Detailed information for compound 46116

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 457.298 | Formula: C16H7F8N3O2S
  • H donors: 2 H acceptors: 4 LogP: 5.06 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1c(O)c2cccc(c2nc1C(C(F)(F)F)(F)F)C(F)(F)F)Nc1nccs1
  • InChi: 1S/C16H7F8N3O2S/c17-14(18,16(22,23)24)11-8(12(29)27-13-25-4-5-30-13)10(28)6-2-1-3-7(9(6)26-11)15(19,20)21/h1-5H,(H,26,28)(H,25,27,29)
  • InChiKey: AYMVXSSIMLOUQH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0051 0.0073 0.0535
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0024 0.0099
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0088 0.0148 0.0554
Mycobacterium ulcerans acyl-CoA synthetase 0.0088 0.0148 0.0545
Loa Loa (eye worm) hypothetical protein 0.013 0.0234 0.172
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0084 0.0139 0.0523
Echinococcus granulosus carbonyl reductase 1 0.002 0.0011 0.004
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0012 0.0094
Echinococcus granulosus microsomal glutathione S transferase 3 0.0231 0.0438 0.2006
Brugia malayi steroid hormone receptor 0.0051 0.0073 0.0271
Echinococcus multilocularis retinol dehydrogenase 13 0.002 0.0011 0.0009
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Leishmania major 4-coumarate:coa ligase-like protein 0.0299 0.0576 0.2159
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0041 0.0052 0.0488
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0016 0.0049
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0088 0.0148 0.054
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0073
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0023 0.0016 0.0044
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0027 0.01
Loa Loa (eye worm) oxidoreductase 0.002 0.0011 0.0076
Toxoplasma gondii propionate-CoA ligase 0.0088 0.0148 0.0545
Loa Loa (eye worm) hypothetical protein 0.0299 0.0576 0.4253
Brugia malayi ecdysone receptor 0.0024 0.0019 0.0066
Leishmania major short chain dehydrogenase, putative 0.002 0.0011 0.0042
Echinococcus multilocularis geminin 0.0516 0.1018 0.1016
Brugia malayi Importin beta-1 subunit 0.0028 0.0027 0.0096
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Echinococcus granulosus lamin 0.0029 0.0028 0.0118
Echinococcus granulosus snurportin 1 0.0298 0.0575 0.2636
Trichomonas vaginalis helicase, putative 0.0019 0.0009 0.0062
Brugia malayi MAP kinase sur-1 0.0053 0.0077 0.0286
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0077 0.028
Leishmania major acetyl-CoA synthetase, putative 0.0088 0.0148 0.0554
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0023 0.0016 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0051 0.0073 0.0271
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0211 0.0398 0.148
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0041 0.0052 0.0488
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0041 0.0052 0.0488
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0028 0.0027 0.0103
Trypanosoma cruzi metacaspase 5, putative 0.0055 0.0082 0.0306
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0191 0.0358 0.1329
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0103 0.0385
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.002 0.0011 0.0042
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0114 0.0202 0.1953
Plasmodium vivax patched family protein, putative 0.0019 0.0008 0.0021
Brugia malayi photoreceptor-specific nuclear receptor 0.0051 0.0073 0.0271
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.0026 0.0099
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0519 0.1023 0.4696
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0163 0.0301 0.2222
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0051 0.0073 0.0275
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0062
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.002 0.0011 0.0027
Echinococcus multilocularis muscleblind protein 1 0.0165 0.0304 0.0302
Schistosoma mansoni nuclear receptor 0.0024 0.0019 0.007
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0299 0.0576 0.2126
Mycobacterium ulcerans oxidoreductase 0.002 0.0011 0.0033
Mycobacterium leprae putative cytochrome p450 0.0023 0.0016 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0015 0.0055
Mycobacterium ulcerans acyl-CoA synthetase 0.0088 0.0148 0.0545
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0011 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0082 0.0775
Echinococcus granulosus survival motor neuron protein 1 0.0485 0.0955 0.4385
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0077 0.0289
Onchocerca volvulus 0.0019 0.0008 0.0033
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0102 0.0178 0.0652
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0055 0.0082 0.0775
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0082
Schistosoma mansoni cpg binding protein 0.0091 0.0155 0.0583
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.002 0.0011 0.0042
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.004 0.0052 0.0184
Brugia malayi protein C24B5.3 0.0019 0.0008 0.0027
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0009 0.0062
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0041 0.0052 0.0187
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0021 0.0012 0.0036
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0379
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0211 0.0398 0.148
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0157 0.0289 0.1076
Loa Loa (eye worm) runx1 0.0058 0.0087 0.0635
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Giardia lamblia Reductase, putative 0.002 0.0011 0.0141
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Giardia lamblia hypothetical protein 0.0022 0.0015 0.0196
Leishmania major hypothetical protein, conserved 0.0025 0.002 0.0075
Echinococcus granulosus histone acetyltransferase KAT2B 0.0289 0.0557 0.2551
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0082
Echinococcus multilocularis histidyl tRNA synthetase 0.0024 0.0019 0.0016
Loa Loa (eye worm) hypothetical protein 0.0459 0.0902 0.667
Loa Loa (eye worm) PDE1B protein 0.0022 0.0015 0.0101
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0024 0.0022
Mycobacterium leprae conserved hypothetical protein 0.0057 0.0086 0.0281
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0004 0.0001
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0041 0.0175
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Brugia malayi acetyltransferase, GNAT family protein 0.03 0.0578 0.2166
Loa Loa (eye worm) oxidoreductase 0.0088 0.0148 0.1086
Entamoeba histolytica hypothetical protein 0.0218 0.0412 0.4011
Brugia malayi AMP-binding enzyme family protein 0.0088 0.0148 0.0551
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0034 0.0038 0.0274
Loa Loa (eye worm) hypothetical protein 0.0223 0.0423 0.312
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Onchocerca volvulus 0.002 0.0011 0.0064
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.004 0.0052 0.048
Schistosoma mansoni hypothetical protein 0.002 0.001 0.0039
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0022 0.0015 0.0119
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0218 0.0819
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.013 0.0234 0.1063
Plasmodium falciparum phosphodiesterase delta, putative 0.0022 0.0015 0.0046
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0299 0.0576 0.2148
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0023 0.0016 0.0058
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0016 0.0058
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0088 0.0148 0.0545
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0131
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0051 0.0073 0.0535
Trichomonas vaginalis inositol monophosphatase, putative 0.0114 0.0202 0.1953
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0022 0.0015 0.0055
Brugia malayi conserved hypotetical protein 0.0024 0.0019 0.0066
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0025 0.0101
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0061 0.0058
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0079 0.0131 0.1255
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0011 0.0042
Brugia malayi hypothetical protein 0.0019 0.0008 0.0027
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0024 0.0019 0.0062
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0005 0.0022
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.002 0.0011 0.0033
Brugia malayi hypothetical protein 0.0459 0.0902 0.3381
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0079 0.0131 0.1255
Leishmania major metacaspase, putative 0.0055 0.0082 0.0306
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0028 0.0117
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0098 0.0369
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0051 0.0073 0.0326
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0031 0.0113
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0088 0.0148 0.0554
Leishmania major 3-keto-dihydrosphingosine reductase 0.002 0.0011 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0062
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0055 0.0082 0.0775
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0041 0.0038
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0084 0.0139 0.0523
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0009 0.0062
Loa Loa (eye worm) PHD-finger family protein 0.002 0.001 0.007
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.0074 0.0278
Mycobacterium ulcerans acyl-CoA synthetase 0.0088 0.0148 0.0545
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0005 0.0008
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0076
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0218 0.081
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0011 0.0033
Echinococcus granulosus nibrin 0.0021 0.0012 0.0044
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0027 0.0024
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.002 0.0011 0.0027
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.0014
Brugia malayi Bromodomain containing protein 0.0044 0.006 0.0221
Schistosoma mansoni topbp1 0.0021 0.0012 0.0045
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0055 0.0082 0.0775
Schistosoma mansoni bromodomain containing protein 0.0016 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0223 0.0423 0.312
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.002 0.0011 0.0042
Brugia malayi hypothetical protein 0.0019 0.0008 0.0027
Schistosoma mansoni steroid dehydrogenase 0.002 0.0011 0.0042
Echinococcus granulosus Threonyl tRNA synthetase C 0.004 0.0052 0.0226
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0022 0.0015 0.0055
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0016 0.0108
Trypanosoma brucei seryl-tRNA synthetase 0.0016 0.0003 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0011 0.0042
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0022 0.0015 0.0055
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0017 0.0015
Giardia lamblia Replication factor C, subunit 1 0.0021 0.0012 0.0155
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0016 0.0058
Plasmodium vivax dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.1329 0.2667 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0082
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0073 0.0071
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0022 0.0015 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0103 0.0385
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0097 0.0166 0.1604
Onchocerca volvulus 0.002 0.0011 0.0064
Brugia malayi hypothetical protein 0.0027 0.0025 0.0088
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.002 0.0011 0.0042
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0005 0.0018
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0519 0.1023 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0051 0.0073 0.0071
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0088 0.0148 0.0554
Brugia malayi Myosin head containing protein 0.0019 0.0008 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0703 0.1397 0.1395
Brugia malayi Sars1 protein 0.0016 0.0003 0.0005
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.0092 0.1435
Loa Loa (eye worm) hypothetical protein 0.0084 0.0139 0.1024
Echinococcus granulosus sterol regulatory element binding protein 0.0133 0.024 0.1095
Entamoeba histolytica hypothetical protein 0.0218 0.0412 0.4011
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0202 0.0757
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0114 0.0202 0.0748
Toxoplasma gondii hypothetical protein 0.0057 0.0086 0.0313
Plasmodium vivax histone acetyltransferase GCN5, putative 0.009 0.0152 0.0562
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.004 0.0052 0.0193
Schistosoma mansoni carbonyl reductase 0.002 0.0011 0.0042
Loa Loa (eye worm) oxidoreductase 0.002 0.0011 0.0076
Plasmodium vivax SET domain protein, putative 0.0067 0.0106 0.0388
