Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0086 | 0.0545 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.005 | 0.0086 | 0.0944 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.005 | 0.0086 | 0.0944 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.005 | 0.0086 | 0.0545 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.0441 | 0.4819 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0071 | 0.0162 | 0.2606 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0071 | 0.0162 | 0.1783 |
Echinococcus multilocularis | jun protein | 0.0085 | 0.0214 | 0.3432 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.005 | 0.0086 | 0.1384 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0085 | 0.0214 | 0.3432 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0031 | 0.0018 | 0.0111 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.0162 | 0.1777 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0031 | 0.0018 | 0.0192 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.005 | 0.0086 | 0.0545 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0031 | 0.0018 | 0.0111 |
Schistosoma mansoni | ATP-citrate synthase | 0.0136 | 0.0403 | 0.4405 |
Trypanosoma cruzi | squalene synthase, putative | 0.0252 | 0.083 | 1 |
Echinococcus granulosus | fructose 16 bisphosphate aldolase | 0.0091 | 0.0239 | 0.5432 |
Brugia malayi | Cytochrome P450 family protein | 0.0048 | 0.008 | 0.0506 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.005 | 0.0086 | 0.0545 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0035 | 0.0031 | 0.0163 |
Plasmodium vivax | fructose 1,6-bisphosphate aldolase, putative | 0.0091 | 0.0239 | 1 |
Brugia malayi | glutaminase DH11.1 | 0.0275 | 0.0914 | 0.5772 |
Brugia malayi | hypothetical protein | 0.0159 | 0.0488 | 0.3083 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.005 | 0.0086 | 0.0545 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0457 | 0.1584 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0055 | 0.0464 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0192 | 0.1214 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0055 | 0.0464 |
Schistosoma mansoni | hypothetical protein | 0.0079 | 0.0192 | 0.2103 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.005 | 0.0086 | 0.1958 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0055 | 0.0464 |
Loa Loa (eye worm) | fructose-bisphosphate aldolase 1 | 0.0091 | 0.0239 | 0.1511 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.005 | 0.0086 | 0.0545 |
Brugia malayi | ecdysteroid receptor | 0.005 | 0.0086 | 0.0545 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0055 | 0.0023 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.0061 | 0.0955 |
Schistosoma mansoni | thyroid hormone receptor | 0.0196 | 0.0624 | 0.6819 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0055 | 0.0464 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.0061 | 0.0955 |
Schistosoma mansoni | fructose 16-bisphosphate aldolase | 0.0091 | 0.0239 | 0.2618 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0055 | 0.0464 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0035 | 0.0032 | 0.052 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.0091 | 0.0239 | 0.2729 |
Echinococcus multilocularis | fructose 1,6 bisphosphate aldolase | 0.0091 | 0.0239 | 0.3839 |
Echinococcus multilocularis | carbonic anhydrase | 0.0031 | 0.0018 | 0.0282 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0036 | 0.0398 |
Onchocerca volvulus | Bile acid receptor homolog | 0.005 | 0.0086 | 0.3367 |
Brugia malayi | polk-prov protein | 0.0031 | 0.0018 | 0.0116 |
Echinococcus granulosus | Squalene phytoene synthase | 0.0079 | 0.0192 | 0.4365 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0147 | 0.093 |
Schistosoma mansoni | glutaminase | 0.0275 | 0.0914 | 1 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0.0048 | 0.1367 |
Trypanosoma cruzi | squalene synthase, putative | 0.0252 | 0.083 | 1 |
Brugia malayi | steroid hormone receptor | 0.005 | 0.0086 | 0.0545 |
Leishmania major | squalene synthase, putative | 0.0252 | 0.083 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0146 | 0.0439 | 0.4806 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0036 | 0.0398 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.0162 | 0.1777 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0031 | 0.0018 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0086 | 0.0545 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0048 | 0.008 | 0.0506 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0146 | 0.0441 | 1 |
