Detailed information for compound 46684

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 546.598 | Formula: C27H26N6O5S
  • H donors: 3 H acceptors: 6 LogP: 2.83 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: Nc1ccc(c(n1)C)CNC(=O)C1C=CCn2n1c(=O)n(c2=O)C(C(=O)O)CSc1cccc2c1cccc2
  • InChi: 1S/C27H26N6O5S/c1-16-18(11-12-23(28)30-16)14-29-24(34)20-9-5-13-31-26(37)32(27(38)33(20)31)21(25(35)36)15-39-22-10-4-7-17-6-2-3-8-19(17)22/h2-12,20-21H,13-15H2,1H3,(H2,28,30)(H,29,34)(H,35,36)
  • InChiKey: PAQKSTFKUCDDLU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0272 0.2823 0.4456
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0382 0.4005 0.8673
Schistosoma mansoni DNA topoisomerase II 0.0427 0.4487 0.4487
Trypanosoma brucei DNA topoisomerase III, putative 0.0023 0.0133 0.0203
Echinococcus multilocularis multidrug resistance protein 1 0.0011 0.0005 0.0001
Leishmania major cytochrome p450-like protein 0.0015 0.0046 0.0066
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0022 0.0124 0.0253
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.007 0.064 0.1379
Plasmodium falciparum ferrodoxin reductase-like protein 0.0072 0.0665 0.1044
Echinococcus multilocularis g protein coupled receptor 0.005 0.0422 0.0458
Brugia malayi hypothetical protein 0.0017 0.007 0.0103
Onchocerca volvulus 0.0024 0.0146 0.0472
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.006 0.0095
Echinococcus granulosus serotonin transporter 0.0096 0.092 0.1181
Leishmania major hypothetical protein, conserved 0.0014 0.0032 0.0044
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0221 0.2268 0.3579
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0129 0.1279 0.1395
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0072 0.0665 0.2322
Echinococcus granulosus histone acetyltransferase KAT2B 0.0149 0.1493 0.1919
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0038
Schistosoma mansoni hypothetical protein 0.0038 0.0295 0.0295
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0012 0.0012 0.0016
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0125 0.1231 0.1343
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0231 0.0231
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0065 0.0584 0.0584
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0048 0.0048
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0099 0.015
Plasmodium falciparum glutathione reductase 0.0598 0.6329 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0099 0.015
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Treponema pallidum oxidoreductase 0.0072 0.0665 0.1811
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0012 0.0012 0.0016
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0064 0.0094
Echinococcus granulosus dna polymerase kappa 0.0064 0.0574 0.0735
Trichomonas vaginalis glutamate synthase, putative 0.0072 0.0665 0.1396
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0231 0.0293
Toxoplasma gondii hypothetical protein 0.0014 0.0032 0.0051
Loa Loa (eye worm) glutathione reductase 0.0598 0.6329 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0272 0.2823 0.6116
Echinococcus granulosus voltage gated hydrogen channel 1 0.0014 0.0032 0.0037
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0034 0.0047
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0371 0.0775
Entamoeba histolytica P-glycoprotein-2 0.0011 0.0005 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0161 0.0331
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.005 0.0422 0.0422
Trypanosoma cruzi metacaspase, putative 0.0047 0.039 0.0609
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0307 0.0639
Mycobacterium ulcerans hypothetical protein 0.0021 0.0115 0.024
Brugia malayi Cytochrome P450 family protein 0.0024 0.0146 0.0223
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0015 0.0046 0.0091
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0016 0.006 0.0073
Echinococcus multilocularis glutamate synthase 0.0072 0.0665 0.0723
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0072 0.0665 0.1433
Schistosoma mansoni cpg binding protein 0.0032 0.0231 0.0231
Onchocerca volvulus 0.0024 0.0146 0.0472
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0048 0.0068
Brugia malayi tailless protein 0.0015 0.0048 0.0068
Mycobacterium tuberculosis Conserved hypothetical protein 0.0168 0.1701 0.2681
Onchocerca volvulus 0.0052 0.0449 0.1486
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0155 0.0276
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0034 0.0047
Schistosoma mansoni caspase-7 (C14 family) 0.009 0.086 0.086
Loa Loa (eye worm) carboxylesterase 0.0024 0.0146 0.0225
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0127 0.0159
Entamoeba histolytica recQ family helicase, putative 0.0021 0.0111 0.0235
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0064 0.0077
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0072 0.0665 0.105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0218 0.045
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.005 0.0422 0.0539
Echinococcus multilocularis abhydrolase domain containing 3 0.0038 0.0291 0.0314
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0101
Trypanosoma brucei Heat shock protein 83, putative 0.0022 0.0124 0.019
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0014 0.0032 0.0037
Giardia lamblia 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0106 0.1025 0.2406
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0306 0.0484
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.039 0.0814
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0029 0.0039
Toxoplasma gondii hypothetical protein 0.0014 0.0032 0.0051
Echinococcus multilocularis lamin 0.0029 0.0193 0.0207
Brugia malayi hypothetical protein 0.005 0.0422 0.0659
Treponema pallidum sodium- and chloride- dependent transporter 0.0096 0.092 0.2628
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0231 0.0293
Brugia malayi Cell death protein 3 precursor 0.009 0.086 0.1352
Echinococcus multilocularis potassium large conductance calcium activated 0.0014 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0038 0.0291 0.0454
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0422 0.0422
Toxoplasma gondii hypothetical protein 0.0038 0.0291 0.0459
Echinococcus multilocularis two pore calcium channel protein 2 0.0014 0.0032 0.0031
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0155 0.0239
Echinococcus granulosus peptide allatostatin:somatostatin 0.005 0.0422 0.0539
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0306 0.0655
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0584 0.0747
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.005 0.0426 0.0462
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0231 0.0231
Brugia malayi Tachykinin-like peptides receptor 99D 0.005 0.0422 0.0659
Loa Loa (eye worm) voltage-gated calcium channel 0.0014 0.0032 0.0045
Brugia malayi nuclear hormone receptor 0.0032 0.0231 0.0357
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0014 0.0032 0.0092
Mycobacterium ulcerans two component regulator - sensor kinase 0.0022 0.0124 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0266 0.0553
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.0046 0.0066
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0024 0.0146 0.0223
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0155 0.0328
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0231 0.0359
Trypanosoma cruzi adrenodoxin precursor, putative 0.0012 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0162 0.0332
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.006 0.0088
Leishmania major 2,3-bisphosphoglycerate-independent phosphoglycerate mutase-like 0.0017 0.0071 0.0106
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.011 0.0173
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0046 0.0073
Treponema pallidum hypothetical protein 0.0049 0.0414 0.1009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0293 0.0609
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0172 0.0266
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0049 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0574 0.09
Echinococcus granulosus acetylcholinesterase 0.0144 0.1432 0.1841
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0012 0.0012 0.0011
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0014 0.0032 0.0031
Mycobacterium ulcerans DNA polymerase IV 0.0064 0.0574 0.1236
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0291 0.0605
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.039 0.0814
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0049 0.0071
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0014 0.0032 0.0032
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0466 0.073
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0057 0.0083
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0048 0.007
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.005 0.0422 0.0458
Schistosoma mansoni disulfide oxidoreductase 0.0072 0.0665 0.0665
Trypanosoma brucei metacaspase MCA2 0.0047 0.039 0.0609
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0249 0.2568 0.9094
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0048 0.0048
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0017 0.0071 0.0106
Schistosoma mansoni opsin-like receptor 0.005 0.0422 0.0422
Loa Loa (eye worm) hypothetical protein 0.0081 0.076 0.1195
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0072 0.0665 0.105
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0038 0.0291 0.0605
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0231 0.0231
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0182 0.1846 0.2911
Schistosoma mansoni cpg binding protein 0.0032 0.0231 0.0231
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0449 0.0449
Plasmodium vivax PST-A protein 0.0038 0.0291 0.0459
Trichomonas vaginalis sensor histidine kinase, putative 0.0022 0.0124 0.0253
Brugia malayi Dopamine receptor 0.005 0.0422 0.0659
Echinococcus multilocularis G protein coupled receptor 139 0.005 0.0422 0.0458
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0266 0.0421
Schistosoma mansoni terminal deoxycytidyl transferase 0.0036 0.027 0.027
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0182 0.1846 0.2911
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0584 0.0635
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0427 0.4487 0.7086
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0015 0.0046 0.0091
Onchocerca volvulus 0.0072 0.0665 0.2206
Trypanosoma cruzi serine peptidase, putative 0.0038 0.0291 0.0453
Onchocerca volvulus 0.0015 0.0048 0.0144
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0016 0.006 0.006
Onchocerca volvulus 0.0044 0.0355 0.1171
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0099 0.015
Echinococcus multilocularis voltage dependent calcium channel 0.0129 0.1279 0.1395
Brugia malayi steroid hormone receptor 0.0032 0.0231 0.0357
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0072 0.0665 0.1044
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0369 0.0577
Onchocerca volvulus 0.0016 0.006 0.0185
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Toxoplasma gondii heat shock protein HSP90 0.0022 0.0124 0.0197
Loa Loa (eye worm) CYP4Cod1 0.0024 0.0146 0.0225
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0047 0.039 0.0608
Plasmodium vivax SET domain protein, putative 0.0032 0.0233 0.0368
Plasmodium vivax thioredoxin reductase, putative 0.0598 0.6329 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0048 0.0048
Plasmodium falciparum multidrug resistance protein 1 0.0011 0.0005 0.0001
Echinococcus granulosus short transient receptor potential channel 6 0.0014 0.0034 0.0039
Brugia malayi Cyclic-nucleotide gated cation channel 0.0019 0.0088 0.0131
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0296 0.046
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0029 0.004
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0005 0.0002
Schistosoma mansoni endoplasmin 0.0022 0.0124 0.0124
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0288 0.2995 1
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0422 0.0539
Plasmodium vivax lysophospholipase, putative 0.0449 0.4729 0.7472
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0155 0.0328
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0272 0.2823 0.4456
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0438 0.4613 0.9755
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0015 0.0046 0.0091
Schistosoma mansoni hypothetical protein 0.0179 0.1819 0.1819
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.009
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0308 0.048
Schistosoma mansoni hypothetical protein 0.005 0.0422 0.0422
Brugia malayi G-protein coupled receptor 0.005 0.0422 0.0659
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0129 0.1279 0.1395
Treponema pallidum thioredoxin reductase (trxB) 0.0072 0.0665 0.1811
Loa Loa (eye worm) hypothetical protein 0.0144 0.1432 0.2259
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0036 0.027 0.0421
Entamoeba histolytica P-glycoprotein-5 0.0011 0.0005 0.0011
Toxoplasma gondii exonuclease III APE 0.002 0.0099 0.0157
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0272 0.2823 0.4456
Onchocerca volvulus 0.0024 0.0146 0.0472
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0014 0.0032 0.0043
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0065 0.0096
Brugia malayi hypothetical protein 0.0015 0.0048 0.0068
Schistosoma mansoni alpha-1 adrenergic receptor 0.005 0.0422 0.0422
Onchocerca volvulus 0.0252 0.2597 0.8671
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0099 0.015
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0151 0.1516 0.2391
Giardia lamblia Pms1-like protein 0.0022 0.0124 0.0283
Trichomonas vaginalis Ferredoxin 1 0.0012 0.0012 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0291 0.0605
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0076 0.0706 0.1109
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.0422 0.0458
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3221 0.6808
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0015 0.0046 0.0065
Entamoeba histolytica P-glycoprotein-1 0.0011 0.0005 0.0011
Echinococcus granulosus neuropeptide receptor 0.005 0.0422 0.0539
Trichomonas vaginalis receptor histidine kinase, putative 0.0022 0.0124 0.0253
Plasmodium vivax PST-A protein 0.0038 0.0291 0.0459
Echinococcus granulosus g protein coupled receptor 0.005 0.0422 0.0539
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0371 0.0775
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0022 0.0124 0.0253
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.006 0.0088
Leishmania major hypothetical protein, conserved 0.0027 0.0172 0.0266
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.032 0.3332 0.5262
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0584 0.0915
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0233 0.0295
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0092 0.0874 0.1375
Trypanosoma brucei heat shock protein 90, putative 0.0022 0.0124 0.019
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0023 0.0133 0.0133
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.005 0.0422 0.0458
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0032 0.0031
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0029 0.0051
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0398 0.0621
Schistosoma mansoni hypothetical protein 0.0179 0.1819 0.1819
Echinococcus multilocularis dro:myosuppressin receptor 0.005 0.0422 0.0458
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0295 0.0295
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Echinococcus granulosus fmrfamide receptor 0.005 0.0422 0.0539
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.005 0.0422 0.0661
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0015 0.0046 0.0091
Toxoplasma gondii transporter, cation channel family protein 0.0076 0.0706 0.1115
Loa Loa (eye worm) inositol-1 0.0039 0.0306 0.0478
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.007
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0233 0.0233
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0574 0.09
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0016 0.006 0.0073
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0048 0.0144
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0398 0.0622
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Trypanosoma brucei protein kinase, putative 0.0054 0.0466 0.073
Schistosoma mansoni cytochrome P450 0.0015 0.0046 0.0046
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0124 0.122 0.2638
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0057 0.0083
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0014 0.0032 0.0043
Trypanosoma brucei Metacaspase-4 0.0047 0.039 0.0609
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0249 0.2568 0.4058
