Detailed information for compound 503890

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 459.577 | Formula: C29H33NO4
  • H donors: 2 H acceptors: 3 LogP: 3.38 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(O[C@H]1[C@@H]2C[C@@H]3C4([C@@H]1[C@@]15CCC[C@@]6([C@H]5[C@@](C4)(N(C31)C6)O)C)[C@@H](C2=C)O)/C=C/c1ccccc1
  • InChi: 1S/C29H33NO4/c1-16-18-13-19-23-27-12-6-11-26(2)15-30(23)29(33,25(26)27)14-28(19,24(16)32)22(27)21(18)34-20(31)10-9-17-7-4-3-5-8-17/h3-5,7-10,18-19,21-25,32-33H,1,6,11-15H2,2H3/b10-9+/t18-,19+,21+,22+,23?,24-,25-,26+,27+,28?,29+/m1/s1
  • InChiKey: RJZQOUOLLUXGKS-ORQGVBFASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus g protein coupled receptor 0.0136 0.1236 0.1236
Brugia malayi hypothetical protein 0.0245 0.2355 0.3858
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0052 0.0052
Plasmodium vivax SET domain protein, putative 0.0061 0.0472 0.0929
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2946 0.6238
Treponema pallidum thioredoxin reductase (trxB) 0.0073 0.0601 0.1899
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0032 0.0184 0.0378
Echinococcus multilocularis adenylate cyclase 9 0.0081 0.0677 0.0677
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0589 0.5866 0.7596
Echinococcus granulosus 7TM GPCR rhodopsin 0.0136 0.1236 0.1236
Entamoeba histolytica protein kinase, putative 0.0032 0.0181 0.0497
Echinococcus granulosus GPCR family 2 0.0033 0.0188 0.0188
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0036 0.0224 0.0243
Onchocerca volvulus 0.0073 0.0601 0.1149
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0073 0.0601 0.0764
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0066 0.0109
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0119 0.0176
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0036 0.0224 0.0224
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0036 0.0224 0.0367
Brugia malayi hypothetical protein 0.0136 0.1236 0.2024
Onchocerca volvulus 0.0021 0.0066 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0206 0.0427
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0032 0.0184 0.0378
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0036 0.0224 0.0367
Schistosoma mansoni tyrosine kinase 0.0051 0.0368 0.04
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0134 0.0273
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0243
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0276 0.2673 1
Loa Loa (eye worm) G-protein coupled receptor 0.0136 0.1236 0.2198
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0243
Brugia malayi hypothetical protein 0.0136 0.1236 0.2024
Brugia malayi AKH receptor 0.0136 0.1236 0.2024
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0036 0.0224 0.0368
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0136 0.1236 0.1236
Schistosoma mansoni amine GPCR 0.0136 0.1236 0.1343
Brugia malayi Receptor family ligand binding region containing protein 0.0024 0.0094 0.0154
Loa Loa (eye worm) solute carrier family 6 member 4 0.0251 0.2412 0.4291
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0136 0.1236 0.1343
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0116
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Trichomonas vaginalis glutamate synthase, putative 0.0073 0.0601 0.1264
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0149 0.0263
Mycobacterium ulcerans NADH dehydrogenase 0.0073 0.0601 0.2141
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0282 0.0282
Echinococcus multilocularis NMDA receptor 0.0072 0.0585 0.0585
Echinococcus multilocularis neuropeptides capa receptor 0.0136 0.1236 0.1236
Entamoeba histolytica thioredoxin reductase, putative 0.0073 0.0601 0.194
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0137 0.1252 0.1609
Schistosoma mansoni glutamate synthase 0.0073 0.0601 0.0653
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0012 0.002
Chlamydia trachomatis endonuclease IV 0.0079 0.0664 0.2191
Echinococcus granulosus somatostatin receptor 0.0136 0.1236 0.1236
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0243 0.0264
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0073 0.0601 0.0764
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0243 0.0243
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0066 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0066 0.0116
Brugia malayi Augmenter of liver regeneration 0.0036 0.0216 0.0353
Loa Loa (eye worm) hypothetical protein 0.0024 0.0094 0.0165
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0073 0.0601 0.0764
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0224 0.0224
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0043 0.0287 0.047
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0224 0.0224
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0095 0.0817 0.1045
Onchocerca volvulus Dual oxidase homolog 0.0075 0.0621 0.1193
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0066 0.0066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.1236 0.1343
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0472 0.0512
Loa Loa (eye worm) hypothetical protein 0.0098 0.0854 0.1518
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0406 0.0665
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0032 0.0184 0.0558
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Schistosoma mansoni voltage-gated ion channel 0.0036 0.0224 0.0243
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0134 0.1215 0.1215
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0136 0.1236 0.1236
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0224 0.0243
Echinococcus multilocularis sodium channel protein 0.0481 0.4764 0.4764
Loa Loa (eye worm) TYRA-2 protein 0.0136 0.1236 0.2198
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0066 0.0109
Echinococcus multilocularis two pore calcium channel protein 1 0.0036 0.0224 0.0224
Schistosoma mansoni lipoxygenase 0.018 0.1685 0.1831
Loa Loa (eye worm) hypothetical protein 0.0041 0.0276 0.0489
Chlamydia trachomatis thioredoxin reductase 0.0073 0.0601 0.1948
Toxoplasma gondii thioredoxin reductase 0.0477 0.4721 1
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0036 0.0224 0.0224
Schistosoma mansoni neuropeptide F-like receptor 0.0136 0.1236 0.1343
Brugia malayi ion channel NompC 0.0036 0.0224 0.0367
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0097
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0024 0.0094 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0066 0.0109
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.0026 0.0044
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0442 0.4366 0.7152
Brugia malayi Bromodomain containing protein 0.003 0.0161 0.0264
Loa Loa (eye worm) hypothetical protein 0.0024 0.0094 0.0165
Onchocerca volvulus 0.0136 0.1236 0.2513
Brugia malayi Adenylyl cyclase protein 0.0081 0.0677 0.1109
Brugia malayi isocitrate dehydrogenase 0.0033 0.0189 0.0309
Schistosoma mansoni 60S ribosomal protein L21 0.004 0.026 0.0282
Loa Loa (eye worm) hypothetical protein 0.0055 0.0411 0.073
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.01 0.0135
Schistosoma mansoni vesicular amine transporter 0.0036 0.0224 0.0243
Echinococcus granulosus TRP transient receptor potential channel 0.0036 0.0224 0.0224
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0041 0.0276 0.0276
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0073 0.0601 0.2141
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0073 0.0601 0.1264
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Schistosoma mansoni chromobox protein 0.0072 0.059 0.0641
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0012 0.0015
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0287 0.0534
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0073 0.0601 0.2141
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0104 0.0913 0.1624
Loa Loa (eye worm) hypothetical protein 0.0041 0.027 0.0478
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0073 0.0601 0.194
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0043 0.0287 0.0727
Loa Loa (eye worm) cytochrome P450 0.0032 0.0184 0.0325
Brugia malayi Serotonin receptor 0.0136 0.1236 0.2024
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0052 0.0032
Brugia malayi olfactory channel protein osm-9 0.0037 0.0227 0.0371
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0073 0.0601 0.2141
Leishmania major hypothetical protein, conserved 0.0026 0.0119 0.0139
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0073 0.0601 0.1264
Schistosoma mansoni amine GPCR 0.0136 0.1236 0.1343
Echinococcus multilocularis mitogen activated protein kinase 3 0.0102 0.0898 0.0898
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0066 0.0066
Treponema pallidum hypothetical protein 0.0029 0.0151 0.0342
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0243 0.03
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Schistosoma mansoni biogenic amine receptor 0.0136 0.1236 0.1343
Echinococcus granulosus neuropeptide Y receptor 0.0136 0.1236 0.1236
Loa Loa (eye worm) voltage-gated potassium channel 0.0036 0.0224 0.0397
Brugia malayi glutamate synthase 0.0073 0.0601 0.0985
Echinococcus granulosus RUN 0.0041 0.027 0.027
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0032 0.0184 0.0558
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0039 0.0253 0.0594
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0109 0.022
Onchocerca volvulus Calmodulin homolog 0.0025 0.0112 0.0098
Mycobacterium tuberculosis Probable dehydrogenase 0.0181 0.1697 0.3587
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.004 0.026 0.026
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0202 0.0369
Loa Loa (eye worm) hypothetical protein 0.0024 0.0094 0.0165
Brugia malayi hypothetical protein 0.0136 0.1236 0.2024
Mycobacterium ulcerans DNA gyrase subunit B 0.0085 0.0715 0.2574
Schistosoma mansoni lamin 0.0054 0.0406 0.0441
Echinococcus granulosus short transient receptor potential channel 6 0.0036 0.0224 0.0224
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0384 0.3768 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0109 0.022
Echinococcus granulosus voltage dependent calcium channel 0.0134 0.1215 0.1215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0012 0.0015
Schistosoma mansoni survival motor neuron protein 0.005 0.0363 0.0394
Schistosoma mansoni ATP-binding cassette transporter 0.0168 0.157 0.1706
Schistosoma mansoni biogenic amine (5HT) receptor 0.0388 0.3813 0.4144
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0051 0.0368 0.0368
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.027 0.027
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0024 0.0094 0.0094
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0066 0.0066
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0224 0.0224
Echinococcus multilocularis tyrosine protein kinase Srms 0.0036 0.0221 0.0221
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.0201 0.0201
Schistosoma mansoni hypothetical protein 0.003 0.0161 0.0175
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0032 0.0184 0.0558
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0771 0.772 1
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0073 0.0601 0.0601
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0442 0.4359 0.5639
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0181 0.1697 0.3587
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0134 0.1215 0.1215
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0024 0.0094 0.0094
Schistosoma mansoni opsin-like receptor 0.0136 0.1236 0.1343
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0073 0.0601 0.1205
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0276 0.2673 0.3452
Schistosoma mansoni hypothetical protein 0.0073 0.0601 0.0653
Trichomonas vaginalis glutamate synthase, putative 0.0073 0.0601 0.1264
Onchocerca volvulus 0.0136 0.1236 0.2513
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0136 0.1236 0.1236
Brugia malayi hypothetical protein 0.0136 0.1236 0.2024
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0041 0.0276 0.0276
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0036 0.0216 0.0264
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0032 0.0184 0.0378
Loa Loa (eye worm) hypothetical protein 0.0043 0.0287 0.0509
Echinococcus multilocularis calcium activated potassium channel 0.0037 0.0234 0.0234
Onchocerca volvulus 0.0043 0.0287 0.0475
Onchocerca volvulus 0.0136 0.1236 0.2513
Brugia malayi neuropeptide F receptor 0.0136 0.1236 0.2024
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0551 0.1769
Loa Loa (eye worm) hypothetical protein 0.0092 0.0794 0.1413
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0224 0.0224
Leishmania major calmodulin, putative 0.0025 0.0112 0.0129
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0243 0.0732
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0243
Schistosoma mansoni ap endonuclease 0.002 0.0052 0.0056
Echinococcus multilocularis epidermal growth factor receptor 0.0084 0.0712 0.0712
Onchocerca volvulus 0.0054 0.0406 0.073
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0066 0.0109
Schistosoma mansoni rab6-interacting 0.0041 0.027 0.0293