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.0026 0.0099
Echinococcus multilocularis Niemann Pick C1 protein 0.0444 0.0871 0.0869
Loa Loa (eye worm) hypothetical protein 0.0028 0.0027 0.0192
Plasmodium vivax sentrin-specific protease 2, putative 0.0041 0.0052 0.0187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0103 0.0385
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0011 0.0009
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0088 0.0148 0.054
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0092 0.0873
Chlamydia trachomatis histidine--tRNA ligase 0.0024 0.0019 0.0391
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0022 0.0015 0.0119
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0026 0.0234
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.0092 0.0344
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0103 0.0385
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0011 0.0027
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0004 0.0006
Schistosoma mansoni hypothetical protein 0.0801 0.1597 0.5987
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0022 0.0015 0.0055
Onchocerca volvulus Protein patched homolog 0.0019 0.0008 0.0033
Brugia malayi Protein kinase domain containing protein 0.0034 0.0039 0.0143
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0011 0.0086
Brugia malayi RNA, U transporter 1 0.0079 0.0131 0.0488
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.002 0.0011 0.0086
Loa Loa (eye worm) patched family protein 0.0019 0.0008 0.0052
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0019 0.0137
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0051 0.0073 0.0275
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Onchocerca volvulus Protein ultraspiracle homolog 0.0051 0.0073 0.0674
Echinococcus granulosus dnaJ subfamily B 0.0801 0.1597 0.7337
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.004 0.0052 0.0193
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0041 0.0052 0.0488
Loa Loa (eye worm) hypothetical protein 0.0281 0.0539 0.3984
Brugia malayi protein C24B5.3 0.0019 0.0008 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0082 0.0775
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.002 0.0011 0.0009
Schistosoma mansoni survival motor neuron protein 0.0099 0.0171 0.0641
Echinococcus granulosus netrin receptor unc 5 0.0034 0.0038 0.0164
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0011 0.0042
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0073 0.0271
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0103 0.0385
Entamoeba histolytica hypothetical protein 0.002 0.0011 0.0086
Schistosoma mansoni zinc finger protein 0.0024 0.0019 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.0017 0.0015
Mycobacterium ulcerans putative regulatory protein 0.0079 0.0131 0.0481
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0004 0.0022
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0011 0.0042
Brugia malayi Inositol-1 0.0114 0.0202 0.0753
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.004 0.0052 0.0152
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.002 0.0011 0.0033
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0023 0.0016 0.0049
Loa Loa (eye worm) oxidoreductase 0.002 0.0011 0.0076
Onchocerca volvulus 0.0159 0.0293 0.2828
Loa Loa (eye worm) hypothetical protein 0.0053 0.0078 0.0572
Brugia malayi nuclear hormone receptor 0.0024 0.0019 0.0066
Trypanosoma cruzi FHA domain containing protein, putative 0.0021 0.0012 0.0045
Schistosoma mansoni hypothetical protein 0.013 0.0234 0.0876
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Loa Loa (eye worm) hypothetical protein 0.004 0.0052 0.0373
Onchocerca volvulus 0.0041 0.0052 0.0467
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0022 0.0015 0.0046
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0079 0.0131 0.059
Schistosoma mansoni prolyl-tRNA synthetase 0.013 0.0235 0.0879
Plasmodium vivax threonine--tRNA ligase, putative 0.004 0.0052 0.0184
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0131
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0022 0.0015 0.0055
Brugia malayi hypothetical protein 0.002 0.0011 0.0038
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0088 0.0148 0.054
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0077 0.0732
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0023 0.0016 0.0049
Brugia malayi bHLH-PAS transcription factor 0.0079 0.0131 0.0486
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.002 0.0011 0.0086
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0022 0.0015 0.0056
Onchocerca volvulus 0.002 0.0011 0.0064
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0019 0.0066
Loa Loa (eye worm) hypothetical protein 0.041 0.0803 0.5934
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0182 0.034 0.1273
Leishmania major pteridine reductase 1 0.002 0.0011 0.0042
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0088 0.0148 0.054
Schistosoma mansoni hypothetical protein 0.0281 0.0539 0.2023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0103 0.0385
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.002 0.0011 0.0076
Brugia malayi Pre-SET motif family protein 0.0067 0.0106 0.0393
Brugia malayi PAS domain containing protein 0.0107 0.0187 0.0698
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0011 0.0039
Mycobacterium ulcerans carveol-like dehydrogenase 0.002 0.0011 0.0033
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0519 0.1023 0.4696
Echinococcus multilocularis snurportin 1 0.0298 0.0575 0.0573
Loa Loa (eye worm) patched family protein 0.0019 0.0008 0.0052
Entamoeba histolytica acyl-coA synthetase, putative 0.0299 0.0576 0.5619
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0011 0.0032
Echinococcus multilocularis prolyl tRNA synthetase, mitochondrial 0.013 0.0235 0.0232
Trichomonas vaginalis antibiotic synthetase, putative 0.0088 0.0148 0.1424
Leishmania major cytochrome p450-like protein 0.0023 0.0016 0.0058
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.004 0.0052 0.0193
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.002 0.0011 0.0027
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0024 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0624 0.1236 0.9142
Brugia malayi latrophilin 2 splice variant baaae 0.0281 0.0539 0.202
Loa Loa (eye worm) hypothetical protein 0.0051 0.0073 0.0535
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0011 0.0027
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0077 0.0289
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0009 0.0062
Schistosoma mansoni single-minded 0.0107 0.0187 0.0702
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0011 0.0027
Onchocerca volvulus 0.0099 0.0171 0.1631
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0052 0.0488
Leishmania major cathepsin L-like protease 0.0065 0.0103 0.0385
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0041 0.0052 0.0192
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0019 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0012 0.0045
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0079 0.0131 0.049
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0519 0.1023 0.3836
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0016 0.0108
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.002 0.0011 0.0042
Schistosoma mansoni retinoic acid receptor RXR 0.0051 0.0073 0.0275
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0015 0.0119
Onchocerca volvulus 0.002 0.0011 0.0064
Plasmodium falciparum GAF domain-related protein, putative 0.0057 0.0086 0.0313
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0077 0.0075
Loa Loa (eye worm) oxidoreductase 0.002 0.0011 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0073 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Onchocerca volvulus 0.002 0.0011 0.0064
Toxoplasma gondii patched family protein 0.0019 0.0008 0.0021
Onchocerca volvulus 0.0019 0.0008 0.0033
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0011 0.0033
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0519 0.1023 1
Schistosoma mansoni DNA ligase IV 0.0021 0.0012 0.0045
Onchocerca volvulus 0.0088 0.0148 0.1405
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.0041
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.004 0.0052 0.048
Schistosoma mansoni lipoxygenase 0.0121 0.0215 0.0807
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.0092 0.0329
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0011 0.0033
Brugia malayi AMP-binding enzyme family protein 0.0088 0.0148 0.0551
Brugia malayi AMP-binding enzyme family protein 0.0299 0.0576 0.2156
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0076
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.002 0.0011 0.0033
Loa Loa (eye worm) hypothetical protein 0.0051 0.0073 0.0535
Trypanosoma brucei histidyl-tRNA synthetase 0.0024 0.0019 0.0071
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.004 0.0052 0.0193
Brugia malayi Doublecortin family protein 0.002 0.0011 0.0037
Mycobacterium tuberculosis Possible ketoacyl reductase 0.002 0.0011 0.0027
Brugia malayi RNA binding protein 0.0063 0.0098 0.0365
Loa Loa (eye worm) Ulp1 protease 0.0041 0.0052 0.0379
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0191 0.0358 0.1635
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0206 0.0388 0.1773
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0098 0.0369
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0028 0.0027 0.0103
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0202 0.0757
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Loa Loa (eye worm) hypothetical protein 0.0051 0.0073 0.0535
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0061 0.0228
Schistosoma mansoni zinc finger protein 0.0031 0.0033 0.0124
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0073 0.0271
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0025 0.0092
Loa Loa (eye worm) hypothetical protein 0.0223 0.0423 0.312
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0004 0.0007
Toxoplasma gondii hypothetical protein 0.0057 0.0086 0.0313
Echinococcus multilocularis oxidoreductase 0.002 0.0011 0.0009
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Echinococcus multilocularis caspase 2 0.0055 0.0082 0.0079
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0004 0.0015
Echinococcus multilocularis caspase 0.0206 0.0388 0.0385
Echinococcus multilocularis dnaJ subfamily B 0.0801 0.1597 0.1595
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0098 0.072
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0079 0.0131 0.049
Trypanosoma cruzi metacaspase, putative 0.0055 0.0082 0.0306
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.0092 0.0344
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0098 0.0369
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0023 0.0016 0.0058
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0088 0.0148 0.0514
Onchocerca volvulus 0.002 0.0011 0.0064
Mycobacterium ulcerans dehydrogenase 0.002 0.0011 0.0033
Schistosoma mansoni seryl-tRNA synthetase 0.0016 0.0003 0.0009
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Brugia malayi Patched related family protein 10 0.0019 0.0008 0.0027
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.004 0.0052 0.0189
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0218 0.0993
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0022 0.0015 0.0051
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0041 0.0052 0.0192
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.1329 0.2667 1
Onchocerca volvulus 0.0459 0.0902 0.8815
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0088 0.0148 0.0545
Mycobacterium tuberculosis Probable dehydrogenase 0.002 0.0011 0.0027
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0011 0.004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0061 0.0228
Mycobacterium ulcerans putative regulatory protein 0.0057 0.0086 0.0313
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0011 0.0008
Schistosoma mansoni seryl-tRNA synthetase 0.0016 0.0003 0.0009
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0077 0.0289
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.002 0.0066
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0025 0.0088
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0041 0.0052 0.0488
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0005 0.0018
Echinococcus multilocularis neuropeptide receptor A26 0.0493 0.097 0.0968
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.004 0.0052 0.0193
Mycobacterium ulcerans acyl-CoA synthetase 0.0088 0.0148 0.0545
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.004 0.0052 0.0152
Echinococcus multilocularis expressed conserved protein 0.0141 0.0257 0.0254
Onchocerca volvulus Cell death protein 3 homolog 0.0055 0.0082 0.0755
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0073 0.0071
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0028 0.0027 0.0103
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0055 0.0082 0.0297
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0131
