Detailed information for compound 46031

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 283.277 | Formula: C13H17NO6
  • H donors: 5 H acceptors: 5 LogP: -0.58 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCC1OC(C(=O)Nc2ccccc2)C(C(C1O)O)O
  • InChi: 1S/C13H17NO6/c15-6-8-9(16)10(17)11(18)12(20-8)13(19)14-7-4-2-1-3-5-7/h1-5,8-12,15-18H,6H2,(H,14,19)
  • InChiKey: ACZBWELNTOVRFG-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0036 0.0055 0.0098
Loa Loa (eye worm) glutaminase 0.0566 0.1245 0.2301
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0016 0.0011
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.001 0.0014
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0029 0.0087
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0076 0.0146 0.0266
Schistosoma mansoni sodium-dependent amino acid transporter 0.0041 0.0067 0.0119
Echinococcus multilocularis fmrfamide receptor 0.0059 0.0107 0.0195
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.0093 0.0167
Onchocerca volvulus 0.0059 0.0107 0.0934
Leishmania major pyruvate kinase 0.0037 0.0058 0.0103
Echinococcus granulosus neuropeptide Y receptor 0.0059 0.0107 0.0195
Onchocerca volvulus 0.0084 0.0164 0.1661
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0013 0.0019
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.0371 0.0808 0.4567
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Schistosoma mansoni phosphoglucomutase 0.0316 0.0685 0.1264
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0059 0.0107 0.0195
Schistosoma mansoni glutaminase 0.0566 0.1245 0.2301
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0018 0.0016 0.0015
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0018 0.0016 0.0014
Schistosoma mansoni intermediate filament proteins 0.003 0.0042 0.0074
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Schistosoma mansoni biogenic amine receptor 0.0059 0.0107 0.0195
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.0533 0.0982
Schistosoma mansoni hypothetical protein 0.0027 0.0035 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0107 0.0195
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Echinococcus granulosus peptide allatostatin:somatostatin 0.0059 0.0107 0.0195
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0018 0.0016 0.0015
Schistosoma mansoni BC026374 protein (S09 family) 0.0205 0.0435 0.0801
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0118 0.0214
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0059 0.0107 0.0195
Brugia malayi hypothetical protein 0.0059 0.0107 0.0199
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0036 0.0062
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.004 0.0069
Echinococcus granulosus g protein coupled receptor 0.0059 0.0107 0.0195
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0032 0.0054
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.001 0.0014
Toxoplasma gondii hypothetical protein 0.0041 0.0067 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Mycobacterium leprae putative cytochrome p450 0.0018 0.0016 0.0202
Mycobacterium leprae conserved hypothetical protein 0.004 0.0065 0.0916
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0127 0.0259 0.1403
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0059 0.0107 0.0195
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0018 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Echinococcus granulosus geminin 0.0356 0.0773 0.1428
Trichomonas vaginalis NeSL-1_NeSL reverse transcriptases, putative 0.0027 0.0035 0.0112
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0029 0.0048
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0011 0.0016
Schistosoma mansoni phosphoglucomutase 0.0316 0.0685 0.1264
Mycobacterium tuberculosis Conserved protein 0.004 0.0065 0.0067
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0067 0.0105
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0022 0.0036
Loa Loa (eye worm) hypothetical protein 0.0205 0.0435 0.08
Echinococcus granulosus Protein patched homolog 1 0.0042 0.007 0.0126
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0067 0.0105
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0059 0.0107 0.0195
Plasmodium falciparum glutathione reductase 0.0018 0.0016 0.0025
Onchocerca volvulus 0.0059 0.0107 0.0934
Plasmodium falciparum protoporphyrinogen oxidase 0.0315 0.0681 0.1256
Toxoplasma gondii ABC1 family protein 0.004 0.0065 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Trichomonas vaginalis spcc417.12 protein, putative 0.0205 0.0435 0.2414
Leishmania major importin beta-1 subunit, putative 0.0025 0.0032 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Echinococcus multilocularis Bromodomain containing protein 0.0371 0.0808 0.1492
Onchocerca volvulus Brd8 homolog 0.0084 0.0164 0.1661
Trichomonas vaginalis bromodomain-containing protein, putative 0.0791 0.1751 1
Trichomonas vaginalis bromodomain containing protein, putative 0.0084 0.0164 0.0852
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Schistosoma mansoni biogenic amine receptor 0.0059 0.0107 0.0195
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0058 0.0294
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.0016 0.0025
Brugia malayi hypothetical protein 0.0059 0.0107 0.0199
Echinococcus multilocularis expressed conserved protein 0.0093 0.0183 0.0335
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0041 0.0067 0.0119
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0084 0.0164 0.0852
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0059 0.0107 0.0195
Echinococcus granulosus protein kinase C binding protein 1 0.0084 0.0164 0.0299
Echinococcus multilocularis neuropeptide receptor A26 0.0514 0.1129 0.2086
Schistosoma mansoni inositol monophosphatase 0.004 0.0064 0.0115
Giardia lamblia Hypothetical protein 0.0084 0.0164 0.1867
Plasmodium vivax bromodomain protein, putative 0.0084 0.0164 0.0299
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.0075 0.0344
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0022 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0018 0.0016 0.0015
Echinococcus multilocularis bloom syndrome protein 0.0045 0.0075 0.0135
Echinococcus multilocularis pyruvate kinase 0.0029 0.004 0.0071
Schistosoma mansoni CREB-binding protein 2 0.0084 0.0164 0.0299
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0065 0.0119
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0107 0.0195
Echinococcus multilocularis G-protein coupled receptor, putative 0.0059 0.0107 0.0195
Trichomonas vaginalis ran, putative 0.0023 0.0026 0.0061
Brugia malayi Bromodomain containing protein 0.0791 0.1751 0.3241
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0039 0.0067
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0018 0.0016 0.0014
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0315 0.0681 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0076 0.0146 0.0266
Mycobacterium tuberculosis Possible oxidoreductase 0.0315 0.0681 0.073
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0018 0.0016 0.0015
Brugia malayi reverse transcriptase 0.0027 0.0035 0.0065
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0127 0.0259 0.0463
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0058 0.0103
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0043 0.0075
Loa Loa (eye worm) carboxylesterase 0.0205 0.0435 0.08
Brugia malayi Amidase family protein 0.0012 0.0002 0.0004
Leishmania major hypothetical protein, conserved 0.0084 0.0164 0.0299
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0067 0.0123
Onchocerca volvulus 0.0059 0.0107 0.0934
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0146 0.0266
Trypanosoma brucei ingi protein (ORF1) 0.0343 0.0745 0.1376
Plasmodium falciparum bromodomain protein, putative 0.0084 0.0164 0.0299
Echinococcus granulosus 7TM GPCR rhodopsin 0.0059 0.0107 0.0195
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0018 0.0016 0.0014
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.0791 0.1751 0.3238
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.007 0.0313
Brugia malayi hypothetical protein 0.0315 0.0681 0.126
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0042 0.0073
Echinococcus granulosus tar DNA binding protein 0.0064 0.0118 0.0214
Giardia lamblia Kinase, putative 0.0371 0.0808 1
Onchocerca volvulus 0.0059 0.0107 0.0934
Onchocerca volvulus Bromodomain adjacent to zinc finger domain protein 1A homolog 0.0084 0.0164 0.1661
Toxoplasma gondii bromodomain-containing protein 0.0084 0.0164 0.0285
Plasmodium vivax JmjC domain containing protein 0.0016 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Trypanosoma brucei RNA helicase, putative 0.1187 0.2638 0.4881
Loa Loa (eye worm) carboxylesterase 0.0205 0.0435 0.08
Entamoeba histolytica tartrate dehydrogenase, putative 0.0294 0.0634 0.7787
Leishmania major UDP-galactopyranose mutase 0.0315 0.0681 0.1256
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0255 0.0548 0.0587
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0064 0.0543
Brugia malayi SWIRM domain containing protein 0.0315 0.0681 0.126
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0883 0.1958 0.3621
Brugia malayi sulfakinin receptor protein 0.0059 0.0107 0.0199
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.001 0.0014
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0035 0.0065
Loa Loa (eye worm) cytochrome P450 family protein 0.004 0.0064 0.0113
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0041 0.0067 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1212 0.2696 0.4988
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.0093 0.0167
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0343 0.0745 0.1376
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0016 0.0025
Mycobacterium tuberculosis Probable oxidoreductase 0.0133 0.0274 0.0292
Echinococcus multilocularis neuropeptide s receptor 0.0514 0.1129 0.2086
Brugia malayi glutaminase DH11.1 0.0566 0.1245 0.2304
Echinococcus granulosus PH interacting protein 0.0084 0.0164 0.0299
Brugia malayi jmjC domain containing protein 0.0016 0.001 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.0808 0.4567
Echinococcus granulosus sex peptide receptor 0.0059 0.0107 0.0195
Echinococcus multilocularis acetylcholinesterase 0.1212 0.2696 0.4988
Onchocerca volvulus 0.004 0.0065 0.038
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0018 0.0016 0.0013
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0102 0.0203 0.0372
Echinococcus granulosus orexin receptor type 2 0.0059 0.0107 0.0195
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0085 0.0165 0.086
Echinococcus multilocularis 0.0084 0.0164 0.0299