Echinococcus multilocularis somatostatin receptor 0.0136 0.1236 0.1236
Brugia malayi Inositol-1 0.0038 0.0243 0.0399
Echinococcus granulosus g-protein coupled receptor 0.0136 0.1236 0.1236
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0066 0.0072
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0036 0.0224 0.04
Echinococcus multilocularis glutamate receptor 2 0.0192 0.1808 0.1808
Echinococcus granulosus tm gpcr rhodopsin 0.0672 0.6713 0.6713
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0136 0.1236 0.1236
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Loa Loa (eye worm) hypothetical protein 0.0054 0.0406 0.0721
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0085 0.0717 0.1509
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0036 0.0224 0.0367
Schistosoma mansoni hypothetical protein 0.0033 0.0188 0.0204
Echinococcus granulosus glutamate receptor 2 0.0192 0.1808 0.1808
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0551 0.0699
Echinococcus granulosus tyrosine protein kinase Src42A 0.004 0.026 0.026
Brugia malayi Tachykinin-like peptides receptor 99D 0.0136 0.1236 0.2024
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0134 0.1215 0.1215
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Leishmania major hypothetical protein, conserved 0.0073 0.0601 0.0764
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0036 0.0224 0.0367
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Brugia malayi ORL1-like opioid receptor 0.0136 0.1236 0.2024
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0039 0.0253 0.0525
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0098 0.0852 0.1689
Echinococcus granulosus ryanodine receptor 44f 0.0036 0.0224 0.0224
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0032 0.0184 0.0558
Onchocerca volvulus 0.0043 0.0287 0.0475
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0066 0.0109
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0032 0.0184 0.0558
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0012 0.0013
Loa Loa (eye worm) blistered cuticle protein 3 0.0075 0.0621 0.1104
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0136 0.1236 0.2198
Schistosoma mansoni inositol monophosphatase 0.0038 0.0243 0.0264
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0066 0.0066
Brugia malayi hypothetical protein 0.0092 0.0794 0.1301
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0276 0.2673 0.4378
Mycobacterium ulcerans hypothetical protein 0.0073 0.0601 0.2141
Toxoplasma gondii hypothetical protein 0.0018 0.004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0073 0.0601 0.1068
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0662 0.6609 0.856
Echinococcus granulosus glutamate receptor NMDA 0.0082 0.0687 0.0687
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0036 0.0224 0.0224
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.1236 0.1343
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2586 0.5474
Echinococcus granulosus allatostatin A receptor 0.0136 0.1236 0.1236
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0073 0.0601 0.194
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0032 0.0184 0.0558
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0771 0.772 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0189 0.0229
Echinococcus multilocularis calmodulin 0.0025 0.0112 0.0112
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0136 0.1236 0.1343
Giardia lamblia Calmodulin 0.0025 0.0112 0.0269
Trypanosoma cruzi calmodulin, putative 0.0025 0.0112 0.0129
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0032 0.0184 0.0223
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0066 0.0066
Brugia malayi Serotonin receptor 0.0613 0.6105 1
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0192 0.1808 0.1808
Brugia malayi Blistered cuticle protein 3 0.0075 0.0621 0.1018
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0243 0.0243
Schistosoma mansoni biogenic amine (5HT) receptor 0.0916 0.9203 1
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0072 0.0585 0.0585
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0032 0.0184 0.0378
Plasmodium falciparum thioredoxin reductase 0.0276 0.2673 0.5628
Mycobacterium ulcerans endonuclease IV 0.0079 0.0664 0.2379
Giardia lamblia Rho GAP, putative 0.0066 0.0531 0.1709
Loa Loa (eye worm) neuropeptide F receptor 0.0136 0.1236 0.2198
Loa Loa (eye worm) hypothetical protein 0.0195 0.1844 0.3282
Schistosoma mansoni voltage-gated potassium channel 0.0076 0.0625 0.0679
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0287 0.0312
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0134 0.1215 0.1991
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0073 0.0601 0.0764
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0066 0.0109
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.01 0.0135
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.012 0.012
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0066 0.0109
Schistosoma mansoni hypothetical protein 0.0071 0.0577 0.0627
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.026 0.026
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0036 0.0224 0.0367
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0073 0.0601 0.1205
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Brugia malayi hypothetical protein 0.0024 0.0094 0.0154
Mycobacterium ulcerans epimerase 0.0021 0.0066 0.0111
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0012 0.0012
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0282 0.0282
Schistosoma mansoni metabotropic glutamate receptor 0.0024 0.0094 0.0102
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0994 1 1
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0036 0.0224 0.0224
Schistosoma mansoni chromobox protein 0.0072 0.059 0.0641
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0328 0.041
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0102 0.0898 0.1597
Echinococcus multilocularis chromobox protein 1 0.0072 0.059 0.059
Brugia malayi Dopamine receptor 0.0136 0.1236 0.2024
Brugia malayi glutathione reductase 0.0477 0.4721 0.7733
Brugia malayi Pre-SET motif family protein 0.0419 0.413 0.6765
Schistosoma mansoni opsin-like receptor 0.0136 0.1236 0.1343
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0036 0.0224 0.0224
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0032 0.0184 0.0378
Echinococcus multilocularis tyrosine protein kinase Fgr 0.004 0.026 0.026
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2586 0.5474
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.1236 0.1343
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0102 0.0898 0.115
Echinococcus granulosus N chimaerin 0.0015 0.0001 0.0001
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0036 0.0224 0.0243
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0243
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0036 0.0224 0.0367
Brugia malayi SET domain containing protein 0.0015 0.0002 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0601 0.0764
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0073 0.0601 0.0764
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0136 0.1236 0.1343
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0136 0.1236 0.2198
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Toxoplasma gondii hypothetical protein 0.0043 0.0287 0.0534
Brugia malayi G-protein coupled receptor 0.0136 0.1236 0.2024
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0303 0.2946 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0276 0.2673 0.5628
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0192 0.1808 0.1808
Brugia malayi hypothetical protein 0.0136 0.1236 0.2024
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.01 0.0135
Trypanosoma cruzi calmodulin, putative 0.0025 0.0112 0.0129
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.026 0.026
Brugia malayi Protein kinase domain containing protein 0.0051 0.0368 0.0603
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0018 0.0037 0.0032
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Echinococcus multilocularis RUN 0.0041 0.027 0.027
Brugia malayi cytochrome P450 0.0032 0.0184 0.0301
Trypanosoma cruzi extracellular receptor, putative 0.0024 0.0094 0.0106
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0066 0.0066
Mycobacterium ulcerans hypothetical protein 0.0029 0.0151 0.0432
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0276 0.2673 0.5628
Trichomonas vaginalis set domain proteins, putative 0.0477 0.472 1
Chlamydia trachomatis DNA gyrase subunit A 0.0031 0.0171 0.0275
Onchocerca volvulus 0.0081 0.0677 0.1313
Schistosoma mansoni hypothetical protein 0.0033 0.0188 0.0204
Treponema pallidum hypothetical protein 0.0024 0.0098 0.0161
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0036 0.0224 0.0243
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0036 0.0224 0.04
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0052 0.0032
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.005 0.0364 0.124
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0551 0.0903
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0032 0.0184 0.0378
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0036 0.0224 0.0367
Echinococcus multilocularis insulin receptor 0.0051 0.0368 0.0368
Loa Loa (eye worm) voltage-gated calcium channel 0.0036 0.0224 0.0397
Brugia malayi RhoGAP domain containing protein 0.0077 0.0639 0.1046
Loa Loa (eye worm) hypothetical protein 0.0043 0.0287 0.0509
Schistosoma mansoni voltage-gated potassium channel 0.0076 0.0625 0.0679
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0116
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0045 0.0311 0.051
Echinococcus multilocularis short transient receptor potential channel 6 0.0037 0.0227 0.0227
Plasmodium vivax DNA gyrase subunit B, putative 0.0085 0.0715 0.1449
Echinococcus granulosus nmda type glutamate receptor 0.0105 0.0928 0.0928
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0243
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0224 0.0224
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0066 0.0116
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0041 0.0276 0.0489
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0052 0.0063
Loa Loa (eye worm) hypothetical protein 0.0442 0.4366 0.7771
Trypanosoma brucei calmodulin 0.0025 0.0112 0.0129
Schistosoma mansoni neuropeptide receptor 0.0136 0.1236 0.1343
Schistosoma mansoni tyrosine kinase 0.0156 0.1442 0.1567
Echinococcus granulosus two pore calcium channel protein 2 0.0036 0.0224 0.0224
Echinococcus multilocularis voltage dependent calcium channel 0.0134 0.1215 0.1215
Schistosoma mansoni sodium/chloride dependent transporter 0.0043 0.0296 0.0322
Echinococcus granulosus chromobox protein 1 0.0072 0.059 0.059
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0032 0.0184 0.0558
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0036 0.0216 0.0216
Brugia malayi protein-tyrosine kinase 0.0036 0.0221 0.0362
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0109 0.022
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0098 0.0852 0.1689
Echinococcus granulosus serotonin transporter 0.0251 0.2412 0.2412
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0136 0.1236 0.2024
Echinococcus granulosus sodium and chloride dependent glycine 0.0043 0.0287 0.0287
Schistosoma mansoni glutamate receptor NMDA 0.0273 0.2642 0.2871
Echinococcus multilocularis voltage dependent calcium channel 0.0134 0.1215 0.1215
Mycobacterium tuberculosis Probable reductase 0.0181 0.1697 0.3587
Echinococcus multilocularis jun protein 0.0087 0.0741 0.0741
Echinococcus multilocularis receptor type guanylyl cyclase 0.0029 0.0149 0.0149
Echinococcus multilocularis calmodulin 0.0025 0.0112 0.0112
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0073 0.0601 0.1264
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0276 0.2673 1
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0041 0.0276 0.0299
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0136 0.1236 0.1343
Loa Loa (eye worm) serotonin transporter b 0.0251 0.2412 0.4291
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0032 0.0184 0.0378
Loa Loa (eye worm) neuropeptide F receptor 0.0136 0.1236 0.2198
Leishmania major mitochondrial DNA topoisomerase II 0.0163 0.1513 0.1947
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Echinococcus multilocularis N chimaerin 0.0015 0.0001 0.0001
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.1116 0.1985
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0036 0.0216 0.0264
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0042 0.0078
Loa Loa (eye worm) ion channel NompC 0.0036 0.0224 0.0397
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.001 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0018 0.0037 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0206 0.0427
Echinococcus granulosus orexin receptor type 2 0.0136 0.1236 0.1236
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0073 0.0601 0.0764
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0136 0.1236 0.1236
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0036 0.0224 0.0367
