Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Receptor family ligand binding region containing protein | 0.0196 | 0.0754 | 0.0715 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0136 | 0.0421 | 0.0421 |
Onchocerca volvulus | Atrial natriuretic peptide receptor 3 homolog | 0.0074 | 0.0073 | 0.0012 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0136 | 0.0421 | 0.0421 |
Echinococcus multilocularis | protein kinase shaggy | 0.1849 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.01 | 0.022 | 0.016 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0136 | 0.0421 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.0754 | 0.0754 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.1849 | 1 | 1 |
Echinococcus multilocularis | glycogen synthase kinase 3 beta | 0.1849 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0076 | 0.0084 | 0.0084 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0868 | 0.4513 | 0.4479 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0136 | 0.0421 | 0.038 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0136 | 0.0421 | 0.0361 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0639 | 0.3236 | 0.3194 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0136 | 0.0421 | 0.0361 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.01 | 0.022 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.0421 | 0.0421 |
Schistosoma mansoni | tyrosine kinase | 0.0076 | 0.0084 | 0.0022 |
Leishmania major | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 0.1849 | 1 | 1 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.1849 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1849 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.022 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.022 | 0.022 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0136 | 0.0421 | 0.0421 |
Loa Loa (eye worm) | TK protein kinase | 0.0068 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0074 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0062 | 0.0062 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.094 | 0.4915 | 0.4915 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.0196 | 0.0754 | 0.0754 |
Loa Loa (eye worm) | glutamate receptor | 0.0763 | 0.3929 | 0.3929 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0136 | 0.0421 | 0.0361 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0136 | 0.0421 | 0.0421 |
Onchocerca volvulus | 0.1849 | 1 | 1 | |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0124 | 0.0353 | 0.0312 |
Echinococcus granulosus | atrial natriuretic peptide receptor | 0.0072 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.0421 | 0.0421 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0136 | 0.0421 | 0.0421 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0072 | 0.0062 | 0.0062 |
Brugia malayi | steroid hormone receptor | 0.0136 | 0.0421 | 0.038 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0136 | 0.0421 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0062 | 0.0062 |
Schistosoma mansoni | tyrosine kinase | 0.0074 | 0.0073 | 0.0012 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0136 | 0.0421 | 0.0421 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0136 | 0.0421 | 0.0361 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.01 | 0.022 | 0.016 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0076 | 0.0084 | 0.0084 |
Echinococcus multilocularis | receptor type guanylyl cyclase | 0.0074 | 0.0073 | 0.0073 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0136 | 0.0421 | 0.0421 |
Schistosoma mansoni | coup transcription factor | 0.0136 | 0.0421 | 0.0361 |
Brugia malayi | Guanylyl cyclase protein 23 | 0.0074 | 0.0073 | 0.0031 |
Onchocerca volvulus | 0.0074 | 0.0073 | 0.0012 | |
Echinococcus granulosus | protein kinase shaggy | 0.1849 | 1 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase GSK, putative | 0.1849 | 1 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.1849 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1849 | 1 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.1849 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0072 | 0.0062 | 0.0062 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0068 | 0.0042 | 0.0042 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0136 | 0.0421 | 0.038 |
Onchocerca volvulus | Poor gastrulation protein homolog | 0.0124 | 0.0353 | 0.0293 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0136 | 0.0421 | 0.0361 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0072 | 0.0062 | 0.0062 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0076 | 0.0084 | 0.0084 |
Brugia malayi | hypothetical protein | 0.01 | 0.022 | 0.0179 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0136 | 0.0421 | 0.038 |
Schistosoma mansoni | glycogen synthase kinase 3-related (gsk3) (cmgc group III) | 0.1849 | 1 | 1 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0068 | 0.0042 | 0.0042 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0136 | 0.0421 | 0.0421 |
Schistosoma mansoni | nuclear hormone receptor | 0.0136 | 0.0421 | 0.0361 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0136 | 0.0421 | 0.0361 |
Entamoeba histolytica | protein kinase, putative | 0.1849 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.0421 | 0.0421 |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0072 | 0.0062 | 0.0019 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0076 | 0.0084 | 0.0084 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0136 | 0.0421 | 0.0361 |
Echinococcus granulosus | receptor type guanylyl cyclase | 0.0074 | 0.0073 | 0.0073 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0136 | 0.0421 | 0.0361 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0072 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.01 | 0.022 | 0.022 |
