Detailed information for compound 460341

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 437.594 | Formula: C26H31NO3S
  • H donors: 0 H acceptors: 3 LogP: 4.75 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1CC[C@@]2(C(=C1)CCN(C2)S(=O)(=O)c1ccc(cc1)C(C)(C)C)Cc1ccccc1
  • InChi: 1S/C26H31NO3S/c1-25(2,3)21-9-11-24(12-10-21)31(29,30)27-16-14-22-17-23(28)13-15-26(22,19-27)18-20-7-5-4-6-8-20/h4-12,17H,13-16,18-19H2,1-3H3/t26-/m1/s1
  • InChiKey: YGAPRLXEVVTMID-AREMUKBSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tm gpcr rhodopsin 0.026 0.0447 0.0456
Leishmania major beta tubulin 0.0161 0.0215 0.02
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.2766 0.6298 0.763
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.026 0.0447 0.0541
Echinococcus granulosus neuropeptide s receptor 0.026 0.0447 0.0456
Brugia malayi endoprotease bli-4 precursor 0.1669 0.3736 0.4527
Schistosoma mansoni site-1 peptidase (S08 family) 0.0077 0.0019 0.002
Echinococcus multilocularis g protein coupled receptor 0.026 0.0447 0.0456
Schistosoma mansoni tubulin subunit beta 0.0161 0.0215 0.0219
Trypanosoma cruzi hypothetical protein, conserved 0.087 0.1871 0.1894
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0088 0.0043 0.0053
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.4352 1 1
Echinococcus granulosus neuropeptide Y receptor 0.026 0.0447 0.0456
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Echinococcus multilocularis histone deacetylase 8 0.0275 0.0481 0.0491
Trichomonas vaginalis histone deacetylase, putative 0.0899 0.1938 0.1938
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Trypanosoma cruzi cdc2-related kinase 3 0.0088 0.0043 0.0025
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0557 0.114 0.1163
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.026 0.0447 0.0541
Schistosoma mansoni hypothetical protein 0.0194 0.0292 0.0298
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Schistosoma mansoni biogenic amine (dopamine) receptor 0.026 0.0447 0.0456
Loa Loa (eye worm) hypothetical protein 0.0417 0.0813 0.0985
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.1189 0.2614 0.3167
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0019 0.0019
Echinococcus multilocularis histone deacetylase 6 0.0349 0.0654 0.0667
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.026 0.0447 0.0456
Trichomonas vaginalis conserved hypothetical protein 0.087 0.1871 0.1871
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0101 0.0075 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.035 0.0656 0.0656
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0451 0.0892 0.0892
Schistosoma mansoni furin-1 (S08 family) 0.0787 0.1676 0.1711
Brugia malayi hypothetical protein 0.026 0.0447 0.0541
Schistosoma mansoni histamine h1 receptor 0.026 0.0447 0.0456
Giardia lamblia G2/mitotic-specific cyclin B 0.0151 0.0192 0.0475
Echinococcus granulosus histone deacetylase 3 0.0899 0.1938 0.1978
Schistosoma mansoni neuropeptide receptor 0.026 0.0447 0.0456
Echinococcus granulosus Tubulin beta 2C chain 0.0161 0.0215 0.0219
Plasmodium vivax tubulin beta chain, putative 0.0161 0.0215 0.0627
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.4265 0.9797 0.9797
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Plasmodium vivax histone deacetylase, putative 0.0275 0.0481 0.1482
Trichomonas vaginalis hypothetical protein 0.035 0.0656 0.0656
Schistosoma mansoni hypothetical protein 0.0107 0.0089 0.0091
Echinococcus granulosus neuropeptide receptor 0.026 0.0447 0.0456
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.4265 0.9797 0.9797
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Brugia malayi indoleamine 2,3-dioxygenase 0.0632 0.1316 0.1594
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.1189 0.2614 0.3167
Echinococcus granulosus somatostatin receptor 0.026 0.0447 0.0456
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.087 0.1871 0.1871
Echinococcus multilocularis serotonin receptor 0.026 0.0447 0.0456
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.026 0.0447 0.0456
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.087 0.1871 0.2391
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0451 0.0892 0.0892
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.2282 0.5167 0.5167
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.087 0.1871 0.2391
Schistosoma mansoni cyclin B 0.0151 0.0192 0.0196
Onchocerca volvulus 0.0417 0.0813 1
Onchocerca volvulus 0.0077 0.0019 0.0239
Echinococcus multilocularis histone deacetylase 3 0.0899 0.1938 0.1978
Echinococcus multilocularis histone deacetylase 6 0.0336 0.0623 0.0636
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.1896 0.4265 0.5168
Trichomonas vaginalis conserved hypothetical protein 0.3394 0.7765 0.7765
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.087 0.1871 0.191
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.1499 0.3338 1
Brugia malayi Protein kinase domain containing protein 0.0203 0.0313 0.0379
Toxoplasma gondii hypothetical protein 0.1412 0.3135 0.4023
Schistosoma mansoni tubulin subunit beta 0.0161 0.0215 0.0219
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.1427 0.3172 0.3238
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.4265 0.9797 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.4265 0.9797 0.9797
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.0447 0.0456
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.026 0.0447 0.0456
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.3604 0.8253 1
Echinococcus multilocularis 0.1319 0.2919 0.2979
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.026 0.0447 0.5491
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0899 0.1938 0.1938
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0451 0.0892 0.0892
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.087 0.1871 0.1871
Toxoplasma gondii hypothetical protein 0.3394 0.7765 1
Loa Loa (eye worm) histone deacetylase 7A 0.0336 0.0623 0.0754
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0019 0.0019
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.087 0.1871 0.191
Loa Loa (eye worm) histone deacetylase 0.0336 0.0623 0.0754
Schistosoma mansoni amine GPCR 0.026 0.0447 0.0456
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0959 0.2079 0.2122
Brugia malayi Cyclin, N-terminal domain containing protein 0.0151 0.0192 0.0233
