Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | quinone oxidoreductase, putative | 0.0027 | 0.0013 | 0.0033 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0106 | 0.0691 | 0.2331 |
Plasmodium falciparum | carbonic anhydrase | 0.0027 | 0.0012 | 0.0601 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0049 | 0.02 | 1 |
Trypanosoma cruzi | nuclear receptor binding factor, putative | 0.0027 | 0.0013 | 0.0166 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0078 | 0.0153 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.0055 | 0.0101 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0027 | 0.0012 | 0.0041 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0119 | 0.0801 | 0.2704 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1822 | 0.6152 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0174 | 0.0589 |
Trichomonas vaginalis | set domain proteins, putative | 0.0255 | 0.1972 | 0.1961 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.0055 | 0.0326 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0013 | 0.0045 |
Schistosoma mansoni | hypothetical protein | 0.0311 | 0.2446 | 0.5681 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0049 | 0.02 | 0.2501 |
Onchocerca volvulus | Putative alcohol dehydrogenase | 0.0224 | 0.17 | 0.8612 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0049 | 0.02 | 0.0676 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0027 | 0.0012 | 0.0041 |
Echinococcus multilocularis | X box binding protein 1 | 0.0311 | 0.2446 | 0.3346 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0156 | 0.0336 |
Schistosoma mansoni | patched 1 | 0.0046 | 0.017 | 0.0369 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0049 | 0.02 | 0.0439 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0119 | 0.0801 | 0.2704 |
Echinococcus multilocularis | protein dispatched 1 | 0.0052 | 0.0225 | 0.0293 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.0738 | 0.1812 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0112 | 0.0738 | 0.1695 |
Echinococcus granulosus | geminin | 0.0526 | 0.4297 | 1 |
Trypanosoma cruzi | oxidoreductase, putative | 0.0027 | 0.0013 | 0.0166 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0156 | 0.0336 |
Leishmania major | NADP-dependent alcohol dehydrogenase, putative | 0.0027 | 0.0013 | 0.0033 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0119 | 0.0801 | 0.2704 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.0326 | 0.1102 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0691 | 0.2331 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0055 | 0.0187 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0055 | 0.2768 |
Mycobacterium ulcerans | proteasome PrcA | 0.088 | 0.7336 | 0.7332 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0874 | 0.7286 | 1 |
Mycobacterium tuberculosis | Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. | 0.088 | 0.7336 | 0.9244 |
Schistosoma mansoni | hypothetical protein | 0.0526 | 0.4297 | 1 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0027 | 0.0013 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0012 | 0.0041 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.0326 | 0.0432 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0112 | 0.0738 | 0.1695 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0049 | 0.02 | 0.1178 |
Onchocerca volvulus | 0.0049 | 0.0196 | 0.0932 | |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0371 | 0.2962 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0174 | 0.0379 |
Echinococcus granulosus | mitochondrial trans 2 enoyl coenzyme A reductase | 0.0027 | 0.0013 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0196 | 0.0429 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0027 | 0.0012 | 0.0041 |
Onchocerca volvulus | 0.0032 | 0.0055 | 0.0215 | |
Trypanosoma cruzi | oxidoreductase, putative | 0.0027 | 0.0013 | 0.0166 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0027 | 0.0013 | 0.0166 |
Mycobacterium tuberculosis | Possible zinc-containing alcohol dehydrogenase NAD dependent AdhB | 0.0196 | 0.1466 | 0.1834 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.017 | 0.0575 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.0738 | 0.1812 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.0326 | 0.0734 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.0055 | 0.0101 |
Mycobacterium ulcerans | zinc-containing alcohol dehydrogenase NAD dependent AdhB | 0.0224 | 0.17 | 0.1689 |
Trypanosoma cruzi | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.0032 | 0.0052 | 0.0647 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0156 | 0.0336 |
Mycobacterium ulcerans | transmembrane carbonic anhydrase, SulP | 0.0032 | 0.0052 | 0.0039 |
Schistosoma mansoni | zinc binding dehydrogenase | 0.0027 | 0.0013 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0013 | 0.0045 |
Schistosoma mansoni | carbonic anhydrase | 0.0493 | 0.4014 | 0.9341 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.0055 | 0.006 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0119 | 0.0801 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0013 | 0.0045 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0055 | 0.006 |
Mycobacterium ulcerans | zinc-containing alcohol dehydrogenase NAD-dependent AdhB | 0.0224 | 0.17 | 0.1689 |
Brugia malayi | hypothetical protein | 0.0238 | 0.1822 | 0.6152 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0238 | 0.1822 | 0.4225 |
Onchocerca volvulus | Huntingtin homolog | 0.0132 | 0.0913 | 0.4595 |
