Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | muscleblind protein | 0.0138 | 0.492 | 0.492 |
Brugia malayi | Muscleblind-like protein | 0.0138 | 0.492 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0013 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0017 | 0.0246 | 0.0169 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0017 | 0.0246 | 0.0246 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0034 | 0.0905 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0042 | 0.1206 | 0.1206 |
Leishmania major | DNA polymerase eta, putative | 0.0028 | 0.0658 | 0.1361 |
Leishmania major | GTP-binding protein, putative | 0.0019 | 0.0311 | 0.0215 |
Echinococcus granulosus | orexin receptor type 2 | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | thyroid hormone receptor | 0.0125 | 0.4443 | 0.4443 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0034 | 0.0905 | 0.0905 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0013 | 0.0079 | 0.0079 |
Brugia malayi | mbt repeat family protein | 0.0042 | 0.1206 | 0.2329 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0138 | 0.492 | 0.492 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0019 | 0.0311 | 0.0311 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0013 | 0.0079 | 0.0079 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0026 | 0.0587 | 0.3431 |
Echinococcus granulosus | g-protein coupled receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | neuropeptide receptor | 0.0013 | 0.0079 | 0.0079 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0039 | 0.1114 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0039 | 0.1107 | 0.1107 |
Echinococcus multilocularis | fmrfamide receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | neuropeptide receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0125 | 0.4414 | 0.4414 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0095 | 0.3268 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | sex peptide receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0039 | 0.1114 | 0.1114 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0017 | 0.0246 | 0.0246 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0034 | 0.0905 | 0.8788 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0013 | 0.0079 | 0.0079 |
Plasmodium falciparum | importin beta, putative | 0.0025 | 0.0569 | 0.3808 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0013 | 0.0079 | 0.0079 |
Onchocerca volvulus | 0.0042 | 0.1206 | 1 | |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0116 | 0.4083 | 0.4083 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0023 | 0.0499 | 0.1413 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0026 | 0.0587 | 0.3431 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0125 | 0.4414 | 0.4414 |
Echinococcus granulosus | hypothetical protein | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0171 | 0.6213 | 0.6213 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | expressed protein | 0.0029 | 0.0723 | 0.0723 |
Echinococcus granulosus | neuropeptide s receptor | 0.0013 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0095 | 0.3268 | 0.3215 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0095 | 0.3268 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.492 | 0.488 |
Schistosoma mansoni | hypothetical protein | 0.0269 | 1 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.0039 | 0.1107 | 0.1107 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0125 | 0.4414 | 0.4414 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0013 | 0.0079 | 0.0079 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0039 | 0.1114 | 0.287 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0029 | 0.0696 | 0.48 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0042 | 0.1206 | 0.1206 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0134 | 0.4762 | 0.9673 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.492 | 0.488 |
Schistosoma mansoni | myosin xvIII | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | acetyltransferase | 0.0134 | 0.4762 | 0.4721 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0017 | 0.0246 | 0.0246 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0048 | 0.143 | 0.279 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0013 | 0.0079 | 0.0079 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0095 | 0.3268 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0125 | 0.4414 | 0.437 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0034 | 0.0905 | 0.218 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0095 | 0.3268 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0039 | 0.1107 | 0.1107 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0042 | 0.1206 | 0.1206 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0013 | 0.0079 | 0.0079 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0246 | 0.0628 |
Echinococcus granulosus | somatostatin receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | amine GPCR | 0.0013 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1206 | 0.1137 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0025 | 0.0569 | 0.1628 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0095 | 0.3268 | 0.3268 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0023 | 0.0499 | 0.2344 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | neuropeptide receptor | 0.0013 | 0.0079 | 0.0079 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0246 | 0.0628 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0134 | 0.4762 | 0.4762 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0029 | 0.0696 | 0.1489 |
Echinococcus multilocularis | muscleblind protein | 0.0138 | 0.492 | 0.492 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0023 | 0.0499 | 0.0837 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0095 | 0.3268 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0013 | 0.0079 | 0.0079 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0246 | 0.0628 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0079 | 0.0079 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0095 | 0.3268 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0013 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0569 | 0.0494 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0017 | 0.0246 | 0.0628 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0039 | 0.1114 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0095 | 0.3268 | 1 |
