Detailed information for compound 48130

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 512.467 | Formula: C24H18F6N2O2S
  • H donors: 0 H acceptors: 2 LogP: 4.77 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: C#CCN1N=C2C(C1c1cccc(c1)C(F)(F)F)CS(=O)(=O)C/C/2=C\c1cccc(c1)C(F)(F)F
  • InChi: 1S/C24H18F6N2O2S/c1-2-9-32-22(16-6-4-8-19(12-16)24(28,29)30)20-14-35(33,34)13-17(21(20)31-32)10-15-5-3-7-18(11-15)23(25,26)27/h1,3-8,10-12,20,22H,9,13-14H2/b17-10+
  • InChiKey: ACLRXYMSLUTYDJ-LICLKQGHSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi phospholipase A2-like protein, putative 0.0152 0.181 0.183
Schistosoma mansoni hypothetical protein 0.005 0.0508 0.0799
Echinococcus granulosus geminin 0.0502 0.6296 1
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0012 0.0026 0.0007
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0012 0.0026 0.0026
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0108 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0104 0.1201 0.1212
Onchocerca volvulus 0.0023 0.0166 0.0162
Schistosoma mansoni alpha-1 adrenergic receptor 0.0018 0.0095 0.0142
Loa Loa (eye worm) hypothetical protein 0.0105 0.1209 0.122
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0133 0.0129
Echinococcus multilocularis integrin alpha ps 0.0067 0.0725 0.0707
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.002 0.0124 0.0104
Brugia malayi hypothetical protein 0.0049 0.0497 0.0498
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0046 0.0026
Echinococcus multilocularis serine threonine protein kinase 0.0115 0.1342 0.1324
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0014 0.0049 0.0029
Loa Loa (eye worm) hypothetical protein 0.0104 0.1201 0.1212
Onchocerca volvulus Phospholipase A2 homolog 0.0275 0.3384 0.3895
Schistosoma mansoni phd finger protein 0.0012 0.0023 0.0027
Onchocerca volvulus 0.0018 0.0095 0.0081
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0012 0.0026 0.002
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0156 0.0217
Loa Loa (eye worm) peptidase family M13 containing protein 0.0142 0.1682 0.1699
Echinococcus multilocularis cathepsin L cysteine protease 0.0033 0.0285 0.0266
Brugia malayi oxidoreductase 0.0012 0.0026 0.002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0104 0.1201 0.19
Plasmodium falciparum plasmepsin X 0.0029 0.0238 0.0464
Mycobacterium ulcerans oxidoreductase 0.0012 0.0026 0.0006
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0105 0.1209 0.1413
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0018 0.0095 0.0075
Brugia malayi Dopamine receptor protein 2 0.0018 0.0095 0.0091
Schistosoma mansoni importin beta-1 0.0028 0.0228 0.0353
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.0285 0.0283
Echinococcus granulosus inositol monophosphatase 1 0.0072 0.0784 0.1218
Plasmodium vivax steroid dehydrogenase, putative 0.0012 0.0026 0.0055
Loa Loa (eye worm) hypothetical protein 0.0055 0.0572 0.0574
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0012 0.0026 0.0006
Brugia malayi ORL1-like opioid receptor 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0142 0.1682 0.1699
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.002 0.0124 0.0165
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0046 0.0023
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0095 0.0142
Brugia malayi hypothetical protein 0.0029 0.0238 0.0235
Brugia malayi beta-lactamase family protein 0.0105 0.1209 0.122
Schistosoma mansoni biogenic amine receptor 0.0018 0.0095 0.0142
Schistosoma mansoni nAChR subunit 0.0019 0.0108 0.0162
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0122 0.1432 0.1451
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0108 0.014
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0018 0.0095 0.0142
Loa Loa (eye worm) DR-78 0.0049 0.0497 0.0498
Brugia malayi nuclear receptor RXR 0.0049 0.0497 0.0498
Schistosoma mansoni serine/threonine protein kinase 0.0129 0.1522 0.2411
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0006
Brugia malayi Flap endonuclease-1 0.0025 0.019 0.0187
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Onchocerca volvulus 0.0018 0.0095 0.0081
Brugia malayi Serotonin receptor 0.0018 0.0095 0.0091
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0023 0.0166 0.0146
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0029 0.0238 0.0368
Loa Loa (eye worm) hypothetical protein 0.0142 0.1682 0.1699
Leishmania major cathepsin L-like protease 0.0033 0.0285 0.0269
Toxoplasma gondii aspartyl protease ASP1 0.0122 0.1432 0.1451
Loa Loa (eye worm) AGC/PKN protein kinase 0.002 0.0124 0.012
Schistosoma mansoni inositol monophosphatase 0.0072 0.0784 0.1238
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.0378 0.4707 0.4696
Loa Loa (eye worm) hypothetical protein 0.0138 0.163 0.1646
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0012 0.0026 0.0007
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0095 0.012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0095 0.0142
Schistosoma mansoni neprilysin-2 (M13 family) 0.0097 0.1106 0.1749
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.002 0.0124 0.0104
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0108 0.0103
Schistosoma mansoni retinoic acid receptor RXR 0.0104 0.1201 0.19
Plasmodium falciparum polyprenol reductase, putative 0.0378 0.4707 1
Echinococcus granulosus cathepsin l1 0.0022 0.0147 0.0203
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.019 0.0187
Leishmania major cathepsin L-like protease 0.0033 0.0285 0.0269
Echinococcus multilocularis cathepsin L 0.0017 0.0083 0.0063
Trichomonas vaginalis esterase, putative 0.0105 0.1209 0.1202
Loa Loa (eye worm) carboxylesterase 0.0023 0.0166 0.0162
Loa Loa (eye worm) hypothetical protein 0.0049 0.0497 0.0498
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.0784 0.0776
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0095 0.0142
Loa Loa (eye worm) hypothetical protein 0.0049 0.0497 0.0498
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0644 0.0652
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0166 0.0173
Trypanosoma cruzi cysteine proteinase, putative 0.0017 0.0083 0.0078
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Echinococcus multilocularis somatostatin receptor 0.0018 0.0095 0.0075
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0104 0.1201 0.1212
Plasmodium falciparum cysteine proteinase falcipain 3 0.0033 0.0285 0.0566
Trichomonas vaginalis spcc417.12 protein, putative 0.0023 0.0166 0.0142
Mycobacterium tuberculosis Probable lipase LipD 0.0105 0.1209 0.1413
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0485 0.0486
Loa Loa (eye worm) hypothetical protein 0.0378 0.4707 0.4766
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.002 0.0118 0.0094
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0026 0.0006
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0049 0.0497 0.0498
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0019 0.0108 0.0103
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0012 0.0026 0.0032
Brugia malayi hypothetical protein 0.0049 0.0497 0.0498
Loa Loa (eye worm) oxidoreductase 0.0012 0.0026 0.002
Brugia malayi tailless protein 0.0049 0.0497 0.0498
Loa Loa (eye worm) hypothetical protein 0.0049 0.0497 0.0498
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.005 0.0508 0.0799
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0026 0.0006
Loa Loa (eye worm) hypothetical protein 0.0145 0.1724 0.1742
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0095 0.0075
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.002 0.0126 0.0107
Entamoeba histolytica protein kinase, putative 0.002 0.0124 0.0099
Onchocerca volvulus Cathepsin F homolog 0.0033 0.0285 0.0301
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0012 0.0026 0.0006
Brugia malayi isocitrate dehydrogenase 0.0031 0.0259 0.0257
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0029 0.0238 0.0368
Brugia malayi hypothetical protein 0.0018 0.0095 0.0091
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.002 0.0126 0.0122
Brugia malayi Tachykinin-like peptides receptor 99D 0.0018 0.0095 0.0091
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.019 0.0173
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0083 0.0122
Schistosoma mansoni amine GPCR 0.0018 0.0095 0.0142
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0019 0.0108 0.0088
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0012 0.0026 0.002
Onchocerca volvulus 0.0331 0.4104 0.4729
Loa Loa (eye worm) hypothetical protein 0.0082 0.0923 0.093
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0104 0.1201 0.1882
Echinococcus granulosus dro:myosuppressin receptor 0.0018 0.0095 0.012
Loa Loa (eye worm) hypothetical protein 0.0069 0.0756 0.0761
Brugia malayi hypothetical protein 0.0018 0.0095 0.0091
Onchocerca volvulus 0.0018 0.0095 0.0081
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Brugia malayi Cathepsin L-like precursor 0.0033 0.0285 0.0283
Entamoeba histolytica aspartyl aminopeptidase, putative 0.0069 0.0756 0.0742
Echinococcus granulosus allatostatin A receptor 0.0018 0.0095 0.012
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0108 0.0088
Mycobacterium leprae Probable lipase LipE 0.0105 0.1209 0.5164
Plasmodium vivax aspartyl protease, putative 0.0029 0.0238 0.0505
Mycobacterium tuberculosis Probable oxidoreductase 0.0012 0.0026 0.0007
Onchocerca volvulus 0.0033 0.0285 0.0301
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.002 0.0126 0.0192
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0108 0.014
Loa Loa (eye worm) hypothetical protein 0.0104 0.1201 0.1212
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.002 0.0126 0.0122
Schistosoma mansoni opsin-like receptor 0.0018 0.0095 0.0142
Schistosoma mansoni rac gtpase activating protein 0.0014 0.0049 0.0068
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0046 0.004
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0095 0.0142
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0012 0.0026 0.002
Schistosoma mansoni cathepsin F (C01 family) 0.0033 0.0285 0.0444
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0132 0.0127
Trichomonas vaginalis importin beta-1, putative 0.0023 0.016 0.0136
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.0026 0.0006
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0086 0.0127
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0095 0.0142
Schistosoma mansoni aspartyl aminopeptidase (M18 family) 0.0069 0.0756 0.1193
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0133 0.0129
Onchocerca volvulus 0.0105 0.1209 0.1372
Onchocerca volvulus 0.0033 0.0285 0.0301
Schistosoma mansoni amine GPCR 0.0018 0.0095 0.0142
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0026 0.0012
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0019 0.0108 0.0103
Giardia lamblia Methionine aminopeptidase 0.0045 0.0447 0.09
Echinococcus multilocularis carboxylesterase 5A 0.0138 0.163 0.1613
Echinococcus multilocularis protein kinase c eta type 0.0014 0.0049 0.0029
Trichomonas vaginalis AGC family protein kinase 0.002 0.0124 0.0099
Entamoeba histolytica cysteine protease, putative 0.0017 0.0083 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0063 0.0043
Schistosoma mansoni nAChR subunit 0.0019 0.0108 0.0162
Entamoeba histolytica cysteine protease, putative 0.0017 0.0083 0.0058
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.0781 0.9869 1
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0019 0.0108 0.0103
Mycobacterium tuberculosis Carboxylesterase LipT 0.0023 0.0166 0.0173
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0083 0.0058
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0192 0.2322 0.2348
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.002 0.0126 0.0192
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0095 0.0142
Loa Loa (eye worm) hypothetical protein 0.0032 0.0279 0.0277
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0285 0.0264
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0104 0.1201 0.19
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.002 0.0124 0.0104
Loa Loa (eye worm) hypothetical protein 0.0142 0.1682 0.1699
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0044
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0095 0.0075
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0019 0.0108 0.0088
Schistosoma mansoni hypothetical protein 0.005 0.0508 0.0799
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0259 0.0239
Brugia malayi initiation factor 2-associated protein. 0.0045 0.0447 0.0448
Onchocerca volvulus Protein ultraspiracle homolog 0.0104 0.1201 0.1363
Loa Loa (eye worm) nuclear receptor NHR-67 0.0049 0.0497 0.0498
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0017 0.0086 0.0066
Loa Loa (eye worm) hypothetical protein 0.0113 0.1315 0.1327
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0192 0.2322 0.2348
Loa Loa (eye worm) hypothetical protein 0.0055 0.0572 0.0574
Brugia malayi G protein-coupled receptor 0.0018 0.0095 0.0091
Giardia lamblia Rab geranylgeranyltransferase 0.002 0.0126 0.0215
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0018 0.0095 0.0091
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Schistosoma mansoni hypothetical protein 0.0021 0.0132 0.02
Entamoeba histolytica cysteine protease, putative 0.0017 0.0083 0.0058
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Trypanosoma cruzi phospholipase A1, putative 0.0331 0.4104 0.4155
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.002 0.0126 0.0128