Echinococcus granulosus | single minded 2 | 0.0035 | 0.0032 | 0.0736 |
Brugia malayi | hypoxia-induced factor 1 | 0.0147 | 0.0443 | 0.2797 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0031 | 0.0018 | 0.0111 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.005 | 0.0086 | 0.0944 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0142 | 0.0424 | 0.9632 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0039 | 0.0048 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0036 | 0.0584 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0047 | 0.0078 | 0.085 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.005 | 0.0086 | 0.1958 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.0061 | 0.0067 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.005 | 0.0086 | 0.0545 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.005 | 0.0086 | 0.1384 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.005 | 0.0086 | 0.1958 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0031 | 0.0018 | 0.0192 |
Toxoplasma gondii | ATP-citrate lyase, putative | 0.0155 | 0.0473 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0036 | 0.0827 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0055 | 0.0464 |
Schistosoma mansoni | fructose 16-bisphosphate aldolase | 0.0091 | 0.0239 | 0.2618 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.005 | 0.0086 | 0.0545 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.005 | 0.0086 | 0.1384 |
Loa Loa (eye worm) | acetyltransferase | 0.0146 | 0.0439 | 0.2774 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.005 | 0.0086 | 0.0545 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0031 | 0.0018 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0086 | 0.0545 |
Toxoplasma gondii | fructose-1,6-bisphosphate aldolase | 0.0091 | 0.0239 | 0.4875 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.0488 | 0.3083 |
Echinococcus granulosus | carbonic anhydrase II | 0.0031 | 0.0018 | 0.0399 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0029 | 0.0312 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.005 | 0.0086 | 0.0545 |
Mycobacterium tuberculosis | 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) | 0.2747 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.005 | 0.0086 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0086 | 0.0545 |
Schistosoma mansoni | nuclear hormone receptor | 0.005 | 0.0086 | 0.0944 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.005 | 0.0086 | 0.1384 |
Brugia malayi | nuclear hormone receptor | 0.005 | 0.0086 | 0.0545 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0018 | 0.0009 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0055 | 0.0464 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.005 | 0.0086 | 0.0545 |
Leishmania major | fructose-1,6-bisphosphate aldolase | 0.0091 | 0.0239 | 0.2729 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0055 | 0.0464 |
Echinococcus granulosus | fructose 16 bisphosphate aldolase | 0.0091 | 0.0239 | 0.5432 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.005 | 0.0086 | 0.0545 |
Echinococcus multilocularis | dna polymerase kappa | 0.0041 | 0.0055 | 0.0886 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0146 | 0.0441 | 0.7067 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0055 | 0.0464 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0031 | 0.0018 | 0.0111 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.005 | 0.0086 | 0.0545 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.005 | 0.0086 | 0.1958 |
Leishmania major | hypothetical protein, conserved | 0.0079 | 0.0192 | 0.215 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0031 | 0.0018 | 0.0111 |
Trypanosoma cruzi | phytoene synthase, putative | 0.0079 | 0.0192 | 0.215 |
Echinococcus granulosus | jun protein | 0.0085 | 0.0214 | 0.4856 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0205 | 0.1297 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0031 | 0.0018 | 0.0192 |
Echinococcus multilocularis | FTZ F1 alpha | 0.005 | 0.0086 | 0.1384 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0086 | 0.0546 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.005 | 0.0086 | 0.0944 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.005 | 0.0086 | 0.0545 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.005 | 0.0086 | 0.0545 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0055 | 0.0464 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0036 | 0.023 |
