Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | thymidylate synthase | 0.0105 | 0.0817 | 0.0817 |
Trypanosoma brucei | squalene monooxygenase, putative | 0.0164 | 0.1499 | 0.2592 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0068 | 0.0393 | 0.0679 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.004 | 0.0074 | 0.0128 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0411 | 0.4329 | 0.6691 |
Echinococcus granulosus | snurportin 1 | 0.036 | 0.3748 | 0.6481 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0074 | 0.0115 |
Brugia malayi | RNA, U transporter 1 | 0.0096 | 0.0714 | 0.111 |
Schistosoma mansoni | jumonji domain containing protein | 0.0131 | 0.1121 | 0.1938 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0131 | 0.1121 | 0.1743 |
Schistosoma mansoni | patched 1 | 0.0221 | 0.2153 | 0.3723 |
Plasmodium vivax | hypothetical protein, conserved | 0.004 | 0.0074 | 0.0564 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0148 | 0.1308 | 0.2242 |
Schistosoma mansoni | jumonji domain containing protein | 0.0035 | 0.0015 | 0.0026 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0041 | 0.0079 | 0.0606 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.039 | 0.4088 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0221 | 0.2153 | 0.3269 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0041 | 0.0079 | 0.0112 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0221 | 0.2153 | 0.2153 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0041 | 0.0079 | 0.0137 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0041 | 0.0079 | 0.0123 |
Brugia malayi | Probable ClpP-like protease | 0.0082 | 0.0555 | 0.0862 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0105 | 0.0817 | 0.2991 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.0235 | 0.0406 |
Loa Loa (eye worm) | hypothetical protein | 0.0538 | 0.5783 | 0.899 |
Brugia malayi | jmjC domain containing protein | 0.0035 | 0.0015 | 0.0023 |
Echinococcus granulosus | phd:f box containing protein | 0.0035 | 0.0015 | 0.0026 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0041 | 0.0079 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.2153 | 0.3347 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0035 | 0.0015 | 0.0026 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.004 | 0.0074 | 0.0115 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0035 | 0.0015 | 0.0114 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0594 | 0.6433 | 1 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0221 | 0.2153 | 0.3723 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0063 | 0.034 | 0.0529 |
Schistosoma mansoni | hypothetical protein | 0.0198 | 0.1889 | 0.3267 |
Leishmania major | squalene monooxygenase-like protein | 0.0164 | 0.1499 | 0.2573 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0221 | 0.2153 | 0.3347 |
Echinococcus multilocularis | geminin | 0.0198 | 0.1889 | 0.1889 |
Toxoplasma gondii | exonuclease III APE | 0.0041 | 0.0079 | 0.0606 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0041 | 0.0079 | 0.0123 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.0538 | 0.5783 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0054 | 0.0235 | 0.0365 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0131 | 0.1121 | 0.1938 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0538 | 0.5783 | 1 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0068 | 0.0393 | 0.0611 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.0235 | 0.0406 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0538 | 0.5783 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0594 | 0.6433 | 1 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0041 | 0.0079 | 0.0137 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.039 | 0.4088 | 0.6312 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0082 | 0.0555 | 0.4239 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.0538 | 0.5783 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0257 | 0.2559 | 1 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0148 | 0.1308 | 1 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0082 | 0.0555 | 0.0555 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.039 | 0.4088 | 0.6312 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0148 | 0.1308 | 1 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0068 | 0.0393 | 0.0655 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0043 | 0.0104 | 0.0104 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0041 | 0.0079 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0015 | 0.0023 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0054 | 0.0235 | 0.0365 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0054 | 0.023 | 0.0398 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.039 | 0.4088 | 0.6312 |
Echinococcus multilocularis | protein dispatched 1 | 0.0221 | 0.2153 | 0.2153 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0131 | 0.1121 | 0.1938 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0035 | 0.0015 | 0.0023 |
Brugia malayi | beta-lactamase | 0.004 | 0.0074 | 0.0115 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.039 | 0.4088 | 0.6312 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0186 | 0.0176 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0041 | 0.0079 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0015 | 0.0023 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0035 | 0.0015 | 0.0023 |
Schistosoma mansoni | hypothetical protein | 0.036 | 0.3748 | 0.6481 |
Brugia malayi | thymidylate synthase | 0.0105 | 0.0817 | 0.127 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0015 | 0.0023 |