Onchocerca volvulus 0.0029 0.0193 0.0627
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0024 0.0146 0.0184
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0131
Plasmodium falciparum exported lipase 1 0.0038 0.0291 0.0453
Entamoeba histolytica DNA topoisomerase II, putative 0.0427 0.4487 0.9487
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0015 0.0046 0.0065
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0182 0.0288
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0038 0.0291 0.0605
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0038 0.0291 0.0453
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0231 0.0357
Loa Loa (eye worm) hypoxia-induced factor 1 0.0159 0.1604 0.2529
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0272 0.2823 0.4456
Schistosoma mansoni biogenic amine (5HT) receptor 0.005 0.0422 0.0422
Entamoeba histolytica DNA topoisomerase III, putative 0.0023 0.0133 0.0281
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0072 0.0665 0.1044
Brugia malayi olfactory channel protein osm-9 0.0014 0.0034 0.0046
Plasmodium vivax lysophospholipase, putative 0.0038 0.0291 0.0459
Brugia malayi hypothetical protein 0.0016 0.006 0.0088
Loa Loa (eye worm) hypothetical protein 0.0024 0.0146 0.0225
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0398 0.0508
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0665 0.1044
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.039 0.0814
Brugia malayi Flap endonuclease-1 0.0028 0.0182 0.028
Brugia malayi hypothetical protein 0.0038 0.0295 0.0459
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0072 0.0665 0.2322
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0011 0.0005 0.0002
Echinococcus granulosus neuropeptides capa receptor 0.005 0.0422 0.0539
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0231 0.0357
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.0111 0.0117
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0065 0.0095
Brugia malayi hypothetical protein 0.0027 0.0172 0.0265
Echinococcus multilocularis thioredoxin glutathione reductase 0.0598 0.6329 0.6922
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0155 0.0238
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0307 0.0332
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0064 0.0094
Plasmodium falciparum exported lipase 2 0.0038 0.0291 0.0453
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0088 0.0092
Loa Loa (eye worm) solute carrier family 6 member 4 0.0096 0.092 0.1448
Loa Loa (eye worm) hypothetical protein 0.0024 0.0146 0.0225
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0022 0.0124 0.019
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0015 0.0046 0.0065
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0022 0.0124 0.0189
Loa Loa (eye worm) hypothetical protein 0.009 0.086 0.1354
Brugia malayi GRF zinc finger family protein 0.0023 0.0133 0.0202
Loa Loa (eye worm) hypothetical protein 0.0032 0.0231 0.0359
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.005 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0057 0.0109
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0559 0.0883
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0101
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0231 0.0231
Schistosoma mansoni neuropeptide receptor 0.005 0.0422 0.0422
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0231 0.0231
Trypanosoma cruzi NADH dehydrogenase, putative 0.0072 0.0665 0.1044
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0382 0.4005 0.6324
Treponema pallidum fructose-bisphosphate aldolase 0.0309 0.3221 1
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0124 0.122 0.1331
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0072 0.0665 0.1556
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0574 0.09
Onchocerca volvulus 0.0016 0.0052 0.0158
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0331 0.0699
Echinococcus granulosus voltage gated potassium channel 0.0014 0.0032 0.0037
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.011 0.0137
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0422 0.0422
Echinococcus multilocularis conserved hypothetical protein 0.0014 0.0032 0.0031
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0022 0.0124 0.0132
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0306 0.0638
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0022 0.0124 0.0189
Plasmodium vivax hypothetical protein, conserved 0.0047 0.039 0.0616
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0858 0.9142 1
Schistosoma mansoni lamin 0.0029 0.0193 0.0193
Mycobacterium tuberculosis Probable oxidoreductase 0.0012 0.0012 0.0011
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0038 0.0291 0.0605
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0088 0.0109
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.005 0.0422 0.0661
Brugia malayi jmjC domain containing protein 0.0017 0.0064 0.0093
Echinococcus granulosus thioredoxin glutathione reductase 0.0598 0.6329 0.8153
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3221 0.6808
Schistosoma mansoni voltage-gated potassium channel 0.0054 0.0465 0.0465
Brugia malayi nuclear hormone receptor 0.0015 0.0048 0.0068
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0272 0.2823 0.4456
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0072 0.0665 0.1044
Brugia malayi RE15519p 0.005 0.0422 0.0659
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0065 0.0067
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0155 0.0238
Entamoeba histolytica heat shock protein 90, putative 0.0022 0.0124 0.0263
Trypanosoma brucei heat shock protein, putative 0.0022 0.0124 0.019
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0088 0.0109
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.006 0.0088
Echinococcus granulosus neuropeptide receptor A26 0.0537 0.5674 0.7308
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0012 0.0012 0.0012
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0243 0.2505 0.5426
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0422 0.0422
Schistosoma mansoni microtubule-associated protein tau 0.073 0.7763 0.7763
Schistosoma mansoni neuroligin 3 (S09 family) 0.0024 0.0146 0.0146
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0072 0.0665 0.1396
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0081 0.076 0.1193
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.007
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0072 0.0665 0.0723
Brugia malayi PAS domain containing protein 0.0051 0.044 0.0688
Onchocerca volvulus 0.005 0.0422 0.1394
Onchocerca volvulus 0.0032 0.0233 0.0761
Plasmodium falciparum DNA gyrase subunit B 0.0249 0.2568 0.4054
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0124 0.122 0.1567
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0038 0.0291 0.0459
Brugia malayi Cytochrome P450 family protein 0.0035 0.0264 0.041
Schistosoma mansoni biogenic amine receptor 0.005 0.0422 0.0422
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0231 0.0248
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0129 0.1279 0.2014
Loa Loa (eye worm) hypothetical protein 0.0021 0.0115 0.0176
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0231 0.0293
Trypanosoma cruzi DNA topoisomerase III, putative 0.0023 0.0133 0.0203
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0072 0.0665 0.1405
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0064 0.0095
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0005 0.0002
Brugia malayi jmjC domain containing protein 0.0017 0.0064 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0162 0.0332
Schistosoma mansoni neuropeptide f receptor 76f 0.005 0.0422 0.0422
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.007
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0072 0.0665 0.1043
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0065 0.0103
Mycobacterium tuberculosis Conserved hypothetical protein 0.0036 0.027 0.0419
Leishmania major hypothetical protein, conserved 0.0038 0.0291 0.0453
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0099 0.0311
Loa Loa (eye worm) hypothetical protein 0.0045 0.037 0.0579
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0466 0.073
Trichomonas vaginalis heat shock protein, putative 0.0022 0.0124 0.0253
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0129 0.1279 0.1395
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0014 0.0032 0.0031
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0272 0.2823 1
Loa Loa (eye worm) hypothetical protein 0.0183 0.1858 0.2931
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0272 0.2823 0.4456
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0307 0.0478
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0272 0.2823 0.4456
Plasmodium falciparum DNA gyrase subunit A 0.0092 0.0874 0.1376
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0272 0.2823 0.2823
Loa Loa (eye worm) ryanodine receptor 0.0014 0.0032 0.0045
Echinococcus multilocularis muscleblind protein 0.0158 0.159 0.1736
Brugia malayi CXXC zinc finger family protein 0.003 0.0213 0.0328
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0014 0.0032 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0398 0.0831
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0266 0.0553
Brugia malayi AKH receptor 0.005 0.0422 0.0659
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0057 0.0082
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0032 0.0032
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0307 0.0307
Echinococcus multilocularis monoacylglycerol lipase abhd12 0.0038 0.0291 0.0314
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0233 0.0233
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0099 0.0123
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0438 0.4613 0.9754
Loa Loa (eye worm) acetyltransferase 0.0153 0.1539 0.2428
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0034 0.0047
Loa Loa (eye worm) hypothetical protein 0.0032 0.0231 0.0359
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Mycobacterium ulcerans putative regultory protein 0.0022 0.0124 0.0261
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0048 0.0057
Trypanosoma brucei heat shock protein, putative 0.0022 0.0124 0.019
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0398 0.0622
Schistosoma mansoni glutamate synthase 0.0072 0.0665 0.0665
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0146 0.0225
Brugia malayi MGC79044 protein 0.0038 0.0291 0.0452
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0019 0.0088 0.0109
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0012 0.0012 0.0011
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0309 0.3221 0.6811
Plasmodium vivax PST-A protein 0.0438 0.4613 0.7289
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0111 0.0169
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0262 0.0509
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0131
Schistosoma mansoni BC026374 protein (S09 family) 0.0024 0.0146 0.0146
Echinococcus multilocularis somatostatin receptor 0.005 0.0422 0.0458
Plasmodium vivax unspecified product 0.0449 0.4729 0.7472
Echinococcus granulosus glutamate synthase 0.0072 0.0665 0.0852
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0111 0.0224
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Leishmania major 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0106 0.1025 0.1614
Schistosoma mansoni polycystin 1-related 0.0021 0.011 0.011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0076 0.0112
Entamoeba histolytica deoxycytidyl transferase, putative 0.0036 0.027 0.0571
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0011 0.0005 0.0001
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0438 0.4613 0.9754
Onchocerca volvulus 0.0023 0.0133 0.0428
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0029 0.0039
Trichomonas vaginalis Ferredoxin 6 0.0012 0.0012 0.0014
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0593 0.0593
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0111 0.0167
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0005 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0032 0.0032
Toxoplasma gondii hypothetical protein 0.0038 0.0291 0.0459
Onchocerca volvulus 0.005 0.0422 0.1394
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0291 0.0605
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0072 0.0665 0.1044
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0291 0.0605
Schistosoma mansoni hypothetical protein 0.005 0.0422 0.0422
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0111 0.0175
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0072 0.0665 0.1386
Mycobacterium tuberculosis Possible oxygenase 0.0012 0.0012 0.0011
Schistosoma mansoni neuropeptide F-like receptor 0.005 0.0422 0.0422
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0466 0.0737
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0099 0.015
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0422 0.0458
Onchocerca volvulus 0.005 0.0422 0.1394
Mycobacterium tuberculosis Carboxylesterase LipT 0.0024 0.0146 0.0223
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0466 0.073
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0032 0.0031
Onchocerca volvulus 0.003 0.0213 0.0694
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0029 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0231 0.0357
Echinococcus multilocularis multidrug resistance protein 1 0.0011 0.0005 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0272 0.2823 0.4456
Echinococcus multilocularis dna polymerase eta 0.0036 0.027 0.0292
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0014 0.0032 0.0044
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0099 0.0224
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0306 0.0638
Onchocerca volvulus 0.0013 0.0029 0.008
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Mycobacterium ulcerans monoxygenase 0.0072 0.0665 0.1433
Echinococcus granulosus neuropeptide FF receptor 2 0.005 0.0422 0.0539
Echinococcus granulosus TRP transient receptor potential channel 0.0014 0.0032 0.0037
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0032 0.0051
Plasmodium vivax DNA topoisomerase 3, putative 0.0023 0.0133 0.021
Echinococcus granulosus orexin receptor type 2 0.005 0.0422 0.0539
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0479 0.505 0.7977
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0076 0.0706 0.1109
Mycobacterium ulcerans carboxylesterase, LipT 0.0024 0.0146 0.0308
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0422 0.0422
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0032 0.0031
Brugia malayi kinase, mitochondrial precursor 0.0022 0.0124 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0162 0.0332
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0264 0.0412
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0398 0.0622
Trypanosoma cruzi heat shock protein 85, putative 0.0022 0.0124 0.019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0064 0.0574 0.09
Schistosoma mansoni rab6-interacting 0.0021 0.011 0.011
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0574 0.09
Trypanosoma brucei Serine peptidase, Clan SC, Family S09X 0.0038 0.0291 0.0453
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0072 0.0665 0.1043
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0065 0.0067
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0231 0.0755
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0307 0.0477
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0023 0.0133 0.0227
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0578 0.0906
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0466 0.0596
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0231 0.0293
Trypanosoma brucei heat shock protein, putative 0.0022 0.0124 0.019
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0034 0.0039
Brugia malayi voltage-dependent calcium channel 0.0014 0.0032 0.0043
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0002
Brugia malayi hypothetical protein 0.005 0.0422 0.0659
Onchocerca volvulus 0.005 0.0422 0.1394
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0032 0.0037
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0048 0.0057
Echinococcus granulosus ferredoxin 0.0012 0.0012 0.001
Leishmania major hypothetical protein, conserved 0.0012 0.0012 0.0012
Schistosoma mansoni caspase-3 (C14 family) 0.0124 0.122 0.122
Loa Loa (eye worm) hypothetical protein 0.0032 0.0231 0.0359
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0578 0.0907
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0064 0.0064
Schistosoma mansoni thyroid hormone receptor 0.0165 0.1668 0.1668
Trypanosoma brucei metacaspase MCA3 0.0047 0.039 0.0609
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0032 0.0031
Plasmodium falciparum DNA topoisomerase 2 0.0427 0.4487 0.7087
Schistosoma mansoni loxhd1 0.0021 0.011 0.011
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0182 0.0281