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0004 0.0001
Plasmodium vivax acetyl-CoA synthetase, putative 0.0088 0.0148 0.0545
Brugia malayi hypoxia-induced factor 1 0.0331 0.0642 0.2406
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0086 0.0817
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0023 0.0016 0.0044
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0019 0.0075
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0009 0.0062
Echinococcus multilocularis cpg binding protein 0.0091 0.0155 0.0153
Loa Loa (eye worm) DR-78 0.0024 0.0019 0.0131
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0088 0.0148 0.0514
Loa Loa (eye worm) threonyl-tRNA synthetase 0.004 0.0052 0.0373
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0055 0.0082 0.0775
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0011 0.0042
Mycobacterium ulcerans hypothetical protein 0.0299 0.0576 0.2152
Brugia malayi nuclear receptor RXR 0.0027 0.0025 0.0088
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.0092 0.041
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0022 0.0015 0.0055
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0011 0.0033
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0022 0.0015 0.0012
Schistosoma mansoni hypothetical protein 0.013 0.0234 0.0876
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0519 0.1023 1
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0012 0.0094
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0098 0.0369
Brugia malayi PHD-finger family protein 0.0036 0.0044 0.0159
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0022 0.0015 0.0055
Leishmania major hypothetical protein, conserved 0.0022 0.0015 0.0055
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0114 0.0202 0.0748
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0082 0.0775
Echinococcus granulosus sentrin specific protease 1 0.0041 0.0052 0.0229
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0076
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0022 0.0015 0.0046
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0022 0.0015 0.0055
Echinococcus multilocularis cysteine protease 0.0017 0.0005 0.0002
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0003 0.0004
Echinococcus multilocularis GPCR, family 2 0.013 0.0234 0.0231
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0028 0.0199
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0004 0.0015
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0028 0.0026 0.0024
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0079 0.0131 0.1255
Loa Loa (eye worm) hypothetical protein 0.0051 0.0073 0.0535
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0022
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0218 0.081
Brugia malayi Patched related family protein 4 0.0019 0.0008 0.0027
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0051 0.0073 0.0326
Echinococcus granulosus aryl hydrocarbon receptor 0.0028 0.0026 0.011
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0011 0.0042
Loa Loa (eye worm) dehydrogenase 0.002 0.0011 0.0076
Mycobacterium ulcerans acyl-CoA synthetase 0.0088 0.0148 0.0545
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.009 0.0152 0.1467
Brugia malayi glycyl-tRNA synthetase 0.004 0.0052 0.0189
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.002 0.0011 0.0042
Echinococcus granulosus ecdysone induced protein 78C 0.0051 0.0073 0.0326
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0191 0.0358 0.1342
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0016 0.006
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.004 0.0052 0.0193
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0519 0.1023 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0218 0.0412 0.0409
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0023 0.0016 0.0049
Giardia lamblia Hypothetical protein 0.002 0.0011 0.0141
Echinococcus multilocularis lamin dm0 0.0029 0.0028 0.0026
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.0092 0.067
Echinococcus multilocularis ecdysone induced protein 78C 0.0051 0.0073 0.0071
Plasmodium falciparum histidine--tRNA ligase, putative 0.0024 0.0019 0.0062
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0023 0.0016 0.0044
Brugia malayi AMP-binding enzyme family protein 0.0299 0.0576 0.2156
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.002 0.0011 0.0042
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.002 0.0011 0.0027
Onchocerca volvulus 0.0079 0.0131 0.1237
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0187
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.002 0.0011 0.004
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.1007 0.2014 0.7552
Echinococcus multilocularis protein dispatched 1 0.0152 0.0279 0.0276
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0067 0.0106 0.0397
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.002 0.0011 0.0042
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0223 0.0423 0.312
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0023 0.0016 0.0058
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0005 0.0002
Schistosoma mansoni threonyl-tRNA synthetase 0.0024 0.0019 0.0071
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.004 0.0052 0.0179
Loa Loa (eye worm) hypothetical protein 0.0155 0.0284 0.209
Trypanosoma cruzi oxidoreductase-like protein, putative 0.002 0.0011 0.0042
Loa Loa (eye worm) hypothetical protein 0.0051 0.0073 0.0535
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Schistosoma mansoni hypothetical protein 0.0099 0.0171 0.0641
Echinococcus multilocularis muscleblind protein 0.0165 0.0304 0.0302
Echinococcus multilocularis thyroid hormone receptor alpha 0.0051 0.0073 0.0071
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0005 0.0014
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0022 0.0015 0.0051
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0097 0.0166 0.1604
Schistosoma mansoni threonyl-tRNA synthetase 0.0016 0.0003 0.0009
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0024 0.0019 0.0062
Echinococcus multilocularis conserved hypothetical protein 0.002 0.0011 0.0009
Giardia lamblia Glycyl-tRNA synthetase 0.004 0.0052 0.0789
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0034 0.0038 0.0164
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0011 0.0009
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0055 0.0082 0.0775
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0027 0.01
Plasmodium vivax hypothetical protein, conserved 0.0055 0.0082 0.0297
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.1329 0.2667 1
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0011 0.0009
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0005 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Loa Loa (eye worm) glycyl-tRNA synthetase 0.004 0.0052 0.0373
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.0014
Onchocerca volvulus 0.0019 0.0008 0.0033
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0018
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0022 0.0015 0.0056
Echinococcus granulosus expressed conserved protein 0.0292 0.0562 0.2576
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0057 0.0086 0.0308
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0097 0.0166 0.0623
Giardia lamblia Fructose-bisphosphate aldolase 0.0322 0.0624 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0005 0.0027
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.007 0.0112 0.0109
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0191 0.0358 0.1334
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0077 0.0289
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.002 0.0011 0.0064
Brugia malayi hypothetical protein 0.0024 0.0019 0.0066
Plasmodium falciparum proline--tRNA ligase, putative 0.013 0.0235 0.0871
Brugia malayi hypothetical protein 0.0025 0.002 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0051 0.0073 0.0271
Echinococcus granulosus Protein patched homolog 1 0.0133 0.024 0.1095
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0011 0.0033
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0055 0.0082 0.0775
Brugia malayi AMP-binding enzyme family protein 0.0299 0.0576 0.2156
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0102 0.0178 0.0626
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0315 0.061 0.2288
Onchocerca volvulus 0.002 0.0011 0.0061
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.004 0.0052 0.0184
Leishmania major histidyl-tRNA synthetase, putative 0.0024 0.0019 0.0071
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0011 0.0033
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0021 0.0012 0.0094
Schistosoma mansoni hypothetical protein 0.0054 0.0079 0.0295
Echinococcus granulosus carbonyl reductase 1 0.002 0.0011 0.004
Leishmania major protein kinase, putative 0.0028 0.0027 0.0103
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0015 0.0055
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.002 0.0011 0.0042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.0624 0.6087
Treponema pallidum glycyl-tRNA synthetase 0.0024 0.0019 0.0264
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0088 0.0148 0.0145
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0011 0.0009
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0379
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0015 0.0119
Plasmodium falciparum metacaspase 1 0.0055 0.0082 0.0297
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0051 0.0073 0.0271
Toxoplasma gondii hypothetical protein 0.0019 0.0008 0.0021
Mycobacterium tuberculosis Probable dihydroorotate dehydrogenase PyrD 0.1329 0.2667 1
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0155 0.0284 0.106
Echinococcus multilocularis zinc finger protein 0.0031 0.0033 0.0031
Brugia malayi hypothetical protein 0.0021 0.0012 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0005 0.0022
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0041 0.0052 0.0196
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0299 0.0576 0.2152
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0057 0.0086 0.0313
Onchocerca volvulus 0.0024 0.0019 0.0137
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0079 0.0131 0.1255
Echinococcus granulosus cpg binding protein 0.0091 0.0155 0.0704
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Trypanosoma cruzi short-chain dehydrogenase, putative 0.002 0.0011 0.0042
Loa Loa (eye worm) hypothetical protein 0.0359 0.0699 0.5164
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0019 0.0016
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0088 0.0148 0.0545
Echinococcus multilocularis sentrin specific protease 1 0.0041 0.0052 0.005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0023 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0086 0.0817
Treponema pallidum threonyl-tRNA synthetase 0.004 0.0052 0.0789
Echinococcus granulosus caspase 8 0.0055 0.0082 0.0364
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0088 0.0148 0.0545
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.013 0.0234 0.1063
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0022
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0079 0.0131 0.1255
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0067 0.0106 0.0388
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0023 0.0016 0.0044
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0023 0.0016 0.0058
Toxoplasma gondii oxidoreductase, putative 0.002 0.0011 0.0033
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0079 0.0131 0.049
Loa Loa (eye worm) hypoxia-induced factor 1 0.0331 0.0642 0.4746
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0011 0.0042
Toxoplasma gondii MAPEG family protein 0.0231 0.0438 0.1636
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0051 0.0073 0.0535
Echinococcus multilocularis sentrin specific protease 7 0.0182 0.0339 0.0337
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0022
Loa Loa (eye worm) RNA binding protein 0.0063 0.0098 0.072
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0098 0.0369
Echinococcus granulosus microtubule associated protein 2 0.0669 0.1327 0.6095
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0022 0.0015 0.0119
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0016 0.0108
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0022 0.0015 0.0055
Brugia malayi Cytochrome P450 family protein 0.0064 0.0101 0.0374
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0519 0.1023 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0055 0.0082 0.0297
Loa Loa (eye worm) hypothetical protein 0.0051 0.0073 0.0535
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0223 0.0423 0.1572
Trichomonas vaginalis Sentrin-specific protease, putative 0.0097 0.0166 0.1604
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0041 0.0052 0.0488
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0148 0.054
Chlamydia trachomatis deubiquitinase/deneddylase Dub2 0.0041 0.0052 0.1185
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0077 0.0289
