Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0154 | 0.0731 | 0.3643 |
Brugia malayi | jmjC domain containing protein | 0.0145 | 0.0668 | 0.14 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0077 | 0.0182 | 0.0182 |
Brugia malayi | Peptidase family M1 containing protein | 0.0077 | 0.0182 | 0.028 |
Onchocerca volvulus | 0.0116 | 0.0463 | 0.0784 | |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0077 | 0.0182 | 0.0182 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0077 | 0.0182 | 0.0182 |
Onchocerca volvulus | 0.0077 | 0.0182 | 0.0198 | |
Brugia malayi | Bromodomain containing protein | 0.012 | 0.0487 | 0.0984 |
Echinococcus granulosus | aminopeptidase N | 0.0077 | 0.0182 | 0.0182 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.145 | 1 | 1 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.0266 | 0.1531 | 0.1531 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0182 | 0.0122 |
Mycobacterium ulcerans | hypothetical protein | 0.0171 | 0.0855 | 0.2629 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0093 | 0.0293 | 0.5973 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0116 | 0.0463 | 0.0287 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0145 | 0.0669 | 0.0612 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0077 | 0.0182 | 0.0792 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0435 | 0.2743 | 1 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0088 | 0.0263 | 0.0263 |
Echinococcus granulosus | chromobox protein 1 | 0.0145 | 0.0669 | 0.0669 |
Echinococcus multilocularis | peregrin | 0.012 | 0.0487 | 0.0487 |
Leishmania major | developmentally regulated phosphoprotein-like protein | 0.0266 | 0.1531 | 0.7608 |
Plasmodium vivax | hypothetical protein, conserved | 0.012 | 0.0487 | 1 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.0266 | 0.1531 | 0.1374 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0231 | 0.1281 | 0.467 |
Schistosoma mansoni | jumonji domain containing protein | 0.0312 | 0.1859 | 0.1708 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.0251 | 0.1425 | 0.1266 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.012 | 0.0487 | 1 |
Brugia malayi | hypothetical protein | 0.0077 | 0.0182 | 0.028 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0435 | 0.2743 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0093 | 0.0293 | 0.0114 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0077 | 0.0182 | 0.0792 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0891 | 0.6002 | 1 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0077 | 0.0182 | 0.0792 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0093 | 0.0293 | 0.0293 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0088 | 0.0263 | 0.0467 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0079 | 0.0194 | 0.5 |
Schistosoma mansoni | lipoxygenase | 0.0137 | 0.061 | 0.0436 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0077 | 0.0182 | 0.0792 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0093 | 0.0293 | 0.0293 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.1099 | 0.1045 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0088 | 0.0263 | 0.0263 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0194 | 0.0134 |
Trypanosoma brucei | developmentally regulated phosphoprotein | 0.0266 | 0.1531 | 0.7608 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0325 | 0.1955 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0087 | 0.0257 | 0.0359 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0077 | 0.0182 | 0.0792 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0325 | 0.1955 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0219 | 0.016 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0079 | 0.0194 | 0.3906 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0293 | 0.0234 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0082 | 0.0219 | 0.0038 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0646 | 0.4249 | 0.4214 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0077 | 0.0182 | 0.0182 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0077 | 0.0182 | 0.0182 |
Schistosoma mansoni | glutaminase | 0.029 | 0.1709 | 0.1555 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0182 | 0.0122 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0213 | 0.0153 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0079 | 0.0194 | 0.0012 |
Brugia malayi | hypothetical protein | 0.0077 | 0.0178 | 0.0272 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0077 | 0.0182 | 0.0182 |