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0088 0.0109
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0029 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0162 0.0332
Toxoplasma gondii transporter, cation channel family protein 0.0014 0.0032 0.0051
Trypanosoma brucei DNA topoisomerase IA, putative 0.0023 0.0133 0.0203
Echinococcus granulosus serotonin receptor 0.005 0.0422 0.0539
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.02 0.2043 0.3223
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0598 0.6329 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0048 0.0048
Trypanosoma cruzi NADH dehydrogenase, putative 0.0072 0.0665 0.1044
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0665 0.1044
Plasmodium falciparum alpha/beta hydrolase, putative 0.0038 0.0291 0.0453
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0023 0.0133 0.0203
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Trypanosoma cruzi serine peptidase, putative 0.0038 0.0291 0.0453
Mycobacterium ulcerans NADH dehydrogenase 0.0072 0.0665 0.1433
Loa Loa (eye worm) hypothetical protein 0.0044 0.0355 0.0555
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0422 0.0539
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0306 0.1048
Echinococcus multilocularis para nitrobenzyl esterase 0.0024 0.0146 0.0156
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0034 0.0047
Chlamydia trachomatis hydrolase 0.0038 0.0291 0.1014
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0088 0.0092
Onchocerca volvulus 0.0014 0.0032 0.0092
Echinococcus granulosus ryanodine receptor 44f 0.0014 0.0032 0.0037
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0032 0.0031
Schistosoma mansoni sodium/chloride dependent transporter 0.0096 0.092 0.092
Brugia malayi Probable DNA topoisomerase II 0.0427 0.4487 0.7086
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0071
Brugia malayi Doublecortin family protein 0.0021 0.011 0.0166
Loa Loa (eye worm) hypothetical protein 0.0062 0.0558 0.0876
Brugia malayi hypothetical protein 0.0021 0.011 0.0166
Plasmodium falciparum lysophospholipase, putative 0.0449 0.4729 0.747
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0072 0.0665 0.1044
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0422 0.0458
Loa Loa (eye worm) hypothetical protein 0.0022 0.0124 0.0191
Echinococcus multilocularis tumor protein p63 0.0358 0.3742 0.4091
Echinococcus multilocularis short transient receptor potential channel 6 0.0014 0.0034 0.0033
Echinococcus granulosus neuropeptides capa receptor 0.005 0.0422 0.0539
Onchocerca volvulus 0.0021 0.011 0.035
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0072 0.0665 0.1044
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0307 0.0478
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0088 0.0133
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0016 0.006 0.009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0048 0.0048
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.005 0.0422 0.0539
Plasmodium vivax PST-A protein 0.0038 0.0291 0.0459
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0072 0.0665 0.1043
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0016 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0032 0.0233 0.0362
Plasmodium falciparum alpha/beta hydrolase fold domain containing protein, putative 0.0038 0.0291 0.0453
Schistosoma mansoni lamin 0.0029 0.0193 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0231 0.0357
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0072 0.0665 0.1043
Echinococcus granulosus two pore calcium channel protein 1 0.0014 0.0032 0.0037
Echinococcus granulosus transient receptor potential gamma protein 0.0014 0.0032 0.0037
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Plasmodium falciparum DNA topoisomerase 3, putative 0.0023 0.0133 0.0203
Brugia malayi Serotonin receptor 0.005 0.0422 0.0659
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0438 0.4613 0.9755
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0422 0.0539
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0015 0.0046 0.0065
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3221 0.6808
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.0556 0.0604
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0231 0.0293
Loa Loa (eye worm) G-protein coupled receptor 0.005 0.0422 0.0661
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0057 0.0083
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0015 0.0046 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0291 0.0605
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0466 0.0506
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0161 0.0331
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0422 0.0539
Echinococcus granulosus nuclear factor of activated T cells 5 0.0078 0.0725 0.093
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0065 0.0584 0.0915
Leishmania major Bem46-like serine peptidase,Serine peptidase, Clan SC, Family S09X 0.0038 0.0291 0.0453
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0012 0.0012 0.0011
Echinococcus granulosus potassium voltage gated channel subfamily H 0.005 0.0426 0.0544
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0182 0.0385
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0072 0.0665 0.1044
Schistosoma mansoni opsin-like receptor 0.005 0.0422 0.0422
Echinococcus multilocularis cpg binding protein 0.0032 0.0231 0.0249
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0146 0.0146
Trichomonas vaginalis set domain proteins, putative 0.0251 0.2596 0.5484
Plasmodium falciparum lysophospholipase, putative 0.0438 0.4613 0.7287
Loa Loa (eye worm) melatonin receptor type 1A 0.005 0.0422 0.0661
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0016 0.006 0.0062
Onchocerca volvulus 0.0015 0.0048 0.0144
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0038 0.0291 0.0605
Plasmodium falciparum ferredoxin, putative 0.0012 0.0012 0.0012
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0032 0.0032
Entamoeba histolytica 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0106 0.1025 0.2167
Toxoplasma gondii transporter, cation channel family protein 0.0014 0.0032 0.0051
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0032 0.0031
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0072 0.0665 0.1396
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0272 0.2823 0.4456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0293 0.0609
Plasmodium falciparum metacaspase-like protein 0.0047 0.039 0.0609
Trichomonas vaginalis aldehyde oxidase, putative 0.0367 0.3841 0.812
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0231 0.0357
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0011 0.0005 0.0008
Schistosoma mansoni biogenic amine (5HT) receptor 0.0183 0.1858 0.1858
Plasmodium vivax unspecified product 0.0038 0.0291 0.0459
Schistosoma mansoni biogenic amine receptor 0.005 0.0422 0.0422
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0015 0.0046 0.0065
Trichomonas vaginalis spcc417.12 protein, putative 0.0024 0.0146 0.0299
Echinococcus multilocularis Ankyrin 0.0015 0.005 0.0051
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0032 0.0037
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0233 0.025
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0146 0.0225
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3221 0.6808
Echinococcus granulosus microtubule associated protein 2 0.073 0.7763 1
Brugia malayi Protein C20orf22 0.0038 0.0291 0.0452
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0047 0.039 0.039
Echinococcus multilocularis acetylcholinesterase 0.0144 0.1432 0.1563
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0076 0.0112
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0307 0.0391
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0032 0.0051
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0111 0.0169
Brugia malayi hypothetical protein 0.0044 0.0355 0.0553
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0072 0.0665 0.1433
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0072 0.0665 0.0852
Echinococcus multilocularis transient receptor potential gamma protein 0.0014 0.0032 0.0031
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.005 0.0422 0.0539
Echinococcus multilocularis voltage gated potassium channel 0.0014 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0088 0.0133
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0291 0.0459
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.007
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0096 0.092 0.092
Giardia lamblia DNA topoisomerase III 0.0023 0.0133 0.0303
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0032 0.0031
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0068 0.0082
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0131
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0193 0.0296
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0022 0.0124 0.0156
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0072 0.0665 0.1045
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0155 0.0276
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0022 0.0124 0.0261
Mycobacterium leprae putative cytochrome p450 0.0015 0.0046 0.0038
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0182 0.1846 0.2911
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0068 0.0068
Brugia malayi hypothetical protein 0.0021 0.011 0.0166
Giardia lamblia Fructose-bisphosphate aldolase 0.0309 0.3221 0.7582
Echinococcus multilocularis neuropeptide receptor 0.005 0.0422 0.0458
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0064 0.0066
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.005 0.0426 0.0665
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0369 0.0577
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0127 0.0127
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0182 0.0282
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0127 0.0135
Toxoplasma gondii hypothetical protein 0.0108 0.1053 0.1664
Schistosoma mansoni smdr2 0.0011 0.0005 0.0005
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0438 0.4613 0.9754
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0024 0.0146 0.0299
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0065 0.0096
Brugia malayi Thioredoxin reductase 0.0598 0.6329 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0182 0.1846 0.2911
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0398 0.0622
Plasmodium falciparum endoplasmin, putative 0.0022 0.0124 0.019
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0231 0.0231
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3221 0.6808
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0072 0.0665 0.105
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0173 0.175 0.2759
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0371 0.0587
Plasmodium falciparum BEM46-like protein, putative 0.0038 0.0291 0.0453
Brugia malayi hypothetical protein 0.0129 0.1274 0.2007
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0034 0.0033
Toxoplasma gondii hypothetical protein 0.0052 0.0441 0.0696
Echinococcus granulosus tachykinin peptides receptor 99D 0.005 0.0422 0.0539
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0398 0.0622
Brugia malayi hypoxia-induced factor 1 0.0159 0.1604 0.2528
Mycobacterium ulcerans DNA gyrase subunit B 0.0249 0.2568 0.5563
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0072 0.0665 0.1396
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0101
Onchocerca volvulus 0.005 0.0422 0.1394
Brugia malayi Serotonin receptor 0.005 0.0422 0.0659
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0023 0.0133 0.0167
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0133 0.1322 0.1442
Brugia malayi hypothetical protein 0.005 0.0422 0.0659
Echinococcus granulosus neuroligin 0.0024 0.0146 0.0184
Loa Loa (eye worm) serotonin transporter b 0.0096 0.092 0.1448
Echinococcus granulosus dna polymerase eta 0.0036 0.027 0.0343
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0088 0.0088
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0088 0.0088
Trypanosoma brucei DNA polymerase IV, putative 0.0064 0.0574 0.09
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.007
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0124 0.0197
Giardia lamblia Heat shock protein HSP 90-alpha 0.0022 0.0124 0.0283
Toxoplasma gondii NADPH-glutathione reductase 0.0272 0.2823 0.446
Onchocerca volvulus 0.005 0.0422 0.1394
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0127 0.0192
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0182 0.0195
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0015 0.0046 0.0091
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0272 0.2823 0.4456
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0072 0.0665 0.0723
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.044 0.044
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0466 0.073
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.02 0.2043 0.3223
Onchocerca volvulus 0.005 0.0422 0.1394
Toxoplasma gondii phospholipase/carboxylesterase 0.0038 0.0291 0.0459
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0012 0.0012 0.0012
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0057 0.0083
Entamoeba histolytica heat shock protein 90, putative 0.0022 0.0124 0.0263
Brugia malayi Carboxylesterase family protein 0.0024 0.0146 0.0223
Trypanosoma brucei cytochrome P450, putative 0.0024 0.0146 0.0224
Echinococcus granulosus tumor protein p63 0.0358 0.3742 0.4818
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Loa Loa (eye worm) hypothetical protein 0.0013 0.0029 0.004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Loa Loa (eye worm) ion channel NompC 0.0014 0.0032 0.0045
Brugia malayi cation channel family protein 0.0014 0.0032 0.0043
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0029 0.0051
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0231 0.0359
Brugia malayi Dopamine receptor protein 2 0.005 0.0422 0.0659
Loa Loa (eye worm) TYRA-2 protein 0.005 0.0422 0.0661
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0182 0.0375
Brugia malayi hypothetical protein 0.005 0.0422 0.0659
Mycobacterium ulcerans dehydrogenase 0.0072 0.0665 0.1433
Loa Loa (eye worm) hypothetical protein 0.0017 0.0064 0.0095
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0072 0.0665 0.1386
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.039 0.0814
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.005 0.0422 0.0422
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0048 0.0057
Brugia malayi cation channel family protein 0.0014 0.0032 0.0043
Trypanosoma brucei heat shock protein, putative 0.0022 0.0124 0.019
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0099 0.0149
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0151 0.1515 0.3241
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0065 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0291 0.0605
Leishmania major hypothetical protein, conserved 0.0038 0.0291 0.0453
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.005 0.0073
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0051 0.0433 0.0678
Brugia malayi Muscleblind-like protein 0.0158 0.159 0.2506
Echinococcus multilocularis thyroid hormone receptor alpha 0.0165 0.1668 0.1821
Echinococcus multilocularis g protein coupled receptor 0.005 0.0422 0.0458
Echinococcus granulosus sodium and chloride dependent glycine 0.0016 0.006 0.0073
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0014 0.0032 0.0032
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0049 0.0058
Loa Loa (eye worm) doublecortin family protein 0.0021 0.011 0.0168
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0064 0.0064
Plasmodium vivax amine transporter, putative 0.0016 0.006 0.0095
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0057 0.0109
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0088 0.0176
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0272 0.2823 0.446
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0072 0.0665 0.1433
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.005 0.0422 0.0422
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0065 0.0067
Leishmania major DNA polymerase kappa, putative 0.0043 0.0346 0.0539
Echinococcus granulosus heat shock protein 0.0022 0.0124 0.0156
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0182 0.0419
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.006 0.006
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.0038 0.0291 0.0453
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0498 0.0781
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.005 0.0422 0.0458
Plasmodium falciparum transporter, putative 0.0016 0.006 0.0089
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.0422 0.0422
Trypanosoma cruzi monoglyceride lipase, putative 0.0438 0.4613 0.7287
Echinococcus granulosus folate receptor beta 0.0108 0.1053 0.1353
