Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | epidermal growth factor receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.1479 | 1 | 0.5 |
Plasmodium falciparum | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.1479 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.0288 | 0.0276 |
Echinococcus granulosus | epidermal growth factor receptor | 0.018 | 0.0873 | 0.0862 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0281 | 0.0269 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0281 | 0.0269 |
Mycobacterium tuberculosis | Conserved hypothetical membrane protein | 0.0646 | 0.4145 | 0.5 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.1479 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.018 | 0.0873 | 0.0862 |
Plasmodium vivax | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.1479 | 1 | 0.5 |
Loa Loa (eye worm) | protein-S isoprenylcysteine O-methyltransferase | 0.1479 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.0288 | 0.0276 |
Leishmania major | prenyl protein specific carboxyl methyltransferase, putative | 0.1479 | 1 | 0.5 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.018 | 0.0873 | 0.0873 |
Trypanosoma brucei | prenyl protein specific carboxyl methyltransferase | 0.1479 | 1 | 0.5 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0097 | 0.0288 | 0.0276 |
Mycobacterium ulcerans | hypothetical protein | 0.0646 | 0.4145 | 0.5 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.1479 | 1 | 0.5 |
Giardia lamblia | Isoprenylcysteine carboxyl methyltransferase | 0.1479 | 1 | 0.5 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.1479 | 1 | 0.5 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.1479 | 1 | 0.5 |
Schistosoma mansoni | protein-s-isoprenylcysteine o-methyltransferase | 0.1479 | 1 | 1 |
Echinococcus multilocularis | 0.1479 | 1 | 1 | |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0097 | 0.0288 | 0.0288 |
Echinococcus granulosus | protein S isoprenylcysteine O methyltransferase | 0.1479 | 1 | 1 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.1479 | 1 | 0.5 |
Toxoplasma gondii | isoprenylcysteine carboxyl methyltransferase (icmt) family protein | 0.1479 | 1 | 0.5 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.1479 | 1 | 0.5 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0058 | 0.0013 | 0.0013 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.018 | 0.0873 | 0.0862 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.018 | 0.0873 | 0.0862 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0097 | 0.0288 | 0.0276 |
Echinococcus multilocularis | insulin receptor | 0.0058 | 0.0013 | 0.0013 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0281 | 0.0269 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.