Echinococcus granulosus | glycogen synthase kinase 3 beta | 0.1849 | 1 | 1 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.0196 | 0.0754 | 0.0754 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.01 | 0.022 | 0.0179 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0066 | 0.003 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.1287 | 0.6856 | 0.6856 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0076 | 0.0084 | 0.0084 |
Schistosoma mansoni | tyrosine kinase | 0.0076 | 0.0084 | 0.0022 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0136 | 0.0421 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.0353 | 0.0353 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0072 | 0.0062 | 0.0062 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0136 | 0.0421 | 0.0361 |
Brugia malayi | nuclear hormone receptor | 0.0136 | 0.0421 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0073 | 0.0073 |
Schistosoma mansoni | tyrosine kinase | 0.0074 | 0.0073 | 0.0012 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0136 | 0.0421 | 0.0421 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0066 | 0.003 | 0.003 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0763 | 0.3929 | 0.3903 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0076 | 0.0084 | 0.0084 |
Onchocerca volvulus | Bile acid receptor homolog | 0.1287 | 0.6856 | 0.6837 |
Echinococcus granulosus | tyrosine kinase | 0.0074 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | metabotropic glutamate receptor 8 | 0.0072 | 0.0062 | 0.0062 |
Echinococcus granulosus | glutamate receptor 2 | 0.0072 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0062 | 0.0062 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0136 | 0.0421 | 0.0421 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0072 | 0.0062 | 0.0062 |
Plasmodium vivax | glycogen synthase kinase 3, putative | 0.1849 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.0421 | 0.0421 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0136 | 0.0421 | 0.0421 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0136 | 0.0421 | 0.0421 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.01 | 0.022 | 0.022 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0136 | 0.0421 | 0.0421 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0136 | 0.0421 | 0.0361 |
Echinococcus multilocularis | atrial natriuretic peptide receptor | 0.0072 | 0.0062 | 0.0062 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0136 | 0.0421 | 0.038 |
Echinococcus granulosus | FTZ F1 alpha | 0.0136 | 0.0421 | 0.0421 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0136 | 0.0421 | 0.0421 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0136 | 0.0421 | 0.038 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0136 | 0.0421 | 0.0421 |
Schistosoma mansoni | thyroid hormone receptor | 0.0136 | 0.0421 | 0.0361 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0062 | 0.0062 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.094 | 0.4915 | 0.4915 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0136 | 0.0421 | 0.0361 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0076 | 0.0084 | 0.0084 |
Brugia malayi | hypothetical protein | 0.0072 | 0.0062 | 0.0019 |
Trypanosoma brucei | protein kinase, putative | 0.1849 | 1 | 0.5 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0074 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.022 | 0.022 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0076 | 0.0084 | 0.0084 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0136 | 0.0421 | 0.038 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0068 | 0.0042 | 0.0042 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.01 | 0.022 | 0.0179 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0076 | 0.0084 | 0.0084 |
Onchocerca volvulus | 0.0136 | 0.0421 | 0.0361 | |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0136 | 0.0421 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.0421 | 0.0421 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0372 | 0.1741 | 0.1689 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0136 | 0.0421 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.022 | 0.022 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0068 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.094 | 0.4915 | 0.4915 |
Schistosoma mansoni | protein kinase | 0.0074 | 0.0073 | 0.0012 |
Brugia malayi | hypothetical protein | 0.01 | 0.022 | 0.0179 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0076 | 0.0084 | 0.0084 |
Brugia malayi | ecdysteroid receptor | 0.1287 | 0.6856 | 0.6843 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0072 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.0421 | 0.0421 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0692 | 0.3527 | 0.35 |
Loa Loa (eye worm) | SRC-1 | 0.0076 | 0.0084 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0062 | 0.0062 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0639 | 0.3236 | 0.3236 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0076 | 0.0084 | 0.0084 |
Brugia malayi | nuclear receptor RXR | 0.01 | 0.022 | 0.0179 |
Echinococcus granulosus | GPCR family 3 C terminal | 0.0124 | 0.0353 | 0.0353 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0074 | 0.0073 | 0.0073 |
Giardia lamblia | Kinase, CMGC GSK | 0.1849 | 1 | 0.5 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0072 | 0.0062 | 0.0062 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0136 | 0.0421 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | glutamate receptor | 0.03 | 0.1339 | 0.1339 |
Brugia malayi | SRC-1 | 0.0076 | 0.0084 | 0.0041 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0068 | 0.0042 | 0.0042 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0072 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0062 | 0.0062 |