Echinococcus multilocularis flap endonuclease 1 0.0025 0.019 0.017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0095 0.0142
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0012 0.0026 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1458 0.146
Echinococcus granulosus fatty acid amide hydrolase 1 0.0098 0.1129 0.1768
Loa Loa (eye worm) hypothetical protein 0.0145 0.1724 0.1742
Onchocerca volvulus 0.0095 0.1084 0.1227
Schistosoma mansoni BC026374 protein (S09 family) 0.0023 0.0166 0.0254
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0166 0.0254
Schistosoma mansoni retinal dehydrogenase 0.0012 0.0026 0.0032
Echinococcus granulosus NDR protein kinase 0.002 0.0124 0.0165
Echinococcus granulosus 7TM GPCR rhodopsin 0.0018 0.0095 0.012
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0108 0.0103
Schistosoma mansoni hypothetical protein 0.0018 0.0095 0.0142
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0019 0.0108 0.0088
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0007
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0006
Plasmodium vivax aspartyl proteinase, putative 0.0029 0.0238 0.0505
Loa Loa (eye worm) ctsf protein 0.0033 0.0285 0.0283
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0046 0.0455 0.0456
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0104 0.1201 0.1882
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0026 0.0006
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0026 0.0006
Loa Loa (eye worm) aspartyl aminopeptidase 0.0069 0.0756 0.0761
Leishmania major short chain dehydrogenase/reductase, putative 0.0012 0.0026 0.0006
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0108 0.0088
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.002 0.0126 0.0107
Brugia malayi G-protein coupled receptor 0.0018 0.0095 0.0091
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0781 0.9869 1
Echinococcus multilocularis inositol monophosphatase 1 0.0072 0.0784 0.0766
Trypanosoma brucei rac serine-threonine kinase, putative 0.002 0.0124 0.0105
Leishmania major 3-keto-dihydrosphingosine reductase 0.0012 0.0026 0.0006
Brugia malayi hypothetical protein 0.0012 0.0026 0.002
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0018 0.0095 0.0142
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0007
Brugia malayi Protein kinase domain containing protein 0.002 0.0124 0.012
Echinococcus granulosus g protein coupled receptor 0.0018 0.0095 0.012
Onchocerca volvulus 0.0033 0.0285 0.0301
Plasmodium vivax vivapain-3 0.0017 0.0083 0.0176
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0656 0.1033
Echinococcus granulosus protein kinase c eta type 0.0014 0.0049 0.0046
Schistosoma mansoni vav2 0.0014 0.0049 0.0068
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0104 0.1201 0.1882
Loa Loa (eye worm) hypothetical protein 0.0104 0.1201 0.1212
Plasmodium vivax glutamyl-tRNA(Gln) amidotransferase subunit A, putative 0.0012 0.002 0.0043
Schistosoma mansoni methionyl aminopeptidase 2 (M24 family) 0.0045 0.0447 0.0702
Echinococcus multilocularis cysteine protease 0.0033 0.0285 0.0266
Onchocerca volvulus 0.0018 0.0095 0.0081
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0437 0.0418
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0046 0.0041
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.0026 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0044
Plasmodium vivax unspecified product 0.0011 0.0006 0.0012
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0105 0.1209 0.1413
Brugia malayi ecdysone receptor 0.0049 0.0497 0.0498
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0012 0.0026 0.0006
Brugia malayi nuclear receptor NHR-88 0.0049 0.0497 0.0498
Onchocerca volvulus 0.0017 0.0086 0.007
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0108 0.0103
Trypanosoma cruzi metallo-peptidase, Clan MH, Family M20 0.0069 0.0756 0.0761
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0026 0.0032
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0012 0.0026 0.0007
Schistosoma mansoni histamine h1 receptor 0.0018 0.0095 0.0142
Plasmodium vivax vivapain-1 0.0017 0.0083 0.0176
Onchocerca volvulus 0.0019 0.0108 0.0095
Echinococcus granulosus orexin receptor type 2 0.0018 0.0095 0.012
Brugia malayi acetyltransferase, GNAT family protein 0.0284 0.3503 0.3546
Trypanosoma cruzi lanosterol synthase, putative 0.0148 0.1758 0.1776
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Trichomonas vaginalis AGC family protein kinase 0.002 0.0124 0.0099
Plasmodium vivax hypothetical protein, conserved 0.0105 0.1209 0.2568
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.002 0.0126 0.0192
Plasmodium vivax aspartyl protease, putative 0.0029 0.0238 0.0505
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0085 0.0958 0.2036
Onchocerca volvulus 0.0018 0.0095 0.0081
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0012 0.0026 0.002
Schistosoma mansoni hypothetical protein 0.0015 0.0063 0.0091
Echinococcus granulosus neuropeptide receptor A26 0.0464 0.5817 0.9237
Schistosoma mansoni carbonyl reductase 0.0012 0.0026 0.0032
Trichomonas vaginalis inositol monophosphatase, putative 0.0072 0.0784 0.0771
Brugia malayi Inositol-1 0.0072 0.0784 0.0789
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0063 0.0058
Schistosoma mansoni hypothetical protein 0.0014 0.0049 0.0068
Brugia malayi Carboxylesterase family protein 0.0023 0.0166 0.0162
Loa Loa (eye worm) hypothetical protein 0.0055 0.0572 0.0574
Schistosoma mansoni protein farnesyltransferase subunit beta 0.002 0.0126 0.0192
Schistosoma mansoni integrin alpha-ps 0.0035 0.0314 0.049
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0259 0.0239
Loa Loa (eye worm) hypothetical protein 0.0066 0.0713 0.0717
Loa Loa (eye worm) hypothetical protein 0.0029 0.0238 0.0235
Loa Loa (eye worm) hypothetical protein 0.0145 0.1724 0.1742
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0033 0.0285 0.0283
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0108 0.014
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0259 0.0284
Echinococcus multilocularis N chimaerin 0.0014 0.0049 0.0029
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0437 0.0437
Loa Loa (eye worm) hypothetical protein 0.0049 0.0497 0.0498
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0285 0.0264
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0018 0.0095 0.0075
Brugia malayi hypothetical protein 0.0018 0.0095 0.0091
Loa Loa (eye worm) TYRA-2 protein 0.0018 0.0095 0.0091
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.002 0.0126 0.0102
Loa Loa (eye worm) hypothetical protein 0.0686 0.865 0.8764
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1458 0.146
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0092 0.1048 0.103
Leishmania major short chain dehydrogenase, putative 0.0012 0.0026 0.0006
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0012 0.0026 0.0032
Trichomonas vaginalis AGC family protein kinase 0.002 0.0124 0.0099
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0259 0.0239
Schistosoma mansoni hypothetical protein 0.0032 0.0279 0.0434
Loa Loa (eye worm) acetylcholinesterase 1 0.0138 0.163 0.1646
Loa Loa (eye worm) TK/EPH protein kinase 0.0167 0.2002 0.2024
Onchocerca volvulus 0.0048 0.0483 0.053
Trypanosoma cruzi cysteine peptidase, putative 0.0124 0.1458 0.1473
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1458 0.146
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0095 0.0142
Entamoeba histolytica cysteine protease, putative 0.0017 0.0083 0.0058
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0012 0.0026 0.002
Echinococcus multilocularis endothelin converting enzyme 1 0.0192 0.2322 0.2307
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0026 0.0006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0284 0.0263
Plasmodium vivax methionine aminopeptidase 2, putative 0.0045 0.0447 0.095
Plasmodium falciparum steroid dehydrogenase, putative 0.0012 0.0026 0.0012
Plasmodium falciparum importin beta, putative 0.0028 0.0228 0.0444
Trichomonas vaginalis AGC family protein kinase 0.002 0.0124 0.0099
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.002 0.0126 0.0102
Chlamydia trachomatis glutamyl-tRNA(Gln) amidotransferase subunit A 0.0012 0.002 0.5
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0026 0.0032
Onchocerca volvulus 0.0104 0.1201 0.1363
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0437 0.0664
Brugia malayi dehydrogenases, short chain protein 2 0.0012 0.0026 0.002
Onchocerca volvulus 0.0033 0.0285 0.0301
Brugia malayi nuclear receptor NHR-88 0.0104 0.1201 0.1212
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0045 0.0447 0.0434
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0012 0.0026 0.0026
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0095 0.012
Mycobacterium tuberculosis Probable aminopeptidase PepC 0.0069 0.0756 0.0875
Echinococcus granulosus fmrfamide receptor 0.0018 0.0095 0.012
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0012 0.0026 0.0007
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0072 0.0784 0.0771
Schistosoma mansoni thyroid hormone receptor 0.0104 0.1201 0.19
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0012 0.0026 0.0009
Giardia lamblia Histone acetyltransferase GCN5 0.0076 0.084 0.1738
Echinococcus granulosus N chimaerin 0.0014 0.0049 0.0046
Echinococcus multilocularis retinol dehydrogenase 13 0.0012 0.0026 0.0006
Loa Loa (eye worm) hypothetical protein 0.0103 0.1191 0.1202
Plasmodium vivax protein kinase, putative 0.0012 0.0017 0.0035
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0095 0.0142
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0014 0.0049 0.0068
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0104 0.1201 0.19
Mycobacterium leprae conserved hypothetical protein 0.0105 0.1209 0.5164
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.136 0.1372
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0644 0.0633
Echinococcus multilocularis unc 13 (munc13) 0.0017 0.0086 0.0066
Brugia malayi Steroid receptor seven-up type 2 0.0104 0.1201 0.1212
Entamoeba histolytica cysteine protease, putative 0.0017 0.0083 0.0058
Echinococcus granulosus Diacylglycerol kinase theta 0.0014 0.0049 0.0046
Entamoeba histolytica cysteine protease, putative 0.0017 0.0083 0.0058
Trypanosoma cruzi phospholipase A1, putative 0.0331 0.4104 0.4155
Mycobacterium leprae probable zinc metalloprotease 0.0192 0.2322 1
Schistosoma mansoni neuropeptide receptor 0.0018 0.0095 0.0142
Brugia malayi Cation transporter family protein 0.0019 0.0108 0.0103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0095 0.0142
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0224 0.0325
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Plasmodium vivax aspartyl protease, putative 0.0029 0.0238 0.0505
Plasmodium vivax unspecified product 0.0017 0.0083 0.0176
Echinococcus multilocularis Diacylglycerol kinase theta 0.0014 0.0049 0.0029
Echinococcus granulosus ephrin type A receptor 4 A 0.0131 0.1547 0.2433
Brugia malayi cathepsin L-like precursor 0.0022 0.0147 0.0143
Echinococcus multilocularis protein kinase c iota type 0.0034 0.0305 0.0285
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0026 0.002
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0041 0.0388 0.0374
Loa Loa (eye worm) oxidoreductase 0.0012 0.0026 0.002
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0029 0.0238 0.0368
Schistosoma mansoni biogenic amine receptor 0.0018 0.0095 0.0142
Echinococcus granulosus integrin alpha ps 0.0032 0.0279 0.0412
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0029 0.0238 0.0241
Schistosoma mansoni nuclear receptor 0.0049 0.0497 0.078
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.002 0.0124 0.012
Echinococcus granulosus Nuclear hormone receptor HR96 0.0049 0.0497 0.076
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0006
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0012 0.0026 0.0007
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0656 0.0659
Loa Loa (eye worm) fibroinase 0.0033 0.0285 0.0283
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0285 0.0264
Entamoeba histolytica cysteine protease, putative 0.0017 0.0083 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0095 0.0142
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0026 0.0032
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0228 0.0211
Onchocerca volvulus Cathepsin L homolog 0.0033 0.0285 0.0301
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.029 0.0288
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0497 0.078
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0126 0.0122
Echinococcus granulosus raf serine:threonine protein kinase 0.0016 0.0067 0.0075
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.002 0.0124 0.012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0108 0.0103
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0041 0.0388 0.0374
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.0026
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Loa Loa (eye worm) RNA binding protein 0.0061 0.0656 0.0659
Brugia malayi larval opioid receptor 0.0018 0.0095 0.0091
Echinococcus multilocularis FTZ F1 alpha 0.0104 0.1201 0.1183
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.0069 0.0756 0.0742
Brugia malayi putative amidase 0.0012 0.002 0.0014
Echinococcus granulosus importin subunit beta 1 0.0028 0.0228 0.0332
Echinococcus granulosus tar DNA binding protein 0.0061 0.0656 0.1013
Schistosoma mansoni serine/threonine kinase 0.002 0.0124 0.0187
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0055 0.0572 0.09
