Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | purine nucleoside phosphorylase (deoD) | 0.0054 | 0.0464 | 0.6332 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0254 | 0.1687 |
Echinococcus granulosus | uridine phosphorylase 1 | 0.0054 | 0.0464 | 0.0462 |
Plasmodium falciparum | thioredoxin reductase | 0.0033 | 0.0254 | 0.1687 |
Echinococcus granulosus | dnaJ subfamily B | 0.0416 | 0.4207 | 0.4206 |
Brugia malayi | Pre-SET motif family protein | 0.0424 | 0.4286 | 0.922 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0417 | 0.0988 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0009 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0015 | 0.0061 | 0.0061 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0107 | 0.0253 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.2583 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0107 | 0.0709 |
Giardia lamblia | 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase | 0.0054 | 0.0464 | 0.1794 |
Echinococcus multilocularis | bloom syndrome protein | 0.0064 | 0.0566 | 0.0565 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0033 | 0.0254 | 0.1687 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.0054 | 0.0464 | 0.1099 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0154 | 0.1499 | 0.704 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.0731 | 0.073 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0038 | 0.0303 | 0.0302 |
Onchocerca volvulus | 0.0061 | 0.0543 | 0.1111 | |
Chlamydia trachomatis | dihydrofolate reductase | 0.0045 | 0.037 | 0.5053 |
Trypanosoma brucei | methylthioadenosine phosphorylase, putative | 0.0054 | 0.0464 | 0.3087 |
Entamoeba histolytica | recQ family helicase, putative | 0.0019 | 0.0102 | 0.2191 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0013 | 0.0043 | 0.0042 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0416 | 0.4207 | 0.4206 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0045 | 0.037 | 0.0369 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0019 | 0.011 | 0.0727 |
Brugia malayi | hypothetical protein | 0.0124 | 0.1189 | 0.2557 |
Brugia malayi | Hypothetical 29.7 kDa protein C05D11.5 in chromosome III | 0.0021 | 0.0122 | 0.0262 |
Leishmania major | trypanothione reductase | 0.0096 | 0.0903 | 0.4237 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0107 | 0.0709 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0121 | 0.1162 | 0.1162 |
Plasmodium falciparum | thioredoxin reductase | 0.0096 | 0.0903 | 0.6018 |
Brugia malayi | dihydrofolate reductase family protein | 0.0045 | 0.037 | 0.0796 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0009 | 0.0001 | 0.0002 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0033 | 0.0254 | 0.346 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0033 | 0.0254 | 0.1687 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0244 | 0.2427 | 0.9393 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.2583 |
Onchocerca volvulus | Putative hydroxypyruvate isomerase | 0.0021 | 0.0122 | 0.0249 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.004 | 0.0319 | 0.212 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.005 | 0.0421 | 0.0998 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0107 | 0.0107 |
Onchocerca volvulus | Netrin receptor homolog | 0.0015 | 0.0061 | 0.0124 |
Toxoplasma gondii | phosphorylase family protein | 0.0054 | 0.0464 | 0.2173 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0027 | 0.0193 | 0.128 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0229 | 0.0228 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0009 | 0.0001 | 0.0002 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0058 | 0.0512 | 0.198 |
Schistosoma mansoni | dihydrofolate reductase | 0.0045 | 0.037 | 0.0877 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.0731 | 0.073 |
Onchocerca volvulus | 0.0109 | 0.1039 | 0.2124 | |
Loa Loa (eye worm) | uridine phosphorylase | 0.0054 | 0.0464 | 0.0464 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0013 | 0.0043 | 0.0277 |
Entamoeba histolytica | recQ family DNA helicase | 0.0019 | 0.011 | 0.2355 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0107 | 0.0499 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0013 | 0.0043 | 0.0087 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0064 | 0.0566 | 0.1217 |
Echinococcus granulosus | lamin dm0 | 0.0055 | 0.0476 | 0.0475 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0009 | 0.0008 | 0.0016 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.2583 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0107 | 0.0253 |
Schistosoma mansoni | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.6141 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.011 | 0.011 |