Leishmania major acetyl-CoA synthetase, putative 0.0088 0.0148 0.0554
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0218 0.081
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0131
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.0017 0.0069
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.004 0.0052 0.048
Echinococcus granulosus caspase 2 0.0055 0.0082 0.0364
Schistosoma mansoni hypothetical protein 0.0128 0.0231 0.0865
Plasmodium falciparum dihydroorotate dehydrogenase 0.1329 0.2667 1
Chlamydia trachomatis proline--tRNA ligase 0.0155 0.0284 0.6689
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0079 0.0131 0.1255
Plasmodium falciparum lipid/sterol:H+ symporter 0.0019 0.0008 0.0021
Echinococcus multilocularis sentrin specific protease 8 0.0097 0.0166 0.0164
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0051 0.0073 0.0326
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0011 0.0027
Mycobacterium ulcerans acyl-CoA synthetase 0.0299 0.0576 0.2152
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0073 0.0275
Entamoeba histolytica acyl-CoA synthetase, putative 0.0299 0.0576 0.5619
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0028 0.0026 0.011
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0088 0.0148 0.0669
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0062
Brugia malayi seryl-tRNA synthetase, mitochondrial precursor, putative 0.0016 0.0003 0.0005
Loa Loa (eye worm) bromodomain containing protein 0.0024 0.0019 0.0136
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0025 0.0022
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0079 0.0131 0.1255
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0299 0.0576 0.2148
Brugia malayi hypothetical protein 0.0016 0.0002 0.0005
Toxoplasma gondii anticodon binding domain-containing protein 0.0024 0.0019 0.0062
Echinococcus granulosus steroid dehydrogenase 0.002 0.0011 0.004
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.0014
Echinococcus multilocularis cysteine protease 0.0017 0.0005 0.0002
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0018
Schistosoma mansoni caspase-7 (C14 family) 0.0206 0.0388 0.1454
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0211 0.0398 0.148
Plasmodium falciparum proline--tRNA ligase 0.004 0.0052 0.0184
Treponema pallidum fructose-bisphosphate aldolase 0.0322 0.0624 1
Onchocerca volvulus 0.0029 0.0028 0.0229
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0103 0.0385
Mycobacterium leprae Probable dihydroorotate dehydrogenase PyrD 0.1329 0.2667 1
Echinococcus granulosus zinc finger protein 0.0031 0.0033 0.014
Schistosoma mansoni nuclear receptor 0.0024 0.0019 0.007
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0211 0.0398 0.148
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0098 0.072
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0022 0.0015 0.0056
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.002 0.0011 0.0009
Echinococcus multilocularis Ankyrin 0.0034 0.0038 0.0036
Echinococcus granulosus nuclear factor of activated T cells 5 0.0329 0.0637 0.2919
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.1329 0.2667 1
Schistosoma mansoni cellular tumor antigen P53 0.0159 0.0293 0.1098
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0011 0.0042
Echinococcus multilocularis neuropeptide s receptor 0.0493 0.097 0.0968
Schistosoma mansoni dihydroorotate dehydrogenase 0.1329 0.2667 1
Plasmodium falciparum threonine--tRNA ligase 0.004 0.0052 0.0184
Loa Loa (eye worm) hypothetical protein 0.0165 0.0304 0.2242
Plasmodium vivax hypothetical protein, conserved 0.002 0.0011 0.0033
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0182 0.0339 0.33
Echinococcus granulosus sentrin specific protease 8 0.0097 0.0166 0.0753
Echinococcus multilocularis 0.0023 0.0016 0.0013
Leishmania major hypothetical protein, conserved 0.002 0.0011 0.0042
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0131
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0076
Brugia malayi topoisomerase 0.0021 0.0012 0.0041
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.006 0.0091 0.0342
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0191 0.0358 0.1339
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0011 0.0042
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0004 0.0011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.0092 0.0344
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0062
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0191 0.0358 0.1334
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0011 0.0086
Brugia malayi ecdysteroid receptor 0.0051 0.0073 0.0271
Loa Loa (eye worm) patched family protein 0.0019 0.0008 0.0052
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0011 0.0033
Brugia malayi Latrophilin receptor protein 2 0.013 0.0234 0.0872
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0011 0.0033
Brugia malayi hypothetical protein 0.0019 0.0008 0.0027
Trichomonas vaginalis guanylate cyclase, putative 0.0028 0.0026 0.0234
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Plasmodium vivax sentrin-specific protease 1, putative 0.0041 0.0052 0.0187
Echinococcus multilocularis expressed conserved protein 0.0292 0.0562 0.056
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0456 0.0896 0.6619
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0015 0.0119
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0022 0.0015 0.0055
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0023 0.0016 0.0044
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0088 0.0148 0.0554
Brugia malayi AMP-binding enzyme family protein 0.0088 0.0148 0.0551
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0023 0.0016 0.0049
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0088 0.0148 0.0545
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0005 0.0002
Schistosoma mansoni steroid hormone receptor ad4bp 0.0051 0.0073 0.0275
Schistosoma mansoni steroid dehydrogenase 0.002 0.0011 0.0042
Toxoplasma gondii hypothetical protein 0.0057 0.0086 0.0313
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0202 0.0757
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0077 0.0289
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0004 0.0015
Schistosoma mansoni short-chain dehydrogenase/reductase 0.002 0.0011 0.0042
Schistosoma mansoni inositol monophosphatase 0.0114 0.0202 0.0757
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0519 0.1023 0.1021
Onchocerca volvulus Netrin receptor homolog 0.0034 0.0038 0.0327
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.041 0.0803 0.3008
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0028 0.0026 0.0234
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0114 0.0202 0.0748
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.0624 0.6087
Plasmodium vivax proline--tRNA ligase, putative 0.004 0.0052 0.0184
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0015 0.0046
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0019 0.0066
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0133 0.024 0.1772
Echinococcus multilocularis glycyl tRNA synthetase 0.004 0.0052 0.0049
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.013 0.0234 0.0231
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0051 0.0073 0.0271
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0076
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0148 0.054
Echinococcus granulosus Niemann Pick C1 protein 0.0311 0.06 0.2751
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Giardia lamblia Short-chain dehydrogenase, putative 0.002 0.0011 0.0141
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0022 0.0015 0.0046
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0019 0.0016
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0174
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0073 0.0275
Trichomonas vaginalis replication factor C large subunit, putative 0.0021 0.0012 0.0094
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0218 0.0412 0.1884
Loa Loa (eye worm) ctsf protein 0.0017 0.0005 0.0027
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0018
Echinococcus granulosus histone lysine methyltransferase setb 0.0084 0.0139 0.063
Onchocerca volvulus 0.0051 0.0073 0.0674
Entamoeba histolytica hypothetical protein 0.0021 0.0012 0.0094
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0322 0.0624 0.6087
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0012 0.0094
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0015 0.0046
Loa Loa (eye worm) patched family protein 0.0019 0.0008 0.0052
Schistosoma mansoni polycystin 1-related 0.002 0.0011 0.0041
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0088 0.0148 0.0554
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0092 0.0873
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0099 0.0171 0.0637
Leishmania major cathepsin L-like protease 0.0065 0.0103 0.0385
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0023 0.0016 0.0044
Mycobacterium ulcerans dihydroorotate dehydrogenase 2 0.1329 0.2667 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0051 0.0073 0.0275
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0073 0.0326
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0231 0.0438 0.0436
Brugia malayi CXXC zinc finger family protein 0.0085 0.0142 0.0528
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0011 0.0027
Echinococcus granulosus WW domain containing oxidoreductase 0.002 0.0011 0.004
Onchocerca volvulus 0.0024 0.0019 0.0137
Onchocerca volvulus 0.0108 0.0189 0.1811
Onchocerca volvulus 0.002 0.0011 0.0064
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0011 0.0086
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0011 0.0086
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0022 0.0015 0.0012
Schistosoma mansoni topbp1 0.0021 0.0012 0.0045
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Onchocerca volvulus 0.002 0.0011 0.0061
Loa Loa (eye worm) cysteine protease 0.0017 0.0005 0.0027
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0114 0.0202 0.1953
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0023 0.0016 0.0049
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.002 0.0011 0.0042
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0051 0.0073 0.0275
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0073 0.0275
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Echinococcus granulosus neuropeptide s receptor 0.0493 0.097 0.4454
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.002 0.0011 0.0027
Brugia malayi hypothetical protein 0.002 0.0011 0.0038
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0097 0.0166 0.062
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0011 0.0033
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0011 0.0086
Echinococcus multilocularis caspase 3 0.0151 0.0276 0.0274
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0011 0.0086
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0033
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0055 0.0082 0.0775
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0026 0.0234
Onchocerca volvulus 0.002 0.0011 0.0064
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0051 0.0073 0.0275
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.002 0.0011 0.0042
Toxoplasma gondii histone lysine methyltransferase SET1 0.0172 0.032 0.1192
Plasmodium vivax metacaspase 1, putative 0.0055 0.0082 0.0297
Trypanosoma brucei Metacaspase-4 0.0055 0.0082 0.0306
Toxoplasma gondii cathepsin CPL 0.0017 0.0005 0.0008
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0077 0.0075
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0079 0.0131 0.049
Schistosoma mansoni lamin 0.0029 0.0028 0.0105
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0004 0.0015
Schistosoma mansoni patched 1 0.0133 0.024 0.0902
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0011 0.0042
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0041 0.0052 0.0196
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0088 0.0148 0.1424
Leishmania major seryl-tRNA synthetase, putative 0.0016 0.0003 0.0009
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0041 0.0052 0.0196
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0023 0.0016 0.0044
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0024 0.0019 0.0161
Toxoplasma gondii ATPase, AAA family protein 0.0021 0.0012 0.0036
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0022 0.0015 0.0056
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0011 0.0086
Mycobacterium ulcerans acyl-CoA synthetase 0.0299 0.0576 0.2152
Leishmania major cathepsin L-like protease 0.0065 0.0103 0.0385
Loa Loa (eye worm) fibroinase 0.0017 0.0005 0.0027
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0019 0.0016
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0015 0.0046
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0004 0.0001
Brugia malayi Patched related family protein 12 0.0019 0.0008 0.0027
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0023 0.0016 0.0044