Echinococcus granulosus | tyrosine kinase | 0.0068 | 0.0042 | 0.0042 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0136 | 0.0421 | 0.038 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0136 | 0.0421 | 0.038 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0136 | 0.0421 | 0.0421 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0136 | 0.0421 | 0.0421 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0076 | 0.0084 | 0.0084 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0076 | 0.0084 | 0.0084 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0136 | 0.0421 | 0.038 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0072 | 0.0062 | 0.0062 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0639 | 0.3236 | 0.3236 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0076 | 0.0084 | 0.0084 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0136 | 0.0421 | 0.038 |
Onchocerca volvulus | Metabotropic glutamate receptor homolog | 0.0124 | 0.0353 | 0.0293 |
Schistosoma mansoni | thyroid hormone receptor | 0.0136 | 0.0421 | 0.0361 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0136 | 0.0421 | 0.038 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0072 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.022 | 0.022 |
Plasmodium falciparum | glycogen synthase kinase 3 | 0.1849 | 1 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0093 | 0.0183 | 0.0183 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0136 | 0.0421 | 0.0421 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0372 | 0.1741 | 0.1706 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0076 | 0.0084 | 0.0084 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0136 | 0.0421 | 0.0421 |
Giardia lamblia | Kinase, CMGC GSK | 0.1849 | 1 | 0.5 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0074 | 0.0073 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.0421 | 0.0421 |
Trypanosoma cruzi | glycogen synthase kinase 3, putative | 0.1849 | 1 | 1 |
Echinococcus granulosus | glutamate receptor 2 | 0.0072 | 0.0062 | 0.0062 |
Brugia malayi | nuclear receptor NHR-88 | 0.0136 | 0.0421 | 0.038 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0072 | 0.0062 | 0.0062 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0136 | 0.0421 | 0.038 |
Schistosoma mansoni | hypothetical protein | 0.0124 | 0.0353 | 0.0293 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0136 | 0.0421 | 0.038 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0136 | 0.0421 | 0.038 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0136 | 0.0421 | 0.038 |
Echinococcus multilocularis | GPCR, family 3, C terminal | 0.0124 | 0.0353 | 0.0353 |
Echinococcus multilocularis | tyrosine kinase | 0.0074 | 0.0073 | 0.0073 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0136 | 0.0421 | 0.038 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0076 | 0.0084 | 0.0084 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.1 ug ml-1 | Antiviral activity against herpes simplex virus type 1 (HSV-1) determined in baby hamster kidney cells | ChEMBL. | 6887201 |
MIC50 (functional) | = 7 ug ml-1 | Compound was tested for antitumor activity against HSV-1 TK gene transformed TK deficient FM3A cells | ChEMBL. | 3039140 |
MIC50 (functional) | = 20 ug ml-1 | Compound was tested for antiviral activity against herpes simplex virus( HSV-1-KOS) strain in primary rabbit kidney cells | ChEMBL. | 3039140 |
MIC50 (functional) | = 20 ug ml-1 | Compound was tested for antiviral activity against herpes simplex virus( HSV-1-McIntyre) strain in primary rabbit kidney cells | ChEMBL. | 3039140 |
MIC50 (functional) | = 70 ug ml-1 | Compound was tested for antiviral activity against herpes simplex virus( HSV-1-F) strain in primary rabbit kidney cells | ChEMBL. | 3039140 |
MIC50 (functional) | = 100 ug ml-1 | Compound was tested for antiviral activity against Vaccinia virus in primary rabbit kidney cells | ChEMBL. | 3039140 |
MIC50 (functional) | > 100 ug ml-1 | Compound was tested for antitumor activity against L1210 cells | ChEMBL. | 3039140 |
MIC50 (functional) | > 100 ug ml-1 | Compound was tested for antitumor activity against FM3A/0 mammary carcinoma cells | ChEMBL. | 3039140 |
MIC50 (functional) | > 100 ug ml-1 | Compound was tested for antitumor activity against FM3A/TK- cells | ChEMBL. | 3039140 |
MIC50 (functional) | > 100 ug ml-1 | Compound was tested for antitumor activity against human B-lymphoblast Raji/0 cells | ChEMBL. | 3039140 |
MIC50 (functional) | > 100 ug ml-1 | Compound was tested for antitumor activity against thymidine kinase deficient human B-lymphoblast Raji/0 cells | ChEMBL. | 3039140 |
MIC50 (functional) | > 100 ug ml-1 | Compound was tested for antitumor activity against human T-lymphoblast Molt/4F cells | ChEMBL. | 3039140 |
MIC50 (functional) | = 150 ug ml-1 | Compound was tested for antiviral activity against herpes simplex virus( HSV-2-196 strain in primary rabbit kidney cells | ChEMBL. | 3039140 |
MIC50 (functional) | > 150 ug ml-1 | Compound was tested for antiviral activity against herpes simplex virus(thymidine kinase deficient herpes simplex virus ( HSV-1 (B2006) in primary rabbit kidney cells | ChEMBL. | 3039140 |
MIC50 (functional) | = 200 ug ml-1 | Compound was tested for antiviral activity against herpes simplex virus( HSV-2-G) strain in primary rabbit kidney cells | ChEMBL. | 3039140 |
MIC50 (functional) | = 200 ug ml-1 | Compound was tested for antiviral activity against herpes simplex virus( HSV-2-lyons) strain in primary rabbit kidney cells | ChEMBL. | 3039140 |
MIC50 (functional) | > 400 ug ml-1 | Compound was tested for antiviral activity against herpes simplex Vassicular stomatitis in primary rabbit kidney cells | ChEMBL. | 3039140 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.