Loa Loa (eye worm) | beta-lactamase | 0.004 | 0.0074 | 0.0115 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0041 | 0.0079 | 0.0022 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0035 | 0.0015 | 0.0015 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0072 | 0.0438 | 0.0758 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0072 | 0.0438 | 0.1467 |
Brugia malayi | jmjC domain containing protein | 0.0131 | 0.1121 | 0.1743 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0082 | 0.0555 | 1 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0035 | 0.0015 | 0.0015 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.004 | 0.0074 | 0.0128 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0054 | 0.0235 | 0.0406 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0054 | 0.023 | 0.0629 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0411 | 0.4329 | 0.6691 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0072 | 0.0438 | 0.0734 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.0538 | 0.5783 | 0.899 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0594 | 0.6433 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0594 | 0.6433 | 1 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0594 | 0.6433 | 1 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0035 | 0.0015 | 0.0026 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0035 | 0.0015 | 0.0026 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0082 | 0.0555 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0041 | 0.0079 | 0.0137 |
Loa Loa (eye worm) | thymidylate synthase | 0.0105 | 0.0817 | 0.127 |
Toxoplasma gondii | ABC1 family protein | 0.004 | 0.0074 | 0.0564 |
Onchocerca volvulus | 0.0105 | 0.0817 | 0.1852 | |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0131 | 0.1121 | 0.1121 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0072 | 0.0438 | 0.0758 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0074 | 0.0115 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0148 | 0.1308 | 0.2242 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0041 | 0.0079 | 0.0112 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0035 | 0.0015 | 0.0026 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0538 | 0.5783 | 1 |
Echinococcus granulosus | geminin | 0.0198 | 0.1889 | 0.3267 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0252 | 0.2507 | 0.3827 |
Trypanosoma cruzi | squalene monooxygenase, putative | 0.0164 | 0.1499 | 0.2573 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0555 | 0.0862 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.039 | 0.4088 | 0.6312 |
Brugia malayi | jmjC domain containing protein | 0.0035 | 0.0015 | 0.0023 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.0235 | 0.0406 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0035 | 0.0015 | 0.0114 |
Schistosoma mansoni | protein phosphatase 2C | 0.0035 | 0.0015 | 0.0026 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.0538 | 0.5783 | 1 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0148 | 0.1308 | 1 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.005 | 0.0186 | 0.0296 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0068 | 0.0393 | 0.0559 |
Mycobacterium tuberculosis | Hypothetical protein | 0.005 | 0.0186 | 0.045 |
Schistosoma mansoni | ap endonuclease | 0.0041 | 0.0079 | 0.0137 |
Schistosoma mansoni | phd/f-box containing protein | 0.0035 | 0.0015 | 0.0026 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0082 | 0.0555 | 1 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0054 | 0.023 | 0.0629 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0221 | 0.2153 | 0.3723 |
Brugia malayi | beta-lactamase family protein | 0.004 | 0.0074 | 0.0115 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0035 | 0.0015 | 0.0026 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0252 | 0.2507 | 0.3827 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0043 | 0.0104 | 0.0052 |
Echinococcus multilocularis | snurportin 1 | 0.036 | 0.3748 | 0.3748 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0043 | 0.0104 | 0.0403 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0041 | 0.0079 | 0.0008 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0054 | 0.023 | 0.023 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.039 | 0.4088 | 0.6312 |
Echinococcus granulosus | dihydrofolate reductase | 0.0043 | 0.0104 | 0.0179 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0131 | 0.1121 | 0.1938 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0105 | 0.0817 | 0.1413 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0074 | 0.0102 |
Brugia malayi | jmjC domain containing protein | 0.0035 | 0.0015 | 0.0023 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0072 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0074 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0074 | 0.0115 |
Leishmania major | hypothetical protein, conserved | 0.004 | 0.0074 | 0.0102 |
Echinococcus multilocularis | protein patched | 0.0221 | 0.2153 | 0.2153 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0148 | 0.1308 | 0.2262 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0035 | 0.0015 | 0.0026 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0054 | 0.023 | 0.2102 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0072 | 0.0438 | 0.0639 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0082 | 0.0555 | 0.0959 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0074 | 0.0115 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0594 | 0.6433 | 1 |
Mycobacterium ulcerans | thymidylate synthase | 0.0105 | 0.0817 | 0.1302 |
Trypanosoma brucei | hypothetical protein, conserved | 0.004 | 0.0074 | 0.0128 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.039 | 0.4088 | 0.6312 |