Brugia malayi hypothetical protein 0.0017 0.0025 0.004
Schistosoma mansoni microtubule-associated protein tau 0.0716 0.7156 0.7776
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0276 0.0574
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0287 0.047
Echinococcus multilocularis survival motor neuron protein 1 0.0245 0.2355 0.2355
Onchocerca volvulus 0.0136 0.1236 0.2513
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0066 0.0066
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0036 0.0224 0.0367
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0066 0.0066
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0041 0.0276 0.0299
Schistosoma mansoni sodium/chloride dependent transporter 0.0251 0.2412 0.262
Echinococcus granulosus sex peptide receptor 0.0136 0.1236 0.1236
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0032 0.0184 0.0558
Echinococcus granulosus tumor protein p63 0.035 0.3429 0.3429
Echinococcus granulosus epidermal growth factor receptor 0.0156 0.1442 0.1442
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0073 0.0601 0.0764
Loa Loa (eye worm) ryanodine receptor 0.0036 0.0224 0.0397
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0097
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0066 0.0066
Echinococcus multilocularis sex peptide receptor 0.0136 0.1236 0.1236
Echinococcus granulosus nmda type glutamate receptor 0.0193 0.182 0.182
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0148 0.1364 0.288
Echinococcus multilocularis potassium large conductance calcium activated 0.0036 0.0224 0.0224
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0589 0.5866 0.7596
Echinococcus multilocularis peregrin 0.003 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0251 0.2412 0.4291
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0287 0.0312
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0109 0.0221
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0066 0.0111
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0551 0.0699
Echinococcus granulosus neuropeptide receptor 0.0136 0.1236 0.1236
Brugia malayi jmjC domain containing protein 0.0038 0.0243 0.0398
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1646 0.348
Brugia malayi hypothetical protein 0.0041 0.027 0.0442
Echinococcus granulosus g protein coupled receptor 0.0136 0.1236 0.1236
Echinococcus multilocularis neuropeptide receptor A26 0.0613 0.6105 0.6105
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0032 0.0184 0.0378
Onchocerca volvulus 0.0072 0.0592 0.1131
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0287 0.0312
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0224 0.0243
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0672 0.6713 0.6713
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0066 0.0116
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.027 0.027
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0073 0.0601 0.1263
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0073 0.0601 0.2141
Mycobacterium ulcerans ferredoxin reductase 0.0073 0.0601 0.2141
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0224 0.0243
Treponema pallidum NADH oxidase 0.0276 0.2673 0.9056
Leishmania major calmodulin, putative 0.0025 0.0112 0.0129
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0662 0.6609 0.856
Schistosoma mansoni sulfide quinone reductase 0.0073 0.0601 0.0653
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0328 0.041
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0481 0.4764 0.4764
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0189 0.0189
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0276 0.2673 0.2673
Loa Loa (eye worm) glutathione reductase 0.0477 0.4721 0.8403
Echinococcus granulosus sodium channel protein 0.0442 0.4359 0.4359
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0066 0.0072
Loa Loa (eye worm) hypothetical protein 0.0041 0.027 0.0478
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0251 0.2412 0.262
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0073 0.0601 0.1205
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0085 0.0717 0.2582
Loa Loa (eye worm) hypothetical protein 0.0045 0.0311 0.0553
Brugia malayi hypothetical protein 0.0041 0.027 0.0442
Echinococcus granulosus geminin 0.0176 0.1646 0.1646
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0145 0.1332 0.1332
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0206 0.0427
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0188 0.0188
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0073 0.0601 0.0601
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0472 0.0512
Brugia malayi follicle stimulating hormone receptor 0.0136 0.1236 0.2024
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Echinococcus multilocularis neuropeptide receptor 0.0136 0.1236 0.1236
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.027 0.027
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0066 0.0109
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0287 0.0534
Entamoeba histolytica disulphide oxidoreductase, putative 0.0073 0.0601 0.194
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0243 0.0431
Echinococcus granulosus potassium large conductance calcium activated 0.0036 0.0224 0.0224
Trypanosoma brucei calmodulin 0.0025 0.0112 0.0129
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0134 0.1215 0.1215
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0136 0.1236 0.2024
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0066 0.0066
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0188 0.0308
Brugia malayi Metabotropic glutamate receptor precursor. 0.0024 0.0094 0.0154
Brugia malayi hypothetical protein 0.0136 0.1236 0.2024
Schistosoma mansoni transient receptor potential channel 0.0036 0.0224 0.0243
Echinococcus granulosus thioredoxin glutathione reductase 0.0477 0.4721 0.4721
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0032 0.0184 0.0558
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0297 0.0497
Echinococcus granulosus dro:myosuppressin receptor 0.0136 0.1236 0.1236
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0081 0.0677 0.1313
Echinococcus granulosus tyrosine protein kinase HCK 0.0032 0.0181 0.0181
Toxoplasma gondii transporter, cation channel family protein 0.0036 0.0224 0.04
Toxoplasma gondii hypothetical protein 0.0043 0.0287 0.0534
Loa Loa (eye worm) TK protein kinase 0.0036 0.0221 0.0392
Loa Loa (eye worm) hypothetical protein 0.0026 0.012 0.0211
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0134 0.1215 0.1215
Trichomonas vaginalis chromobox protein, putative 0.0072 0.059 0.124
Echinococcus multilocularis 0.0048 0.0341 0.0341
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.049 0.087
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0052 0.0051
Treponema pallidum fructose-bisphosphate aldolase 0.0303 0.2946 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0192 0.1808 0.1808
Schistosoma mansoni hypothetical protein 0.005 0.0363 0.0394
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0032 0.0184 0.0558
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0203 0.1924 0.3152
Schistosoma mansoni tyrosine kinase 0.0084 0.0712 0.0773
Schistosoma mansoni hypothetical protein 0.0072 0.0585 0.0636
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0042 0.0078
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0073 0.0601 0.2097
Mycobacterium leprae conserved hypothetical protein 0.0024 0.01 0.0092
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0136 0.1236 0.1343
Brugia malayi bZIP transcription factor family protein 0.0087 0.0741 0.1214
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Trichomonas vaginalis xanthine dehydrogenase, putative 0.018 0.1686 0.3566
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0036 0.0224 0.0243
Schistosoma mansoni transient receptor potential channel 4 0.0036 0.0224 0.0243
Loa Loa (eye worm) inositol-1 0.0038 0.0243 0.0431
Echinococcus multilocularis L aminoadipate semialdehyde 0.0086 0.0732 0.0732
Brugia malayi putative neuropeptide receptor 0.0136 0.1236 0.2024
Schistosoma mansoni jumonji domain containing protein 0.0079 0.0655 0.0712
Echinococcus granulosus transcription factor Dp 1 0.004 0.0257 0.0257
Trichomonas vaginalis calmodulin, putative 0.0025 0.0112 0.0226
Loa Loa (eye worm) hypothetical protein 0.0066 0.0531 0.0943
Brugia malayi Transient-receptor-potential like protein 0.0036 0.0224 0.0367
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0036 0.0216 0.0264
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0073 0.0601 0.1264
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0109 0.0221
Loa Loa (eye worm) hypothetical protein 0.0388 0.3813 0.6787
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0032 0.0184 0.0378
Onchocerca volvulus 0.0136 0.1236 0.2513
Trichomonas vaginalis aldehyde oxidase, putative 0.018 0.1686 0.3566
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0073 0.0601 0.0601
Echinococcus granulosus tyrosine protein kinase Src64B 0.004 0.026 0.026
Echinococcus multilocularis serotonin transporter 0.0251 0.2412 0.2412
Brugia malayi Cytochrome P450 family protein 0.0032 0.0184 0.0301
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0051 0.0368 0.0368
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Schistosoma mansoni loxhd1 0.0041 0.027 0.0293
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0036 0.0224 0.0224
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0328 0.1002
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0041 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Toxoplasma gondii Erv1 / Alr family protein 0.0036 0.0216 0.0382
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0066 0.0072
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0073 0.0601 0.195
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0202 0.0418
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0662 0.6609 0.856
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0206 0.0427
Schistosoma mansoni polycystin 1-related 0.0041 0.027 0.0293
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0052 0.0057
Trypanosoma brucei calmodulin 0.0025 0.0112 0.0129
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0042 0.0078
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0589 0.5866 0.7596
Schistosoma mansoni biogenic amine receptor 0.0136 0.1236 0.1343
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0052 0.0084
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0041 0.0276 0.0276
Echinococcus granulosus cytochrome P450 2K1 0.0032 0.0184 0.0184
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0061 0.0472 0.165
Schistosoma mansoni tyrosine kinase 0.0026 0.0114 0.0124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0134 0.0273
Echinococcus granulosus metabotropic glutamate receptor 2 0.0024 0.0094 0.0094
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0032 0.0184 0.0378
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0073 0.0601 0.0601
Echinococcus multilocularis short transient receptor potential channel 6 0.0036 0.0224 0.0224
Brugia malayi Cytochrome P450 family protein 0.005 0.0364 0.0596
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0012 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0192 0.1808 0.1808
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0052 0.0051
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.027 0.027
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0224 0.0224
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0384 0.3768 0.798
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0243 0.0505
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0066 0.0001
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0243 0.0441
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.0269 0.0269
Schistosoma mansoni glutamate receptor AMPA 0.0168 0.1566 0.1702
Schistosoma mansoni hypothetical protein 0.0176 0.1646 0.1788
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0036 0.0216 0.0382
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0039 0.0253 0.082
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0072 0.0589 0.1046
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0073 0.0601 0.0985
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0268 0.2586 0.4236
Plasmodium vivax DNA topoisomerase II, putative 0.0145 0.1332 0.2765
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0012 0.0015
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0224 0.0243
Schistosoma mansoni cpg binding protein 0.0031 0.0174 0.0189
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0243 0.0784
Echinococcus granulosus g protein coupled receptor 0.0136 0.1236 0.1236
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1646 0.348
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0376 0.0408
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0551 0.0551
Echinococcus multilocularis tyrosine protein kinase Src64B 0.004 0.026 0.026
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0189 0.0189
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0072 0.0589 0.0589
Schistosoma mansoni disulfide oxidoreductase 0.0073 0.0601 0.0653
