Detailed information for compound 459012

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 353.441 | Formula: C18H19N5OS
  • H donors: 3 H acceptors: 3 LogP: 2.69 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: NCCNc1nc2cc(sc2n2c1ncc2C)c1ccccc1CO
  • InChi: 1S/C18H19N5OS/c1-11-9-21-17-16(20-7-6-19)22-14-8-15(25-18(14)23(11)17)13-5-3-2-4-12(13)10-24/h2-5,8-9,24H,6-7,10,19H2,1H3,(H,20,22)
  • InChiKey: XGFBARHKTYXMCA-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta Starlite/ChEMBL References
Homo sapiens conserved helix-loop-helix ubiquitous kinase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0424 0.1492
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.006 0.0182 0.0336
Loa Loa (eye worm) voltage-gated potassium channel 0.0046 0.0114 0.0228
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0086 0.0304 0.0555
Toxoplasma gondii endonuclease IV APN 0.0157 0.0631 0.1284
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0064 0.0063
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0774 0.3508 0.3583
Echinococcus multilocularis calmodulin 0.0026 0.0024 0.0022
Toxoplasma gondii transporter, cation channel family protein 0.0065 0.0202 0.0409
Onchocerca volvulus 0.0219 0.0923 0.2083
Trichomonas vaginalis glucosylceramidase, putative 0.0528 0.236 0.5383
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.006 0.0182 0.0336
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0018 0.0008
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.008 0.0275 0.0279
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0146 0.0582 0.0593
Trichomonas vaginalis DNA topoisomerase II, putative 0.015 0.0599 0.1345
Echinococcus granulosus dro:myosuppressin receptor 0.0219 0.0923 0.0941
Schistosoma mansoni tyrosine kinase 0.0088 0.0312 0.0319
Echinococcus multilocularis G protein coupled receptor 139 0.0219 0.0923 0.0941
Echinococcus multilocularis short transient receptor potential channel 6 0.0046 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0082 0.0282 0.0566
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0219 0.0923 0.0941
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2167 1 1
Brugia malayi Protein cec-1. 0.0024 0.0013 0.002
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0186 0.0768 0.0783
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0219 0.0923 0.0941
Echinococcus multilocularis ATP binding cassette sub family G 0.0025 0.0016 0.0014
Trichomonas vaginalis Ferredoxin 3 0.0028 0.003 0.0039
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0023 0.0022
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0067
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Loa Loa (eye worm) hypothetical protein 0.0086 0.0304 0.0609
Echinococcus multilocularis calmodulin 0.0026 0.0024 0.0022
Mycobacterium ulcerans endonuclease IV 0.0157 0.0631 0.1952
Trypanosoma brucei DNA topoisomerase ii 0.0168 0.0685 0.067
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0046 0.0114 0.0116
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.0185
Schistosoma mansoni glutamate receptor NMDA 0.0351 0.1537 0.1571
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0037 0.0074 0.0132
Schistosoma mansoni adrenodoxin 0.0028 0.003 0.0031
Echinococcus granulosus ATP binding cassette sub family G 0.0025 0.0016 0.0014
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.0824 0.084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.038 0.0842
Plasmodium vivax ataxin-2 like protein, putative 0.0077 0.0262 0.051
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0032 0.0051 0.0106
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0028 0.003 0.0045
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0186 0.0768 0.1411
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0086 0.0085
Brugia malayi hypothetical protein 0.0219 0.0923 0.1696
Brugia malayi hypothetical protein 0.0727 0.3289 0.6053
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0186 0.0768 0.2388
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0219 0.0923 0.0943
Toxoplasma gondii LsmAD domain-containing protein 0.0077 0.0262 0.0531
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0025 0.0024
Brugia malayi hypothetical protein 0.0086 0.0304 0.0555
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.008 0.0275 0.0279
Schistosoma mansoni sodium/chloride dependent transporter 0.0089 0.0316 0.0323
Echinococcus multilocularis orexin receptor type 2 0.0219 0.0923 0.0941
Leishmania major cytochrome p450-like protein 0.006 0.0182 0.018
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0046 0.0114 0.0114
Schistosoma mansoni glutamate receptor NMDA 0.0283 0.1218 0.1244
Loa Loa (eye worm) calcium channel 0.0146 0.0582 0.1167
Schistosoma mansoni voltage-dependent calcium channel 0.0046 0.0114 0.0116
Loa Loa (eye worm) intermediate filament protein 0.0083 0.0288 0.0577
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0219 0.0923 0.0943
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0063 0.0063
Echinococcus granulosus fmrfamide receptor 0.0219 0.0923 0.0941
Leishmania major calmodulin, putative 0.0026 0.0024 0.0022
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0202 0.0405
Echinococcus multilocularis Chromobox protein 3 0.0024 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0086 0.0304 0.0609
Brugia malayi Isocitrate dehydrogenase 0.0064 0.0199 0.0362
Echinococcus multilocularis CalModulin family member (cmd 1) 0.0026 0.0024 0.0022
Leishmania major hypothetical protein, conserved 0.0037 0.0073 0.0071
Schistosoma mansoni chromobox protein 0.0086 0.0304 0.0311
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0065 0.0202 0.0205
Echinococcus multilocularis voltage gated potassium channel 0.0046 0.0114 0.0114
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0219 0.0923 0.0941
Echinococcus granulosus tyrosine protein kinase Src42A 0.008 0.0275 0.0279
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0026 0.0023 0.0036
Schistosoma mansoni transient receptor potential channel 0.0046 0.0116 0.0118
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0004 0.0005
Giardia lamblia PHD finger protein 15 0.0031 0.0047 0.0105
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0037 0.0074 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0093 0.0333 0.0734
Loa Loa (eye worm) hypothetical protein 0.0077 0.0262 0.0526
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.064 0.0653
Brugia malayi cytochrome P450 0.006 0.0182 0.0332
Brugia malayi Cytochrome P450 family protein 0.006 0.0182 0.0332
Brugia malayi G protein-coupled receptor F59B2.13 0.0219 0.0923 0.1696
Loa Loa (eye worm) hypothetical protein 0.0041 0.0093 0.0186
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0007 0.0005
Trypanosoma brucei hypothetical protein, conserved 0.0186 0.0768 0.0754
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0086 0.0084
Echinococcus multilocularis 0.006 0.0182 0.0184
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0186 0.0768 0.0754
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0086 0.0304 0.031
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0018 0.001
Echinococcus granulosus glutamate synthase 0.0186 0.0768 0.0783
Onchocerca volvulus Dual oxidase homolog 0.0148 0.0593 0.1325
Brugia malayi Doublecortin family protein 0.0082 0.0282 0.0516
Schistosoma mansoni biogenic amine receptor 0.0219 0.0923 0.0943
Echinococcus granulosus calmodulin 0.0026 0.0024 0.0022
Toxoplasma gondii isocitrate dehydrogenase 0.0064 0.0199 0.0402
Schistosoma mansoni hypothetical protein 0.0048 0.0127 0.013
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0114 0.0116
Leishmania major lanosterol 14-alpha-demethylase, putative 0.006 0.0182 0.018
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0069 0.0202
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0142 0.0562 0.0547
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0074 0.0247 0.025
Brugia malayi F/Y-rich N-terminus family protein 0.0035 0.0062 0.0111
Trichomonas vaginalis chromobox protein, putative 0.0057 0.0166 0.0351
Echinococcus multilocularis lipoxygenase domain containing protein 0.0082 0.0282 0.0286
Echinococcus multilocularis serotonin receptor 0.0606 0.2725 0.2783
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0101 0.0373 0.0821
Schistosoma mansoni intermediate filament proteins 0.0083 0.0288 0.0294
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0046 0.0114 0.0116
Schistosoma mansoni hypothetical protein 0.0035 0.0064 0.0065
Echinococcus granulosus sodium and chloride dependent glycine 0.0086 0.0304 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0248 0.054
Loa Loa (eye worm) histone methyltransferase 0.0023 0.0007 0.0012
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0041 0.009 0.0148
Toxoplasma gondii DNA topoisomerase 2, putative 0.015 0.0599 0.1219
Brugia malayi Pre-SET motif family protein 0.0843 0.383 0.705
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0046 0.0114 0.0206
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0041 0.0093 0.0168
Onchocerca volvulus 0.096 0.4374 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0054 0.0108
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.029 0.1252 0.2527
Trichomonas vaginalis glucosylceramidase, putative 0.0365 0.1601 0.3643
Schistosoma mansoni hypothetical protein 0.0219 0.0923 0.0943
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0074 0.0074
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.006 0.0182 0.0529
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0923 0.0943
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0037 0.0073 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0346 0.1514 0.3444
Trypanosoma cruzi trypanothione reductase, putative 0.1073 0.4902 0.4894
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0812 0.3685 1
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.006 0.0182 0.0336
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0053
Brugia malayi nuclear hormone receptor 0.0042 0.0097 0.0174
Onchocerca volvulus 0.0059 0.0175 0.0366
Loa Loa (eye worm) hypothetical protein 0.0024 0.0013 0.0025
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0231 0.098 0.2213
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0037 0.0055
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0424 0.0942
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0405 0.1788 0.5621
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0075 0.0142
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0037 0.0074 0.0147
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0042 0.0097 0.0097
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0064 0.0199 0.0201
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0219 0.0923 0.0941
Echinococcus multilocularis Polycystic kidney disease protein 0.0082 0.0282 0.0286
Schistosoma mansoni amine GPCR 0.0219 0.0923 0.0943
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0023 0.0008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.2766 0.6315
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0923 0.0943
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0249 0.0541
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0405 0.1788 0.5621
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0158 0.0637 0.0622
Onchocerca volvulus 0.0086 0.0304 0.0662
Echinococcus granulosus intermediate filament protein 0.0083 0.0288 0.0292
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0153 0.0614 0.1128
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0088 0.0088
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0086 0.0304 0.0616
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0186 0.0768 0.0754
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0042 0.0097 0.0193
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.006 0.0182 0.0529
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0219 0.0923 0.0943
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0097 0.0099
Plasmodium falciparum glutathione reductase 0.1073 0.4902 1
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0037 0.0073 0.0057
Schistosoma mansoni sulfide quinone reductase 0.0186 0.0768 0.0785
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0923 0.0943
Plasmodium vivax ferrodoxin reductase, putative 0.0186 0.0768 0.1545
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0219 0.0923 0.1696
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0028 0.003 0.0051
Schistosoma mansoni polycystin 1-related 0.0082 0.0282 0.0288
Giardia lamblia Fructose-bisphosphate aldolase 0.0615 0.2766 0.8726
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0156 0.0626 0.1257
Echinococcus multilocularis lamin dm0 0.0083 0.0288 0.0292
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0066 0.0132
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0122 0.047 0.0955
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0127 0.023
Brugia malayi Associated with TFs and helicases family protein 0.0024 0.0013 0.002
Schistosoma mansoni glutamate receptor kainate 0.0174 0.071 0.0726
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0164 0.0665 0.2061
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0065 0.0202 0.0207
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Schistosoma mansoni ap endonuclease 0.004 0.0086 0.0087
Echinococcus granulosus transient receptor potential cation channel 0.0046 0.0114 0.0114
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0101 0.0373 0.0821
Trypanosoma cruzi NADH dehydrogenase, putative 0.0186 0.0768 0.0754
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0037 0.0074 0.0124
Trypanosoma cruzi NADH dehydrogenase, putative 0.0186 0.0768 0.0754
Echinococcus multilocularis tyrosine protein kinase Blk 0.0072 0.0239 0.0242
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0117 0.0212
Echinococcus granulosus sodium channel protein 0.0464 0.2065 0.2109
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0114 0.0116
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0089 0.0317 0.0323
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0158 0.064 0.1283
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0146 0.0582 0.0594
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0086 0.0166
Schistosoma mansoni myosin xvIII 0.0219 0.0923 0.0943
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0065 0.0202 0.0205
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0086 0.0154
Brugia malayi Dopamine receptor protein 2 0.0219 0.0923 0.1696
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0018 0.0033
Echinococcus granulosus ryanodine receptor 44f 0.0046 0.0114 0.0115
Brugia malayi Pre-SET motif family protein 0.0122 0.047 0.0862
Loa Loa (eye worm) TK/INSR protein kinase 0.0053 0.015 0.03
Schistosoma mansoni tyrosine kinase 0.0088 0.0312 0.0319
Echinococcus granulosus Chromobox protein 3 0.0024 0.0013 0.0011
Treponema pallidum fructose-bisphosphate aldolase 0.0615 0.2766 0.8724
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0064 0.0199 0.0201
Leishmania major calmodulin, putative 0.0026 0.0024 0.0022
Echinococcus multilocularis potassium voltage gated channel protein 0.0046 0.0114 0.0114
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0186 0.0768 0.2382
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0086 0.0304 0.0308
Echinococcus granulosus tyrosine protein kinase Src42A 0.0069 0.0224 0.0227
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0168 0.0685 0.0671
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Echinococcus granulosus jun protein 0.009 0.0321 0.0326
Toxoplasma gondii transporter, cation channel family protein 0.0046 0.0114 0.0229
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0086 0.007