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0111 0.0167
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0155 0.0328
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0466 0.073
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0072 0.0665 0.0852
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0272 0.2823 0.4456
Giardia lamblia [2Fe-2S] ferredoxin 0.0012 0.0012 0.0018
Schistosoma mansoni adrenodoxin 0.0012 0.0012 0.0012
Onchocerca volvulus 0.005 0.0422 0.1394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0293 0.0609
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Echinococcus granulosus biogenic amine 5HT receptor 0.005 0.0422 0.0539
Echinococcus multilocularis voltage dependent calcium channel 0.0129 0.1279 0.1395
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0172 0.0272
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0072 0.0665 0.1044
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0012 0.0012 0.0013
Leishmania major DNA polymerase eta, putative 0.0036 0.027 0.042
Mycobacterium ulcerans oxidoreductase 0.0012 0.0012 0.0016
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0065 0.0079
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0438 0.4613 0.9754
Echinococcus multilocularis fmrfamide receptor 0.005 0.0422 0.0458
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0231 0.0248
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0172 0.0272
Loa Loa (eye worm) DNA topoisomerase III 0.0023 0.0133 0.0204
Echinococcus granulosus para nitrobenzyl esterase 0.0024 0.0146 0.0184
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0072 0.0665 0.1043
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0024 0.0146 0.0225
Echinococcus multilocularis transfer RNA-Gly 0.0014 0.0032 0.0031
Echinococcus granulosus calcium activated potassium channel 0.0014 0.0038 0.0044
Echinococcus multilocularis heat shock protein 0.0022 0.0124 0.0132
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0574 0.09
Brugia malayi hypothetical protein 0.005 0.0422 0.0659
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0023 0.0133 0.0141
Leishmania major monoglyceride lipase, putative 0.0438 0.4613 0.7287
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0015 0.0046 0.0091
Trichomonas vaginalis glutamate synthase, putative 0.0072 0.0665 0.1396
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0191 0.0394
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.006 0.006
Trypanosoma brucei NADH dehydrogenase 0.0072 0.0665 0.1044
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0015 0.0046 0.0091
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0014 0.0032 0.0043
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.007 0.064 0.1379
Trypanosoma brucei heat shock protein 90, putative 0.0022 0.0124 0.019
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0068 0.0099
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0015 0.0046 0.0091
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0014 0.0032 0.0043
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0127 0.0159
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0398 0.0841
Toxoplasma gondii peptidase S15, putative 0.0038 0.0291 0.0459
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.011 0.0137
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0032 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0191 0.0394
Echinococcus multilocularis allatostatin A receptor 0.005 0.0422 0.0458
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0016 0.006 0.006
Echinococcus multilocularis short transient receptor potential channel 6 0.0014 0.0032 0.0031
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0065 0.0097
Echinococcus granulosus BC026374 protein S09 family 0.0024 0.0146 0.0184
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0307 0.0391
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0057 0.0109
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0099 0.0206
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0155 0.0328
Echinococcus granulosus allatostatin A receptor 0.005 0.0422 0.0539
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0188 0.0388
Schistosoma mansoni myosin xvIII 0.005 0.0422 0.0422
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0398 0.0841
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0115 0.024
Brugia malayi nuclear receptor NHR-67 0.0015 0.0048 0.0068
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0038 0.0291 0.0453
Echinococcus multilocularis RUN 0.0021 0.011 0.0116
Brugia malayi neuropeptide F receptor 0.005 0.0422 0.0659
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0005 0.0001
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0072 0.0665 0.1044
Giardia lamblia Glutamate synthase 0.0072 0.0665 0.1556
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0309 0.3221 0.6811
Brugia malayi heat shock protein 90 0.0022 0.0124 0.0189
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0272 0.2823 0.6116
Schistosoma mansoni adenoreceptor 0.005 0.0422 0.0422
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0575 0.0736
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Loa Loa (eye worm) hypothetical protein 0.0024 0.0146 0.0225
Loa Loa (eye worm) carboxylesterase 0.0144 0.1432 0.2259
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0032 0.0031
Echinococcus granulosus phd:f box containing protein 0.0017 0.0064 0.0077
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0022 0.0124 0.0261
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0231 0.0357
Schistosoma mansoni nuclear receptor 0.0015 0.0048 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0438 0.4613 0.9754
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0015 0.0046 0.0091
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0057 0.0083
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0556 0.0604
Schistosoma mansoni neuropeptide receptor 0.005 0.0422 0.0422
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0023 0.0133 0.0167
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0022 0.0124 0.04
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0015 0.0046 0.0091
Echinococcus multilocularis two pore calcium channel protein 1 0.0014 0.0032 0.0031
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0015 0.0046 0.0091
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0367 0.3841 0.812
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0015 0.0046 0.0091
Mycobacterium ulcerans DNA gyrase subunit A 0.0092 0.0874 0.1888
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.005 0.0422 0.0458
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0193 0.0298
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0048 0.0057
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0024 0.0146 0.0308
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0019 0.0088 0.0092
Trypanosoma cruzi DNA polymerase kappa, putative 0.0064 0.0574 0.09
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0032 0.0037
Echinococcus granulosus biogenic amine 5HT receptor 0.0183 0.1858 0.239
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0072 0.0665 0.1396
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0029 0.0051
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0307 0.0332
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0306 0.0477
Giardia lamblia DNA topoisomerase III 0.0023 0.0133 0.0303
Schistosoma mansoni growth hormone secretagogue receptor 0.005 0.0422 0.0422
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0306 0.0648
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0578 0.1244
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0151 0.1516 0.2391
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0032 0.0031
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.005 0.0426 0.0667
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0306 0.0477
Loa Loa (eye worm) voltage-gated potassium channel 0.0014 0.0032 0.0045
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0072 0.0665 0.1386
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0038 0.0291 0.0453
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0422 0.0539
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0153 0.1539 0.1539
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.039 0.0616
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0398 0.0831
Echinococcus multilocularis sodium leak channel non selective protein 0.0014 0.0032 0.0031
Trypanosoma brucei monoglyceride lipase, putative 0.0438 0.4613 0.7287
Plasmodium falciparum alpha/beta-hydrolase, putative 0.0038 0.0291 0.0453
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0065 0.0095
Echinococcus multilocularis ferredoxin adrenodoxin 0.0012 0.0012 0.0009
Trypanosoma cruzi Heat shock protein 83, putative 0.0022 0.0124 0.019
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.007 0.064 0.1004
Brugia malayi acetyltransferase, GNAT family protein 0.0153 0.1539 0.2426
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0033 0.0038
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0048 0.0048
Echinococcus granulosus voltage dependent calcium channel 0.0129 0.1279 0.1643
Brugia malayi hypothetical protein 0.005 0.0422 0.0659
Echinococcus multilocularis geminin 0.0179 0.1819 0.1987
Echinococcus granulosus flap endonuclease 1 0.0028 0.0182 0.023
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0014 0.0032 0.0092
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.007
Entamoeba histolytica disulphide oxidoreductase, putative 0.0072 0.0665 0.1405
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0032 0.0032
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0295 0.0376
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0231 0.0359
Entamoeba histolytica thioredoxin reductase, putative 0.0072 0.0665 0.1405
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0072 0.0665 0.0723
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0015 0.0046 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0291 0.0605
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0072 0.0665 0.105
Mycobacterium ulcerans hypothetical protein 0.0038 0.0291 0.0622
Brugia malayi Melatonin receptor type 1A 0.005 0.0422 0.0659
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Chlamydia trachomatis ferredoxin 0.0012 0.0012 0.0024
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0144 0.1432 0.1432
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0249 0.2568 0.4053
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0016 0.006 0.0062
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0306 0.0477
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0022 0.0124 0.0189
Mycobacterium leprae Probable two-component sensor kinase 0.0022 0.0124 0.0208
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0072 0.0665 0.1044
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0.0004 0.0007
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0231 0.0248
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0272 0.2823 0.4456
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0064 0.0101
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0015 0.0046 0.0065
Mycobacterium ulcerans lysophospholipase 0.0438 0.4613 1
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0064 0.0066
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0231 0.0293
Trypanosoma brucei 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0106 0.1025 0.1614
Loa Loa (eye worm) hypothetical protein 0.0032 0.0231 0.0359
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0288 0.2995 1
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0088 0.0109
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.005 0.0422 0.0458
Trichomonas vaginalis endoplasmin, putative 0.0022 0.0124 0.0253
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0466 0.0466
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0032 0.0037
Mycobacterium tuberculosis Probable two component sensor kinase 0.0022 0.0124 0.0189
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0032 0.0037
Echinococcus multilocularis G-protein coupled receptor, putative 0.005 0.0422 0.0458
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0307 0.0478
Brugia malayi putative neuropeptide receptor 0.005 0.0422 0.0659
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0057 0.0083
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0106 0.1025 0.1614
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0307 0.0391
Trypanosoma cruzi DNA polymerase kappa, putative 0.0064 0.0574 0.09
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0012 0.0012 0.0012
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0064 0.0077
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.009
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0038
Onchocerca volvulus 0.005 0.0422 0.1394
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0032 0.0037
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0371 0.0587
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0111 0.108 0.2294
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0155 0.0328
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0065 0.0096
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0099 0.02
Brugia malayi jmjC domain containing protein 0.0062 0.0556 0.0871
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0307 0.0307
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.0422 0.0539
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0578 0.0913
Loa Loa (eye worm) norepinephrine transporter 0.0096 0.092 0.1448
Loa Loa (eye worm) hypothetical protein 0.0032 0.0231 0.0359
Echinococcus granulosus intermediate filament protein 0.0029 0.0193 0.0243
Trypanosoma cruzi heat shock protein 90, putative 0.0022 0.0124 0.019
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0081 0.076 0.1193
Loa Loa (eye worm) hypothetical protein 0.0096 0.092 0.1448
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0099 0.0149
Leishmania major hypothetical protein, unknown function 0.0014 0.0032 0.0044
Plasmodium vivax ferrodoxin reductase, putative 0.0072 0.0665 0.105
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.007
Schistosoma mansoni calcium-activated potassium channel 0.0014 0.0032 0.0032
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0064 0.0574 0.1204
Echinococcus multilocularis neuropeptide FF receptor 2 0.005 0.0422 0.0458
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0072 0.0665 0.2322
Loa Loa (eye worm) hypothetical protein 0.0027 0.0172 0.0267
Entamoeba histolytica P-glycoprotein-2 0.0011 0.0005 0.0011
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0046 0.0066
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0016 0.006 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0574 0.09
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0015 0.0046 0.0065
Brugia malayi hypothetical protein 0.005 0.0422 0.0659
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0115 0.0187
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0072 0.0665 0.1044
Trypanosoma brucei electron transfer protein, putative 0.0012 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0062 0.0558 0.0876
Loa Loa (eye worm) hypothetical protein 0.0174 0.1757 0.2771
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0022 0.0124 0.019
Trypanosoma brucei mitochondrial DNA polymerase beta 0.032 0.3332 0.5262
Loa Loa (eye worm) hypothetical protein 0.0024 0.0146 0.0225
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0015 0.0046 0.0091
Schistosoma mansoni hypothetical protein 0.0012 0.0014 0.0014
Echinococcus multilocularis neuropeptide Y receptor 0.005 0.0422 0.0458
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0398 0.0622
Brugia malayi Endoplasmin precursor 0.0022 0.0124 0.0189
Mycobacterium ulcerans hydrolase 0.0038 0.0291 0.0622
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0231 0.0357
Echinococcus granulosus heat shock protein 90 0.0022 0.0124 0.0156
Loa Loa (eye worm) hypothetical protein 0.0024 0.0146 0.0225
Mycobacterium ulcerans endonuclease IV 0.0081 0.076 0.1639
Onchocerca volvulus 0.005 0.0422 0.1394
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0155 0.0328
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0022 0.0124 0.0197
Brugia malayi ecdysone receptor 0.0015 0.0048 0.0068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0231 0.0359
Toxoplasma gondii DNA topoisomerase 2, putative 0.0427 0.4487 0.7089
Brugia malayi polk-prov protein 0.0039 0.0308 0.0479
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.005 0.0422 0.0539
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0578 0.1244
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.039 0.0814
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0231 0.0359
Plasmodium vivax alpha/beta hydrolase, putative 0.0038 0.0291 0.0459
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.005 0.0422 0.0659
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0233 0.0368
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3221 0.6808
Schistosoma mansoni voltage-gated potassium channel 0.0054 0.0465 0.0465