Schistosoma mansoni | amine GPCR | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | allatostatin A receptor | 0.0013 | 0.0079 | 0.0079 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0026 | 0.0587 | 0.1126 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0026 | 0.0587 | 0.5 |
Schistosoma mansoni | histamine h1 receptor | 0.0013 | 0.0079 | 0.0079 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0034 | 0.0905 | 0.218 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0023 | 0.0499 | 0.2783 |
Echinococcus granulosus | sex peptide receptor | 0.0013 | 0.0079 | 0.0079 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0026 | 0.0587 | 0.1126 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | g protein coupled receptor | 0.0013 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1107 | 0.1037 |
Schistosoma mansoni | amine GPCR | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | g protein coupled receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | somatostatin receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0125 | 0.4414 | 0.4414 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0499 | 0.0424 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.013 | 0.4617 | 0.4617 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0034 | 0.0905 | 0.0905 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | ap endonuclease | 0.0034 | 0.0905 | 0.0905 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0036 | 0.0987 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0034 | 0.0905 | 0.7402 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0039 | 0.1114 | 0.287 |
Schistosoma mansoni | importin beta-1 | 0.0025 | 0.0569 | 0.0569 |
Trichomonas vaginalis | importin beta-1, putative | 0.002 | 0.0384 | 0.0457 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0013 | 0.0079 | 0.0079 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0019 | 0.0311 | 0.0481 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0019 | 0.0311 | 0.083 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0269 | 1 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0095 | 0.3268 | 0.3268 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0246 | 0.0628 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0029 | 0.0696 | 0.1489 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0039 | 0.1107 | 0.2125 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0042 | 0.1206 | 0.1137 |
Schistosoma mansoni | opsin-like receptor | 0.0013 | 0.0079 | 0.0079 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0034 | 0.0905 | 0.218 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0034 | 0.0905 | 0.218 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0095 | 0.3268 | 0.3268 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Leishmania major | DNA polymerase eta, putative | 0.0039 | 0.1107 | 0.2849 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Leishmania major | importin beta-1 subunit, putative | 0.002 | 0.0384 | 0.0457 |
Schistosoma mansoni | biogenic amine receptor | 0.0013 | 0.0079 | 0.0079 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0042 | 0.1206 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Brugia malayi | Importin beta-1 subunit | 0.0025 | 0.0569 | 0.1012 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0026 | 0.0587 | 0.3431 |
Echinococcus granulosus | neuropeptide receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | amine GPCR | 0.0013 | 0.0079 | 0.0079 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0095 | 0.3268 | 1 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0013 | 0.0079 | 0.0079 |
Trichomonas vaginalis | rotamase, putative | 0.0029 | 0.0696 | 0.1489 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0025 | 0.0569 | 0.3207 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0029 | 0.0723 | 0.065 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | biogenic amine receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0116 | 0.4083 | 0.4083 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0026 | 0.0587 | 0.3431 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0246 | 0.0628 |
Schistosoma mansoni | neuropeptide receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | hypothetical protein | 0.0261 | 0.9661 | 0.9661 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0171 | 0.6213 | 0.6213 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | fmrfamide receptor | 0.0013 | 0.0079 | 0.0079 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0036 | 0.0987 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0029 | 0.0696 | 0.1489 |
Toxoplasma gondii | exonuclease III APE | 0.0034 | 0.0905 | 0.7402 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0017 | 0.0246 | 0.0628 |
Schistosoma mansoni | opsin-like receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0042 | 0.1206 | 0.1206 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | g protein coupled receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0013 | 0.0079 | 0.0079 |
Brugia malayi | hypothetical protein | 0.0015 | 0.0178 | 0.0206 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0048 | 0.143 | 0.143 |
Echinococcus granulosus | allatostatin A receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0025 | 0.0569 | 0.1628 |
Entamoeba histolytica | hypothetical protein | 0.002 | 0.0384 | 0.0457 |
Echinococcus multilocularis | g protein coupled receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | expressed protein | 0.0029 | 0.0723 | 0.0723 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0029 | 0.0696 | 0.2024 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0013 | 0.0079 | 0.0079 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0017 | 0.0246 | 0.0628 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0125 | 0.4414 | 0.8955 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0079 | 0.0079 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0026 | 0.0587 | 0.3431 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0013 | 0.0079 | 0.0079 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0026 | 0.0587 | 0.1126 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0048 | 0.143 | 0.143 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0034 | 0.0905 | 0.218 |