Echinococcus granulosus | carbonic anhydrase | 0.0031 | 0.0018 | 0.0399 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.005 | 0.0086 | 0.0545 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0031 | 0.0018 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0086 | 0.0545 |
Trypanosoma brucei | fructose-bisphosphate aldolase, glycosomal, putative | 0.0091 | 0.0239 | 0.2729 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0031 | 0.0018 | 0.0111 |
Echinococcus multilocularis | fructose bisphosphate aldolase class I | 0.0091 | 0.0239 | 0.3839 |
Echinococcus multilocularis | carbonic anhydrase | 0.0031 | 0.0018 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0018 | 0.0111 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0086 | 0.0546 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0147 | 0.0443 | 0.2797 |
Echinococcus multilocularis | carbonic anhydrase | 0.0031 | 0.0018 | 0.0282 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0146 | 0.0439 | 0.7048 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.0061 | 0.1385 |
Loa Loa (eye worm) | glutaminase 2 | 0.0275 | 0.0914 | 0.5772 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0071 | 0.0162 | 0.3688 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0055 | 0.0464 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0031 | 0.0018 | 0.0192 |
Mycobacterium ulcerans | phytoene synthase, CrtB | 0.0079 | 0.0192 | 0.016 |
Brugia malayi | bZIP transcription factor family protein | 0.0085 | 0.0214 | 0.135 |
Echinococcus granulosus | fructose bisphosphate aldolase class I | 0.0091 | 0.0239 | 0.5432 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.005 | 0.0086 | 0.1958 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.005 | 0.0086 | 0.0545 |
Trypanosoma brucei | squalene synthase, putative | 0.0252 | 0.083 | 1 |
Brugia malayi | bHLH-PAS transcription factor | 0.0035 | 0.0032 | 0.0205 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0086 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0086 | 0.0545 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0156 | 0.1704 |
Brugia malayi | ATP-citrate synthase | 0.0155 | 0.0473 | 0.2983 |
Brugia malayi | PAS domain containing protein | 0.0047 | 0.0078 | 0.0491 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.005 | 0.0086 | 0.0944 |
Echinococcus multilocularis | fructose 1,6 bisphosphate aldolase | 0.0091 | 0.0239 | 0.3839 |
Echinococcus granulosus | FTZ F1 alpha | 0.005 | 0.0086 | 0.1958 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0031 | 0.0018 | 0.0282 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0018 | 0.0192 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0031 | 0.0018 | 0.0111 |
Mycobacterium ulcerans | 3-dehydroquinate dehydratase | 0.2747 | 1 | 1 |
Plasmodium falciparum | fructose-bisphosphate aldolase | 0.0091 | 0.0239 | 1 |
Mycobacterium ulcerans | glutaminase | 0.0275 | 0.0914 | 0.0885 |
Loa Loa (eye worm) | ATP-citrate synthase | 0.0155 | 0.0473 | 0.2983 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.0091 | 0.0239 | 0.2729 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0162 | 0.013 |
Brugia malayi | nuclear receptor NHR-88 | 0.005 | 0.0086 | 0.0545 |
Echinococcus granulosus | carbonic anhydrase | 0.0031 | 0.0018 | 0.0399 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0196 | 0.0624 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.0061 | 0.0067 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.005 | 0.0086 | 0.0944 |
Schistosoma mansoni | thyroid hormone receptor | 0.0196 | 0.0624 | 0.6819 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.005 | 0.0086 | 0.1958 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0055 | 0.0464 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.005 | 0.0086 | 0.3367 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0029 | 0.018 |
Echinococcus granulosus | dna polymerase kappa | 0.0041 | 0.0055 | 0.1254 |
Onchocerca volvulus | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog | 0.0079 | 0.0192 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.005 | 0.0086 | 0.0944 |
Echinococcus multilocularis | fructose 1,6 bisphosphate aldolase | 0.0091 | 0.0239 | 0.3839 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0055 | 0.0464 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.005 | 0.0086 | 0.0545 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0085 | 0.0214 | 0.4856 |
Schistosoma mansoni | single-minded | 0.0047 | 0.0078 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0086 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0018 | 0.0116 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.005 | 0.0086 | 0.1958 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0071 | 0.0162 | 0.3185 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.005 | 0.0086 | 0.3367 |