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Echinococcus granulosus phd:f box containing protein 0.0016 0.001 0.0014
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.2418 0.5403 1
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0315 0.0681 0.1256
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Echinococcus granulosus neuropeptides capa receptor 0.0059 0.0107 0.0195
Brugia malayi Pre-SET motif family protein 0.0207 0.0438 0.0812
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0076 0.0146 0.0266
Echinococcus multilocularis neuropeptide Y receptor 0.0059 0.0107 0.0195
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0018 0.0016 0.0026
Schistosoma mansoni amine oxidase 0.0315 0.0681 0.1257
Plasmodium vivax amine transporter, putative 0.0041 0.0067 0.0119
Brugia malayi hypothetical protein 0.0027 0.0035 0.0065
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0115 0.0208
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0018 0.0016 0.0026
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0016 0.0025
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.2418 0.5403 1
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0064 0.0062
Toxoplasma gondii hypothetical protein 0.0041 0.0067 0.0105
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0041 0.0067 0.0119
Brugia malayi MH1 domain containing protein 0.0017 0.0013 0.0024
Loa Loa (eye worm) hypothetical protein 0.0084 0.0164 0.0299
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.001 0.0014
Brugia malayi G-protein coupled receptor 0.0059 0.0107 0.0199
Schistosoma mansoni amine GPCR 0.0059 0.0107 0.0195
Entamoeba histolytica pyruvate kinase, putative 0.0026 0.0033 0.0141
Brugia malayi ATPase, AAA family protein 0.0419 0.0915 0.1694
Echinococcus granulosus survival motor neuron protein 1 0.023 0.0491 0.0905
Brugia malayi Carboxylesterase family protein 0.0205 0.0435 0.0804
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0058 0.0103
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0041 0.0067 0.0119
Leishmania major ATPase, putative 0.0335 0.0727 0.1341
Brugia malayi hypothetical protein 0.0018 0.0014 0.0027
Schistosoma mansoni amidase 0.0102 0.0203 0.0372
Echinococcus multilocularis peregrin 0.0084 0.0164 0.0299
Brugia malayi Bromodomain containing protein 0.0791 0.1751 0.3241
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0624 0.3505
Loa Loa (eye worm) hypothetical protein 0.023 0.0491 0.0904
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0065 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Schistosoma mansoni neuropeptide receptor 0.0059 0.0107 0.0195
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0065 0.0067
Echinococcus granulosus g protein coupled receptor 0.0059 0.0107 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Trypanosoma brucei Endonuclease-reverse transcriptase/Reverse transcriptase (RNA-dependent DNA polymerase), putative 0.0027 0.0035 0.0061
Schistosoma mansoni hypothetical protein 0.0059 0.0107 0.0195
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0035 0.0061
Loa Loa (eye worm) acetylcholinesterase 1 0.1212 0.2696 0.4988
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0059 0.0107 0.0195
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0146 0.0266
Loa Loa (eye worm) hypothetical protein 0.0084 0.0164 0.0299
Brugia malayi Pre-SET motif family protein 0.003 0.0043 0.0079
Brugia malayi GnHR receptor homolog 0.0059 0.0107 0.0199
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0065 0.0067
Brugia malayi hypothetical protein 0.0027 0.0035 0.0065
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0018 0.0016 0.0014
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0059 0.0107 0.0195
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0067 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Brugia malayi PHD-finger family protein 0.0086 0.0167 0.031
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0036 0.0061
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0007
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.2418 0.5403 1
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0022 0.0035
Onchocerca volvulus 0.004 0.0065 0.038
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.001 0.0014
Echinococcus granulosus zinc finger protein 0.0086 0.0167 0.0306
Schistosoma mansoni pyruvate kinase 0.0019 0.0018 0.0028
Echinococcus granulosus bromodomain containing protein 8 0.0084 0.0164 0.0299
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0035 0.0065
Loa Loa (eye worm) intermediate filament protein 0.003 0.0042 0.0073
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0041 0.0067 0.0119
Echinococcus granulosus allatostatin A receptor 0.0059 0.0107 0.0195
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0059 0.0107 0.0195
Onchocerca volvulus 0.003 0.0042 0.0089
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0022 0.0036
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0084 0.0164 0.0852
Schistosoma mansoni cytochrome P450 0.0018 0.0016 0.0026
Brugia malayi hypothetical protein 0.0059 0.0107 0.0199
Trypanosoma cruzi bromodomain-containing protein 3 0.0084 0.0164 0.0299
Trypanosoma brucei AAA ATPase, putative 0.0419 0.0915 0.1691
Loa Loa (eye worm) glutathione reductase 0.0052 0.0093 0.0167
Entamoeba histolytica hypothetical protein 0.0025 0.0032 0.0125
Echinococcus granulosus dro:myosuppressin receptor 0.0059 0.0107 0.0195
Echinococcus multilocularis bromodomain containing 2 0.0791 0.1751 0.3238
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.0084 0.0164 0.0852
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.0256 0.047
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.007 0.0126
Plasmodium vivax bromodomain protein, putative 0.0084 0.0164 0.0299
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0041 0.0067 0.0119
Trichomonas vaginalis reverse transcriptase [C. elegans], putative 0.0027 0.0035 0.0112
Echinococcus granulosus lamin 0.003 0.0042 0.0074
Echinococcus multilocularis 0.0018 0.0016 0.0026
Trypanosoma cruzi Bromodomain, putative 0.0084 0.0164 0.0299
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0058 0.0294
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Loa Loa (eye worm) hypothetical protein 0.0086 0.0167 0.0305
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0419 0.0915 0.1691
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0059 0.0107 0.0195
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0016 0.0025
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0035 0.0061
Toxoplasma gondii bromodomain-containing protein 0.0371 0.0808 0.1481
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0064 0.0115
Echinococcus granulosus tm gpcr rhodopsin 0.0059 0.0107 0.0195
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0315 0.0681 0.1256
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0018 0.0016 0.0015
Brugia malayi MH1 domain containing protein 0.0017 0.0013 0.0024
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0133 0.0274 0.3996
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Echinococcus granulosus pyruvate kinase 0.0037 0.0058 0.0103
Leishmania major hypothetical protein, conserved 0.0084 0.0164 0.0299
Mycobacterium tuberculosis Putative ferredoxin reductase 0.012 0.0244 0.026
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0027 0.0035 0.0246
Giardia lamblia Reverse transcriptase/endonuclease 0.0027 0.0035 0.0246
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0059 0.0107 0.0195
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0016 0.0025
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0256 0.047
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.012 0.0244 0.026
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0026 0.0049
Loa Loa (eye worm) hypothetical protein 0.0084 0.0164 0.0299
Brugia malayi putative neuropeptide receptor 0.0059 0.0107 0.0199
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0067 0.0119
Brugia malayi intermediate filament protein 0.003 0.0042 0.0078
Schistosoma mansoni amine GPCR 0.0059 0.0107 0.0195
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0007 0.0009
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0045 0.0079
Brugia malayi RNase H family protein 0.0316 0.0685 0.1268
Echinococcus granulosus hypothetical protein 0.0059 0.0107 0.0195
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Schistosoma mansoni hypothetical protein 0.0041 0.0067 0.0119
Schistosoma mansoni growth hormone secretagogue receptor 0.0059 0.0107 0.0195
Echinococcus multilocularis acetylcholinesterase 0.1212 0.2696 0.4988
Loa Loa (eye worm) neuropeptide F receptor 0.0059 0.0107 0.0194
Echinococcus granulosus somatostatin receptor 0.0059 0.0107 0.0195
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0624 0.3505
Onchocerca volvulus 0.0041 0.0067 0.0406
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0013 0.0021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.2418 0.5403 1
Mycobacterium ulcerans beta-lactamase 0.004 0.0065 0.0062
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.0294 0.0634 0.117
Echinococcus granulosus smad 0.0017 0.0013 0.002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0146 0.0751
Onchocerca volvulus 0.0059 0.0107 0.0934
Echinococcus granulosus carboxylesterase 5A 0.1212 0.2696 0.4988
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0027 0.0035 0.0061
Echinococcus granulosus cpg binding protein 0.003 0.0043 0.0076
Echinococcus granulosus bromodomain containing 2 0.0791 0.1751 0.3238
Loa Loa (eye worm) hypothetical protein 0.018 0.0379 0.0698
Mycobacterium leprae Conserved hypothetical protein 0.0018 0.0016 0.0202
Loa Loa (eye worm) G-protein coupled receptor 0.0059 0.0107 0.0194
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Entamoeba histolytica bromodomain-containing protein 0.0084 0.0164 0.1804
Schistosoma mansoni blooms syndrome DNA helicase 0.0035 0.0054 0.0096
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.007 0.0126
Brugia malayi Bromodomain containing protein 0.0084 0.0164 0.0303
Trypanosoma brucei Bromodomain factor 1 0.0084 0.0164 0.0299
Brugia malayi polybromodomain protein 0.0084 0.0164 0.0303
Plasmodium falciparum amino acid transporter, putative 0.0041 0.0067 0.0119
Schistosoma mansoni polybromo-1 0.0084 0.0164 0.0299
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Echinococcus multilocularis g protein coupled receptor 0.0059 0.0107 0.0195
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.0016 0.0025
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0018 0.0016 0.0014
Echinococcus multilocularis isocitrate dehydrogenase 0.2418 0.5403 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0314 0.068 0.1255
Schistosoma mansoni isocitrate dehydrogenase 0.0294 0.0634 0.117