Leishmania major short chain dehydrogenase/reductase, putative 0.002 0.0011 0.0042
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Echinococcus granulosus importin subunit beta 1 0.0028 0.0027 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Brugia malayi Death domain containing protein 0.0034 0.0038 0.0139
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0077 0.0289
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0022 0.0015 0.0056
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0023 0.0016 0.0049
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0011 0.0009
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0019 0.007
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0017 0.0066
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0249 0.0474 0.3503
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0075 0.0123 0.0447
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.013 0.0234 0.0231
Loa Loa (eye worm) hypothetical protein 0.0028 0.0027 0.0189
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0097 0.0166 0.1604
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0051 0.0073 0.0326
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Trypanosoma cruzi oxidoreductase-like protein, putative 0.002 0.0011 0.0042
Brugia malayi hypothetical protein 0.0027 0.0025 0.0088
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0033
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0082
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Echinococcus granulosus GPCR family 2 0.013 0.0234 0.1063
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.002 0.0011 0.0033
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0073 0.0271
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.002 0.0011 0.0042
Echinococcus granulosus prolyl tRNA synthetase mitochondrial 0.013 0.0235 0.1068
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.004 0.0052 0.0049
Leishmania major short chain dehydrogenase/reductase, putative 0.002 0.0011 0.0042
Mycobacterium ulcerans glycyl-tRNA synthetase 0.004 0.0052 0.0184
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.004 0.0052 0.0193
Toxoplasma gondii carbonyl reductase 1, putative 0.002 0.0011 0.0033
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0023 0.0016 0.0049
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0011 0.0027
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0011 0.0042
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0114 0.0202 0.1953
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0011 0.0042
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0023 0.0016 0.0049
Brugia malayi Dehydrogenases, short chain protein 2 0.002 0.0011 0.0038
Trichomonas vaginalis antibiotic synthetase, putative 0.0088 0.0148 0.1424
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Schistosoma mansoni steroid dehydrogenase 0.002 0.0011 0.0042
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0082
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.002 0.0011 0.0033
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0028 0.02
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.002 0.0011 0.0009
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0011 0.0086
Echinococcus multilocularis lamin 0.0029 0.0028 0.0026
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0034 0.0038 0.0144
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Mycobacterium ulcerans acyl-CoA synthetase 0.0088 0.0148 0.0545
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0055 0.0082 0.0306
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0028 0.0026 0.0187
Onchocerca volvulus 0.002 0.0011 0.0064
Toxoplasma gondii patched family protein 0.0019 0.0008 0.0021
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0157 0.0289 0.1047
Loa Loa (eye worm) hypothetical protein 0.0681 0.1352 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.0131 0.0959
Trypanosoma cruzi metacaspase, putative 0.0055 0.0082 0.0306
Loa Loa (eye worm) hypothetical protein 0.0133 0.024 0.1772
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0024 0.0019 0.0071
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0012 0.0094
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0061 0.0443
Schistosoma mansoni hypothetical protein 0.0218 0.0412 0.1544
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0051 0.0073 0.0535
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Trypanosoma cruzi metacaspase 5, putative 0.0055 0.0082 0.0306
Schistosoma mansoni cytochrome P450 0.0023 0.0016 0.0058
Schistosoma mansoni aryl hydrocarbon receptor 0.0107 0.0187 0.0702
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0051 0.0073 0.0271
Echinococcus multilocularis caspase 8 0.0055 0.0082 0.0079
Plasmodium falciparum sentrin-specific protease 1 0.0041 0.0052 0.0187
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0051 0.0073 0.0535
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.002 0.0011 0.0027
Echinococcus granulosus cathepsin l1 0.0017 0.0005 0.001
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0022 0.0015 0.0056
Mycobacterium ulcerans acetyl-CoA synthetase 0.0088 0.0148 0.0545
Echinococcus multilocularis survival motor neuron protein 1 0.0485 0.0955 0.0953
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0023 0.0016 0.0044
Echinococcus granulosus histone acetyltransferase KAT2B 0.009 0.0152 0.0689
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0082 0.0775
Giardia lamblia Histone acetyltransferase GCN5 0.008 0.0133 0.2096
Trichomonas vaginalis adenylate cyclase, putative 0.0028 0.0026 0.0234
Schistosoma mansoni rab6-interacting 0.002 0.0011 0.0041
Echinococcus multilocularis sterol regulatory element binding protein 0.0133 0.024 0.0238
Trypanosoma cruzi dihydroorotate dehydrogenase (fumarate), putative 0.1329 0.2667 1
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0011 0.0086
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0073 0.0275
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0519 0.1023 0.1021
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.006 0.0092 0.0335
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0077 0.0732
Leishmania major short chain dehydrogenase, putative 0.002 0.0011 0.0042
Schistosoma mansoni steroid dehydrogenase 0.002 0.0011 0.0042
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0034 0.0038 0.0036
Schistosoma mansoni inositol monophosphatase 0.0114 0.0202 0.0757
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0041 0.0052 0.0488
Brugia malayi Retinol dehydrogenase 12 0.002 0.0011 0.0038
Schistosoma mansoni rab6-interacting 0.002 0.0011 0.0041
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0088 0.0148 0.054
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0011 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0101 0.0738
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.002 0.0011 0.0038
Loa Loa (eye worm) hypothetical protein 0.0051 0.0073 0.0535
Brugia malayi hypothetical protein 0.0019 0.0008 0.0027
Trypanosoma cruzi metacaspase, putative 0.0055 0.0082 0.0306
Wolbachia endosymbiont of Brugia malayi dihydroorotate dehydrogenase 2 0.1329 0.2667 1
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0062
Entamoeba histolytica hypothetical protein 0.0218 0.0412 0.4011
Brugia malayi Pax transcription activation domain interacting protein 0.0021 0.0012 0.0041
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0019 0.0131
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0015 0.0055
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0179 0.0333 0.3222
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0148 0.054
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0079 0.0131 0.1255
Leishmania major glycyl tRNA synthetase, putative 0.0024 0.0019 0.0071
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0025 0.0174
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.002 0.0011 0.0033
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0011 0.0027
Treponema pallidum DNA ligase (lig) 0.0021 0.0012 0.0155
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0322 0.0624 0.6087
Onchocerca volvulus 0.0519 0.1023 1
Schistosoma mansoni hypothetical protein 0.013 0.0234 0.0876
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0028 0.02
Plasmodium vivax steroid dehydrogenase, putative 0.002 0.0011 0.0033
Schistosoma mansoni hypothetical protein 0.0516 0.1018 0.3817
Plasmodium vivax importin-beta 2, putative 0.0028 0.0027 0.009
Brugia malayi Cytochrome P450 family protein 0.0023 0.0016 0.0055
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0016 0.0058
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.0026 0.0234
Mycobacterium tuberculosis Probable prolyl-tRNA synthetase ProS (proline--tRNA ligase) (PRORS) (global RNA synthesis factor) (proline translase) 0.0114 0.0202 0.0743
Brugia malayi Cytochrome P450 family protein 0.0023 0.0016 0.0055
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0131
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Plasmodium vivax histidine--tRNA ligase, putative 0.0024 0.0019 0.0062
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0023 0.0016 0.0049
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0004 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0015 0.0055
Toxoplasma gondii GAF domain-containing protein 0.0057 0.0086 0.0313
Plasmodium falciparum acyl-CoA synthetase 0.0223 0.0423 0.1577
Schistosoma mansoni steroid dehydrogenase 0.002 0.0011 0.0042
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0015 0.0055
Leishmania major 4-coumarate:coa ligase-like protein 0.0299 0.0576 0.2159
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0005 0.0027
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0019 0.0075
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0023 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0174
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0024 0.009
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.002 0.0011 0.0086
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0131
Trypanosoma cruzi short-chain dehydrogenase, putative 0.002 0.0011 0.0042
Toxoplasma gondii cytochrome p450 superfamily protein 0.0023 0.0016 0.0049
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0079 0.0131 0.1255
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0023 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0131
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0028 0.0027 0.0103
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0024 0.0019 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0131 0.1255
Echinococcus granulosus muscleblind protein 0.0165 0.0304 0.1388
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.0092 0.0344
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0155 0.0284 0.1055
Trichomonas vaginalis bromodomain-containing protein, putative 0.009 0.0152 0.1467
Schistosoma mansoni short chain dehydrogenase 0.002 0.0011 0.0042
Schistosoma mansoni hypothetical protein 0.0128 0.0231 0.0865
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0028 0.0026 0.0568
Echinococcus granulosus glycyl tRNA synthetase 0.004 0.0052 0.0226
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0019 0.0131
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0022
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0011 0.0042
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0103 0.0385
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0088 0.0148 0.054
Plasmodium falciparum glycine--tRNA ligase 0.0024 0.0019 0.0062
Echinococcus granulosus intermediate filament protein 0.0029 0.0028 0.0118
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0077 0.0289
Trypanosoma cruzi seryl-tRNA synthetase 0.0016 0.0003 0.0009
Toxoplasma gondii oxidoreductase, putative 0.002 0.0011 0.0033
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0022 0.0015 0.0012
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.013 0.0234 0.0872
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0012 0.0094
Loa Loa (eye worm) hypothetical protein 0.0459 0.0902 0.667
Schistosoma mansoni importin beta-1 0.0028 0.0027 0.01
Brugia malayi cytochrome P450 0.0023 0.0016 0.0055
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0079 0.0131 0.1255
Schistosoma mansoni microsomal glutathione s-transferase 0.0231 0.0438 0.1644
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0023 0.0016 0.0049
Leishmania major importin beta-1 subunit, putative 0.0023 0.0016 0.006
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0063 0.0097 0.0436
Leishmania major hypothetical protein, conserved 0.0022 0.0015 0.0055
Loa Loa (eye worm) hypothetical protein 0.0055 0.0082 0.0596
Brugia malayi nuclear receptor NHR-88 0.0051 0.0073 0.0271
Schistosoma mansoni steroid dehydrogenase 0.002 0.0011 0.0042
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0299 0.0576 0.2126
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0011 0.0033
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0077 0.0344
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.004 0.0052 0.0193
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.009 0.0152 0.0562
Leishmania major dehydrogenase-like protein 0.002 0.0011 0.0042