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.0201 0.0201
Echinococcus multilocularis chromobox protein 1 0.0072 0.059 0.059
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0073 0.0601 0.0601
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0066 0.0072
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0145 0.1332 0.2182
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.027 0.0498
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0243
Onchocerca volvulus Neuropeptide F receptor homolog 0.0136 0.1236 0.2513
Echinococcus granulosus mitogen activated protein kinase 3 0.0102 0.0898 0.0898
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Schistosoma mansoni sulfide quinone reductase 0.0073 0.0601 0.0653
Schistosoma mansoni tyrosine kinase 0.0051 0.0368 0.04
Brugia malayi GnHR receptor homolog 0.0136 0.1236 0.2024
Brugia malayi jmjC domain containing protein 0.0099 0.0863 0.1414
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.004 0.026 0.026
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0072 0.0589 0.0589
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0136 0.1236 0.2024
Schistosoma mansoni glutamate receptor NMDA 0.034 0.3319 0.3607
Brugia malayi Probable DNA topoisomerase II 0.0145 0.1332 0.2182
Loa Loa (eye worm) hypothetical protein 0.0024 0.0094 0.0165
Brugia malayi Dopamine receptor protein 2 0.0136 0.1236 0.2024
Brugia malayi ecdysteroid receptor 0.0021 0.0066 0.0109
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0032 0.0184 0.0558
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0276 0.2673 0.3452
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.0898 0.115
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1646 0.348
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0109 0.0221
Giardia lamblia Thioredoxin reductase 0.0073 0.0601 0.195
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0073 0.0601 0.1264
Loa Loa (eye worm) hypothetical protein 0.004 0.0266 0.0471
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0297 0.062
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0048 0.0339 0.0708
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0419 0.413 0.735
Brugia malayi hypothetical protein 0.0043 0.0287 0.047
Loa Loa (eye worm) hypothetical protein 0.0025 0.0109 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0231 0.0479
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0035 0.0213 0.0261
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2946 0.6238
Brugia malayi cation channel family protein 0.0036 0.0224 0.0367
Onchocerca volvulus 0.0136 0.1236 0.2513
Schistosoma mansoni neuropeptide receptor 0.0136 0.1236 0.1343
Echinococcus granulosus shaker cognate 0.0036 0.0224 0.0224
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0026 0.0114 0.0201
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0472 0.0929
Onchocerca volvulus 0.0032 0.0177 0.0238
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0161 0.0331
Schistosoma mansoni amine GPCR 0.0651 0.6494 0.7057
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0073 0.0601 0.1263
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0072 0.0585 0.0585
Loa Loa (eye worm) CYP4Cod1 0.005 0.0364 0.0645
Echinococcus granulosus glutamate receptor subunit protein glur 0.0072 0.0585 0.0585
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0066 0.0109
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.027 0.0498
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0032 0.0184 0.0378
Onchocerca volvulus 0.0136 0.1236 0.2513
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.0227 0.0227
Echinococcus multilocularis neuropeptide Y receptor 0.0136 0.1236 0.1236
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0032 0.0184 0.0558
Trypanosoma cruzi cytochrome P450, putative 0.005 0.0364 0.0456
Echinococcus multilocularis G protein coupled receptor 139 0.0136 0.1236 0.1236
Schistosoma mansoni two-pore calcium channel 0.0036 0.0224 0.0243
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0055
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0032 0.0184 0.0558
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0188 0.0308
Plasmodium falciparum DNA gyrase subunit B 0.0085 0.0715 0.1449
Brugia malayi Receptor family ligand binding region containing protein 0.0029 0.0149 0.0244
Brugia malayi Glutamate receptor 2 precursor 0.0168 0.1566 0.2566
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0136 0.1236 0.1343
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0036 0.0221 0.0221
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0059 0.0454 0.0807
Plasmodium falciparum calmodulin 0.0025 0.0112 0.016
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0051 0.0056
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0189 0.0324
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0073 0.0601 0.1263
Echinococcus multilocularis allatostatin A receptor 0.0136 0.1236 0.1236
Brugia malayi MH2 domain containing protein 0.0124 0.1116 0.1828
Mycobacterium ulcerans glutamate synthase subunit beta 0.0073 0.0601 0.2141
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0224 0.0224
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0662 0.6609 0.856
Loa Loa (eye worm) hypothetical protein 0.022 0.2103 0.3742
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0243
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0287 0.047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0012 0.0015
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0066 0.0072
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0192 0.1808 0.1808
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0066 0.0109
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0034 0.0203 0.0418
Echinococcus granulosus hyperpolarization activated cyclic 0.0041 0.0276 0.0276
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1646 0.348
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Onchocerca volvulus Glucosylceramidase homolog 0.0176 0.1646 0.3393
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0145 0.1332 0.2182
Brugia malayi neuropeptide F receptor 0.0136 0.1236 0.2024
Mycobacterium ulcerans monoxygenase 0.0073 0.0601 0.2141
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.004 0.026 0.026
Schistosoma mansoni voltage-dependent calcium channel 0.0036 0.0224 0.0243
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0136 0.1236 0.2513
Echinococcus multilocularis neuropeptide Y receptor 0.0136 0.1236 0.1236
Loa Loa (eye worm) hypothetical protein 0.0043 0.0287 0.0509
Echinococcus granulosus hypothetical protein 0.0851 0.8539 0.8539
Schistosoma mansoni coup transcription factor 0.0021 0.0066 0.0072
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0048 0.0339 0.0708
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Trypanosoma brucei ABC transporter, putative 0.0018 0.0037 0.0032
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0328 0.041
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Trichomonas vaginalis glutathione reductase, putative 0.0276 0.2673 0.5658
Echinococcus granulosus tyrosine kinase 0.0036 0.0221 0.0221
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.034 0.3319 0.3319
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0328 0.0582
Mycobacterium tuberculosis Probable oxidoreductase 0.0384 0.3768 0.798
Echinococcus multilocularis tyrosine protein kinase Src42A 0.004 0.026 0.026
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0243
Echinococcus granulosus epidermal growth factor receptor 0.0084 0.0712 0.0712
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0276 0.2673 1
Schistosoma mansoni eyes absent homolog 0.0092 0.0794 0.0863
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0032 0.0184 0.0558
Loa Loa (eye worm) cytochrome P450 family protein 0.005 0.0364 0.0645
Loa Loa (eye worm) hypothetical protein 0.0025 0.0112 0.0197
Onchocerca volvulus 0.0136 0.1236 0.2513
Loa Loa (eye worm) hypothetical protein 0.0382 0.375 0.6674
Echinococcus granulosus fmrfamide receptor 0.0136 0.1236 0.1236
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0066 0.0072
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0551 0.0551
Trypanosoma cruzi ABC transporter, putative 0.0018 0.0037 0.0032
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0224 0.0224
Schistosoma mansoni alpha-1 adrenergic receptor 0.0136 0.1236 0.1343
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0032 0.0184 0.0558
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1742 0.3685
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0149 0.0244
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0136 0.1236 0.1236
Brugia malayi G protein-coupled receptor F59B2.13 0.0136 0.1236 0.2024
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Leishmania major cytochrome p450-like protein 0.005 0.0364 0.0456
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0053 0.0396 0.1364
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0243 0.0505
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0206 0.0362
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0145 0.1332 0.1332
Schistosoma mansoni voltage-gated cation channel 0.0134 0.1215 0.1321
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0149 0.0263
Echinococcus multilocularis nmda type glutamate receptor 0.0105 0.0928 0.0928
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0073 0.0601 0.0764
Loa Loa (eye worm) hypothetical protein 0.0037 0.0227 0.0402
Echinococcus multilocularis calmodulin 0.0025 0.0112 0.0112
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0243 0.0264
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0328 0.0685
Echinococcus multilocularis mitogen activated protein kinase 0.0102 0.0898 0.0898
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0072 0.0585 0.0585
Echinococcus granulosus lamin 0.0054 0.0406 0.0406
Brugia malayi hypothetical protein 0.0036 0.0224 0.0367
Echinococcus multilocularis tyrosine kinase 0.0026 0.0114 0.0114
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0276 0.2673 0.3452
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0066 0.0116
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0066 0.0072
Toxoplasma gondii transporter, cation channel family protein 0.0055 0.0411 0.08
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Toxoplasma gondii Erv1 / Alr family protein 0.0036 0.0216 0.0382
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0243
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0079 0.0664 0.1339
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2946 0.6238
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.01 0.0114
Schistosoma mansoni hypothetical protein 0.0041 0.027 0.0293
Echinococcus granulosus ATP binding cassette sub family G 0.0018 0.0037 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0328 0.0685
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0102 0.0898 0.1839
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0188 0.0188
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0036 0.0224 0.0367
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.026 0.026
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0188 0.0188
Onchocerca volvulus 0.005 0.0363 0.0638
Brugia malayi hypothetical protein 0.0068 0.055 0.0902
Echinococcus granulosus voltage gated hydrogen channel 1 0.0036 0.0224 0.0224
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0034 0.0203 0.063
Schistosoma mansoni hypothetical protein 0.0136 0.1236 0.1343
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0276 0.2673 0.2904
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0042 0.0078
Onchocerca volvulus 0.0086 0.0732 0.1432
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.01 0.024
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0156 0.0277
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0161 0.0285
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0116
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Schistosoma mansoni neuropeptide receptor 0.0136 0.1236 0.1343
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0043 0.0287 0.0509
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0328 0.0328
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0328 0.0537
Echinococcus multilocularis transfer RNA-Gly 0.0036 0.0224 0.0224
Echinococcus granulosus voltage gated potassium channel 0.0036 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0085 0.0717 0.1274
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.1236 0.1343
Schistosoma mansoni neuropeptide f receptor 76f 0.0136 0.1236 0.1343
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0036 0.0224 0.0224
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0136 0.1236 0.1236
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0073 0.0601 0.0764
Schistosoma mansoni hypothetical protein 0.0136 0.1236 0.1343
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.0227 0.0227
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0328 0.041
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0072 0.0592 0.0644
Brugia malayi Heterochromatin protein 1 0.0072 0.059 0.0966
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.026 0.026
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0189 0.0229