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0023 0.0039
Echinococcus multilocularis ecdysone induced protein 78C 0.0042 0.0097 0.0097
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0069 0.0068
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0097 0.0097
Echinococcus multilocularis survival motor neuron protein 1 0.0727 0.3289 0.3359
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0701 0.3168 1
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0186 0.0768 0.2744
Brugia malayi follicle stimulating hormone receptor 0.068 0.3069 0.5648
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0086 0.007
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0083 0.0288 0.0577
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0086 0.0071
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0146 0.0582 0.0593
Brugia malayi hypothetical protein 0.0219 0.0923 0.1696
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0701 0.3168 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0064 0.0199 0.0184
Brugia malayi protein-tyrosine kinase 0.0072 0.0239 0.0436
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0219 0.0923 0.2083
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0114 0.0116
Onchocerca volvulus 0.0219 0.0923 0.2083
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0042 0.0097 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0002 0.0002
Schistosoma mansoni protein kinase 0.0031 0.0046 0.0047
Toxoplasma gondii hypothetical protein 0.0086 0.0304 0.0616
Brugia malayi putative neuropeptide receptor NPR1 0.0219 0.0923 0.1696
Brugia malayi ORL1-like opioid receptor 0.0219 0.0923 0.1696
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.038 0.0842
Loa Loa (eye worm) hypothetical protein 0.004 0.0086 0.0171
Brugia malayi Protein kinase domain containing protein 0.0158 0.064 0.1174
Schistosoma mansoni tyrosine kinase 0.0028 0.003 0.003
Toxoplasma gondii NADPH-glutathione reductase 0.0701 0.3168 0.6461
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0028 0.003 0.0059
Schistosoma mansoni adenoreceptor 0.0219 0.0923 0.0943
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0198 0.0824 0.084
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0046 0.0114 0.0206
Mycobacterium ulcerans NADH dehydrogenase 0.0186 0.0768 0.2388
Schistosoma mansoni opsin-like receptor 0.0219 0.0923 0.0943
Schistosoma mansoni amine GPCR 0.0219 0.0923 0.0943
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0087 0.0308 0.0922
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0065 0.0202 0.0435
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.047 0.048
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0047 0.0093
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0046 0.0117 0.0102
Onchocerca volvulus 0.0046 0.0114 0.0227
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0042 0.0097 0.0193
Schistosoma mansoni RAR-like nuclear receptor 0.0042 0.0097 0.0099
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0219 0.0923 0.0941
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0064 0.0199 0.038
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0064 0.0065
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0025 0.0016 0.0014
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0424 0.0409
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0042 0.0097 0.0097
Echinococcus granulosus shaker cognate 0.0046 0.0114 0.0114
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0093 0.0154
Trypanosoma cruzi adrenodoxin precursor, putative 0.0028 0.003 0.0015
Echinococcus granulosus neuropeptides capa receptor 0.0219 0.0923 0.0941
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0297 0.1285 0.2595
Treponema pallidum sodium- and chloride- dependent transporter 0.0509 0.2271 0.7153
Loa Loa (eye worm) hypothetical protein 0.0082 0.0282 0.0566
Echinococcus multilocularis mitogen activated protein kinase 0.0158 0.0637 0.0649
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0042 0.0097 0.0174
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Trichomonas vaginalis aldehyde oxidase, putative 0.0859 0.3902 0.8922
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0405 0.1788 0.3623
Onchocerca volvulus 0.0031 0.0046 0.0071
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0042 0.0083
Trypanosoma brucei target of rapamycin kinase 3, putative 0.011 0.0414 0.0399
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Echinococcus multilocularis Chromo domain 0.0024 0.0013 0.0011
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0037 0.0038
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0024 0.0013 0.0023
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0234 0.0238
Loa Loa (eye worm) hypothetical protein 0.0841 0.3822 0.7672
Schistosoma mansoni DNA topoisomerase II 0.015 0.0599 0.0612
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.0082 0.0282 0.0288
Trypanosoma cruzi calmodulin, putative 0.0026 0.0024 0.0008
Echinococcus granulosus ATP binding cassette sub family G 0.0025 0.0016 0.0014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0097 0.0097
Loa Loa (eye worm) cytochrome P450 family protein 0.0087 0.0308 0.0617
Loa Loa (eye worm) hypothetical protein 0.0042 0.0097 0.0193
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0042 0.0097 0.0193
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0219 0.0923 0.1852
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0186 0.0768 0.1536
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0042 0.0083
Trichomonas vaginalis glucosylceramidase, putative 0.0528 0.236 0.5383
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0023 0.0007
Loa Loa (eye worm) RGC/RGC protein kinase 0.0031 0.0046 0.0092
Echinococcus multilocularis allatostatin A receptor 0.0219 0.0923 0.0941
Onchocerca volvulus 0.0117 0.0445 0.0986
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0528 0.236 0.4736
Schistosoma mansoni glutamate receptor AMPA 0.0174 0.071 0.0726
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0157 0.0631 0.1284
Leishmania major extracellular receptor, putative 0.0024 0.0015 0.0013
Giardia lamblia Glutamate synthase 0.0186 0.0768 0.2393
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0186 0.0768 0.1536
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.006 0.0182 0.0529
Onchocerca volvulus 0.0086 0.0304 0.0662
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0775 0.3511 0.6461
Schistosoma mansoni rab6-interacting 0.0082 0.0282 0.0288
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0158 0.0637 0.1296
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0086 0.0304 0.0616
Trichomonas vaginalis glutathione reductase, putative 0.0701 0.3168 0.7238
Mycobacterium ulcerans DNA gyrase subunit A 0.0032 0.0051 0.0114
Echinococcus multilocularis voltage dependent calcium channel 0.0146 0.0582 0.0593
Plasmodium vivax amine transporter, putative 0.0086 0.0304 0.0594
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0028 0.003 0.0028
Brugia malayi metabotropic glutamate receptor type 2 0.0024 0.0015 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0097 0.0174
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0046 0.0114 0.0114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0249 0.0541
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0701 0.3168 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0297 0.1285 0.3456
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Loa Loa (eye worm) hypothetical protein 0.0841 0.3822 0.7672
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0042 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0029
Giardia lamblia Kinase, CMGC MAPK 0.0158 0.0637 0.1975
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0042 0.0097 0.0097
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0701 0.3168 0.583
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0046 0.0114 0.0206
Schistosoma mansoni neuropeptide receptor 0.0219 0.0923 0.0943
Mycobacterium tuberculosis Probable reductase 0.0297 0.1285 0.2595
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Loa Loa (eye worm) hypothetical protein 0.0028 0.0032 0.0064
Trypanosoma cruzi calmodulin 0.0026 0.0024 0.0008
Brugia malayi hypothetical protein 0.0219 0.0923 0.1696
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0065 0.0202 0.0205
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0102 0.0204
Echinococcus multilocularis transient receptor potential cation channel 0.0046 0.0114 0.0114
Brugia malayi hypothetical protein 0.0085 0.0298 0.0545
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0086 0.0071
Echinococcus granulosus calmodulin 0.0026 0.0023 0.0022
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0064 0.0199 0.0183
Echinococcus granulosus survival motor neuron protein 1 0.0727 0.3289 0.3359
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0219 0.0923 0.0941
Loa Loa (eye worm) hypothetical protein 0.0157 0.0631 0.1266
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.009 0.0321 0.0326
Mycobacterium ulcerans oxygenase 0.0028 0.003 0.0045
Echinococcus multilocularis dnaJ subfamily B 0.0836 0.3795 0.3876
Loa Loa (eye worm) hypothetical protein 0.0509 0.2271 0.4559
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0042 0.0097 0.0174
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0047 0.0048
Trypanosoma brucei calmodulin 0.0026 0.0024 0.0008
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0812 0.3685 0.7508
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0135 0.053 0.0515
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0046 0.0114 0.0206
Leishmania major ferric reductase, putative 0.007 0.0226 0.0224
Schistosoma mansoni voltage-gated potassium channel 0.0166 0.0675 0.069
Brugia malayi Calcitonin receptor-like protein seb-1 0.0153 0.0614 0.1128
Echinococcus multilocularis jun protein 0.009 0.0321 0.0326
Brugia malayi hypothetical protein 0.0046 0.0114 0.0206
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0701 0.3168 0.3158
Schistosoma mansoni hypothetical protein 0.0048 0.0127 0.013
Loa Loa (eye worm) hypothetical protein 0.0081 0.0281 0.0562
Chlamydia trachomatis DNA gyrase subunit A 0.0032 0.0051 0.0106
Echinococcus multilocularis G-protein coupled receptor, putative 0.0219 0.0923 0.0941
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0037 0.0074 0.0059
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0028 0.003 0.0024
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0086 0.0148
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0186 0.0768 0.1733
Onchocerca volvulus 0.0219 0.0923 0.2083
Loa Loa (eye worm) hypothetical protein 0.0031 0.0047 0.0093
Brugia malayi Bromodomain containing protein 0.004 0.0085 0.0154
Brugia malayi hypothetical protein 0.0219 0.0923 0.1696
Trypanosoma cruzi cytochrome p450-like protein, putative 0.006 0.0182 0.0167
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0186 0.0768 0.1536
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0186 0.0768 0.2744
Echinococcus granulosus short transient receptor potential channel 6 0.0046 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0424 0.085
Mycobacterium ulcerans ferredoxin reductase 0.0186 0.0768 0.2388
Echinococcus granulosus hyperpolarization activated cyclic 0.0065 0.0202 0.0205
Toxoplasma gondii isocitrate dehydrogenase 0.0064 0.0199 0.0402
Loa Loa (eye worm) glutamate receptor 1 0.0174 0.071 0.1425
Loa Loa (eye worm) hypothetical protein 0.0186 0.0768 0.1542
Trichomonas vaginalis Ferredoxin 2 0.0028 0.003 0.0039
Echinococcus multilocularis somatostatin receptor 0.0219 0.0923 0.0941
Schistosoma mansoni histamine h1 receptor 0.0219 0.0923 0.0943
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0157 0.0631 0.1255
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.2766 0.6315
Schistosoma mansoni hypothetical protein 0.0085 0.0299 0.0306
Brugia malayi PHD-finger family protein 0.0031 0.0047 0.0083
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.0073 0.0144
Echinococcus multilocularis RUN 0.0082 0.0282 0.0286
Echinococcus granulosus allatostatin A receptor 0.0219 0.0923 0.0941
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.0824 0.084
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0028 0.003 0.0057
Trypanosoma cruzi adrenodoxin precursor, putative 0.0028 0.003 0.0015
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0186 0.0768 0.1542
Brugia malayi Transient-receptor-potential like protein 0.0046 0.0114 0.0206
Echinococcus multilocularis glutamate receptor 2 0.0174 0.071 0.0724
Leishmania major ferredoxin, 2fe-2s-like protein 0.0028 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0024 0.0013 0.0025
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0046 0.0117 0.0115
Loa Loa (eye worm) hypothetical protein 0.0042 0.0097 0.0193
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0042 0.0077
Echinococcus multilocularis glutamate receptor NMDA 0.0085 0.0295 0.03
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0186 0.0768 0.1536
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0701 0.3168 0.6453
Onchocerca volvulus 0.0148 0.0592 0.1324
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0701 0.3168 0.3158
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0138 0.0545 0.0555
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0086 0.0304 0.0555
Echinococcus granulosus tyrosine protein kinase Fyn 0.008 0.0275 0.0279
Trypanosoma cruzi calmodulin, putative 0.0026 0.0024 0.0008
Echinococcus granulosus metabotropic glutamate receptor 2 0.0024 0.0015 0.0013
Echinococcus multilocularis g protein coupled receptor 0.0219 0.0923 0.0941
Entamoeba histolytica hypothetical protein 0.0025 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0319 0.0702
Schistosoma mansoni amine GPCR 0.1094 0.4997 0.5106
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0042 0.0091
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Echinococcus granulosus rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Loa Loa (eye worm) neuropeptide F receptor 0.0219 0.0923 0.1852
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.015 0.0599 0.0611
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.006 0.0182 0.0167
Schistosoma mansoni calcium-activated potassium channel 0.0046 0.0114 0.0116
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0093 0.0333 0.0341
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0127 0.0254
Echinococcus granulosus ferredoxin 0.0028 0.003 0.0029
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0114 0.0116
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0138 0.0545 0.1933
Brugia malayi Dopamine receptor protein 1 0.0663 0.2991 0.5505
Plasmodium vivax hypothetical protein, conserved 0.0086 0.0304 0.0594
Echinococcus granulosus ecdysone induced protein 78C 0.0042 0.0097 0.0097
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0074 0.0247 0.025
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.006 0.0182 0.0336
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0251 0.0256
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1845 0.8497 0.8497
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0025 0.0016 0.0028
Loa Loa (eye worm) blistered cuticle protein 3 0.0148 0.0593 0.1189
Mycobacterium ulcerans dehydrogenase 0.0186 0.0768 0.2388
Mycobacterium ulcerans monoxygenase 0.0186 0.0768 0.2388
Toxoplasma gondii target of rapamycin (TOR), putative 0.0103 0.038 0.0772
Trypanosoma cruzi hypothetical protein, conserved 0.0186 0.0768 0.0754
Trypanosoma cruzi DNA topoisomerase II, putative 0.0142 0.0562 0.0548
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0146 0.0582 0.0594
Onchocerca volvulus 0.0219 0.0923 0.2083
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0156 0.0626 0.115