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0285 0.0264
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.002
Brugia malayi Bromodomain containing protein 0.0082 0.0915 0.0921
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0285 0.0264
Schistosoma mansoni atypical protein kinase C 0.0034 0.0305 0.0475
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0033 0.0285 0.0566
Schistosoma mansoni thyroid hormone receptor 0.0104 0.1201 0.19
Loa Loa (eye worm) hypothetical protein 0.0142 0.1682 0.1699
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0012 0.0026 0.0007
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0026 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0104 0.1201 0.1212
Plasmodium falciparum M18 aspartyl aminopeptidase 0.0069 0.0756 0.1571
Trypanosoma brucei methionine aminopeptidase 2, putative 0.0045 0.0447 0.0434
Schistosoma mansoni biogenic amine receptor 0.0018 0.0095 0.0142
Leishmania major cathepsin L-like protease 0.0124 0.1458 0.146
Entamoeba histolytica diacylglycerol kinase, putative 0.0014 0.0049 0.0023
Brugia malayi Importin beta-1 subunit 0.0028 0.0228 0.0225
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0497 0.0478
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.0026 0.0006
Schistosoma mansoni hypothetical protein 0.0015 0.0063 0.0091
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0104 0.1201 0.1183
Mycobacterium ulcerans zinc metalloprotease 0.0192 0.2322 0.2337
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0781 0.9869 1
Entamoeba histolytica protein kinase, putative 0.002 0.0124 0.0099
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0156 0.0239
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Mycobacterium tuberculosis Conserved protein 0.0105 0.1209 0.1413
Trypanosoma brucei developmentally regulated phosphoprotein 0.0116 0.1356 0.1357
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Echinococcus granulosus neuropeptide receptor 0.0018 0.0095 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0284 0.0263
Brugia malayi nuclear hormone receptor 0.0049 0.0497 0.0498
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0095 0.012
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0116 0.1356 0.2129
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.019 0.0351
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0095 0.0075
Echinococcus granulosus BC026374 protein S09 family 0.0023 0.0166 0.0232
Echinococcus granulosus serotonin receptor 0.0018 0.0095 0.012
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0104 0.1201 0.19
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Loa Loa (eye worm) amidase 0.0012 0.002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0285 0.0264
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0026 0.0006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0437 0.0685
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0012 0.0026 0.0012
Plasmodium falciparum plasmepsin IX 0.0029 0.0238 0.0464
Schistosoma mansoni hypothetical protein 0.0018 0.0095 0.0142
Leishmania major cathepsin L-like protease 0.0124 0.1458 0.146
Schistosoma mansoni hypothetical protein 0.03 0.3714 0.5895
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0006
Brugia malayi hypothetical protein 0.0012 0.0026 0.002
Trypanosoma brucei aspartyl aminopeptidase, putative 0.0069 0.0756 0.0748
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.002
Entamoeba histolytica aminopeptidase, putative 0.0069 0.0756 0.0742
Plasmodium falciparum plasmepsin IV 0.0122 0.1432 0.3012
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0026 0.0032
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.0033 0.0284 0.0263
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.0026 0.0006
Echinococcus multilocularis aspartyl aminopeptidase 0.0069 0.0756 0.0738
Entamoeba histolytica hypothetical protein 0.0378 0.4707 0.4755
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Loa Loa (eye worm) hypothetical protein 0.0049 0.0497 0.0498
Loa Loa (eye worm) hypothetical protein 0.0023 0.0166 0.0162
Brugia malayi nuclear hormone receptor 0.0104 0.1201 0.1212
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.016 0.0136
Toxoplasma gondii carbonyl reductase 1, putative 0.0012 0.0026 0.0026
Echinococcus multilocularis RNA directed DNA polymerase 0.0092 0.1048 0.103
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0026 0.0032
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Brugia malayi protein kinase C3,putative 0.0015 0.0054 0.0049
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0012 0.0026 0.0006
Trichomonas vaginalis D-aminoacylase, putative 0.0105 0.1209 0.1202
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0104 0.1201 0.1212
Schistosoma mansoni coup transcription factor 0.0104 0.1201 0.19
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0019 0.0108 0.0103
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0083 0.0078
Entamoeba histolytica steroid 5-alpha reductase, putative 0.0781 0.9869 1
Leishmania major geranylgeranyltransferase, putative 0.002 0.0126 0.0108
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0108 0.0103
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.0784 0.0789
Brugia malayi Cathepsin L-like precursor 0.0033 0.0285 0.0283
Schistosoma mansoni hypothetical protein 0.0502 0.6296 1
Entamoeba histolytica cysteine protease, putative 0.0017 0.0083 0.0058
Brugia malayi hypothetical protein 0.0018 0.0095 0.0091
Mycobacterium ulcerans dehydrogenase 0.0012 0.0026 0.0006
Loa Loa (eye worm) oxidoreductase 0.0012 0.0026 0.002
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0012 0.0026 0.002
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.019 0.0193
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Onchocerca volvulus 0.0033 0.0285 0.0301
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0083 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1458 0.146
Toxoplasma gondii aspartyl protease 0.0029 0.0238 0.0241
Trypanosoma cruzi amidase, putative 0.0012 0.002 0.0014
Echinococcus granulosus Protein kinase C brain isozyme 0.0129 0.1522 0.2394
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0378 0.4707 0.4755
Brugia malayi hypothetical protein 0.0018 0.0095 0.0091
Echinococcus granulosus zinc finger protein 0.0026 0.0206 0.0297
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Loa Loa (eye worm) oxidoreductase 0.0012 0.0026 0.002
Brugia malayi follicle stimulating hormone receptor 0.0247 0.3035 0.3071
Onchocerca volvulus 0.0049 0.0497 0.0546
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0019 0.0108 0.0103
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0012 0.0026 0.0006
Leishmania major dehydrogenase-like protein 0.0012 0.0026 0.0006
Schistosoma mansoni integrin alpha 0.0149 0.178 0.2821
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0781 0.9869 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Trypanosoma cruzi protein farnesyltransferase, putative 0.002 0.0126 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0284 0.0263
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.0781 0.9869 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0095 0.012
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0095 0.0075
Echinococcus multilocularis tumor protein p63 0.0328 0.407 0.4058
Mycobacterium ulcerans esterase/lipase LipP 0.0105 0.1209 0.1207
Onchocerca volvulus 0.013 0.1529 0.1743
Entamoeba histolytica 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein 0.0378 0.4707 0.4755
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0192 0.2322 0.3682
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0259 0.0262
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0259 0.0262
Leishmania major sterol 24-c-methyltransferase, putative 0.0212 0.2584 0.2603
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0285 0.0264
Loa Loa (eye worm) hypothetical protein 0.0104 0.1201 0.1212
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.002 0.0126 0.0122
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0108 0.0088
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0019 0.0108 0.0162
Brugia malayi Bromodomain containing protein 0.0045 0.0446 0.0446
Echinococcus granulosus GPCR family 2 0.0015 0.0063 0.0069
Onchocerca volvulus 0.0018 0.0095 0.0081
Brugia malayi ecdysteroid receptor 0.0104 0.1201 0.1212
Echinococcus granulosus alpha 1A adrenergic receptor 0.0018 0.0095 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0285 0.0264
Schistosoma mansoni aspartyl aminopeptidase (M18 family) 0.0069 0.0756 0.1193
Schistosoma mansoni fatty-acid amide hydrolase 0.0012 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0049 0.0497 0.0498
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0026 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1458 0.146
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0228 0.0209
Brugia malayi Nuclear hormone receptor-like 1 0.0055 0.0572 0.0574
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0007
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0007
Echinococcus multilocularis BC026374 protein (S09 family) 0.0023 0.0166 0.0146
Schistosoma mansoni pyruvate dehydrogenase 0.0116 0.1356 0.2147
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.0033 0.0284 0.0263
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0012 0.0026 0.0006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0105 0.1209 0.1913
Loa Loa (eye worm) hypothetical protein 0.0035 0.0314 0.0313
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0104 0.1201 0.1212
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0083 0.0058
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.002 0.0126 0.0102
Mycobacterium ulcerans short chain dehydrogenase 0.0279 0.3442 0.3475
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0108 0.0103
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0378 0.4707 0.7473
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0049 0.0501 0.0502
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1458 0.146
Echinococcus granulosus neuropeptide FF receptor 2 0.0018 0.0095 0.012
Echinococcus multilocularis transient receptor potential cation channel 0.0012 0.0026 0.0006
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0285 0.0264
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0049 0.0497 0.0498
Schistosoma mansoni ephrin receptor 0.0131 0.1547 0.245
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0259 0.055
Brugia malayi Cation transporter family protein 0.0019 0.0108 0.0103
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0108 0.014
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0212 0.2584 0.2603
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0012 0.0026 0.002
Schistosoma mansoni nAChR subunit 0.0019 0.0108 0.0162
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0095 0.012
Brugia malayi Cathepsin L-like precursor 0.0033 0.0285 0.0283
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.1209 0.122
Mycobacterium ulcerans carveol-like dehydrogenase 0.0012 0.0026 0.0006
Leishmania major short chain dehydrogenase-like protein 0.0012 0.0026 0.0006
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0023 0.0166 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0104 0.1201 0.1212
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0018 0.0095 0.0075
Loa Loa (eye worm) platelet-activating factor acetylhydrolase 0.0331 0.4104 0.4155
Schistosoma mansoni flap endonuclease-1 0.0023 0.0159 0.0244
Brugia malayi Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II family protein 0.0331 0.4104 0.4155
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0083 0.0122
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0033 0.0285 0.0283
Echinococcus granulosus histone acetyltransferase myst3 0.0012 0.0023 0.0004
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0018 0.0095 0.0142
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0046 0.0041
Mycobacterium leprae PROBABLE AMINOPEPTIDASE PEPC 0.0069 0.0756 0.3199
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0012 0.0026 0.0007
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0259 0.0239
Echinococcus granulosus cysteine protease 0.0017 0.0083 0.01
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0095 0.0142
Echinococcus multilocularis raf serine:threonine protein kinase 0.0016 0.0067 0.0047
Schistosoma mansoni hypothetical protein 0.0015 0.0063 0.0091
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0044
Leishmania major hypothetical protein, conserved 0.0105 0.1209 0.1207
Trichomonas vaginalis AGC family protein kinase 0.002 0.0124 0.0099
Brugia malayi Protein kinase c protein 2 0.011 0.1272 0.1284
Echinococcus granulosus cathepsin l cysteine peptidase 0.0033 0.0285 0.0423
Schistosoma mansoni unc-13 (munc13) 0.0017 0.0086 0.0128
Leishmania major importin beta-1 subunit, putative 0.0023 0.016 0.0142
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0285 0.0264
Schistosoma mansoni cathepsin D (A01 family) 0.0214 0.261 0.4139
Onchocerca volvulus 0.0018 0.0095 0.0081
Brugia malayi Aspartyl aminopeptidase 0.0069 0.0756 0.0761
Loa Loa (eye worm) hypothetical protein 0.002 0.0124 0.012
Loa Loa (eye worm) aspartyl protease 6 0.0029 0.0238 0.0235
Echinococcus multilocularis integrin alpha ps 0.0032 0.0279 0.0259
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Onchocerca volvulus 0.0049 0.0497 0.0546
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0012 0.0026 0.0026
Trypanosoma brucei phospholipase A1, putative 0.0331 0.4104 0.4146
Trypanosoma brucei hypothetical protein, conserved 0.0105 0.1209 0.1207
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1458 0.146
