Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Echinococcus multilocularis | slit 2 protein | 0.0054 | 0.0884 | 0.0884 |
Entamoeba histolytica | hypothetical protein | 0.0145 | 0.3314 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.005 | 0.0779 | 0.0779 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0094 | 0.1957 | 0.1957 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0033 | 0.0339 | 0.0339 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0044 | 0.0637 | 0.0637 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0044 | 0.0637 | 0.0637 |
Brugia malayi | laminin alpha chain | 0.0054 | 0.0884 | 0.1462 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0103 | 0.2183 | 0.361 |
Brugia malayi | Pre-SET motif family protein | 0.0201 | 0.4788 | 0.7917 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Echinococcus granulosus | single minded 2 | 0.0035 | 0.0381 | 0.0381 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0044 | 0.0637 | 0.1113 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0223 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1957 | 0.3236 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.118 | 0.118 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.118 | 0.118 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0078 | 0.1524 | 0.1524 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1957 | 0.3236 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0094 | 0.1957 | 0.3236 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0094 | 0.1957 | 0.3417 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0044 | 0.0637 | 0.0637 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0044 | 0.0637 | 0.0637 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0094 | 0.1957 | 0.1957 |
Entamoeba histolytica | hypothetical protein | 0.0145 | 0.3314 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0149 | 0.0149 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.2007 | 0.3504 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0094 | 0.1957 | 0.1957 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0044 | 0.0637 | 0.1113 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0195 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0321 | 0.053 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.118 | 0.206 |
Schistosoma mansoni | hypothetical protein | 0.0145 | 0.3314 | 0.5785 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0044 | 0.0637 | 0.1054 |
Brugia malayi | PAS domain containing protein | 0.0047 | 0.0704 | 0.1165 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1957 | 0.3236 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0094 | 0.1957 | 0.3236 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0094 | 0.1957 | 0.3236 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0321 | 0.053 |
Brugia malayi | ecdysone receptor | 0.0044 | 0.0637 | 0.1054 |
Schistosoma mansoni | single-minded | 0.0047 | 0.0704 | 0.123 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0033 | 0.0339 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0094 | 0.1957 | 0.1957 |
Brugia malayi | nuclear hormone receptor | 0.0044 | 0.0637 | 0.1054 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0094 | 0.1957 | 0.3236 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0044 | 0.0637 | 0.1054 |
Schistosoma mansoni | chondroitin sulfate proteoglycan-related | 0.0054 | 0.0884 | 0.1543 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1957 | 0.3236 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.118 | 0.1952 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0044 | 0.0637 | 0.1054 |
Schistosoma mansoni | thyroid hormone receptor | 0.0094 | 0.1957 | 0.3417 |
Echinococcus multilocularis | expressed protein | 0.0398 | 1 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0033 | 0.0339 | 0.5 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0094 | 0.1957 | 0.3236 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.118 | 0.206 |
Echinococcus multilocularis | pikachurin | 0.0054 | 0.0884 | 0.0884 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0103 | 0.2183 | 0.361 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0094 | 0.1957 | 0.3417 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0094 | 0.1957 | 0.3364 |
Onchocerca volvulus | 0.0047 | 0.0694 | 0.1013 | |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0044 | 0.0637 | 0.0637 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0033 | 0.0339 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0094 | 0.1957 | 0.1957 |
Schistosoma mansoni | lamin | 0.0026 | 0.0149 | 0.026 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0094 | 0.1957 | 0.3417 |
Brugia malayi | steroid hormone receptor | 0.0094 | 0.1957 | 0.3236 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1957 | 0.3236 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0149 | 0.0149 |
Brugia malayi | hypothetical protein | 0.0145 | 0.3314 | 0.548 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0149 | 0.0247 |
Schistosoma mansoni | nuclear hormone receptor | 0.0044 | 0.0637 | 0.1113 |