Echinococcus granulosus peptide allatostatin:somatostatin 0.026 0.0447 0.0456
Leishmania major beta tubulin 0.0161 0.0215 0.02
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.1669 0.3736 0.3813
Schistosoma mansoni adenoreceptor 0.026 0.0447 0.0456
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Giardia lamblia Beta tubulin 0.0161 0.0215 0.0548
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.2742 0.6242 0.7563
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.4352 1 1
Echinococcus multilocularis G protein coupled receptor 139 0.0411 0.0798 0.0815
Trichomonas vaginalis conserved hypothetical protein 0.035 0.0656 0.0656
Echinococcus multilocularis neuropeptide receptor A26 0.026 0.0447 0.0456
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0151 0.0192 0.0177
Brugia malayi G-protein coupled receptor 0.026 0.0447 0.0541
Trypanosoma brucei histone deacetylase 3 0.0336 0.0623 0.0617
Trypanosoma cruzi hypothetical protein, conserved 0.087 0.1871 0.1894
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0632 0.1316 0.1343
Onchocerca volvulus 0.026 0.0447 0.5491
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0557 0.114 0.1163
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Trichomonas vaginalis retinoblastoma binding protein, putative 0.0073 0.001 0.001
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.0447 0.0456
Echinococcus granulosus beta tubulin 0.0161 0.0215 0.0219
Trichomonas vaginalis tubulin epsilon chain, putative 0.0161 0.0215 0.0215
Brugia malayi Protein kinase domain containing protein 0.0088 0.0043 0.0053
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.4265 0.9797 0.9797
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.026 0.0447 0.0456
Schistosoma mansoni peptide (allatostatin)-like receptor 0.026 0.0447 0.0456
Onchocerca volvulus 0.0107 0.0089 0.11
Echinococcus multilocularis neuropeptide receptor 0.0411 0.0798 0.0815
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.2766 0.6298 0.6428
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Brugia malayi neuroendocrine convertase 1 precursor 0.1311 0.2901 0.3514
Trichomonas vaginalis conserved hypothetical protein 0.035 0.0656 0.0656
Echinococcus granulosus tachykinin peptides receptor 99D 0.026 0.0447 0.0456
Echinococcus multilocularis Tubulin beta 2C chain 0.0161 0.0215 0.0219
Plasmodium vivax histone deacetylase, putative 0.0336 0.0623 0.1936
Schistosoma mansoni histone deacetylase hda2 0.0275 0.0481 0.0491
Schistosoma mansoni hypothetical protein 0.0106 0.0085 0.0087
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.0447 0.0456
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.1118 0.2449 0.25
Brugia malayi G protein-coupled receptor F59B2.13 0.026 0.0447 0.0541
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.133 0.2943 0.2991
Echinococcus multilocularis geminin 0.0194 0.0292 0.0298
Plasmodium falciparum phosphodiesterase delta, putative 0.087 0.1871 0.5943
Schistosoma mansoni hypothetical protein 0.0632 0.1316 0.1343
Echinococcus granulosus tm gpcr rhodopsin 0.026 0.0447 0.0456
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.0447 0.0456
Trypanosoma cruzi histone deacetylase, putative 0.0336 0.0623 0.0617
Schistosoma mansoni retinoblastoma binding protein 0.0073 0.001 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.0088 0.0043 0.0043
Schistosoma mansoni biogenic amine (5HT) receptor 0.026 0.0447 0.0456
Trypanosoma cruzi cdc2-related kinase 1 0.0088 0.0043 0.0025
Brugia malayi RE15519p 0.026 0.0447 0.0541
Trichomonas vaginalis tubulin, putative 0.0161 0.0215 0.0215
Echinococcus granulosus orexin receptor type 2 0.026 0.0447 0.0456
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.026 0.0447 0.0541
Echinococcus granulosus rhodopsin orphan GPCR 0.026 0.0447 0.0456
Echinococcus granulosus Tubulin beta 2C chain 0.0161 0.0215 0.0219
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.026 0.0447 0.0456
Loa Loa (eye worm) hypothetical protein 0.0087 0.0041 0.005
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Echinococcus granulosus histone deacetylase 7 0.0336 0.0623 0.0636
Trichomonas vaginalis conserved hypothetical protein 0.035 0.0656 0.0656
Schistosoma mansoni inhibitor of apoptosis protein 0.0107 0.0089 0.0091
Loa Loa (eye worm) TYRA-2 protein 0.026 0.0447 0.0541
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Toxoplasma gondii kringle domain-containing protein 0.0203 0.0313 0.0379
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Schistosoma mansoni hypothetical protein 0.026 0.0447 0.0456
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0161 0.0214 0.0219
Loa Loa (eye worm) hypothetical protein 0.0733 0.1551 0.188
Schistosoma mansoni biogenic amine receptor 0.026 0.0447 0.0456
Echinococcus multilocularis neuropeptide receptor 0.026 0.0447 0.0456
Trypanosoma brucei cAMP-specific phosphodiesterase 0.4265 0.9797 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.026 0.0447 0.0456
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.2853 0.6501 0.6501
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.026 0.0447 0.0456
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Plasmodium falciparum GAF domain-related protein, putative 0.1412 0.3135 1
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.1189 0.2614 0.2668
Toxoplasma gondii GAF domain-containing protein 0.1412 0.3135 0.4023
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0959 0.2079 0.2079
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0077 0.0019 0.0024
Brugia malayi Tubulin beta-1 chain 0.0161 0.0215 0.026
Loa Loa (eye worm) hypothetical protein 0.0074 0.0011 0.0014
Schistosoma mansoni opsin-like receptor 0.026 0.0447 0.0456
Echinococcus multilocularis Tubulin beta 2C chain 0.0161 0.0215 0.0219
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.2282 0.5167 0.5167
Echinococcus multilocularis biogenic amine (5HT) receptor 0.026 0.0447 0.0456
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Leishmania major beta tubulin 0.0161 0.0215 0.02
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Echinococcus granulosus epidermal growth factor receptor 0.0125 0.0131 0.0133
Brugia malayi hypothetical protein 0.026 0.0447 0.0541
Schistosoma mansoni hypothetical protein 0.0632 0.1316 0.1343
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Echinococcus granulosus 7TM GPCR rhodopsin 0.026 0.0447 0.0456
Schistosoma mansoni hypothetical protein 0.0203 0.0313 0.0319