Trypanosoma cruzi metacaspase, putative 0.0047 0.039 0.0609
Trypanosoma cruzi DNA topoisomerase II, putative 0.0404 0.4238 0.6694
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.011 0.0116
Echinococcus multilocularis shaker cognate 0.0014 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.007
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0015 0.0046 0.0091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0231 0.0359
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0101
Brugia malayi nuclear receptor RXR 0.0015 0.0048 0.0068
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0072 0.0665 0.1396
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0291 0.0452
Echinococcus granulosus geminin 0.0179 0.1819 0.234
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.007
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0173 0.175 0.3788
Leishmania major p-glycoprotein 0.0011 0.0005 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0032 0.0032
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0064 0.0095
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0032 0.0032
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0015 0.0046 0.0091
Loa Loa (eye worm) hypothetical protein 0.0015 0.005 0.0073
Schistosoma mansoni inositol monophosphatase 0.0039 0.0306 0.0306
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0029 0.0051
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0072 0.0665 0.1396
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0065 0.0096
Brugia malayi glutamate synthase 0.0072 0.0665 0.1043
Trypanosoma cruzi metacaspase 5, putative 0.0047 0.039 0.0609
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.039 0.0616
Brugia malayi Carboxylesterase family protein 0.0024 0.0146 0.0223
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0422 0.0458
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0127 0.0127
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0015 0.0046 0.0091
Brugia malayi nuclear receptor NHR-88 0.0015 0.0048 0.0068
Echinococcus granulosus shaker cognate 0.0014 0.0032 0.0037
Trypanosoma brucei unspecified product 0.0025 0.0151 0.0231
Schistosoma mansoni amine GPCR 0.005 0.0422 0.0422
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0014 0.0032 0.0037
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0233 0.0233
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.011 0.0116
Schistosoma mansoni sodium/chloride dependent transporter 0.0017 0.0066 0.0066
Chlamydia trachomatis DNA gyrase subunit B 0.0249 0.2568 0.9096
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0168
Mycobacterium ulcerans electron transfer protein FdxB 0.0012 0.0012 0.0016
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0584 0.1257
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0295 0.0319
Brugia malayi jmjC domain containing protein 0.0017 0.0064 0.0093
Plasmodium falciparum metacaspase 1 0.0047 0.039 0.0609
Onchocerca volvulus 0.0024 0.0146 0.0472
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0014 0.0011
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0096 0.092 0.1446
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0231 0.0293
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.007
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0032 0.0032
Echinococcus granulosus neuropeptide receptor 0.005 0.0422 0.0539
Plasmodium falciparum flap endonuclease 1 0.0028 0.0182 0.0281
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0087 0.0179
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0021 0.0111 0.0169
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0172 0.0266
Trypanosoma brucei unspecified product 0.0057 0.0498 0.0781
Schistosoma mansoni hypothetical protein 0.0133 0.1322 0.1322
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0023 0.0133 0.0271
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0151 0.1515 0.3277
Brugia malayi sulfakinin receptor protein 0.005 0.0422 0.0659
Brugia malayi hypothetical protein 0.0015 0.0048 0.0068
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0022 0.0124 0.019
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0099 0.021
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0016 0.006 0.0196
Toxoplasma gondii selenide, water dikinase 0.0072 0.0665 0.105
Echinococcus granulosus caspase 8 0.0047 0.039 0.0497
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0048 0.007
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0005 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0231 0.0359
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Echinococcus granulosus voltage dependent calcium channel 0.0076 0.0706 0.0905
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.039 0.0616
Chlamydia trachomatis endonuclease IV 0.0081 0.076 0.2678
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0016 0.006 0.0073
Trypanosoma brucei DNA polymerase eta, putative 0.0036 0.027 0.042
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.009
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.0422 0.0422
Plasmodium falciparum alpha/beta hydrolase, putative 0.0038 0.0291 0.0453
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0064 0.0077
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0466 0.073
Schistosoma mansoni transient receptor potential channel 0.0014 0.0032 0.0032
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0072 0.0665 0.1043
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0032 0.0037
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0213 0.027
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.032 0.3332 0.5262
Brugia malayi nuclear receptor RXR 0.0017 0.0068 0.0099
Echinococcus granulosus short transient receptor potential channel 6 0.0014 0.0032 0.0037
Leishmania major ferredoxin 2fe-2s-like protein 0.0012 0.0012 0.0012
Plasmodium falciparum alpha/beta hydrolase, putative 0.0038 0.0291 0.0453
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.039 0.0814
Plasmodium vivax PST-A protein 0.0038 0.0291 0.0459
Treponema pallidum hypothetical protein 0.006 0.0528 0.1372
Trypanosoma cruzi metacaspase 5, putative 0.0047 0.039 0.0609
Echinococcus multilocularis alpha 1A adrenergic receptor 0.005 0.0422 0.0458
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0005 0.0001
Echinococcus multilocularis serotonin transporter 0.0096 0.092 0.1002
Loa Loa (eye worm) hypothetical protein 0.0289 0.2999 0.4735
Loa Loa (eye worm) hypothetical protein 0.0052 0.0449 0.0704
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0398 0.0623
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0072 0.0665 0.0852
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0127 0.0194
Mycobacterium ulcerans hypothetical protein 0.0038 0.0291 0.0622
Schistosoma mansoni amine GPCR 0.005 0.0422 0.0422
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0032 0.0032
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0014 0.0032 0.0031
Schistosoma mansoni glutamate synthase 0.0072 0.0665 0.0665
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Schistosoma mansoni netrin receptor unc5 0.0015 0.0049 0.0049
Onchocerca volvulus 0.005 0.0422 0.1394
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0278 0.0578
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3221 0.6808
Plasmodium vivax endoplasmin, putative 0.0022 0.0124 0.0197
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0098 0.0148
Onchocerca volvulus 0.0021 0.011 0.035
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0382 0.4005 0.6324
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0088 0.0133
Trypanosoma cruzi DNA topoisomerase III, putative 0.0023 0.0133 0.0203
Echinococcus granulosus sodium leak channel non selective protein 0.0014 0.0032 0.0037
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.005 0.0422 0.0659
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0272 0.2823 0.6116
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0012 0.0012 0.0023
Echinococcus multilocularis heat shock protein 90 0.0022 0.0124 0.0132
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0466 0.1089
Loa Loa (eye worm) calcium channel 0.0129 0.1279 0.2016
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0422 0.0539
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0146 0.0146
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0022 0.0124 0.0253
Echinococcus granulosus potassium large conductance calcium activated 0.0014 0.0032 0.0037
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0111 0.0224
Echinococcus granulosus neuropeptide Y receptor 0.005 0.0422 0.0539
Schistosoma mansoni heat shock protein 0.0022 0.0124 0.0124
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0038 0.0291 0.0605
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0226 0.035
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0129 0.1279 0.1279
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0014 0.0032 0.0043
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0578 0.0578
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0155 0.0328
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0127 0.0135
Trypanosoma cruzi DNA topoisomerase III, putative 0.0023 0.0133 0.0203
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0438 0.4613 1
Brugia malayi larval opioid receptor 0.005 0.0422 0.0659
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0574 0.09
Echinococcus granulosus apoptotic protease activating factor 1 0.0044 0.0355 0.0453
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0231 0.0248
Brugia malayi ecdysteroid receptor 0.0032 0.0231 0.0357
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0032 0.0032
Loa Loa (eye worm) neuropeptide F receptor 0.005 0.0422 0.0661
Schistosoma mansoni acetylcholinesterase 0.0024 0.0146 0.0146
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0015 0.0046 0.0065
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0049 0.0069
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0331 0.0769
Mycobacterium leprae Conserved hypothetical protein 0.0015 0.0046 0.0038
Schistosoma mansoni transient receptor potential channel 0.0014 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Brugia malayi nuclear receptor NHR-88 0.0032 0.0231 0.0357
Schistosoma mansoni neuropeptide receptor 0.005 0.0422 0.0422
Plasmodium vivax metacaspase 1, putative 0.0047 0.039 0.0616
Loa Loa (eye worm) thioredoxin reductase 0.0598 0.6329 1
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0072 0.0665 0.1386
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.0111 0.0117
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0438 0.4613 0.9754
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.0046 0.0066
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0293 0.0457
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0272 0.2823 1
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0016 0.006 0.0088
Loa Loa (eye worm) hypothetical protein 0.0047 0.039 0.061
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.0422 0.0458
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0172 0.0266
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0155 0.0328
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0078 0.0725 0.079
Plasmodium falciparum lysophospholipase, putative 0.0038 0.0291 0.0453
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0072 0.0665 0.0852
Trypanosoma cruzi DNA topoisomerase II, putative 0.0404 0.4238 0.6694
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.009
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0231 0.0755
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0153 0.1539 0.168
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0072 0.0665 0.0723
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0193 0.0298
Leishmania major mitochondrial DNA topoisomerase II 0.0479 0.505 0.7977
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0015 0.0046 0.0091
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0272 0.2823 0.446
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0088 0.0088
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0043 0.0346 0.0539
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0174 0.1757 0.2771
Echinococcus multilocularis caspase 3 0.0077 0.0715 0.0778
Loa Loa (eye worm) hypothetical protein 0.0039 0.0307 0.0479
Loa Loa (eye worm) hypothetical protein 0.0488 0.5149 0.8134
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0404 0.4238 0.6694
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0048 0.007
Schistosoma mansoni caspase-7 (C14 family) 0.0124 0.122 0.122
Brugia malayi Carboxylesterase family protein 0.0144 0.1432 0.2257
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0111 0.0169
Leishmania major DNA topoisomerase III, putative 0.0023 0.0133 0.0203
Schistosoma mansoni DNA helicase recq5 0.0021 0.0111 0.0111
Toxoplasma gondii hypothetical protein 0.0062 0.0558 0.0882
Schistosoma mansoni transient receptor potential channel 0.0014 0.0032 0.0032
Brugia malayi hypothetical protein 0.0173 0.1748 0.2756
Trypanosoma cruzi metacaspase, putative 0.0047 0.039 0.0609
Echinococcus multilocularis dnaJ subfamily B 0.0433 0.4554 0.498
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0369 0.0577
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0296 0.0632
Leishmania major cytochrome p450-like protein 0.0015 0.0046 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0266 0.0553
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0088 0.0088
Toxoplasma gondii heat shock protein 90, putative 0.0022 0.0124 0.0197
Echinococcus granulosus neuropeptide s receptor 0.0537 0.5674 0.7308
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0014 0.0032 0.0037
Leishmania major cytochrome p450-like protein 0.0024 0.0146 0.0224
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0161 0.0331
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.011 0.0116
Brugia malayi Carboxylesterase family protein 0.0144 0.1432 0.2257
Loa Loa (eye worm) hypothetical protein 0.0059 0.0517 0.0812
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0072 0.0665 0.1043
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0422 0.0539
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0291 0.0459
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0129 0.1279 0.1643
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0046 0.0055
Mycobacterium ulcerans glutamate synthase subunit beta 0.0072 0.0665 0.1433
Schistosoma mansoni 60S ribosomal protein L21 0.0017 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Schistosoma mansoni vesicular amine transporter 0.0014 0.0032 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0293 0.0609
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0131
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0182 0.1846 0.3964
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0015 0.0046 0.0091
Entamoeba histolytica ;Alias 0.0038 0.0291 0.0615
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0071 0.0071
Echinococcus granulosus acetylcholinesterase 0.0144 0.1432 0.1841
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0231 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0291 0.0605
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0072 0.0665 0.0852
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.0422 0.0539
Treponema pallidum NADH oxidase 0.0272 0.2823 0.8724
Plasmodium falciparum alpha/beta hydrolase, putative 0.0038 0.0291 0.0453
Schistosoma mansoni pyruvate dehydrogenase 0.0022 0.0124 0.0124
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0479 0.505 0.7977
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0057 0.0109
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0022 0.0124 0.0208
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0422 0.0458
Echinococcus granulosus dnaJ subfamily B 0.0433 0.4554 0.5865
Echinococcus granulosus caspase 0.0124 0.122 0.1567
Mycobacterium tuberculosis Possible lysophospholipase 0.0438 0.4613 0.7286
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0272 0.2823 0.4456
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0038 0.0291 0.0291
Trichomonas vaginalis 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0106 0.1025 0.2159
Loa Loa (eye worm) hypothetical protein 0.0017 0.0064 0.0095
Plasmodium vivax JmjC domain containing protein 0.0017 0.0064 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0266 0.0553
Schistosoma mansoni hypothetical protein 0.005 0.0422 0.0422
Loa Loa (eye worm) independent phosphoglycerate mutase isoform 2 0.0106 0.1025 0.1614
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.006 0.0095
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0072 0.0665 0.105
Schistosoma mansoni hypothetical protein 0.0044 0.0355 0.0355
Schistosoma mansoni voltage-gated cation channel 0.0129 0.1279 0.1279
Schistosoma mansoni voltage-gated ion channel 0.0014 0.0032 0.0032
Brugia malayi Pre-SET motif family protein 0.0221 0.2268 0.3578
Plasmodium vivax DNA repair protein REV1, putative 0.0011 0.0004 0.0007
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.005 0.005
Schistosoma mansoni amine GPCR 0.005 0.0422 0.0422
