Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | phosphodiesterase 4A, cAMP-specific | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0129 | 0.0166 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0765 | 0.6155 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0765 | 0.6155 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0129 | 0.0166 | 0.027 |
Onchocerca volvulus | 0.0129 | 0.0166 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0129 | 0.0166 | 0.027 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0129 | 0.0166 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0765 | 0.6155 | 1 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0112 | 0 | 0.5 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0129 | 0.0166 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0765 | 0.6155 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.0166 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0765 | 0.6155 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.0166 | 0.027 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0129 | 0.0166 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.0166 | 0.027 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0765 | 0.6155 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.0166 | 0.027 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.1091 | 0.9222 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0765 | 0.6155 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0765 | 0.6155 | 1 |
Echinococcus granulosus | neuroligin | 0.0129 | 0.0166 | 0.027 |
Echinococcus multilocularis | acetylcholinesterase | 0.0765 | 0.6155 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0765 | 0.6155 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0765 | 0.6155 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0129 | 0.0166 | 0.027 |
Schistosoma mansoni | acetylcholinesterase | 0.0129 | 0.0166 | 0.027 |
Brugia malayi | Carboxylesterase family protein | 0.0765 | 0.6155 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0129 | 0.0166 | 0.027 |
Schistosoma mansoni | gliotactin | 0.0129 | 0.0166 | 0.027 |
Loa Loa (eye worm) | carboxylesterase | 0.0129 | 0.0166 | 0.027 |
Echinococcus multilocularis | neuroligin | 0.0129 | 0.0166 | 0.027 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0129 | 0.0166 | 0.027 |
Onchocerca volvulus | 0.0129 | 0.0166 | 0.5 | |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0112 | 0 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0129 | 0.0166 | 0.027 |
Loa Loa (eye worm) | carboxylesterase | 0.0129 | 0.0166 | 0.027 |
Onchocerca volvulus | 0.0129 | 0.0166 | 0.5 | |
Onchocerca volvulus | 0.0129 | 0.0166 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.0166 | 0.027 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0129 | 0.0166 | 0.027 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0129 | 0.0166 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.0166 | 0.027 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0129 | 0.0166 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.0166 | 0.027 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0129 | 0.0166 | 0.027 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.1173 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0765 | 0.6155 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.