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0899 0.1938 0.1938
Loa Loa (eye worm) hypothetical protein 0.0107 0.0089 0.0108
Trypanosoma brucei beta tubulin 0.0161 0.0215 0.02
Brugia malayi cell division control protein 2 homolog 0.0088 0.0043 0.0053
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Echinococcus multilocularis beta tubulin 0.0161 0.0215 0.0219
Echinococcus granulosus dnaJ subfamily B 0.249 0.5652 0.577
Echinococcus multilocularis neuropeptide s receptor 0.026 0.0447 0.0456
Echinococcus multilocularis neuroendocrine convertase 2 0.1161 0.2549 0.2602
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Echinococcus multilocularis dro:myosuppressin receptor 0.026 0.0447 0.0456
Entamoeba histolytica cyclin, putative 0.0151 0.0192 0.0785
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.026 0.0447 0.0456
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.4265 0.9797 1
Schistosoma mansoni tubulin subunit beta 0.0161 0.0215 0.0219
Schistosoma mansoni hypothetical protein 0.026 0.0447 0.0456
Trypanosoma brucei RNA helicase, putative 0.0106 0.0085 0.0068
Trypanosoma cruzi hypothetical protein, conserved 0.0203 0.0313 0.03
Trichomonas vaginalis cyclin B, putative 0.0151 0.0192 0.0192
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.087 0.1871 0.2391
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.216 0.4882 0.4983
Brugia malayi G protein-coupled receptor 0.026 0.0447 0.0541
Loa Loa (eye worm) hypothetical protein 0.1189 0.2614 0.3167
Trypanosoma cruzi histone deacetylase, putative 0.0336 0.0623 0.0617
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.133 0.2943 0.2991
Toxoplasma gondii histone deacetylase HDAC1 0.0336 0.0623 0.0779
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.026 0.0447 0.0456
Echinococcus multilocularis dnaJ subfamily B 0.249 0.5652 0.577
Schistosoma mansoni neuropeptide f receptor 76f 0.026 0.0447 0.0456
Brugia malayi Kringle domain containing protein 0.0203 0.0313 0.0379
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Echinococcus multilocularis orexin receptor type 2 0.026 0.0447 0.0456
Schistosoma mansoni biogenic amine (5HT) receptor 0.026 0.0447 0.0456
Loa Loa (eye worm) hypothetical protein 0.0318 0.0582 0.0705
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Leishmania major beta tubulin 0.0161 0.0215 0.02
Loa Loa (eye worm) neuropeptide F receptor 0.026 0.0447 0.0541
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Trichomonas vaginalis cyclin B, putative 0.0151 0.0192 0.0192
Schistosoma mansoni biogenic amine (dopamine) receptor 0.026 0.0447 0.0456
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.087 0.1871 0.2391
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.026 0.0447 0.0456
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0087 0.0042 0.0023
Echinococcus granulosus neuropeptide Y receptor 0.026 0.0447 0.0456
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Trichomonas vaginalis cyclins, putative 0.0103 0.008 0.008
Trichomonas vaginalis tubulin alpha chain, putative 0.0161 0.0215 0.0215
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.026 0.0447 0.0541
Toxoplasma gondii beta-1 tubulin, putative 0.0161 0.0215 0.0252
Loa Loa (eye worm) hypothetical protein 0.0899 0.1938 0.2348
Echinococcus multilocularis tubulin subunit beta 0.0161 0.0215 0.0219
Schistosoma mansoni growth hormone secretagogue receptor 0.026 0.0447 0.0456
Echinococcus multilocularis g protein coupled receptor 0.026 0.0447 0.0456
Trypanosoma cruzi histone deacetylase, putative 0.0336 0.0623 0.0617
Echinococcus multilocularis beta tubulin 0.0161 0.0215 0.0219
Echinococcus granulosus histone deacetylase 0.0336 0.0623 0.0636
Brugia malayi Matrixin family protein 0.0107 0.0088 0.0107
Echinococcus multilocularis neuropeptide FF receptor 2 0.2103 0.475 0.4849
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.4265 0.9797 1
Trypanosoma brucei UNC119 0.0115 0.0108 0.009
Echinococcus granulosus rhodopsin orphan GPCR 0.026 0.0447 0.0456
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Brugia malayi G-protein coupled receptor 0.026 0.0447 0.0541
Loa Loa (eye worm) tubulin beta-4 chain 0.0161 0.0215 0.026
Echinococcus multilocularis cyclin dependent kinase 0.0088 0.0043 0.0044
Trypanosoma brucei GAF domain/TIP41-like family, putative 0.0087 0.0042 0.0023
Loa Loa (eye worm) hypothetical protein 0.2742 0.6242 0.7563
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0088 0.0043 0.0053
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0374 0.0712 0.0712
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Onchocerca volvulus 0.0203 0.0313 0.3844
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0873 0.1878 0.2399
Onchocerca volvulus 0.026 0.0447 0.5491
Trypanosoma brucei hypothetical protein, conserved 0.087 0.1871 0.1894
Brugia malayi GnHR receptor homolog 0.026 0.0447 0.0541
Loa Loa (eye worm) neuropeptide F receptor 0.026 0.0447 0.0541
Trichomonas vaginalis conserved hypothetical protein 0.1412 0.3135 0.3135
Loa Loa (eye worm) histone deacetylase 1 0.0899 0.1938 0.2348
Loa Loa (eye worm) hypothetical protein 0.057 0.117 0.1417
Schistosoma mansoni tubulin subunit beta 0.0161 0.0215 0.0219
Echinococcus granulosus inhibitor of apoptosis protein 0.0107 0.0089 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0019 0.0019
Echinococcus multilocularis fmrfamide receptor 0.026 0.0447 0.0456
Schistosoma mansoni neuropeptide F-like receptor 0.026 0.0447 0.0456
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.087 0.1871 0.2267
Loa Loa (eye worm) endoprotease bli-4 0.1669 0.3736 0.4527
Brugia malayi Histone deacetylase family protein 0.0336 0.0623 0.0754
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.4265 0.9797 1
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.1427 0.3172 0.3238
Schistosoma mansoni hypothetical protein 0.035 0.0656 0.067
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.4265 0.9797 0.9797
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Loa Loa (eye worm) hypothetical protein 0.1669 0.3736 0.4527
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Schistosoma mansoni site-1 peptidase (S08 family) 0.0077 0.0019 0.002
Brugia malayi Trypsin family protein 0.0417 0.0813 0.0985
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1118 0.2449 0.3137
Leishmania major histone deacetylase, putative 0.0336 0.0623 0.0617
Loa Loa (eye worm) hypothetical protein 0.1427 0.3172 0.3843