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0135 0.053 0.0515
Echinococcus granulosus sex peptide receptor 0.0219 0.0923 0.0941
Brugia malayi hypothetical protein 0.0117 0.0447 0.0819
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0046 0.0114 0.0227
Schistosoma mansoni glutamate synthase 0.0186 0.0768 0.0785
Echinococcus multilocularis neuropeptides capa receptor 0.0219 0.0923 0.0941
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0085 0.0299 0.0304
Toxoplasma gondii ferredoxin, putative 0.0028 0.003 0.0057
Chlamydia trachomatis glutamine binding protein 0.0041 0.009 0.0229
Echinococcus granulosus Polycystic kidney disease protein 0.0082 0.0282 0.0286
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0028 0.003 0.0038
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0186 0.0768 0.0783
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Echinococcus multilocularis Rac GTPase activating protein 1 0.0071 0.0232 0.0235
Brugia malayi cation channel family protein 0.0046 0.0114 0.0206
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Loa Loa (eye worm) hypothetical protein 0.0086 0.0304 0.0609
Onchocerca volvulus Calmodulin homolog 0.0026 0.0024 0.0019
Schistosoma mansoni hypothetical protein 0.0685 0.3095 0.3163
Schistosoma mansoni calmodulin 0.0026 0.0024 0.0024
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0146 0.0582 0.1068
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.006 0.0182 0.0336
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0029 0.0038 0.0037
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0046 0.0114 0.0206
Mycobacterium leprae putative cytochrome p450 0.006 0.0182 0.0448
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.03 0.1301 0.2626
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0219 0.0923 0.1696
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0067
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0138 0.0545 0.0543
Brugia malayi hypothetical protein 0.0082 0.0282 0.0516
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0219 0.0923 0.0941
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0158 0.0637 0.0623
Schistosoma mansoni rab6-interacting 0.0082 0.0282 0.0288
Schistosoma mansoni cpg binding protein 0.0064 0.0199 0.0204
Onchocerca volvulus 0.0219 0.0923 0.2083
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0065 0.0202 0.0207
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0255 0.1087 0.3399
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0078 0.0077
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0219 0.0923 0.0941
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0037 0.0074 0.0132
Brugia malayi phosphofructokinase 0.0112 0.0424 0.0777
Schistosoma mansoni coup transcription factor 0.0042 0.0097 0.0099
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0101 0.0373 0.0821
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0114 0.0116
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0219 0.0923 0.1852
Onchocerca volvulus Alhambra homolog 0.0031 0.0047 0.0073
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0046 0.0114 0.0114
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0219 0.0923 0.1696
Echinococcus multilocularis ATP binding cassette sub family G 0.0025 0.0016 0.0014
Trypanosoma brucei cytochrome P450, putative 0.0087 0.0308 0.0293
Loa Loa (eye worm) hypothetical protein 0.0024 0.0013 0.0025
Trypanosoma brucei PAB1-binding protein , putative 0.0077 0.0262 0.0247
Brugia malayi Cytochrome P450 family protein 0.0087 0.0308 0.0563
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0157 0.0631 0.1264
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0146 0.0582 0.0594
Brugia malayi G-protein coupled receptor 0.0219 0.0923 0.1696
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Schistosoma mansoni microtubule-associated protein tau 0.2121 0.9787 1
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0032 0.0051 0.0068
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0007 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0923 0.0943
Schistosoma mansoni tyrosine kinase 0.008 0.0275 0.028
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0186 0.0768 0.2388
Schistosoma mansoni hypothetical protein 0.0073 0.0242 0.0247
Echinococcus multilocularis neuropeptide s receptor 0.1159 0.5302 0.5417
Trichomonas vaginalis PIKK family atypical protein kinase 0.0083 0.0286 0.0626
Loa Loa (eye worm) programmed cell death 8 0.0186 0.0768 0.1542
Toxoplasma gondii selenide, water dikinase 0.0186 0.0768 0.1564
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0064 0.0199 0.0197
Toxoplasma gondii Erv1 / Alr family protein 0.0037 0.0073 0.0144
Echinococcus multilocularis voltage dependent calcium channel 0.0146 0.0582 0.0593
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0297 0.1285 0.2595
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.006 0.0182 0.0529
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0075 0.0142
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0086 0.0214
Loa Loa (eye worm) RGC/RGC protein kinase 0.0031 0.0046 0.0092
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0515 0.2301 0.4234
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0186 0.0768 0.1733
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.008 0.0275 0.0279
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0046 0.0114 0.0206
Brugia malayi ion channel NompC 0.0046 0.0114 0.0206
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0069 0.0123
Giardia lamblia DNA topoisomerase II 0.0142 0.0563 0.1742
Entamoeba histolytica hypothetical protein 0.0096 0.0349 0.1219
Echinococcus multilocularis transient receptor potential cation channel 0.0046 0.0114 0.0114
Echinococcus granulosus cpg binding protein 0.0064 0.0199 0.0202
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0086 0.0304 0.031
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0424 0.0433
Loa Loa (eye worm) hypothetical protein 0.0775 0.3511 0.7047
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0004 0.0005
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0084 0.029 0.0632
Plasmodium vivax DNA gyrase subunit A, putative 0.0032 0.0051 0.0079
Echinococcus multilocularis shaker cognate 0.0046 0.0114 0.0114
Echinococcus multilocularis lamin 0.0083 0.0288 0.0292
Mycobacterium ulcerans electron transfer protein FdxB 0.0028 0.003 0.0045
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0041 0.0093 0.0246
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0075 0.0142
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.007 0.0226 0.0211
Brugia malayi RhoGAP domain containing protein 0.0071 0.0232 0.0424
Schistosoma mansoni tyrosine kinase 0.0053 0.015 0.0153
Plasmodium falciparum transporter, putative 0.0086 0.0304 0.0616
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0032 0.0051 0.0101
Loa Loa (eye worm) hypothetical protein 0.0075 0.0251 0.0503
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0114 0.0116
Brugia malayi SET domain containing protein 0.003 0.004 0.007
Echinococcus multilocularis potassium large conductance calcium activated 0.0046 0.0114 0.0114
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0297 0.1285 0.2595
Echinococcus granulosus neuropeptide receptor A26 0.1159 0.5302 0.5417
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0138 0.0545 0.0531
Loa Loa (eye worm) glutamate receptor 2 0.0174 0.071 0.1425
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0135 0.053 0.0541
Echinococcus granulosus rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Trichomonas vaginalis glucosylceramidase, putative 0.0346 0.1514 0.3444
Brugia malayi Metabotropic glutamate receptor precursor. 0.0024 0.0015 0.0024
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0186 0.0768 0.2382
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0424 0.085
Chlamydia trachomatis DNA gyrase subunit B 0.0069 0.0223 0.065
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0156 0.0626 0.0638
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0112 0.0424 0.1288
Loa Loa (eye worm) hypothetical protein 0.0228 0.0963 0.1933
Brugia malayi jmjC domain containing protein 0.0102 0.0378 0.0693
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0186 0.0768 0.0783
Treponema pallidum NADH oxidase 0.0701 0.3168 1
Onchocerca volvulus 0.0219 0.0923 0.2083
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.006 0.0182 0.0529
Echinococcus multilocularis lipoxygenase domain containing protein 0.0082 0.0282 0.0286
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.2766 0.6315
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.006 0.0182 0.0336
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0018 0.0002
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0138 0.0545 0.1
Schistosoma mansoni jun-related protein 0.0073 0.0242 0.0247
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0097 0.0099
Echinococcus multilocularis nmda type glutamate receptor 0.0199 0.083 0.0846
Loa Loa (eye worm) voltage-dependent calcium channel 0.0065 0.0202 0.0405
Echinococcus granulosus voltage dependent calcium channel 0.0146 0.0582 0.0593
Schistosoma mansoni voltage-gated potassium channel 0.0056 0.0162 0.0166
Brugia malayi GnHR receptor homolog 0.0219 0.0923 0.1696
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0042 0.0066
Echinococcus multilocularis sodium and chloride dependent glycine 0.0086 0.0304 0.0308
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0086 0.0166
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0065 0.0202 0.0406
Trichomonas vaginalis glucosylceramidase, putative 0.0346 0.1514 0.3444
Loa Loa (eye worm) glutamate receptor 0.0024 0.0015 0.0029
Plasmodium falciparum heterochromatin protein 1 0.0024 0.0013 0.0023
Leishmania major ATP-dependent phosphofructokinase 0.0112 0.0424 0.0422
Brugia malayi PHD-finger family protein 0.0029 0.0037 0.0064
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0026 0.0023 0.0008
Brugia malayi CHD4 protein 0.0029 0.0038 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0249 0.0541
Brugia malayi putative neuropeptide receptor 0.0219 0.0923 0.1696
Loa Loa (eye worm) hypothetical protein 0.0054 0.0151 0.0303
Echinococcus granulosus neuropeptide FF receptor 2 0.0219 0.0923 0.0941
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0086 0.0171
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.03 0.1301 0.3498
Echinococcus multilocularis hyperpolarization activated cyclic 0.0065 0.0202 0.0205
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0024 0.0015 0.0013
Echinococcus granulosus biogenic amine 5HT receptor 0.1392 0.6386 0.6524
Schistosoma mansoni hypothetical protein 0.0031 0.0047 0.0048
Echinococcus multilocularis hyperpolarization activated cyclic 0.0065 0.0202 0.0205
Echinococcus granulosus hypothetical protein 0.1671 0.7687 0.7854
Trypanosoma cruzi hypothetical protein, conserved 0.0186 0.0768 0.0754
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0064 0.0199 0.037
Loa Loa (eye worm) cytochrome P450 family protein 0.0087 0.0308 0.0617
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0046 0.0114 0.0114
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0219 0.0923 0.0943
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0028 0.003 0.0045
Loa Loa (eye worm) hypothetical protein 0.0054 0.0151 0.0302
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0096 0.0349 0.1219
Brugia malayi nuclear receptor NHR-88 0.0042 0.0097 0.0174
Echinococcus multilocularis ferredoxin adrenodoxin 0.0028 0.003 0.0029
Schistosoma mansoni hypothetical protein 0.0085 0.0299 0.0306
Onchocerca volvulus 0.0219 0.0923 0.2083
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0086 0.0304 0.031
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0086 0.0304 0.0308
Echinococcus granulosus adenylate cyclase 9 0.0084 0.029 0.0295
Trichomonas vaginalis PIKK family atypical protein kinase 0.0083 0.0286 0.0626
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0097 0.0174
Schistosoma mansoni neuropeptide receptor 0.0219 0.0923 0.0943
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0004 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0413 0.0918
Brugia malayi M-phase phosphoprotein, mpp8 0.0117 0.0445 0.0816
Echinococcus granulosus histone lysine methyltransferase setb 0.014 0.0552 0.0562
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0069 0.0127
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0127 0.023
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.007 0.0226 0.0211
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0024 0.0015 0.0013
Schistosoma mansoni glutamate receptor AMPA 0.0174 0.071 0.0726
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.2766 0.6315
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0053 0.015 0.0151
Treponema pallidum thioredoxin reductase (trxB) 0.0186 0.0768 0.2382
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0701 0.3168 0.6453
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0042 0.0097 0.0174
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0186 0.0768 0.2046
Echinococcus granulosus epidermal growth factor receptor 0.0088 0.0312 0.0317
Echinococcus multilocularis tyrosine protein kinase HCK 0.0064 0.0202 0.0204
Trypanosoma brucei electron transfer protein, putative 0.0028 0.003 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.006 0.0182 0.0529
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0085 0.0299 0.0304
Onchocerca volvulus Protein ultraspiracle homolog 0.0042 0.0097 0.0187
Loa Loa (eye worm) ion channel NompC 0.0046 0.0114 0.0228
Onchocerca volvulus 0.0509 0.2271 0.5176
Loa Loa (eye worm) cytochrome P450 family protein 0.0154 0.0619 0.1241
Echinococcus multilocularis voltage gated potassium channel 0.0075 0.0251 0.0255
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0104 0.0104
Loa Loa (eye worm) RGC/RGC protein kinase 0.0031 0.0046 0.0092
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0086 0.0167
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0637 0.1431
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0158 0.0637 0.0623
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0026 0.0023 0.0022
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0018 0.0016
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0102 0.0105
Onchocerca volvulus 0.0083 0.0288 0.0625
Brugia malayi AKH receptor 0.0219 0.0923 0.1696
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0065 0.0202 0.0207
Schistosoma mansoni hypothetical protein 0.0035 0.0063 0.0065
Echinococcus granulosus rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Brugia malayi Cytochrome P450 family protein 0.0087 0.0308 0.0563
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0424 0.1492
Trichomonas vaginalis glucosylceramidase, putative 0.0528 0.236 0.5383
Echinococcus multilocularis sodium and chloride dependent glycine 0.0086 0.0304 0.0308
Brugia malayi G-protein coupled receptor 0.0219 0.0923 0.1696
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0086 0.0304 0.0308
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0186 0.0768 0.0767
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0029 0.0038 0.0037
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0069 0.0053
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0088 0.0088
Echinococcus multilocularis insulin receptor 0.0053 0.015 0.0151
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Trypanosoma cruzi calmodulin 0.0026 0.0024 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0042 0.0097 0.0193
Loa Loa (eye worm) MH2 domain-containing protein 0.0244 0.1038 0.2082
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0089 0.0317 0.0579
Loa Loa (eye worm) hypothetical protein 0.0061 0.0187 0.0375