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0103 0.0385
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0061 0.0269
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0011 0.0027
Brugia malayi Dehydrogenases, short chain protein 30 0.002 0.0011 0.0038
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Loa Loa (eye worm) latrophilin receptor protein 2 0.013 0.0234 0.172
Schistosoma mansoni acetyl-CoA synthetase 0.0088 0.0148 0.0554
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0011 0.0009
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0033
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0274
Plasmodium vivax vivapain-2 0.0017 0.0005 0.0008
Trichomonas vaginalis guanylate cyclase, putative 0.0028 0.0026 0.0234
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0088 0.0148 0.0514
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0012 0.0094
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0067 0.0106 0.0397
Echinococcus granulosus death domain containing protein 0.0034 0.0038 0.0164
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Trypanosoma brucei oxidoreductase-like protein 0.002 0.0011 0.0042
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0022 0.0015 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0062
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0191 0.0358 0.1342
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0011 0.0039
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0033
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0121 0.0215 0.0979
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0019 0.0016
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0011 0.0042
Loa Loa (eye worm) Ulp1 protease 0.0097 0.0166 0.1222
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Echinococcus granulosus oxidoreductase 0.002 0.0011 0.004
Echinococcus granulosus carbonyl reductase 1 0.002 0.0011 0.004
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0023 0.0016 0.0044
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.004 0.0052 0.0226
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0005 0.0018
Loa Loa (eye worm) oxidoreductase 0.002 0.0011 0.0076
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0061 0.0224
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0021 0.0012 0.0003
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0011 0.0141
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.0092 0.0089
Trypanosoma brucei metacaspase MCA3 0.0055 0.0082 0.0306
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0171 0.0316 0.2334
Mycobacterium leprae Conserved hypothetical protein 0.0023 0.0016 0.0016
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Brugia malayi Cytochrome P450 family protein 0.0023 0.0016 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Schistosoma mansoni steroid dehydrogenase 0.002 0.0011 0.0042
Loa Loa (eye worm) doublecortin family protein 0.002 0.0011 0.0073
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Giardia lamblia Prolyl-tRNA synthetase 0.004 0.0052 0.0789
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0011 0.0033
Onchocerca volvulus 0.002 0.0011 0.0064
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0027 0.009
Loa Loa (eye worm) seryl-tRNA synthetase 0.0016 0.0003 0.0011
Entamoeba histolytica acyl-CoA synthetase, putative 0.0299 0.0576 0.5619
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0012 0.0045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0103 0.0385
Brugia malayi follicle stimulating hormone receptor 0.0249 0.0474 0.1776
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0041 0.0052 0.0192
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0023 0.0016 0.0044
Schistosoma mansoni RAR-like nuclear receptor 0.0051 0.0073 0.0275
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0003 0.0001
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.004 0.0052 0.048
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0218 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0082 0.0775
Onchocerca volvulus 0.0088 0.0148 0.1405
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0098 0.0365
Onchocerca volvulus 0.0067 0.0106 0.0993
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0077 0.0563
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.002 0.0011 0.0038
Loa Loa (eye worm) hypothetical protein 0.0159 0.0293 0.2158
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0055 0.0082 0.0302
Loa Loa (eye worm) oxidoreductase 0.002 0.0011 0.0076
Toxoplasma gondii exonuclease III APE 0.006 0.0092 0.0335
Entamoeba histolytica hypothetical protein 0.0023 0.0016 0.0131
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.002 0.0011 0.0042
Plasmodium falciparum phosphodiesterase gamma, putative 0.0022 0.0015 0.0046
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.024 0.2332
Leishmania major threonyl-tRNA synthetase, putative 0.004 0.0052 0.0193
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0015 0.0055
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0022 0.0015 0.0012
Trypanosoma cruzi hypothetical protein 0.0097 0.0166 0.0623
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0011 0.0042
Leishmania major hypothetical protein, conserved 0.002 0.0011 0.0042
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0011 0.0033
Loa Loa (eye worm) hypothetical protein 0.0299 0.0576 0.4253
Echinococcus multilocularis Niemann Pick C1 protein 0.0311 0.06 0.0598
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0009 0.0062
Giardia lamblia Threonyl-tRNA synthetase 0.004 0.0052 0.0789
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0088 0.0148 0.0554
Schistosoma mansoni netrin receptor unc5 0.0034 0.0038 0.0143
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0024 0.0019 0.0072
Leishmania major pantothenate kinase subunit, putative 0.0024 0.0019 0.0072
Schistosoma mansoni transcription factor LCR-F1 0.0218 0.0412 0.1544
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0023 0.0016 0.0049
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.002 0.0011 0.0027
Echinococcus multilocularis microtubule associated protein 2 0.0669 0.1327 0.1325
Brugia malayi Steroid receptor seven-up type 2 0.0051 0.0073 0.0271
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0076
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0019 0.0066
Loa Loa (eye worm) dehydrogenase 0.002 0.0011 0.0076
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0011 0.0033
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0028 0.0025
Plasmodium vivax acyl-CoA synthetase, putative 0.0223 0.0423 0.1577
Treponema pallidum prolyl-tRNA synthetase 0.0155 0.0284 0.4524
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0011 0.0086
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0088 0.0148 0.054
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0015 0.0119
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0025 0.0088
Echinococcus granulosus caspase 0.0206 0.0388 0.1773
Echinococcus granulosus sentrin specific protease 7 0.0182 0.0339 0.155
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0003 0.0013
Loa Loa (eye worm) hypothetical protein 0.0165 0.0304 0.2242
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0379
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0022 0.0015 0.0055
Leishmania major cAMP-specific phosphodiesterase, putative 0.0022 0.0015 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0012 0.0094
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0041 0.0052 0.0187
Echinococcus granulosus histidyl tRNA synthetase 0.0024 0.0019 0.0076
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0131
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0011 0.0086
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0088 0.0148 0.0545
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.0624 0.6087
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0088 0.0148 0.1086
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0519 0.1023 1
Trypanosoma cruzi short chain dehydrogenase, putative 0.002 0.0011 0.0042
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.009 0.0152 0.0562
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Onchocerca volvulus 0.0299 0.0576 0.5608
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0023 0.0016 0.0049
Echinococcus granulosus neuropeptide receptor A26 0.0493 0.097 0.4454
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.004 0.0052 0.0189
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0011 0.0027
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.002 0.0075
Mycobacterium ulcerans putative regulatory protein 0.0057 0.0086 0.0313
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0051 0.0073 0.0071
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0023 0.0016 0.0044
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0023 0.0016 0.0049
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0023 0.0016 0.0044
Onchocerca volvulus 0.0021 0.0012 0.0072
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0016 0.0131
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0101
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0033
Leishmania major dihydroorotate dehydrogenase 0.1329 0.2667 1
Loa Loa (eye worm) oxidoreductase 0.002 0.0011 0.0076
Trypanosoma brucei metacaspase 5, putative 0.0055 0.0082 0.0306
Loa Loa (eye worm) CXXC zinc finger family protein 0.0085 0.0142 0.1042
Schistosoma mansoni steroid dehydrogenase 0.002 0.0011 0.0042
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0041 0.0052 0.0488
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0015 0.0046
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0223 0.0423 1
Trichomonas vaginalis set domain proteins, putative 0.0519 0.1023 0.9999
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0218 0.081
Brugia malayi Cathepsin L-like precursor 0.0017 0.0005 0.0014
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0012 0.0094
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.0026 0.0234
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Brugia malayi tailless protein 0.0024 0.0019 0.0066
Giardia lamblia Hypothetical protein 0.0022 0.0015 0.0196
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0022 0.0015 0.0119
Echinococcus multilocularis FTZ F1 alpha 0.0051 0.0073 0.0071
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.0092 0.1435
Loa Loa (eye worm) hypothetical protein 0.0223 0.0423 0.312
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0062
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.0092 0.0873
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0182 0.0339 0.1272
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0011 0.0086
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0103 0.0385
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0051 0.0073 0.0674
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0051 0.0073 0.0071
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0084 0.0139 0.0137
Entamoeba histolytica cysteine protease, putative 0.0017 0.0005 0.0022
Schistosoma mansoni glycyl-tRNA synthetase 0.004 0.0052 0.0193
Loa Loa (eye worm) hypothetical protein 0.0179 0.0333 0.2456
Brugia malayi nuclear hormone receptor 0.0051 0.0073 0.0271
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0023 0.0016 0.0049
Echinococcus granulosus hypothetical protein 0.002 0.0011 0.004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Toxoplasma gondii patched family protein 0.0019 0.0008 0.0021
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.014
Brugia malayi Bromodomain containing protein 0.0085 0.0142 0.0529
Loa Loa (eye worm) hypothetical protein 0.0029 0.0028 0.02
Schistosoma mansoni hypothetical protein 0.0128 0.0231 0.0865
Trypanosoma cruzi metacaspase, putative 0.0055 0.0082 0.0306
Toxoplasma gondii patched family protein 0.0019 0.0008 0.0021
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0022 0.0015 0.0196
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0019 0.0075
Brugia malayi dehydrogenases, short chain protein 2 0.002 0.0011 0.0038
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0079 0.0131 0.0486
Brugia malayi nuclear receptor NHR-67 0.0024 0.0019 0.0066
Onchocerca volvulus 0.0019 0.0008 0.0033
Mycobacterium ulcerans oxidoreductase 0.002 0.0011 0.0033
Onchocerca volvulus 0.0028 0.0026 0.0212
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0082
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0024 0.0019 0.0132
Loa Loa (eye worm) hypothetical protein 0.0485 0.0955 0.7061
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0082 0.0775
Schistosoma mansoni lozenge 0.0058 0.0087 0.0326
Schistosoma mansoni histidyl-tRNA synthetase 0.0024 0.0019 0.0071
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0079 0.0131 0.1255
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.002 0.0011 0.004
Echinococcus multilocularis replication factor c subunit 1 0.0021 0.0012 0.001
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.0092 0.034
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0041 0.0052 0.0488
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.002 0.0066