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0036 0.0216 0.0264
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0041 0.0276 0.0299
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0073 0.0601 0.0601
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0073 0.0601 0.0985
Onchocerca volvulus 0.0136 0.1236 0.2513
Brugia malayi ABC transporter family protein 0.0015 0.0009 0.0014
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0098 0.0852 0.1689
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0041 0.0276 0.0299
Schistosoma mansoni hypothetical protein 0.0136 0.1236 0.1343
Mycobacterium leprae Conserved hypothetical protein 0.0032 0.0184 0.0319
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0066 0.0109
Echinococcus granulosus calmodulin 0.0025 0.0112 0.0112
Schistosoma mansoni glutamate synthase 0.0073 0.0601 0.0653
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0224 0.0224
Schistosoma mansoni ABC transporter 0.0015 0.0009 0.001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Schistosoma mansoni glutamate synthase 0.0073 0.0601 0.0653
Entamoeba histolytica hypothetical protein 0.0024 0.01 0.0218
Loa Loa (eye worm) hepatopoietin HPO2 0.0036 0.0216 0.0382
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0073 0.0601 0.0601
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0035 0.0213 0.0261
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0898 0.1894
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0137 0.1252 0.1609
Plasmodium falciparum DNA topoisomerase 2 0.0145 0.1332 0.2765
Loa Loa (eye worm) ABC transporter 0.0015 0.0009 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0172 0.0353
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.0227 0.0227
Loa Loa (eye worm) hypothetical protein 0.0081 0.0677 0.1204
Schistosoma mansoni tyrosine kinase 0.0082 0.0692 0.0751
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0043 0.0287 0.0287
Brugia malayi steroid hormone receptor 0.0021 0.0066 0.0109
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.004 0.026 0.026
Schistosoma mansoni growth hormone secretagogue receptor 0.0136 0.1236 0.1343
Echinococcus multilocularis sodium and chloride dependent glycine 0.0043 0.0287 0.0287
Echinococcus multilocularis two pore calcium channel protein 2 0.0036 0.0224 0.0224
Echinococcus granulosus 7tm_1 domain containing protein 0.0136 0.1236 0.1236
Loa Loa (eye worm) hypothetical protein 0.0134 0.1215 0.2162
Schistosoma mansoni unc-13 (munc13) 0.0015 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0033 0.0188 0.0204
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2946 0.6238
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0018 0.0037 0.0032
Echinococcus granulosus jun protein 0.0087 0.0741 0.0741
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0073 0.0601 0.1068
Brugia malayi larval opioid receptor 0.0136 0.1236 0.2024
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0328 0.0356
Schistosoma mansoni glutamate receptor AMPA 0.0168 0.1566 0.1702
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0276 0.2673 1
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0039 0.0253 0.0696
Echinococcus multilocularis neuropeptide receptor 0.0136 0.1236 0.1236
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0066 0.0116
Onchocerca volvulus 0.0025 0.0111 0.0098
Schistosoma mansoni tyrosine kinase 0.0082 0.0692 0.0751
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0073 0.0601 0.1205
Echinococcus multilocularis ATP binding cassette sub family G 0.0018 0.0037 0.0037
Schistosoma mansoni lipoxygenase 0.0106 0.0934 0.1015
Schistosoma mansoni myosin xvIII 0.0136 0.1236 0.1343
Giardia lamblia PHD finger protein 15 0.003 0.0161 0.0439
Plasmodium falciparum thioredoxin reductase 0.0477 0.4721 1
Schistosoma mansoni opsin-like receptor 0.0136 0.1236 0.1343
Echinococcus granulosus dnaJ subfamily B 0.0424 0.4181 0.4181
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0136 0.1236 0.1343
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0224 0.0224
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0276 0.2673 0.2673
Echinococcus multilocularis tyrosine protein kinase HCK 0.0032 0.0181 0.0181
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0036 0.0224 0.0224
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0916 0.9203 0.9203
Chlamydia trachomatis DNA gyrase subunit B 0.0067 0.0534 0.1687
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0066 0.0066
Echinococcus multilocularis tumor protein p63 0.035 0.3429 0.3429
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0095 0.0817 0.1045
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0042 0.0078
Echinococcus multilocularis calmodulin 0.0025 0.0112 0.0112
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0224 0.0224
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0161 0.0161
Brugia malayi Melatonin receptor type 1A 0.0136 0.1236 0.2024
Treponema pallidum sodium- and chloride- dependent transporter 0.0251 0.2412 0.8154
Brugia malayi Pre-SET motif family protein 0.0061 0.0472 0.0773
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0276 0.2673 0.5628
Brugia malayi G protein-coupled receptor 0.0136 0.1236 0.2024
Brugia malayi nuclear receptor NHR-88 0.0021 0.0066 0.0109
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0136 0.1236 0.2198
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0224 0.0224
Echinococcus multilocularis neuropeptide FF receptor 2 0.0136 0.1236 0.1236
Onchocerca volvulus 0.0136 0.1236 0.2513
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0231 0.0479
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0231 0.0284
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0085 0.0715 0.2293
Schistosoma mansoni rac gtpase activating protein 0.0077 0.0639 0.0694
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Echinococcus multilocularis calmodulin 0.0025 0.0111 0.0111
Loa Loa (eye worm) TOPoisomerase family member 0.0145 0.1332 0.2369
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0192 0.1808 0.1808
Toxoplasma gondii DNA topoisomerase 2, putative 0.0145 0.1332 0.2765
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0189 0.0189
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0043 0.0287 0.0287
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0384 0.3768 0.798
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0328 0.0685
Loa Loa (eye worm) hypothetical protein 0.0032 0.0177 0.0312
Plasmodium vivax hypothetical protein, conserved 0.003 0.0161 0.0266
Echinococcus granulosus calcium activated potassium channel 0.0037 0.0234 0.0234
Schistosoma mansoni tyrosine kinase 0.0026 0.0114 0.0124
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0136 0.1236 0.2198
Giardia lamblia NADH oxidase lateral transfer candidate 0.0276 0.2673 0.9062
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0287 0.0534
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Brugia malayi hypothetical protein 0.0136 0.1236 0.2024
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1646 0.348
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0084 0.0712 0.0712
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0472 0.0512
Mycobacterium ulcerans hypothetical protein 0.0021 0.0066 0.0111
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0181 0.1697 0.4405
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0224 0.0224
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0036 0.0224 0.0367
Leishmania major hypothetical protein, conserved 0.0036 0.0216 0.0264
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0287 0.0312
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2586 0.5474
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Echinococcus granulosus voltage gated potassium channel 0.0045 0.0311 0.0311
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0073 0.0601 0.0601
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.026 0.026
Brugia malayi hypothetical protein 0.0136 0.1236 0.2024
Leishmania major DNA topoisomerase ii 0.0137 0.1252 0.1609
Loa Loa (eye worm) hypothetical protein 0.0077 0.0639 0.1135
Trypanosoma cruzi DNA topoisomerase II, putative 0.0137 0.1252 0.1609
Schistosoma mansoni hypothetical protein 0.0036 0.0224 0.0243
Loa Loa (eye worm) hypothetical protein 0.0059 0.0454 0.0807
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0119 0.0139
Brugia malayi Cytochrome P450 family protein 0.0052 0.0388 0.0635
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0231 0.0479
Leishmania major hypothetical protein, conserved 0.0073 0.0601 0.0764
Schistosoma mansoni rab6-interacting 0.0041 0.027 0.0293
Schistosoma mansoni intermediate filament proteins 0.0054 0.0406 0.0441
Onchocerca volvulus 0.003 0.0156 0.0195
Schistosoma mansoni calmodulin 0.0025 0.0112 0.0121
Brugia malayi Guanylyl cyclase protein 23 0.0029 0.0149 0.0244
Schistosoma mansoni calcium-activated potassium channel 0.0036 0.0224 0.0243
Echinococcus granulosus neuropeptides capa receptor 0.0136 0.1236 0.1236
Mycobacterium leprae putative cytochrome p450 0.0032 0.0184 0.0319
Onchocerca volvulus 0.0054 0.0406 0.073
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0188 0.0333
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0134 0.1215 0.1215
Toxoplasma gondii NADPH-glutathione reductase 0.0276 0.2673 0.5628
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0472 0.0472
Toxoplasma gondii hypothetical protein 0.0036 0.0224 0.04
Echinococcus granulosus tyrosine protein kinase Blk 0.0036 0.0221 0.0221
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.059 0.1048
Echinococcus granulosus metabotropic glutamate receptor 5 0.0024 0.0094 0.0094
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0119 0.0176
Echinococcus multilocularis serotonin receptor 0.0388 0.3813 0.3813
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Schistosoma mansoni DNA topoisomerase II 0.0145 0.1332 0.1447
Entamoeba histolytica hypothetical protein 0.0024 0.0094 0.0196
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0104 0.0913 0.1496
Loa Loa (eye worm) hypothetical protein 0.0079 0.0664 0.118
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0073 0.0601 0.0601
Loa Loa (eye worm) hypothetical protein 0.0043 0.0287 0.0509
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0601 0.0764
Loa Loa (eye worm) hypothetical protein 0.0018 0.004 0.0069
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0073 0.0601 0.1205
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0134 0.1215 0.1321
Echinococcus granulosus Rac GTPase activating protein 1 0.0077 0.0639 0.0639
Loa Loa (eye worm) SRC-1 0.004 0.026 0.0461
Loa Loa (eye worm) hypothetical protein 0.0024 0.0094 0.0165
Echinococcus granulosus alpha 1A adrenergic receptor 0.0136 0.1236 0.1236
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0073 0.0601 0.1264
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0145 0.0297
Onchocerca volvulus 0.0136 0.1236 0.2513
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0073 0.0601 0.1446
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0189 0.0334
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0243 0.0505
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.0898 0.115
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1646 0.348
Echinococcus multilocularis cpg binding protein 0.0031 0.0174 0.0174
Echinococcus granulosus ATP binding cassette sub family G 0.0018 0.0037 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0137 0.0279
Brugia malayi intermediate filament protein 0.0054 0.0406 0.0665
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0032 0.0184 0.0223
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2946 0.6238
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0189 0.0229
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0032 0.0184 0.0223
Schistosoma mansoni tyrosine kinase 0.0082 0.0692 0.0751
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0115
Brugia malayi chromobox protein homolog 3 0.004 0.0266 0.0435
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0137 0.0279
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0066 0.0072
Schistosoma mansoni biogenic amine receptor 0.0136 0.1236 0.1343
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0136 0.1236 0.1343
Echinococcus granulosus mitogen activated protein kinase 0.0102 0.0898 0.0898
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0066 0.0066
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0119 0.1067 0.391
Schistosoma mansoni tyrosine kinase 0.004 0.026 0.0282
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0551 0.0979
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0066 0.0108
Echinococcus granulosus glutamate receptor 2 0.012 0.1075 0.1075
Giardia lamblia Fructose-bisphosphate aldolase 0.0303 0.2946 1
Brugia malayi Cytochrome P450 family protein 0.005 0.0364 0.0596
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0136 0.1236 0.2198
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0442 0.0442
Plasmodium falciparum DNA gyrase subunit A 0.0031 0.0171 0.0286
Plasmodium falciparum glutathione reductase 0.0477 0.4721 1
Leishmania major C-8 sterol isomerase-like protein 0.0382 0.375 0.4849
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0206 0.0427