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.2418 0.5403 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Mycobacterium ulcerans oxidoreductase 0.0315 0.0681 0.0679
Echinococcus multilocularis musashi 0.003 0.0042 0.0074
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0018 0.0016 0.0026
Trypanosoma cruzi Bromodomain, putative 0.0084 0.0164 0.0299
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Echinococcus granulosus global transcription activator snf2l2 0.0084 0.0164 0.0299
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0016 0.003
Schistosoma mansoni acetylcholinesterase 0.0205 0.0435 0.0801
Brugia malayi Carboxylesterase family protein 0.0205 0.0435 0.0804
Echinococcus multilocularis neuropeptide receptor 0.0059 0.0107 0.0195
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0059 0.0107 0.0195
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0065 0.0115
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.001 0.0014
Schistosoma mansoni pyruvate kinase 0.0037 0.0058 0.0103
Echinococcus multilocularis neuroligin 0.0205 0.0435 0.0801
Echinococcus multilocularis protoporphyrinogen oxidase 0.0315 0.0681 0.1257
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0016 0.0012
Schistosoma mansoni Smad4 0.0017 0.0013 0.002
Schistosoma mansoni hypothetical protein 0.0084 0.0164 0.0299
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Schistosoma mansoni fatty-acid amide hydrolase 0.0102 0.0203 0.0372
Loa Loa (eye worm) hypothetical protein 0.004 0.0065 0.0115
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0013 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Echinococcus multilocularis zinc finger protein 0.0086 0.0167 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0043 0.0075
Brugia malayi bromodomain containing protein 0.0084 0.0164 0.0303
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0016 0.0025
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0018 0.0016 0.0014
Loa Loa (eye worm) serotonin transporter b 0.0241 0.0515 0.095
Echinococcus multilocularis PH interacting protein 0.0084 0.0164 0.0299
Brugia malayi neuropeptide F receptor 0.0059 0.0107 0.0199
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0022 0.0036
Schistosoma mansoni phosphoglucomutase 0.0316 0.0685 0.1264
Echinococcus granulosus neuroligin 0.0205 0.0435 0.0801
Trypanosoma cruzi ribonuclease H1, putative 0.0316 0.0685 0.1264
Giardia lamblia Pyruvate kinase 0.0019 0.0018 0.0023
Brugia malayi jmjC domain containing protein 0.0016 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0042 0.007 0.0125
Treponema pallidum NADH oxidase 0.0018 0.0016 0.0195
Schistosoma mansoni hypothetical protein 0.0027 0.0035 0.0061
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0058 0.0244
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0022 0.0036
Chlamydia trachomatis pyruvate kinase 0.0037 0.0058 0.0819
Onchocerca volvulus 0.0059 0.0107 0.0934
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0032 0.0092
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0037 0.0058 0.006
Echinococcus multilocularis pyruvate kinase 0.0037 0.0058 0.0103
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0027 0.0035 0.0061
Echinococcus granulosus neuropeptides capa receptor 0.0059 0.0107 0.0195
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.001 0.0014
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0059 0.0107 0.0199
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0059 0.0107 0.0194
Echinococcus granulosus sodium and chloride dependent glycine 0.0041 0.0067 0.0119
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0022 0.0036
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0026 0.0044
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0018 0.0016 0.0014
Brugia malayi RNase H family protein 0.0316 0.0685 0.1268
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0009
Loa Loa (eye worm) CBP-B 0.0084 0.0164 0.0299
Echinococcus multilocularis protein kinase C binding protein 1 0.0084 0.0164 0.0299
Brugia malayi hypothetical protein 0.0027 0.0035 0.0065
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Onchocerca volvulus 0.0059 0.0107 0.0934
Schistosoma mansoni jumonji domain containing protein 0.0016 0.001 0.0014
Schistosoma mansoni hypothetical protein 0.0356 0.0773 0.1428
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.4466 1 1
Plasmodium falciparum pyruvate kinase 0.0037 0.0058 0.0103
Loa Loa (eye worm) BRM protein 0.0084 0.0164 0.0299
Echinococcus granulosus Niemann Pick C1 protein 0.0141 0.0292 0.0536
Schistosoma mansoni alpha-1 adrenergic receptor 0.0059 0.0107 0.0195
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0041 0.0067 0.0119
Mycobacterium tuberculosis Carboxylesterase LipT 0.0205 0.0435 0.0465
Echinococcus granulosus fatty acid amide hydrolase 1 0.0102 0.0203 0.0372
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0018 0.0016 0.0015
Echinococcus granulosus g protein coupled receptor 0.0059 0.0107 0.0195
Loa Loa (eye worm) hypothetical protein 0.0205 0.0435 0.08
Loa Loa (eye worm) hypothetical protein 0.0102 0.0203 0.0372
Toxoplasma gondii histone lysine-specific demethylase 0.0315 0.0681 0.1245
Mycobacterium ulcerans 3-isopropylmalate dehydrogenase 0.0294 0.0634 0.0632
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0093 0.0167
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0079
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.001 0.0014
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.0016 0.0195
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.007 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Trypanosoma cruzi Bromodomain factor 1 0.0084 0.0164 0.0299
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0059 0.0107 0.0199
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0059 0.0107 0.0195
Leishmania major cytochrome p450-like protein 0.0018 0.0016 0.0025
Loa Loa (eye worm) neuropeptide F receptor 0.0059 0.0107 0.0194
Onchocerca volvulus 0.004 0.0065 0.038
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0205 0.0435 0.0801
Loa Loa (eye worm) hypothetical protein 0.0084 0.0164 0.0299
Echinococcus granulosus G protein coupled receptor 139 0.0059 0.0107 0.0195
Schistosoma mansoni zinc finger protein 0.0086 0.0167 0.0306
Schistosoma mansoni hypothetical protein 0.0335 0.0727 0.1341
Plasmodium vivax SET domain containing protein 0.0086 0.0167 0.0306
Echinococcus multilocularis fmrfamide receptor 0.0059 0.0107 0.0195
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0026 0.0045
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0013 0.002
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.2418 0.5403 1
Schistosoma mansoni ran 0.0023 0.0026 0.0045
Brugia malayi beta-lactamase 0.004 0.0065 0.0119
Onchocerca volvulus 0.0241 0.0515 0.6209
Leishmania major cytochrome p450-like protein 0.0018 0.0016 0.0025
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0036 0.0049
Brugia malayi Inositol-1 0.004 0.0064 0.0119
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0205 0.0435 0.0801
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0065 0.0115
Plasmodium vivax pyruvate kinase, putative 0.0037 0.0058 0.0103
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.012 0.0244 0.026
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.001 0.0014
Brugia malayi hypothetical protein 0.0205 0.0435 0.0804
Echinococcus multilocularis pyruvate kinase 0.0019 0.0018 0.0028
Brugia malayi G protein-coupled receptor F59B2.13 0.0059 0.0107 0.0199
Brugia malayi hypothetical protein 0.0059 0.0107 0.0199
Schistosoma mansoni hypothetical protein 0.0018 0.0016 0.0026
Loa Loa (eye worm) hypothetical protein 0.0084 0.0164 0.0299
Leishmania major trypanothione reductase 0.0052 0.0093 0.0167
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0058 0.0103
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0118 0.0218
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0059 0.0107 0.0195
Echinococcus multilocularis sodium and chloride dependent glycine 0.0041 0.0067 0.0119
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0016 0.0025
Schistosoma mansoni neuropeptide receptor 0.0059 0.0107 0.0195
Echinococcus granulosus lysine specific histone demethylase 1A 0.0315 0.0681 0.1257
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0029 0.0048
Brugia malayi cytochrome P450 0.0018 0.0016 0.003
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0059 0.0107 0.0195
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0041 0.0067 0.0119
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0076 0.0146 0.1645
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0109 0.0198
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0018 0.0016 0.0014
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0018 0.0016 0.0013
Brugia malayi polybromodomain protein 0.0084 0.0164 0.0303
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0059 0.0107 0.0195
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0316 0.0685 0.1252
Schistosoma mansoni survival motor neuron protein 0.0047 0.008 0.0144
Plasmodium falciparum bromodomain protein 2, putative 0.0084 0.0164 0.0299
Echinococcus multilocularis somatostatin receptor 0.0059 0.0107 0.0195
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0256 0.0254
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Schistosoma mansoni helicase 0.0084 0.0164 0.0299
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0016 0.0025
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0035 0.0065
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0059 0.0107 0.0194
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.007 0.0126
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0086 0.0167 0.0306
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0067 0.0123
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0064 0.0281
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0076 0.0146 0.158
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.0005 0.0009
Schistosoma mansoni amine GPCR 0.0059 0.0107 0.0195
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.0294 0.0634 0.117
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0013 0.002
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.001 0.0014
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.0005 0.0009
Trypanosoma cruzi ribonuclease H1, putative 0.0316 0.0685 0.1264
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0027 0.0035 0.0246
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0059 0.0107 0.0195
Echinococcus granulosus neuropeptide receptor 0.0059 0.0107 0.0195
Entamoeba histolytica bromodomain-containing protein 0.0084 0.0164 0.1804
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.164 0.3655 0.6764