Trypanosoma brucei | pyruvate dehydrogenase (lipoamide) kinase, putative | 0.0093 | 0.0295 | 0.0639 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0087 | 0.0027 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0079 | 0.0194 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0891 | 0.6002 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0096 | 0.0315 | 0.0136 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0079 | 0.0194 | 0.0707 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0251 | 0.1428 | 0.1428 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0088 | 0.0263 | 0.0083 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0108 | 0.0401 | 0.8205 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0079 | 0.0194 | 0.0394 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0325 | 0.1955 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0097 | 0.0328 | 0.0328 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0087 | 0.0257 | 0.0354 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.012 | 0.0487 | 1 |
Brugia malayi | Peptidase family M1 containing protein | 0.0077 | 0.0182 | 0.028 |
Brugia malayi | hypothetical protein | 0.0077 | 0.0182 | 0.028 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.012 | 0.0487 | 0.0487 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0137 | 0.061 | 0.061 |
Loa Loa (eye worm) | hypothetical protein | 0.0266 | 0.1531 | 0.148 |
Brugia malayi | hypothetical protein | 0.0251 | 0.1428 | 0.3154 |
Onchocerca volvulus | 0.0082 | 0.0219 | 0.0276 | |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0154 | 0.0731 | 0.3096 |
Schistosoma mansoni | hypothetical protein | 0.0693 | 0.4588 | 0.4488 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0079 | 0.0194 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0153 | 0.0723 | 0.0666 |
Onchocerca volvulus | 0.0735 | 0.4887 | 1 | |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0077 | 0.0182 | 0.0792 |
Schistosoma mansoni | chromobox protein | 0.0145 | 0.0669 | 0.0496 |
Leishmania major | pyruvate dehydrogenase (lipoamide) kinase, putative | 0.0093 | 0.0295 | 0.0639 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0145 | 0.0668 | 0.0668 |
Onchocerca volvulus | 0.0077 | 0.0182 | 0.0198 | |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.145 | 1 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0089 | 0.0269 | 0.0269 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.0266 | 0.1531 | 0.1531 |
Mycobacterium ulcerans | glutaminase | 0.029 | 0.1709 | 0.5962 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0082 | 0.0219 | 0.0038 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0081 | 0.0213 | 0.0285 |
Plasmodium falciparum | phd finger protein, putative | 0.012 | 0.0487 | 1 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0077 | 0.0182 | 0.0122 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0219 | 0.016 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.012 | 0.0487 | 0.0311 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0077 | 0.0182 | 0.0182 |
Onchocerca volvulus | Alhambra homolog | 0.012 | 0.0487 | 0.0834 |
Echinococcus multilocularis | jun protein | 0.0097 | 0.0328 | 0.0328 |
Schistosoma mansoni | hypothetical protein | 0.012 | 0.0487 | 0.0311 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0137 | 0.061 | 0.061 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0097 | 0.0328 | 0.0328 |
Loa Loa (eye worm) | PHD-finger family protein | 0.012 | 0.0487 | 0.043 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0891 | 0.6002 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0093 | 0.0293 | 0.3652 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0251 | 0.1428 | 0.1428 |
Trichomonas vaginalis | glutaminase, putative | 0.029 | 0.1709 | 0.2796 |
Brugia malayi | glutaminase DH11.1 | 0.029 | 0.1709 | 0.38 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.1428 | 0.1376 |
Schistosoma mansoni | jun-related protein | 0.0079 | 0.0197 | 0.0016 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.0251 | 0.1425 | 0.1266 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0093 | 0.0293 | 0.0114 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0153 | 0.0723 | 0.1527 |
Brugia malayi | Cation transporter family protein | 0.0082 | 0.0219 | 0.0366 |
Trichomonas vaginalis | set domain proteins, putative | 0.0735 | 0.4887 | 0.813 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0891 | 0.6002 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0891 | 0.6002 | 1 |
Toxoplasma gondii | pyruvate dehydrogenase kinase, putative | 0.0093 | 0.0295 | 0.601 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0309 | 0.025 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0891 | 0.6002 | 1 |
Brugia malayi | chromobox protein homolog 3 | 0.0081 | 0.0213 | 0.0351 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.145 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0145 | 0.0669 | 0.105 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0392 | 0.2436 | 0.2436 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0145 | 0.0668 | 0.0668 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0325 | 0.1955 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0171 | 0.0855 | 0.3118 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0392 | 0.2436 | 0.2436 |