Brugia malayi | hypothetical protein | 0.0166 | 0.1624 | 0.3495 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 0.0948 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0026 | 0.0025 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.0054 | 0.0464 | 0.1099 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0254 | 0.1188 |
Schistosoma mansoni | netrin receptor unc5 | 0.0015 | 0.0061 | 0.0142 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0013 | 0.0043 | 0.0042 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0241 | 0.2394 | 0.2393 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0033 | 0.0254 | 0.0519 |
Schistosoma mansoni | tyrosine/tryptophan monooxygenase | 0.0215 | 0.2129 | 0.5059 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.008 | 0.0731 | 0.2828 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0254 | 0.1687 |
Mycobacterium ulcerans | epimerase | 0.0021 | 0.0122 | 0.0471 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh1 | 0.0009 | 0.0001 | 0.0004 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0459 | 0.4649 | 0.4649 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0043 | 0.0087 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0109 | 0.1039 | 0.402 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0052 | 0.0447 | 0.1729 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.2583 |
Echinococcus granulosus | thymidylate synthase | 0.0109 | 0.1039 | 0.1038 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0019 | 0.011 | 0.0727 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0001 | 0.0001 |
Trichomonas vaginalis | set domain proteins, putative | 0.0483 | 0.489 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0416 | 0.4207 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0009 | 0.0001 | 0.0004 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0038 | 0.0303 | 0.0302 |
Trichomonas vaginalis | purine nucleoside phosphorylase I, putative | 0.0259 | 0.2584 | 0.5284 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0038 | 0.0298 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.0323 | 0.3243 | 0.3243 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0107 | 0.0709 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0013 | 0.0043 | 0.0568 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.2583 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0013 | 0.0043 | 0.0277 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.1624 | 0.1624 |
Mycobacterium leprae | PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) | 0.0078 | 0.0715 | 0.2764 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0033 | 0.0254 | 0.0253 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0241 | 0.2394 | 0.2393 |
Mycobacterium ulcerans | NADH dehydrogenase | 0.0009 | 0.0001 | 0.0004 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0052 | 0.0447 | 0.2976 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0038 | 0.0298 | 0.198 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0033 | 0.0254 | 0.0982 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0038 | 0.0303 | 0.0303 |
Echinococcus granulosus | methylthioadenosine phosphorylase | 0.0054 | 0.0464 | 0.0462 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.169 | 0.4016 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0154 | 0.1499 | 1 |
Giardia lamblia | Thioredoxin reductase | 0.0009 | 0.0001 | 0.0004 |
Echinococcus multilocularis | thymidylate synthase | 0.0109 | 0.1039 | 0.1038 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0052 | 0.0448 | 0.1732 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0219 | 0.2174 | 0.8416 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0731 | 0.2831 |
Mycobacterium leprae | Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) | 0.0259 | 0.2584 | 1 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0033 | 0.0254 | 0.0253 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0038 | 0.0303 | 0.0651 |
Entamoeba histolytica | MTA/SAH nucleosidase, putative | 0.0054 | 0.0464 | 1 |
Echinococcus granulosus | single minded 2 | 0.0037 | 0.0288 | 0.0287 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprB | 0.0009 | 0.0001 | 0.0004 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0033 | 0.0254 | 0.0982 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0013 | 0.0043 | 0.0042 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.0193 | 0.2626 |
Schistosoma mansoni | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.6141 |
Toxoplasma gondii | phosphorylase family protein | 0.0054 | 0.0464 | 0.2173 |
Leishmania major | nucleoside phosphorylase-like protein | 0.0054 | 0.0464 | 0.2173 |
Brugia malayi | PAS domain containing protein | 0.005 | 0.0421 | 0.0905 |
Echinococcus granulosus | lamin | 0.0055 | 0.0476 | 0.0475 |