Schistosoma mansoni tyrosine kinase 0.0084 0.0712 0.0773
Brugia malayi Cyclic-nucleotide gated cation channel 0.0041 0.0276 0.0451
Loa Loa (eye worm) adenylyl cyclase 3 0.0081 0.0677 0.1204
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0073 0.0601 0.1263
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0406 0.0721
Brugia malayi hypothetical protein 0.0136 0.1236 0.2024
Schistosoma mansoni sodium/chloride dependent transporter 0.0043 0.0287 0.0312
Plasmodium falciparum transporter, putative 0.0043 0.0287 0.0534
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0116
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0189 0.0309
Trypanosoma brucei ATP-binding cassette protein, putative 0.0018 0.0037 0.0032
Trypanosoma brucei protein kinase, putative 0.0102 0.0898 0.115
Trichomonas vaginalis chromobox protein, putative 0.0072 0.059 0.124
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0551 0.0599
Echinococcus granulosus hypothetical protein 0.0036 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0043 0.0287 0.0509
Treponema pallidum oxidoreductase 0.0073 0.0601 0.1899
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0086 0.0732 0.12
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0134 0.1215 0.1215
Brugia malayi PHD-finger family protein 0.003 0.0161 0.0264
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.1236 0.1343
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0036 0.0224 0.0224
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.1236 0.1343
Echinococcus multilocularis voltage gated potassium channel 0.0036 0.0224 0.0224
Echinococcus multilocularis geminin 0.0176 0.1646 0.1646
Schistosoma mansoni neuropeptide receptor 0.0136 0.1236 0.1343
Echinococcus granulosus lamin dm0 0.0054 0.0406 0.0406
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0161 0.0266
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0036 0.0224 0.034
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0224 0.2138 0.445
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0066 0.0072
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0266 0.043
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0066 0.0072
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.027 0.027
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0079 0.0664 0.1339
Loa Loa (eye worm) hypothetical protein 0.0033 0.0188 0.0333
Leishmania major NADH dehydrogenase, putative 0.0073 0.0601 0.0764
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0073 0.0601 0.0985
Echinococcus granulosus neuropeptide Y receptor 0.0136 0.1236 0.1236
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0015 0.0001 0.0001
Echinococcus multilocularis fmrfamide receptor 0.0136 0.1236 0.1236
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0073 0.0601 0.1263
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0276 0.2673 0.5657
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0036 0.0224 0.0224
Toxoplasma gondii selenide, water dikinase 0.0073 0.0601 0.1205
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0119 0.0139
Brugia malayi Glutamate receptor 1 precursor 0.0168 0.1566 0.2566
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0203 0.1924 0.3152
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0073 0.0601 0.2141
Echinococcus granulosus calmodulin 0.0025 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0051 0.0376 0.0667
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0032 0.0184 0.0378
Schistosoma mansoni voltage-gated potassium channel 0.004 0.026 0.0282
Toxoplasma gondii hypothetical protein 0.0036 0.0224 0.04
Echinococcus multilocularis microtubule associated protein 2 0.0716 0.7156 0.7156
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0066 0.0109
Brugia malayi Dopamine receptor protein 1 0.0565 0.5618 0.9202
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0042 0.0078
Schistosoma mansoni jun-related protein 0.0071 0.0575 0.0625
Echinococcus multilocularis conserved hypothetical protein 0.0036 0.0224 0.0224
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0243 0.03
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0189 0.0189
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0032 0.0184 0.0223
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0066 0.0116
Echinococcus granulosus neuropeptide s receptor 0.0613 0.6105 0.6105
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0043 0.0287 0.0287
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0189 0.0324
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0073 0.0601 0.194
Plasmodium falciparum glutathione reductase 0.0276 0.2673 0.5628
Entamoeba histolytica DNA topoisomerase II, putative 0.0145 0.1332 0.4452
Echinococcus multilocularis ryanodine receptor 44f 0.0036 0.0224 0.0224
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0601 0.0764
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0287 0.0312
Loa Loa (eye worm) TK/INSR protein kinase 0.0051 0.0368 0.0653
Brugia malayi CXXC zinc finger family protein 0.003 0.0156 0.0256
Plasmodium vivax glutathione reductase, putative 0.0477 0.4721 1
Echinococcus multilocularis transient receptor potential gamma protein 0.0036 0.0224 0.0224
Echinococcus multilocularis neuropeptides capa receptor 0.0136 0.1236 0.1236
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.027 0.027
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0149 0.0263
Schistosoma mansoni hypothetical protein 0.0424 0.4181 0.4543
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2586 0.5474
Echinococcus granulosus neuropeptide FF receptor 2 0.0136 0.1236 0.1236
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0231 0.0479
Mycobacterium ulcerans dehydrogenase 0.0073 0.0601 0.2141
Loa Loa (eye worm) hypothetical protein 0.0565 0.5618 1
Echinococcus granulosus intermediate filament protein 0.0054 0.0406 0.0406
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0032 0.0184 0.0378
Onchocerca volvulus 0.0136 0.1236 0.2513
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0382 0.375 0.4849
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0066 0.0116
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0018 0.0037 0.004
Trypanosoma cruzi calmodulin 0.0025 0.0112 0.0129
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Echinococcus multilocularis thioredoxin glutathione reductase 0.0477 0.4721 0.4721
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0006
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0251 0.2412 0.395
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0136 0.1236 0.1236
Echinococcus granulosus short transient receptor potential channel 6 0.0037 0.0227 0.0227
Leishmania major hypothetical protein, unknown function 0.0036 0.0224 0.0275
Brugia malayi latrophilin 2 splice variant baaae 0.0071 0.0577 0.0946
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0771 0.772 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0261 0.0462
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0206 0.0427
Schistosoma mansoni cpg binding protein 0.003 0.0156 0.017
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Mycobacterium ulcerans DNA gyrase subunit A 0.0031 0.0171 0.0509
Schistosoma mansoni cytochrome P450 0.0032 0.0184 0.02
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0032 0.0184 0.0558
Leishmania major cytochrome p450-like protein 0.0032 0.0184 0.0223
Echinococcus granulosus tm gpcr rhodopsin 0.0136 0.1236 0.1236
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Schistosoma mansoni sodium-dependent amino acid transporter 0.0043 0.0287 0.0312
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0136 0.1236 0.1236
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0073 0.0601 0.194
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0079 0.0664 0.1396
Onchocerca volvulus 0.0136 0.1236 0.2513
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.01 0.0135
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0099 0.0863 0.0863
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0043 0.0287 0.0287
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0073 0.0601 0.0601
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Echinococcus multilocularis hyperpolarization activated cyclic 0.0041 0.0276 0.0276
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0073 0.0601 0.1446
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0073 0.0601 0.1264
Echinococcus granulosus atrial natriuretic peptide receptor 0.0024 0.0094 0.0094
Trypanosoma brucei cytochrome P450, putative 0.005 0.0364 0.0456
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0328 0.041
Brugia malayi Furin-like cysteine rich region family protein 0.0156 0.1442 0.2362
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0257 0.0257
Brugia malayi Thioredoxin reductase 0.0477 0.4721 0.7733
Echinococcus granulosus hyperpolarization activated cyclic 0.0041 0.0276 0.0276
Brugia malayi RE15519p 0.0136 0.1236 0.2024
Echinococcus multilocularis ATP binding cassette sub family G 0.0018 0.0037 0.0037
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.026 0.026
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0066 0.0109
Onchocerca volvulus 0.0029 0.0149 0.0179
Loa Loa (eye worm) hypothetical protein 0.0018 0.004 0.0069
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0224 0.0224
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0041 0.0276 0.0276
Schistosoma mansoni hypothetical protein 0.0071 0.0575 0.0625
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0224 0.0224
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0073 0.0601 0.2141
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0163 0.1513 0.1947
Onchocerca volvulus 0.0136 0.1236 0.2513
Loa Loa (eye worm) calcium channel 0.0134 0.1215 0.2162
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0181 0.1697 0.3587
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Trichomonas vaginalis apoptosis inducing factor, putative 0.0073 0.0601 0.1264
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0041 0.0276 0.0299
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0036 0.0224 0.0224
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0287 0.0312
Onchocerca volvulus Alhambra homolog 0.003 0.0161 0.0204
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Echinococcus granulosus cpg binding protein 0.0031 0.0174 0.0174
Plasmodium falciparum ferrodoxin reductase-like protein 0.0073 0.0601 0.1205
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0043 0.0287 0.0287
Trypanosoma cruzi trypanothione reductase, putative 0.0477 0.4721 0.6109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0137 0.0279
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.018 0.1685 0.1685
Brugia malayi Calcitonin receptor-like protein seb-1 0.0104 0.0913 0.1496
Echinococcus multilocularis epidermal growth factor receptor 0.0156 0.1442 0.1442
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0898 0.1894
Loa Loa (eye worm) hypothetical protein 0.0251 0.2412 0.4291
Loa Loa (eye worm) TK/EGFR protein kinase 0.0156 0.1442 0.2565
Giardia lamblia DNA topoisomerase II 0.0137 0.1255 0.4194
Loa Loa (eye worm) hypothetical protein 0.0442 0.4366 0.7771
Echinococcus multilocularis lamin dm0 0.0054 0.0406 0.0406
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0771 0.772 1
Loa Loa (eye worm) G-protein coupled receptor 0.0136 0.1236 0.2198
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0287 0.047
Trypanosoma cruzi NADH dehydrogenase, putative 0.0073 0.0601 0.0764
Brugia malayi MAP kinase sur-1 0.0102 0.0898 0.1471
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0031 0.0171 0.0454
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0066 0.0001
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0119 0.0139
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0224 0.0243
Trichomonas vaginalis mercuric reductase, putative 0.0276 0.2673 0.5658
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0024 0.0094 0.0165
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.1236 0.1343
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0119 0.0176
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0303 0.2946 1
Echinococcus multilocularis shaker cognate 0.0036 0.0224 0.0224
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0551 0.0699
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0032 0.0184 0.0378
Loa Loa (eye worm) TK protein kinase 0.0032 0.0181 0.0321
Chlamydia trachomatis DNA gyrase subunit B 0.0085 0.0715 0.2391
Toxoplasma gondii exonuclease III APE 0.002 0.0052 0.0032
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0073 0.0601 0.1446
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0145 0.0297
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0032 0.0184 0.0378
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0243 0.03
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0052 0.009
Echinococcus granulosus receptor type guanylyl cyclase 0.0029 0.0149 0.0149
Trypanosoma brucei calmodulin 0.0025 0.0112 0.0129
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.1116 0.1985
Schistosoma mansoni hypothetical protein 0.0032 0.0184 0.02
Loa Loa (eye worm) glutamate receptor 2 0.0168 0.1566 0.2787
Trichomonas vaginalis DNA topoisomerase II, putative 0.0145 0.1332 0.2814