Onchocerca volvulus 0.0042 0.0097 0.0187
Loa Loa (eye worm) TK/EGFR protein kinase 0.0162 0.0657 0.1317
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0042 0.0083
Onchocerca volvulus 0.0219 0.0923 0.2083
Leishmania major hypothetical protein, conserved 0.0186 0.0768 0.0767
Echinococcus granulosus tm gpcr rhodopsin 0.1961 0.904 0.9236
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Trypanosoma brucei calmodulin 0.0026 0.0024 0.0008
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0923 0.0943
Brugia malayi cation channel family protein 0.0046 0.0114 0.0206
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0413 0.0918
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0046 0.0117 0.0102
Plasmodium vivax DNA gyrase subunit B, putative 0.0087 0.0308 0.0604
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0004 0.0005
Brugia malayi Bromodomain containing protein 0.0081 0.0277 0.0507
Onchocerca volvulus 0.0117 0.0445 0.0986
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0013 0.0023
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0042 0.0077
Loa Loa (eye worm) hypothetical protein 0.0065 0.0202 0.0406
Brugia malayi nuclear receptor RXR 0.0022 0.0004 0.0005
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0146 0.0582 0.0593
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.014 0.0552 0.0562
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0023 0.0023
Plasmodium vivax ABC transporter G family member 2, putative 0.0025 0.0016 0.0005
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0046 0.0117 0.012
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0102 0.0378 0.0385
Plasmodium falciparum glutathione reductase 0.0701 0.3168 0.6461
Echinococcus granulosus glutamate NMDA receptor subunit 0.0351 0.1537 0.1569
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.0824 0.084
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0701 0.3168 0.6461
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0219 0.0923 0.0941
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Loa Loa (eye worm) hypothetical protein 0.0117 0.0445 0.0893
Echinococcus granulosus RUN 0.0082 0.0282 0.0286
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0157 0.0631 0.1158
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Echinococcus multilocularis transient receptor potential cation channel 0.0046 0.0116 0.0116
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0812 0.3685 0.7508
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0065 0.0202 0.0205
Onchocerca volvulus 0.0082 0.0282 0.0613
Brugia malayi intermediate filament protein 0.0083 0.0288 0.0526
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0087 0.0308 0.0594
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0065 0.0202 0.0406
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0041 0.009 0.0237
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0047 0.0046
Loa Loa (eye worm) adenylyl cyclase 3 0.0084 0.029 0.0582
Mycobacterium tuberculosis Probable oxidoreductase 0.0028 0.003 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0074 0.014
Echinococcus granulosus g-protein coupled receptor 0.0219 0.0923 0.0941
Echinococcus granulosus potassium voltage gated channel protein 0.0046 0.0114 0.0114
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0064 0.0199 0.0183
Giardia lamblia Rho GAP, putative 0.0061 0.0187 0.0549
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0087 0.0308 0.0625
Echinococcus multilocularis adenylate cyclase 9 0.0084 0.029 0.0295
Schistosoma mansoni hypothetical protein 0.0186 0.0768 0.0785
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0186 0.0768 0.0767
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0031 0.0046 0.0071
Echinococcus multilocularis calcium activated potassium channel 0.0048 0.0126 0.0127
Echinococcus multilocularis neuropeptide receptor 0.0219 0.0923 0.0941
Plasmodium falciparum ferrodoxin reductase-like protein 0.0186 0.0768 0.1564
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0186 0.0768 0.0754
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0153 0.0614 0.1232
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.2766 0.6315
Echinococcus multilocularis peregrin 0.0034 0.0058 0.0058
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0186 0.0768 0.1733
Trichomonas vaginalis PIKK family atypical protein kinase 0.0082 0.0282 0.0617
Schistosoma mansoni transient receptor potential channel 4 0.0046 0.0114 0.0116
Leishmania major hypothetical protein, conserved 0.0186 0.0768 0.0767
Loa Loa (eye worm) neuropeptide F receptor 0.0219 0.0923 0.1852
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0117 0.0234
Treponema pallidum quinoline 2-oxidoreductase 0.0136 0.0537 0.1646
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.006 0.0182 0.0336
Schistosoma mansoni hypothetical protein 0.006 0.0182 0.0186
Loa Loa (eye worm) hypothetical protein 0.0073 0.0241 0.0483
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0042 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.038 0.0842
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0262 0.0531
Brugia malayi Thioredoxin reductase 0.1073 0.4902 0.9023
Onchocerca volvulus 0.0219 0.0923 0.2083
Loa Loa (eye worm) hypothetical protein 0.0201 0.0839 0.1683
Echinococcus granulosus sodium leak channel non selective protein 0.0046 0.0114 0.0114
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0075 0.0142
Trichomonas vaginalis glucosylceramidase, putative 0.0346 0.1514 0.3444
Echinococcus granulosus potassium voltage gated channel protein 0.0046 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0509 0.2271 0.4559
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0127 0.0128
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0086 0.0304 0.0906
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0069 0.0054
Schistosoma mansoni biogenic amine receptor 0.0219 0.0923 0.0943
Echinococcus granulosus neuropeptide receptor 0.0219 0.0923 0.0941
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0042 0.0097 0.0097
Loa Loa (eye worm) isocitrate dehydrogenase 0.0064 0.0199 0.0398
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0186 0.0768 0.2393
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0069 0.0068
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0085 0.0299 0.0304
Echinococcus multilocularis transcription factor Dp 1 0.0078 0.0265 0.0269
Giardia lamblia Calmodulin 0.0026 0.0024 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0023 0.0023
Trypanosoma cruzi cytochrome P450, putative 0.0087 0.0308 0.0293
Entamoeba histolytica calmodulin, putative 0.0026 0.0024 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0029
Brugia malayi glutamate synthase 0.0186 0.0768 0.1411
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0186 0.0768 0.2744
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.006 0.0182 0.0336
Brugia malayi chromobox protein homolog 3 0.0054 0.0151 0.0275
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.006 0.0182 0.0529
Loa Loa (eye worm) hypothetical protein 0.109 0.4982 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0042 0.0097 0.0097
Mycobacterium tuberculosis Probable oxidoreductase 0.0812 0.3685 0.7508
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0074 0.0247 0.025
Leishmania major hypothetical protein, unknown function 0.0046 0.0114 0.0112
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.2766 0.6315
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0042 0.0083
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0086 0.0264
Plasmodium vivax glutathione reductase, putative 0.1073 0.4902 1
Entamoeba histolytica thioredoxin reductase, putative 0.0186 0.0768 0.2744
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0104 0.0104
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0219 0.0923 0.0943
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1845 0.8497 0.8495
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0422 0.1867 0.1906
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0086 0.0304 0.031
Loa Loa (eye worm) AGC/PKG protein kinase 0.0022 0.0002 0.0003
Treponema pallidum oxidoreductase 0.0186 0.0768 0.2382
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0042 0.0083
Loa Loa (eye worm) hypothetical protein 0.0046 0.0116 0.0231
Trichomonas vaginalis glucosylceramidase, putative 0.0528 0.236 0.5383
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0002 0.0002
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0037 0.0074 0.0073
Echinococcus multilocularis tyrosine protein kinase Srms 0.0072 0.0239 0.0242
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0065 0.0202 0.0205
Brugia malayi jmjC domain containing protein 0.0043 0.0102 0.0185
Loa Loa (eye worm) phosphofructokinase 0.0112 0.0424 0.085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Schistosoma mansoni hypothetical protein 0.0085 0.0299 0.0306
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0114 0.0229
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.006 0.0182 0.0529
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0424 0.0409
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0013 0.0013
Echinococcus multilocularis tyrosine protein kinase Src42A 0.008 0.0275 0.0279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0248 0.054
Brugia malayi larval opioid receptor 0.0219 0.0923 0.1696
Echinococcus granulosus peptide allatostatin:somatostatin 0.0219 0.0923 0.0941
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0046 0.0114 0.0099
Brugia malayi voltage-dependent calcium channel 0.0046 0.0114 0.0206
Leishmania major cytochrome p450-like protein 0.0087 0.0308 0.0306
Loa Loa (eye worm) G-protein coupled receptor 0.0219 0.0923 0.1852
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0029 0.0037 0.0071
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0175 0.035
Trypanosoma cruzi cytochrome P450, putative 0.0087 0.0308 0.0293
Brugia malayi hypothetical protein 0.0219 0.0923 0.1696
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0075 0.0142
Mycobacterium leprae Conserved hypothetical protein 0.006 0.0182 0.0448
Schistosoma mansoni cellular tumor antigen P53 0.0152 0.061 0.0623
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0117 0.0239
Brugia malayi hypothetical protein 0.0219 0.0923 0.1696
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0262 0.0248
Echinococcus multilocularis GPCR, family 2 0.0048 0.0127 0.0128
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0097 0.0174
Brugia malayi Receptor family ligand binding region containing protein 0.0031 0.0046 0.0082
Brugia malayi hypothetical protein 0.0219 0.0923 0.1696
Echinococcus multilocularis nmda type glutamate receptor 0.0109 0.0409 0.0416
Onchocerca volvulus 0.0071 0.0231 0.0494
Echinococcus granulosus neuropeptide Y receptor 0.0219 0.0923 0.0941
Trypanosoma cruzi trypanothione reductase, putative 0.0701 0.3168 0.3158
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0186 0.0768 0.1536
Brugia malayi Dopamine receptor 0.0219 0.0923 0.1696
Echinococcus granulosus nmda type glutamate receptor 0.0199 0.083 0.0846
Brugia malayi Glutamate receptor 2 precursor 0.0174 0.071 0.1304
Echinococcus multilocularis short transient receptor potential channel 6 0.0046 0.0114 0.0114
Brugia malayi Serotonin receptor 0.0219 0.0923 0.1696
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0086 0.0085
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0087 0.0308 0.0922
Entamoeba histolytica ABC transporter, putative 0.0025 0.0016 0.0009
Onchocerca volvulus 0.0219 0.0923 0.2083
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0046 0.0114 0.0116
Loa Loa (eye worm) follicle stimulating hormone receptor 0.068 0.3069 0.6161
Leishmania major hypothetical protein, conserved 0.0046 0.0114 0.0112
Loa Loa (eye worm) doublecortin family protein 0.0082 0.0282 0.0566
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0085 0.0299 0.0548
Loa Loa (eye worm) hypothetical protein 0.0396 0.1746 0.3504
Brugia malayi Protein kinase domain containing protein 0.0053 0.015 0.0272
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0046 0.0117 0.0102
Loa Loa (eye worm) hypothetical protein 0.0038 0.0081 0.0161
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0186 0.0768 0.1564
Echinococcus granulosus 7TM GPCR rhodopsin 0.0219 0.0923 0.0941
Brugia malayi Serotonin receptor 0.1187 0.5432 1
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0637 0.1431
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0186 0.0768 0.0783
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0037 0.0074 0.0059
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.029 0.1252 0.3922
Echinococcus granulosus rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0127 0.0128
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0024 0.0013 0.0023
Plasmodium falciparum thioredoxin reductase 0.1073 0.4902 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0117 0.0239
Schistosoma mansoni hypothetical protein 0.0148 0.0592 0.0605
Brugia malayi Receptor family ligand binding region containing protein 0.0024 0.0015 0.0024
Trypanosoma brucei protein kinase, putative 0.0158 0.0637 0.0622
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0041 0.009 0.0229
Echinococcus multilocularis serotonin receptor 0.0606 0.2725 0.2783
Plasmodium vivax SET domain protein, putative 0.0122 0.047 0.0935
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0841 0.3822 0.7034
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0086 0.0228
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0074 0.0247 0.025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Brugia malayi neuropeptide F receptor 0.0219 0.0923 0.1696
Echinococcus granulosus biogenic amine 5HT receptor 0.0606 0.2725 0.2783
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0138 0.0545 0.053
Brugia malayi Furin-like cysteine rich region family protein 0.0162 0.0657 0.1206
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Echinococcus granulosus 6 phosphofructokinase 0.0112 0.0424 0.0431
Schistosoma mansoni cpg binding protein 0.0064 0.0199 0.0204
Trichomonas vaginalis glucosylceramidase, putative 0.0365 0.1601 0.3643
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0116 0.0443 0.0451
Echinococcus multilocularis NMDA receptor 0.0074 0.0247 0.025
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.0175
Schistosoma mansoni hypothetical protein 0.0685 0.3095 0.3163
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.006 0.0182 0.0336
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0046 0.0114 0.0116
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0018 0.0008
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0186 0.0768 0.0783
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0013 0.0023
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Echinococcus granulosus transient receptor potential cation channel 0.0046 0.0114 0.0114
Chlamydia trachomatis DNA gyrase subunit A 0.0032 0.0051 0.0106
Schistosoma mansoni voltage-gated cation channel 0.0146 0.0582 0.0594
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0086 0.0304 0.0308
Echinococcus multilocularis two pore calcium channel protein 2 0.0046 0.0114 0.0114
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1629 0.7491 0.7488
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0086 0.0167
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.006 0.0182 0.0167
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Echinococcus multilocularis transient receptor potential cation channel 0.0046 0.0114 0.0114
Echinococcus multilocularis tyrosine protein kinase Fyn 0.008 0.0275 0.0279
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0053 0.015 0.0151