Echinococcus multilocularis | chromobox protein 1 | 0.0145 | 0.0669 | 0.0669 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0247 | 0.1399 | 0.1347 |
Schistosoma mansoni | hypothetical protein | 0.0693 | 0.4588 | 0.4488 |
Echinococcus granulosus | jun protein | 0.0097 | 0.0328 | 0.0328 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0077 | 0.0182 | 0.0182 |
Echinococcus multilocularis | chromobox protein 1 | 0.0145 | 0.0669 | 0.0669 |
Trypanosoma cruzi | developmentally regulated phosphoprotein, putative | 0.0266 | 0.1531 | 0.7798 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0145 | 0.0668 | 0.0495 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0077 | 0.0182 | 0.0182 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0723 | 0.0666 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0077 | 0.0182 | 0.3656 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0154 | 0.0731 | 0.3096 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0079 | 0.0194 | 0.0194 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0077 | 0.0182 | 0.0233 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0435 | 0.2743 | 1 |
Loa Loa (eye worm) | glutaminase 2 | 0.029 | 0.1709 | 0.1659 |
Trichomonas vaginalis | chromobox protein, putative | 0.0145 | 0.0669 | 0.105 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0093 | 0.0293 | 0.0293 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0079 | 0.0194 | 0.0047 |
Brugia malayi | kinase, mitochondrial precursor | 0.0266 | 0.1531 | 0.339 |
Onchocerca volvulus | 0.0082 | 0.0219 | 0.0276 | |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0079 | 0.0194 | 0.0394 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0487 | 0.043 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0077 | 0.0182 | 0.0182 |
Brugia malayi | Probable ClpP-like protease | 0.0079 | 0.0194 | 0.0308 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0077 | 0.0182 | 0.3656 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0891 | 0.6002 | 1 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0077 | 0.0182 | 0.0792 |
Onchocerca volvulus | 0.0077 | 0.0178 | 0.019 | |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0079 | 0.0194 | 0.0194 |
Echinococcus granulosus | Pyruvate dehydrogenase lipoamide kinase | 0.0266 | 0.1531 | 0.1531 |
Echinococcus granulosus | peregrin | 0.012 | 0.0487 | 0.0487 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0104 | 0.0377 | 0.073 |
Schistosoma mansoni | chromobox protein | 0.0145 | 0.0669 | 0.0496 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0077 | 0.0182 | 0.0182 |
Brugia malayi | Pre-SET motif family protein | 0.0093 | 0.0293 | 0.0537 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0263 | 0.0204 |
Echinococcus multilocularis | geminin | 0.0693 | 0.4588 | 0.4588 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0377 | 0.0319 |
Loa Loa (eye worm) | aminopeptidase N | 0.0077 | 0.0182 | 0.0122 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0891 | 0.6002 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0891 | 0.6002 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0891 | 0.6002 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0891 | 0.6002 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0077 | 0.0182 | 0.0233 |
Toxoplasma gondii | aminopeptidase N protein | 0.0077 | 0.0182 | 0.3656 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.012 | 0.0487 | 0.0487 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0079 | 0.0194 | 0.0047 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0077 | 0.0182 | 0.0792 |
Brugia malayi | Heterochromatin protein 1 | 0.0145 | 0.0669 | 0.1402 |
Brugia malayi | PHD-finger family protein | 0.012 | 0.0487 | 0.0984 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0145 | 0.0668 | 0.0495 |
Echinococcus granulosus | chromobox protein 1 | 0.0145 | 0.0669 | 0.0669 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0077 | 0.0182 | 0.0233 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0891 | 0.6002 | 1 |
Echinococcus granulosus | jumonji domain containing protein | 0.0167 | 0.0823 | 0.0823 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0077 | 0.0182 | 0.0182 |
Onchocerca volvulus | 0.0082 | 0.0219 | 0.0276 | |
Brugia malayi | hypothetical protein | 0.0666 | 0.4398 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0087 | 0.0257 | 0.0359 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0081 | 0.0213 | 0.0262 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0167 | 0.0823 | 0.0823 |