Toxoplasma gondii histone deacetylase HDAC3 0.0899 0.1938 0.2477
Brugia malayi Cyclin, N-terminal domain containing protein 0.0151 0.0192 0.0233
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.087 0.1871 0.2391
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.1427 0.3172 0.3238
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.2853 0.6501 0.6629
Trypanosoma brucei cdc2-related kinase 3 0.0088 0.0043 0.0025
Trypanosoma cruzi cdc2-related kinase 3 0.0088 0.0043 0.0025
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.1118 0.2449 0.25
Trypanosoma cruzi histone deacetylase, putative 0.0275 0.0481 0.0472
Onchocerca volvulus 0.026 0.0447 0.5491
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.087 0.1871 0.5943
Giardia lamblia High cysteine membrane protein Group 2 0.0532 0.1082 0.3319
Schistosoma mansoni tubulin subunit beta 0.0161 0.0215 0.0219
Loa Loa (eye worm) hypothetical protein 0.0484 0.0969 0.1174
Plasmodium falciparum histone deacetylase 1 0.0899 0.1938 0.6158
Brugia malayi putative neuropeptide receptor 0.026 0.0447 0.0541
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.087 0.1871 0.191
Echinococcus multilocularis cyclin dependent kinase 1 0.0088 0.0043 0.0044
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.087 0.1871 0.1894
Plasmodium falciparum histone deacetylase 2 0.0336 0.0623 0.1936
Echinococcus multilocularis cyclin dependent kinase 1 0.0088 0.0043 0.0044
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.1427 0.3172 0.3238
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.087 0.1871 0.2391
Toxoplasma gondii subtilisin SUB12 0.0106 0.0087 0.0087
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.035 0.0656 0.0656
Echinococcus multilocularis Tubulin beta 2C chain 0.0161 0.0215 0.0219
Schistosoma mansoni hypothetical protein 0.0194 0.0292 0.0298
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.133 0.2943 0.2991
Echinococcus granulosus dro:myosuppressin receptor 0.026 0.0447 0.0456
Trichomonas vaginalis cyclin A, putative 0.0151 0.0192 0.0192
Brugia malayi histone deacetylase 11 0.0275 0.0481 0.0583
Echinococcus granulosus neuroendocrine convertase 2 0.1161 0.2549 0.2602
Trypanosoma cruzi UNC119 0.0115 0.0108 0.009
Toxoplasma gondii histone deacetylase HDAC4 0.0275 0.0481 0.0596
Brugia malayi beta-tubulin, identical 0.0161 0.0215 0.026
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0043 0.0044
Toxoplasma gondii histone deacetylase HDAC2 0.0899 0.1938 0.2477
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Loa Loa (eye worm) melatonin receptor type 1A 0.026 0.0447 0.0541
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.143 0.3178 0.4078
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0406 0.0788 0.0804
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.026 0.0447 0.0456
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.026 0.0447 0.0456
Loa Loa (eye worm) TK/EGFR protein kinase 0.0125 0.0131 0.0158
Trichomonas vaginalis tubulin beta chain, putative 0.0161 0.0215 0.0215
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0557 0.114 0.1381
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0088 0.0043 0.0025
Loa Loa (eye worm) hypothetical protein 0.0175 0.0246 0.0298
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Onchocerca volvulus 0.026 0.0447 0.5491
Brugia malayi hypothetical protein 0.026 0.0447 0.0541
Echinococcus multilocularis membrane bound transcription factor site 1 0.0077 0.0019 0.002
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0899 0.1938 0.1938
Entamoeba histolytica tubulin family protein 0.0161 0.0215 0.0905
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.4265 0.9797 1
Trichomonas vaginalis cyclins, putative 0.0151 0.0192 0.0192
Echinococcus granulosus cyclin dependent kinase 0.0088 0.0043 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.0447 0.0456
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0077 0.0019 0.0024
Onchocerca volvulus Matrix metalloproteinase homolog 0.0098 0.0068 0.0834
Echinococcus granulosus biogenic amine 5HT receptor 0.026 0.0447 0.0456
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2396 0.5434 0.5547
Trichomonas vaginalis histone deacetylase, putative 0.0899 0.1938 0.1938
Loa Loa (eye worm) PDE1B protein 0.2738 0.6233 0.7552
Brugia malayi ORL1-like opioid receptor 0.026 0.0447 0.0541
Leishmania major hypothetical protein, conserved 0.087 0.1871 0.1894
Echinococcus granulosus 7tm_1 domain containing protein 0.026 0.0447 0.0456
Brugia malayi follicle stimulating hormone receptor 0.026 0.0447 0.0541
Echinococcus multilocularis fmrfamide receptor 0.026 0.0447 0.0456
Echinococcus multilocularis cyclin B 0.0151 0.0192 0.0196
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Echinococcus granulosus neuropeptide receptor A26 0.026 0.0447 0.0456
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.087 0.1871 0.2391
Schistosoma mansoni amine GPCR 0.026 0.0447 0.0456
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.026 0.0447 0.0456
Brugia malayi histone deacetylase 3 (HD3) 0.0899 0.1938 0.2348
Echinococcus granulosus histone deacetylase 8 0.0275 0.0481 0.0491
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.0447 0.0456
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.087 0.1871 0.2391
Brugia malayi hypothetical protein 0.026 0.0447 0.0541
Leishmania major beta tubulin 0.0161 0.0215 0.02
Trypanosoma cruzi beta tubulin, putative 0.0161 0.0215 0.02
Trypanosoma brucei cdc2-related kinase 1 0.0088 0.0043 0.0025
Echinococcus multilocularis serotonin receptor 0.026 0.0447 0.0456
Echinococcus granulosus neuropeptides capa receptor 0.026 0.0447 0.0456
Giardia lamblia Histone deacetylase 0.0899 0.1938 0.6056
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0959 0.2079 0.2122
Echinococcus multilocularis g protein coupled receptor 0.026 0.0447 0.0456
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.087 0.1871 0.1871
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.2766 0.6298 0.6428
Trypanosoma brucei beta tubulin 0.0161 0.0215 0.02
Brugia malayi Histone deacetylase 1 0.0899 0.1938 0.2348
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0632 0.1316 0.1594
Echinococcus multilocularis Tubulin beta 2C chain 0.0161 0.0215 0.0219
Giardia lamblia hypothetical protein 0.087 0.1871 0.5842
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0451 0.0892 0.0892
Schistosoma mansoni neuropeptide receptor 0.0411 0.0798 0.0815