Loa Loa (eye worm) hypothetical protein 0.0106 0.1229 0.124
Echinococcus granulosus fatty acid amide hydrolase 1 0.0098 0.1129 0.1768
Brugia malayi Dopamine receptor 0.0018 0.0095 0.0091
Leishmania major hypothetical protein, conserved 0.0012 0.0026 0.0006
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0108 0.014
Brugia malayi Protein kinase domain containing protein 0.002 0.0124 0.012
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0006
Schistosoma mansoni nAChR subunit 0.0019 0.0108 0.0162
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0029 0.0238 0.0368
Brugia malayi nuclear receptor NHR-67 0.0049 0.0497 0.0498
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0095 0.0075
Brugia malayi Serotonin receptor 0.0018 0.0095 0.0091
Plasmodium falciparum methionine aminopeptidase 2 0.0045 0.0447 0.0912
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.019 0.0187
Echinococcus multilocularis ecdysone induced protein 78C 0.0104 0.1201 0.1183
Loa Loa (eye worm) oxidoreductase 0.0012 0.0026 0.002
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0086 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0147 0.0123
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0012 0.0026 0.002
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.002 0.0124 0.012
Brugia malayi hypothetical protein 0.0055 0.0572 0.0574
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.0026 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0055 0.0572 0.0574
Loa Loa (eye worm) hypothetical protein 0.0038 0.0358 0.0357
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0041 0.0388 0.0393
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0015 0.0054 0.0049
Brugia malayi excitatory GABA receptor EXP-1A 0.0019 0.0108 0.0103
Mycobacterium tuberculosis Conserved protein 0.0105 0.1209 0.1413
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0327 0.0308
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0378 0.4707 0.4766
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0104 0.1201 0.1183
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0041 0.0388 0.0388
Onchocerca volvulus 0.0023 0.0166 0.0162
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0049 0.0497 0.0546
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0095 0.0075
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0083 0.0122
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Echinococcus granulosus methionyl aminopeptidase 2 0.0045 0.0447 0.0681
Leishmania major hypothetical protein, conserved 0.0015 0.0063 0.0044
Schistosoma mansoni pyruvate dehydrogenase 0.011 0.1273 0.2015
Schistosoma mansoni neuroligin 3 (S09 family) 0.0023 0.0166 0.0254
Echinococcus granulosus somatostatin receptor 0.0018 0.0095 0.012
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0047 0.0471 0.0477
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0018 0.0095 0.0075
Loa Loa (eye worm) hypothetical protein 0.002 0.0126 0.0122
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0067 0.0097
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0237 0.024
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0012 0.0026 0.0025
Brugia malayi conserved hypotetical protein 0.0049 0.0497 0.0498
Plasmodium falciparum histone acetyltransferase GCN5 0.0076 0.084 0.1749
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.0719 0.07
Plasmodium falciparum 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0378 0.4707 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0285 0.0264
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0019 0.0108 0.0103
Schistosoma mansoni nAChR subunit 0.0019 0.0108 0.0162
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0228 0.0231
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0237 0.0218
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0072 0.0784 0.0771
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0104 0.1201 0.1212
Brugia malayi AKH receptor 0.0018 0.0095 0.0091
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Trichomonas vaginalis D-aminoacylase, putative 0.0105 0.1209 0.1202
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0026 0.0009
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.002 0.0126 0.0102
Brugia malayi RhoGEF domain containing protein 0.0014 0.0049 0.0044
Brugia malayi S-adenosyl-methionine cycloartenol-C24-methyltransferase 0.0103 0.1191 0.1202
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0055 0.0572 0.09
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.0784 0.0776
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0285 0.0264
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0656 0.1033
Echinococcus multilocularis acetylcholinesterase 0.0138 0.163 0.1613
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0259 0.0243
Loa Loa (eye worm) integrin alpha pat-2 0.023 0.2816 0.2849
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0126 0.0102
Onchocerca volvulus 0.0023 0.0166 0.0162
Trypanosoma cruzi short chain dehydrogenase, putative 0.0012 0.0026 0.002
Plasmodium falciparum cysteine proteinase falcipain 1 0.0017 0.0083 0.0134
Schistosoma mansoni nuclear hormone receptor 0.0104 0.1201 0.19
Trichomonas vaginalis penicillin-binding protein, putative 0.0105 0.1209 0.1202
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0095 0.0091
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0018 0.0095 0.0081
Mycobacterium tuberculosis Probable oxidoreductase 0.0012 0.0026 0.0007
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0108 0.0088
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Trypanosoma brucei Sterol methyltransferase, putative 0.0212 0.2584 0.2603
Loa Loa (eye worm) hypothetical protein 0.0022 0.0147 0.0143
Echinococcus multilocularis neuropeptide FF receptor 2 0.0018 0.0095 0.0075
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0437 0.0664
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0095 0.0142
Brugia malayi beta-lactamase 0.0105 0.1209 0.122
Schistosoma mansoni bromodomain containing protein 0.0011 0.0011 0.0008
Trypanosoma cruzi lanosterol synthase, putative 0.0148 0.1758 0.1776
Brugia malayi G-protein coupled receptor 0.0018 0.0095 0.0091
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0122 0.1432 0.1428
Onchocerca volvulus 0.0029 0.0238 0.0245
Trypanosoma brucei protein farnesyltransferase beta subunit 0.002 0.0126 0.0108
Onchocerca volvulus Cathepsin L homolog 0.0033 0.0285 0.0301
Echinococcus granulosus histone acetyltransferase KAT2B 0.0085 0.0958 0.1495
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0049 0.0497 0.0478
Echinococcus multilocularis allatostatin A receptor 0.0018 0.0095 0.0075
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0072 0.0784 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0105 0.1209 0.122
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0012 0.0026 0.0007
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0116 0.1356 0.1339
Echinococcus multilocularis geminin 0.0502 0.6296 0.6288
Plasmodium falciparum plasmepsin VIII, putative 0.0029 0.0238 0.0464
Onchocerca volvulus 0.0331 0.4104 0.4729
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0095 0.0075
Echinococcus granulosus para nitrobenzyl esterase 0.0023 0.0166 0.0232
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0082 0.0914 0.1062
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.002 0.0126 0.0107
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0029 0.0238 0.0368
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0012 0.0026 0.0009
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0046 0.0026
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0133 0.0115
Echinococcus granulosus protein kinase C gamma type 0.0115 0.1342 0.2106
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0105 0.1209 0.122
Mycobacterium tuberculosis Probable oxidoreductase 0.0279 0.3442 0.4066
Loa Loa (eye worm) hypothetical protein 0.0023 0.0166 0.0162
Plasmodium vivax SET domain protein, putative 0.0029 0.0237 0.0504
Brugia malayi Phospholipase A2 family protein 0.0686 0.865 0.8764
Brugia malayi photoreceptor-specific nuclear receptor 0.0104 0.1201 0.1212
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0015 0.0054 0.0055
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0378 0.4707 0.4755
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0095 0.0075
Echinococcus granulosus g protein coupled receptor 0.0018 0.0095 0.012
Onchocerca volvulus 0.0018 0.0095 0.0081
Echinococcus multilocularis serotonin receptor 0.0018 0.0095 0.0075
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0085 0.0958 0.0947
Loa Loa (eye worm) hypothetical protein 0.0017 0.0086 0.0082
Echinococcus multilocularis G protein coupled receptor 139 0.0018 0.0095 0.0075
Schistosoma mansoni netrin receptor unc5 0.0014 0.0046 0.0063
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0018 0.0095 0.0075
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0466 0.0731
Loa Loa (eye worm) melatonin receptor type 1A 0.0018 0.0095 0.0091
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0023 0.0166 0.0232
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.002 0.0126 0.0102
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0669 0.8436 1
Plasmodium falciparum plasmepsin III 0.0029 0.0238 0.0464
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0049 0.0497 0.078
Trypanosoma cruzi cysteine peptidase, putative 0.0033 0.0285 0.0283
Trypanosoma cruzi major cysteine proteinase, putative 0.0098 0.1118 0.1128
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0095 0.0075
Onchocerca volvulus 0.0018 0.0095 0.0081
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0212 0.2584 0.2614
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0012 0.0026 0.0007
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0033 0.0285 0.0566
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0012 0.0026 0.002
Leishmania major short chain dehydrogenase, putative 0.0012 0.0026 0.0006
Trichomonas vaginalis AGC family protein kinase 0.002 0.0124 0.0099
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Treponema pallidum aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0012 0.002 0.5
Schistosoma mansoni neuropeptide f receptor 76f 0.0018 0.0095 0.0142
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0026 0.0006
Echinococcus granulosus protein kinase c epsilon type 0.0037 0.0342 0.0513
Brugia malayi orphan nuclear receptor NR2E1 0.0049 0.0497 0.0498
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.016 0.0156
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.0026 0.0006
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.002 0.0126 0.0122
Entamoeba histolytica cysteine protease, putative 0.0017 0.0083 0.0058
Echinococcus granulosus steroid dehydrogenase 0.0012 0.0026 0.0009
Echinococcus granulosus Ankyrin 0.0014 0.0047 0.0043
Entamoeba histolytica trans-2,3-enoyl-CoA reductase, putative 0.0378 0.4707 0.4755
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0644 0.1014
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0018 0.0095 0.012
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0054 0.0077
Loa Loa (eye worm) inositol-1 0.0072 0.0784 0.0789
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0095 0.0142
Schistosoma mansoni cathepsin F (C01 family) 0.0033 0.0285 0.0444
Brugia malayi hypothetical protein 0.0023 0.0166 0.0162
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Leishmania major hypothetical protein, conserved 0.0012 0.0026 0.0006
Echinococcus multilocularis para nitrobenzyl esterase 0.0023 0.0166 0.0146
Trypanosoma cruzi phospholipase A2-like protein, putative 0.0152 0.181 0.183
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0122 0.1432 0.2249
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0095 0.0075
Mycobacterium tuberculosis Probable oxidoreductase 0.0012 0.0026 0.0007
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0098 0.1129 0.1112
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0044
Brugia malayi ephrin receptor 1 precursor 0.0063 0.0669 0.0672
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0497 0.078
Echinococcus granulosus carboxylesterase 5A 0.0138 0.163 0.2565
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0237 0.0368
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.019 0.0404
Echinococcus multilocularis neuropeptide receptor A26 0.0464 0.5817 0.5808
Echinococcus granulosus death domain containing protein 0.0014 0.0046 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0342 0.0535
Onchocerca volvulus 0.0018 0.0095 0.0081
Schistosoma mansoni hypothetical protein 0.0018 0.0095 0.0142
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0166 0.0254
Echinococcus multilocularis cathepsin L cysteine protease 0.0033 0.0285 0.0266
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0108 0.0162
Echinococcus multilocularis conserved hypothetical protein 0.0012 0.0026 0.0006
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0133 0.0283
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0781 0.9869 1
Brugia malayi aspartic protease BmAsp-2, identical 0.0029 0.0238 0.0235
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0026 0.0032
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0046 0.0455 0.0436
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0063 0.0069
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0012 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Schistosoma mansoni memapsin-2 (A01 family) 0.0029 0.0238 0.0368
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0018 0.0095 0.0142
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0095 0.0075