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0272 0.2823 0.3085
Mycobacterium tuberculosis Conserved protein 0.0022 0.0124 0.0189
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0022 0.0124 0.0208
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.0111 0.0138
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.0422 0.0458
Schistosoma mansoni peptidase 0.0038 0.0291 0.0291
Loa Loa (eye worm) hypothetical protein 0.0036 0.027 0.0421
Echinococcus granulosus sex peptide receptor 0.005 0.0422 0.0539
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0064 0.0064
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0088 0.0088
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0072 0.0665 0.105
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0495 0.0777
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Wolbachia endosymbiont of Brugia malayi phosphoglyceromutase 0.0106 0.1025 0.3604
Loa Loa (eye worm) hypothetical protein 0.0029 0.0193 0.0298
Trypanosoma brucei DNA topoisomerase III, putative 0.0023 0.0133 0.0203
Echinococcus granulosus somatostatin receptor 0.005 0.0422 0.0539
Loa Loa (eye worm) hypothetical protein 0.0022 0.0127 0.0194
Plasmodium falciparum thioredoxin reductase 0.0598 0.6329 1
Echinococcus multilocularis caspase 2 0.009 0.086 0.0937
Loa Loa (eye worm) carboxylesterase 0.0024 0.0146 0.0225
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.007
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0048 0.0068
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0038 0.0291 0.0605
Onchocerca volvulus 0.0032 0.0231 0.0755
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0272 0.2823 0.4456
Brugia malayi G protein-coupled receptor 0.005 0.0422 0.0659
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0422 0.0458
Onchocerca volvulus 0.0016 0.006 0.0185
Giardia lamblia Sgs1 DNA helicase, putative 0.0021 0.0111 0.0251
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0038 0.0291 0.0605
Plasmodium falciparum prodrug activation and resistance esterase 0.0038 0.0291 0.0453
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0115 0.0367
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0262 0.0407
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0032 0.0032
Plasmodium vivax glutathione reductase, putative 0.0598 0.6329 1
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0249 0.2568 0.7908
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0011 0.0005 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0266 0.0553
Loa Loa (eye worm) hypothetical protein 0.0025 0.0155 0.024
Echinococcus multilocularis fmrfamide receptor 0.005 0.0422 0.0458
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0578 0.0578
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0072 0.0665 0.1044
Entamoeba histolytica hypothetical protein 0.0038 0.0295 0.0625
Brugia malayi MAP kinase sur-1 0.0054 0.0466 0.0729
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0307 0.0713
Onchocerca volvulus 0.0024 0.0146 0.0472
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0064 0.0064
Schistosoma mansoni opsin-like receptor 0.005 0.0422 0.0422
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0578 0.074
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0065 0.0096
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0036 0.027 0.027
Brugia malayi intermediate filament protein 0.0029 0.0193 0.0296
Mycobacterium ulcerans ferredoxin reductase 0.0072 0.0665 0.1433
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0101
Mycobacterium ulcerans hypothetical protein 0.0072 0.0665 0.1433
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0049 0.0049
Trypanosoma cruzi trypanothione reductase, putative 0.0598 0.6329 1
Brugia malayi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0065 0.0583 0.0914
Trichomonas vaginalis mercuric reductase, putative 0.0272 0.2823 0.5965
Brugia malayi jmjC domain containing protein 0.0064 0.0575 0.0901
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0466 0.0977
Loa Loa (eye worm) endoplasmin 0.0022 0.0124 0.0191
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.005 0.0422 0.0661
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0307 0.0332
Brugia malayi DNA topoisomerase III 0.0023 0.0133 0.0202
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0015 0.0046 0.0091
Schistosoma mansoni glutamate synthase 0.0072 0.0665 0.0665
Schistosoma mansoni multidrug resistance protein 0.0011 0.0005 0.0005
Plasmodium vivax heat shock protein 86, putative 0.0022 0.0124 0.0197
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0014 0.0013
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0068 0.0101
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0231 0.0248
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0014 0.0032 0.0043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0422 0.0422
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0087 0.0131
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.039 0.0814
Loa Loa (eye worm) cytochrome P450 0.0015 0.0046 0.0067
Mycobacterium ulcerans DNA polymerase IV 0.0064 0.0574 0.1236
Echinococcus granulosus sodium channel protein 0.0051 0.0433 0.0553
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0029 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.0231 0.0359
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0038 0.0291 0.0453
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.0082 0.0086
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0014 0.0032 0.0043
Echinococcus granulosus caspase 2 0.009 0.086 0.1104
Schistosoma mansoni endoplasmin 0.0022 0.0124 0.0124
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0575 0.0575
Echinococcus multilocularis neuroligin 0.0024 0.0146 0.0156
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0307 0.0478
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0029 0.0051
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0036 0.027 0.0343
Schistosoma mansoni coup transcription factor 0.0032 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Echinococcus granulosus Phospholipase carboxylesterase 0.0038 0.0291 0.037
Brugia malayi hypothetical protein 0.0017 0.0068 0.0099
Mycobacterium ulcerans two component sensor kinase MprB 0.0022 0.0124 0.0261
Leishmania major hypothetical protein, conserved 0.0022 0.0124 0.019
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0046 0.0066
Chlamydia trachomatis DNA topoisomerase I 0.0023 0.0133 0.0454
Brugia malayi hypothetical protein 0.005 0.0422 0.0659
Loa Loa (eye worm) hypothetical protein 0.0025 0.0155 0.024
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0231 0.0357
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0015 0.0046 0.0065
Trypanosoma cruzi metacaspase, putative 0.0047 0.039 0.0609
Toxoplasma gondii hypothetical protein 0.0016 0.006 0.0095
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0072 0.0665 0.0723
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0014 0.0032 0.0043
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0072 0.0665 0.1433
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0231 0.0357
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0575 0.0575
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0038 0.0291 0.0453
Echinococcus multilocularis serotonin receptor 0.0183 0.1858 0.2029
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0182 0.0288
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0032 0.0031
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0049 0.0146
Trypanosoma brucei monoglyceride lipase, putative 0.0438 0.4613 0.7287
Plasmodium falciparum amino acid transporter, putative 0.0016 0.006 0.0089
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0231 0.0293
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0057 0.0057
Echinococcus granulosus bloom syndrome protein 0.0021 0.0111 0.0138
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0065 0.0103
Brugia malayi G protein-coupled receptor F59B2.13 0.005 0.0422 0.0659
Mycobacterium ulcerans oxygenase 0.0012 0.0012 0.0016
Schistosoma mansoni flap endonuclease-1 0.0025 0.0153 0.0153
Brugia malayi GnHR receptor homolog 0.005 0.0422 0.0659
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0099 0.0157
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0015 0.0046 0.0065
Echinococcus multilocularis sodium and chloride dependent glycine 0.0016 0.006 0.0062
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0099 0.0105
Schistosoma mansoni neuropeptide F-like receptor 0.005 0.0422 0.0422
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0266 0.0553
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0371 0.0587
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0226 0.035
Trichomonas vaginalis Ferredoxin 4 0.0012 0.0012 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0229 0.0474
Echinococcus multilocularis folate receptor beta 0.0108 0.1053 0.1149
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0065 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0029 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0231 0.0357
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0015 0.0046 0.0065
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0129 0.1279 0.1643
Schistosoma mansoni hypothetical protein 0.0072 0.0665 0.0665
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0231 0.0231
Echinococcus multilocularis caspase 0.0124 0.122 0.1331
Brugia malayi Transient-receptor-potential like protein 0.0014 0.0032 0.0043
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0005 0.0002
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0029 0.0028
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0072 0.0665 0.1396
Onchocerca volvulus Cell death protein 3 homolog 0.009 0.086 0.286
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0272 0.2823 0.3634
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0022 0.0124 0.0261
Schistosoma mansoni lipoxygenase 0.0087 0.0826 0.0826
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0072 0.0665 0.0852
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0014 0.0032 0.0043
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0068 0.0068
Echinococcus multilocularis acetylcholinesterase 0.0144 0.1432 0.1563
Echinococcus granulosus g protein coupled receptor 0.005 0.0422 0.0539
Loa Loa (eye worm) voltage-dependent calcium channel 0.0076 0.0706 0.111
Echinococcus multilocularis g protein coupled receptor 0.005 0.0422 0.0458
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0018 0.008 0.0126
Schistosoma mansoni nuclear receptor 0.0015 0.0048 0.0048
Plasmodium falciparum glutathione reductase 0.0272 0.2823 0.4456
Leishmania major mitochondrial DNA polymerase beta 0.032 0.3332 0.5262
Brugia malayi hypothetical protein 0.005 0.0422 0.0659
Mycobacterium ulcerans hypothetical protein 0.0025 0.0155 0.0328
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0231 0.0357
Schistosoma mansoni sulfide quinone reductase 0.0072 0.0665 0.0665
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.005 0.0422 0.0661
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0111 0.0224
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0278 0.0578
Echinococcus multilocularis lamin dm0 0.0029 0.0193 0.0207
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0129 0.1279 0.1279
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0087 0.0291
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0023 0.0133 0.021
Toxoplasma gondii endonuclease IV APN 0.0081 0.076 0.12
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.3221 0.6808
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0422 0.0422
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.005 0.0422 0.0539
Echinococcus granulosus 7TM GPCR rhodopsin 0.005 0.0422 0.0539
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0133 0.1322 0.1699
Schistosoma mansoni DNA polymerase eta 0.0036 0.027 0.027
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0032 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0015 0.0046 0.0065
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0129 0.1279 0.1643
Echinococcus multilocularis Phospholipase carboxylesterase 0.0038 0.0291 0.0314
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0306 0.0638
Entamoeba histolytica P-glycoprotein 5, putative 0.0011 0.0005 0.0011
Echinococcus multilocularis neuropeptide receptor 0.005 0.0422 0.0458
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0038 0.0291 0.0605
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0019 0.0088 0.0092
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0231 0.0231
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0155 0.0238
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0111 0.0175
Onchocerca volvulus 0.005 0.0422 0.1394
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.005 0.0422 0.0659
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0427 0.4487 0.5778
Trichomonas vaginalis receptor histidine kinase, putative 0.0022 0.0124 0.0253
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.009
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0014 0.0032 0.0032
Giardia lamblia GTOR 0.0048 0.0398 0.0927
Plasmodium falciparum epoxide hydrolase 2 0.0038 0.0291 0.0453
Echinococcus granulosus lamin dm0 0.0029 0.0193 0.0243
Mycobacterium ulcerans oxidoreductase 0.0012 0.0012 0.0016
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0022 0.0124 0.0189
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0014 0.0032 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0438 0.4613 0.9754
Trypanosoma cruzi adrenodoxin precursor, putative 0.0012 0.0012 0.0012
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Entamoeba histolytica hypothetical protein 0.0038 0.0295 0.0625
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0092 0.0874 0.1382
Schistosoma mansoni cpg binding protein 0.003 0.0213 0.0213
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.005 0.0422 0.0422
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.006 0.0095
Loa Loa (eye worm) multidrug resistance protein 3 0.0011 0.0005 0.0002
Entamoeba histolytica hypothetical protein 0.0038 0.0291 0.0615
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0022 0.0124 0.0261
Trichomonas vaginalis heat shock protein, putative 0.0022 0.0124 0.0253
Echinococcus multilocularis serotonin receptor 0.0183 0.1858 0.2029
Plasmodium vivax PST-A protein 0.0038 0.0291 0.0459
Echinococcus multilocularis sodium and chloride dependent glycine 0.0016 0.006 0.0062
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0022 0.0124 0.0132
Loa Loa (eye worm) hypothetical protein 0.0032 0.0231 0.0359
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0231 0.0357
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0014 0.0032 0.0044
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0012 0.0012 0.0024
Echinococcus granulosus hypothetical protein 0.005 0.0422 0.0539
Loa Loa (eye worm) neuropeptide F receptor 0.005 0.0422 0.0661
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.009
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0005 0.0001
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0064 0.0064
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0293 0.0457
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Echinococcus multilocularis dna polymerase kappa 0.0064 0.0574 0.0624
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0231 0.0248
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0029 0.0028
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0109 0.1057 0.2285
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0072 0.0665 0.1405
Echinococcus granulosus G protein coupled receptor 139 0.005 0.0422 0.0539
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0022 0.0124 0.04
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0019 0.0088 0.0109
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.0476 0.0745
Schistosoma mansoni hypothetical protein 0.005 0.0422 0.0422
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0057 0.0084
Giardia lamblia Thioredoxin reductase 0.0072 0.0665 0.1556
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0076 0.0112
Schistosoma mansoni ap endonuclease 0.002 0.0099 0.0099
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0033 0.0032
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.007
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0076 0.0112
Echinococcus multilocularis ryanodine receptor 44f 0.0014 0.0032 0.0031
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0022 0.0124 0.0261
Loa Loa (eye worm) hypothetical protein 0.0076 0.0706 0.111
Entamoeba histolytica 2,3-bisphosphoglycerate-independentphosphoglycerate mutase, putative 0.0058 0.0513 0.1084
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0146 0.0224
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0168
Schistosoma mansoni hypothetical protein 0.0433 0.4554 0.4554
Onchocerca volvulus Neuropeptide F receptor homolog 0.005 0.0422 0.1394
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.0082 0.0101
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0306 0.039