Schistosoma mansoni carbonyl reductase 0.002 0.0011 0.0042
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0011 0.004
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0005 0.0002
Brugia malayi hypothetical protein 0.002 0.0011 0.0037
Echinococcus multilocularis inositol monophosphatase 1 0.0114 0.0202 0.0199
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0086 0.0817
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0206 0.0388 0.0385
Loa Loa (eye worm) hypothetical protein 0.0088 0.0148 0.1086
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.002 0.0011 0.0009
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0077 0.0732
Schistosoma mansoni hypothetical protein 0.0023 0.0016 0.0058
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0011 0.0086
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0157 0.0289 0.1071
Mycobacterium ulcerans acyl-CoA synthetase 0.0299 0.0576 0.2152
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0022 0.0015 0.0055
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0223 0.0423 0.1577
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0003 0.0013
Plasmodium vivax hypothetical protein, conserved 0.0057 0.0086 0.0313
Trypanosoma cruzi short chain dehydrogenase, putative 0.002 0.0011 0.0042
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0005 0.0022
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0019 0.0066
Brugia malayi Pre-SET motif family protein 0.0456 0.0896 0.3355
Echinococcus granulosus hypothetical protein 0.002 0.0011 0.004
Brugia malayi DKFZp564C0469 protein 0.0021 0.0012 0.0041
Onchocerca volvulus 0.0085 0.0142 0.1346
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0218 0.0805
Loa Loa (eye worm) hypothetical protein 0.004 0.0052 0.0373
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0103 0.0385
Echinococcus multilocularis Protein lozenge 0.0058 0.0087 0.0084
Echinococcus multilocularis transient receptor potential cation channel 0.002 0.0011 0.0009
Schistosoma mansoni retinal dehydrogenase 0.002 0.0011 0.0042
Onchocerca volvulus Sepiapterin reductase homolog 0.002 0.0011 0.0064
Brugia malayi Niemann-Pick C1 protein precursor 0.0311 0.06 0.2248
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0017 0.0069
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0023 0.0016 0.0044
Trypanosoma cruzi cruzipain precursor, putative 0.0065 0.0103 0.0385
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0088 0.0148 0.0545
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0041 0.0052 0.0196
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Entamoeba histolytica acetyltransferase, GNAT family 0.008 0.0133 0.1276
Trichomonas vaginalis sentrin/sumo-specific protease, senp8, putative 0.0041 0.0052 0.0488
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0011 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0009 0.0062
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0088 0.0148 0.1086
Mycobacterium ulcerans acyl-CoA synthetase 0.0088 0.0148 0.0545
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0519 0.1023 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0011 0.0027
Chlamydia trachomatis DNA ligase 0.0021 0.0012 0.0229
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0148 0.054
Echinococcus granulosus replication factor c subunit 1 0.0021 0.0012 0.0044
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.002 0.0066
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0077 0.0344
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.002 0.0075
Brugia malayi N-terminal motif family protein 0.0179 0.0333 0.1245
Schistosoma mansoni ap endonuclease 0.006 0.0092 0.0344
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0073 0.0271
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0004 0.0015
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0038 0.0139
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0011 0.0042
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0088 0.0148 0.0554
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0021 0.0012 0.0036
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0009 0.0062
Brugia malayi hypothetical protein 0.0024 0.0019 0.0066
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0121 0.0215 0.0213
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0055 0.0082 0.0775
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0088 0.0148 0.0545
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0057 0.0086 0.0308
Brugia malayi AMP-binding enzyme family protein 0.0088 0.0148 0.0551
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Loa Loa (eye worm) hypothetical protein 0.0047 0.0065 0.0472
Echinococcus granulosus cytochrome P450 2K1 0.0023 0.0016 0.006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.0624 0.6087
Loa Loa (eye worm) cytochrome P450 0.0023 0.0016 0.0108
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0041 0.0052 0.0187
Brugia malayi isocitrate dehydrogenase 0.0017 0.0004 0.0011
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.004 0.0052 0.0193
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0019 0.0075
Onchocerca volvulus 0.0019 0.0008 0.0033
Echinococcus granulosus tumor protein p63 0.1086 0.2175 1
Plasmodium vivax vivapain-2 0.0017 0.0005 0.0008
Brugia malayi nuclear receptor NHR-88 0.0024 0.0019 0.0066
Brugia malayi oxidoreductase 0.002 0.0011 0.0038
Loa Loa (eye worm) hypothetical protein 0.0055 0.0082 0.0596
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0019 0.007
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0218 0.0819
Brugia malayi nuclear receptor RXR 0.0024 0.0019 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0051 0.0073 0.0271
Brugia malayi hypothetical protein 0.0359 0.0699 0.2618
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0022 0.0015 0.0055
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0016 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0073 0.0271
Leishmania major cytochrome p450-like protein 0.0023 0.0016 0.0058
Leishmania major hypothetical protein, conserved 0.002 0.0011 0.0042
Loa Loa (eye worm) hypothetical protein 0.0088 0.0148 0.1086
Brugia malayi Cell death protein 3 precursor 0.0055 0.0082 0.0302
Toxoplasma gondii dihydroorotate dehydrogenase reveal, putative 0.1329 0.2667 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0019 0.0137
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0051 0.0073 0.0326
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0103 0.0385
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0028 0.0026 0.0234
Leishmania major short chain dehydrogenase-like protein 0.002 0.0011 0.0042
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.004 0.0052 0.0193
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0015 0.0119
Chlamydia trachomatis deubiquitinase/deneddylase Dub1 0.0041 0.0052 0.1185
Schistosoma mansoni bromodomain containing protein 0.0073 0.0119 0.0446
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0019 0.0066
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0022 0.0015 0.0119
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Plasmodium falciparum histone acetyltransferase GCN5 0.008 0.0133 0.0489
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0101
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0131
Loa Loa (eye worm) pigment dispersing factor receptor c 0.041 0.0803 0.5934
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0088 0.0148 0.0545
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0062
Schistosoma mansoni steroid dehydrogenase 0.002 0.0011 0.0042
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0023 0.0016 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0015 0.0055
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.002 0.0011 0.0027
Schistosoma mansoni hypothetical protein 0.0034 0.0038 0.0143
Echinococcus multilocularis RUN 0.002 0.0011 0.0008
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0019 0.0131
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0011 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0086 0.0817
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Loa Loa (eye worm) steroid hormone receptor 0.0051 0.0073 0.0535
Brugia malayi hypothetical protein 0.0485 0.0955 0.3579
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.002 0.0011 0.0042
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0023 0.0016 0.0044
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0023 0.0016 0.0049
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0011 0.0033
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0015 0.0055
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0012 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0076
Schistosoma mansoni hypothetical protein 0.0298 0.0575 0.2157
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0061 0.0228
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0041 0.0052 0.0196
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0299 0.0576 0.2152
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Schistosoma mansoni loxhd1 0.002 0.0011 0.0041
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.002 0.0011 0.0033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0051 0.0073 0.0535
Echinococcus granulosus geminin 0.0516 0.1018 0.4672
Schistosoma mansoni lipoxygenase 0.0085 0.0141 0.0531
Brugia malayi Calcitonin receptor-like protein seb-1 0.041 0.0803 0.3008
Schistosoma mansoni steroid dehydrogenase 0.002 0.0011 0.0042
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0022 0.0015 0.0101
Echinococcus multilocularis musashi 0.0029 0.0028 0.0026
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0005 0.0002
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.002 0.0011 0.0042
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0011 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0051 0.0073 0.0535
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0088 0.0148 0.0545
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0005 0.001
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0028 0.0026 0.0099
Echinococcus multilocularis tumor protein p63 0.1086 0.2175 0.2173
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0022 0.0015 0.0055
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0027
Mycobacterium ulcerans acyl-CoA synthetase 0.0088 0.0148 0.0545
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0022 0.0015 0.0119
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0103 0.0385
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0009 0.0062
Echinococcus granulosus single minded 2 0.0079 0.0131 0.059
Trypanosoma brucei metacaspase MCA2 0.0055 0.0082 0.0306
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.002 0.0011 0.0033
Echinococcus granulosus caspase 3 0.0151 0.0276 0.1259
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0311 0.06 0.5859
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0019 0.0066
Echinococcus granulosus tar DNA binding protein 0.0063 0.0098 0.0441
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0022
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.002 0.0011 0.004
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0023 0.0016 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0009 0.0062
Echinococcus granulosus Ankyrin 0.0034 0.0038 0.0165
Echinococcus multilocularis nibrin 0.0021 0.0012 0.001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0061 0.0269
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0703 0.1397 0.5237
Brugia malayi dehydrogenases, short chain protein 9 0.002 0.0011 0.0038
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0022 0.0015 0.0055
Loa Loa (eye worm) patched family protein 0.0019 0.0008 0.0052
Mycobacterium ulcerans short-chain type oxidoreductase 0.002 0.0011 0.0033
Loa Loa (eye worm) oxidoreductase 0.002 0.0011 0.0076
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0022 0.0015 0.0046
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0028 0.0026 0.0234
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0079 0.0131 0.049
Echinococcus multilocularis aryl hydrocarbon receptor 0.0028 0.0026 0.0024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0055 0.0082 0.0775
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.004 0.0052 0.0189
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0077 0.0732
Leishmania major hypothetical protein, conserved 0.002 0.0011 0.0042
Onchocerca volvulus 0.0029 0.0028 0.0229
Schistosoma mansoni lamin 0.0029 0.0028 0.0105
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Echinococcus multilocularis netrin receptor unc 5 0.0034 0.0038 0.0036
Brugia malayi hypothetical protein 0.0021 0.0012 0.0041
Echinococcus granulosus lamin dm0 0.0029 0.0028 0.0118
Giardia lamblia Sentrin specific protease, putative 0.0041 0.0052 0.0802
Plasmodium falciparum metacaspase-like protein 0.0055 0.0082 0.0297
Onchocerca volvulus Bile acid receptor homolog 0.0051 0.0073 0.0674
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0005 0.0022
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0005 0.0018
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0011 0.0009
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0299 0.0576 0.4253