Schistosoma mansoni hypothetical protein 0.0048 0.0127 0.013
Onchocerca volvulus 0.0219 0.0923 0.2083
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0065 0.0202 0.0207
Loa Loa (eye worm) hypothetical protein 0.0085 0.0298 0.0597
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0138 0.0545 0.0557
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0046 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0101 0.0374 0.0749
Entamoeba histolytica protein kinase, putative 0.0064 0.0202 0.0685
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0186 0.0768 0.2046
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0057 0.0166 0.0346
Echinococcus granulosus voltage dependent calcium channel 0.0065 0.0202 0.0205
Echinococcus multilocularis 6 phosphofructokinase 0.0112 0.0424 0.0431
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.0185
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0037 0.0074 0.0058
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0093 0.0205
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0008
Schistosoma mansoni transient receptor potential channel 0.0046 0.0114 0.0116
Leishmania major C-8 sterol isomerase-like protein 0.0775 0.3511 0.3509
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0086 0.0304 0.0555
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.006 0.0182 0.0529
Echinococcus multilocularis epidermal growth factor receptor 0.0162 0.0657 0.0669
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0046
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0219 0.0923 0.0941
Echinococcus multilocularis ATP binding cassette sub family G 0.0025 0.0016 0.0014
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0138 0.0545 0.0531
Trichomonas vaginalis set domain proteins, putative 0.0959 0.4372 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0097 0.0193
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0037 0.0073 0.0058
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.0824 0.084
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0067
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0086 0.0304 0.031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0029
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0086 0.0304 0.0308
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0042 0.0097 0.0193
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Echinococcus granulosus g protein coupled receptor 0.0219 0.0923 0.0941
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0047 0.0069
Schistosoma mansoni bromodomain containing protein 0.0069 0.0221 0.0226
Echinococcus granulosus FTZ F1 alpha 0.0042 0.0097 0.0097
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.006 0.0182 0.0336
Echinococcus multilocularis fmrfamide receptor 0.0219 0.0923 0.0941
Echinococcus granulosus glutamate receptor subunit protein glur 0.0074 0.0247 0.025
Echinococcus granulosus voltage gated hydrogen channel 1 0.0046 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0117 0.0447 0.0896
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0148 0.0592 0.1087
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Echinococcus granulosus tm gpcr rhodopsin 0.0774 0.3508 0.3583
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0024 0.0015 0.0029
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0164 0.0665 0.2061
Loa Loa (eye worm) TK protein kinase 0.0064 0.0202 0.0404
Toxoplasma gondii ferodoxin FD 0.0028 0.003 0.0057
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0037 0.0073 0.0072
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0024 0.0013 0.0011
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0086 0.0304 0.0609
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0114 0.0116
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0186 0.0768 0.0783
Echinococcus granulosus transient receptor potential cation channel 0.0046 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0086 0.0304 0.0609
Echinococcus granulosus tyrosine protein kinase Fyn 0.008 0.0275 0.0279
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0085 0.0299 0.0306
Schistosoma mansoni biogenic amine (5HT) receptor 0.1392 0.6386 0.6525
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0186 0.0768 0.1564
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0064 0.0063
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0075 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0117 0.0239
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0067
Loa Loa (eye worm) hypothetical protein 0.0153 0.0614 0.1232
Schistosoma mansoni chromobox protein 0.0024 0.0013 0.0013
Schistosoma mansoni inositol monophosphatase 0.004 0.0086 0.0088
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0025 0.0016 0.0014
Echinococcus multilocularis FTZ F1 alpha 0.0042 0.0097 0.0097
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0037 0.0074 0.0139
Trichomonas vaginalis apoptosis inducing factor, putative 0.0186 0.0768 0.1733
Loa Loa (eye worm) hypothetical protein 0.0042 0.0097 0.0193
Echinococcus multilocularis potassium voltage gated channel protein 0.0046 0.0114 0.0114
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0158 0.0637 0.0635
Schistosoma mansoni amine GPCR 0.0219 0.0923 0.0943
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.006 0.0182 0.0529
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0775 0.3511 0.3501
Schistosoma mansoni inositol monophosphatase 0.004 0.0086 0.0088
Schistosoma mansoni neuropeptide F-like receptor 0.0219 0.0923 0.0943
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0028 0.003 0.0014
Echinococcus granulosus transcription factor Dp 1 0.0078 0.0265 0.0269
Trichomonas vaginalis calmodulin, putative 0.0026 0.0024 0.0024
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0615 0.2766 1
Schistosoma mansoni apoptosis regulator bax 0.0085 0.0299 0.0306
Mycobacterium ulcerans hypothetical protein 0.0041 0.0093 0.0246
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0114 0.0116
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Giardia lamblia [2Fe-2S] ferredoxin 0.0028 0.003 0.0051
Trichomonas vaginalis glutamate synthase, putative 0.0186 0.0768 0.1733
Loa Loa (eye worm) glutathione reductase 0.1073 0.4902 0.9841
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0086 0.0264
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.014 0.0552 0.0564
Brugia malayi Intermediate filament tail domain containing protein 0.0083 0.0288 0.0526
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0186 0.0768 0.2744
Schistosoma mansoni growth hormone secretagogue receptor 0.0219 0.0923 0.0943
Loa Loa (eye worm) TOPoisomerase family member 0.015 0.0599 0.1203
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0186 0.0768 0.0754
Brugia malayi hypothetical protein 0.0219 0.0923 0.1696
Schistosoma mansoni lamin 0.0083 0.0288 0.0294
Echinococcus granulosus Adrenodoxin mitochondrial 0.0028 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0042 0.0097 0.0193
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0146 0.0582 0.0593
Loa Loa (eye worm) hypothetical protein 0.0061 0.0185 0.0371
Plasmodium falciparum thioredoxin reductase 0.0701 0.3168 0.6461
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.1073 0.4902 1
Toxoplasma gondii cytochrome p450 superfamily protein 0.006 0.0182 0.0368
Toxoplasma gondii Erv1 / Alr family protein 0.0037 0.0073 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0069 0.0127
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0106 0.0394 0.0379
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0186 0.0768 0.2388
Plasmodium falciparum phd finger protein, putative 0.0031 0.0047 0.0092
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0158 0.064 0.0652
Echinococcus multilocularis tyrosine protein kinase Fyn 0.008 0.0275 0.0279
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0186 0.0768 0.1733
Brugia malayi isocitrate dehydrogenase 0.0064 0.0199 0.0362
Loa Loa (eye worm) TK protein kinase 0.0072 0.0239 0.0478
Loa Loa (eye worm) hypothetical protein 0.0137 0.0538 0.1079
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0701 0.3168 0.3236
Echinococcus multilocularis chromobox protein 1 0.0086 0.0304 0.0309
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0156 0.0626 0.0638
Brugia malayi neuropeptide F receptor 0.0219 0.0923 0.1696
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0037 0.0074 0.0139
Leishmania major trypanothione reductase 0.1073 0.4902 0.4901
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0138 0.0545 0.1933
Brugia malayi 6-phosphofructokinase 0.0112 0.0424 0.0777
Brugia malayi steroid hormone receptor 0.0042 0.0097 0.0174
Trichomonas vaginalis Ferredoxin 4 0.0028 0.003 0.0039
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Echinococcus multilocularis conserved hypothetical protein 0.1452 0.6665 0.681
Onchocerca volvulus 0.0084 0.029 0.0632
Schistosoma mansoni metabotropic glutamate receptor 0.0024 0.0015 0.0015
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0032 0.0051 0.0106
Schistosoma mansoni metabotropic glutamate receptor 0.0024 0.0015 0.0015
Echinococcus granulosus tyrosine protein kinase Src64B 0.008 0.0275 0.0279
Brugia malayi MH2 domain containing protein 0.0244 0.1038 0.1907
Onchocerca volvulus 0.0089 0.0317 0.0692
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0047 0.0092
Loa Loa (eye worm) hypothetical protein 0.109 0.4982 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Brugia malayi Glutamate receptor 1 precursor 0.0174 0.071 0.1304
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0097 0.0174
Leishmania major NADH dehydrogenase, putative 0.0186 0.0768 0.0767
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0086 0.0086
Echinococcus multilocularis thioredoxin glutathione reductase 0.1073 0.4902 0.5008
Schistosoma mansoni transient receptor potential channel 0.0046 0.0114 0.0116
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0112 0.0424 0.0831
Echinococcus granulosus 7tm_1 domain containing protein 0.0219 0.0923 0.0941
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.006 0.0182 0.0336
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.007 0.0226 0.0211
Onchocerca volvulus Neuropeptide F receptor homolog 0.0219 0.0923 0.2083
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0086 0.0222
Leishmania major hypothetical protein, conserved 0.0028 0.003 0.0028
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0424 0.0942
Echinococcus granulosus CalModulin family member cmd 1 0.0026 0.0024 0.0022
Echinococcus multilocularis dro:myosuppressin receptor 0.0219 0.0923 0.0941
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Echinococcus multilocularis g protein coupled receptor 0.0219 0.0923 0.0941
Echinococcus granulosus chromobox protein 1 0.0086 0.0304 0.0309
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0042 0.0097 0.0099
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0086 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0248 0.054
Schistosoma mansoni sodium-dependent amino acid transporter 0.0086 0.0304 0.031
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0086 0.0071
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0701 0.3168 0.3158
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0219 0.0923 0.0941
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.038 0.0842
Echinococcus granulosus peregrin 0.0034 0.0058 0.0058
Mycobacterium tuberculosis Probable dehydrogenase 0.0297 0.1285 0.2595
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0127 0.0128
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1392 0.6386 0.6524
Echinococcus granulosus two pore calcium channel protein 2 0.0046 0.0114 0.0114
Giardia lamblia DNA repair protein RAD52 0.0337 0.1474 0.4629
Schistosoma mansoni fkbp-rapamycin associated protein 0.0026 0.0023 0.0024
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0046 0.0114 0.0206
Brugia malayi Steroid receptor seven-up type 2 0.0042 0.0097 0.0174
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0086 0.0138
Schistosoma mansoni cytochrome P450 0.006 0.0182 0.0186
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0042 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0727 0.3289 0.6602
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0041 0.009 0.0229
Echinococcus granulosus tyrosine kinase 0.0028 0.003 0.0028
Echinococcus multilocularis serotonin transporter 0.0509 0.2271 0.2319
Echinococcus granulosus tyrosine protein kinase Lyn 0.0083 0.0287 0.0291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0138 0.0545 0.122
Echinococcus granulosus voltage gated potassium channel 0.0046 0.0114 0.0114
Echinococcus granulosus rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Schistosoma mansoni disulfide oxidoreductase 0.0186 0.0768 0.0785
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0262 0.0531
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0117 0.0239
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0086 0.0171
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0102 0.0378 0.0385
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.006 0.0182 0.0336
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.006 0.0182 0.0336
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0114 0.0229
Echinococcus granulosus zinc finger protein 0.0024 0.0011 0.0009
Echinococcus granulosus neuropeptides capa receptor 0.0219 0.0923 0.0941
Echinococcus granulosus alpha 1A adrenergic receptor 0.0219 0.0923 0.0941
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0701 0.3168 0.3167
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0122 0.047 0.0478
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0037 0.0074 0.0072
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0158 0.064 0.1174
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.006 0.0182 0.0336
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0186 0.0768 0.1733
Loa Loa (eye worm) hypothetical protein 0.0146 0.0582 0.1167
Loa Loa (eye worm) hypothetical protein 0.0086 0.0304 0.0609
Echinococcus granulosus tyrosine protein kinase Blk 0.0072 0.0239 0.0242
Echinococcus granulosus tyrosine kinase 0.0072 0.0239 0.0242
Trichomonas vaginalis Ferredoxin 1 0.0028 0.003 0.0039
Loa Loa (eye worm) hypothetical protein 0.0606 0.2725 0.547
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0023 0.0023
Echinococcus multilocularis transient receptor potential gamma protein 0.0046 0.0114 0.0114
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0042 0.006
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0042 0.0097 0.0187
Trypanosoma brucei calmodulin 0.0026 0.0024 0.0008
Toxoplasma gondii histone lysine methyltransferase SET1 0.0118 0.0451 0.0917
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0186 0.0768 0.0754
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0637 0.1431
Leishmania major DNA topoisomerase ii 0.0142 0.0562 0.056
Plasmodium falciparum calmodulin 0.0026 0.0024 0.0044
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0204 0.0206
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0028 0.003 0.0024
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0204 0.0206
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0023 0.0043
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0086 0.0304 0.0609
Echinococcus granulosus receptor type guanylyl cyclase 0.0031 0.0046 0.0045
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.006 0.0182 0.0529
Echinococcus multilocularis two pore calcium channel protein 1 0.0046 0.0114 0.0114
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0046 0.0114 0.0116
Schistosoma mansoni sulfide quinone reductase 0.0186 0.0768 0.0785
Entamoeba histolytica protein kinase rad3, putative 0.0026 0.0023 0.0036