Toxoplasma gondii histone lysine methyltransferase SET1 0.014 0.0289 0.0517
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0118 0.0213
Schistosoma mansoni lamin 0.003 0.0042 0.0074
Schistosoma mansoni hypothetical protein 0.0084 0.0164 0.0299
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0315 0.0681 0.1256
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0016 0.0025
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0035 0.0061
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0027 0.0035 0.0061
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0067 0.0119
Echinococcus granulosus 7tm_1 domain containing protein 0.0059 0.0107 0.0195
Brugia malayi Smad1 0.0017 0.0013 0.0024
Echinococcus multilocularis g-protein coupled receptor 0.0059 0.0107 0.0195
Mycobacterium tuberculosis Conserved protein 0.004 0.0065 0.0067
Echinococcus multilocularis dro:myosuppressin receptor 0.0059 0.0107 0.0195
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0027 0.0035 0.0246
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.008 0.0148
Loa Loa (eye worm) hypothetical protein 0.018 0.0379 0.0698
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0018 0.0016 0.0026
Mycobacterium ulcerans monoamine oxidase 0.0315 0.0681 0.0679
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.2418 0.5403 1
Trichomonas vaginalis hypothetical protein 0.0084 0.0164 0.0852
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0084 0.0164 0.0852
Brugia malayi hypothetical protein 0.0027 0.0036 0.0067
Loa Loa (eye worm) solute carrier family 6 member 4 0.0241 0.0515 0.095
Toxoplasma gondii bromodomain-containing protein 0.0084 0.0164 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Brugia malayi hypothetical protein 0.0059 0.0107 0.0199
Trichomonas vaginalis hypothetical protein 0.0084 0.0164 0.0852
Schistosoma mansoni bromodomain containing protein 0.0086 0.0167 0.0306
Echinococcus multilocularis pyruvate kinase 0.0019 0.0018 0.0028
Loa Loa (eye worm) hypothetical protein 0.004 0.0065 0.0115
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0035 0.0065
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.0109 0.0198
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0064 0.0115
Brugia malayi Bromodomain containing protein 0.0084 0.0164 0.0303
Trichomonas vaginalis bromodomain containing protein, putative 0.0084 0.0164 0.0852
Brugia malayi Dopamine receptor protein 1 0.0059 0.0107 0.0199
Onchocerca volvulus Ribonuclease H1 homolog 0.0316 0.0685 0.8408
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.0292 0.0312
Plasmodium falciparum thioredoxin reductase 0.0052 0.0093 0.0167
Loa Loa (eye worm) hypothetical protein 0.0205 0.0435 0.08
Onchocerca volvulus 0.0059 0.0107 0.0934
Toxoplasma gondii exonuclease III APE 0.0021 0.0022 0.0022
Plasmodium vivax pyruvate kinase 2, putative 0.0019 0.0018 0.0028
Schistosoma mansoni hypothetical protein 0.0041 0.0067 0.0119
Brugia malayi glutathione reductase 0.0052 0.0093 0.0171
Trypanosoma brucei pyruvate kinase 1, putative 0.0037 0.0058 0.0103
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.0016 0.0025
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0018 0.0016 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0016 0.0025
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0036 0.0062
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0624 0.3505
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.2418 0.5403 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.2418 0.5403 1
Echinococcus granulosus sodium and chloride dependent glycine 0.0041 0.0067 0.0119
Loa Loa (eye worm) hypothetical protein 0.0041 0.0067 0.0119
Brugia malayi hypothetical protein 0.0059 0.0107 0.0199
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0315 0.0681 0.1257
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.0084 0.0164 0.0852
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.0256 0.0273
Loa Loa (eye worm) hypothetical protein 0.1212 0.2696 0.4988
Loa Loa (eye worm) hypothetical protein 0.003 0.0043 0.0074
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0127 0.0259 0.0463
Entamoeba histolytica hypothetical protein 0.0084 0.0164 0.1804
Loa Loa (eye worm) hypothetical protein 0.0026 0.0033 0.0056
Loa Loa (eye worm) hypothetical protein 0.0099 0.0197 0.036
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0035 0.0061
Loa Loa (eye worm) hypothetical protein 0.0205 0.0435 0.08
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0016 0.0025
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0065 0.0067
Toxoplasma gondii isocitrate dehydrogenase 0.2418 0.5403 1
Loa Loa (eye worm) bromodomain containing protein 0.0371 0.0808 0.1492
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0035 0.0065
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0026 0.0044
Schistosoma mansoni ap endonuclease 0.0021 0.0022 0.0036
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0022 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0036 0.0061
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0064 0.0281
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.0016 0.0026
Brugia malayi Tachykinin-like peptides receptor 99D 0.0059 0.0107 0.0199
Leishmania major DNA-binding protein, putative,predicted bromodomain protein 0.0084 0.0164 0.0299
Plasmodium vivax hypothetical protein, conserved 0.0084 0.0164 0.0299
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Plasmodium vivax SET domain protein, putative 0.003 0.0043 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Echinococcus granulosus bloom syndrome protein 0.0045 0.0075 0.0135
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.001 0.0014
Trypanosoma brucei Bromodomain, putative 0.0084 0.0164 0.0299
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0076 0.0146 0.0266
Loa Loa (eye worm) hypothetical protein 0.0205 0.0435 0.08
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0043 0.0061
Schistosoma mansoni neuropeptide f receptor 76f 0.0059 0.0107 0.0195
Echinococcus granulosus serotonin receptor 0.0059 0.0107 0.0195
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0059 0.0107 0.0195
Echinococcus granulosus para nitrobenzyl esterase 0.0205 0.0435 0.0801
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Loa Loa (eye worm) hypothetical protein 0.0041 0.0067 0.0119
Leishmania major pyruvate kinase 0.0037 0.0058 0.0103
Onchocerca volvulus 0.0315 0.0681 0.8353
Trypanosoma brucei isocitrate dehydrogenase, putative 0.2418 0.5403 1
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Brugia malayi ORL1-like opioid receptor 0.0059 0.0107 0.0199
Entamoeba histolytica bromodomain-containing protein 0.0371 0.0808 1
Trichomonas vaginalis reverse transcriptases, putative 0.0027 0.0035 0.0112
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Brugia malayi CXXC zinc finger family protein 0.0029 0.004 0.0073
Loa Loa (eye worm) hypothetical protein 0.004 0.0065 0.0115
Loa Loa (eye worm) norepinephrine transporter 0.0241 0.0515 0.095
Brugia malayi Probable isocitrate dehydrogenase 0.0294 0.0634 0.1174
Brugia malayi Bromodomain containing protein 0.0084 0.0164 0.0303
Brugia malayi hypothetical protein 0.0287 0.0619 0.1147
Schistosoma mansoni bromodomain containing protein 0.0084 0.0164 0.0299
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.0016 0.0025
Schistosoma mansoni scy1(yeast) protein kinase-like 0.0027 0.0035 0.0061
Wolbachia endosymbiont of Brugia malayi isocitrate dehydrogenase 0.0294 0.0634 0.9253
Loa Loa (eye worm) hypothetical protein 0.0205 0.0435 0.08
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0041 0.0067 0.0119
Brugia malayi Cytochrome P450 family protein 0.0027 0.0036 0.0066
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0059 0.0107 0.0199
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Loa Loa (eye worm) pyruvate kinase-PB 0.0026 0.0033 0.0056
Brugia malayi hypothetical protein 0.0041 0.0067 0.0123
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0075 0.0344
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0027 0.0035 0.0246
Plasmodium vivax hypothetical protein, conserved 0.004 0.0065 0.0115
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0026 0.0045
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.0256 0.0456
Echinococcus granulosus tachykinin peptides receptor 99D 0.0059 0.0107 0.0195
Mycobacterium ulcerans dehydrogenase 0.0315 0.0681 0.0679
Toxoplasma gondii pyruvate kinase PyK1 0.0037 0.0058 0.0089
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0059 0.0107 0.0195
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0018 0.0016 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0043 0.0075
Toxoplasma gondii hypothetical protein 0.0084 0.0164 0.0285
Brugia malayi Thioredoxin reductase 0.0052 0.0093 0.0171
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0022 0.0036
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0146 0.0751
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0018 0.0016 0.0014
Echinococcus granulosus histone acetyltransferase KAT2B 0.0154 0.0319 0.0587
Schistosoma mansoni amine oxidase 0.0315 0.0681 0.1257
Loa Loa (eye worm) hypothetical protein 0.0084 0.0164 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Schistosoma mansoni amine GPCR 0.0059 0.0107 0.0195
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0064 0.0115
Onchocerca volvulus 0.0205 0.0435 0.5168
Brugia malayi hypothetical protein 0.0059 0.0107 0.0199
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0059 0.0107 0.0194
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0016 0.0029
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0205 0.0435 0.2414
Trichomonas vaginalis conserved hypothetical protein 0.042 0.0918 0.5198
Echinococcus multilocularis g protein coupled receptor 0.0059 0.0107 0.0195
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0065 0.0062
Giardia lamblia Sgs1 DNA helicase, putative 0.0018 0.0016 0.0009
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0118 0.0214
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0018 0.0016 0.0015
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0018 0.0016 0.0014
Schistosoma mansoni myosin xvIII 0.0059 0.0107 0.0195
Trichomonas vaginalis bromodomain-containing protein, putative 0.0791 0.1751 1
Brugia malayi Serotonin receptor 0.0517 0.1135 0.2101
Loa Loa (eye worm) isocitrate dehydrogenase 0.2418 0.5403 1
Brugia malayi follicle stimulating hormone receptor 0.0314 0.068 0.1259
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0026 0.0044
Trichomonas vaginalis set domain proteins, putative 0.0235 0.0502 0.2805
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Brugia malayi jmjC domain containing protein 0.0016 0.001 0.0018
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Trypanosoma cruzi Bromodomain, putative 0.0084 0.0164 0.0299