Schistosoma mansoni | ran | 0.0019 | 0.0311 | 0.0311 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0246 | 0.0628 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0013 | 0.0079 | 0.0079 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0023 | 0.0499 | 0.2783 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0013 | 0.0079 | 0.0079 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0246 | 0.0628 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0013 | 0.0079 | 0.0079 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0246 | 0.0628 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0013 | 0.0079 | 0.0079 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0095 | 0.3268 | 0.5 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0013 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0095 | 0.3268 | 0.3215 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0013 | 0.0079 | 0.0079 |
Plasmodium vivax | importin-beta 2, putative | 0.0025 | 0.0569 | 0.3207 |
Loa Loa (eye worm) | phosphofructokinase | 0.0095 | 0.3268 | 0.3215 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0013 | 0.0079 | 0.0079 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0026 | 0.0587 | 0.1126 |
Brugia malayi | 6-phosphofructokinase | 0.0095 | 0.3268 | 0.6588 |
Loa Loa (eye worm) | MBCTL1 | 0.0048 | 0.143 | 0.1362 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0013 | 0.0079 | 0.0079 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0026 | 0.0587 | 0.4074 |
Echinococcus multilocularis | serotonin receptor | 0.0013 | 0.0079 | 0.0079 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0029 | 0.0723 | 0.1331 |
Trichomonas vaginalis | rotamase, putative | 0.0029 | 0.0723 | 0.1577 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | importin subunit beta 1 | 0.0025 | 0.0569 | 0.0569 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.002 | 0.0384 | 0.0457 |
Echinococcus granulosus | serotonin receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0125 | 0.4414 | 0.4414 |
Brugia malayi | mbt repeat family protein | 0.0042 | 0.1206 | 0.2329 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0019 | 0.0311 | 0.0215 |
Brugia malayi | RNA, U transporter 1 | 0.0072 | 0.2366 | 0.4724 |
Schistosoma mansoni | thyroid hormone receptor | 0.0125 | 0.4443 | 0.4443 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0042 | 0.1206 | 0.1206 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0019 | 0.0311 | 0.0235 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Entamoeba histolytica | Ran family GTPase | 0.0019 | 0.0311 | 0.0215 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0023 | 0.0499 | 0.2344 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0095 | 0.3268 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0029 | 0.0696 | 0.1489 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0026 | 0.0587 | 0.1126 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0039 | 0.1114 | 1 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0025 | 0.0569 | 0.0569 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | serotonin receptor | 0.0013 | 0.0079 | 0.0079 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0034 | 0.0905 | 0.1707 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0499 | 0.0869 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | ran | 0.0019 | 0.0311 | 0.0311 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0246 | 0.0628 |
Leishmania major | hypothetical protein, conserved | 0.0023 | 0.0499 | 0.0837 |
Trichomonas vaginalis | ran, putative | 0.0019 | 0.0311 | 0.0215 |
Echinococcus granulosus | dna polymerase kappa | 0.0017 | 0.0246 | 0.0246 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | neuropeptide receptor | 0.0013 | 0.0079 | 0.0079 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0034 | 0.0905 | 0.1188 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0095 | 0.3268 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0116 | 0.4083 | 0.4083 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0013 | 0.0079 | 0.0079 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0039 | 0.1107 | 0.3298 |
Schistosoma mansoni | ap endonuclease | 0.0034 | 0.0905 | 0.0905 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0042 | 0.1206 | 0.1206 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0019 | 0.0311 | 0.0878 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0723 | 0.1577 |
Echinococcus multilocularis | snurportin 1 | 0.0269 | 1 | 1 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0028 | 0.0658 | 0.4315 |
Echinococcus multilocularis | fmrfamide receptor | 0.0013 | 0.0079 | 0.0079 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0095 | 0.3268 | 1 |
Brugia malayi | 6-phosphofructokinase | 0.0095 | 0.3268 | 0.6588 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0026 | 0.0587 | 0.1126 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0048 | 0.143 | 0.143 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0042 | 0.1206 | 0.1206 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.002 | 0.0384 | 0.0457 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.002 | 0.0384 | 0.0457 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0034 | 0.0905 | 0.2671 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0013 | 0.0079 | 0.0079 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0036 | 0.0987 | 0.2451 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0013 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0034 | 0.0905 | 0.0833 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0026 | 0.0587 | 0.1126 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0019 | 0.0311 | 0.0215 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0013 | 0.0079 | 0.0079 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0034 | 0.0905 | 0.218 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0048 | 0.143 | 0.143 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0034 | 0.0905 | 0.8895 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0019 | 0.0311 | 0.0311 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0013 | 0.0079 | 0.0079 |
Trypanosoma brucei | unspecified product | 0.0017 | 0.0246 | 0.0628 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0013 | 0.0079 | 0.0079 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0034 | 0.0905 | 0.218 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0095 | 0.3268 | 0.3268 |