Onchocerca volvulus | 0.005 | 0.0086 | 0.3367 | |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.005 | 0.0086 | 0.0545 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0031 | 0.0018 | 0.0192 |
Loa Loa (eye worm) | steroid hormone receptor | 0.005 | 0.0086 | 0.0545 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0055 | 0.0464 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0055 | 0.0023 |
Loa Loa (eye worm) | fructose-bisphosphate aldolase 2 | 0.0091 | 0.0239 | 0.1511 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.0091 | 0.0239 | 0.2729 |
Trypanosoma brucei | unspecified product | 0.0035 | 0.0031 | 0.0163 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.005 | 0.0086 | 0.1384 |
Onchocerca volvulus | 0.0066 | 0.0147 | 0.7182 | |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.005 | 0.0086 | 0.0944 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0018 | 0.0111 |
Toxoplasma gondii | fructose-bisphosphate aldolase, putative | 0.0091 | 0.0239 | 0.4875 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.005 | 0.0086 | 0.1384 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0162 | 0.013 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.005 | 0.0086 | 0.0545 |
Toxoplasma gondii | fructose-1,6-bisphosphate aldolase | 0.0091 | 0.0239 | 0.4875 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0086 | 0.0545 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.005 | 0.0086 | 0.0545 |
Echinococcus granulosus | carbonic anhydrase | 0.0031 | 0.0018 | 0.0399 |
Brugia malayi | fructose-bisphosphate aldolase 2 | 0.0091 | 0.0239 | 0.1511 |
Brugia malayi | follicle stimulating hormone receptor | 0.0457 | 0.1584 | 1 |
Loa Loa (eye worm) | glutaminase | 0.0275 | 0.0914 | 0.5772 |
Schistosoma mansoni | carbonic anhydrase | 0.0031 | 0.0018 | 0.0192 |
Mycobacterium tuberculosis | Probable phytoene synthase PhyA | 0.0079 | 0.0192 | 0.003 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0018 | 0.0009 |
Echinococcus granulosus | fructose 16 bisphosphate aldolase | 0.0091 | 0.0239 | 0.5432 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.005 | 0.0086 | 0.1384 |
Brugia malayi | fructose-bisphosphate aldolase 1 | 0.0091 | 0.0239 | 0.1511 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0018 | 0.0111 |
Echinococcus multilocularis | Squalene phytoene synthase | 0.0079 | 0.0192 | 0.3084 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0162 | 0.013 |
Schistosoma mansoni | jun-related protein | 0.0069 | 0.0156 | 0.1704 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.005 | 0.0086 | 0.1958 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0039 | 0.0048 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.005 | 0.0086 | 0.0944 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0055 | 0.0464 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.0091 | 0.0239 | 0.2729 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0029 | 0.018 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0146 | 0.0439 | 0.2774 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.005 | 0.0086 | 0.0545 |
Schistosoma mansoni | coup transcription factor | 0.005 | 0.0086 | 0.0944 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.005 | 0.0086 | 0.0545 |
Trichomonas vaginalis | glutaminase, putative | 0.0275 | 0.0914 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0086 | 0.0546 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | > 20 uM | Antitumor activity against human BT20 cells by trypan blue exclusion assay | ChEMBL. | 18088089 |
IC50 (functional) | > 20 uM | Antitumor activity against AR-negative human DU145 cells by tryphan blue exclusion assay | ChEMBL. | 18088089 |
IC50 (functional) | > 20 uM | Antitumor activity against human H157 cells by tryphan blue exclusion assay | ChEMBL. | 18088089 |
IC50 (functional) | > 20 uM | Antitumor activity against human DLD1 cells by tryphan blue exclusion assay | ChEMBL. | 18088089 |
IC50 (functional) | > 20 uM | Antitumor activity against human BT20 cells by trypan blue exclusion assay | ChEMBL. | 18088089 |
IC50 (functional) | > 20 uM | Antitumor activity against AR-negative human DU145 cells by tryphan blue exclusion assay | ChEMBL. | 18088089 |
IC50 (functional) | > 20 uM | Antitumor activity against human DLD1 cells by tryphan blue exclusion assay | ChEMBL. | 18088089 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.