Echinococcus granulosus beta tubulin 0.0161 0.0215 0.0219
Trichomonas vaginalis histone deacetylase, putative 0.0899 0.1938 0.1938
Loa Loa (eye worm) matrixin family protein 0.0107 0.0088 0.0107
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.026 0.0447 0.0456
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.133 0.2943 0.9385
Giardia lamblia Furin precursor putative serine protease 0.0374 0.0712 0.2136
Brugia malayi histone deacetylase 1 (HD1) 0.0899 0.1938 0.2348
Schistosoma mansoni opsin-like receptor 0.026 0.0447 0.0456
Loa Loa (eye worm) hypothetical protein 0.0088 0.0045 0.0054
Echinococcus granulosus membrane bound transcription factor site 1 0.0077 0.0019 0.002
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.133 0.2943 0.3004
Plasmodium vivax histone deacetylase 2, putative 0.0336 0.0623 0.1936
Loa Loa (eye worm) tubulin beta chain 0.0161 0.0215 0.026
Schistosoma mansoni histone deacetylase 1 2 3 0.0275 0.0481 0.0491
Toxoplasma gondii beta tubulin 0.0161 0.0215 0.0252
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.087 0.1871 0.1871
Onchocerca volvulus 0.026 0.0447 0.5491
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.026 0.0447 0.0456
Loa Loa (eye worm) BEN-1 protein 0.0161 0.0215 0.026
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.026 0.0447 0.0456
Schistosoma mansoni biogenic amine receptor 0.026 0.0447 0.0456
Schistosoma mansoni histone deacetylase 0.0899 0.1938 0.1978
Brugia malayi Histone deacetylase family protein 0.0336 0.0623 0.0754
Echinococcus granulosus sex peptide receptor 0.026 0.0447 0.0456
Trichomonas vaginalis conserved hypothetical protein 0.035 0.0656 0.0656
Echinococcus granulosus Tubulin beta 2C chain 0.0161 0.0215 0.0219
Loa Loa (eye worm) matrixin family protein 0.0098 0.0068 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.3394 0.7765 0.7765
Echinococcus granulosus Tubulin beta 2C chain 0.0161 0.0215 0.0219
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.1427 0.3172 0.3238
Schistosoma mansoni myosin xvIII 0.026 0.0447 0.0456
Onchocerca volvulus 0.026 0.0447 0.5491
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Leishmania major beta tubulin 0.0161 0.0215 0.02
Echinococcus multilocularis cyclin dependent kinase 5 0.0088 0.0043 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0043 0.0044
Brugia malayi sulfakinin receptor protein 0.026 0.0447 0.0541
Brugia malayi larval opioid receptor 0.026 0.0447 0.0541
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.0447 0.0456
Echinococcus granulosus neuropeptides capa receptor 0.0459 0.0912 0.093
Onchocerca volvulus Matrilysin homolog 0.0098 0.0068 0.0834
Loa Loa (eye worm) hypothetical protein 0.0073 0.001 0.0013
Echinococcus granulosus rhodopsin orphan GPCR 0.026 0.0447 0.0456
Leishmania major cAMP-specific phosphodiesterase, putative 0.087 0.1871 0.1894
Schistosoma mansoni amine GPCR 0.026 0.0447 0.0456
Brugia malayi hypothetical protein 0.026 0.0447 0.0541
Echinococcus multilocularis allatostatin A receptor 0.026 0.0447 0.0456
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.4265 0.9797 0.9797
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.087 0.1871 0.2391
Echinococcus multilocularis neuropeptide Y receptor 0.026 0.0447 0.0456
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.087 0.1871 0.1894
Trichomonas vaginalis cyclin B, putative 0.0151 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.087 0.1871 0.1871
Leishmania major beta tubulin 0.0161 0.0215 0.02
Echinococcus multilocularis Furin 1 0.0451 0.0892 0.0911
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0451 0.0892 0.0911
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0088 0.0043 0.0053
Mycobacterium ulcerans putative regulatory protein 0.1412 0.3135 0.9388
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0451 0.0892 0.0892
Echinococcus multilocularis histone deacetylase 1 0.0899 0.1938 0.1978
Loa Loa (eye worm) hypothetical protein 0.2103 0.475 0.5756
Brugia malayi Serotonin/octopamine receptor family protein 7 0.026 0.0447 0.0541
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.026 0.0447 0.0541
Echinococcus granulosus tubulin beta 1 chain 0.0161 0.0215 0.0219
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.026 0.0447 0.0456
Onchocerca volvulus 0.0151 0.0192 0.2361
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0161 0.0214 0.0219
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0019 0.0019
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.087 0.1871 0.1871
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.133 0.2943 0.3004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.0447 0.0456
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.087 0.1871 0.2391
Brugia malayi AKH receptor 0.026 0.0447 0.0541
Echinococcus granulosus allatostatin A receptor 0.026 0.0447 0.0456
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Schistosoma mansoni hypothetical protein 0.026 0.0447 0.0456
Schistosoma mansoni neuropeptide F-like receptor 0.026 0.0447 0.0456
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Onchocerca volvulus 0.026 0.0447 0.5491
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Leishmania major beta tubulin 0.0161 0.0215 0.02
Onchocerca volvulus 0.026 0.0447 0.5491
Loa Loa (eye worm) tubulin beta-2A chain 0.0161 0.0215 0.026
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.087 0.1871 0.5943
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.087 0.1871 0.191
Plasmodium vivax phosphodiesterase gamma, putative 0.087 0.1871 0.5943
Plasmodium falciparum cGMP-specific phosphodiesterase 0.087 0.1871 0.5943
Loa Loa (eye worm) tubulin beta-1 chain 0.0161 0.0215 0.026
Leishmania major cyclin 0.0151 0.0192 0.0177
Loa Loa (eye worm) hypothetical protein 0.0151 0.0192 0.0233
Brugia malayi Hypothetical WD-repeat protein F21H12.1 in chromosome II 0.0073 0.001 0.0013
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.026 0.0447 0.0456
Echinococcus multilocularis histone deacetylase 0.0336 0.0623 0.0636
Brugia malayi Tachykinin-like peptides receptor 99D 0.2103 0.475 0.5756
Schistosoma mansoni biogenic amine receptor 0.026 0.0447 0.0456
Echinococcus granulosus histone deacetylase 6 0.0336 0.0623 0.0636
Trypanosoma cruzi hypothetical protein, conserved 0.087 0.1871 0.1894
Leishmania major beta tubulin 0.0161 0.0215 0.02
Echinococcus multilocularis tubulin beta 1 chain 0.0161 0.0215 0.0219