Echinococcus multilocularis | g protein coupled receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | neuropeptide receptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | adenoreceptor | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | biogenic amine receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0125 | 0.4443 | 0.4443 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0026 | 0.0587 | 0.4594 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0013 | 0.0079 | 0.0079 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0017 | 0.0246 | 0.0346 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0134 | 0.4762 | 0.4762 |
Echinococcus multilocularis | dna polymerase kappa | 0.0017 | 0.0246 | 0.0246 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | amine GPCR | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0013 | 0.0079 | 0.0079 |
Schistosoma mansoni | rotamase | 0.0029 | 0.0723 | 0.0723 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0026 | 0.0587 | 0.5 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0017 | 0.0246 | 0.0246 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0039 | 0.1107 | 0.2849 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0028 | 0.0658 | 0.1361 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.143 | 0.1362 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0048 | 0.143 | 0.143 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0013 | 0.0079 | 0.0079 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0095 | 0.3268 | 1 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0125 | 0.4414 | 0.4414 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0246 | 0.0628 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0034 | 0.0905 | 0.218 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | g protein coupled receptor | 0.0013 | 0.0079 | 0.0079 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0026 | 0.0587 | 0.1126 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0013 | 0.0079 | 0.0079 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0125 | 0.4414 | 0.4414 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0013 | 0.0079 | 0.0079 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0023 | 0.0499 | 0.0837 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0095 | 0.3268 | 1 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0013 | 0.0079 | 0.0079 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0013 | 0.0079 | 0.0079 |
Brugia malayi | phosphofructokinase | 0.0095 | 0.3268 | 0.6588 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0013 | 0.0079 | 0.0079 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0026 | 0.0587 | 0.4074 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | <= 40 % | Inhibition of EphB4 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of ERBB2 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of FAK at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of IGF1R at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of SRC at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of VEGFR2 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of VEGFR3 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of AKT1 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of aurora A at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of aurora B at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of CDK4/cyclinA at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of CDK4/cyclinD1 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of CK2-alpha1 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of PLK1 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of TIE2 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of FLT3 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of MET at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of PDGFRbeta at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of ARK5 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of PAK4 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of PDK1 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of SAK at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of EphB4 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of ERBB2 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of FAK at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of IGF1R at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of SRC at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of VEGFR2 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of VEGFR3 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of AKT1 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of aurora A at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of aurora B at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of PLK1 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of TIE2 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of FLT3 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of MET at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of PDGFRbeta at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of ARK5 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of PAK4 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of PDK1 at 10 uM | ChEMBL. | 17448574 |
Inhibition (binding) | <= 40 % | Inhibition of SAK at 10 uM | ChEMBL. | 17448574 |
Inhibition (functional) | = 49 % | Antiproliferative activity against human NCI-H460 cells at 100 uM after 48 hrs relative to control | ChEMBL. | 17448574 |
Inhibition (functional) | = 49 % | Antiproliferative activity against human NCI-H460 cells at 100 uM after 48 hrs relative to control | ChEMBL. | 17448574 |
Inhibition (functional) | = 64 % | Antiproliferative activity against human MCF7 cells at 100 uM after 48 hrs relative to control | ChEMBL. | 17448574 |
Inhibition (functional) | = 64 % | Antiproliferative activity against human MCF7 cells at 100 uM after 48 hrs relative to control | ChEMBL. | 17448574 |
Inhibition (functional) | = 98 % | Antiproliferative activity against human SF268 cells at 100 uM after 48 hrs relative to control | ChEMBL. | 17448574 |
Inhibition (functional) | = 98 % | Antiproliferative activity against human SF268 cells at 100 uM after 48 hrs relative to control | ChEMBL. | 17448574 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.