Loa Loa (eye worm) | hypothetical protein | 0.0241 | 0.2394 | 0.2394 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0058 | 0.0512 | 0.198 |
Mycobacterium ulcerans | dehydrogenase | 0.0009 | 0.0001 | 0.0004 |
Mycobacterium ulcerans | ferredoxin reductase | 0.0009 | 0.0001 | 0.0004 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0153 | 0.1492 | 0.1492 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0013 | 0.0043 | 0.0042 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0038 | 0.0303 | 0.1171 |
Toxoplasma gondii | aromatic amino acid hydrolase AAH2 | 0.0215 | 0.2129 | 1 |
Brugia malayi | intermediate filament protein | 0.0055 | 0.0476 | 0.1024 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0009 | 0.0001 | 0.0002 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0424 | 0.4286 | 0.4286 |
Brugia malayi | DNA-(Apurinic or apyrimidinic site) lyase | 0.0078 | 0.0715 | 0.1538 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0013 | 0.0043 | 0.0087 |
Trypanosoma brucei | uridine phosphorylase | 0.0054 | 0.0464 | 0.3087 |
Onchocerca volvulus | 0.0037 | 0.0288 | 0.0589 | |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0058 | 0.0512 | 0.051 |
Onchocerca volvulus | 0.0013 | 0.0043 | 0.0087 | |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0244 | 0.2427 | 0.9394 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0038 | 0.0298 | 0.0609 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0038 | 0.0298 | 0.0297 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 1 |
Brugia malayi | Death domain containing protein | 0.0015 | 0.0061 | 0.0131 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0061 | 0.0543 | 0.0542 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0052 | 0.0447 | 0.0914 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 0.0948 |
Schistosoma mansoni | DNA helicase recq5 | 0.0038 | 0.0303 | 0.0717 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0219 | 0.2174 | 0.8416 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0009 | 0.0001 | 0.0002 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0109 | 0.1039 | 0.2467 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0013 | 0.0043 | 0.0277 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0254 | 0.1687 |
Schistosoma mansoni | single-minded | 0.005 | 0.0421 | 0.0998 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0033 | 0.0254 | 0.1687 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0543 | 0.1289 |
Mycobacterium leprae | Possible regulatory protein | 0.0013 | 0.0043 | 0.0161 |
Echinococcus multilocularis | musashi | 0.0055 | 0.0476 | 0.0475 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0731 | 1 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0107 | 0.0499 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0303 | 0.0303 |
Echinococcus granulosus | bloom syndrome protein | 0.0064 | 0.0566 | 0.0565 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0029 | 0.0213 | 0.0458 |
Entamoeba histolytica | recQ family helicase, putative | 0.0043 | 0.0357 | 0.7697 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0061 | 0.0061 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0109 | 0.1039 | 0.4017 |
Brugia malayi | purine nucleoside phosphorylase I, inosine and guanosine-specific family protein | 0.0259 | 0.2584 | 0.5558 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0043 | 0.0357 | 0.2376 |
Mycobacterium tuberculosis | Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) | 0.0009 | 0.0001 | 0.0004 |
Loa Loa (eye worm) | histone methyltransferase | 0.0011 | 0.0026 | 0.0026 |
Schistosoma mansoni | lamin | 0.0055 | 0.0476 | 0.1129 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0038 | 0.0298 | 0.0705 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.2583 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0033 | 0.0254 | 0.1188 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0417 | 0.0988 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0731 | 0.0731 |
Brugia malayi | Thioredoxin reductase | 0.0096 | 0.0903 | 0.1942 |
Brugia malayi | thymidylate synthase | 0.0109 | 0.1039 | 0.2234 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0038 | 0.0298 | 0.1152 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0038 | 0.0303 | 0.1417 |
Plasmodium vivax | glutathione reductase, putative | 0.0096 | 0.0903 | 0.6018 |
Loa Loa (eye worm) | glutathione reductase | 0.0096 | 0.0903 | 0.0903 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0298 | 0.0298 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0183 | 0.0183 |
Mycobacterium ulcerans | monoxygenase | 0.0009 | 0.0001 | 0.0004 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0058 | 0.0512 | 0.1214 |
Chlamydia trachomatis | endonuclease IV | 0.0078 | 0.0715 | 0.9776 |