Plasmodium falciparum LCCL domain-containing protein 0.0082 0.0282 0.0572
Mycobacterium tuberculosis Possible oxygenase 0.0028 0.003 0.0024
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0069 0.0174
Echinococcus granulosus rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Echinococcus multilocularis geminin 0.0685 0.3095 0.3161
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0112 0.0424 0.1106
Leishmania major cytochrome p450-like protein 0.006 0.0182 0.018
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0069 0.007
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0046 0.0117 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.038 0.0842
Trichomonas vaginalis glucosylceramidase, putative 0.0528 0.236 0.5383
Echinococcus multilocularis potassium voltage gated channel protein 0.0046 0.0114 0.0114
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0025 0.0026
Echinococcus multilocularis tyrosine protein kinase Fgr 0.008 0.0275 0.0279
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.006 0.0182 0.0529
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0018 0.0033
Loa Loa (eye worm) heterochromatin protein 1 0.0086 0.0304 0.061
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0067
Echinococcus multilocularis 0.0049 0.0132 0.0133
Brugia malayi photoreceptor-specific nuclear receptor 0.0042 0.0097 0.0174
Schistosoma mansoni two-pore calcium channel 0.0046 0.0114 0.0116
Brugia malayi Blistered cuticle protein 3 0.0148 0.0593 0.1088
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0219 0.0923 0.0943
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0086 0.0304 0.031
Loa Loa (eye worm) hypothetical protein 0.0086 0.0304 0.0609
Brugia malayi hypothetical protein 0.0082 0.0282 0.0516
Loa Loa (eye worm) hypothetical protein 0.0088 0.0309 0.062
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0509 0.2271 0.4179
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0042 0.0067
Entamoeba histolytica disulphide oxidoreductase, putative 0.0186 0.0768 0.2744
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0186 0.0768 0.0754
Echinococcus multilocularis tumor protein p63 0.1039 0.4742 0.4844
Brugia malayi DNA topoisomerase II, alpha isozyme 0.015 0.0599 0.11
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.014 0.0552 0.0564
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0042 0.0097 0.0174
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.006 0.0182 0.0529
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0219 0.0923 0.0943
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0701 0.3168 0.3236
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0186 0.0768 0.2388
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0198 0.0824 0.084
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0074 0.0247 0.025
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0086 0.0171
Loa Loa (eye worm) hypothetical protein 0.0048 0.0127 0.0254
Brugia malayi MAP kinase sur-1 0.0158 0.0637 0.1169
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Onchocerca volvulus 0.0219 0.0923 0.2083
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0028 0.003 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.038 0.0842
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0085 0.0299 0.0304
Echinococcus granulosus glutamate receptor 2 0.0198 0.0824 0.084
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0013 0.0013
Schistosoma mansoni loxhd1 0.0082 0.0282 0.0288
Echinococcus granulosus dnaJ subfamily B 0.0836 0.3795 0.3876
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0069 0.007
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0074 0.0247 0.025
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0059
Onchocerca volvulus 0.0028 0.003 0.0034
Echinococcus multilocularis transient receptor potential cation channel 0.0046 0.0116 0.0116
Plasmodium falciparum DNA gyrase subunit A 0.0032 0.0051 0.0101
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0046 0.0114 0.0116
Brugia malayi Inositol-1 0.004 0.0086 0.0154
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0843 0.383 0.7689
Schistosoma mansoni tyrosine kinase 0.0028 0.003 0.003
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.006 0.0182 0.0529
Echinococcus multilocularis chromobox protein 1 0.0086 0.0304 0.0309
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0186 0.0768 0.0783
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0413 0.0918
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0037 0.0073 0.0058
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0086 0.0304 0.0555
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0086 0.0223
Loa Loa (eye worm) hypothetical protein 0.0079 0.0268 0.0538
Echinococcus multilocularis L aminoadipate semialdehyde 0.0089 0.0317 0.0322
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0135 0.053 0.0528
Giardia lamblia NADH oxidase lateral transfer candidate 0.0701 0.3168 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0118 0.0451 0.1005
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0186 0.0768 0.2388
Loa Loa (eye worm) ryanodine receptor 0.0046 0.0114 0.0228
Trichomonas vaginalis glucosylceramidase, putative 0.0528 0.236 0.5383
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0859 0.3902 0.8922
Leishmania major phosphatidylinositol 3-kinase, putative 0.0046 0.0117 0.0115
Entamoeba histolytica DNA topoisomerase II, putative 0.015 0.0599 0.213
Treponema pallidum hypothetical protein 0.0115 0.0437 0.133
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0024 0.0015 0.0029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0075 0.0142
Echinococcus granulosus transient receptor potential cation channel 0.0046 0.0114 0.0114
Brugia malayi sulfakinin receptor protein 0.0219 0.0923 0.1696
Plasmodium vivax DNA topoisomerase II, putative 0.015 0.0599 0.1199
Schistosoma mansoni rac gtpase activating protein 0.0071 0.0232 0.0237
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0424 0.0942
Loa Loa (eye worm) hypothetical protein 0.0061 0.0185 0.0371
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.015 0.0599 0.11
Loa Loa (eye worm) inositol-1 0.004 0.0086 0.0171
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0198 0.0824 0.084
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0024 0.0015 0.0024
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0138 0.0545 0.053
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.0185
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0042 0.0097 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0097 0.0174
Trypanosoma cruzi calmodulin, putative 0.0026 0.0024 0.0008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0008
Brugia malayi Probable DNA topoisomerase II 0.015 0.0599 0.11
Leishmania major mitochondrial DNA topoisomerase II 0.0168 0.0685 0.0683
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0219 0.0923 0.0943
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0046 0.0114 0.0099
Echinococcus granulosus serotonin transporter 0.0509 0.2271 0.2319
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0086 0.0084
Brugia malayi hypothetical protein 0.0219 0.0923 0.1696
Echinococcus multilocularis glutamate receptor 2 0.0124 0.0478 0.0487
Toxoplasma gondii thioredoxin reductase 0.1073 0.4902 1
Schistosoma mansoni lipoxygenase 0.0275 0.1181 0.1207
Schistosoma mansoni hypothetical protein 0.0219 0.0923 0.0943
Echinococcus granulosus lipoxygenase domain containing protein 0.0082 0.0282 0.0286
Loa Loa (eye worm) norepinephrine transporter 0.0509 0.2271 0.4559
Plasmodium vivax thioredoxin reductase, putative 0.1073 0.4902 1
Echinococcus granulosus atrial natriuretic peptide receptor 0.0024 0.0015 0.0013
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0064 0.0199 0.0402
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0046 0.0114 0.0114
Loa Loa (eye worm) CHromoDomain protein family member 0.0029 0.0038 0.0075
Echinococcus granulosus mitogen activated protein kinase 3 0.0158 0.0637 0.0649
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0069 0.0067
Mycobacterium ulcerans electron transfer protein 0.0028 0.003 0.0045
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0186 0.0768 0.1564
Schistosoma mansoni jumonji domain containing protein 0.0081 0.028 0.0286
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0413 0.0918
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0097 0.0099
Echinococcus granulosus glutamate receptor NMDA 0.0085 0.0295 0.03
Echinococcus multilocularis neuropeptide receptor A26 0.1159 0.5302 0.5417
Brugia malayi hypothetical protein 0.0022 0.0004 0.0005
Brugia malayi Heterochromatin protein 1 0.0086 0.0304 0.0556
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0097 0.0174
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0046 0.0114 0.0206
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0615 0.2766 1
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0024 0.0015 0.0029
Echinococcus granulosus serotonin receptor 0.0219 0.0923 0.0941
Schistosoma mansoni hypothetical protein 0.0836 0.3795 0.3877
Brugia malayi glutathione reductase 0.1073 0.4902 0.9023
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.008 0.0275 0.0279
Mycobacterium ulcerans oxidoreductase 0.0028 0.003 0.0045
Echinococcus multilocularis potassium voltage gated channel protein 0.0046 0.0114 0.0114
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0859 0.3902 0.8922
Onchocerca volvulus 0.0219 0.0923 0.2083
Onchocerca volvulus 0.0146 0.0582 0.13
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0701 0.3168 0.3237
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0138 0.0545 0.0543
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0028 0.003 0.0028
Echinococcus granulosus short transient receptor potential channel 6 0.0046 0.0116 0.0116
Loa Loa (eye worm) melatonin receptor type 1A 0.0219 0.0923 0.1852
Mycobacterium ulcerans glutamate synthase subunit beta 0.0186 0.0768 0.2388
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.011 0.0414 0.0412
Echinococcus multilocularis sodium leak channel non selective protein 0.0046 0.0114 0.0114
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0701 0.3168 1
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Loa Loa (eye worm) solute carrier family 6 member 4 0.0509 0.2271 0.4559
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0186 0.0768 0.1411
Echinococcus multilocularis receptor type guanylyl cyclase 0.0031 0.0046 0.0045
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1845 0.8497 0.8495
Trichomonas vaginalis Ferredoxin 6 0.0028 0.003 0.0039
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0219 0.0923 0.0943
Trichomonas vaginalis PIKK family atypical protein kinase 0.0138 0.0545 0.122
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0186 0.0768 0.0783
Leishmania major calmodulin, putative 0.0026 0.0024 0.0022
Echinococcus multilocularis sodium channel protein 0.0505 0.2257 0.2304
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0037 0.0074 0.0073
Echinococcus granulosus hypothetical protein 0.0046 0.0114 0.0114
Schistosoma mansoni hypothetical protein 0.0105 0.0389 0.0397
Echinococcus multilocularis g-protein coupled receptor 0.0219 0.0923 0.0941
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0201 0.0839 0.189
Echinococcus granulosus ATP binding cassette sub family G 0.0025 0.0016 0.0014
Schistosoma mansoni 60S ribosomal protein L21 0.0056 0.0162 0.0166
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0086 0.0304 0.031
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0042 0.006
Onchocerca volvulus 0.0083 0.0288 0.0625
Loa Loa (eye worm) hypothetical protein 0.0047 0.0122 0.0244
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0065 0.0202 0.0435
Schistosoma mansoni sodium/chloride dependent transporter 0.0086 0.0304 0.031
Echinococcus multilocularis sex peptide receptor 0.0219 0.0923 0.0941
Trichomonas vaginalis chromobox protein, putative 0.0057 0.0166 0.0351
Loa Loa (eye worm) hypothetical protein 0.0101 0.0374 0.0749
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0146 0.0582 0.0593
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0065 0.0206 0.019
Echinococcus granulosus thioredoxin glutathione reductase 0.1073 0.4902 0.5008
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0023 0.0039
Echinococcus multilocularis calmodulin 0.0026 0.0024 0.0022
Schistosoma mansoni ATP-binding cassette transporter 0.0174 0.0712 0.0728
Loa Loa (eye worm) serotonin transporter b 0.0509 0.2271 0.4559
Echinococcus granulosus potassium voltage gated channel protein 0.0046 0.0114 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0039 0.006
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0509 0.2271 0.2321
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0249 0.0541
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0064 0.0199 0.0184
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0046 0.0114 0.0114
Echinococcus granulosus tm gpcr rhodopsin 0.0219 0.0923 0.0941
Loa Loa (eye worm) hypothetical protein 0.0024 0.0013 0.0025
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0108 0.0216
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0219 0.0923 0.0943
Echinococcus granulosus Rac GTPase activating protein 1 0.0071 0.0232 0.0235
Loa Loa (eye worm) hypothetical protein 0.0086 0.0304 0.0609
Loa Loa (eye worm) helicase 0.0024 0.0013 0.0025
Echinococcus granulosus chromobox protein 2 0.0024 0.0013 0.0011
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0069 0.0054
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Loa Loa (eye worm) TYRA-2 protein 0.0219 0.0923 0.1852
Trypanosoma cruzi DNA topoisomerase II, putative 0.0142 0.0562 0.0548
Echinococcus granulosus L aminoadipate semialdehyde 0.0089 0.0317 0.0322
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0186 0.0768 0.2388
Loa Loa (eye worm) hypothetical protein 0.0663 0.2991 0.6004
Loa Loa (eye worm) thioredoxin reductase 0.1073 0.4902 0.9841
Echinococcus granulosus transient receptor potential cation channel 0.0046 0.0114 0.0114
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0168 0.0685 0.0671
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0701 0.3168 0.645
Mycobacterium ulcerans hypothetical protein 0.0186 0.0768 0.2388
Plasmodium falciparum DNA gyrase subunit B 0.0087 0.0308 0.0625
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0086 0.0304 0.0308
Loa Loa (eye worm) hypothetical protein 0.0509 0.2271 0.4559
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0069 0.0224 0.0227
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0046 0.0114 0.0114
Echinococcus multilocularis g protein coupled receptor 0.0219 0.0923 0.0941
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0054 0.0151 0.0312
Schistosoma mansoni hypothetical protein 0.0048 0.0127 0.013
Onchocerca volvulus 0.0086 0.0304 0.0662
Toxoplasma gondii hypothetical protein 0.0046 0.0114 0.0229
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0087 0.0308 0.0927
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0046 0.0114 0.0116
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0251 0.0256
Echinococcus granulosus potassium voltage gated channel protein 0.0046 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0065 0.0202 0.0405
Schistosoma mansoni ap endonuclease 0.004 0.0086 0.0087
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1961 0.904 0.9236
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0219 0.0923 0.1696
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0029
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1629 0.7491 0.7487
Schistosoma mansoni tyrosine kinase 0.0085 0.0297 0.0304
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0024 0.0015 0.0013
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0042 0.0067