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0095 0.0075
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0095 0.0075
Leishmania major cysteine peptidase A (CPA) 0.0033 0.0285 0.0269
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.0026
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0012 0.0026 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0237 0.0368
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0192 0.2322 0.2348
Schistosoma mansoni cathepsin D (A01 family) 0.0214 0.261 0.4139
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0259 0.0257
Onchocerca volvulus 0.0018 0.0095 0.0081
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0006
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0063 0.0058
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0055 0.0572 0.088
Echinococcus multilocularis orexin receptor type 2 0.0018 0.0095 0.0075
Brugia malayi Cathepsin L-like cysteine proteinase 0.0022 0.0147 0.0143
Schistosoma mansoni carbonyl reductase 0.0012 0.0026 0.0032
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0018 0.0095 0.012
Brugia malayi RhoGAP domain containing protein 0.0014 0.0049 0.0044
Loa Loa (eye worm) hypothetical protein 0.0049 0.0497 0.0498
Onchocerca volvulus 0.0022 0.0147 0.0141
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0026 0.0032
Loa Loa (eye worm) hypothetical protein 0.0055 0.0572 0.0574
Echinococcus granulosus FTZ F1 alpha 0.0104 0.1201 0.1882
Brugia malayi Variant SH3 domain containing protein 0.0014 0.0049 0.0044
Echinococcus granulosus histone acetyltransferase KAT2B 0.0273 0.3372 0.534
Mycobacterium tuberculosis Conserved protein 0.0105 0.1209 0.1413
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0644 0.0741
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0026 0.0006
Echinococcus multilocularis sex peptide receptor 0.0018 0.0095 0.0075
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0104 0.1201 0.1882
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0105 0.1209 0.122
Brugia malayi hypothetical protein 0.0055 0.0572 0.0574
Brugia malayi neuropeptide F receptor 0.0018 0.0095 0.0091
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0018 0.0095 0.0091
Schistosoma mansoni hypothetical protein 0.0014 0.0046 0.0063
Echinococcus granulosus tachykinin peptides receptor 99D 0.0018 0.0095 0.012
Brugia malayi RNA, U transporter 1 0.008 0.0892 0.0899
Echinococcus granulosus synaptic glycoprotein sc2 0.0378 0.4707 0.7468
Schistosoma mansoni inositol monophosphatase 0.0072 0.0784 0.1238
Echinococcus granulosus WW domain containing oxidoreductase 0.0012 0.0026 0.0009
Brugia malayi neuropeptide F receptor 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0055 0.0572 0.0574
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0006
Brugia malayi aspartic protease BmAsp-1, identical 0.0029 0.0238 0.0235
Entamoeba histolytica cysteine protease, putative 0.0017 0.0083 0.0058
Echinococcus granulosus endothelin converting enzyme 1 0.0192 0.2322 0.3668
Brugia malayi Uncoordinated protein 44 0.0014 0.0046 0.004
Schistosoma mansoni neprilysin 0.005 0.0508 0.0799
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0095 0.012
Brugia malayi Ras association domain family 1 isoform A 0.0014 0.0049 0.0044
Plasmodium vivax farnesyltransferase beta subunit, putative 0.002 0.0126 0.0269
Trypanosoma brucei aspartyl aminopeptidase, putative 0.0069 0.0756 0.0748
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0019 0.0108 0.0103
Plasmodium vivax geranylgeranyltransferase, putative 0.002 0.0126 0.0269
Loa Loa (eye worm) beta-lactamase 0.0105 0.1209 0.122
Loa Loa (eye worm) acetyltransferase 0.0284 0.3503 0.3546
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0015 0.0054 0.0034
Echinococcus granulosus cathepsin L 0.0017 0.0083 0.01
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0026 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0378 0.4707 0.4755
Loa Loa (eye worm) RasGEF domain-containing protein 0.0014 0.0049 0.0044
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0247 0.3035 0.3071
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0006
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0017 0.0086 0.0106
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0018 0.0095 0.012
Leishmania major cathepsin L-like protease 0.0033 0.0285 0.0269
Loa Loa (eye worm) hypothetical protein 0.0022 0.0147 0.0143
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0033 0.0285 0.0266
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0284 0.3503 0.556
Loa Loa (eye worm) hypothetical protein 0.0049 0.0497 0.0498
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0104 0.1201 0.1212
Brugia malayi dehydrogenases, short chain protein 9 0.0012 0.0026 0.002
Brugia malayi beta-lactamase family protein 0.0105 0.1209 0.122
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0212 0.2584 0.2614
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0781 0.9869 1
Echinococcus multilocularis snurportin 1 0.03 0.3714 0.3701
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0095 0.012
Onchocerca volvulus 0.0331 0.4104 0.4729
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.002 0.0124 0.0165
Onchocerca volvulus 0.0023 0.0166 0.0162
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0466 0.0731
Echinococcus multilocularis ephrin type A receptor 4 A 0.0131 0.1547 0.153
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Echinococcus granulosus protein kinase c iota type 0.0034 0.0305 0.0454
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0108 0.014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Brugia malayi Retinol dehydrogenase 12 0.0012 0.0026 0.002
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0012 0.0026 0.0032
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0019 0.0108 0.0162
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0097 0.1106 0.1749
Leishmania major cathepsin L-like protease 0.0124 0.1458 0.146
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Leishmania major hypothetical protein, conserved 0.0012 0.0026 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0095 0.0142
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.002 0.0124 0.012
Brugia malayi RNA binding protein 0.0061 0.0656 0.0659
Echinococcus multilocularis serine:threonine protein kinase 38 0.002 0.0124 0.0104
Loa Loa (eye worm) hypothetical protein 0.002 0.0126 0.0122
Entamoeba histolytica cysteine protease, putative 0.0017 0.0083 0.0058
Schistosoma mansoni bromodomain containing protein 0.007 0.0765 0.1207
Echinococcus multilocularis nuclear receptor nhr 48 0.0049 0.0497 0.0478
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0122 0.1432 0.1446
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.002 0.0126 0.0128
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0108 0.0103
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0014 0.0049 0.0068
Plasmodium vivax importin-beta 2, putative 0.0028 0.0228 0.0485
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0055 0.0572 0.0553
Plasmodium falciparum geranylgeranyltransferase, putative 0.002 0.0126 0.0227
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0033 0.0285 0.0264
Echinococcus granulosus myotubularin protein 13 0.0014 0.0049 0.0046
Schistosoma mansoni RAR-like nuclear receptor 0.0104 0.1201 0.19
Echinococcus granulosus Rac GTPase activating protein 1 0.0014 0.0049 0.0046
Loa Loa (eye worm) hypothetical protein 0.0378 0.4707 0.4766
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0259 0.0257
Trichomonas vaginalis set domain proteins, putative 0.0229 0.2799 0.2818
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0012 0.0026 0.0077
Loa Loa (eye worm) hypothetical protein 0.0275 0.3384 0.3426
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0012 0.0026 0.0006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1458 0.146
Loa Loa (eye worm) hypothetical protein 0.0023 0.0166 0.0162
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0104 0.1201 0.1212
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0095 0.012
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0192 0.2322 0.2736
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0012 0.0026 0.0032
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0012 0.0026 0.0007
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0072 0.0784 0.0771
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0049 0.0497 0.0546
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0104 0.1201 0.1882
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0006
Echinococcus granulosus serine:threonine protein kinase N2 0.002 0.0124 0.0165
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0108 0.014
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0071 0.0772 0.0776
Brugia malayi diacylglycerol kinase 0.0014 0.0049 0.0044
Schistosoma mansoni hypothetical protein 0.0015 0.0063 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0124 0.0187
Brugia malayi Carboxylesterase family protein 0.0023 0.0166 0.0162
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Onchocerca volvulus 0.0019 0.0108 0.0095
Echinococcus multilocularis neuroligin 0.0023 0.0166 0.0146
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0015 0.0054 0.0049
Echinococcus multilocularis G-protein coupled receptor, putative 0.0018 0.0095 0.0075
Loa Loa (eye worm) hypothetical protein 0.0105 0.1209 0.122
Leishmania major short chain dehydrogenase/reductase, putative 0.0012 0.0026 0.0006
Loa Loa (eye worm) oxidoreductase 0.0012 0.0026 0.002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0455 0.0714
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0018 0.0095 0.0075
Schistosoma mansoni integrin alpha-ps 0.0067 0.0725 0.1144
Trypanosoma cruzi short chain dehydrogenase, putative 0.0012 0.0026 0.002
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0212 0.2584 0.2614
Echinococcus multilocularis myotubularin protein 13 0.0014 0.0049 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0285 0.0264
Echinococcus granulosus g-protein coupled receptor 0.0018 0.0095 0.012
Echinococcus granulosus hypothetical protein 0.0018 0.0095 0.012
Onchocerca volvulus 0.0033 0.0285 0.0301
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0437 0.0437
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0083 0.0058
Leishmania major oxidoreductase-like protein 0.0012 0.0026 0.0006
Loa Loa (eye worm) LGC-31 protein 0.0019 0.0108 0.0103
Plasmodium vivax plasmepsin IV, putative 0.0122 0.1432 0.3042
Plasmodium falciparum plasmepsin VI 0.0122 0.1432 0.3012
Schistosoma mansoni protein kinase C 0.0017 0.0086 0.0128
Brugia malayi Pre-SET motif family protein 0.0029 0.0237 0.0235
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0116 0.1356 0.1369
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0124 0.0187
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0105 0.1209 0.1207
Trypanosoma cruzi protein farnesyltransferase, putative 0.002 0.0126 0.0122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1458 0.146
Plasmodium vivax 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0378 0.4707 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0104 0.1201 0.1212
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0126 0.0102
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0104 0.1201 0.1212
Trichomonas vaginalis conserved hypothetical protein 0.0378 0.4707 0.4755
Echinococcus granulosus g protein coupled receptor 0.0018 0.0095 0.012
Onchocerca volvulus 0.0105 0.1209 0.1372
Plasmodium falciparum protein farnesyltransferase subunit beta 0.002 0.0126 0.0227
Echinococcus granulosus thyroid hormone receptor alpha 0.0049 0.0497 0.076
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0095 0.0075
Echinococcus granulosus oxidoreductase 0.0012 0.0026 0.0009
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0019 0.0108 0.0162
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0285 0.0264
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0644 0.0633
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0086 0.0105
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0097 0.1106 0.1749
Brugia malayi Death domain containing protein 0.0014 0.0046 0.004
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0095 0.012
Onchocerca volvulus Bile acid receptor homolog 0.0104 0.1201 0.1363
Schistosoma mansoni adenoreceptor 0.0018 0.0095 0.0142
Mycobacterium ulcerans lipase LipD 0.0105 0.1209 0.1207
Plasmodium falciparum plasmepsin VII 0.0029 0.0238 0.0464
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0116 0.1356 0.1339
Toxoplasma gondii oxidoreductase, putative 0.0012 0.0026 0.0026
Entamoeba histolytica diacylglycerol kinase, putative 0.0014 0.0049 0.0023
Loa Loa (eye worm) hypothetical protein 0.0145 0.1724 0.1742
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Schistosoma mansoni fatty-acid amide hydrolase 0.0098 0.1129 0.1786
Mycobacterium tuberculosis Probable esterase LipL 0.0105 0.1209 0.1413
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.002 0.0124 0.0165
Brugia malayi Amidase family protein 0.0012 0.002 0.0014
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0019 0.0108 0.0103
Schistosoma mansoni hypothetical protein 0.005 0.0508 0.0799
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0104 0.1201 0.1212
Schistosoma mansoni cathepsin F (C01 family) 0.0022 0.0147 0.0225
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0026 0.0006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.002 0.0126 0.0227
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0104 0.1201 0.1212
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0012 0.0026 0.002