Toxoplasma gondii calmodulin, putative 0.0025 0.0112 0.016
Leishmania major extracellular receptor, putative 0.0024 0.0094 0.0106
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0015 0.0001 0.0001
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0551 0.0699
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0243
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0032 0.0184 0.0378
Schistosoma mansoni inositol monophosphatase 0.0038 0.0243 0.0264
Echinococcus granulosus insulin receptor 0.0051 0.0368 0.0368
Treponema pallidum quinoline 2-oxidoreductase 0.0029 0.0144 0.0318
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.01 0.0114
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0243
Schistosoma mansoni ap endonuclease 0.002 0.0052 0.0056
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0032 0.0184 0.0558
Echinococcus granulosus transient receptor potential gamma protein 0.0036 0.0224 0.0224
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0066 0.0128
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0311 0.0338
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0079 0.0664 0.1087
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0072 0.0585 0.0585
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0589 0.5866 0.7596
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0189 0.0324
Echinococcus multilocularis g protein coupled receptor 0.0136 0.1236 0.1236
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0036 0.0216 0.0216
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.003 0.0161 0.0285
Echinococcus multilocularis glutamate receptor NMDA 0.0082 0.0687 0.0687
Echinococcus multilocularis g-protein coupled receptor 0.0136 0.1236 0.1236
Plasmodium falciparum phd finger protein, putative 0.003 0.0161 0.0266
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Brugia malayi sulfakinin receptor protein 0.0136 0.1236 0.2024
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Loa Loa (eye worm) hypothetical protein 0.0026 0.0119 0.021
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0085 0.0715 0.2532
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.01 0.024
Loa Loa (eye worm) norepinephrine transporter 0.0251 0.2412 0.4291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0109 0.0221
Schistosoma mansoni lamin 0.0054 0.0406 0.0441
Brugia malayi hypothetical protein 0.0026 0.0119 0.0195
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Onchocerca volvulus 0.0043 0.0287 0.0475
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2586 0.5474
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0036 0.0224 0.034
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0085 0.0715 0.1449
Leishmania major ferric reductase, putative 0.0035 0.0213 0.0261
Echinococcus multilocularis orexin receptor type 2 0.0136 0.1236 0.1236
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0136 0.1236 0.1236
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0012 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0898 0.0976
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0297 0.062
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0099 0.0863 0.0863
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1742 0.3685
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0032 0.0184 0.0558
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0406 0.0721
Onchocerca volvulus 0.0477 0.4722 1
Schistosoma mansoni tyrosine kinase 0.004 0.026 0.0282
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0045 0.0311 0.0311
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0036 0.0216 0.0382
Echinococcus granulosus sodium and chloride dependent glycine 0.0043 0.0287 0.0287
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0189 0.0189
Entamoeba histolytica calmodulin, putative 0.0025 0.0112 0.0258
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0188 0.0188
Giardia lamblia GTOR 0.0047 0.0328 0.1012
Brugia malayi SRC-1 0.004 0.026 0.0426
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0024 0.0094 0.0165
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2946 0.6238
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0116
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0073 0.0601 0.0601
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0073 0.0601 0.1205
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0388 0.0688
Schistosoma mansoni glutamate receptor kainate 0.0168 0.1566 0.1702
Brugia malayi putative neuropeptide receptor NPR1 0.0136 0.1236 0.2024
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0102 0.0898 0.115
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0192 0.1808 0.1808
Schistosoma mansoni transient receptor potential channel 0.0036 0.0224 0.0243
Echinococcus multilocularis g protein coupled receptor 0.0136 0.1236 0.1236
Echinococcus multilocularis dro:myosuppressin receptor 0.0136 0.1236 0.1236
Echinococcus granulosus peptide allatostatin:somatostatin 0.0136 0.1236 0.1236
Loa Loa (eye worm) voltage-dependent calcium channel 0.0055 0.0411 0.073
Echinococcus multilocularis Rac GTPase activating protein 1 0.0077 0.0639 0.0639
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0036 0.0224 0.0224
Leishmania major trypanothione reductase 0.0477 0.4721 0.6109
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0311 0.0338
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0031 0.0171 0.035
Brugia malayi G-protein coupled receptor 0.0136 0.1236 0.2024
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0079 0.0664 0.1615
Schistosoma mansoni neuropeptide F-like receptor 0.0136 0.1236 0.1343
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0032 0.0184 0.0378
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0036 0.0224 0.0275
Echinococcus granulosus CalModulin family member cmd 1 0.0025 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0116
Loa Loa (eye worm) hypothetical protein 0.0071 0.0577 0.1026
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0477 0.4721 1
Echinococcus multilocularis 0.0032 0.0184 0.0184
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0136 0.1236 0.1343
Onchocerca volvulus 0.0136 0.1236 0.2513
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0066 0.0066
Trypanosoma cruzi NADH dehydrogenase, putative 0.0073 0.0601 0.0764
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0192 0.1808 0.1808
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0073 0.0601 0.1264
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0161 0.0266
Onchocerca volvulus 0.0051 0.0376 0.0666
Loa Loa (eye worm) hypothetical protein 0.0052 0.0381 0.0677
Echinococcus granulosus microtubule associated protein 2 0.0716 0.7156 0.7156
Trypanosoma cruzi trypanothione reductase, putative 0.0276 0.2673 0.3452
Schistosoma mansoni ryanodine receptor related 0.0036 0.0224 0.0244
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1646 0.348
Plasmodium falciparum amino acid transporter, putative 0.0043 0.0287 0.0534
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0161 0.0175
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0243 0.03
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0136 0.1236 0.2024
Echinococcus multilocularis glutamate receptor 2 0.012 0.1075 0.1075
Brugia malayi cation channel family protein 0.0036 0.0224 0.0367
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0231 0.0479
Loa Loa (eye worm) hypothetical protein 0.0086 0.0732 0.1302
Schistosoma mansoni transient receptor potential channel 0.0037 0.0227 0.0246
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0276 0.2673 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0276 0.2673 0.5628
Onchocerca volvulus 0.0041 0.027 0.0438
Echinococcus multilocularis musashi 0.0054 0.0406 0.0406
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0243 0.0243
Echinococcus granulosus peregrin 0.003 0.0161 0.0161
Echinococcus granulosus biogenic amine 5HT receptor 0.0388 0.3813 0.3813
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0161 0.0161
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0073 0.0601 0.194
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0032 0.0184 0.0378
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0206 0.0427
Brugia malayi hypothetical protein 0.0136 0.1236 0.2024
Echinococcus granulosus G protein coupled receptor 139 0.0136 0.1236 0.1236
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0036 0.0224 0.0275
Echinococcus multilocularis lamin 0.0054 0.0406 0.0406
Loa Loa (eye worm) hypothetical protein 0.0104 0.0913 0.1624
Loa Loa (eye worm) hypothetical protein 0.0251 0.2412 0.4291
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0066 0.0066
Echinococcus granulosus chromobox protein 1 0.0072 0.059 0.059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0042 0.0078
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0136 0.1236 0.1236
Echinococcus multilocularis hyperpolarization activated cyclic 0.0041 0.0276 0.0276
Leishmania major hypothetical protein, conserved 0.0073 0.0601 0.0764
Loa Loa (eye worm) cytochrome P450 family protein 0.005 0.0364 0.0645
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0287 0.0312
Echinococcus granulosus calmodulin 0.0025 0.0112 0.0112
Echinococcus multilocularis tyrosine protein kinase Blk 0.0036 0.0221 0.0221
Brugia malayi Doublecortin family protein 0.0041 0.027 0.0442
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0287 0.0312
Schistosoma mansoni amine GPCR 0.0136 0.1236 0.1343
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0898 0.1894
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0328 0.0328
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0041 0.0276 0.0489
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0226 0.0226
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0032 0.0184 0.0558
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0111 0.0986 0.0986
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0472 0.0472
Plasmodium vivax thioredoxin reductase, putative 0.0477 0.4721 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.1236 0.1343
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0073 0.0601 0.1205
Loa Loa (eye worm) hypothetical protein 0.0024 0.0094 0.0165
Loa Loa (eye worm) hypothetical protein 0.0098 0.0854 0.1518
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0189 0.0205
Echinococcus granulosus tyrosine kinase 0.0026 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0116
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Schistosoma mansoni glutamate receptor kainate 0.0168 0.1566 0.1702
Loa Loa (eye worm) glutamate receptor 1 0.0168 0.1566 0.2787
Brugia malayi RhoGAP domain containing protein 0.0066 0.0531 0.087
Echinococcus granulosus glutamate NMDA receptor subunit 0.034 0.3319 0.3319
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0077 0.0085
Loa Loa (eye worm) hypothetical protein 0.0067 0.0537 0.0954
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0224 0.0224
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0163 0.1513 0.1947
Echinococcus granulosus ATP binding cassette sub family G 0.0018 0.0037 0.0037
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0031 0.0171 0.0412
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0069 0.0113
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0136 0.1236 0.1236
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0073 0.0601 0.1264
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.0026 0.0044
Echinococcus multilocularis neuropeptide s receptor 0.0613 0.6105 0.6105
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0189 0.0229
Loa Loa (eye worm) hypothetical protein 0.0021 0.0066 0.0116
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0031 0.0171 0.0286
Schistosoma mansoni hypothetical protein 0.005 0.0366 0.0398
Brugia malayi calmodulin 0.0025 0.0112 0.0183
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0066 0.0072
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0061 0.0472 0.165
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0328 0.1002
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0073 0.0601 0.1263
Trypanosoma cruzi cytochrome P450, putative 0.005 0.0364 0.0456
Trypanosoma cruzi calmodulin 0.0025 0.0112 0.0129
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0087 0.0741 0.0741
Loa Loa (eye worm) hypothetical protein 0.0245 0.2355 0.4191
Loa Loa (eye worm) programmed cell death 8 0.0073 0.0601 0.1068
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.01 0.0185
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0032 0.0184 0.0378
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0066 0.0066
Plasmodium vivax calmodulin, putative 0.0025 0.0112 0.016
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0148 0.1364 0.5034
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0189 0.0324
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0134 0.1215 0.1321
Echinococcus multilocularis ATP binding cassette sub family G 0.0018 0.0037 0.0037
Onchocerca volvulus 0.0068 0.055 0.1041
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0276 0.0574
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0243 0.0711
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0036 0.0221 0.0221