Echinococcus granulosus cpg binding protein 0.0032 0.0231 0.0293
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0155 0.0239
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0231 0.0231
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0014 0.0032 0.0043
Chlamydia trachomatis DNA gyrase subunit A 0.0092 0.0874 0.3085
Loa Loa (eye worm) TOPoisomerase family member 0.0427 0.4487 0.7087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0272 0.2823 0.4456
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0072 0.0665 0.1433
Trypanosoma cruzi heat shock protein 90, putative 0.0022 0.0124 0.019
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0032 0.0037
Plasmodium vivax DNA topoisomerase II, putative 0.0427 0.4487 0.7089
Brugia malayi ORL1-like opioid receptor 0.005 0.0422 0.0659
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0014 0.0032 0.0037
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.0556 0.0712
Schistosoma mansoni DNA helicase recq1 0.0021 0.0111 0.0111
Schistosoma mansoni DNA polymerase IV / kappa 0.0011 0.0004 0.0004
Echinococcus granulosus 7tm_1 domain containing protein 0.005 0.0422 0.0539
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0072 0.0665 0.1043
Loa Loa (eye worm) hypothetical protein 0.0158 0.159 0.2508
Schistosoma mansoni sulfide quinone reductase 0.0072 0.0665 0.0665
Entamoeba histolytica hypothetical protein 0.0038 0.0295 0.0625
Schistosoma mansoni inositol monophosphatase 0.0039 0.0306 0.0306
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.027 0.0419
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0182 0.1846 0.2911
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0023 0.0133 0.0204
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0029 0.0051
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0072 0.0665 0.1396
Leishmania major DNA topoisomerase ii 0.0404 0.4238 0.6694
Onchocerca volvulus 0.0012 0.0012 0.0023
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0307 0.0649
Schistosoma mansoni peptide (allatostatin)-like receptor 0.005 0.0422 0.0422
Mycobacterium ulcerans hypothetical protein 0.0168 0.1701 0.3681
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0048 0.0048
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0081 0.076 0.1194
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0022 0.0124 0.0253
Trypanosoma brucei DNA polymerase IV, putative 0.0064 0.0574 0.09
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Giardia lamblia NADH oxidase lateral transfer candidate 0.0272 0.2823 0.6644
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0172 0.0266
Onchocerca volvulus 0.0029 0.0193 0.0627
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0015 0.0046 0.0065
Trypanosoma brucei heat shock protein, putative 0.0022 0.0124 0.019
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.0046 0.0066
Loa Loa (eye worm) hypothetical protein 0.0158 0.159 0.2508
Echinococcus multilocularis sex peptide receptor 0.005 0.0422 0.0458
Echinococcus multilocularis musashi 0.0029 0.0193 0.0207
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0466 0.0506
Plasmodium falciparum thioredoxin reductase 0.0272 0.2823 0.4456
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.039 0.0814
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0.0032 0.0032
Echinococcus multilocularis neuropeptide receptor A26 0.0537 0.5674 0.6205
Chlamydia trachomatis DNA gyrase subunit B 0.0197 0.2005 0.7097
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.005 0.0422 0.0458
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0014 0.0032 0.0043
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0092 0.0874 0.2483
Trichomonas vaginalis Ferredoxin 3 0.0012 0.0012 0.0014
Entamoeba histolytica DNA topoisomerase III, putative 0.0023 0.0133 0.0281
Schistosoma mansoni biogenic amine receptor 0.005 0.0422 0.0422
Entamoeba histolytica hypothetical protein 0.0038 0.0295 0.0625
Brugia malayi Inositol-1 0.0039 0.0306 0.0476
Schistosoma mansoni ryanodine receptor related 0.0014 0.0032 0.0032
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0064 0.0094
Toxoplasma gondii esterase/lipase/thioesterase domain-containing protein 0.0038 0.0291 0.0459
Mycobacterium leprae Probable two component sensor kinase MprB 0.0022 0.0124 0.0208
Entamoeba histolytica P-glyco protein 6, putative 0.0011 0.0005 0.0011
Brugia malayi Cytochrome P450 family protein 0.0015 0.0046 0.0065
Trypanosoma brucei 2,3-bisphosphoglycerate-independent phosphoglycerate mutase-like protein, putative 0.0017 0.0071 0.0106
Loa Loa (eye worm) RecQ helicase 0.0021 0.0111 0.0169
Schistosoma mansoni hypothetical protein 0.0014 0.0032 0.0032
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0072 0.0665 0.0723
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0466 0.0977
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0021 0.0111 0.0169
Echinococcus multilocularis orexin receptor type 2 0.005 0.0422 0.0458
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0032 0.0037
Schistosoma mansoni neuropeptide receptor 0.005 0.0422 0.0422
Chlamydia trachomatis thioredoxin reductase 0.0072 0.0665 0.2341
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0015 0.0046 0.0091
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0043 0.0346 0.0538
Brugia malayi Serotonin/octopamine receptor family protein 7 0.005 0.0422 0.0659
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0155 0.0328
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0233 0.025
Mycobacterium tuberculosis Possible two component sensor kinase 0.0022 0.0124 0.0189
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.011 0.0167
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0466 0.0596
Loa Loa (eye worm) hypothetical protein 0.0059 0.0517 0.0812
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0036 0.027 0.0292
Toxoplasma gondii hypothetical protein 0.0449 0.4729 0.7472
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.0111 0.0138
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0306 0.0331
Brugia malayi hypothetical protein 0.0014 0.0032 0.0043
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0151 0.1516 0.2391
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0048 0.0068
Onchocerca volvulus 0.0096 0.092 0.306
Echinococcus multilocularis g-protein coupled receptor 0.005 0.0422 0.0458
Echinococcus granulosus abhydrolase domain containing 3 0.0038 0.0291 0.037
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0081 0.076 0.12
Leishmania major NADH dehydrogenase, putative 0.0072 0.0665 0.1044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0398 0.0831
Trypanosoma cruzi adrenodoxin precursor, putative 0.0012 0.0012 0.0012
Brugia malayi glutathione reductase 0.0598 0.6329 1
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0022 0.0124 0.0189
Trichomonas vaginalis DNA polymerase eta, putative 0.0064 0.0574 0.1204
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0036 0.0269 0.0936
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0048 0.0068
Loa Loa (eye worm) hypothetical protein 0.0038 0.0291 0.0454
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0032 0.0037
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0087 0.0129
Schistosoma mansoni hypothetical protein 0.0015 0.0049 0.0049
Echinococcus granulosus g protein coupled receptor 0.005 0.0422 0.0539
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0032 0.0037
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0556 0.0556
Schistosoma mansoni hypothetical protein 0.0109 0.1066 0.1066
Echinococcus granulosus hypothetical protein 0.0014 0.0032 0.0037
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0072 0.0665 0.1396
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0233 0.0233
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0072 0.0665 0.1043
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0182 0.0281
Plasmodium falciparum lysophospholipase, putative 0.0438 0.4613 0.7287
Brugia malayi Protein kinase domain containing protein 0.0016 0.0054 0.0078
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.039 0.0814
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0022 0.0124 0.008
Plasmodium falciparum esterase, putative 0.0438 0.4613 0.7287
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0023 0.0133 0.0431
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.005 0.0422 0.0458
Plasmodium vivax DNA gyrase subunit A, putative 0.0092 0.0874 0.1382
Plasmodium vivax DNA gyrase subunit B, putative 0.0249 0.2568 0.4058
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.005 0.0422 0.0422
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0014 0.0032 0.0043
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.0422 0.0539
Schistosoma mansoni rab6-interacting 0.0021 0.011 0.011
Schistosoma mansoni single-minded 0.0051 0.044 0.044
Brugia malayi cytochrome P450 0.0015 0.0046 0.0065
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0307 0.0639
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0665 0.1044
Echinococcus granulosus sodium and chloride dependent glycine 0.0016 0.006 0.0073
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0172 0.0266
Mycobacterium ulcerans hypothetical protein 0.006 0.0528 0.1136
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0065 0.0065
Leishmania major hypothetical protein, conserved 0.0072 0.0665 0.1044
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0369 0.0577
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0023 0.0133 0.0203
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0048 0.0048
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0048 0.0057
Echinococcus multilocularis caspase 8 0.0047 0.039 0.0422
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0438 0.4613 0.9754
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0306 0.0477
Onchocerca volvulus 0.0038 0.0296 0.0972
Schistosoma mansoni sodium/chloride dependent transporter 0.0016 0.006 0.006
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.039 0.0814
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0111 0.0167
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0038 0.0291 0.0459
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0398 0.0398
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0022 0.0124 0.0261
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0231 0.0357
Leishmania major DNA topoisomerase III, putative 0.0023 0.0133 0.0203
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0002
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0019 0.0088 0.0092
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0088 0.0176
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.039 0.0814
Trypanosoma brucei DNA topoisomerase ii 0.0479 0.505 0.7977
Trypanosoma brucei unspecified product 0.0025 0.0151 0.0231
Loa Loa (eye worm) programmed cell death 8 0.0072 0.0665 0.1045
Trypanosoma brucei developmentally regulated phosphoprotein 0.0022 0.0124 0.019
Echinococcus multilocularis rho GTPase activating protein 20 0.0023 0.0133 0.0141
Leishmania major hypothetical protein, conserved 0.0072 0.0665 0.1044
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0129 0.1279 0.1395
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0111 0.0117
Trypanosoma brucei heat shock protein, putative 0.0022 0.0124 0.019
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0422 0.0458
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0466 0.0977
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0398 0.0431
Brugia malayi conserved hypotetical protein 0.0015 0.0048 0.0068
Plasmodium vivax hypothetical protein, conserved 0.0016 0.006 0.0095
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Trichomonas vaginalis glutathione reductase, putative 0.0272 0.2823 0.5965
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0022 0.0124 0.0261
Brugia malayi Carboxylesterase family protein 0.0024 0.0146 0.0223
Trypanosoma brucei heat shock protein, putative 0.0022 0.0124 0.019
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0155 0.0239
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0065 0.0103
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0574 0.09
Echinococcus multilocularis biogenic amine (5HT) receptor 0.005 0.0422 0.0458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0191 0.0394
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0005 0.0002
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0022 0.0124 0.0253
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0016 0.006 0.0062
Mycobacterium tuberculosis Probable oxidoreductase 0.0382 0.4005 0.6324
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0182 0.0281
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0422 0.0458
Schistosoma mansoni hypothetical protein 0.0021 0.011 0.011
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0023 0.0133 0.0271
Brugia malayi hypothetical protein 0.0017 0.0068 0.0099
Echinococcus multilocularis muscleblind protein 1 0.0158 0.159 0.1736
Leishmania major hypothetical protein, conserved 0.0072 0.0665 0.1044
Echinococcus granulosus alpha 1A adrenergic receptor 0.005 0.0422 0.0539
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0029 0.0033
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0155 0.0238
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0015 0.0046 0.0065
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0231 0.0248
Loa Loa (eye worm) hypothetical protein 0.0488 0.5149 0.8134
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0029 0.0051
Trypanosoma brucei metacaspase 0.0047 0.039 0.0609
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0005 0.0002
Treponema pallidum DNA topoisomerase I (topA) 0.0023 0.0133 0.0108
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0087 0.0137
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0065 0.0096
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Trypanosoma cruzi Serine peptidase, Clan SC, Family S09X, putative 0.0038 0.0291 0.0453
Loa Loa (eye worm) voltage-gated potassium channel 0.0014 0.0032 0.0045
Leishmania major metacaspase, putative 0.0047 0.039 0.0609
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0307 0.0639
Chlamydia trachomatis DNA gyrase subunit A 0.0092 0.0874 0.3085
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0346 0.0539
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0296 0.032
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.039 0.0814
Leishmania major DNA topoisomerase 1A 0.0023 0.0133 0.0203
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0575 0.0903
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0022 0.0124 0.0197
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0048 0.0057
Schistosoma mansoni ap endonuclease 0.002 0.0099 0.0099
Chlamydia trachomatis acyltransferase family protein 0.0038 0.0291 0.1014
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0057 0.0058
Loa Loa (eye worm) hypothetical protein 0.0289 0.2999 0.4735
Toxoplasma gondii phospholipase 0.0038 0.0291 0.0459
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0427 0.4487 0.7086
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0022 0.0124 0.0189
Schistosoma mansoni zinc finger protein 0.0015 0.0048 0.0048
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0064 0.0095
Toxoplasma gondii DNA topoisomerase family protein 0.0023 0.0133 0.021
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0049 0.0049
Onchocerca volvulus 0.005 0.0422 0.1394
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0578 0.0628
Loa Loa (eye worm) hypothetical protein 0.0072 0.0665 0.1045
Mycobacterium ulcerans electron transfer protein 0.0012 0.0012 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0272 0.2823 0.4456
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0064 0.0066
Trichomonas vaginalis apoptosis inducing factor, putative 0.0072 0.0665 0.1396
Loa Loa (eye worm) hypothetical protein 0.0038 0.0291 0.0454
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0048 0.0048
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.027 0.042
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0022 0.0124 0.0189
Plasmodium vivax lysophospholipase, putative 0.0038 0.0291 0.0459
Schistosoma mansoni adrenodoxin 0.0012 0.0012 0.0012
Trypanosoma brucei trypanothione reductase 0.0598 0.6329 1
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0072 0.0665 0.1405
Schistosoma mansoni hypothetical protein 0.0015 0.0046 0.0046
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0024 0.0146 0.0156
Schistosoma mansoni multidrug resistance protein 0.0011 0.0005 0.0005
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0072 0.0665 0.1044
Echinococcus granulosus single minded 2 0.0042 0.0334 0.0426
Echinococcus granulosus dro:myosuppressin receptor 0.005 0.0422 0.0539
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0072 0.0665 0.1433
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0048 0.0048
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0005 0.0002
Brugia malayi MGC83647 protein 0.0038 0.0291 0.0452
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0048 0.0068