Echinococcus granulosus integrin alpha 3 0.0114 0.1334 0.2094
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0026 0.0055
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0063 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0104 0.1201 0.1212
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0129 0.1522 0.1505
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0285 0.0264
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.019 0.0173
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0044
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0095 0.012
Trypanosoma cruzi ISWI complex protein 0.0015 0.0063 0.0058
Schistosoma mansoni opsin-like receptor 0.0018 0.0095 0.0142
Echinococcus granulosus acetylcholinesterase 0.0138 0.163 0.2565
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Echinococcus multilocularis thyroid hormone receptor alpha 0.0104 0.1201 0.1183
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0045 0.0447 0.0448
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0049 0.0497 0.0498
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0095 0.1091 0.11
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0014 0.0049 0.0046
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0147 0.0123
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0133 0.0113
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0644 0.0633
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0378 0.4707 0.4755
Loa Loa (eye worm) hypothetical protein 0.0029 0.0238 0.0235
Loa Loa (eye worm) oxidoreductase 0.0012 0.0026 0.002
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0126 0.0102
Echinococcus granulosus Nuclear hormone receptor HR96 0.0049 0.0497 0.076
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0007
Brugia malayi Carboxylesterase family protein 0.0023 0.0166 0.0162
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0644 0.0625
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0012 0.0026 0.0006
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0378 0.4707 0.4759
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0019 0.0108 0.014
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0108 0.0088
Loa Loa (eye worm) dehydrogenase 0.0012 0.0026 0.002
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.002 0.0126 0.017
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0437 0.0418
Plasmodium vivax vivapain-2 0.0033 0.0285 0.0606
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0104 0.1201 0.1183
Trichomonas vaginalis penicillin-binding protein, putative 0.0105 0.1209 0.1202
Schistosoma mansoni hypothetical protein 0.0502 0.6296 1
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0019 0.0108 0.0103
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0327 0.0489
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0108 0.014
Schistosoma mansoni pyruvate dehydrogenase 0.011 0.1273 0.2015
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0029 0.0238 0.0368
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Brugia malayi Cation transporter family protein 0.0019 0.0108 0.0103
Leishmania major hypothetical protein, conserved 0.0012 0.0026 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Leishmania major aspartyl aminopeptidase, putative,metallo-peptidase, Clan MH, Family M20 0.0069 0.0756 0.0748
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0026 0.0009
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0156 0.0136
Echinococcus multilocularis Rac GTPase activating protein 1 0.0014 0.0049 0.0029
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0012 0.0026 0.002
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0064 0.0688 0.0794
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0026 0.0006
Loa Loa (eye worm) initiation factor 2-associated protein 0.0045 0.0447 0.0448
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0095 0.012
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0018 0.0095 0.0091
Brugia malayi hypothetical protein 0.0018 0.0095 0.0091
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0033 0.0285 0.0266
Schistosoma mansoni diacylglycerol kinase theta 0.0014 0.0049 0.0068
Loa Loa (eye worm) carboxylesterase 0.0138 0.163 0.1646
Echinococcus multilocularis integrin alpha ps 0.0067 0.0725 0.0707
Leishmania major pteridine reductase 1 0.0012 0.0026 0.0006
Brugia malayi peptidase family M13 containing protein 0.0047 0.0466 0.0466
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.002 0.0126 0.0128
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0029 0.0238 0.0368
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0086 0.0127
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0111 0.1284 0.1284
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0104 0.1201 0.1212
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0018 0.0095 0.0091
Leishmania major lanosterol synthase, putative 0.0127 0.1499 0.1502
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Echinococcus granulosus hypothetical protein 0.0012 0.0026 0.0009
Schistosoma mansoni amidase 0.0098 0.1129 0.1786
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Echinococcus granulosus nuclear receptor nhr 48 0.0049 0.0497 0.076
Brugia malayi Integrin alpha pat-2 precursor 0.0149 0.178 0.1799
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Brugia malayi Peptidase family M13 containing protein 0.0192 0.2322 0.2348
Loa Loa (eye worm) hypothetical protein 0.0095 0.1084 0.1093
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0133 0.0129
Brugia malayi Cathepsin L-like precursor 0.0033 0.0285 0.0283
Leishmania major hypothetical protein, conserved 0.0012 0.0026 0.0006
Mycobacterium tuberculosis Possible oxidoreductase 0.0012 0.0026 0.0007
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0095 0.012
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0019 0.0108 0.014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0012 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0044
Brugia malayi Protein kinase domain containing protein 0.002 0.0124 0.012
Onchocerca volvulus 0.0019 0.0108 0.0095
Brugia malayi hypothetical protein 0.0018 0.0095 0.0091
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Brugia malayi Dehydrogenases, short chain protein 30 0.0012 0.0026 0.002
Brugia malayi p70 ribosomal S6 kinase beta 0.002 0.0124 0.012
Onchocerca volvulus 0.0018 0.0095 0.0081
Brugia malayi putative neuropeptide receptor 0.0018 0.0095 0.0091
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0133 0.0229
Loa Loa (eye worm) nuclear hormone receptor 0.0049 0.0497 0.0498
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0006
Brugia malayi Protein kinase domain containing protein 0.0014 0.0051 0.0046
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0017 0.0083 0.0064
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0108 0.0103
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0063 0.0043
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0285 0.0264
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0019 0.0108 0.0103
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0097 0.1106 0.1749
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0029 0.0238 0.0235
Brugia malayi hypothetical protein 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.0166 0.0162
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.03 0.3714 0.376
Trichomonas vaginalis AGC family protein kinase 0.002 0.0124 0.0099
Plasmodium vivax aspartyl proteinase, putative 0.0122 0.1432 0.3042
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0095 0.0075
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0437 0.0685
Brugia malayi Hr1 repeat family protein 0.002 0.0124 0.012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0108 0.0103
Loa Loa (eye worm) oxidoreductase 0.0012 0.0026 0.002
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0095 0.012
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0012 0.0026 0.0006
Brugia malayi hypothetical protein 0.0029 0.0238 0.0235
Schistosoma mansoni zinc finger protein 0.0026 0.0206 0.0319
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0049 0.0497 0.0498
Brugia malayi protein kinase C II. 0.0037 0.0342 0.0341
Echinococcus multilocularis serine:threonine protein kinase N2 0.002 0.0124 0.0104
Loa Loa (eye worm) hypothetical protein 0.0048 0.0485 0.0486
Loa Loa (eye worm) hypothetical protein 0.0122 0.1432 0.1446
Mycobacterium ulcerans hypothetical protein 0.0105 0.1209 0.1207
Echinococcus granulosus flap endonuclease 1 0.0025 0.019 0.0271
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0259 0.0239
Mycobacterium tuberculosis Probable lipase LipE 0.0105 0.1209 0.1413
Echinococcus granulosus snurportin 1 0.03 0.3714 0.5886
Loa Loa (eye worm) hypothetical protein 0.0023 0.0166 0.0162
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.0378 0.4707 0.7468
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0045 0.0447 0.0428
Toxoplasma gondii methionine aminopeptidase 2, putative 0.0045 0.0447 0.0453
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0014 0.0049 0.0044
Echinococcus multilocularis protein kinase c epsilon type 0.0037 0.0342 0.0323
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0026 0.002
Echinococcus multilocularis nAChR subunit 0.0019 0.0108 0.0088
Trichomonas vaginalis AGC family protein kinase 0.002 0.0124 0.0099
Brugia malayi Cathepsin L-like precursor 0.0033 0.0285 0.0283
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0047 0.0466 0.0731
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0049 0.0497 0.0478
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0018 0.0095 0.0091
Onchocerca volvulus Putative nachr subunit 0.0019 0.0108 0.0095
Echinococcus granulosus histone lysine methyltransferase setb 0.0046 0.0455 0.0693
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0019 0.0108 0.0103
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0026 0.0006
Toxoplasma gondii aspartyl protease ASP3 0.0029 0.0238 0.0241
Brugia malayi Carboxylesterase family protein 0.0138 0.163 0.1646
Trypanosoma brucei ISWI complex protein 0.0015 0.0063 0.0044
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0049 0.0497 0.0478
Entamoeba histolytica cysteine protease, putative 0.0017 0.0083 0.0058
Entamoeba histolytica acetyltransferase, GNAT family 0.0076 0.084 0.0827
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0046 0.0063
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0138 0.163 0.1646
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0026 0.002
Leishmania major sterol 24-c-methyltransferase, putative 0.0212 0.2584 0.2603
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Echinococcus granulosus protein farnesyltransferase subunit beta 0.002 0.0126 0.017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.002
Trichomonas vaginalis AGC family protein kinase 0.002 0.0124 0.0099
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0026 0.0006
Brugia malayi hypothetical protein 0.0018 0.0095 0.0091
Brugia malayi Pepsin A precursor 0.0029 0.0238 0.0235
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0133 0.018
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0026 0.0009
Loa Loa (eye worm) hypothetical protein 0.0023 0.0166 0.0162
Onchocerca volvulus 0.0018 0.0095 0.0081
Trichomonas vaginalis hypothetical protein 0.0033 0.0284 0.0263
Trypanosoma cruzi cysteine peptidase, putative 0.0124 0.1458 0.1473
Entamoeba histolytica Flap nuclease, putative 0.0025 0.019 0.0167
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0018 0.0095 0.0142
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0285 0.0264
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.002 0.0126 0.0102
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0026 0.0032
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0014 0.0049 0.0044
Entamoeba histolytica cysteine proteinase 2 0.0017 0.0083 0.0058
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0097 0.1106 0.1749
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0779 0.0761
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0012 0.0026 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0017 0.0083 0.0064
Brugia malayi nuclear receptor RXR 0.0055 0.0572 0.0574
Schistosoma mansoni ran 0.0021 0.0133 0.0202
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0095 0.0075
Mycobacterium tuberculosis Probable oxidoreductase 0.0012 0.0026 0.0007
Loa Loa (eye worm) dehydrogenase 0.0012 0.0026 0.002
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0012 0.0026 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0124 0.0187
Loa Loa (eye worm) hypothetical protein 0.0098 0.1129 0.1139
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0026 0.0009
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0012 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0105 0.1209 0.122
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0095 0.0091
Toxoplasma gondii AGC kinase 0.002 0.0124 0.0125
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0045 0.0447 0.0428
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.002 0.0126 0.0102
Loa Loa (eye worm) zinc metallopeptidase 4 0.0047 0.0466 0.0466
Brugia malayi RhoGAP domain containing protein 0.0014 0.0049 0.0044
Brugia malayi Amidase family protein 0.0012 0.002 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0104 0.1201 0.1212
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0095 0.012
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0095 0.0091
Mycobacterium ulcerans carboxylesterase, LipT 0.0023 0.0166 0.0148
Loa Loa (eye worm) peptidase family M13 containing protein 0.0142 0.1682 0.1699