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0028 0.003 0.0038
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0008
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0505 0.2257 0.2304
Schistosoma mansoni adrenodoxin 0.0028 0.003 0.0031
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0186 0.0768 0.1545
Brugia malayi Guanylyl cyclase protein 23 0.0031 0.0046 0.0082
Loa Loa (eye worm) hypothetical protein 0.0085 0.0298 0.0597
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0158 0.064 0.1283
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0042 0.0097 0.0099
Trypanosoma brucei trypanothione reductase 0.1073 0.4902 0.4894
Echinococcus granulosus somatostatin receptor 0.0219 0.0923 0.0941
Brugia malayi Cyclic-nucleotide gated cation channel 0.0065 0.0202 0.0369
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0037 0.0074 0.0147
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0042 0.0097 0.0193
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0028 0.003 0.0051
Echinococcus granulosus orexin receptor type 2 0.0219 0.0923 0.0941
Brugia malayi N-terminal motif family protein 0.0201 0.0839 0.1541
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.006 0.0182 0.0529
Brugia malayi calmodulin 0.0026 0.0024 0.004
Mycobacterium ulcerans epimerase 0.0041 0.0093 0.0246
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Toxoplasma gondii transporter, cation channel family protein 0.0046 0.0114 0.0229
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0186 0.0768 0.1564
Echinococcus granulosus metabotropic glutamate receptor 5 0.0024 0.0015 0.0013
Loa Loa (eye worm) cytochrome P450 0.006 0.0182 0.0365
Schistosoma mansoni neuropeptide receptor 0.0219 0.0923 0.0943
Trichomonas vaginalis mercuric reductase, putative 0.0701 0.3168 0.7238
Echinococcus multilocularis tyrosine protein kinase Src64B 0.008 0.0275 0.0279
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1845 0.8497 0.8495
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.006 0.0182 0.0529
Echinococcus granulosus tyrosine protein kinase HCK 0.0064 0.0202 0.0204
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0701 0.3168 1
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0138 0.0545 0.0555
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0063 0.0063
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0025 0.0024
Schistosoma mansoni tyrosine kinase 0.0053 0.015 0.0153
Brugia malayi Augmenter of liver regeneration 0.0037 0.0073 0.013
Schistosoma mansoni hypothetical protein 0.005 0.0135 0.0138
Giardia lamblia Thioredoxin reductase 0.0186 0.0768 0.2393
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0093 0.0333 0.0339
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0024 0.0013 0.0011
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0046 0.0114 0.0116
Brugia malayi hypothetical protein 0.0035 0.0064 0.0114
Plasmodium falciparum ferredoxin, putative 0.0028 0.003 0.0057
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0065 0.0202 0.0205
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0025 0.0016 0.0016
Echinococcus granulosus lipoxygenase domain containing protein 0.0082 0.0282 0.0286
Schistosoma mansoni sodium/chloride dependent transporter 0.0509 0.2271 0.2321
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0234 0.0238
Echinococcus granulosus cytochrome P450 2K1 0.006 0.0182 0.0184
Echinococcus multilocularis neuropeptide Y receptor 0.0219 0.0923 0.0941
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0046 0.0114 0.0206
Leishmania major ferredoxin 2fe-2s-like protein 0.0028 0.003 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.006 0.0182 0.0336
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0086 0.0215
Schistosoma mansoni tyrosine kinase 0.0085 0.0297 0.0304
Brugia malayi ecdysteroid receptor 0.0042 0.0097 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0117 0.0239
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0008
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0142 0.0562 0.0547
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0093 0.0333 0.0341
Loa Loa (eye worm) hypothetical protein 0.0105 0.0389 0.0779
Trypanosoma brucei calmodulin 0.0026 0.0024 0.0008
Schistosoma mansoni lamin 0.0083 0.0288 0.0294
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0135 0.053 0.0972
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.006 0.0182 0.0336
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0074 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0346 0.1514 0.3444
Echinococcus granulosus g protein coupled receptor 0.0219 0.0923 0.0941
Echinococcus granulosus transient receptor potential cation channel 0.0046 0.0116 0.0116
Mycobacterium ulcerans oxidoreductase 0.0028 0.003 0.0045
Toxoplasma gondii hypothetical protein 0.0086 0.0304 0.0616
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0042 0.0097 0.0174
Echinococcus multilocularis microtubule associated protein 2 0.2121 0.9787 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0097 0.0194
Brugia malayi hypothetical protein 0.0219 0.0923 0.1696
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0042 0.0097 0.0174
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0186 0.0768 0.1536
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0065 0.0202 0.0205
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0186 0.0768 0.1564
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0186 0.0768 0.0783
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0037 0.0074 0.0221
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0186 0.0768 0.1564
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0219 0.0923 0.0941
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0157 0.0631 0.1671
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0127 0.0128
Schistosoma mansoni tyrosine kinase 0.008 0.0275 0.028
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Echinococcus granulosus epidermal growth factor receptor 0.0162 0.0657 0.0669
Echinococcus multilocularis isocitrate dehydrogenase 0.0064 0.0199 0.0201
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0186 0.0768 0.0783
Trichomonas vaginalis PIKK family atypical protein kinase 0.0083 0.0286 0.0626
Echinococcus multilocularis neuropeptides capa receptor 0.0219 0.0923 0.0941
Echinococcus multilocularis mitogen activated protein kinase 3 0.0158 0.0637 0.0649
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0515 0.2301 0.4234
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0186 0.0768 0.1564
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0088 0.0312 0.0317
Schistosoma mansoni opsin-like receptor 0.0219 0.0923 0.0943
Toxoplasma gondii exonuclease III APE 0.004 0.0086 0.0171
Chlamydia trachomatis DNA gyrase subunit B 0.0087 0.0308 0.0922
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0219 0.0923 0.0941
Loa Loa (eye worm) hypothetical protein 0.0036 0.0069 0.0137
Brugia malayi hypothetical protein 0.0022 0.0004 0.0005
Schistosoma mansoni cpg binding protein 0.0059 0.0175 0.0178
Trichomonas vaginalis glucosylceramidase, putative 0.0346 0.1514 0.3444
Loa Loa (eye worm) hypothetical protein 0.0038 0.0081 0.0161
Leishmania major hypothetical protein, conserved 0.0077 0.0262 0.026
Loa Loa (eye worm) hypothetical protein 0.014 0.0552 0.1107
Echinococcus granulosus neuropeptide receptor 0.0219 0.0923 0.0941
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0146 0.0582 0.0593
Onchocerca volvulus 0.0186 0.0768 0.1728
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0046 0.0117 0.0118
Echinococcus granulosus rhodopsin orphan GPCR 0.0219 0.0923 0.0941
Echinococcus granulosus potassium voltage gated channel protein 0.0046 0.0114 0.0114
Echinococcus granulosus insulin receptor 0.0053 0.015 0.0151
Loa Loa (eye worm) hypothetical protein 0.0071 0.0232 0.0466
Echinococcus multilocularis glutamate receptor 2 0.0198 0.0824 0.084
Plasmodium falciparum amino acid transporter, putative 0.0086 0.0304 0.0616
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0219 0.0923 0.0941
Leishmania major hypothetical protein, conserved 0.0186 0.0768 0.0767
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0186 0.0768 0.1733
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0037 0.0074 0.0147
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0464 0.2065 0.2064
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0039 0.0083 0.0176
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0158 0.064 0.1432
Echinococcus granulosus lamin dm0 0.0083 0.0288 0.0292
Chlamydia trachomatis endonuclease IV 0.0157 0.0631 0.1945
Schistosoma mansoni hypothetical protein 0.0219 0.0923 0.0943
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0701 0.3168 0.6461
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0135 0.053 0.0539
Schistosoma mansoni voltage-gated ion channel 0.0046 0.0114 0.0116
Loa Loa (eye worm) hypothetical protein 0.0029 0.0037 0.0073
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0066 0.0099
Schistosoma mansoni steroid hormone receptor ad4bp 0.0042 0.0097 0.0099
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0042 0.0097 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.038 0.0842
Schistosoma mansoni biogenic amine receptor 0.0219 0.0923 0.0943
Trypanosoma brucei C-8 sterol isomerase, putative 0.0775 0.3511 0.35
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0047 0.0092
Echinococcus granulosus tyrosine protein kinase Fyn 0.008 0.0275 0.0279
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0114 0.0116
Schistosoma mansoni retinoic acid receptor RXR 0.0042 0.0097 0.0099
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0097 0.0097
Echinococcus multilocularis calmodulin 0.0026 0.0023 0.0022
Trichomonas vaginalis Ferredoxin 7 0.0028 0.003 0.0039
Echinococcus multilocularis chromobox protein 2 0.0024 0.0013 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0069 0.0127
Echinococcus granulosus TRP transient receptor potential channel 0.0046 0.0114 0.0114
Echinococcus granulosus two pore calcium channel protein 1 0.0046 0.0114 0.0114
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0164 0.0665 0.1325
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0135 0.053 0.0539
Loa Loa (eye worm) hypothetical protein 0.0024 0.0013 0.0025
Loa Loa (eye worm) hepatopoietin HPO2 0.0037 0.0073 0.0145
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0337 0.1474 0.5307
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.006 0.0182 0.0336
Plasmodium falciparum DNA topoisomerase 2 0.015 0.0599 0.1219
Echinococcus granulosus tumor protein p63 0.1039 0.4742 0.4844
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0841 0.3822 0.3905
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1629 0.7491 0.7488
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0186 0.0768 0.1733
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0923 0.0943
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0046 0.0117 0.0118
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0186 0.0768 0.2046
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0075 0.0142
Mycobacterium ulcerans 6-phosphofructokinase 0.0112 0.0424 0.1295
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0037 0.0074 0.0147
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0069 0.0068
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0158 0.0637 0.1278
Brugia malayi hypothetical protein 0.0071 0.0231 0.0421
Trypanosoma brucei NADH dehydrogenase 0.0186 0.0768 0.0754
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0042 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0042 0.0097 0.0193
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0186 0.0768 0.2744
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0086 0.0304 0.031
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0219 0.0923 0.0941
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0046 0.0114 0.0114
Onchocerca volvulus 0.0152 0.061 0.1364
Schistosoma mansoni glutamate receptor kainate 0.0174 0.071 0.0726
Schistosoma mansoni amine GPCR 0.0219 0.0923 0.0943
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0072 0.0239 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.011 0.0413 0.0918
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0122 0.0471 0.1051
Schistosoma mansoni neuropeptide receptor 0.0219 0.0923 0.0943
Mycobacterium ulcerans hypothetical protein 0.014 0.0552 0.17
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0037 0.0073 0.0072
Loa Loa (eye worm) hypothetical protein 0.0085 0.0299 0.06
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0135 0.053 0.1876
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0042 0.0107
Onchocerca volvulus Glucosylceramidase homolog 0.0346 0.1514 0.3439
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.0013 0.0023
Onchocerca volvulus 0.008 0.0274 0.0594
Loa Loa (eye worm) hypothetical protein 0.0042 0.0097 0.0193
Echinococcus granulosus microtubule associated protein 2 0.2121 0.9787 1
Schistosoma mansoni glutamate synthase 0.0186 0.0768 0.0785
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0158 0.0637 0.0635
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0701 0.3168 0.6461
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.006 0.0182 0.0167
Brugia malayi Tachykinin-like peptides receptor 99D 0.0219 0.0923 0.1696
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0297 0.1285 0.2595
Brugia malayi SRC-1 0.008 0.0275 0.0502
Brugia malayi RE15519p 0.0219 0.0923 0.1696
Echinococcus multilocularis neuropeptide Y receptor 0.0219 0.0923 0.0941
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0186 0.0768 0.2046
Echinococcus granulosus hyperpolarization activated cyclic 0.0065 0.0202 0.0205
Echinococcus multilocularis cpg binding protein 0.0064 0.0199 0.0202
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.03 0.1301 0.4077
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.0073 0.0122
Onchocerca volvulus 0.0219 0.0923 0.2083
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0046 0.0114 0.0206
Schistosoma mansoni tyrosine kinase 0.0085 0.0297 0.0304
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0064 0.0199 0.0201
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0923 0.0943
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0186 0.0768 0.1545
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0023 0.0022
Trichomonas vaginalis chromobox protein, putative 0.0086 0.0304 0.0668
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.006 0.0182 0.0529
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0158 0.064 0.0652
Plasmodium vivax multidomain scavenger receptor, putative 0.0082 0.0282 0.0551
Entamoeba histolytica hypothetical protein 0.0026 0.0023 0.0036
Schistosoma mansoni chromobox protein 0.0086 0.0304 0.0311
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.006 0.0182 0.0336
Echinococcus granulosus calmodulin 0.0026 0.0024 0.0022
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0219 0.0923 0.0943
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0528 0.236 0.4342
Echinococcus granulosus calcium activated potassium channel 0.0048 0.0126 0.0127
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0047 0.0046
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0102 0.0105
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0046 0.0114 0.0114
Echinococcus granulosus sodium and chloride dependent glycine 0.0086 0.0304 0.0308
Echinococcus multilocularis tyrosine kinase 0.0028 0.003 0.0028
Schistosoma mansoni biogenic amine (5HT) receptor 0.0606 0.2725 0.2784
Plasmodium vivax ferredoxin, putative 0.0028 0.003 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0151 0.0317
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0086 0.0071