Brugia malayi | nuclear receptor RXR | 0.005 | 0.0779 | 0.1288 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0094 | 0.1957 | 0.3236 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0044 | 0.0637 | 0.1054 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0149 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Brugia malayi | conserved hypotetical protein | 0.0044 | 0.0637 | 0.1054 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0044 | 0.0637 | 0.0637 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.005 | 0.0779 | 0.1359 |
Brugia malayi | Isocitrate dehydrogenase | 0.0033 | 0.0339 | 0.056 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0044 | 0.0637 | 0.1054 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0044 | 0.0637 | 0.0637 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0779 | 0.1288 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0094 | 0.1957 | 0.3236 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.118 | 0.1952 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0094 | 0.1957 | 0.3236 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0884 | 0.1462 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0054 | 0.0884 | 0.1543 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0054 | 0.0884 | 0.0884 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0779 | 0.1288 |
Entamoeba histolytica | hypothetical protein | 0.0145 | 0.3314 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0094 | 0.1957 | 0.3417 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0694 | 0.1211 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0094 | 0.1957 | 0.3236 |
Echinococcus granulosus | geminin | 0.0164 | 0.3797 | 0.3797 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0094 | 0.1957 | 0.1957 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Brugia malayi | laminin-like protein K08C7.3 precursor | 0.0054 | 0.0884 | 0.1462 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0094 | 0.1957 | 0.1957 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0103 | 0.2183 | 0.361 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0044 | 0.0637 | 0.0637 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0033 | 0.0339 | 0.5 |
Brugia malayi | Thrombospondin N-terminal -like domain containing protein | 0.0054 | 0.0884 | 0.1462 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.1321 | 0.2306 |
Schistosoma mansoni | gabp alpha | 0.0078 | 0.1524 | 0.266 |
Onchocerca volvulus | 0.0029 | 0.0223 | 0.0137 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0096 | 0.2007 | 0.2007 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0223 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1957 | 0.3236 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0321 | 0.056 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0094 | 0.1957 | 0.1957 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.005 | 0.0779 | 0.1288 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.0339 | 0.0339 |
Onchocerca volvulus | 0.0044 | 0.0637 | 0.0908 | |
Schistosoma mansoni | zinc finger protein | 0.0044 | 0.0637 | 0.1113 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.005 | 0.0779 | 0.0779 |
Brugia malayi | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0137 | 0.0226 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0044 | 0.0637 | 0.1054 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0044 | 0.0637 | 0.1113 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0033 | 0.0339 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0321 | 0.056 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0078 | 0.1524 | 0.1524 |
Brugia malayi | Ets-domain containing protein | 0.0078 | 0.1524 | 0.252 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0321 | 0.0321 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0145 | 0.3314 | 0.3314 |
Schistosoma mansoni | cell polarity protein | 0.0054 | 0.0884 | 0.1543 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0033 | 0.0339 | 0.0592 |
Schistosoma mansoni | slit | 0.0054 | 0.0884 | 0.1543 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0094 | 0.1957 | 0.3236 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0094 | 0.1957 | 0.3364 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0094 | 0.1957 | 0.3417 |
Schistosoma mansoni | lamin | 0.0026 | 0.0149 | 0.026 |
Brugia malayi | bHLH-PAS transcription factor | 0.0035 | 0.0381 | 0.0629 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0321 | 0.0321 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0044 | 0.0637 | 0.1054 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0033 | 0.0339 | 0.5 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0094 | 0.1957 | 0.3364 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0694 | 0.1147 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.005 | 0.0779 | 0.1288 |
Brugia malayi | Fli-1 protein | 0.0237 | 0.5728 | 0.9472 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0249 | 0.6047 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0321 | 0.056 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0094 | 0.1957 | 0.3236 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0321 | 0.0321 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1957 | 0.3236 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.1224 | 0.2024 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0044 | 0.0637 | 0.1054 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1321 | 0.2184 |
Brugia malayi | hypothetical protein | 0.005 | 0.0779 | 0.1288 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0149 | 0.0149 |