Brugia malayi | hypothetical protein | 0.005 | 0.0186 | 0.0289 |
Echinococcus granulosus | thymidylate synthase | 0.0105 | 0.0817 | 0.1413 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0082 | 0.0555 | 0.0959 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0072 | 0.0438 | 0.0639 |
Brugia malayi | CHE-14 protein | 0.0221 | 0.2153 | 0.3347 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0221 | 0.2153 | 0.3723 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0538 | 0.5783 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0131 | 0.1121 | 0.1743 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0074 | 0.0115 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.0538 | 0.5783 | 0.5783 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0131 | 0.1121 | 0.1938 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0041 | 0.0079 | 0.0606 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0594 | 0.6433 | 1 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0105 | 0.0817 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0131 | 0.1121 | 0.1121 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0035 | 0.0015 | 0.0026 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0054 | 0.0235 | 0.0406 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0252 | 0.2507 | 0.3827 |
Brugia malayi | Dihydrofolate reductase | 0.0043 | 0.0104 | 0.0161 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0054 | 0.0235 | 0.0235 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0221 | 0.2153 | 0.2153 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0072 | 0.0438 | 0.3351 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0041 | 0.0079 | 0.0079 |
Brugia malayi | dihydrofolate reductase family protein | 0.0043 | 0.0104 | 0.0161 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0072 | 0.0438 | 0.0639 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0082 | 0.0555 | 0.4239 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0074 | 0.0102 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0082 | 0.0555 | 0.0842 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0068 | 0.0393 | 0.1284 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0082 | 0.0555 | 0.0842 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0082 | 0.0555 | 0.6469 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0068 | 0.0393 | 0.0393 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0035 | 0.0015 | 0.0015 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0035 | 0.0015 | 0.0114 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.004 | 0.0074 | 0.0128 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0041 | 0.0079 | 0.0112 |
Plasmodium vivax | JmjC domain containing protein | 0.0035 | 0.0015 | 0.0114 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0035 | 0.0015 | 0.0015 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0252 | 0.2507 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0035 | 0.0015 | 0.0023 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0054 | 0.0235 | 0.0235 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0594 | 0.6433 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0068 | 0.0393 | 0.0559 |
Brugia malayi | beta-lactamase family protein | 0.004 | 0.0074 | 0.0115 |
Trypanosoma cruzi | squalene monooxygenase, putative | 0.0164 | 0.1499 | 0.2573 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.004 | 0.0074 | 0.0115 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.036 | 0.3748 | 0.5826 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0082 | 0.0555 | 0.4239 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0068 | 0.0393 | 0.0679 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0043 | 0.0104 | 0.0121 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0043 | 0.0104 | 0.0161 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0072 | 0.0438 | 0.0758 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.004 | 0.0074 | 0.0074 |
Echinococcus multilocularis | phd:f box containing protein | 0.0035 | 0.0015 | 0.0015 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0082 | 0.0555 | 0.4239 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0082 | 0.0555 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0035 | 0.0015 | 0.0023 |
Schistosoma mansoni | hypothetical protein | 0.0198 | 0.1889 | 0.3267 |
Schistosoma mansoni | dihydrofolate reductase | 0.0043 | 0.0104 | 0.0179 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0221 | 0.2153 | 0.3723 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 9.6 uM | Inhibitory concentration of the compound required to inhibit murine leukemia L1210 cells proliferation | ChEMBL. | 15139766 |
IC50 (functional) | = 9.6 uM | Antiproliferative activity against mouse L1210 cells | ChEMBL. | 17081759 |
IC50 (functional) | = 12.3 uM | Inhibitory concentration of the compound required to inhibit human T-lymphoblast Molt4 cells proliferation | ChEMBL. | 15139766 |
IC50 (functional) | = 12.3 uM | Antiproliferative activity against human Molt/4 cells | ChEMBL. | 17081759 |
IC50 (functional) | = 15.9 uM | Inhibitory concentration of the compound required to inhibit human T-lymphoblast CEM cells proliferation | ChEMBL. | 15139766 |
IC50 (functional) | = 15.9 uM | Antiproliferative activity against human CEM cells | ChEMBL. | 17081759 |
IC50 (functional) | = 42.5 uM | Inhibitory concentration of the compound required to inhibit murine mammary carcinoma FM3A cells proliferation | ChEMBL. | 15139766 |
IC50 (functional) | = 42.5 uM | Antiproliferative activity against mouse FM3A cells | ChEMBL. | 17081759 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.