Detailed information for compound 505347

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 428.952 | Formula: C24H29ClN2O3
  • H donors: 1 H acceptors: 2 LogP: 5.62 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cc(C)c(c(c1)C)C(=O)N(C(C)(C)C)NC(=O)c1ccc2c(c1Cl)CCCO2
  • InChi: 1S/C24H29ClN2O3/c1-14-12-15(2)20(16(3)13-14)23(29)27(24(4,5)6)26-22(28)18-9-10-19-17(21(18)25)8-7-11-30-19/h9-10,12-13H,7-8,11H2,1-6H3,(H,26,28)
  • InChiKey: VVRJZYATRXPBRB-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0147 0.1899 0.2851
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0492 0.0714
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0052 0.0492 0.0562
Loa Loa (eye worm) programmed cell death 8 0.0021 0.0031 0.0035
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0492 0.0714
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0552 0.1057
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0147 0.1899 0.2851
Leishmania major hypothetical protein, conserved 0.0056 0.0552 0.0811
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0021 0.0031 0.0009
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0021 0.0031 0.0045
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.019 0.0325
Plasmodium falciparum ferrodoxin reductase-like protein 0.0021 0.0031 0.0019
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0021 0.0031 0.0035
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0147 0.1899 0.4062
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0082 0.0092
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0225 0.3061 0.6055
Schistosoma mansoni rab6-interacting 0.0021 0.0032 0.0024
Echinococcus granulosus methyl CpG binding domain protein 2 0.0033 0.0206 0.0281
Echinococcus granulosus neuropeptide FF receptor 2 0.0147 0.1899 0.2851
Schistosoma mansoni adenoreceptor 0.0147 0.1899 0.4062
Entamoeba histolytica iron-containing superoxide dismutase 0.0064 0.0671 0.4035
Giardia lamblia hypothetical protein 0.0056 0.0552 0.6034
Leishmania major superoxide dismutase, putative 0.0037 0.0258 0.0379
Loa Loa (eye worm) hypothetical protein 0.0306 0.4263 0.4871
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0021 0.0031 0.0045
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Echinococcus granulosus dro:myosuppressin receptor 0.0147 0.1899 0.2851
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0028 0.0137 0.0116
Echinococcus granulosus biogenic amine 5HT receptor 0.0147 0.1899 0.2851
Echinococcus granulosus neuropeptides capa receptor 0.0147 0.1899 0.2851
Loa Loa (eye worm) hypothetical protein 0.0074 0.0819 0.0936
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0147 0.1899 0.217
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0127 0.1607 0.2407
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0552 0.0811
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0225 0.3061 0.4501
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0021 0.0031 0.0007
Brugia malayi Dopamine receptor 0.0147 0.1899 0.217
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0077 0.0099
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0077 0.0152
Trypanosoma cruzi superoxide dismutase, putative 0.0037 0.0258 0.0379
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0021 0.0031 0.0045
Loa Loa (eye worm) PHD-finger family protein 0.004 0.0309 0.0353
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0147 0.1899 0.4062
Brugia malayi hypothetical protein 0.0147 0.1899 0.217
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0028 0.0137 0.0231
Echinococcus granulosus thioredoxin glutathione reductase 0.023 0.3134 0.4725
Trypanosoma cruzi superoxide dismutase, putative 0.0037 0.0258 0.0379
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0588 0.1128
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0552 0.1057
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0552 0.1057
Onchocerca volvulus 0.0147 0.1899 0.1874
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0147 0.1899 0.4062
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0024 0.0077 0.0092
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0056 0.0552 0.0805
Brugia malayi Steroid receptor seven-up type 2 0.0052 0.0492 0.0562
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0052 0.0492 0.1017
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0147 0.1899 0.4062
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0031 0.0009
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0532
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Onchocerca volvulus 0.0035 0.0232 0.0202
Onchocerca volvulus 0.0147 0.1899 0.1874
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.1573 0.2356
Brugia malayi phosphofructokinase 0.0105 0.1274 0.1456
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0094
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0246 0.0225
Loa Loa (eye worm) hypothetical protein 0.0146 0.1888 0.2157
Brugia malayi larval opioid receptor 0.0147 0.1899 0.217
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0052 0.0492 0.1017
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0024 0.0077 0.0088
Echinococcus multilocularis neuropeptide Y receptor 0.0147 0.1899 0.2851
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0232 0.0265