Echinococcus multilocularis CalModulin family member (cmd 1) 0.0025 0.0112 0.0112
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0085 0.0715 0.1505
Onchocerca volvulus 0.0136 0.1236 0.2513
Loa Loa (eye worm) doublecortin family protein 0.0041 0.027 0.0478
Leishmania major hypothetical protein, conserved 0.0036 0.0224 0.0275
Chlamydia trachomatis DNA gyrase subunit A 0.0031 0.0171 0.0275
Trichomonas vaginalis xanthine dehydrogenase, putative 0.018 0.1686 0.3566
Echinococcus multilocularis fmrfamide receptor 0.0136 0.1236 0.1236
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0382 0.375 0.6142
Giardia lamblia Glutamate synthase 0.0073 0.0601 0.195
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0073 0.0601 0.1446
Echinococcus granulosus tachykinin peptides receptor 99D 0.0136 0.1236 0.1236
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0224 0.0224
Echinococcus multilocularis sodium and chloride dependent glycine 0.0043 0.0287 0.0287
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0032 0.0184 0.0378
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0073 0.0601 0.0764
Schistosoma mansoni glutamate receptor kainate 0.0168 0.1566 0.1702
Schistosoma mansoni adenoreceptor 0.0136 0.1236 0.1343
Echinococcus multilocularis nmda type glutamate receptor 0.0193 0.182 0.182
Trypanosoma brucei trypanothione reductase 0.0477 0.4721 0.6109
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0073 0.0601 0.2141
Onchocerca volvulus 0.0136 0.1236 0.2513
Loa Loa (eye worm) hypothetical protein 0.0025 0.0109 0.0193
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0231 0.0284
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0243
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0036 0.0224 0.0224
Echinococcus multilocularis serotonin receptor 0.0388 0.3813 0.3813
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0041 0.0276 0.0276
Loa Loa (eye worm) melatonin receptor type 1A 0.0136 0.1236 0.2198
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0149 0.0263
Loa Loa (eye worm) thioredoxin reductase 0.0477 0.4721 0.8403
Onchocerca volvulus 0.0077 0.0642 0.1238
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0085 0.0717 0.2582
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0032 0.0184 0.0558
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0072 0.0585 0.0585
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0073 0.0601 0.1264
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0276 0.2673 0.5628
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0102 0.0898 0.115
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0102 0.0898 0.115
Onchocerca volvulus 0.0024 0.0094 0.006
Echinococcus granulosus sodium leak channel non selective protein 0.0036 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Plasmodium vivax ferrodoxin reductase, putative 0.0073 0.0601 0.1205
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0231 0.0284
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0072 0.0589 0.0964
Echinococcus multilocularis glutamate receptor 2 0.0168 0.1566 0.1566
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0086 0.0732 0.0796
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0034 0.0203 0.063
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0039 0.0253 0.0696
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0043 0.0287 0.0509
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0073 0.0601 0.0601
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0136 0.1236 0.1236
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0066 0.0109
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0073 0.0601 0.1205
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0066 0.0072
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0043 0.0287 0.0287
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0053 0.0396 0.0703
Echinococcus multilocularis dnaJ subfamily B 0.0424 0.4181 0.4181
Echinococcus granulosus neuropeptides capa receptor 0.0136 0.1236 0.1236
Schistosoma mansoni protein kinase 0.0029 0.0149 0.0162
Echinococcus granulosus two pore calcium channel protein 1 0.0036 0.0224 0.0224
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0043 0.0287 0.0287
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0189 0.0388
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0052 0.0098
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0036 0.0224 0.0243
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0073 0.0601 0.1205
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.1236 0.1343
Echinococcus granulosus serotonin receptor 0.0136 0.1236 0.1236
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0036 0.0224 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0266 0.0553
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2586 0.5474
Trypanosoma brucei C-8 sterol isomerase, putative 0.0382 0.375 0.4849
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0029 0.0149 0.0179
Echinococcus multilocularis g protein coupled receptor 0.0136 0.1236 0.1236
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0073 0.0601 0.2097
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0052 0.0099
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0066 0.0116
Loa Loa (eye worm) hypothetical protein 0.0388 0.3813 0.6787
Loa Loa (eye worm) hypothetical protein 0.0024 0.0094 0.0165
Loa Loa (eye worm) hypothetical protein 0.0024 0.0094 0.0165
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0102 0.0898 0.115
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0136 0.1236 0.1236
Loa Loa (eye worm) hypothetical protein 0.0565 0.5618 1
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0052 0.0099
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.052 0.0565
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.01 0.02
Echinococcus multilocularis calmodulin 0.0025 0.0112 0.0112
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2946 0.6238
Echinococcus multilocularis GPCR, family 2 0.0033 0.0188 0.0188
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0898 0.1894
Schistosoma mansoni hypothetical protein 0.0033 0.0188 0.0204
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0012 0.0012
Echinococcus granulosus arachidonate 5 lipoxygenase 0.018 0.1685 0.1685
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0397
Loa Loa (eye worm) glutamate receptor 0.0024 0.0094 0.0165
Echinococcus granulosus voltage dependent calcium channel 0.0055 0.0411 0.0411
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0276 0.2673 0.3452
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.01 0.0167
Toxoplasma gondii endonuclease IV APN 0.0079 0.0664 0.1339
Schistosoma mansoni metabotropic glutamate receptor 0.0024 0.0094 0.0102
Giardia lamblia Kinase, CMGC MAPK 0.0102 0.0898 0.2969
Loa Loa (eye worm) hypothetical protein 0.0092 0.0794 0.1413
Brugia malayi voltage-dependent calcium channel 0.0036 0.0224 0.0367
Echinococcus multilocularis voltage gated potassium channel 0.0045 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0565 0.5618 1
Leishmania major calmodulin, putative 0.0025 0.0112 0.0129
Onchocerca volvulus 0.0036 0.0224 0.034
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0024 0.0094 0.0154
Brugia malayi nuclear hormone receptor 0.0021 0.0066 0.0109
Schistosoma mansoni amine GPCR 0.0136 0.1236 0.1343
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0276 0.0299
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0442 0.4366 0.4744
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0148 0.1364 0.3505
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0032 0.0184 0.0223
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0136 0.1236 0.1343
Echinococcus multilocularis conserved hypothetical protein 0.0716 0.7156 0.7156
Schistosoma mansoni histamine h1 receptor 0.0136 0.1236 0.1343
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0042 0.0078
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.004 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0061 0.0472 0.0838
Schistosoma mansoni hypothetical protein 0.0176 0.1646 0.1788
Echinococcus granulosus neuropeptide receptor 0.0136 0.1236 0.1236
Echinococcus granulosus glutamate synthase 0.0073 0.0601 0.0601
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.005 0.0049
Onchocerca volvulus 0.0041 0.027 0.0438
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0052 0.0051
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0119 0.0176
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0259 0.0538
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0052 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0066 0.0109
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0072 0.0585 0.0585
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0087 0.0741 0.0741
Schistosoma mansoni hypothetical protein 0.0136 0.1236 0.1343
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0136 0.1236 0.1236
Brugia malayi RhoGAP domain containing protein 0.0015 0.0001 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0066 0.0109
Schistosoma mansoni cpg binding protein 0.0031 0.0174 0.0189
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0066 0.0001
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0451 0.0884
Echinococcus granulosus calmodulin 0.0025 0.0111 0.0111
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0036 0.0224 0.0224
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0189 0.0229
Brugia malayi metabotropic glutamate receptor type 2 0.0024 0.0094 0.0154
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0073 0.0601 0.2097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.1236 0.1236
Echinococcus granulosus adenylate cyclase 9 0.0081 0.0677 0.0677
Plasmodium vivax amine transporter, putative 0.0043 0.0287 0.0534
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0136 0.1236 0.1236
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0136 0.1236 0.1343
Leishmania major cytochrome p450-like protein 0.0032 0.0184 0.0223
Toxoplasma gondii cytochrome p450 superfamily protein 0.0032 0.0184 0.0314
Loa Loa (eye worm) voltage-gated potassium channel 0.0036 0.0224 0.0397
Plasmodium vivax DNA gyrase subunit A, putative 0.0031 0.0171 0.0286
Trypanosoma brucei NADH dehydrogenase 0.0073 0.0601 0.0764
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0276 0.2673 1
Chlamydia trachomatis glutamine binding protein 0.0039 0.0253 0.0594
Echinococcus granulosus biogenic amine 5HT receptor 0.0916 0.9203 0.9203
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0328 0.041
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0041 0.0276 0.0276
Trypanosoma cruzi DNA topoisomerase II, putative 0.0137 0.1252 0.1609
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0097
Loa Loa (eye worm) hypothetical protein 0.0043 0.0287 0.0509
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0287 0.0534
Loa Loa (eye worm) hypothetical protein 0.0043 0.0287 0.0509
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0024 0.0094 0.0165
Echinococcus multilocularis G-protein coupled receptor, putative 0.0136 0.1236 0.1236
Loa Loa (eye worm) hypothetical protein 0.0136 0.1236 0.2198
Onchocerca volvulus 0.0251 0.2412 0.5038
Echinococcus multilocularis glutamate synthase 0.0073 0.0601 0.0601
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0136 0.1236 0.1343
Echinococcus multilocularis sodium leak channel non selective protein 0.0036 0.0224 0.0224
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0035 0.0213 0.0261
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0136 0.1236 0.1236
Trypanosoma cruzi calmodulin, putative 0.0025 0.0112 0.0129
Trypanosoma brucei DNA topoisomerase ii 0.0163 0.1513 0.1947
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0363 0.0595
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0038 0.0237 0.0462
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0472 0.0472
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0268 0.2586 0.4602
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2946 0.6238
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0224 0.0224
Echinococcus granulosus survival motor neuron protein 1 0.0245 0.2355 0.2355
Echinococcus granulosus L aminoadipate semialdehyde 0.0086 0.0732 0.0732
Toxoplasma gondii transporter, cation channel family protein 0.0036 0.0224 0.04
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0045 0.0311 0.0311
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0266 0.0553
Echinococcus granulosus neuropeptide receptor A26 0.0613 0.6105 0.6105
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0181 0.1697 0.3587
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0073 0.0601 0.0764
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0181 0.1697 0.3587
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0061 0.0472 0.0989

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) = 8.4 uM Antiproliferative activity against human A549 cells by sulforhodamine B assay ChEMBL. 25770782
IC50 (functional) = 0.89 ug ml-1 Cytotoxicity against human A172 cells after 6 days ChEMBL. 18044843
IC50 (functional) = 0.49 umol/ml Growth inhibition of human A172 cells after 6 days ChEMBL. 18044843

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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