Brugia malayi | Isocitrate dehydrogenase | 0.0049 | 0.02 | 0.0676 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0012 | 0.0041 |
Brugia malayi | hypothetical protein | 0.0112 | 0.0738 | 0.2493 |
Brugia malayi | MH2 domain containing protein | 0.0371 | 0.2962 | 1 |
Onchocerca volvulus | 0.0199 | 0.1491 | 0.7546 | |
Schistosoma mansoni | hypothetical protein | 0.0112 | 0.0738 | 0.1695 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0112 | 0.0738 | 0.0998 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0106 | 0.0691 | 0.1693 |
Leishmania major | oxidoreductase-like protein | 0.0027 | 0.0013 | 0.0033 |
Schistosoma mansoni | hypothetical protein | 0.0526 | 0.4297 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0238 | 0.1822 | 0.2489 |
Echinococcus granulosus | expressed conserved protein | 0.01 | 0.0635 | 0.1454 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.095 | 0.7934 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0156 | 0.0336 |
Echinococcus multilocularis | expressed conserved protein | 0.01 | 0.0635 | 0.0857 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0119 | 0.0801 | 0.1841 |
Brugia malayi | Pre-SET motif family protein | 0.0224 | 0.1706 | 0.5759 |
Leishmania major | carbonic anhydrase-like protein | 0.0119 | 0.0801 | 0.1995 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0049 | 0.02 | 0.0499 |
Mycobacterium ulcerans | carbonic anhydrase | 0.0493 | 0.4014 | 0.4006 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0174 | 0.0379 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.0493 | 0.4014 | 0.5464 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0049 | 0.02 | 0.0259 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0049 | 0.02 | 0.0439 |
Leishmania major | carbonic anhydrase family protein, putative | 0.0493 | 0.4014 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0224 | 0.1706 | 0.5759 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.0913 | 0.3083 |
Brugia malayi | hypothetical protein | 0.0132 | 0.0913 | 0.3083 |
Mycobacterium ulcerans | integral membrane transporter | 0.0032 | 0.0052 | 0.0039 |
Mycobacterium leprae | probable proteasome (alpha subunit) PrcA | 0.088 | 0.7336 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0152 | 0.1082 | 0.2496 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0196 | 0.0429 |
Schistosoma mansoni | alcohol dehydrogenase | 0.0224 | 0.17 | 0.3939 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.0326 | 0.1102 |
Plasmodium falciparum | inorganic anion exchanger, inorganic anion antiporter | 0.0032 | 0.0052 | 0.2588 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0216 | 0.0729 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0049 | 0.02 | 0.0259 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0326 | 0.0734 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0049 | 0.02 | 0.1178 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.0326 | 0.1102 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0326 | 0.0734 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0174 | 0.0223 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0216 | 0.0729 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0078 | 0.0262 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.0738 | 0.1812 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0049 | 0.02 | 1 |
Leishmania major | oxidoreductase, putative | 0.0027 | 0.0013 | 0.0033 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0106 | 0.0691 | 0.0933 |
Trichomonas vaginalis | conserved hypothetical protein | 0.119 | 1 | 1 |
Mycobacterium tuberculosis | Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) | 0.0224 | 0.17 | 0.2129 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0046 | 0.017 | 0.0575 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0174 | 0.0379 |
Mycobacterium leprae | Probable S-nitrosomycothiol reductase MscR | 0.0224 | 0.17 | 0.2303 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0119 | 0.0801 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0371 | 0.2962 | 1 |
Plasmodium vivax | sulfate transporter, putative | 0.0032 | 0.0052 | 0.2588 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0119 | 0.0801 | 1 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.0471 | 0.3823 | 0.4809 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0045 | 0.0078 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0027 | 0.0012 | 0.0041 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0326 | 0.0734 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.0326 | 0.1102 |
Onchocerca volvulus | Putative sulfate transporter | 0.0199 | 0.1491 | 0.7546 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0046 | 0.017 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.0913 | 0.3083 |
Brugia malayi | isocitrate dehydrogenase | 0.0049 | 0.02 | 0.0676 |
Trypanosoma brucei | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.0032 | 0.0052 | 0.0647 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0174 | 0.0379 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0046 | 0.017 | 0.0369 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0326 | 0.0734 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0049 | 0.02 | 0.0259 |
Mycobacterium leprae | Probable transmembrane transport protein | 0.023 | 0.1757 | 0.2381 |
Wolbachia endosymbiont of Brugia malayi | NADPH:quinone reductase | 0.0027 | 0.0013 | 0.5 |
Echinococcus multilocularis | geminin | 0.0526 | 0.4297 | 0.5891 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0049 | 0.02 | 0.2501 |