Giardia lamblia Hypothetical protein 0.0115 0.0108 0.0205
Trichomonas vaginalis cyclins, putative 0.0151 0.0192 0.0192
Onchocerca volvulus 0.026 0.0447 0.5491
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Loa Loa (eye worm) histone deacetylase 11 0.0275 0.0481 0.0583
Echinococcus granulosus hypothetical protein 0.026 0.0447 0.0456
Mycobacterium leprae conserved hypothetical protein 0.1412 0.3135 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.026 0.0447 0.0456
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0557 0.114 0.1381
Echinococcus granulosus g protein coupled receptor 0.026 0.0447 0.0456
Echinococcus multilocularis G-protein coupled receptor, putative 0.026 0.0447 0.0456
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0077 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0318 0.0582 0.0705
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.026 0.0447 0.0456
Trichomonas vaginalis histone deacetylase, putative 0.0899 0.1938 0.1938
Leishmania major beta tubulin 0.0161 0.0215 0.02
Onchocerca volvulus Deterin homolog 0.0107 0.0089 0.11
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.133 0.2943 0.2991
Brugia malayi proprotein convertase 2 0.1161 0.2549 0.3088
Toxoplasma gondii beta-tubulin, putative 0.0161 0.0215 0.0252
Trypanosoma cruzi UNC119 0.0115 0.0108 0.009
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0087 0.0042 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.0447 0.0456
Loa Loa (eye worm) hypothetical protein 0.2733 0.6221 0.7538
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.2738 0.6233 0.7552
Trypanosoma cruzi CYC2-like cyclin, putative 0.0151 0.0192 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.087 0.1871 0.1871
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0107 0.0089 0.0091
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.087 0.1871 0.2391
Echinococcus granulosus tm gpcr rhodopsin 0.2396 0.5434 0.5547
Trypanosoma cruzi cyclin 6, putative 0.0151 0.0192 0.0177
Plasmodium falciparum cysteine repeat modular protein 1 0.0203 0.0313 0.0941
Trichomonas vaginalis cyclins, putative 0.0151 0.0192 0.0192
Schistosoma mansoni neuropeptide receptor 0.026 0.0447 0.0456
Entamoeba histolytica histone deacetylase, putative 0.0899 0.1938 1
Brugia malayi Furin-like cysteine rich region family protein 0.0125 0.0131 0.0158
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Echinococcus granulosus biogenic amine 5HT receptor 0.026 0.0447 0.0456
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.0632 0.1316 0.1343
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Loa Loa (eye worm) subtilase 0.0077 0.0019 0.0024
Toxoplasma gondii histone deacetylase HDAC5 0.0275 0.0481 0.0596
Leishmania major beta tubulin 0.0161 0.0215 0.02
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.1412 0.3135 0.9388
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Plasmodium vivax hypothetical protein, conserved 0.1412 0.3135 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.026 0.0447 0.0456
Brugia malayi neuropeptide F receptor 0.026 0.0447 0.0541
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0019 0.0019
Echinococcus granulosus fmrfamide receptor 0.026 0.0447 0.0456
Echinococcus granulosus serotonin receptor 0.026 0.0447 0.0456
Schistosoma mansoni neuropeptide receptor 0.026 0.0447 0.0456
Brugia malayi neuropeptide F receptor 0.026 0.0447 0.0541
Leishmania major beta tubulin 0.0161 0.0215 0.02
Echinococcus granulosus histone deacetylase 6 0.0349 0.0654 0.0667
Echinococcus granulosus cyclin dependent kinase 1 0.0088 0.0043 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.4352 1 1
Giardia lamblia Hypothetical protein 0.087 0.1871 0.5842
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.4265 0.9797 0.9797
Schistosoma mansoni hypothetical protein 0.249 0.5652 0.577
Trichomonas vaginalis conserved hypothetical protein 0.035 0.0656 0.0656
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Echinococcus granulosus histone deacetylase 6 0.0336 0.0623 0.0636
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.2742 0.6242 0.6371
Trichomonas vaginalis retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase, putative 0.057 0.117 0.117
Plasmodium falciparum histone deacetylase, putative 0.0336 0.0623 0.1936
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.2282 0.5167 0.5167
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Loa Loa (eye worm) follicle stimulating hormone receptor 0.026 0.0447 0.0541
Echinococcus granulosus histone deacetylase 1 0.0899 0.1938 0.1978
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.0447 0.0456
Trypanosoma cruzi cdc2-related kinase 1 0.0088 0.0043 0.0025
Schistosoma mansoni hypothetical protein 0.026 0.0447 0.0456
Trypanosoma brucei beta tubulin 0.0161 0.0215 0.02
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0088 0.0043 0.0044
Loa Loa (eye worm) hypothetical protein 0.0077 0.0019 0.0024
Echinococcus granulosus g protein coupled receptor 0.026 0.0447 0.0456
Brugia malayi Serotonin receptor 0.026 0.0447 0.0541
Echinococcus granulosus rhodopsin orphan GPCR 0.026 0.0447 0.0456
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Onchocerca volvulus 0.026 0.0447 0.5491
Brugia malayi gonadotropin-releasing hormone receptor 2 0.026 0.0447 0.0541
Echinococcus multilocularis g-protein coupled receptor 0.026 0.0447 0.0456
Mycobacterium ulcerans putative regulatory protein 0.1412 0.3135 0.9388
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.087 0.1871 0.1894
Echinococcus multilocularis epidermal growth factor receptor 0.0125 0.0131 0.0133
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.026 0.0447 0.0456
Schistosoma mansoni amine GPCR 0.026 0.0447 0.0456
Loa Loa (eye worm) TK/ROR protein kinase 0.0203 0.0313 0.0379
Brugia malayi Subtilase family protein 0.0077 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Schistosoma mansoni retinal rod rhodopsin-sensitive cgmp 3'5'-cyclic phosphodiesterase 0.057 0.117 0.1194
Onchocerca volvulus 0.026 0.0447 0.5491
Schistosoma mansoni tyrosine kinase 0.0125 0.0131 0.0133
Echinococcus multilocularis histone deacetylase 7 0.0336 0.0623 0.0636
Echinococcus multilocularis neuropeptides capa receptor 0.026 0.0447 0.0456
Onchocerca volvulus 0.026 0.0447 0.5491
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Trichomonas vaginalis histone deacetylase, putative 0.0899 0.1938 0.1938
Leishmania major beta tubulin 0.0161 0.0215 0.02