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0075 0.0251 0.0255
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0046 0.0114 0.0116
Brugia malayi RhoGAP domain containing protein 0.0061 0.0187 0.0341
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0075 0.0251 0.0459
Loa Loa (eye worm) hypothetical protein 0.0089 0.0317 0.0635
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0029
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0004 0.0003
Schistosoma mansoni hypothetical protein 0.0074 0.0247 0.0252
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0075 0.0251 0.0255
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.006 0.0182 0.0336
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0069 0.0068
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.006 0.0182 0.0529
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0158 0.0637 0.0623
Schistosoma mansoni eyes absent homolog 0.0085 0.0298 0.0304
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0151 0.0317
Plasmodium falciparum ABC transporter G family member 2 0.0025 0.0016 0.0028
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0129 0.0502 0.0513
Onchocerca volvulus 0.0033 0.0054 0.009
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.006 0.0182 0.0529
Echinococcus multilocularis conserved hypothetical protein 0.0046 0.0114 0.0114
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0146 0.0582 0.0593
Brugia malayi Bromodomain containing protein 0.0034 0.0058 0.0104
Echinococcus multilocularis zinc finger protein 0.0024 0.0011 0.0009
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0046 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0606 0.2725 0.547
Echinococcus multilocularis ryanodine receptor 44f 0.0046 0.0114 0.0115
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0186 0.0768 0.1733
Chlamydia trachomatis thioredoxin reductase 0.0186 0.0768 0.2382
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0069 0.0068
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0424 0.0942
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0064 0.0199 0.0203
Loa Loa (eye worm) hypothetical protein 0.0042 0.0097 0.0193
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2167 1 1
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.008 0.0275 0.0279
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0046 0.0114 0.0114
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0086 0.0167
Echinococcus multilocularis epidermal growth factor receptor 0.0088 0.0312 0.0317
Echinococcus granulosus geminin 0.0685 0.3095 0.3161
Loa Loa (eye worm) hypothetical protein 0.0152 0.061 0.1223
Echinococcus granulosus g protein coupled receptor 0.0219 0.0923 0.0941
Trichomonas vaginalis glutamate synthase, putative 0.0186 0.0768 0.1733
Loa Loa (eye worm) apoptosis regulator protein 0.0085 0.0299 0.06
Echinococcus multilocularis thyroid hormone receptor alpha 0.0042 0.0097 0.0097
Schistosoma mansoni opsin-like receptor 0.0219 0.0923 0.0943
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0028 0.003 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0923 0.0943
Onchocerca volvulus 0.0026 0.0023 0.0019
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0046 0.0114 0.0114
Loa Loa (eye worm) phosphatidylinositol 3 0.0138 0.0545 0.1093
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Loa Loa (eye worm) transcription factor SMAD2 0.0244 0.1038 0.2082
Schistosoma mansoni lipoxygenase 0.0422 0.1867 0.1907
Mycobacterium ulcerans DNA gyrase subunit B 0.0087 0.0308 0.0929
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0186 0.0768 0.0754
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2167 1 1
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0351 0.1537 0.1569
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0065 0.0202 0.0207
Loa Loa (eye worm) hypothetical protein 0.0022 0.0004 0.0008
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0219 0.0923 0.0941
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0701 0.3168 1
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0424 0.1492
Schistosoma mansoni ryanodine receptor related 0.0046 0.0114 0.0117
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0042 0.0097 0.0099
Schistosoma mansoni neuropeptide F-like receptor 0.0219 0.0923 0.0943
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0046 0.0114 0.0116
Onchocerca volvulus 0.0219 0.0923 0.2083
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0031 0.0047 0.0078
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0004 0.0003
Schistosoma mansoni zinc finger protein 0.0024 0.0011 0.0011
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.009 0.0321 0.0326
Schistosoma mansoni neuropeptide f receptor 76f 0.0219 0.0923 0.0943
Echinococcus granulosus lysine specific demethylase 5A 0.0043 0.0102 0.0103
Loa Loa (eye worm) SRC-1 0.008 0.0275 0.055
Brugia malayi bZIP transcription factor family protein 0.009 0.0321 0.0587
Brugia malayi Valyl-tRNA synthetase 0.0024 0.0013 0.002
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0046 0.0114 0.0114
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0186 0.0768 0.0754
Schistosoma mansoni vesicular amine transporter 0.0046 0.0114 0.0116
Plasmodium vivax calmodulin, putative 0.0026 0.0024 0.0022
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0028 0.003 0.0029
Trichomonas vaginalis glucosylceramidase, putative 0.0346 0.1514 0.3444
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0923 0.0943
Brugia malayi hypothetical protein 0.0077 0.0262 0.048
Echinococcus multilocularis neuropeptide FF receptor 2 0.0219 0.0923 0.0941
Loa Loa (eye worm) voltage-gated potassium channel 0.0046 0.0114 0.0228
Toxoplasma gondii calmodulin, putative 0.0026 0.0024 0.0044
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0122 0.0471 0.1051
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0029
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0041 0.009 0.0229
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0031 0.0047 0.0078
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0024 0.0013 0.002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0046 0.0076
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0219 0.0923 0.1852
Onchocerca volvulus 0.0082 0.0282 0.0613
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0039 0.006
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0186 0.0768 0.1411
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0186 0.0768 0.0783
Schistosoma mansoni glutamate synthase 0.0186 0.0768 0.0785
Echinococcus granulosus transient receptor potential gamma protein 0.0046 0.0114 0.0114
Schistosoma mansoni hypothetical protein 0.0024 0.0013 0.0013
Schistosoma mansoni voltage-gated potassium channel 0.0065 0.0202 0.0207
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0046 0.0114 0.0206
Echinococcus multilocularis neuropeptide receptor 0.0219 0.0923 0.0941
Brugia malayi G protein-coupled receptor 0.0219 0.0923 0.1696
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0186 0.0768 0.2388
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0198 0.0824 0.084
Brugia malayi hypothetical protein 0.005 0.0134 0.0244
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.0637 0.1431
Loa Loa (eye worm) steroid hormone receptor 0.0042 0.0097 0.0193
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0018 0.0033
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.006 0.0182 0.0529
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0029 0.0038 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0138 0.0545 0.122
Schistosoma mansoni hypothetical protein 0.0046 0.0114 0.0116
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0422 0.1867 0.1906
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0042 0.0097 0.0174
Schistosoma mansoni tyrosine kinase 0.0162 0.0657 0.0671
Loa Loa (eye worm) hypothetical protein 0.0084 0.029 0.0582
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0186 0.0768 0.0783
Echinococcus multilocularis calmodulin 0.0026 0.0024 0.0022
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0046 0.0114 0.0114
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0219 0.0923 0.0941
Onchocerca volvulus Bile acid receptor homolog 0.0042 0.0097 0.0187
Echinococcus granulosus potassium large conductance calcium activated 0.0046 0.0114 0.0114
Brugia malayi hypothetical protein 0.0024 0.0015 0.0024
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0569 0.2552 0.8044
Echinococcus granulosus glutamate receptor 2 0.0124 0.0478 0.0487
Echinococcus granulosus DNA topoisomerase 2 alpha 0.015 0.0599 0.0611
Echinococcus multilocularis calmodulin 0.0026 0.0024 0.0022
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0086 0.0086
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0086 0.0304 0.0616
Echinococcus granulosus neuropeptide Y receptor 0.0219 0.0923 0.0941
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.0389 0.0712
Schistosoma mansoni chromobox protein 0.0024 0.0013 0.0013
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0115 0.0436 0.0444
Toxoplasma gondii hypothetical protein 0.0046 0.0114 0.0229
Onchocerca volvulus 0.0219 0.0923 0.2083
Chlamydia trachomatis ferredoxin 0.0028 0.003 0.0038
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0023 0.0024
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0064 0.0199 0.0201
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0135 0.053 0.1062
Loa Loa (eye worm) hypothetical protein 0.0219 0.0923 0.1852
Trichomonas vaginalis chromobox protein, putative 0.0086 0.0304 0.0668
Echinococcus granulosus chromobox protein 1 0.0086 0.0304 0.0309
Brugia malayi 6-phosphofructokinase 0.0113 0.0426 0.078
Trypanosoma cruzi adrenodoxin precursor, putative 0.0028 0.003 0.0015
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0069 0.0068
Echinococcus multilocularis glutamate synthase 0.0186 0.0768 0.0783
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0108 0.0196
Entamoeba histolytica hypothetical protein 0.0024 0.0015 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0082 0.0282 0.0617
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Loa Loa (eye worm) hypothetical protein 0.0046 0.0114 0.0228
Schistosoma mansoni survival motor neuron protein 0.0148 0.0592 0.0605
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.029 0.1252 0.3922
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0046 0.0114 0.0227
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.2766 0.6315
Giardia lamblia GTOR 0.0138 0.0545 0.1685
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.006 0.0182 0.0336
Onchocerca volvulus 0.0219 0.0923 0.2083
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0106 0.0394 0.0379
Echinococcus granulosus neuropeptide s receptor 0.1159 0.5302 0.5417
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0046 0.0076
Schistosoma mansoni voltage-gated potassium channel 0.0166 0.0675 0.069
Echinococcus granulosus tachykinin peptides receptor 99D 0.0219 0.0923 0.0941
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0072 0.0239 0.0242
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0114 0.0116
Echinococcus multilocularis transient receptor potential cation channel 0.0046 0.0114 0.0114
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0097 0.0174
Echinococcus multilocularis fmrfamide receptor 0.0219 0.0923 0.0941
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0093 0.0333 0.0339
Echinococcus granulosus mitogen activated protein kinase 0.0158 0.0637 0.0649
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0186 0.0768 0.2382
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0086 0.0304 0.0308
Echinococcus multilocularis tyrosine protein kinase Fyn 0.008 0.0275 0.0279
Trypanosoma cruzi target of rapamycin kinase 3 0.011 0.0414 0.0399
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0046 0.0114 0.0206
Entamoeba histolytica hypothetical protein 0.0035 0.0064 0.0185
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0186 0.0768 0.1733
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0135 0.053 0.0515
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0097 0.0099
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0041 0.0093 0.0179
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0219 0.0923 0.0943
Loa Loa (eye worm) G-protein coupled receptor 0.0219 0.0923 0.1852
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0219 0.0923 0.1852
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.2766 0.6315
Echinococcus granulosus nmda type glutamate receptor 0.0109 0.0409 0.0416
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0057 0.0169 0.0153
Loa Loa (eye worm) voltage-gated calcium channel 0.0046 0.0114 0.0228
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1629 0.7491 0.7491
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.003 0.0015
Brugia malayi CXXC zinc finger family protein 0.0059 0.0175 0.0318
Loa Loa (eye worm) hypothetical protein 0.0083 0.0288 0.0577
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0042 0.0097 0.0099
Brugia malayi Melatonin receptor type 1A 0.0219 0.0923 0.1696
Echinococcus multilocularis musashi 0.0083 0.0288 0.0292
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0029
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0064 0.0199 0.0201
Brugia malayi olfactory channel protein osm-9 0.0046 0.0116 0.0209
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0262 0.0248
Echinococcus granulosus calmodulin 0.0026 0.0024 0.0022
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0186 0.0768 0.0754
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0026 0.0023 0.0022
Schistosoma mansoni hypothetical protein 0.0219 0.0923 0.0943
Echinococcus granulosus lamin 0.0083 0.0288 0.0292
Echinococcus granulosus GPCR family 2 0.0048 0.0127 0.0128
Schistosoma mansoni alpha-1 adrenergic receptor 0.0219 0.0923 0.0943
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.0637 0.0651
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0158 0.0637 0.0623
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0424 0.0433
Echinococcus granulosus G protein coupled receptor 139 0.0219 0.0923 0.0941
Echinococcus multilocularis transfer RNA-Gly 0.0046 0.0114 0.0114
Echinococcus granulosus Chromo domain 0.0024 0.0013 0.0011
Schistosoma mansoni glutamate receptor kainate 0.0174 0.071 0.0726
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0114 0.0116
Loa Loa (eye worm) CYP4Cod1 0.0087 0.0308 0.0617
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0186 0.0768 0.1733
Echinococcus granulosus voltage gated potassium channel 0.0075 0.0251 0.0255
Brugia malayi Cytochrome P450 family protein 0.0154 0.0619 0.1136
Treponema pallidum hypothetical protein 0.014 0.0552 0.1694
Brugia malayi Adenylyl cyclase protein 0.0084 0.029 0.0531
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0114 0.0116

Activities

Activity type Activity value Assay description Source Reference
CC50 (ADMET) > 100 uM Cytotoxicity against Jurkat cells by Alamar blue assay ChEMBL. 17540562
CC50 (ADMET) > 100 uM Cytotoxicity against Jurkat cells by Alamar blue assay ChEMBL. 17540562
EC50 (functional) = 15.6 uM Inhibition of LPS-induced TNFalpha production in Jurkat cells ChEMBL. 17540562
EC50 (functional) = 15.6 uM Inhibition of LPS-induced TNFalpha production in Jurkat cells ChEMBL. 17540562
IC50 (binding) = 0.13 uM Inhibition of IKKbeta ChEMBL. 17540562
IC50 (binding) = 0.13 uM Inhibition of IKKbeta ChEMBL. 17540562
IC50 (binding) = 4.4 uM Inhibition of IKKalpha ChEMBL. 17540562
IC50 (binding) = 4.4 uM Inhibition of IKKalpha ChEMBL. 17540562

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 17540562

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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