Plasmodium falciparum thioredoxin reductase 0.023 0.3134 0.6201
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0021 0.0031 0.0007
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0056 0.0552 0.0805
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0147 0.1899 0.1874
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0359 0.504 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0032 0.0037
Schistosoma mansoni phospholipase A-2-activating protein 0.0023 0.0064 0.0093
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0056 0.0552 0.063
Giardia lamblia NADH oxidase lateral transfer candidate 0.008 0.0901 1
Echinococcus multilocularis G protein coupled receptor 139 0.0147 0.1899 0.2851
Echinococcus granulosus rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0147 0.1899 0.2851
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Schistosoma mansoni neuropeptide receptor 0.0147 0.1899 0.4062
Echinococcus granulosus intestinal type alkaline phosphatase 0.0314 0.4377 0.6612
Wolbachia endosymbiont of Brugia malayi superoxide dismutase, SodA 0.0064 0.0671 0.1278
Brugia malayi 6-phosphofructokinase 0.0105 0.1274 0.1456
Trypanosoma brucei protein kinase, putative 0.0049 0.0447 0.0657
Leishmania major hypothetical protein, conserved 0.0021 0.0031 0.0045
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0024 0.0077 0.0113
Leishmania major hypothetical protein, conserved 0.0035 0.0233 0.0342
Giardia lamblia Thioredoxin reductase 0.0021 0.0031 0.0106
Echinococcus multilocularis RUN 0.0021 0.0032 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0052 0.0492 0.0562
Entamoeba histolytica disulphide oxidoreductase, putative 0.0021 0.0031 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0552 0.0811
Schistosoma mansoni neuropeptide receptor 0.0147 0.1899 0.4062
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0077 0.0152
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0031 0.0009
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0082 0.0092
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0021 0.0031 0.0045
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0082 0.0131
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0225 0.3061 0.6055
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.008 0.0901 0.1324
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0624 0.0713
Brugia malayi hypothetical protein 0.0039 0.0293 0.0335
Echinococcus granulosus acetylcholinesterase 0.0067 0.0716 0.1055
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0131 0.0218
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0225 0.0204
Loa Loa (eye worm) hypothetical protein 0.0055 0.0532 0.0608
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.008 0.0901 0.1324
Schistosoma mansoni bromodomain containing protein 0.0123 0.1535 0.3275
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0056 0.0552 0.1147
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0322 0.0639
Onchocerca volvulus 0.0147 0.1899 0.1874
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0056 0.0552 0.063
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.1274 0.1874
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0413 0.0848
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0322 0.0474
Schistosoma mansoni neuropeptide receptor 0.0147 0.1899 0.4062
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.0447 0.0657
Trichomonas vaginalis superoxide dismutase [mn], putative 0.0064 0.0671 0.0651
Schistosoma mansoni single-minded 0.0047 0.0413 0.0848
Brugia malayi follicle stimulating hormone receptor 0.0147 0.1899 0.217
Leishmania major guanine deaminase, putative 0.0129 0.1632 0.24
Schistosoma mansoni hypothetical protein 0.0147 0.1899 0.4062
Onchocerca volvulus 0.0147 0.1899 0.1874
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Brugia malayi ecdysone receptor 0.0025 0.0082 0.0094
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0077 0.0152
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0031 0.0019
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0077 0.0152
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0082 0.0092
Brugia malayi hypothetical protein 0.0147 0.1899 0.217
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0082 0.0052
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0121 0.1514 0.2966
Echinococcus granulosus rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Loa Loa (eye worm) fli-1 protein 0.0212 0.2867 0.3276
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.012 0.1502 0.3204
Schistosoma mansoni hypothetical protein 0.0147 0.1899 0.4062
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.008 0.0901 0.1787
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.008 0.0901 0.1029
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0021 0.0031 0.0045
Plasmodium vivax importin-beta 2, putative 0.0028 0.0131 0.0218
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0025 0.0082 0.0092
Trypanosoma brucei guanine deaminase, putative 0.0129 0.1632 0.24
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0314 0.4377 0.6612
Onchocerca volvulus Bile acid receptor homolog 0.0052 0.0492 0.0462
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0028 0.0137 0.0857
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0021 0.0031 0.0014
Schistosoma mansoni amine GPCR 0.0147 0.1899 0.4062