Brugia malayi | bZIP transcription factor family protein | 0.0097 | 0.0328 | 0.0617 |
Trypanosoma cruzi | pyruvate dehydrogenase (lipoamide) kinase, putative | 0.0093 | 0.0295 | 0.1381 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0093 | 0.0293 | 0.0114 |
Echinococcus granulosus | geminin | 0.0693 | 0.4588 | 0.4588 |
Loa Loa (eye worm) | glutaminase | 0.029 | 0.1709 | 0.1659 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0077 | 0.0182 | 0.0122 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0079 | 0.0194 | 0.3906 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0153 | 0.0723 | 0.1527 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0179 | 0.0119 |
Brugia malayi | TATA binding protein associated factor | 0.0077 | 0.0182 | 0.028 |
Brugia malayi | jmjC domain containing protein | 0.0392 | 0.2436 | 0.5476 |
Onchocerca volvulus | 0.0088 | 0.0263 | 0.0367 | |
Brugia malayi | Pre-SET motif family protein | 0.0646 | 0.4249 | 0.9657 |
Schistosoma mansoni | hypothetical protein | 0.0079 | 0.0197 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0182 | 0.0122 |
Onchocerca volvulus | 0.0077 | 0.0182 | 0.0198 | |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0145 | 0.0668 | 0.0611 |
Brugia malayi | Peptidase family M1 containing protein | 0.0077 | 0.0182 | 0.028 |
Schistosoma mansoni | hypothetical protein | 0.0104 | 0.0377 | 0.0199 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0081 | 0.0213 | 0.0285 |
Echinococcus multilocularis | aminopeptidase N | 0.0077 | 0.0182 | 0.0182 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Diuretic activity (functional) | = 3.49 | Diuretic activity in rats | ChEMBL. | 3735318 |
K+ excretion (ADMET) | = 0.9 | Potassium salt excretion in conscious rat at the dose of 0.3 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
K+ excretion (ADMET) | = 1.1 | Potassium salt excretion in conscious rat at the dose of 3.0 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
K+ excretion (ADMET) | = 1.2 | Potassium salt excretion in conscious rat at the dose of 1.0 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
K+ excretion (ADMET) | = 1.3 | Potassium salt excretion in conscious rat at the dose of 10 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
K+ excretion (ADMET) | = 1.7 | Potassium salt excretion in conscious rat at the dose of 30 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
K+ excretion (ADMET) | = 1.9 | Potassium salt excretion in conscious rat at the dose of 100 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
MABP change (functional) | = 2 mmHg | Blood pressure change in rats after oral administration of 50 mg/kg dose after 4 hours | ChEMBL. | 3735318 |
MABP change (functional) | = 2 mmHg | Blood pressure change in rats after oral administration of 50 mg/kg dose after 24 hours | ChEMBL. | 3735318 |
Na+ excretion (ADMET) | = 0.9 | Sodium salt excretion in conscious rat at the dose of 3.0 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
Na+ excretion (ADMET) | = 1.1 | Sodium salt excretion in conscious rat at the dose of 0.3 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
Na+ excretion (ADMET) | = 1.1 | Sodium salt excretion in conscious rat at the dose of 1.0 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
Na+ excretion (ADMET) | = 1.1 | Sodium salt excretion in conscious rat at the dose of 10 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
Na+ excretion (ADMET) | = 1.6 | Sodium salt excretion in conscious rat at the dose of 30 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
Na+ excretion (ADMET) | = 1.6 | Sodium salt excretion in conscious rat at the dose of 100 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
Urinary volume (ADMET) | = 0.8 | Compound was tested for urinary volume excretion in conscious rat at the dose of 3.0 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
Urinary volume (ADMET) | = 0.9 | Compound was tested for urinary volume excretion in conscious rat at the dose of 0.3 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
Urinary volume (ADMET) | = 0.9 | Compound was tested for urinary volume excretion in conscious rat at the dose of 1.0 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
Urinary volume (ADMET) | = 1.1 | Compound was tested for urinary volume excretion in conscious rat at the dose of 10 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
Urinary volume (ADMET) | = 1.6 | Compound was tested for urinary volume excretion in conscious rat at the dose of 30 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
Urinary volume (ADMET) | = 1.6 | Compound was tested for urinary volume excretion in conscious rat at the dose of 100 mg/kg expressed as urinary excretion in treated rats/urinary excretion in control rats | ChEMBL. | 3735318 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.