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0107 0.0089 0.0108
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.026 0.0447 0.0456
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.0447 0.0456
Echinococcus granulosus tubulin beta 4A class IVa 0.0161 0.0215 0.0219
Schistosoma mansoni histone deacetylase hda2 0.0349 0.0654 0.0667
Leishmania major histone deacetylase, putative 0.0899 0.1938 0.1962
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0101 0.0075 0.0075
Brugia malayi putative neuropeptide receptor NPR1 0.026 0.0447 0.0541
Echinococcus granulosus rhodopsin orphan GPCR 0.026 0.0447 0.0456
Plasmodium falciparum phosphodiesterase gamma, putative 0.087 0.1871 0.5943
Brugia malayi Dopamine receptor protein 1 0.026 0.0447 0.0541
Trypanosoma brucei beta tubulin 0.0161 0.0215 0.02
Schistosoma mansoni histone deacetylase 0.0899 0.1938 0.1978
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0203 0.0313 0.0941
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.0447 0.0456
Leishmania major beta tubulin 0.0161 0.0215 0.02
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.087 0.1871 0.2391
Brugia malayi celfurPC protein 0.1319 0.2919 0.3537
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.4265 0.9797 0.9797
Leishmania major beta tubulin 0.0161 0.0215 0.02
Loa Loa (eye worm) hypothetical protein 0.0417 0.0813 0.0985
Trichomonas vaginalis cyclin B, putative 0.0151 0.0192 0.0192
Brugia malayi hypothetical protein 0.026 0.0447 0.0541
Loa Loa (eye worm) hypothetical protein 0.0318 0.0582 0.0705
Leishmania major beta tubulin 0.0161 0.0215 0.02
Leishmania major hypothetical protein, conserved 0.0115 0.0108 0.009
Onchocerca volvulus 0.026 0.0447 0.5491
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0077 0.0019 0.002
Trichomonas vaginalis conserved hypothetical protein 0.3394 0.7765 0.7765
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Trichomonas vaginalis tubulin epsilon chain, putative 0.0161 0.0215 0.0215
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.0447 0.0456
Trypanosoma cruzi histone deacetylase, putative 0.0275 0.0481 0.0472
Trypanosoma cruzi hypothetical protein, conserved 0.087 0.1871 0.1894
Trichomonas vaginalis CMGC family protein kinase 0.0088 0.0043 0.0043
Leishmania major histone deacetylase, putative 0.0899 0.1938 0.1962
Onchocerca volvulus 0.026 0.0447 0.5491
Echinococcus granulosus neuropeptide receptor 0.0411 0.0798 0.0815
Trypanosoma cruzi histone deacetylase 1, putative 0.0899 0.1938 0.1962
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Schistosoma mansoni alpha-1 adrenergic receptor 0.026 0.0447 0.0456
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0417 0.0813 0.083
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.1499 0.3338 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0161 0.0215 0.0215
Brugia malayi hypothetical protein 0.0115 0.0108 0.013
Loa Loa (eye worm) histone deacetylase 3 0.0899 0.1938 0.2348
Brugia malayi hypothetical protein 0.026 0.0447 0.0541
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.026 0.0447 0.0456
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.216 0.4882 0.4983
Brugia malayi hypothetical protein 0.026 0.0447 0.0541
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.4265 0.9797 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0087 0.0042 0.0068
Trichomonas vaginalis CMGC family protein kinase 0.0088 0.0043 0.0043
Echinococcus multilocularis inhibitor of apoptosis protein 0.0107 0.0089 0.0091
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0451 0.0892 0.0892
Trichomonas vaginalis conserved hypothetical protein 0.035 0.0656 0.0656
Brugia malayi Serotonin receptor 0.026 0.0447 0.0541
Schistosoma mansoni tubulin subunit beta 0.0161 0.0215 0.0219
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Trichomonas vaginalis conserved hypothetical protein 0.035 0.0656 0.0656
Trypanosoma cruzi histone deacetylase 1, putative 0.0899 0.1938 0.1962
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0077 0.0019 0.002
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.2738 0.6233 0.6362
Schistosoma mansoni opsin-like receptor 0.026 0.0447 0.0456
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.2853 0.6501 0.6501
Trypanosoma brucei histone deacetylase 2 0.0275 0.0481 0.0472
Plasmodium vivax histone deacetylase 1, putative 0.0899 0.1938 0.6158
Echinococcus granulosus rhodopsin orphan GPCR 0.026 0.0447 0.0456
Echinococcus granulosus g-protein coupled receptor 0.026 0.0447 0.0456
Trichomonas vaginalis histone deacetylase, putative 0.0899 0.1938 0.1938
Leishmania major beta tubulin 0.0161 0.0215 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.001 0.001
Onchocerca volvulus 0.0357 0.0672 0.8258
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0107 0.0089 0.0108
Echinococcus granulosus neuropeptide FF receptor 2 0.2103 0.475 0.4849
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.026 0.0447 0.0456
Entamoeba histolytica tubulin family protein 0.0161 0.0215 0.0905
Trypanosoma cruzi hypothetical protein, conserved 0.087 0.1871 0.1894
Trichomonas vaginalis conserved hypothetical protein 0.035 0.0656 0.0656
Echinococcus multilocularis Tubulin beta 2C chain 0.0161 0.0215 0.0219
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.133 0.2943 0.3775
Leishmania major hypothetical protein, conserved 0.0203 0.0313 0.03
Loa Loa (eye worm) hypothetical protein 0.3604 0.8253 1
Brugia malayi hypothetical protein 0.057 0.117 0.1417
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.1118 0.2449 0.7798
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0957 0.2074 0.2074
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Brugia malayi Dopamine receptor protein 2 0.026 0.0447 0.0541
Trichomonas vaginalis conserved hypothetical protein 0.035 0.0656 0.0656
Leishmania major hypothetical protein, conserved 0.0087 0.0042 0.0023
Giardia lamblia Beta tubulin 0.0161 0.0215 0.0548
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.026 0.0447 0.0541
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0959 0.2079 0.2079
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.2738 0.6233 0.6362
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.4265 0.9797 0.9797
Echinococcus granulosus furin 0.1669 0.3736 0.3813
Trichomonas vaginalis cyclins, putative 0.0151 0.0192 0.0192
Trypanosoma brucei mitotic cyclin 6 0.0151 0.0192 0.0177