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0083 0.0058
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0048 0.0483 0.0484
Plasmodium falciparum flap endonuclease 1 0.0025 0.019 0.0363
Loa Loa (eye worm) AGC/NDR protein kinase 0.002 0.0124 0.012
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0095 0.012
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0019 0.0108 0.0103
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.002
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0083 0.0078
Loa Loa (eye worm) hypothetical protein 0.0192 0.2322 0.2348
Onchocerca volvulus 0.0033 0.0285 0.0301
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0105 0.1209 0.1913
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0656 0.0659
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0044
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0095 0.012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Brugia malayi amidase 0.0098 0.1129 0.1139
Mycobacterium tuberculosis Probable hydrolase 0.0105 0.1209 0.1413
Schistosoma mansoni nuclear receptor 0.0049 0.0497 0.078
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Brugia malayi Dopamine receptor protein 1 0.0018 0.0095 0.0091
Brugia malayi putative neuropeptide receptor NPR1 0.0018 0.0095 0.0091
Entamoeba histolytica hypothetical protein 0.0023 0.016 0.0136
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0095 0.0075
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.002
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0072 0.0784 0.0776
Brugia malayi kinase, mitochondrial precursor 0.0116 0.1356 0.1369
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0026 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0047 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0095 0.0142
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0656 0.1033
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0012 0.0026 0.002
Brugia malayi GnHR receptor homolog 0.0018 0.0095 0.0091
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0026 0.0009
Echinococcus granulosus aspartyl aminopeptidase 0.0069 0.0756 0.1173
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0212 0.2584 0.2603
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0378 0.4707 0.7473
Toxoplasma gondii peptidase family M13 protein 0.0192 0.2322 0.2353
Entamoeba histolytica Ran family GTPase 0.0021 0.0133 0.0109
Trypanosoma cruzi cysteine proteinase, putative 0.0017 0.0083 0.0078
Echinococcus multilocularis integrin alpha 3 0.0114 0.1334 0.1317
Echinococcus granulosus sex peptide receptor 0.0018 0.0095 0.012
Schistosoma mansoni steroid hormone receptor ad4bp 0.0104 0.1201 0.19
Echinococcus multilocularis g-protein coupled receptor 0.0018 0.0095 0.0075
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0108 0.0088
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0644 0.0633
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0095 0.0142
Loa Loa (eye worm) hypothetical protein 0.0104 0.1201 0.1212
Leishmania major methionine aminopeptidase 2, putative 0.0045 0.0447 0.0434
Echinococcus multilocularis acetylcholinesterase 0.0138 0.163 0.1613
Entamoeba histolytica hypothetical protein 0.0014 0.0049 0.0023
Brugia malayi nuclear hormone receptor family member nhr-6 0.0049 0.0497 0.0498
Brugia malayi sulfakinin receptor protein 0.0018 0.0095 0.0091
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0104 0.1201 0.1882
Schistosoma mansoni amine GPCR 0.0018 0.0095 0.0142
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0019 0.0108 0.014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0049 0.0497 0.0498
Schistosoma mansoni acetylcholinesterase 0.0023 0.0166 0.0254
Toxoplasma gondii ABC1 family protein 0.0105 0.1209 0.1225
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.002 0.0126 0.0269
Brugia malayi MH2 domain containing protein 0.0116 0.136 0.1372
Echinococcus multilocularis neuropeptide s receptor 0.0464 0.5817 0.5808
Toxoplasma gondii cathepsin CPL 0.0033 0.0285 0.0289
Echinococcus granulosus acetylcholinesterase 0.0138 0.163 0.2565
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0166 0.0173
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0095 0.0075
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Brugia malayi Nuclear hormone receptor E75 0.0049 0.0497 0.0498
Trichomonas vaginalis bromodomain-containing protein, putative 0.0085 0.0958 0.0947
Loa Loa (eye worm) hypothetical protein 0.0033 0.029 0.0288
Schistosoma mansoni amine GPCR 0.0018 0.0095 0.0142
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0104 0.1201 0.19
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0047 0.0466 0.0731
Loa Loa (eye worm) hypothetical protein 0.0014 0.0046 0.004
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0012 0.0026 0.002
Mycobacterium tuberculosis Probable dehydrogenase 0.0012 0.0026 0.0007
Brugia malayi Pre-SET motif family protein 0.0201 0.2444 0.2472
Loa Loa (eye worm) hypothetical protein 0.0023 0.0166 0.0162
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0656 0.1033
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0781 0.9869 1
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.136 0.1372
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0005
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0108 0.0103
Brugia malayi Cathepsin L-like precursor 0.0022 0.0147 0.0143
Schistosoma mansoni amine GPCR 0.0018 0.0095 0.0142
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0018 0.0095 0.0075
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0026 0.0032
Brugia malayi Cathepsin L-like precursor 0.0022 0.0147 0.0143
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0012 0.0026 0.0007
Trichomonas vaginalis D-aminoacylase, putative 0.0105 0.1209 0.1202
Schistosoma mansoni nAChR subunit 0.0019 0.0108 0.0162
Leishmania major quinonoid dihydropteridine reductase 0.0012 0.0026 0.0006
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0063 0.0058
Loa Loa (eye worm) hypothetical protein 0.0048 0.0477 0.0477
Schistosoma mansoni ran 0.0021 0.0133 0.0202
Onchocerca volvulus Methionine aminopeptidase 2 homolog 0.0045 0.0447 0.0489
Loa Loa (eye worm) hypothetical protein 0.0104 0.1201 0.1212
Echinococcus granulosus beta LACTamase domain containing family member 0.0105 0.1209 0.1894
Leishmania major cathepsin L-like protease 0.0033 0.0285 0.0269
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0019 0.0108 0.014
Echinococcus multilocularis serine:threonine protein kinase N2 0.002 0.0124 0.0104
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0104 0.1201 0.1183
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0124 0.0187
Trypanosoma cruzi ISWI complex protein 0.0015 0.0063 0.0058
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0285 0.0264
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Brugia malayi diacylglycerol kinase 0.0014 0.0049 0.0044
Trypanosoma cruzi cruzipain precursor, putative 0.0124 0.1458 0.1473
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0259 0.0257
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Brugia malayi PHD-finger family protein 0.0032 0.0275 0.0272
Loa Loa (eye worm) raf kinase 0.0014 0.0049 0.0044
Trypanosoma brucei short-chain dehydrogenase, putative 0.0012 0.0026 0.0006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0166 0.0254
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0201 0.2444 0.2472
Plasmodium falciparum plasmepsin I 0.0122 0.1432 0.3012
Echinococcus multilocularis methionyl aminopeptidase 2 0.0045 0.0447 0.0428
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0259 0.051
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.0026
Echinococcus granulosus neuropeptide s receptor 0.0464 0.5817 0.9237
Schistosoma mansoni nAChR subunit 0.0019 0.0108 0.0162
Loa Loa (eye worm) hypothetical protein 0.0019 0.0108 0.0103
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0259 0.0381
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0259 0.0402
Onchocerca volvulus 0.0019 0.0108 0.0095
Echinococcus granulosus unc 13 munc13 0.0017 0.0086 0.0106
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0049 0.0497 0.076
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0437 0.0685
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0083 0.0058
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0018 0.0095 0.0091
Brugia malayi TAR-binding protein 0.0061 0.0656 0.0659
Loa Loa (eye worm) amidase 0.0012 0.002 0.0014
Leishmania major farnesyltransferase beta subunit 0.002 0.0126 0.0108
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0108 0.0162
Loa Loa (eye worm) hypothetical protein 0.0145 0.1724 0.1742
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0018 0.0095 0.0142
Trypanosoma cruzi aspartyl aminopeptidase, putative 0.0069 0.0756 0.0761
Schistosoma mansoni hypothetical protein 0.0033 0.029 0.0451
Brugia malayi nuclear hormone receptor family member odr-7 0.0049 0.0497 0.0498
Leishmania major cathepsin L-like protease 0.0033 0.0285 0.0269
Trichomonas vaginalis AGC family protein kinase 0.002 0.0124 0.0099
Schistosoma mansoni neuropeptide receptor 0.0018 0.0095 0.0142
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0015 0.0054 0.0049
Plasmodium vivax plasmepsin V, putative 0.0029 0.0238 0.0505
Echinococcus multilocularis dro:myosuppressin receptor 0.0018 0.0095 0.0075
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0113 0.1315 0.1327
Schistosoma mansoni hypothetical protein 0.005 0.0508 0.0799
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0133 0.0129
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0095 0.0075
Entamoeba histolytica cysteine proteinase 1, putative 0.0017 0.0083 0.0058
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.002 0.0126 0.0122
Loa Loa (eye worm) hypothetical protein 0.0028 0.0228 0.0225
Onchocerca volvulus 0.0019 0.0108 0.0095
Echinococcus granulosus cathepsin L cysteine proteinase 0.0033 0.0285 0.0423
Loa Loa (eye worm) steroid hormone receptor 0.0104 0.1201 0.1212
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0104 0.1201 0.1363
Echinococcus multilocularis oxidoreductase 0.0012 0.0026 0.0006
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0259 0.0243
Schistosoma mansoni unc-13 (munc13) 0.0021 0.0134 0.0203
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0656 0.1033
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0644 0.1014
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0466 0.0731
Echinococcus granulosus cathepsin L cysteine protease 0.0017 0.0083 0.01
Onchocerca volvulus 0.0229 0.2801 0.3218
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0019 0.0108 0.0088
Brugia malayi Nuclear hormone receptor-like 1 0.0104 0.1201 0.1212
Brugia malayi Pleckstrin Homology Domain 0.0014 0.0049 0.0044
Entamoeba histolytica protein kinase, putative 0.002 0.0124 0.0099
Echinococcus multilocularis serotonin receptor 0.0018 0.0095 0.0075
Echinococcus granulosus G protein coupled receptor 139 0.0018 0.0095 0.012
Onchocerca volvulus 0.0378 0.4707 0.5428
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0285 0.0264
Echinococcus multilocularis cysteine protease 0.0033 0.0285 0.0266
Echinococcus granulosus hypothetical protein 0.0012 0.0026 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0085 0.0958 0.0971
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0259 0.0257
Toxoplasma gondii diacylglycerol kinase, putative 0.0014 0.0049 0.0049
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0055 0.0572 0.0574
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0072 0.0784 0.0789
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0126 0.0122
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0095 0.0075
Brugia malayi G protein-coupled receptor F59B2.13 0.0018 0.0095 0.0091
Echinococcus granulosus tumor protein p63 0.0328 0.407 0.6453
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0026 0.002
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0012 0.0026 0.0025
Schistosoma mansoni hypothetical protein 0.005 0.0508 0.0799
Schistosoma mansoni gliotactin 0.0023 0.0166 0.0254
Schistosoma mansoni protein kinase C mu 0.0015 0.0054 0.0077
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0284 0.3503 0.349
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0285 0.0264
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0012 0.0026 0.0009
Onchocerca volvulus 0.0023 0.0166 0.0162
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0012 0.0026 0.0006
Giardia lamblia Prenyltransferase 0.002 0.0126 0.0215
Schistosoma mansoni hypothetical protein 0.005 0.0508 0.0799
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0285 0.0264
Plasmodium falciparum plasmepsin II 0.0122 0.1432 0.3012
Schistosoma mansoni neuropeptide receptor 0.0018 0.0095 0.0142
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0045 0.0447 0.0428
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0095 0.0075
Echinococcus granulosus integrin alpha ps 0.0067 0.0725 0.1124
Schistosoma mansoni zinc finger protein 0.0049 0.0497 0.078
Brugia malayi Cathepsin L-like precursor 0.0033 0.0285 0.0283
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.002
Brugia malayi Carboxylesterase family protein 0.0023 0.0166 0.0162
Loa Loa (eye worm) hypothetical protein 0.0022 0.0147 0.0143
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0228 0.0211
Echinococcus multilocularis Ankyrin 0.0014 0.0047 0.0027
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.002
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0064 0.0688 0.2903
Mycobacterium ulcerans hypothetical protein 0.0781 0.9869 1
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0037 0.0342 0.0341