Trichomonas vaginalis ribonuclease H1, putative 0.0316 0.0685 0.3858
Echinococcus multilocularis ribonuclease H1 0.0316 0.0685 0.1264
Brugia malayi TAR-binding protein 0.0064 0.0118 0.0218
Brugia malayi AKH receptor 0.0059 0.0107 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0067 0.0119
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0035 0.0061
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0419 0.0915 0.1691
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.0093 0.0167
Schistosoma mansoni inositol monophosphatase 0.004 0.0064 0.0115
Brugia malayi RE15519p 0.0059 0.0107 0.0199
Schistosoma mansoni histamine h1 receptor 0.0059 0.0107 0.0195
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.0075 0.014
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Trypanosoma cruzi Bromodomain, putative 0.0084 0.0164 0.0299
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0018 0.0016 0.0014
Echinococcus multilocularis smad 0.0017 0.0013 0.002
Echinococcus granulosus neuropeptide receptor A26 0.0514 0.1129 0.2086
Mycobacterium ulcerans pyruvate kinase 0.0037 0.0058 0.0056
Mycobacterium leprae PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) 0.0294 0.0634 0.9311
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Toxoplasma gondii bromodomain-containing protein 0.0084 0.0164 0.0285
Brugia malayi hypothetical protein 0.0059 0.0107 0.0199
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0013 0.0019
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0016 0.0025
Echinococcus granulosus BC026374 protein S09 family 0.0205 0.0435 0.0801
Trichomonas vaginalis bromodomain containing protein, putative 0.0371 0.0808 0.4567
Brugia malayi acetyltransferase, GNAT family protein 0.0238 0.0509 0.0943
Schistosoma mansoni cpg binding protein 0.0029 0.004 0.0069
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.0294 0.0634 0.1174
Schistosoma mansoni smad1 5 8 and 0.0017 0.0013 0.002
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0067 0.0119
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.001 0.0014
Trypanosoma cruzi Bromodomain, putative 0.0084 0.0164 0.0299
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0107 0.0195
Brugia malayi hypothetical protein 0.0027 0.0035 0.0065
Echinococcus multilocularis dnaJ subfamily B 0.0411 0.0897 0.1656
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0018 0.0016 0.0196
Echinococcus granulosus CREB binding protein 0.0084 0.0164 0.0299
Echinococcus granulosus Bromodomain containing protein 0.0084 0.0164 0.0299
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0238 0.0509 0.0939
Giardia lamblia Fructose-bisphosphate aldolase 0.0289 0.0624 0.7675
Echinococcus multilocularis protein dispatched 1 0.0048 0.0084 0.015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Brugia malayi neuropeptide F receptor 0.0059 0.0107 0.0199
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0016 0.0025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Echinococcus multilocularis BC026374 protein (S09 family) 0.0205 0.0435 0.0801
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0238 0.0509 0.0939
Brugia malayi hypothetical protein 0.023 0.0491 0.0908
Plasmodium falciparum glutathione reductase 0.0052 0.0093 0.0167
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0076 0.0146 0.0266
Onchocerca volvulus 0.0029 0.004 0.0057
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Schistosoma mansoni smad1 5 8 and 0.0017 0.0013 0.002
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0035 0.0065
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0084 0.0164 0.0299
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0018 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0007
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Trypanosoma cruzi UDP-galactopyranose mutase 0.0315 0.0681 0.1256
Onchocerca volvulus 0.0205 0.0435 0.5168
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.0294 0.0634 0.1174
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0064 0.0281
Brugia malayi G protein-coupled receptor 0.0059 0.0107 0.0199
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0059 0.0107 0.0194
Brugia malayi Bromodomain containing protein 0.0086 0.0167 0.031
Trichomonas vaginalis glutaminase, putative 0.0566 0.1245 0.7084
Plasmodium vivax hypothetical protein, conserved 0.0315 0.0681 0.1256
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0043 0.0075
Echinococcus granulosus neuropeptide s receptor 0.0514 0.1129 0.2086
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0085 0.0165 0.086
Schistosoma mansoni hypothetical protein 0.0059 0.0107 0.0195
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0065 0.0115
Trypanosoma brucei trypanothione reductase 0.0052 0.0093 0.0167
Leishmania major hypothetical protein, conserved,predicted bromodomain protein 0.0084 0.0164 0.0299
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Schistosoma mansoni hypothetical protein 0.0059 0.0107 0.0195
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0064 0.0115
Loa Loa (eye worm) hypothetical protein 0.0052 0.0091 0.0165
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Brugia malayi BRM protein 0.0084 0.0164 0.0303
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Brugia malayi Bromodomain containing protein 0.0084 0.0164 0.0303
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0256 0.0254
Trypanosoma cruzi bromodomain factor 2 protein 0.0084 0.0164 0.0299
Echinococcus granulosus acetylcholinesterase 0.1212 0.2696 0.4988
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0036 0.0061
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0016 0.003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Schistosoma mansoni biogenic amine receptor 0.0059 0.0107 0.0195
Onchocerca volvulus 0.0047 0.008 0.0581
Echinococcus granulosus neuropeptide FF receptor 2 0.0059 0.0107 0.0195
Brugia malayi Cytochrome P450 family protein 0.0018 0.0016 0.003
Trypanosoma brucei hypothetical protein, conserved 0.0343 0.0745 0.1376
Echinococcus multilocularis pyruvate kinase 0.0019 0.0018 0.0028
Brugia malayi isocitrate dehydrogenase 0.2418 0.5403 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0076 0.0146 0.0266
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0146 0.0266
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0107 0.0195
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0045 0.0065
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0036 0.0062
Brugia malayi Niemann-Pick C1 protein precursor 0.0099 0.0197 0.0364
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0058 0.0244
Echinococcus granulosus neuropeptide receptor 0.0059 0.0107 0.0195
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0059 0.0107 0.0195
Echinococcus multilocularis neuropeptide receptor 0.0059 0.0107 0.0195
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Schistosoma mansoni neuropeptide F-like receptor 0.0059 0.0107 0.0195
Echinococcus granulosus alpha 1A adrenergic receptor 0.0059 0.0107 0.0195
Schistosoma mansoni hypothetical protein 0.0084 0.0164 0.0299
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0007 0.0009
Echinococcus granulosus biogenic amine 5HT receptor 0.018 0.0379 0.0698
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0084 0.0164 0.0285
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0041 0.0067 0.0119
Trichomonas vaginalis lymphoid specific helicase, putative 0.0084 0.0164 0.0852
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0064 0.0115
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0016 0.0025
Schistosoma mansoni smad 0.0017 0.0013 0.002
Echinococcus granulosus ubiquitin specific protease 41 0.0076 0.0146 0.0266
Trypanosoma brucei bromodomain factor 2 protein, putative 0.0084 0.0164 0.0299
Schistosoma mansoni cpg binding protein 0.003 0.0043 0.0076
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0067 0.0105
Trichomonas vaginalis bromodomain-containing protein, putative 0.0504 0.1106 0.6285
Echinococcus multilocularis neuropeptide Y receptor 0.0059 0.0107 0.0195
Trichomonas vaginalis bromodomain-containing protein, putative 0.0504 0.1106 0.6285
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0016 0.0025
Trypanosoma cruzi UDP-galactopyranose mutase 0.0315 0.0681 0.1256
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0016 0.0025
Echinococcus granulosus pyruvate kinase 0.0019 0.0018 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0043 0.0075
Loa Loa (eye worm) RNA binding protein 0.0064 0.0118 0.0213
Echinococcus multilocularis neuropeptide FF receptor 2 0.0059 0.0107 0.0195
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0059 0.0107 0.0195
Toxoplasma gondii histone acetyltransferase TAF1/250 0.0084 0.0164 0.0285
Loa Loa (eye worm) hypothetical protein 0.004 0.0065 0.0115
Echinococcus multilocularis bromodomain containing protein 8 0.0084 0.0164 0.0299
Echinococcus granulosus polybromo 1 0.0084 0.0164 0.0299
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0062
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Loa Loa (eye worm) hypothetical protein 0.0241 0.0515 0.095
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0076 0.0146 0.027
Loa Loa (eye worm) G-protein coupled receptor 0.0059 0.0107 0.0194
Onchocerca volvulus 0.003 0.0042 0.0089
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0018 0.0016 0.0015
Echinococcus granulosus Niemann Pick C1 protein 0.0099 0.0197 0.036
Brugia malayi Bromodomain containing protein 0.0084 0.0164 0.0303
Brugia malayi Zinc knuckle family protein 0.0027 0.0035 0.0065
Echinococcus multilocularis global transcription activator snf2l2 0.0084 0.0164 0.0299
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0118 0.0214
Onchocerca volvulus 0.0205 0.0435 0.5168
Schistosoma mansoni opsin-like receptor 0.0059 0.0107 0.0195
Loa Loa (eye worm) hypothetical protein 0.0041 0.0067 0.0119
Leishmania major ribonuclease H1, putative 0.0316 0.0685 0.1264
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Loa Loa (eye worm) hypothetical protein 0.004 0.0065 0.0115
Trichomonas vaginalis bromodomain-containing protein, putative 0.0127 0.0259 0.1403
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0016 0.0025
Echinococcus multilocularis polybromo 1 0.0084 0.0164 0.0299
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0018 0.0016 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0118 0.0214
Loa Loa (eye worm) hypothetical protein 0.0041 0.0067 0.0119
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Brugia malayi jmjC domain containing protein 0.0016 0.001 0.0018
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.0294 0.0634 0.117
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0035 0.0061
