Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | lamin | 0.0028 | 0.3543 | 1 |
Echinococcus multilocularis | lamin | 0.0028 | 0.3543 | 1 |
Trichomonas vaginalis | histidinol-phosphate aminotransferase, putative | 0.0059 | 1 | 0.5 |
Onchocerca volvulus | 0.0028 | 0.3543 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0611 | 0.1725 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0912 | 0.2574 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.3543 | 1 |
Echinococcus multilocularis | musashi | 0.0028 | 0.3543 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.3543 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0507 | 0.1432 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.0912 | 0.2574 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.344 | 0.9707 |
Echinococcus granulosus | lamin | 0.0028 | 0.3543 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.3543 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.3543 | 1 |
Onchocerca volvulus | 0.0028 | 0.3543 | 1 | |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.3543 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.3543 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.3543 | 1 |
Trichomonas vaginalis | acc synthase, putative | 0.0059 | 1 | 0.5 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.3543 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.3543 | 1 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0611 | 0.1725 |
Schistosoma mansoni | lamin | 0.0028 | 0.3543 | 1 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0611 | 0.1725 |
Trichomonas vaginalis | histidinol-phosphate aminotransferase, putative | 0.0059 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0507 | 0.1432 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.