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0455 0.0714
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0012 0.0026 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1458 0.146
Loa Loa (eye worm) hypothetical protein 0.0015 0.0063 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0285 0.0264
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0045 0.0447 0.0448
Brugia malayi Carboxylesterase family protein 0.0138 0.163 0.1646
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Brugia malayi C1-like domain containing protein 0.0015 0.0054 0.0049
Onchocerca volvulus 0.0019 0.0108 0.0095
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.0719 0.1114
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0122 0.1432 0.1414
Echinococcus multilocularis synaptic glycoprotein sc2 0.0378 0.4707 0.4696
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.002 0.0126 0.0102
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.002 0.0126 0.0122
Loa Loa (eye worm) cysteine protease 0.0033 0.0285 0.0283
Brugia malayi Dehydrogenases, short chain protein 2 0.0012 0.0026 0.002
Brugia malayi RE15519p 0.0018 0.0095 0.0091
Echinococcus granulosus 7tm_1 domain containing protein 0.0018 0.0095 0.012
Mycobacterium tuberculosis Probable oxidoreductase 0.0012 0.0026 0.0007
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.019 0.0167
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0026 0.0009
Schistosoma mansoni zinc finger protein 0.0015 0.0063 0.0091
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0104 0.1201 0.1183
Brugia malayi steroid hormone receptor 0.0104 0.1201 0.1212
Brugia malayi Nuclear hormone receptor E75 0.0049 0.0497 0.0498
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.1458 0.146
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0483 0.0758
Schistosoma mansoni carbonyl reductase 0.0012 0.0026 0.0032
Loa Loa (eye worm) AGC/AKT protein kinase 0.002 0.0124 0.012
Plasmodium vivax polyprenol reductase, putative 0.0378 0.4707 1
Loa Loa (eye worm) carboxylesterase 0.0023 0.0166 0.0162
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0019 0.0108 0.0103
Schistosoma mansoni myosin xvIII 0.0018 0.0095 0.0142
Onchocerca volvulus Phospholipase A2 homolog 0.0686 0.865 1
Loa Loa (eye worm) hypothetical protein 0.0117 0.1369 0.1383
Onchocerca volvulus Neuropeptide F receptor homolog 0.0018 0.0095 0.0081
Echinococcus granulosus neuroligin 0.0023 0.0166 0.0232
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.0069 0.0756 0.0742
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0285 0.0264
Echinococcus multilocularis zinc finger protein 0.0026 0.0206 0.0187
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0026 0.0006
Onchocerca volvulus 0.0105 0.1209 0.1372
Onchocerca volvulus 0.0018 0.0095 0.0081
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0138 0.163 0.2581
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0012 0.0026 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.1209 0.122
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0104 0.1201 0.19
Onchocerca volvulus 0.0018 0.0095 0.0081
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0026 0.0006
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0046 0.004
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0104 0.1201 0.1212
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0095 0.0075
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.016 0.0136
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0018 0.0095 0.0142
Trichomonas vaginalis ran, putative 0.0021 0.0133 0.0109
Trypanosoma cruzi cysteine peptidase, putative 0.0124 0.1458 0.1473
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0133 0.0241
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0485 0.0486
Echinococcus granulosus peptide allatostatin:somatostatin 0.0018 0.0095 0.012
Brugia malayi hypothetical protein 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0116 0.1356 0.1369
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0095 0.012
Plasmodium vivax M18 aspartyl aminopeptidase, putative 0.0069 0.0756 0.1607
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0018 0.0095 0.0091
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0104 0.1201 0.1183
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0012 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0104 0.1201 0.1212
Loa Loa (eye worm) hypothetical protein 0.0049 0.0497 0.0498
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0095 0.012
Leishmania major GTP-binding protein, putative 0.0021 0.0133 0.0115
Loa Loa (eye worm) hypothetical protein 0.0105 0.1209 0.122
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0104 0.1201 0.1212
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0285 0.0264
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0108 0.0162
Loa Loa (eye worm) hypothetical protein 0.0781 0.9869 1
Schistosoma mansoni endothelin-converting enzyme-related 0.0047 0.0466 0.0731
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0656 0.0637
Schistosoma mansoni protein kinase C mu 0.0014 0.0049 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0285 0.0264
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0018 0.0095 0.0075
Leishmania major phospholipase A1, putative 0.0331 0.4104 0.4146
Mycobacterium leprae Probable oxidoreductase 0.0012 0.0026 0.0025
Mycobacterium ulcerans short-chain type oxidoreductase 0.0012 0.0026 0.0006
Echinococcus granulosus nAChR subunit 0.0019 0.0108 0.014
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0095 0.012
Echinococcus granulosus ecdysone induced protein 78C 0.0104 0.1201 0.1882
Giardia lamblia Synaptic glycoprotein SC2 0.0378 0.4707 1
Schistosoma mansoni diacylglycerol kinase theta 0.0014 0.0049 0.0068
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0133 0.0135
Entamoeba histolytica cysteine proteinase, putative 0.0022 0.0147 0.0123
Onchocerca volvulus 0.0014 0.0049 0.0027
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0026 0.0006
Schistosoma mansoni glutamyl-tRNA(Gln) amidotransferase subunit A 0.0012 0.002 0.0023
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0095 0.0075
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.0033 0.0284 0.0263
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0017 0.0083 0.0078
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0656 0.0659
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0054 0.0077
Onchocerca volvulus 0.0029 0.0238 0.0245
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0014 0.0049 0.0044
Brugia malayi Melatonin receptor type 1A 0.0018 0.0095 0.0091
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0497 0.076
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0105 0.1209 0.1413
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0104 0.1201 0.1212
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0378 0.4707 0.4769
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0259 0.0243
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0485 0.0486
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0007
Loa Loa (eye worm) hypothetical protein 0.0069 0.0756 0.0761
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0113 0.132 0.1333
Trichomonas vaginalis AGC family protein kinase 0.002 0.0124 0.0099
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0049 0.0497 0.078
Loa Loa (eye worm) hypothetical protein 0.0145 0.1724 0.1742
Trypanosoma brucei oxidoreductase-like protein 0.0012 0.0026 0.0006
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0072 0.0784 0.0795
Mycobacterium ulcerans beta-lactamase 0.0105 0.1209 0.1207
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Schistosoma mansoni hypothetical protein 0.0018 0.0095 0.0142
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0029 0.0238 0.0368
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.0781 0.9869 1
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0378 0.4707 0.4755
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0026 0.002
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0108 0.0103
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0095 0.0075
Trypanosoma cruzi amidase, putative 0.0012 0.002 0.0014
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0095 0.0142
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0012 0.0026 0.002
Trypanosoma cruzi cysteine protease, putative 0.0017 0.0083 0.0078
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0012 0.0026 0.0006
Echinococcus granulosus RNA directed DNA polymerase 0.0092 0.1048 0.1638
Toxoplasma gondii oxidoreductase, putative 0.0012 0.0026 0.0026
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0378 0.4707 0.4769
Schistosoma mansoni nuclear receptor nhr-48 0.0049 0.0497 0.078
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.002 0.0126 0.0102
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0644 0.0994
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0012 0.0026 0.0025
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0018 0.0095 0.0142
Leishmania major developmentally regulated phosphoprotein-like protein 0.0116 0.1356 0.1357
Loa Loa (eye worm) hypothetical protein 0.0018 0.0095 0.0091
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0104 0.1201 0.1882
Loa Loa (eye worm) oxidoreductase 0.0012 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0049 0.0497 0.0498
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0122 0.1432 0.2267
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0026 0.0032
Onchocerca volvulus 0.0029 0.0237 0.0245
Schistosoma mansoni neuropeptide receptor 0.0018 0.0095 0.0142
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0779 0.121
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.002 0.0126 0.0108
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0049 0.0497 0.0478
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0033 0.0285 0.0264
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0012 0.0026 0.0006
Loa Loa (eye worm) hypothetical protein 0.0092 0.1048 0.1057
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0026 0.0032
Plasmodium vivax vivapain-2 0.0033 0.0285 0.0606
Echinococcus multilocularis beta LACTamase domain containing family member 0.0105 0.1209 0.1191
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0047 0.0066
Entamoeba histolytica cysteine protease, putative 0.0033 0.0285 0.0264
Loa Loa (eye worm) hypothetical protein 0.0105 0.1209 0.122
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0098 0.1129 0.1112
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0045 0.0447 0.0428
Entamoeba histolytica protein kinase, putative 0.002 0.0124 0.0099
Loa Loa (eye worm) hypothetical protein 0.013 0.1529 0.1544
Mycobacterium ulcerans oxidoreductase 0.0012 0.0026 0.0006
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0108 0.0088
Onchocerca volvulus 0.0018 0.0095 0.0081
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0018 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0012 0.0026 0.002
Echinococcus multilocularis histone acetyltransferase myst3 0.0012 0.0023 0.0003
Loa Loa (eye worm) hypothetical protein 0.0104 0.1201 0.1212
Plasmodium falciparum plasmepsin V 0.0029 0.0238 0.0464
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0026 0.0006
Schistosoma mansoni opsin-like receptor 0.0018 0.0095 0.0142
Brugia malayi Eukaryotic aspartyl protease family protein 0.0029 0.0238 0.0235
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0104 0.1201 0.1212
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0083 0.0058
Trypanosoma brucei lanosterol synthase 0.0148 0.1758 0.1764
Loa Loa (eye worm) bromodomain containing protein 0.0025 0.0182 0.0179
Schistosoma mansoni growth hormone secretagogue receptor 0.0018 0.0095 0.0142
Brugia malayi Protein kinase domain containing protein 0.0015 0.0054 0.0049
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0012 0.0026 0.0007
Onchocerca volvulus 0.0018 0.0095 0.0081
Brugia malayi Synaptic glycoprotein SC2 0.0378 0.4707 0.4766
Schistosoma mansoni hypothetical protein 0.0015 0.0063 0.0091
Entamoeba histolytica methionine aminopeptidase, putative 0.0045 0.0447 0.0428
Loa Loa (eye worm) hypothetical protein 0.0033 0.0285 0.0283
Schistosoma mansoni serine/threonine protein kinase 0.0129 0.1522 0.2411
Mycobacterium ulcerans dehydrogenase/reductase 0.0012 0.0026 0.0006
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.0069 0.0756 0.0742
Onchocerca volvulus 0.0014 0.0049 0.0027
Mycobacterium tuberculosis Possible oxidoreductase 0.0012 0.0026 0.0007
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0044
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0085 0.0958 0.0971
Echinococcus granulosus neuropeptide receptor 0.0018 0.0095 0.012
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0026 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0095 0.0075
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0019 0.0108 0.014
Entamoeba histolytica cysteine protease, putative 0.0017 0.0083 0.0058
Echinococcus multilocularis GPCR, family 2 0.0015 0.0063 0.0043
Echinococcus granulosus cathepsin l1 0.0033 0.0285 0.0423

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 8 The compound was evaluated for the delayed hypersensitivity skin reaction (DHSR) activity after subcutaneous administration; 8/1 ChEMBL. 6218302
Inhibition (functional) = 31 % Mouse active Arthus (MAA) reaction activity was determined for an ip dose of 150 mg/kg in mouse; 31-40% ChEMBL. 6218302
Inhibition (functional) = 31 % Mouse active Arthus (MAA) reaction activity was determined for an ip dose of 150 mg/kg in mouse; 31-40% ChEMBL. 6218302

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.