Schistosoma mansoni DNA helicase recq5 0.0018 0.0016 0.0026
Schistosoma mansoni opsin-like receptor 0.0059 0.0107 0.0195
Echinococcus multilocularis para nitrobenzyl esterase 0.0205 0.0435 0.0801
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0064 0.0909
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0036 0.0061
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.0292 0.029
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0067 0.0119
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0035 0.0065
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.001 0.0014
Echinococcus multilocularis cpg binding protein 0.003 0.0043 0.0076
Brugia malayi CHE-14 protein 0.0042 0.007 0.013
Mycobacterium ulcerans lipase LipD 0.004 0.0065 0.0062
Schistosoma mansoni biogenic amine (5HT) receptor 0.018 0.0379 0.0698
Loa Loa (eye worm) cytochrome P450 0.0018 0.0016 0.0025
Echinococcus multilocularis sex peptide receptor 0.0059 0.0107 0.0195
Giardia lamblia Pyruvate kinase 0.0037 0.0058 0.0533
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0036 0.0033
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0036 0.0061
Brugia malayi MH2 domain containing protein 0.0249 0.0533 0.0986
Brugia malayi hypothetical protein 0.0059 0.0107 0.0199
Leishmania major GTP-binding protein, putative 0.0023 0.0026 0.0044
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.007 0.062
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0107 0.0195
Toxoplasma gondii cytochrome p450 superfamily protein 0.0018 0.0016 0.0012
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0035 0.0065
Echinococcus granulosus pyruvate kinase 0.0019 0.0018 0.0028
Trypanosoma brucei SLACS retrotransposable element (part), putative 0.0027 0.0035 0.0061
Mycobacterium leprae Probable lipase LipE 0.004 0.0065 0.0916
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0205 0.0435 0.0801
Brugia malayi RNase H family protein 0.0316 0.0685 0.1268
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0045 0.0079
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0026 0.0044
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0059 0.0107 0.0195
Trichomonas vaginalis esterase, putative 0.004 0.0065 0.0282
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0026
Echinococcus multilocularis protein patched 0.0042 0.007 0.0126
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0059 0.0107 0.0195
Mycobacterium tuberculosis Conserved protein 0.004 0.0065 0.0067
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0026 0.0044
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0013 0.002
Plasmodium vivax glutathione reductase, putative 0.0052 0.0093 0.0167
Brugia malayi putative neuropeptide receptor NPR1 0.0059 0.0107 0.0199
Entamoeba histolytica ankyrin repeat protein, putative 0.0084 0.0164 0.1804
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0043 0.0075
Giardia lamblia Ribonuclease H 0.0316 0.0685 0.8447
Schistosoma mansoni hypothetical protein 0.0411 0.0897 0.1656
Echinococcus granulosus RNA directed DNA polymerase 0.0027 0.0035 0.0061
Mycobacterium ulcerans hypothetical protein 0.004 0.0065 0.0062
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0059 0.0107 0.0195
Schistosoma mansoni neuropeptide receptor 0.0059 0.0107 0.0195
Onchocerca volvulus 0.0059 0.0107 0.0934
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0127 0.0259 0.0476
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0011 0.002
Brugia malayi Bromodomain containing protein 0.0084 0.0164 0.0303
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0065 0.0282
Trypanosoma cruzi hypothetical protein, conserved 0.0084 0.0164 0.0299
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.4152 0.9294 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0256 0.0254
Schistosoma mansoni hypothetical protein 0.0041 0.0067 0.0119
Echinococcus granulosus fatty acid amide hydrolase 1 0.0102 0.0203 0.0372
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0107 0.0195
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0016 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0118 0.0214
Loa Loa (eye worm) hypothetical protein 0.0315 0.0681 0.1256
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Echinococcus granulosus pyruvate kinase 0.0037 0.0058 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Trypanosoma brucei pyruvate kinase 1 0.0037 0.0058 0.0103
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0205 0.0435 0.0801
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0241 0.0515 0.0954
Echinococcus multilocularis Bromodomain containing protein 0.0084 0.0164 0.0299
Echinococcus granulosus dnaJ subfamily B 0.0411 0.0897 0.1656
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0063 0.0113
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.0093 0.0167
Schistosoma mansoni phd finger protein 0.0084 0.0164 0.0299
Onchocerca volvulus 0.0059 0.0107 0.0934
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Brugia malayi amidase 0.0102 0.0203 0.0376
Brugia malayi RNA binding protein 0.0064 0.0118 0.0218
Toxoplasma gondii pyruvate kinase PyKII 0.0019 0.0018 0.0014
Echinococcus multilocularis lamin dm0 0.003 0.0042 0.0074
Brugia malayi jmjC domain containing protein 0.006 0.0109 0.0202
Plasmodium falciparum bromodomain protein 1 0.0084 0.0164 0.0299
Mycobacterium tuberculosis Probable dehydrogenase 0.012 0.0244 0.026
Trichomonas vaginalis bromodomain containing protein, putative 0.0084 0.0164 0.0852
Echinococcus multilocularis g protein coupled receptor 0.0059 0.0107 0.0195
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0018 0.0016 0.0014
Onchocerca volvulus 0.0059 0.0107 0.0934
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0042 0.006
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Plasmodium falciparum thioredoxin reductase 0.0018 0.0016 0.0025
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0315 0.0681 0.1257
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0018 0.0016 0.0015
Brugia malayi Dopamine receptor 0.0059 0.0107 0.0199
Schistosoma mansoni amine GPCR 0.0059 0.0107 0.0195
Treponema pallidum sodium- and chloride- dependent transporter 0.0241 0.0515 0.751
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0205 0.0435 0.0801
Loa Loa (eye worm) hypothetical protein 0.0029 0.0041 0.0071
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0059 0.0107 0.0934
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0022 0.0076
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Echinococcus multilocularis phd:f box containing protein 0.0016 0.001 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0035 0.0065
Trypanosoma brucei ingi protein (ORF1) 0.0343 0.0745 0.1376
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0118 0.0213
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0013 0.002
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0041 0.0067 0.0123
Echinococcus granulosus lamin dm0 0.003 0.0042 0.0074
Echinococcus multilocularis orexin receptor type 2 0.0059 0.0107 0.0195
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.0016 0.0025
Echinococcus granulosus Smad4 0.0017 0.0013 0.002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Entamoeba histolytica bromodomain-containing protein 0.0371 0.0808 1
Echinococcus multilocularis geminin 0.0356 0.0773 0.1428
Echinococcus granulosus g-protein coupled receptor 0.0059 0.0107 0.0195
Schistosoma mansoni sodium/chloride dependent transporter 0.0241 0.0515 0.095
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0065 0.0115
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0035 0.0065
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0045 0.0079
Loa Loa (eye worm) glutaminase 2 0.0566 0.1245 0.2301
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0016 0.0025
Plasmodium falciparum importin beta, putative 0.0031 0.0045 0.0079
Schistosoma mansoni neuropeptide F-like receptor 0.0059 0.0107 0.0195
Echinococcus granulosus isocitrate dehydrogenase NAD 0.0294 0.0634 0.117
Loa Loa (eye worm) hypothetical protein 0.0315 0.0681 0.1256
Loa Loa (eye worm) hypothetical protein 0.0791 0.1751 0.3238
Brugia malayi Carboxylesterase family protein 0.0205 0.0435 0.0804
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0032 0.0092
Loa Loa (eye worm) hypothetical protein 0.0205 0.0435 0.08
Trichomonas vaginalis bromodomain containing protein, putative 0.0504 0.1106 0.6285
Trichomonas vaginalis reverse transcriptases, putative 0.0027 0.0035 0.0112
Echinococcus multilocularis 0.0315 0.0681 0.1257
Echinococcus multilocularis carboxylesterase 5A 0.1212 0.2696 0.4988
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.0294 0.0634 0.117
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0026 0.0134
Toxoplasma gondii bromodomain-containing protein 0.0084 0.0164 0.0285
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0035 0.0065
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Chlamydia trachomatis protoporphyrinogen oxidase 0.0315 0.0681 1
Mycobacterium ulcerans carboxylesterase, LipT 0.0205 0.0435 0.0432
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0065 0.0282
Echinococcus multilocularis snurportin 1 0.0333 0.0721 0.1332
Loa Loa (eye worm) hypothetical protein 0.0315 0.0681 0.1256
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0103
Schistosoma mansoni neuroligin 3 (S09 family) 0.0205 0.0435 0.0801
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0067 0.0119
Brugia malayi G-protein coupled receptor 0.0059 0.0107 0.0199
Leishmania major hypothetical protein, conserved 0.004 0.0065 0.0115
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0059 0.0107 0.0195
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Schistosoma mansoni hypothetical protein 0.0047 0.008 0.0144
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0029 0.0048
Onchocerca volvulus 0.0205 0.0435 0.5168
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0624 0.3505
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0065 0.0115
Loa Loa (eye worm) hypothetical protein 0.1212 0.2696 0.4988
Onchocerca volvulus 0.0235 0.0502 0.6043
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Brugia malayi beta-lactamase family protein 0.004 0.0065 0.0119
Trypanosoma cruzi ATPase, putative 0.0335 0.0727 0.1341
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0107 0.0195
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0016 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Loa Loa (eye worm) hypothetical protein 0.0086 0.0167 0.0305
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0026 0.0031
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0059 0.0107 0.0195
Echinococcus granulosus importin subunit beta 1 0.0031 0.0045 0.0079
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0027 0.0035 0.0061