Echinococcus granulosus | pikachurin | 0.0054 | 0.0884 | 0.0884 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0145 | 0.3314 | 0.548 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0044 | 0.0637 | 0.0637 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0033 | 0.0339 | 0.0339 |
Echinococcus granulosus | slit 2 protein | 0.0054 | 0.0884 | 0.0884 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.118 | 0.1952 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.2183 | 0.361 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0078 | 0.1524 | 0.252 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0094 | 0.1957 | 0.1957 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0096 | 0.2007 | 0.3319 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.0339 | 0.0339 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0047 | 0.0704 | 0.123 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0094 | 0.1957 | 0.1957 |
Echinococcus granulosus | FTZ F1 alpha | 0.0094 | 0.1957 | 0.1957 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0694 | 0.1211 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0044 | 0.0637 | 0.0908 |
Brugia malayi | MH2 domain containing protein | 0.0249 | 0.6047 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0044 | 0.0637 | 0.0908 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.118 | 0.206 |
Brugia malayi | nuclear receptor RXR | 0.0044 | 0.0637 | 0.1054 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.2007 | 0.3504 |
Schistosoma mansoni | thyroid hormone receptor | 0.0094 | 0.1957 | 0.3417 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0094 | 0.1957 | 0.1957 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0223 | 0.0389 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0094 | 0.1957 | 0.1957 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0149 | 0.0247 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0094 | 0.1957 | 0.3236 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0094 | 0.1957 | 0.3236 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0149 | 0.0149 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0094 | 0.1957 | 0.1957 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0094 | 0.1957 | 0.3236 |
Brugia malayi | nuclear receptor NHR-88 | 0.0094 | 0.1957 | 0.3236 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0223 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0884 | 0.1462 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0094 | 0.1957 | 0.3236 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0321 | 0.0321 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0033 | 0.0339 | 0.056 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0321 | 0.053 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.3797 | 0.663 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.0339 | 0.0339 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.005 | 0.0779 | 0.1288 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.3797 | 0.663 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0094 | 0.1957 | 0.3236 |
Schistosoma mansoni | nuclear hormone receptor | 0.0044 | 0.0637 | 0.1113 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1957 | 0.3236 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0223 | 0.0223 |
Loa Loa (eye worm) | abnormal epIthelia family member | 0.0054 | 0.0884 | 0.1462 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0321 | 0.053 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0094 | 0.1957 | 0.3236 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0779 | 0.1288 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.118 | 0.206 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0223 | 0.0389 |
Brugia malayi | RNA binding protein | 0.0065 | 0.118 | 0.1952 |
Brugia malayi | isocitrate dehydrogenase | 0.0033 | 0.0339 | 0.056 |
Trichomonas vaginalis | set domain proteins, putative | 0.0229 | 0.5524 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.118 | 0.1952 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.005 | 0.0779 | 0.1359 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0223 | 0.0223 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0094 | 0.1957 | 0.3236 |
Brugia malayi | nuclear receptor NHR-88 | 0.0044 | 0.0637 | 0.1054 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0149 | 0.0247 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0223 | 0.0389 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0096 | 0.2007 | 0.2007 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0054 | 0.0884 | 0.0884 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0149 | 0.0247 |
Schistosoma mansoni | nuclear receptor | 0.0044 | 0.0637 | 0.1113 |
Brugia malayi | ecdysteroid receptor | 0.0094 | 0.1957 | 0.3236 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0779 | 0.1288 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0096 | 0.2007 | 0.2007 |
Brugia malayi | hypothetical protein | 0.005 | 0.0779 | 0.1288 |
Brugia malayi | nuclear receptor NHR-67 | 0.0044 | 0.0637 | 0.1054 |
Brugia malayi | tailless protein | 0.0044 | 0.0637 | 0.1054 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.0321 | 0.0321 |
Brugia malayi | hypothetical protein | 0.0228 | 0.5513 | 0.9118 |
Schistosoma mansoni | coup transcription factor | 0.0094 | 0.1957 | 0.3417 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0149 | 0.0247 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0044 | 0.0637 | 0.0637 |