Mycobacterium tuberculosis | Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase | 0.0054 | 0.0464 | 0.1794 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0219 | 0.2174 | 0.8416 |
Echinococcus multilocularis | tryptophan hydroxylase | 0.0978 | 1 | 1 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0054 | 0.0471 | 0.0471 |
Giardia lamblia | UPL-1 | 0.0054 | 0.0464 | 0.1794 |
Leishmania major | protein kinase, putative | 0.0013 | 0.0043 | 0.0195 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0033 | 0.0254 | 0.1188 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0011 | 0.0025 | 0.0054 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0055 | 0.0476 | 0.1024 |
Mycobacterium ulcerans | sugar phosphate isomerases/epimerases | 0.0021 | 0.0122 | 0.0471 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.0731 | 0.3432 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0043 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0173 | 0.0173 |
Schistosoma mansoni | DNA helicase recq1 | 0.0038 | 0.0303 | 0.0717 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0212 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | thymidylate synthase | 0.0109 | 0.1039 | 0.1039 |
Echinococcus granulosus | geminin | 0.0172 | 0.169 | 0.1689 |
Brugia malayi | hypothetical protein | 0.0241 | 0.2394 | 0.515 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0043 | 0.0357 | 0.1673 |
Onchocerca volvulus | 0.0009 | 0.0001 | 0.0002 | |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0107 | 0.2298 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0096 | 0.0903 | 0.0902 |
Giardia lamblia | Glutamate synthase | 0.0009 | 0.0001 | 0.0004 |
Brugia malayi | hypoxia-induced factor 1 | 0.0153 | 0.1492 | 0.3209 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0038 | 0.0298 | 0.0297 |
Onchocerca volvulus | 0.0029 | 0.0212 | 0.0433 | |
Onchocerca volvulus | 0.0055 | 0.0476 | 0.0973 | |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0107 | 0.0106 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0033 | 0.0254 | 0.0982 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0121 | 0.1162 | 0.1162 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0033 | 0.0254 | 0.0982 |
Loa Loa (eye worm) | RecQ helicase | 0.0064 | 0.0566 | 0.0566 |
Brugia malayi | Protein kinase domain containing protein | 0.0015 | 0.0061 | 0.0131 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0043 | 0.0087 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0058 | 0.0514 | 0.0512 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0045 | 0.037 | 0.1433 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.008 | 0.0731 | 0.1736 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0212 | 0.05 |
Mycobacterium ulcerans | thioredoxin reductase TrxB2 | 0.0009 | 0.0001 | 0.0004 |
Echinococcus granulosus | death domain containing protein | 0.0015 | 0.0061 | 0.006 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0033 | 0.0254 | 0.1687 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0033 | 0.0254 | 0.346 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.2583 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0029 | 0.0213 | 0.0213 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0033 | 0.0254 | 0.0601 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0061 | 0.0142 |
Mycobacterium ulcerans | endonuclease IV | 0.0078 | 0.0715 | 0.2768 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0107 | 0.1455 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0058 | 0.0512 | 0.2399 |
Brugia malayi | bHLH-PAS transcription factor | 0.0037 | 0.0288 | 0.062 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0061 | 0.0543 | 0.2548 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0254 | 0.1687 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.2583 |
Leishmania major | protein kinase, putative | 0.0013 | 0.0043 | 0.0195 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0038 | 0.0303 | 0.1417 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0033 | 0.0254 | 0.0519 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0009 | 0.0001 | 0.0004 |
Mycobacterium tuberculosis | NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) | 0.0009 | 0.0001 | 0.0004 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0229 | 0.0228 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0013 | 0.0043 | 0.0043 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0054 | 0.0464 | 0.1794 |
Echinococcus granulosus | Ankyrin | 0.0015 | 0.0062 | 0.0061 |
Brugia malayi | follicle stimulating hormone receptor | 0.0459 | 0.4649 | 1 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0009 | 0.0001 | 0.0002 |
Onchocerca volvulus | 0.0483 | 0.4891 | 1 | |