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0013 0.002
Echinococcus multilocularis neuropeptides capa receptor 0.0059 0.0107 0.0195
Brugia malayi Pyruvate kinase, muscle isozyme 0.0037 0.0058 0.0107
Schistosoma mansoni hypothetical protein 0.1187 0.2638 0.4881
Echinococcus granulosus transcription initiation factor TFIID subunit 1 0.0084 0.0164 0.0299
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0315 0.0681 0.0679
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0018 0.0016 0.0014
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0018 0.0016 0.0014
Giardia lamblia Hypothetical protein 0.0084 0.0164 0.1867
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0067 0.0123
Brugia malayi amine oxidase, flavin-containing family protein 0.0315 0.0681 0.126
Echinococcus granulosus pyruvate kinase 0.0019 0.0018 0.0028
Echinococcus multilocularis serotonin receptor 0.018 0.0379 0.0698
Schistosoma mansoni gliotactin 0.0205 0.0435 0.0801
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0035 0.0065
Loa Loa (eye worm) hypothetical protein 0.0041 0.0067 0.0119
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0058 0.0103
Onchocerca volvulus 0.0059 0.0107 0.0934
Brugia malayi TAZ zinc finger family protein 0.0084 0.0164 0.0303
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0022 0.0036
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0032 0.0092
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0027 0.0035 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Echinococcus granulosus acetylcholinesterase 0.1212 0.2696 0.4988
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0109 0.0198
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.2418 0.5403 1
Echinococcus multilocularis Smad4 0.0017 0.0013 0.002
Schistosoma mansoni bromodomain containing 0.0084 0.0164 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Echinococcus multilocularis allatostatin A receptor 0.0059 0.0107 0.0195
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0018 0.0016 0.0015
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.0491 0.0905
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.001 0.0014
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0016 0.0025
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0105 0.0191
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0036 0.0062
Schistosoma mansoni biogenic amine (5HT) receptor 0.0059 0.0107 0.0195
Loa Loa (eye worm) inositol-1 0.004 0.0064 0.0115
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Loa Loa (eye worm) hypothetical protein 0.0315 0.0681 0.1256
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0016 0.0025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0256 0.047
Echinococcus multilocularis Niemann Pick C1 protein 0.0099 0.0197 0.036
Entamoeba histolytica bromodomain-containing protein 0.0371 0.0808 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Brugia malayi Melatonin receptor type 1A 0.0059 0.0107 0.0199
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0065 0.0282
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Loa Loa (eye worm) hypothetical protein 0.004 0.0065 0.0115
Trichomonas vaginalis bromodomain-containing protein, putative 0.0504 0.1106 0.6285
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0065 0.0067
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0036 0.0062
Loa Loa (eye worm) Smad1 0.0017 0.0013 0.0019
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.001 0.0014
Onchocerca volvulus 0.0059 0.0107 0.0934
Trypanosoma brucei SLACS reverse transcriptase, putative 0.0027 0.0035 0.0061
Onchocerca volvulus 0.0041 0.0067 0.0406
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0086 0.0167 0.0306
Onchocerca volvulus 0.0205 0.0435 0.5168
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0018 0.0016 0.0014
Schistosoma mansoni protein kinase 0.0027 0.0035 0.0061
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0105 0.0191
Brugia malayi Zinc knuckle family protein 0.0027 0.0035 0.0065
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Onchocerca volvulus 0.0041 0.0067 0.0406
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Trichomonas vaginalis bromodomain containing protein, putative 0.0084 0.0164 0.0852
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0018 0.0016 0.0015
Schistosoma mansoni hypothetical protein 0.0084 0.0164 0.0299
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0065 0.0282
Loa Loa (eye worm) hypothetical protein 0.0084 0.0164 0.0299
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0059 0.0107 0.0195
Echinococcus granulosus snurportin 1 0.0333 0.0721 0.1332
Loa Loa (eye worm) hypothetical protein 0.0076 0.0146 0.0266
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0014
Giardia lamblia Transcription regulatory protein SNF2 0.0084 0.0164 0.1867
Echinococcus granulosus CREB binding protein 0.0084 0.0164 0.0299
Brugia malayi jmjC domain containing protein 0.0058 0.0105 0.0195
Loa Loa (eye worm) acetyltransferase 0.0238 0.0509 0.0939
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0065 0.0282
Trypanosoma brucei unspecified product 0.0343 0.0745 0.1376
Schistosoma mansoni DNA helicase recq1 0.0018 0.0016 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0018 0.0016 0.0015
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0022 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0018 0.0016 0.0015
Schistosoma mansoni sodium/chloride dependent transporter 0.0041 0.0067 0.0119
Loa Loa (eye worm) hypothetical protein 0.0315 0.0681 0.1256
Echinococcus multilocularis serotonin receptor 0.018 0.0379 0.0698
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.2418 0.5403 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0146 0.0751
Brugia malayi Dopamine receptor protein 2 0.0059 0.0107 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.012 0.0244 0.026
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.0016 0.0026
Schistosoma mansoni unc-13 (munc13) 0.0294 0.0634 0.117
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0018 0.0016 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0107 0.0195
Loa Loa (eye worm) carboxylesterase 0.1212 0.2696 0.4988
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0059 0.0107 0.0199
Mycobacterium ulcerans glutaminase 0.0566 0.1245 0.1243
Toxoplasma gondii ribonuclease HI protein 0.0316 0.0685 0.1252
Loa Loa (eye worm) melatonin receptor type 1A 0.0059 0.0107 0.0194
Plasmodium vivax bromodomain protein, putative 0.0084 0.0164 0.0299
Brugia malayi Importin beta-1 subunit 0.0031 0.0045 0.0083
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0109 0.0198
Echinococcus granulosus serotonin transporter 0.0241 0.0515 0.095
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0059 0.0107 0.0195
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0316 0.0685 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Brugia malayi reverse transcriptase 0.0027 0.0035 0.0065
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0102 0.0203 0.0372
Loa Loa (eye worm) hypothetical protein 0.0315 0.0681 0.1256
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0055 0.0776
Schistosoma mansoni hypothetical protein 0.0356 0.0773 0.1428
Echinococcus granulosus KRAB A domain containing protein 0.0027 0.0035 0.0061
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0018 0.0016 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0504 0.1106 0.6285
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0058 0.0294
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0018 0.0016 0.0015
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Echinococcus granulosus tm gpcr rhodopsin 0.0883 0.1958 0.3621
Trypanosoma brucei ribonuclease H1 0.0316 0.0685 0.1264
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.007 0.0691
Brugia malayi MH2 domain containing protein 0.0017 0.0013 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Brugia malayi Carboxylesterase family protein 0.0205 0.0435 0.0804
Echinococcus granulosus lysine specific histone demethylase 1A 0.0315 0.0681 0.1257
Brugia malayi Isocitrate dehydrogenase 0.2418 0.5403 1
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0042 0.0078
Treponema pallidum ribonuclease H (rnhA) 0.0316 0.0685 1
Brugia malayi Amidase family protein 0.0012 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Schistosoma mansoni transcription initiation factor tfiid 0.0084 0.0164 0.0299
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0041 0.0067 0.0946
Onchocerca volvulus 0.003 0.0043 0.0095
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.012 0.0244 0.3554
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0016 0.0025
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0029 0.0074
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0055 0.0057
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0241 0.0515 0.095
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0065 0.0067
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0016 0.0025
Onchocerca volvulus 0.0059 0.0107 0.0934
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0133 0.0274 0.0292
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0018 0.0016 0.0015
Entamoeba histolytica Ran family GTPase 0.0023 0.0026 0.0059
Trypanosoma brucei Bromodomain, putative 0.0084 0.0164 0.0299
Echinococcus multilocularis RNA directed DNA polymerase 0.0027 0.0035 0.0061
Onchocerca volvulus Neuropeptide F receptor homolog 0.0059 0.0107 0.0934
Brugia malayi Bromodomain containing protein 0.0084 0.0164 0.0303
Treponema pallidum fructose-bisphosphate aldolase 0.0289 0.0624 0.9104
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0624 0.3505
Schistosoma mansoni pyruvate kinase 0.0037 0.0058 0.0103
Brugia malayi MH2 domain containing protein 0.0017 0.0013 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0018 0.0016 0.0015
Schistosoma mansoni hypothetical protein 0.0059 0.0107 0.0195
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0059 0.0107 0.0195
Schistosoma mansoni lamin 0.003 0.0042 0.0074
Echinococcus granulosus histone acetyltransferase KAT2B 0.0127 0.0259 0.0476
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0624 0.3505
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Loa Loa (eye worm) hypothetical protein 0.0241 0.0515 0.095
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.0016 0.0025
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0018 0.0016 0.0014
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0065 0.0062
Echinococcus granulosus rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Brugia malayi Cytochrome P450 family protein 0.0027 0.0036 0.0066
Loa Loa (eye worm) RecQ helicase 0.0045 0.0075 0.0135
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0014