Echinococcus granulosus carbonyl reductase 1 0.002 0.0011 0.004
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0077 0.1202
Loa Loa (eye worm) oxidoreductase 0.002 0.0011 0.0076
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Onchocerca volvulus 0.0088 0.0148 0.1405
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0101
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0114 0.0202 0.0757
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0079 0.0131 0.049
Schistosoma mansoni hypothetical protein 0.013 0.0234 0.0876
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0024 0.0019 0.0071
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.002 0.0011 0.0042
Echinococcus granulosus inositol monophosphatase 1 0.0114 0.0202 0.0917
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0022 0.0015 0.0119
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0191 0.0358 0.0355
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0299 0.0576 0.2152
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.004 0.0052 0.0184
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0011 0.0033
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0218 0.0819
Brugia malayi Muscleblind-like protein 0.0165 0.0304 0.1137
Toxoplasma gondii glycyl-tRNA synthetase 0.004 0.0052 0.0184
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0097 0.0166 0.1604
Plasmodium falciparum steroid dehydrogenase, putative 0.002 0.0011 0.0033
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0088 0.0148 0.0551
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0299 0.0576 0.2152
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.002 0.0011 0.0042
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.004 0.0052 0.0049
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0011 0.0027
Brugia malayi Zinc finger, C2H2 type family protein 0.0519 0.1023 0.3834
Brugia malayi TAR-binding protein 0.0063 0.0098 0.0365
Echinococcus multilocularis transfer RNA-Lys 0.0079 0.0131 0.0128
Brugia malayi intermediate filament protein 0.0029 0.0028 0.0101
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Schistosoma mansoni intermediate filament proteins 0.0029 0.0028 0.0105
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.002 0.0011 0.0033
Schistosoma mansoni coup transcription factor 0.0051 0.0073 0.0275
Schistosoma mansoni hypothetical protein 0.0128 0.0231 0.0865
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0011 0.0027
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0041 0.0052 0.0488
Chlamydia trachomatis threonine--tRNA ligase 0.004 0.0052 0.1167
Schistosoma mansoni chromosome transmission fidelity factor 0.0021 0.0012 0.0045
Echinococcus granulosus FTZ F1 alpha 0.0051 0.0073 0.0326
Mycobacterium ulcerans threonyl-tRNA synthetase 0.004 0.0052 0.0184
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0016 0.0131
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.004 0.0052 0.0193
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0023 0.0016 0.0049
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0067 0.0106 0.0103
Onchocerca volvulus Protein patched homolog 0.0019 0.0008 0.0033
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0073 0.0326
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0061 0.0058
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0703 0.1397 0.6419
Leishmania major oxidoreductase-like protein 0.002 0.0011 0.0042
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0092 0.0335
Brugia malayi Uncoordinated protein 44 0.0034 0.0038 0.0139
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.004 0.0052 0.048
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0011 0.0027
Plasmodium falciparum replication factor C subunit 1, putative 0.0021 0.0012 0.0036
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0011 0.0033
Mycobacterium ulcerans dehydrogenase/reductase 0.002 0.0011 0.0033
Trypanosoma brucei metacaspase 0.0055 0.0082 0.0306
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0023 0.0016 0.0044
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0079 0.0131 0.049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0022
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0023 0.0016 0.0049
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0092 0.0335
Loa Loa (eye worm) hypothetical protein 0.0037 0.0045 0.0328
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0131
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0088 0.0148 0.0551
Trypanosoma brucei dihydroorotate dehydrogenase (fumarate) 0.1329 0.2667 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0051 0.0073 0.0271
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0079 0.0131 0.1255
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.03 0.0578 0.2169
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0025 0.0092
Schistosoma mansoni caspase-7 (C14 family) 0.0055 0.0082 0.0306
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Brugia malayi hypothetical protein 0.002 0.0011 0.0037
Leishmania major hypothetical protein, conserved 0.002 0.0011 0.0042
Plasmodium falciparum importin beta, putative 0.0028 0.0027 0.009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0019 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0026 0.0234
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.0624 0.6087
Loa Loa (eye worm) inositol-1 0.0114 0.0202 0.1486
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.0624 0.6087
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0019 0.007
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.002 0.0011 0.0027
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0298 0.0575 0.4249
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0073 0.0271
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0022 0.0015 0.0012
Leishmania major protein kinase, putative 0.0032 0.0035 0.0132
Plasmodium vivax replication factor C subunit 1, putative 0.0021 0.0012 0.0036
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.002 0.0011 0.0064
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.007 0.0112 0.0504
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0022 0.0015 0.0051
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.03 0.0578 0.0576
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0174
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.002 0.0011 0.0042
Schistosoma mansoni cpg binding protein 0.0085 0.0142 0.0532
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0022 0.0015 0.0119
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.002 0.0011 0.0064
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Onchocerca volvulus 0.002 0.0011 0.0064
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0076
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Trypanosoma brucei SUMO1/Ulp2, putative 0.0041 0.0052 0.0196
Schistosoma mansoni histidyl-tRNA synthetase 0.0024 0.0019 0.0071
Plasmodium vivax phosphodiesterase gamma, putative 0.0022 0.0015 0.0046
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0004 0.0006
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0012 0.0045
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0004 0.0001
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Loa Loa (eye worm) acetyltransferase 0.03 0.0578 0.4273
Schistosoma mansoni cpg binding protein 0.0091 0.0155 0.0583
Schistosoma mansoni ap endonuclease 0.006 0.0092 0.0344
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.0092 0.0335
Plasmodium vivax glycine--tRNA ligase, putative 0.004 0.0052 0.0184
Plasmodium vivax proline--tRNA ligase, putative 0.013 0.0235 0.0871
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Loa Loa (eye worm) Sars1 protein 0.0016 0.0003 0.0011
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0155 0.0284 0.1055
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.002 0.0011 0.0027
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0011 0.0042
Brugia malayi Patched protein homolog 1 0.0019 0.0008 0.0027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.0624 0.6087
Onchocerca volvulus 0.0019 0.0008 0.0033
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0055 0.0082 0.0297
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.002 0.0066
Leishmania major cytochrome p450-like protein 0.0023 0.0016 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0005 0.0022
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0022 0.0015 0.0051
Leishmania major cathepsin L-like protease 0.0017 0.0005 0.0018
Echinococcus granulosus Niemann Pick C1 protein 0.0444 0.0871 0.3997
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.002 0.0075
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0023 0.0016 0.0044
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0024 0.0019 0.0161
Brugia malayi Patched family protein 0.0019 0.0008 0.0027
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0005 0.0008
Leishmania major 4-coumarate:coa ligase-like protein 0.0299 0.0576 0.2159
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0011 0.0027
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0004 0.0015
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0021 0.0012 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0076
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0098 0.0096
Echinococcus granulosus RUN 0.002 0.0011 0.0039
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0011 0.0086
Schistosoma mansoni carbonyl reductase 0.002 0.0011 0.0042
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0079 0.0131 0.1255
Loa Loa (eye worm) hypothetical protein 0.0311 0.06 0.4435
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0019 0.007
Loa Loa (eye worm) hypothetical protein 0.0069 0.0109 0.0799
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0011 0.0033
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0019 0.0016
Mycobacterium leprae Possible regulatory protein 0.0028 0.0026 0.0057
Brugia malayi CHE-14 protein 0.0133 0.024 0.0898
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0022 0.0015 0.0119
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.1329 0.2667 1
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0079 0.0131 0.0128
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0011 0.0086
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0016 0.0131
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0005 0.001
Onchocerca volvulus 0.0019 0.0008 0.0033
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0021 0.0012 0.0041
Schistosoma mansoni ankyrin 23/unc44 0.0034 0.0038 0.0143
Trichomonas vaginalis steroid dehydrogenase, putative 0.002 0.0011 0.0086
Brugia malayi hypothetical protein 0.0218 0.0412 0.1541
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0012 0.0045
Schistosoma mansoni caspase-3 (C14 family) 0.0206 0.0388 0.1454
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0011 0.0033
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0011 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0051 0.0073 0.0535
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0019 0.0016
Entamoeba histolytica hypothetical protein 0.0218 0.0412 0.4011
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0022 0.0015 0.0012
Onchocerca volvulus 0.002 0.0011 0.0064
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.0624 0.6087
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0088 0.0148 0.0545
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0329 0.0637 0.0634
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0011 0.0039
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.002 0.0011 0.0086
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.002 0.0011 0.0027
Schistosoma mansoni microtubule-associated protein tau 0.0669 0.1327 0.4976
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0028 0.0101
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0015 0.0055
Trypanosoma cruzi histidyl-tRNA synthetase 0.0024 0.0019 0.0071
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0051 0.0073 0.0071
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0131
Brugia malayi Met-10+ like-protein 0.0114 0.0202 0.0754
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0276
Schistosoma mansoni hypothetical protein 0.0516 0.1018 0.3817
Echinococcus granulosus expressed conserved protein 0.0141 0.0257 0.1171
Echinococcus multilocularis protein patched 0.0133 0.024 0.0238
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0052
Trypanosoma brucei protein kinase, putative 0.0053 0.0077 0.0289
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0019 0.007

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 20 mg kg-1 Analgesic activity against acetic acid induced writhing test in mouse after peroral administration ChEMBL. 3133478
ED50 (functional) = 20 mg kg-1 Anti-inflammatory activity against carrageenan-induced foot edema in rat after peroral administration ChEMBL. 3133478
ED50 (functional) = 20 mg kg-1 Analgesic activity against acetic acid induced writhing test in mouse after peroral administration ChEMBL. 3133478

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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