Chlamydia trachomatis | AMP nucleosidase | 0.0054 | 0.0464 | 0.6332 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0173 | 0.0173 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.008 | 0.0731 | 0.4875 |
Mycobacterium tuberculosis | Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) | 0.0078 | 0.0715 | 0.2768 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0039 | 0.0311 | 0.1457 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0033 | 0.0254 | 0.1687 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0043 | 0.0087 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0044 | 0.0365 | 0.0866 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0015 | 0.0061 | 0.006 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0096 | 0.0903 | 0.3493 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0033 | 0.0254 | 0.346 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.203 | 0.203 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0009 | 0.0001 | 0.0002 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 0.0948 |
Onchocerca volvulus | 0.0049 | 0.0417 | 0.0852 | |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0052 | 0.0448 | 0.0447 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0038 | 0.0298 | 0.0297 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0154 | 0.1499 | 1 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0043 | 0.0357 | 0.073 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0026 | 0.0183 | 0.0182 |
Onchocerca volvulus | 0.0055 | 0.0476 | 0.0973 | |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0058 | 0.0512 | 0.198 |
Brugia malayi | glutamate synthase | 0.0009 | 0.0001 | 0.0002 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0033 | 0.0254 | 0.1687 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0229 | 0.0541 |
Toxoplasma gondii | hypothetical protein | 0.0027 | 0.0193 | 0.0901 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0107 | 0.0416 |
Treponema pallidum | pfs protein (pfs) | 0.0054 | 0.0464 | 0.6332 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0038 | 0.0298 | 0.0609 |
Plasmodium falciparum | apurinic/apyrimidinic endonuclease Apn1, putative | 0.0078 | 0.0715 | 0.4766 |
Plasmodium vivax | apurinic/apyrimidinic endonuclease Apn1, putative | 0.0078 | 0.0715 | 0.4766 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0045 | 0.037 | 0.1429 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0731 | 0.2831 |
Echinococcus multilocularis | geminin | 0.0172 | 0.169 | 0.1689 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0058 | 0.0512 | 0.051 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0045 | 0.037 | 0.037 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0543 | 0.1289 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0043 | 0.0357 | 0.2376 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.2583 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0033 | 0.0254 | 0.1687 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 1 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0027 | 0.0193 | 0.0742 |
Brugia malayi | Uncoordinated protein 44 | 0.0015 | 0.0061 | 0.0131 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0013 | 0.0043 | 0.0277 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0026 | 0.0025 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.0193 | 0.128 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0054 | 0.0464 | 0.0948 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 0.3087 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0038 | 0.0303 | 0.0302 |
Brugia malayi | MTAP | 0.0054 | 0.0464 | 0.0997 |
Leishmania major | methylthioadenosine phosphorylase, putative | 0.0054 | 0.0464 | 0.2173 |
Echinococcus granulosus | intermediate filament protein | 0.0055 | 0.0476 | 0.0475 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0254 | 0.1188 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0008 | 0.0007 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0033 | 0.0254 | 0.0982 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0058 | 0.0512 | 0.1101 |
Toxoplasma gondii | phenylalanine-4-hydroxylase | 0.0215 | 0.2129 | 1 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0015 | 0.0062 | 0.0145 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0033 | 0.0254 | 0.1687 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0009 | 0.0001 | 0.0002 |
Leishmania major | phenylalanine-4-hydroxylase,phenylalanine-4-hydroxylase, putative | 0.0215 | 0.2129 | 1 |
