Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | pax transcription factor protein 2 | 0.0234 | 0.4133 | 0.4133 |
Onchocerca volvulus | 0.0234 | 0.4133 | 1 | |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0482 | 0.9502 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0505 | 1 | 1 |
Brugia malayi | Pax transcription factor protein 2 | 0.0234 | 0.4133 | 0.4133 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0505 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0505 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.