Loa Loa (eye worm) hypothetical protein 0.0056 0.0552 0.063
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0552 0.1057
Onchocerca volvulus 0.0021 0.0032 0.0002
Echinococcus multilocularis fmrfamide receptor 0.0147 0.1899 0.2851
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0032 0.0017
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0147 0.1899 0.2851
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1899 0.4062
Schistosoma mansoni hypothetical protein 0.0298 0.414 0.891
Brugia malayi hypothetical protein 0.0147 0.1899 0.217
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0021 0.0031 0.0061
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Echinococcus multilocularis ecdysone induced protein 78C 0.0052 0.0492 0.0714
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0024 0.0077 0.0111
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.008 0.0901 0.1736
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0137 0.0213
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0532
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0024 0.0077 0.0152
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.008 0.0901 0.1324
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0082 0.0131
Onchocerca volvulus 0.0052 0.0492 0.0462
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0077 0.0152
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0056 0.0552 0.1147
Echinococcus multilocularis neuropeptide receptor 0.0147 0.1899 0.2851
Schistosoma mansoni dihydropteridine reductase 0.0024 0.0077 0.012
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.1274 0.1255
Echinococcus granulosus allatostatin A receptor 0.0147 0.1899 0.2851
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0056 0.0552 0.1147
Schistosoma mansoni hypothetical protein 0.0021 0.0032 0.0024
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0137 0.0231
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.008 0.0901 0.1324
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.0447 0.0645
Leishmania major NADH dehydrogenase, putative 0.0021 0.0031 0.0045
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.1274 0.1456
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0052 0.0492 0.0714
Schistosoma mansoni hypothetical protein 0.0332 0.4644 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0077 0.0152
Echinococcus granulosus fetal alzheimer antigen falz 0.0044 0.0364 0.0521
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0246 0.0361
Trypanosoma brucei iron superoxide dismutase A, mitochondrial 0.0064 0.0671 0.0987
Plasmodium falciparum thioredoxin reductase 0.008 0.0901 0.1752
Echinococcus multilocularis dro:myosuppressin receptor 0.0147 0.1899 0.2851
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0322 0.0474
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.1274 0.1255
Trypanosoma cruzi PAB1-binding protein , putative 0.0055 0.0532 0.0783
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0094
Echinococcus granulosus geminin 0.0332 0.4644 0.7018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0052 0.0492 0.0562
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0021 0.0031 0.0019
Schistosoma mansoni steroid hormone receptor ad4bp 0.0052 0.0492 0.1017
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0552 0.0811
Schistosoma mansoni alpha-1 adrenergic receptor 0.0147 0.1899 0.4062
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0225 0.3061 0.4614
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0246 0.0225
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0052 0.0492 0.0562
Loa Loa (eye worm) hypothetical protein 0.0064 0.0671 0.0767
Echinococcus multilocularis neuropeptides capa receptor 0.0147 0.1899 0.2851
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0052 0.0492 0.0562
Echinococcus multilocularis zinc finger protein 0.0038 0.0279 0.0391
Toxoplasma gondii NADPH-glutathione reductase 0.008 0.0901 0.1752
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0021 0.0031 0.0019
Trichomonas vaginalis mercuric reductase, putative 0.008 0.0901 0.0881
Echinococcus multilocularis orexin receptor type 2 0.0147 0.1899 0.2851
Toxoplasma gondii superoxide dismutase SOD3 0.0064 0.0671 0.1295
Brugia malayi nuclear receptor NHR-88 0.0025 0.0082 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0052 0.0492 0.0562
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0052 0.0031
Plasmodium falciparum enoyl-acyl carrier reductase 0.0359 0.504 1
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0225 0.3061 0.6574
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0031 0.0045
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0084 0.0965 0.1432
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0052 0.0492 0.0562
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0021 0.0031
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0552 0.1057
Loa Loa (eye worm) hypothetical protein 0.0032 0.0189 0.0215
Brugia malayi WD domain containing protein 0.0035 0.0233 0.0266
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0492 0.1017
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0225 0.3061 0.4501
Loa Loa (eye worm) hypothetical protein 0.0052 0.0492 0.0562
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.1573 0.2356