Loa Loa (eye worm) hypothetical protein 0.0275 0.0481 0.0583
Brugia malayi Dopamine receptor 0.026 0.0447 0.0541
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.2738 0.6233 0.6362
Schistosoma mansoni amine GPCR 0.045 0.089 0.0908
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.026 0.0447 0.0541
Leishmania major histone deacetylase, putative 0.0336 0.0623 0.0617
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.1427 0.3172 1
Brugia malayi hypothetical protein 0.026 0.0447 0.0541
Trypanosoma brucei histone deacetylase 4 0.0336 0.0623 0.0617
Echinococcus multilocularis neuropeptides capa receptor 0.0459 0.0912 0.093
Schistosoma mansoni histone deacetylase 4 5 0.0336 0.0623 0.0636
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0107 0.0089 0.0091
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.026 0.0447 0.0456
Echinococcus multilocularis histone deacetylase 6 0.0336 0.0623 0.0636
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Loa Loa (eye worm) hypothetical protein 0.0151 0.0192 0.0233
Loa Loa (eye worm) hypothetical protein 0.0203 0.0313 0.0379
Echinococcus granulosus cyclin dependent kinase 5 0.0088 0.0043 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.026 0.0447 0.0456
Echinococcus multilocularis sex peptide receptor 0.026 0.0447 0.0456
Plasmodium falciparum tubulin beta chain 0.0161 0.0215 0.0627
Onchocerca volvulus 0.026 0.0447 0.5491
Brugia malayi Melatonin receptor type 1A 0.026 0.0447 0.0541
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0417 0.0813 0.083
Echinococcus granulosus g protein coupled receptor 0.026 0.0447 0.0456
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.087 0.1871 0.191
Echinococcus granulosus Furin 1 0.0451 0.0892 0.0911
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.087 0.1871 0.1871
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0088 0.0043 0.0031
Onchocerca volvulus Neuropeptide F receptor homolog 0.026 0.0447 0.5491
Echinococcus multilocularis tachykinin peptides receptor 99D 0.026 0.0447 0.0456
Schistosoma mansoni biogenic amine (dopamine) receptor 0.026 0.0447 0.0456
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.087 0.1871 0.5943
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0374 0.0712 0.0712
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Echinococcus multilocularis tissue type plasminogen activator 0.0203 0.0313 0.0319
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Echinococcus granulosus tissue type plasminogen activator 0.0203 0.0313 0.0319
Trypanosoma cruzi hypothetical protein, conserved 0.087 0.1871 0.1894
Echinococcus granulosus G protein coupled receptor 139 0.026 0.0447 0.0456
Loa Loa (eye worm) G-protein coupled receptor 0.026 0.0447 0.0541
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.1118 0.2449 0.25
Trichomonas vaginalis conserved hypothetical protein 0.035 0.0656 0.0656
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.0447 0.0456
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.087 0.1871 0.1894
Brugia malayi hypothetical protein 0.026 0.0447 0.0541
Loa Loa (eye worm) hypothetical protein 0.0115 0.0108 0.013
Plasmodium vivax protein kinase Crk2 0.0088 0.0043 0.0077
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.087 0.1871 0.2391
Leishmania major hypothetical protein, conserved 0.087 0.1871 0.1894
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0107 0.0089 0.0091
Echinococcus multilocularis neuropeptide Y receptor 0.026 0.0447 0.0456
Trypanosoma brucei cAMP-specific phosphodiesterase 0.4265 0.9797 1
Giardia lamblia Beta tubulin 0.0161 0.0215 0.0548
Echinococcus granulosus geminin 0.0194 0.0292 0.0298
Schistosoma mansoni histone deacetylase 4 5 0.0336 0.0623 0.0636
Loa Loa (eye worm) proprotein convertase 2 0.0451 0.0892 0.1081
Onchocerca volvulus 0.026 0.0447 0.5491
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.087 0.1871 0.1894
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.133 0.2943 0.3775
Loa Loa (eye worm) hypothetical protein 0.0107 0.0089 0.0108
Loa Loa (eye worm) beta-tubulin 0.0161 0.0215 0.026
Echinococcus multilocularis somatostatin receptor 0.026 0.0447 0.0456
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.0447 0.0456
Onchocerca volvulus Histone deacetylase 10 homolog 0.0275 0.0481 0.5916
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0088 0.0043 0.0025
Echinococcus granulosus tubulin subunit beta 0.0161 0.0215 0.0219
Onchocerca volvulus 0.026 0.0447 0.5491
Echinococcus granulosus cyclin B 0.0151 0.0192 0.0196
Echinococcus multilocularis rhodopsin orphan GPCR 0.026 0.0447 0.0456
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Loa Loa (eye worm) BEN-1 protein 0.0161 0.0215 0.026
Echinococcus multilocularis wd40 repeat 0.0073 0.001 0.0011
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0077 0.0019 0.0019
Trypanosoma cruzi cyclin, putative 0.0151 0.0192 0.0177
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.4265 0.9797 0.9797
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0161 0.0215 0.0219
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.087 0.1871 0.1871
Leishmania major beta tubulin 0.0161 0.0215 0.02
Echinococcus granulosus rhodopsin orphan GPCR 0.026 0.0447 0.0456
Echinococcus granulosus thyrotropin releasing hormone receptor 0.026 0.0447 0.0456
Trypanosoma brucei histone deacetylase 1 0.0899 0.1938 0.1962
Trypanosoma brucei histone deacetylase, putative 0.0336 0.0623 0.0617
Loa Loa (eye worm) G-protein coupled receptor 0.026 0.0447 0.0541
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0957 0.2074 0.2074
Echinococcus granulosus Tubulin beta 2C chain 0.0161 0.0215 0.0219
Echinococcus granulosus wd40 repeat 0.0073 0.001 0.0011
Trypanosoma cruzi cyclin, putative 0.0151 0.0192 0.0177
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Plasmodium falciparum protein kinase 5 0.0088 0.0043 0.0077
Loa Loa (eye worm) hypothetical protein 0.026 0.0447 0.0541
Toxoplasma gondii hypothetical protein 0.1412 0.3135 0.4023
Plasmodium falciparum cGMP-specific phosphodiesterase 0.087 0.1871 0.5943

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) > 10000 nM Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in recombinant baculovirus ChEMBL. 17822897
Ki (binding) > 10000 nM Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in recombinant baculovirus ChEMBL. 17822897

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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