Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | ATP citrate lyase | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target/s | Ortholog Group |
---|---|---|---|
Neospora caninum | cDNA FLJ55447, highly similar to ATP-citrate synthase (EC 2.3.3.8), related | Get druggable targets OG5_129655 | All targets in OG5_129655 |
Schistosoma mansoni | ATP-citrate synthase | Get druggable targets OG5_129655 | All targets in OG5_129655 |
Schistosoma japonicum | ATP-citrate synthase, putative | Get druggable targets OG5_129655 | All targets in OG5_129655 |
Toxoplasma gondii | ATP-citrate lyase, putative | Get druggable targets OG5_129655 | All targets in OG5_129655 |
Schistosoma japonicum | ko:K01648 ATP citrate (pro-S)-lyase [EC2.3.3.8], putative | Get druggable targets OG5_129655 | All targets in OG5_129655 |
Brugia malayi | ATP-citrate synthase | Get druggable targets OG5_129655 | All targets in OG5_129655 |
Schistosoma japonicum | ATP-citrate synthase, putative | Get druggable targets OG5_129655 | All targets in OG5_129655 |
Loa Loa (eye worm) | ATP-citrate synthase | Get druggable targets OG5_129655 | All targets in OG5_129655 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.