Trypanosoma cruzi trypanothione reductase, putative 0.0272 0.2823 0.4456
Mycobacterium ulcerans hypothetical protein 0.0438 0.4613 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0291 0.0454
Plasmodium falciparum esterase, putative 0.0449 0.4729 0.747
Brugia malayi Cytochrome P450 family protein 0.0024 0.0146 0.0223
Onchocerca volvulus 0.005 0.0422 0.1394
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0099 0.02
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0049 0.0049
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0404 0.4238 0.6694
Schistosoma mansoni gliotactin 0.0024 0.0146 0.0146
Toxoplasma gondii ferodoxin FD 0.0012 0.0012 0.0019
Toxoplasma gondii thioredoxin reductase 0.0598 0.6329 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0231 0.0357
Plasmodium falciparum esterase, putative 0.0449 0.4729 0.747
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0017 0.0071 0.0106
Giardia lamblia Cgi67 serine protease precursor-like protein 0.0038 0.0291 0.0675
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0032 0.0032
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0048 0.0068
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0146 0.0224
Echinococcus multilocularis neuropeptide s receptor 0.0537 0.5674 0.6205
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.009
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0272 0.2823 0.4456
Loa Loa (eye worm) hypothetical protein 0.0144 0.1432 0.2259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0323 0.0672
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0092 0.0874 0.3068
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.005 0.0422 0.1394
Plasmodium falciparum heat shock protein 90 0.0022 0.0124 0.019
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0272 0.2823 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0187 0.029
Echinococcus granulosus monoacylglycerol lipase abhd12 0.0038 0.0291 0.037
Trichomonas vaginalis Ferredoxin 7 0.0012 0.0012 0.0014
Onchocerca volvulus 0.0025 0.0155 0.0503
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.005 0.0422 0.0422
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0012 0.0012 0.0012
Schistosoma mansoni amine GPCR 0.005 0.0422 0.0422
Trichomonas vaginalis 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0017 0.0071 0.014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0422 0.0422
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0173 0.175 0.3788
Schistosoma mansoni histamine h1 receptor 0.005 0.0422 0.0422
Schistosoma mansoni intermediate filament proteins 0.0029 0.0193 0.0193
Schistosoma mansoni voltage-dependent calcium channel 0.0014 0.0032 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0057 0.0109
Brugia malayi hypothetical protein 0.0024 0.0146 0.0223
Plasmodium falciparum alpha/beta hydrolase, putative 0.0038 0.0291 0.0453
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0064 0.0094
Schistosoma mansoni transient receptor potential channel 4 0.0014 0.0032 0.0032
Schistosoma mansoni heat shock protein 0.0022 0.0124 0.0124
Echinococcus granulosus muscleblind protein 0.0158 0.159 0.2044
Trypanosoma brucei heat shock protein, putative 0.0022 0.0124 0.019
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0047
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.005 0.0422 0.0458
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0146 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0293 0.0609
Onchocerca volvulus 0.005 0.0422 0.1394
Leishmania major trypanothione reductase 0.0598 0.6329 1
Echinococcus multilocularis calcium activated potassium channel 0.0014 0.0038 0.0037
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0072 0.0665 0.1405
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0371 0.0474
Plasmodium vivax multidrug resistance protein 1, putative 0.0011 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0131
Brugia malayi Pre-SET motif family protein 0.0032 0.0233 0.036
Echinococcus granulosus Ankyrin 0.0015 0.005 0.006
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0272 0.2823 0.4456
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0115 0.0174
Trypanosoma cruzi heat shock protein 85, putative 0.0022 0.0124 0.019
Brugia malayi Carboxylesterase family protein 0.0024 0.0146 0.0223
Plasmodium vivax ferredoxin, putative 0.0012 0.0012 0.0019
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0016 0.006 0.009
Echinococcus multilocularis sodium channel protein 0.0051 0.0433 0.047
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0029 0.0039
Echinococcus granulosus thyrotropin releasing hormone receptor 0.005 0.0422 0.0539
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0048 0.0144
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0231 0.0359
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Echinococcus granulosus two pore calcium channel protein 2 0.0014 0.0032 0.0037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0231 0.0248
Leishmania major protein kinase, putative 0.0014 0.0034 0.0047
Plasmodium falciparum lysophospholipase, putative 0.0438 0.4613 0.7287
Mycobacterium tuberculosis Probable reductase 0.0182 0.1846 0.2911
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.007
Trypanosoma cruzi heat shock protein 85, putative 0.0022 0.0124 0.019
Treponema pallidum quinoline 2-oxidoreductase 0.0058 0.0513 0.1324
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0272 0.2823 0.446
Loa Loa (eye worm) STAT protein 0.0139 0.1386 0.2185
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0151 0.1515 0.2387
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0466 0.073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0022 0.0037
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0012 0.0012 0.0019
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0016 0.006 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0422 0.0422
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0022 0.0124 0.0189
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0038 0.0291 0.0291
Loa Loa (eye worm) hypothetical protein 0.0129 0.1279 0.2016
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0064 0.0101
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0.0004 0.0007
Echinococcus granulosus RUN 0.0021 0.011 0.0137
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0291 0.0459
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0012 0.0012 0.0009
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0068 0.007
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0293 0.0457
Schistosoma mansoni multidrug resistance protein 0.0011 0.0005 0.0005
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0231 0.0293
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0422 0.0458
Echinococcus granulosus lamin 0.0029 0.0193 0.0243
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Echinococcus multilocularis neuropeptides capa receptor 0.005 0.0422 0.0458
Loa Loa (eye worm) hypothetical protein 0.0183 0.1858 0.2931
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0088 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0266 0.0553
Schistosoma mansoni two-pore calcium channel 0.0014 0.0032 0.0032
Echinococcus multilocularis 0.0015 0.0046 0.0047
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.027 0.0419
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0331 0.0516
Toxoplasma gondii ferredoxin, putative 0.0012 0.0012 0.0019
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0272 0.2823 0.4456
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0057 0.0068
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0015 0.0046 0.0065
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.039 0.0814
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0072 0.0665 0.1433
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0072 0.0665 0.105
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0012 0.0012
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.011 0.0137
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0032 0.0032
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0065 0.0584 0.0916
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0051 0.0433 0.0553
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0032 0.0032
Leishmania major ferredoxin, 2fe-2s-like protein 0.0012 0.0012 0.0012
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0213 0.033
Loa Loa (eye worm) acetylcholinesterase 1 0.0144 0.1432 0.2259
Loa Loa (eye worm) heat shock protein 90 0.0022 0.0124 0.0191
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0024 0.0146 0.0223
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.039 0.0814
Trichomonas vaginalis DNA topoisomerase II, putative 0.0427 0.4487 0.9487
Echinococcus multilocularis BC026374 protein (S09 family) 0.0024 0.0146 0.0156
Loa Loa (eye worm) hypothetical protein 0.0038 0.0291 0.0454
Echinococcus granulosus death domain containing protein 0.0015 0.0049 0.0058
Echinococcus multilocularis apoptotic protease activating factor 1 0.0044 0.0355 0.0384
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0288 0.2995 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0072 0.0665 0.1396
Entamoeba histolytica hypothetical protein 0.0038 0.0291 0.0615
Brugia malayi neuropeptide F receptor 0.005 0.0422 0.0659
Echinococcus granulosus g-protein coupled receptor 0.005 0.0422 0.0539
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0022 0.0124 0.0261
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0099 0.0151
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0578 0.1244
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0022 0.0124 0.0189
Loa Loa (eye worm) hypothetical protein 0.0096 0.092 0.1448
Trichomonas vaginalis conserved hypothetical protein 0.0449 0.4729 1
Loa Loa (eye worm) DR-78 0.0015 0.0048 0.007
Loa Loa (eye worm) hypothetical protein 0.0014 0.0034 0.0048
Loa Loa (eye worm) hypothetical protein 0.0096 0.092 0.1448
Echinococcus multilocularis microtubule associated protein 2 0.073 0.7763 0.8491
Brugia malayi DNA topoisomerase III beta-1 0.0023 0.0133 0.0202
Giardia lamblia DNA topoisomerase II 0.0404 0.4247 1
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0072 0.0665 0.1405
Leishmania major hypothetical protein, conserved 0.0017 0.0064 0.0094
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0064 0.0066
Brugia malayi Uncoordinated protein 44 0.0015 0.0049 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0226 0.035
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0272 0.2823 0.4456
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0124 0.122 0.1922
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0293 0.3048 0.4812
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0124 0.122 0.2638
Loa Loa (eye worm) hypothetical protein 0.0021 0.0111 0.0169
Echinococcus granulosus abhydrolase domain containing protein 13 0.0038 0.0291 0.037
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0015 0.0046 0.0065
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0015 0.0046 0.0065
Echinococcus granulosus caspase 3 0.0077 0.0715 0.0917
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0188 0.0388
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0025 0.0155 0.024
Entamoeba histolytica P-glycoprotein-2, putative 0.0011 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0336 0.3506 0.5537
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0125 0.1231 0.1582
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Brugia malayi jmjC domain containing protein 0.0017 0.0064 0.0093
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0466 0.0977
Schistosoma mansoni thyroid hormone receptor 0.0165 0.1668 0.1668
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.039 0.0814
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0308 0.048
Brugia malayi gonadotropin-releasing hormone receptor 2 0.005 0.0422 0.0659
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.005 0.0422 0.0422
Giardia lamblia DINP protein human, muc B family 0.0043 0.0346 0.0804
Brugia malayi Death domain containing protein 0.0015 0.0049 0.0069
Loa Loa (eye worm) hypothetical protein 0.005 0.0422 0.0661
Echinococcus multilocularis neuropeptide Y receptor 0.005 0.0422 0.0458
Trichomonas vaginalis Ferredoxin 2 0.0012 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0231 0.0359
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0466 0.0731
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0016 0.006 0.006
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0081 0.076 0.1594
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0022 0.0124 0.019
Loa Loa (eye worm) hypothetical protein 0.0173 0.1748 0.2757
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0015 0.0046 0.0065
Brugia malayi hypothetical protein 0.005 0.0422 0.0659
Leishmania major protein kinase, putative 0.0019 0.009 0.0135
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0029 0.0033
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0115 0.0174
Toxoplasma gondii hypothetical protein 0.0038 0.0291 0.0459
Loa Loa (eye worm) hypothetical protein 0.0059 0.0517 0.0812
Toxoplasma gondii protein c14orf29, putative 0.0038 0.0291 0.0459
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0574 0.09
Echinococcus multilocularis neuropeptides capa receptor 0.005 0.0422 0.0458
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0367 0.3841 0.812
Mycobacterium ulcerans epimerase 0.0021 0.0115 0.024
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0023 0.0133 0.0133
Trypanosoma brucei metacaspase 5, putative 0.0047 0.039 0.0609
Toxoplasma gondii hypothetical protein 0.0016 0.006 0.0095
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0427 0.4487 0.4906
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0449 0.4729 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0064 0.0095
Brugia malayi G-protein coupled receptor 0.005 0.0422 0.0659
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0032 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0422 0.0422
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.0422 0.0422
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0005 0.0002
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0068 0.0099
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0012 0.0012 0.0011
Plasmodium vivax alpha/beta hydrolase, putative 0.0038 0.0291 0.0459
Echinococcus granulosus Adrenodoxin mitochondrial 0.0012 0.0012 0.001
Echinococcus granulosus neuropeptide Y receptor 0.005 0.0422 0.0539
Leishmania major heat shock protein 83-1 0.0022 0.0124 0.019
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0155 0.0328
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0038 0.0291 0.0605
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0584 0.1257
Schistosoma mansoni sodium-dependent amino acid transporter 0.0016 0.006 0.006
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.005 0.0422 0.0422
Mycobacterium ulcerans DNA topoisomerase I 0.0023 0.0133 0.0279
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0034 0.0033
Brugia malayi isocitrate dehydrogenase 0.0017 0.0065 0.0095
Onchocerca volvulus 0.0016 0.006 0.0185
Onchocerca volvulus 0.005 0.0422 0.1394
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0155 0.0238
Loa Loa (eye worm) hypothetical protein 0.0024 0.0146 0.0225
Schistosoma mansoni lipoxygenase 0.0125 0.1231 0.1231
Echinococcus multilocularis carboxylesterase 5A 0.0144 0.1432 0.1563
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0231 0.0357
Brugia malayi STAT protein, DNA binding domain containing protein 0.0139 0.1386 0.2184
Brugia malayi putative neuropeptide receptor NPR1 0.005 0.0422 0.0659
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.005 0.0422 0.0422
Onchocerca volvulus 0.005 0.0422 0.1394
Loa Loa (eye worm) hypothetical protein 0.0039 0.0308 0.0481
Leishmania major developmentally regulated phosphoprotein-like protein 0.0022 0.0124 0.019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0064 0.0574 0.09
Brugia malayi ion channel NompC 0.0014 0.0032 0.0043
Echinococcus multilocularis tachykinin peptides receptor 99D 0.005 0.0422 0.0458
Brugia malayi follicle stimulating hormone receptor 0.0293 0.3048 0.4811
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0231 0.0357
Loa Loa (eye worm) hypothetical protein 0.0014 0.0032 0.0045
Loa Loa (eye worm) G-protein coupled receptor 0.005 0.0422 0.0661
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0022 0.0124 0.0189
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0111 0.0169
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0231 0.0755
Echinococcus granulosus carboxylesterase 5A 0.0144 0.1432 0.1841
Brugia malayi Dopamine receptor protein 1 0.005 0.0422 0.0659

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 3 % Inhibitory activity of the compound against thrombin at concentration 400 nM ChEMBL. 12668009
Inhibition (binding) = 3 % Inhibitory activity of the compound against thrombin at concentration 400 nM ChEMBL. 12668009

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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