Toxoplasma gondii | inorganic anion transporter, sulfate permease (SulP) family protein | 0.0032 | 0.0052 | 0.0305 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0049 | 0.02 | 0.0259 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0055 | 0.0101 |
Onchocerca volvulus | Huntingtin homolog | 0.0132 | 0.0913 | 0.4595 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0027 | 0.0013 | 0.0166 |
Trypanosoma brucei | oxidoreductase, putative | 0.0027 | 0.0013 | 0.0166 |
Toxoplasma gondii | quinone oxidoreductase, putative | 0.0027 | 0.0013 | 0.0078 |
Brugia malayi | Alcohol dehydrogenase class III | 0.0224 | 0.17 | 0.5739 |
Trypanosoma brucei | oxidoreductase, putative | 0.0027 | 0.0013 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0012 | 0.0041 |
Chlamydia trachomatis | sulfate transporter | 0.0032 | 0.0052 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0078 | 0.0262 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0049 | 0.02 | 0.2501 |
Trypanosoma cruzi | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.0032 | 0.0052 | 0.0647 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0174 | 0.0379 |
Echinococcus granulosus | X box binding protein 1 | 0.0311 | 0.2446 | 0.5681 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0055 | 0.0187 |
Mycobacterium tuberculosis | Probable zinc-type alcohol dehydrogenase (E subunit) AdhE1 | 0.0196 | 0.1466 | 0.1834 |
Mycobacterium tuberculosis | Probable conserved transmembrane protein | 0.023 | 0.1757 | 0.2201 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0046 | 0.017 | 0.0217 |
Brugia malayi | CHE-14 protein | 0.0046 | 0.017 | 0.0575 |
Toxoplasma gondii | Zn-containing alcohol dehydrogenase | 0.0224 | 0.17 | 1 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0027 | 0.0012 | 0.0041 |
Entamoeba histolytica | carbonic anhydrase, putative | 0.0493 | 0.4014 | 1 |
Trypanosoma cruzi | nuclear receptor binding factor, putative | 0.0027 | 0.0013 | 0.0166 |
Toxoplasma gondii | hypothetical protein | 0.0027 | 0.0012 | 0.0071 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0027 | 0.0012 | 0.0041 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0174 | 0.0589 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0326 | 0.0734 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0046 | 0.017 | 0.0157 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0049 | 0.02 | 0.2501 |
Mycobacterium ulcerans | transmembrane carbonic anhydrase, SulP | 0.0032 | 0.0052 | 0.0039 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0119 | 0.0801 | 0.1841 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0174 | 0.0223 |
Echinococcus granulosus | carbonic anhydrase II | 0.0119 | 0.0801 | 0.1841 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0152 | 0.1082 | 0.147 |
Loa Loa (eye worm) | alcohol dehydrogenase class III | 0.0224 | 0.17 | 0.5739 |
Brugia malayi | RNA binding protein | 0.0064 | 0.0326 | 0.1102 |
Onchocerca volvulus | 0.0255 | 0.1972 | 1 | |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0027 | 0.0013 | 0.0045 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0049 | 0.02 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0258 | 0.0872 |
Mycobacterium ulcerans | zinc-dependent alcohol dehydrogenase AdhE2 | 0.0224 | 0.17 | 0.1689 |
Mycobacterium ulcerans | zinc-dependent alcohol dehydrogenase | 0.0224 | 0.17 | 0.1689 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0216 | 0.0729 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0055 | 0.0101 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0108 | 0.0705 | 0.1616 |
Entamoeba histolytica | hypothetical protein | 0.0112 | 0.0738 | 0.1812 |
Echinococcus multilocularis | protein patched | 0.0046 | 0.017 | 0.0217 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.0253 | 0.1948 | 0.2443 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0055 | 0.0101 |
Echinococcus multilocularis | mitochondrial trans 2 enoyl coenzyme A reductase | 0.0027 | 0.0013 | 0.0002 |
Leishmania major | d-xylulose reductase, putative | 0.0027 | 0.0013 | 0.0033 |
Trichomonas vaginalis | conserved hypothetical protein | 0.119 | 1 | 1 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0027 | 0.0013 | 0.0166 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.0326 | 0.1102 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0049 | 0.02 | 0.0236 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0216 | 0.0729 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0027 | 0.0013 | 0.0166 |
Mycobacterium ulcerans | zinc-type alcohol dehydrogenase AdhD | 0.0224 | 0.17 | 0.1689 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0119 | 0.0801 | 0.2704 |
Leishmania major | zinc binding dehydrogenase-like protein | 0.0027 | 0.0013 | 0.0033 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0106 | 0.0691 | 0.1583 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0119 | 0.0801 | 0.1084 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0196 | 0.0661 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0027 | 0.0013 | 0.0078 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Log PR (ADMET) | -1.2 | log PR value of the compound was determined (eq 2) | ChEMBL. | 2455052 |
Log PR (ADMET) | = -0.29 | log PR value | ChEMBL. | 2455052 |
pK3 | 8.26 | Dissociation constant of the compound (eq 2) | ChEMBL. | 2455052 |
Potency ratio (functional) | = 0.063 | In vitro inhibition of anti-IgE induced histamine release from bronchoalveolar mast cells of monkey infected with Ascaris suum | ChEMBL. | 2455052 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.