Echinococcus granulosus | dihydrofolate reductase | 0.0045 | 0.037 | 0.0369 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0024 | 0.0163 | 0.035 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0038 | 0.0298 | 0.198 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0244 | 0.2427 | 0.9394 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0038 | 0.0298 | 0.6414 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0009 | 0.0001 | 0.0002 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0107 | 0.0416 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0038 | 0.0303 | 0.2013 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0013 | 0.0043 | 0.0087 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0043 | 0.0087 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0205 | 0.203 | 0.2029 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0015 | 0.0061 | 0.0131 |
Giardia lamblia | Purine nucleoside phosphorylase lateral transfer candidate | 0.0259 | 0.2584 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0061 | 0.0543 | 0.1168 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0715 | 0.0715 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0731 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0107 | 0.022 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0447 | 0.0961 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0015 | 0.0061 | 0.0142 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0061 | 0.0543 | 0.0542 |
Schistosoma mansoni | uridine phosphorylase | 0.0054 | 0.0464 | 0.1099 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0107 | 0.0416 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.2583 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0033 | 0.0254 | 0.1687 |
Echinococcus multilocularis | lamin dm0 | 0.0055 | 0.0476 | 0.0475 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0013 | 0.0043 | 0.0277 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0058 | 0.0511 | 0.3406 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 0.0948 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0015 | 0.0061 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0466 | 0.0466 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0154 | 0.1499 | 1 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0013 | 0.0043 | 0.0087 |
Trypanosoma cruzi | methylthioadenosine phosphorylase, putative | 0.0054 | 0.0464 | 0.3087 |
Schistosoma mansoni | tyrosine 3-monooxygenase | 0.0215 | 0.2129 | 0.5059 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.2583 |
Brugia malayi | MH2 domain containing protein | 0.0121 | 0.1162 | 0.25 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0024 | 0.0163 | 0.035 |
Mycobacterium tuberculosis | Probable reductase | 0.0219 | 0.2174 | 0.8416 |
Schistosoma mansoni | intermediate filament proteins | 0.0055 | 0.0476 | 0.1129 |
Brugia malayi | uridine phosphorylase family protein | 0.0054 | 0.0464 | 0.0997 |
Plasmodium vivax | purine nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 0.3087 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0009 | 0.0001 | 0.0001 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0009 | 0.0001 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0373 | 0.0373 |
Toxoplasma gondii | Purine nucleoside phosphorylase | 0.0054 | 0.0464 | 0.2173 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0058 | 0.0505 | 0.2366 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0009 | 0.0001 | 0.0002 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0009 | 0.0001 | 0.0002 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0096 | 0.0903 | 0.0903 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0543 | 0.1289 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0075 | 0.0683 | 0.0682 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0015 | 0.0061 | 0.006 |
Mycobacterium tuberculosis | Possible dehydrogenase/reductase | 0.0009 | 0.0001 | 0.0004 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0033 | 0.0254 | 0.0546 |
Giardia lamblia | Glycerol-3-phosphate dehydrogenase | 0.0009 | 0.0001 | 0.0004 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0055 | 0.0476 | 0.0476 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0731 | 1 |
Mycobacterium leprae | probable uridine phosphorylase | 0.0054 | 0.0464 | 0.179 |
Treponema pallidum | ATP-dependent DNA helicase | 0.0019 | 0.011 | 0.1491 |
Loa Loa (eye worm) | S-methyl-5'-thioadenosine phosphorylase MTAP | 0.0054 | 0.0464 | 0.0464 |
Schistosoma mansoni | lamin | 0.0055 | 0.0476 | 0.1129 |
Echinococcus multilocularis | uridine phosphorylase 1 | 0.0054 | 0.0464 | 0.0462 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 0.3087 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0038 | 0.0303 | 0.0651 |
Toxoplasma gondii | aromatic amino acid hydrolase AAH1 | 0.0215 | 0.2129 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0122 | 0.0122 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0038 | 0.0298 | 0.1394 |
