Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | epidermal growth factor receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | prenyl protein specific carboxyl methyltransferase, putative | 0.3998 | 1 | 0.5 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.018 | 0.0315 | 0.0315 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.0104 | 0.01 |
Loa Loa (eye worm) | protein-S isoprenylcysteine O-methyltransferase | 0.3998 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.1746 | 0.4286 | 0.5 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0097 | 0.0104 | 0.01 |
Trypanosoma brucei | prenyl protein specific carboxyl methyltransferase | 0.3998 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0101 | 0.0097 |
Echinococcus granulosus | epidermal growth factor receptor | 0.018 | 0.0315 | 0.0311 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.0104 | 0.01 |
Plasmodium falciparum | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.3998 | 1 | 0.5 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.3998 | 1 | 0.5 |
Plasmodium vivax | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.3998 | 1 | 0.5 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.3998 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.018 | 0.0315 | 0.0311 |
Mycobacterium tuberculosis | Conserved hypothetical membrane protein | 0.1746 | 0.4286 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0101 | 0.0097 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0097 | 0.0104 | 0.0104 |
Echinococcus granulosus | protein S isoprenylcysteine O methyltransferase | 0.3998 | 1 | 1 |
Echinococcus multilocularis | 0.3998 | 1 | 1 | |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.0101 | 0.0097 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0097 | 0.0104 | 0.01 |
Echinococcus multilocularis | insulin receptor | 0.0058 | 0.0005 | 0.0005 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.3998 | 1 | 0.5 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.018 | 0.0315 | 0.0311 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0058 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.018 | 0.0315 | 0.0311 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.3998 | 1 | 0.5 |
Toxoplasma gondii | isoprenylcysteine carboxyl methyltransferase (icmt) family protein | 0.3998 | 1 | 0.5 |
Giardia lamblia | Isoprenylcysteine carboxyl methyltransferase | 0.3998 | 1 | 0.5 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.3998 | 1 | 0.5 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.3998 | 1 | 0.5 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.3998 | 1 | 0.5 |
Schistosoma mansoni | protein-s-isoprenylcysteine o-methyltransferase | 0.3998 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.