Mycobacterium ulcerans | putative regulatory protein | 0.0035 | 0.0381 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.2007 | 0.3504 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0145 | 0.3314 | 0.5785 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0094 | 0.1957 | 0.1957 |
Onchocerca volvulus | 0.0035 | 0.0381 | 0.0431 | |
Onchocerca volvulus | 0.0094 | 0.1957 | 0.3364 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0094 | 0.1957 | 0.3236 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0094 | 0.1957 | 0.1957 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0228 | 0.5513 | 0.5513 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0094 | 0.1957 | 0.3236 |
Brugia malayi | hypoxia-induced factor 1 | 0.0145 | 0.3314 | 0.548 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0249 | 0.6047 | 1 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0035 | 0.0381 | 0.0381 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0094 | 0.1957 | 0.3236 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0094 | 0.1957 | 0.3417 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.1321 | 0.2184 |
Echinococcus multilocularis | geminin | 0.0164 | 0.3797 | 0.3797 |
Loa Loa (eye worm) | hypothetical protein | 0.0228 | 0.5513 | 0.9118 |
Echinococcus granulosus | lamin | 0.0026 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0201 | 0.4788 | 0.7917 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0223 | 0.0369 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0044 | 0.0637 | 0.0637 |
Loa Loa (eye worm) | fli-1 protein | 0.0237 | 0.5728 | 0.9472 |
Schistosoma mansoni | nuclear hormone receptor | 0.0094 | 0.1957 | 0.3417 |
Brugia malayi | Ets-domain containing protein | 0.0078 | 0.1524 | 0.252 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0096 | 0.2007 | 0.2007 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0094 | 0.1957 | 0.3417 |
Schistosoma mansoni | nuclear receptor | 0.0044 | 0.0637 | 0.1113 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0033 | 0.0339 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0094 | 0.1957 | 0.1957 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0884 | 0.1462 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0044 | 0.0637 | 0.0637 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0094 | 0.1957 | 0.3417 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0145 | 0.3314 | 0.3314 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0779 | 0.1288 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.118 | 0.206 |
Entamoeba histolytica | hypothetical protein | 0.0145 | 0.3314 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0033 | 0.0339 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0096 | 0.2007 | 0.3319 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.3638 | 0.6015 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0321 | 0.0321 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0044 | 0.0637 | 0.1054 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0094 | 0.1957 | 0.3236 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0033 | 0.0339 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0094 | 0.1957 | 0.1957 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0228 | 0.5513 | 0.5513 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0321 | 0.056 |
Brugia malayi | EGF-like domain containing protein | 0.0054 | 0.0884 | 0.1462 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0033 | 0.0339 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0094 | 0.1957 | 0.3236 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0094 | 0.1957 | 0.3236 |
Schistosoma mansoni | ets-related | 0.0237 | 0.5728 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0033 | 0.0339 | 0.0339 |
Onchocerca volvulus | 0.0229 | 0.5524 | 1 | |
Loa Loa (eye worm) | DR-78 | 0.0044 | 0.0637 | 0.1054 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0637 | 0.1054 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0094 | 0.1957 | 0.3417 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0094 | 0.1957 | 0.3236 |
Brugia malayi | hypothetical protein | 0.0158 | 0.3638 | 0.6015 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.118 | 0.1952 |
Onchocerca volvulus | 0.0044 | 0.0637 | 0.0908 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | > 50 uM | Cytotoxicity against mouse P388 cells after 72 hrs by MTT assay | ChEMBL. | 17896816 |
IC50 (functional) | > 50 uM | Cytotoxicity against human HL60 cells after 72 hrs by MTT assay | ChEMBL. | 17896816 |
IC50 (functional) | > 50 uM | Cytotoxicity against human BEL7402 cells after 24 hrs by SRB assay | ChEMBL. | 17896816 |
IC50 (functional) | > 50 uM | Cytotoxicity against human A459 cells after 24 hrs by SRB assay | ChEMBL. | 17896816 |
IC50 (functional) | > 50 uM | Cytotoxicity against mouse P388 cells after 72 hrs by MTT assay | ChEMBL. | 17896816 |
IC50 (functional) | > 50 uM | Cytotoxicity against human HL60 cells after 72 hrs by MTT assay | ChEMBL. | 17896816 |
IC50 (functional) | > 50 uM | Cytotoxicity against human BEL7402 cells after 24 hrs by SRB assay | ChEMBL. | 17896816 |
IC50 (functional) | = 97 uM | DPPH radical scavenging activity | ChEMBL. | 17896816 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.