Mycobacterium ulcerans | putative regulatory protein | 0.0037 | 0.0288 | 0.1115 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0096 | 0.0903 | 0.6018 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0417 | 0.0896 |
Treponema pallidum | uridine phosphorylase (udp) | 0.0054 | 0.0464 | 0.6332 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0054 | 0.0464 | 0.0948 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0033 | 0.0254 | 0.1188 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0038 | 0.0303 | 0.0302 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0731 | 0.4875 |
Trypanosoma brucei | trypanothione reductase | 0.0096 | 0.0903 | 0.6018 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0038 | 0.0298 | 0.0297 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.2583 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0013 | 0.0043 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0543 | 0.0543 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0244 | 0.2427 | 0.9394 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0219 | 0.2174 | 0.8416 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0009 | 0.0001 | 0.0002 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0052 | 0.0448 | 0.1735 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0064 | 0.0573 | 0.1359 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0043 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0978 | 1 | 1 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0013 | 0.0043 | 0.0277 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0154 | 0.1499 | 0.704 |
Toxoplasma gondii | endonuclease IV APN | 0.0078 | 0.0715 | 0.3356 |
Giardia lamblia | 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase | 0.0054 | 0.0464 | 0.1794 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0015 | 0.0061 | 0.006 |
Echinococcus multilocularis | lamin | 0.0055 | 0.0476 | 0.0475 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0154 | 0.1499 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0107 | 0.1455 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.169 | 0.4016 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0107 | 0.022 |
Mycobacterium ulcerans | 5'-methylthioadenosine phosphorylase | 0.0054 | 0.0464 | 0.1794 |
Brugia malayi | glutathione reductase | 0.0096 | 0.0903 | 0.1942 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.0731 | 0.3432 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0052 | 0.0448 | 0.0447 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0033 | 0.0254 | 0.1188 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0107 | 0.0231 |
Mycobacterium ulcerans | NADPH dependent 2,4-dienoyl-CoA reductase FadH | 0.0009 | 0.0001 | 0.0004 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0009 | 0.0001 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0476 | 0.0476 |
Mycobacterium tuberculosis | Probable thioredoxin reductase TrxB2 (TRXR) (TR) | 0.0009 | 0.0001 | 0.0004 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0107 | 0.0709 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0008 | 0.0007 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0009 | 0.0008 | 0.0007 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0061 | 0.0543 | 0.0542 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 0.0948 |
Plasmodium falciparum | glutathione reductase | 0.0096 | 0.0903 | 0.6018 |
Mycobacterium tuberculosis | Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) | 0.0009 | 0.0001 | 0.0004 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.0731 | 1 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0107 | 0.0106 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0205 | 0.203 | 0.2029 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0096 | 0.0903 | 0.0902 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0107 | 0.0709 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 0.3087 |
Plasmodium falciparum | purine nucleoside phosphorylase | 0.0054 | 0.0464 | 0.3087 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0009 | 0.0008 | 0.0007 |
Mycobacterium tuberculosis | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0009 | 0.0001 | 0.0004 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0298 | 0.0609 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 1 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0009 | 0.0001 | 0.0002 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh | 0.0009 | 0.0001 | 0.0004 |
Trypanosoma cruzi | methylthioadenosine phosphorylase, putative | 0.0054 | 0.0464 | 0.3087 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0229 | 0.0541 |