Mycobacterium ulcerans hydroxydechloroatrazine ethylaminohydrolase 0.0129 0.1632 0.3238
Plasmodium vivax ataxin-2 like protein, putative 0.0055 0.0532 0.1018
Brugia malayi RNA binding protein 0.0061 0.0624 0.0713
Trichomonas vaginalis superoxide dismutase [fe], putative 0.0064 0.0671 0.0651
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0552 0.1057
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0147 0.1899 0.4062
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0322 0.0301
Toxoplasma gondii LsmAD domain-containing protein 0.0055 0.0532 0.1018
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0532
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0532
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0232 0.032
Schistosoma mansoni biogenic amine (5HT) receptor 0.0147 0.1899 0.4062
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0024 0.0077 0.0099
Onchocerca volvulus 0.0147 0.1899 0.1874
Echinococcus multilocularis geminin 0.0332 0.4644 0.7018
Loa Loa (eye worm) acetylcholinesterase 1 0.0067 0.0716 0.0818
Loa Loa (eye worm) RNA binding protein 0.0061 0.0624 0.0713
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.1274 0.7778
Plasmodium falciparum superoxide dismutase [Fe] 0.0064 0.0671 0.1295
Brugia malayi Carboxylesterase family protein 0.0067 0.0716 0.0818
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.0447 0.0657
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Echinococcus multilocularis acetylcholinesterase 0.0067 0.0716 0.1055
Onchocerca volvulus 0.0147 0.1899 0.1874
Brugia malayi Dopamine receptor protein 2 0.0147 0.1899 0.217
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0021 0.0031 0.0061
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0298 0.414 0.4731
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0021 0.0031 0.0058
Loa Loa (eye worm) hypothetical protein 0.012 0.1502 0.1717
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0021 0.0031 0.0014
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.007 0.0754 0.0862
Echinococcus granulosus FTZ F1 alpha 0.0052 0.0492 0.0714
Echinococcus granulosus 7tm_1 domain containing protein 0.0147 0.1899 0.2851
Brugia malayi Carboxylesterase family protein 0.0067 0.0716 0.0818
Schistosoma mansoni amine GPCR 0.0147 0.1899 0.4062
Trypanosoma brucei iron superoxide dismutase C, mitochondrial 0.0037 0.0258 0.0379
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Loa Loa (eye worm) hypothetical protein 0.0052 0.0492 0.0562
Schistosoma mansoni zinc finger protein 0.003 0.0156 0.0291
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0024 0.0077 0.0092
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0532
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0031 0.0019
Echinococcus multilocularis neuropeptide receptor 0.0147 0.1899 0.2851
Schistosoma mansoni coup transcription factor 0.0052 0.0492 0.1017
Loa Loa (eye worm) hypothetical protein 0.0079 0.0887 0.1014
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0052 0.0492 0.0562
Loa Loa (eye worm) hypothetical protein 0.0028 0.0131 0.0149
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0032 0.0017
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.1274 0.1255
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0314 0.4377 0.6612
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Trichomonas vaginalis iron superoxide dismutase A, putative 0.0064 0.0671 0.0651
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0056 0.0552 0.1147
Schistosoma mansoni amine GPCR 0.0147 0.1899 0.4062
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0077 0.0152
Entamoeba histolytica hypothetical protein 0.0039 0.0293 0.1687
Toxoplasma gondii superoxide dismutase 0.0064 0.0671 0.1295
Loa Loa (eye worm) hypothetical protein 0.0056 0.0552 0.063
Brugia malayi Tachykinin-like peptides receptor 99D 0.0147 0.1899 0.217
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0077 0.0152
Schistosoma mansoni hypothetical protein 0.003 0.0156 0.0291
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.008 0.0901 0.1742
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Echinococcus granulosus g-protein coupled receptor 0.0147 0.1899 0.2851
Loa Loa (eye worm) hypothetical protein 0.0052 0.0492 0.0562
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0024 0.0077 0.0111
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1105 0.2344
Leishmania major trypanothione reductase 0.023 0.3134 0.4608
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.008 0.0901 0.1752
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0147 0.1899 0.4062
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0082 0.0092
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0137 0.0116
Loa Loa (eye worm) hypothetical protein 0.0052 0.0492 0.0562
Trypanosoma cruzi trypanothione reductase, putative 0.008 0.0901 0.1324
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0246 0.0487
Schistosoma mansoni hypothetical protein 0.0332 0.4644 1
Echinococcus granulosus hypothetical protein 0.0147 0.1899 0.2851
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0077 0.0152
Leishmania major hypothetical protein, conserved 0.0021 0.0031 0.0045
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0147 0.1899 0.217