Echinococcus multilocularis neuropeptides capa receptor 0.0059 0.0107 0.0195
Schistosoma mansoni phd/f-box containing protein 0.0016 0.001 0.0014
Brugia malayi Cytochrome P450 family protein 0.004 0.0064 0.0118
Loa Loa (eye worm) hypothetical protein 0.0419 0.0915 0.1691
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0065 0.0067
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0043 0.0075
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0043 0.0075
Toxoplasma gondii thioredoxin reductase 0.0052 0.0093 0.0154
Schistosoma mansoni ap endonuclease 0.0021 0.0022 0.0036
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.0016 0.0025
Echinococcus multilocularis pyruvate kinase 0.0037 0.0058 0.0103
Brugia malayi Carboxylesterase family protein 0.1212 0.2696 0.499
Echinococcus granulosus biogenic amine 5HT receptor 0.0059 0.0107 0.0195
Schistosoma mansoni protein phosphatase 2C 0.0016 0.001 0.0014
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.0294 0.0634 0.1174
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0118 0.0214
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.0256 0.047
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0315 0.0681 0.1257
Echinococcus granulosus intermediate filament protein 0.003 0.0042 0.0074
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0059 0.0107 0.0195
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0371 0.0808 0.4567
Echinococcus granulosus Bromodomain containing protein 0.0084 0.0164 0.0299
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.0294 0.0634 0.117
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0076 0.0146 0.0266
Echinococcus multilocularis G protein coupled receptor 139 0.0059 0.0107 0.0195
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0035 0.0061
Loa Loa (eye worm) beta-lactamase 0.004 0.0065 0.0115
Schistosoma mansoni hypothetical protein 0.0333 0.0721 0.1332
Schistosoma mansoni ran 0.0023 0.0026 0.0045
Echinococcus granulosus expressed conserved protein 0.0093 0.0183 0.0335
Echinococcus granulosus neuropeptide Y receptor 0.0059 0.0107 0.0195
Schistosoma mansoni importin beta-1 0.0031 0.0045 0.0079
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0026 0.0044
Schistosoma mansoni neuropeptide receptor 0.0059 0.0107 0.0195
Onchocerca volvulus 0.0371 0.0808 1
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0035 0.0061
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0016 0.0025
Echinococcus multilocularis Niemann Pick C1 protein 0.0141 0.0292 0.0536
Mycobacterium tuberculosis Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.0294 0.0634 0.068
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0289 0.0624 0.7658
Echinococcus granulosus tm gpcr rhodopsin 0.0059 0.0107 0.0195
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0064 0.0102
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0059 0.0107 0.0199
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0065 0.0115
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0035 0.0065
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0133 0.0274 0.0292
Loa Loa (eye worm) hypothetical protein 0.003 0.0042 0.0073
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.0294 0.0634 0.3564
Echinococcus granulosus peregrin 0.0084 0.0164 0.0299
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0016 0.0012
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Echinococcus multilocularis rhodopsin orphan GPCR 0.0059 0.0107 0.0195
Mycobacterium tuberculosis Probable reductase 0.012 0.0244 0.026
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.0533 0.0982
Brugia malayi Pyruvate kinase, M2 isozyme 0.0037 0.0058 0.0107
Onchocerca volvulus 0.0059 0.0107 0.0934
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0018 0.0016 0.0014
Brugia malayi Serotonin receptor 0.0059 0.0107 0.0199
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0105 0.0191
Schistosoma mansoni smad1 5 8 and 0.0017 0.0013 0.002
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.02 0.0366
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0099 0.0197 0.2225
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.2418 0.5403 0.5812
Schistosoma mansoni opsin-like receptor 0.0059 0.0107 0.0195
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0624 0.3505
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0065 0.0115
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0205 0.0435 0.0465
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0065 0.0115
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Echinococcus multilocularis CREB binding protein 0.0084 0.0164 0.0299
Brugia malayi Pao retrotransposon peptidase family protein 0.0027 0.0035 0.0065
Onchocerca volvulus 0.0084 0.0164 0.1661
Brugia malayi Carboxylesterase family protein 0.1212 0.2696 0.499
Plasmodium vivax importin-beta 2, putative 0.0031 0.0045 0.0079
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0059 0.0107 0.0195
Brugia malayi Probable isocitrate dehydrogenase 0.0294 0.0634 0.1174
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0315 0.0681 0.1256
Loa Loa (eye worm) bromodomain containing protein 0.0084 0.0164 0.0299
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0035 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Trichomonas vaginalis bromodomain-containing protein, putative 0.0371 0.0808 0.4567
Onchocerca volvulus 0.0059 0.0107 0.0934
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0027 0.0035 0.0061
Loa Loa (eye worm) hypothetical protein 0.0041 0.0067 0.0119
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0036 0.0062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0059 0.0107 0.0195
Mycobacterium leprae Probable pyruvate kinase PykA 0.0037 0.0058 0.0819
Plasmodium vivax hypothetical protein, conserved 0.0315 0.0681 0.1256
Leishmania major hypothetical protein, conserved 0.0016 0.001 0.0014
Brugia malayi hypothetical protein 0.0059 0.0107 0.0199
Brugia malayi larval opioid receptor 0.0059 0.0107 0.0199
Echinococcus multilocularis serotonin transporter 0.0241 0.0515 0.095
Brugia malayi putative amidase 0.0012 0.0002 0.0004
Brugia malayi beta-lactamase family protein 0.004 0.0065 0.0119
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.0292 0.4268
Echinococcus multilocularis lamin 0.003 0.0042 0.0074
Trypanosoma brucei Bromodomain, putative 0.0084 0.0164 0.0299
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0105 0.0191
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0289 0.0624 0.7658
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0041 0.0067 0.0119
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0164 0.0852
Loa Loa (eye worm) TYRA-2 protein 0.0059 0.0107 0.0194
Echinococcus granulosus ribonuclease H1 0.0316 0.0685 0.1264
Schistosoma mansoni sodium/chloride dependent transporter 0.0041 0.0067 0.0119
Brugia malayi RNA, U transporter 1 0.0089 0.0174 0.0322
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0022 0.0035
Loa Loa (eye worm) hypothetical protein 0.0294 0.0634 0.117
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0035 0.0061
Onchocerca volvulus 0.0059 0.0107 0.0934
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0022 0.0021
Schistosoma mansoni adenoreceptor 0.0059 0.0107 0.0195
Mycobacterium tuberculosis Possible maturase 0.0027 0.0035 0.0035
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0084 0.0164 0.0299
Schistosoma mansoni hypothetical protein 0.0041 0.0067 0.0119
Leishmania major cytochrome p450-like protein 0.0027 0.0036 0.0061
Loa Loa (eye worm) hypothetical protein 0.0241 0.0515 0.095
Mycobacterium tuberculosis Conserved hypothetical protein 0.0315 0.0681 0.073
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0624 0.3505
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0022 0.004
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0058 0.0103
Leishmania major isocitrate dehydrogenase, putative 0.0294 0.0634 0.117
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.0256 0.0469
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.2418 0.5403 1
Leishmania major hypothetical protein, conserved 0.0027 0.0036 0.0062
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0036 0.0061
Brugia malayi reverse transcriptase 0.0027 0.0035 0.0065
Toxoplasma gondii isocitrate dehydrogenase 0.2418 0.5403 1
Schistosoma mansoni bromodomain containing protein 0.0086 0.0167 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0018 0.0016 0.0014
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.0093 0.0097
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0041 0.0067 0.0119
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0022 0.0283
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0205 0.0435 0.0465
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0059 0.0107 0.0195
Plasmodium falciparum transporter, putative 0.0041 0.0067 0.0119
Schistosoma mansoni patched 1 0.0042 0.007 0.0126
Echinococcus multilocularis sodium and chloride dependent glycine 0.0041 0.0067 0.0119
Entamoeba histolytica bromodomain-containing protein 0.0084 0.0164 0.1804
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.0438 0.0808
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0064 0.0115
Echinococcus granulosus fmrfamide receptor 0.0059 0.0107 0.0195
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0059 0.0107 0.0195
Loa Loa (eye worm) hypothetical protein 0.0059 0.0107 0.0194
Plasmodium falciparum pyruvate kinase 2 0.0019 0.0018 0.0028
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0076 0.0146 0.0266
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0333 0.0721 0.1332
Schistosoma mansoni cpg binding protein 0.003 0.0043 0.0076
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0022 0.0283
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0164 0.0852

Activities

Activity type Activity value Assay description Source Reference
Exp Inhib Constant (binding) = 2.53 Tested for inhibition constant against glycogen phosphorylase b ChEMBL. 8057302
Ki (binding) = 5.4 mM Inhibition of rabbit glycogen phosphorylase B enzyme ChEMBL. 9154968
Ki (binding) = 5.4 mM The compound was evaluated for the inhibition of glycogen phosphorylase ChEMBL. 10377222
Ki (binding) = 5.4 mM Inhibition of rabbit glycogen phosphorylase B enzyme ChEMBL. 9154968
lnKi (binding) = 2.53 Tested for inhibition constant against glycogen phosphorylase b ChEMBL. 8057302
Log Ki (binding) = 2.27 mM Inhibitory activity against rabbit muscle glycogen phosphorylase ChEMBL. 9406599
Log Ki (binding) = 2.27 mM Inhibitory activity against rabbit muscle glycogen phosphorylase ChEMBL. 9406599

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

4 literature references were collected for this gene.

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