNA binding protein | 0.0142 | 0.3992 | 0.3982 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Echinococcus granulosus | g-protein coupled receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | somatostatin receptor | 0.0033 | 0.0774 | 0.0758 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | neuropeptide receptor | 0.0033 | 0.0774 | 0.0758 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.001 | 0.0073 | 0.5 |
Brugia malayi | RE15519p | 0.0033 | 0.0774 | 0.0824 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Brugia malayi | hypothetical protein | 0.0033 | 0.0774 | 0.0824 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0009 | 0.0059 | 0.0042 |
Echinococcus multilocularis | tar DNA binding protein | 0.0142 | 0.3992 | 0.3982 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0774 | 0.0824 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0032 | 0.0746 | 0.073 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0033 | 0.0774 | 0.0824 |
Echinococcus multilocularis | serotonin receptor | 0.0033 | 0.0774 | 0.0758 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0032 | 0.0746 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0.1443 | 0.1428 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0493 | 0.579 |
Schistosoma mansoni | amine GPCR | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | jun protein | 0.0085 | 0.2312 | 0.2299 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | neuropeptide receptor | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0313 | 0.0296 |
Schistosoma mansoni | importin beta-1 | 0.0032 | 0.0746 | 0.073 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0009 | 0.0059 | 0.0042 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0015 | 0.0221 | 0.0205 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | larval opioid receptor | 0.0033 | 0.0774 | 0.0824 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0026 | 0.0565 | 0.0606 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.1443 | 0.1554 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | allatostatin A receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | tar DNA-binding protein | 0.0142 | 0.3992 | 0.3982 |
Schistosoma mansoni | opsin-like receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0774 | 0.0824 |
Schistosoma mansoni | neuropeptide receptor | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | Smad1 | 0.0009 | 0.0059 | 0.0042 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0493 | 0.6577 |
Loa Loa (eye worm) | glutaminase 2 | 0.0318 | 0.9194 | 0.9193 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0313 | 0.0296 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1443 | 0.1428 |
Echinococcus multilocularis | sex peptide receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0313 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | endoplasmin | 0.0012 | 0.0146 | 0.0129 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0345 | 1 | 1 |
Echinococcus granulosus | jun protein | 0.0085 | 0.2312 | 0.2299 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | tar DNA-binding protein | 0.0142 | 0.3992 | 0.3982 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | TAR-binding protein | 0.0142 | 0.3992 | 0.4331 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0142 | 0.3992 | 0.4331 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0033 | 0.0774 | 0.0758 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0774 | 0.0824 |
Loa Loa (eye worm) | TAR-binding protein | 0.0142 | 0.3992 | 0.3982 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0009 | 0.0059 | 0.0042 |
Echinococcus granulosus | g protein coupled receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | death domain containing protein | 0.0015 | 0.0221 | 0.0205 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | tar DNA-binding protein | 0.0142 | 0.3992 | 0.3982 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0313 | 0.0296 |
Echinococcus granulosus | g protein coupled receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | biogenic amine receptor | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0142 | 0.3992 | 0.3982 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | G-protein coupled receptor | 0.0033 | 0.0774 | 0.0824 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | endoplasmin | 0.0012 | 0.0146 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | opsin-like receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | opsin-like receptor | 0.0033 | 0.0774 | 0.0758 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Echinococcus multilocularis | neuropeptide s receptor | 0.0033 | 0.0774 | 0.0758 |
Trichomonas vaginalis | glutaminase, putative | 0.0318 | 0.9194 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | neuropeptide F receptor | 0.0033 | 0.0774 | 0.0824 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | putative neuropeptide receptor | 0.0033 | 0.0774 | 0.0824 |
Echinococcus multilocularis | heat shock protein 90 | 0.001 | 0.0073 | 0.0056 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0774 | 0.0824 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | Importin beta-1 subunit | 0.0032 | 0.0746 | 0.0794 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Onchocerca volvulus | 0.0067 | 0.177 | 1 | |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0059 | 0.0046 |
Echinococcus granulosus | serotonin receptor | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0033 | 0.0774 | 0.0758 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | amine GPCR | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0774 | 0.0824 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0313 | 0.0296 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0493 | 0.8732 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.001 | 0.0073 | 0.1301 |
Trichomonas vaginalis | importin beta-1, putative | 0.0026 | 0.0565 | 0.0606 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0033 | 0.0774 | 0.4314 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.1839 | 0.1825 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0024 | 0.0493 | 0.0477 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0313 | 0.0296 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0015 | 0.0221 | 0.0205 |
Echinococcus multilocularis | Ankyrin | 0.0015 | 0.0225 | 0.0208 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | smad | 0.0009 | 0.0059 | 0.0042 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0009 | 0.0059 | 0.0042 |
Schistosoma mansoni | heat shock protein | 0.0012 | 0.0146 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | serotonin receptor | 0.0033 | 0.0774 | 0.0758 |
Leishmania major | GTP-binding protein, putative | 0.0024 | 0.0493 | 0.8543 |
Brugia malayi | neuropeptide F receptor | 0.0033 | 0.0774 | 0.0824 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0026 | 0.0565 | 0.0606 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | importin subunit beta 1 | 0.0032 | 0.0746 | 0.073 |
Echinococcus multilocularis | smad | 0.0009 | 0.0059 | 0.0042 |
Onchocerca volvulus | 0.0033 | 0.0774 | 0.4314 | |
Schistosoma mansoni | ran | 0.0024 | 0.0493 | 0.0477 |
Brugia malayi | bZIP transcription factor family protein | 0.0085 | 0.2312 | 0.2501 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0059 | 0.0042 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0024 | 0.0493 | 0.579 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.092 | 0.0904 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | snurportin 1 | 0.0345 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0033 | 0.0774 | 0.0758 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0059 | 0.0046 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0015 | 0.0221 | 0.0222 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0033 | 0.0774 | 0.0824 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | fmrfamide receptor | 0.0033 | 0.0774 | 0.0758 |
Plasmodium falciparum | heat shock protein 90 | 0.0012 | 0.0146 | 0.1869 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Loa Loa (eye worm) | endoplasmin | 0.0012 | 0.0146 | 0.0129 |
Leishmania major | heat shock protein 83-1 | 0.0012 | 0.0146 | 0.1477 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0033 | 0.0774 | 0.0758 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.092 | 0.0904 |
Echinococcus granulosus | Ankyrin | 0.0015 | 0.0225 | 0.0208 |
Entamoeba histolytica | hypothetical protein | 0.0026 | 0.0565 | 1 |
Echinococcus granulosus | orexin receptor type 2 | 0.0033 | 0.0774 | 0.0758 |
Echinococcus multilocularis | heat shock protein | 0.0012 | 0.0146 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0774 | 0.0758 |
Plasmodium falciparum | importin beta, putative | 0.0032 | 0.0746 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0033 | 0.0774 | 0.0758 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 49 % | Antileishmanial activity against Leishmania donovani assesed as inhibition of promastigotes at 10 ug/ml | ChEMBL. | 17548194 |
Inhibition (functional) | = 49 % | Antileishmanial activity against Leishmania donovani assesed as inhibition of promastigotes at 10 ug/ml | ChEMBL. | 17548194 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.