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0056 0.0552 0.0811
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0052 0.0492 0.0562
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1105 0.2344
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0246 0.0361
Trichomonas vaginalis protein ssnA, putative 0.0129 0.1632 0.1614
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Loa Loa (eye worm) hypothetical protein 0.0052 0.0492 0.0562
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0293 0.0412
Plasmodium falciparum polyubiquitin binding protein, putative 0.0035 0.0233 0.0421
Trypanosoma cruzi iron superoxide dismutase, putative 0.0064 0.0671 0.0987
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0024 0.0077 0.0152
Schistosoma mansoni glutamate synthase 0.0021 0.0031 0.002
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0082 0.0131
Onchocerca volvulus 0.0147 0.1899 0.1874
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.0447 0.4836
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0552 0.0811
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1899 0.4062
Echinococcus granulosus phospholipase A 2 activating protein 0.0035 0.0233 0.0321
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0021 0.0031 0.0009
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0067 0.0716 0.1503
Onchocerca volvulus 0.0024 0.0077 0.0046
Brugia malayi PAS domain containing protein 0.0047 0.0413 0.0472
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0077 0.0152
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.023 0.3134 0.6197
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0552 0.1057
Echinococcus granulosus rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Trypanosoma cruzi superoxide dismutase, putative 0.0037 0.0258 0.0379
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0056 0.0552 0.0805
Plasmodium falciparum phosphodiesterase gamma, putative 0.0056 0.0552 0.1057
Brugia malayi nuclear receptor NHR-67 0.0025 0.0082 0.0094
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0492 0.0714
Loa Loa (eye worm) hypothetical protein 0.0028 0.0126 0.0144
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0147 0.1899 0.2851
Onchocerca volvulus 0.0146 0.1888 0.1863
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.018 0.2384 0.4701
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0077 0.0152
Echinococcus multilocularis manganese superoxide dismutase 0.0064 0.0671 0.0986
Echinococcus multilocularis g protein coupled receptor 0.0147 0.1899 0.2851
Plasmodium vivax SET domain protein, putative 0.0087 0.1012 0.1974
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.018 0.2384 0.4698
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0025 0.0082 0.0092
Echinococcus granulosus neuropeptides capa receptor 0.0147 0.1899 0.2851
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0322 0.0474
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0021 0.0031 0.0014
Schistosoma mansoni neuropeptide F-like receptor 0.0147 0.1899 0.4062
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0052 0.0492 0.0562
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0624 0.0713
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0094
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0021 0.0031 0.0007
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1105 0.2344
Trichomonas vaginalis protein ssnA, putative 0.0129 0.1632 0.1614
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0052 0.0492 0.0714
Loa Loa (eye worm) DR-78 0.0025 0.0082 0.0094
Mycobacterium tuberculosis Superoxide dismutase [FE] SodA 0.0064 0.0671 0.1284
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.0447 0.0657
Trypanosoma brucei hypothetical protein, conserved 0.0056 0.0552 0.0811
Entamoeba histolytica hypothetical protein 0.0023 0.0052 0.0193
Brugia malayi hypothetical protein 0.0147 0.1899 0.217
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0131 0.0166
Mycobacterium tuberculosis Probable dehydrogenase 0.0121 0.1514 0.2966
Giardia lamblia DINP protein human, muc B family 0.0021 0.0027 0.0066
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0552 0.1057
Plasmodium falciparum superoxide dismutase [Fe] 0.0037 0.0258 0.0471
Brugia malayi Pre-SET motif family protein 0.0609 0.8752 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.008 0.0901 0.1324
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0052 0.0492 0.0714
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0021 0.0031 0.0019
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0624 0.1304
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0056 0.0552 0.0805
Echinococcus granulosus neuropeptide s receptor 0.0147 0.1899 0.2851
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0147 0.1899 0.4062
Trypanosoma cruzi NADH dehydrogenase, putative 0.0021 0.0031 0.0045
Loa Loa (eye worm) hypothetical protein 0.0158 0.2055 0.2348
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0147 0.1899 0.2851
Trichomonas vaginalis superoxide dismutase, putative 0.0064 0.0671 0.0651
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.008 0.0901 0.1736
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0147 0.1899 0.2851
Leishmania major acetoin dehydrogenase e3 component-like protein 0.008 0.0901 0.1324
Brugia malayi hypothetical protein 0.0147 0.1899 0.217