Treponema pallidum | NADH oxidase | 0.0033 | 0.0254 | 0.346 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0033 | 0.0254 | 0.1687 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0219 | 0.2174 | 0.8415 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0096 | 0.0903 | 0.6018 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0038 | 0.0298 | 0.0297 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.011 | 0.0512 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0013 | 0.0043 | 0.0195 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0064 | 0.0566 | 0.1157 |
Plasmodium falciparum | glutathione reductase | 0.0033 | 0.0254 | 0.1687 |
Onchocerca volvulus | Purine nucleoside phosphorylase homolog | 0.0259 | 0.2584 | 0.5283 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0045 | 0.037 | 0.1433 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0038 | 0.0298 | 0.0705 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0033 | 0.0254 | 0.1687 |
Mycobacterium ulcerans | bifunctional Mta/Sah nucleosidase Mtn | 0.0054 | 0.0464 | 0.1794 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.011 | 0.0259 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0009 | 0.0001 | 0.0004 |
Echinococcus granulosus | inosine guanosine and xanthosine phosphorylase | 0.0205 | 0.203 | 0.2029 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0054 | 0.0464 | 0.1794 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0075 | 0.0683 | 0.0682 |
Mycobacterium ulcerans | thymidylate synthase | 0.0109 | 0.1039 | 0.402 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0064 | 0.0566 | 0.1157 |
Brugia malayi | Probable ClpP-like protease | 0.008 | 0.0731 | 0.1573 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0212 | 0.0455 |
Trichomonas vaginalis | dihydrolipoamide dehydrogenase, putative | 0.0009 | 0.0001 | 0.0002 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0043 | 0.0087 |
Entamoeba histolytica | hypothetical protein | 0.0054 | 0.0464 | 1 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0052 | 0.0448 | 0.1735 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0038 | 0.0298 | 0.064 |
Mycobacterium tuberculosis | Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) | 0.0259 | 0.2584 | 1 |
Plasmodium vivax | ATP-dependent DNA helicase Q1, putative | 0.0019 | 0.0102 | 0.0676 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 1 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 0.0948 |
Toxoplasma gondii | thioredoxin reductase | 0.0096 | 0.0903 | 0.4237 |
Mycobacterium ulcerans | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 1 |
Echinococcus multilocularis | Ankyrin | 0.0015 | 0.0062 | 0.0061 |
Echinococcus multilocularis | methylthioadenosine phosphorylase | 0.0054 | 0.0464 | 0.0462 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0254 | 0.1687 |
Brugia malayi | Biopterin-dependent aromatic amino acid hydroxylase family protein | 0.0215 | 0.2129 | 0.4579 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0021 | 0.0122 | 0.0471 |
Loa Loa (eye worm) | tryptophan hydroxylase 1 | 0.0215 | 0.2129 | 0.2129 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0009 | 0.0001 | 0.0002 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0037 | 0.0288 | 0.0287 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.2583 |
Mycobacterium leprae | conserved hypothetical protein | 0.0021 | 0.0122 | 0.0466 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0038 | 0.0298 | 0.198 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0061 | 0.0543 | 0.1289 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0254 | 0.1687 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0054 | 0.0464 | 0.0948 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0026 | 0.0183 | 0.0182 |
Plasmodium vivax | SET domain protein, putative | 0.0061 | 0.0543 | 0.3619 |
Schistosoma mansoni | uridine phosphorylase | 0.0054 | 0.0464 | 0.1099 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0259 | 0.2584 | 0.2583 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.0054 | 0.0464 | 0.1099 |
Mycobacterium ulcerans | hypothetical protein | 0.0021 | 0.0122 | 0.0471 |
Mycobacterium ulcerans | glutamate synthase subunit beta | 0.0009 | 0.0001 | 0.0004 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0219 | 0.2174 | 0.8416 |
Brugia malayi | Dihydrofolate reductase | 0.0045 | 0.037 | 0.0796 |
Loa Loa (eye worm) | intermediate filament protein | 0.0055 | 0.0476 | 0.0476 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | ug ml-1 | Compound was evaluated for antibacterial activity against Escherichia coli ATCC25922; Inactive | ChEMBL. | No reference |
MIC (functional) | 0 ug ml-1 | Compound was evaluated for antibacterial activity against Escherichia coli ATCC25922; Inactive | ChEMBL. | No reference |
MIC (functional) | 0 ug ml-1 | Compound was evaluated for antibacterial activity against Staphylococcus aureus ATCC29213; Inactive | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.