Loa Loa (eye worm) hypothetical protein 0.0052 0.0492 0.0562
Brugia malayi Cytochrome P450 family protein 0.0029 0.0148 0.0169
Plasmodium vivax phosphodiesterase gamma, putative 0.0056 0.0552 0.1057
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0126 0.0159
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0175 0.0257
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0532
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Brugia malayi hypothetical protein 0.0147 0.1899 0.217
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0056 0.0552 0.063
Echinococcus multilocularis neuropeptide Y receptor 0.0147 0.1899 0.2851
Echinococcus granulosus orexin receptor type 2 0.0147 0.1899 0.2851
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0056 0.0552 0.0805
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0052 0.0031
Echinococcus granulosus g protein coupled receptor 0.0147 0.1899 0.2851
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0359 0.504 1
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0811
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.1105 0.1645
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0447 0.0426
Brugia malayi hypothetical protein 0.0028 0.0126 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0322 0.0474
Brugia malayi MAP kinase sur-1 0.0049 0.0447 0.051
Loa Loa (eye worm) hypothetical protein 0.0038 0.0273 0.0312
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0056 0.0552 0.063
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0147 0.1899 0.2851
Trypanosoma brucei iron superoxide dismutase 0.0064 0.0671 0.0987
Leishmania major iron superoxide dismutase, putative 0.0064 0.0671 0.0987
Echinococcus granulosus g protein coupled receptor 0.0147 0.1899 0.2851
Echinococcus granulosus rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0147 0.1899 0.2851
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0024 0.0077 0.0152
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0082 0.0094
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0021 0.0031 0.0014
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0246 0.034
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0052 0.0492 0.0562
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0147 0.1899 0.4062
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0225 0.3061 0.4614
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0056 0.0552 0.0805
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0087 0.1012 0.1504
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1899 0.4062
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.008 0.0901 0.1324
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0147 0.1899 0.217
Echinococcus granulosus importin subunit beta 1 0.0028 0.0131 0.0166
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0322 0.0474
Schistosoma mansoni thyroid hormone receptor 0.0177 0.2349 0.5034
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0478 0.68 1
Echinococcus granulosus neuropeptide Y receptor 0.0147 0.1899 0.2851
Echinococcus multilocularis thioredoxin glutathione reductase 0.023 0.3134 0.4725
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0492 0.0714
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0359 0.504 1
Echinococcus granulosus tm gpcr rhodopsin 0.0147 0.1899 0.2851
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0052 0.0492 0.0562
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0147 0.1899 0.4062
Echinococcus multilocularis thyroid hormone receptor alpha 0.0177 0.2349 0.3533
Schistosoma mansoni hypothetical protein 0.0038 0.0273 0.0545
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0137 0.0116
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0322 0.0301
Treponema pallidum NADH oxidase 0.008 0.0901 0.6996
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0359 0.504 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0147 0.1899 0.4062
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0021 0.0031
Loa Loa (eye worm) carboxylesterase 0.0067 0.0716 0.0818
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0552 0.1057
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0024 0.0077 0.0113
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0447 0.0657
Brugia malayi tailless protein 0.0025 0.0082 0.0094
Onchocerca volvulus 0.0147 0.1899 0.1874
Leishmania major hypothetical protein, conserved 0.0056 0.0552 0.0811
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Trichomonas vaginalis set domain proteins, putative 0.0693 1 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0147 0.1899 0.2851
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.1105 0.1645
Schistosoma mansoni hypothetical protein 0.0147 0.1899 0.4062
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0052 0.0492 0.1017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0052 0.0492 0.0714
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0037 0.026 0.0298
Brugia malayi hypoxia-induced factor 1 0.0145 0.1874 0.2141
Brugia malayi nuclear hormone receptor 0.0025 0.0082 0.0094
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0033 0.0206 0.0281
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0147 0.1899 0.2851
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0056 0.0552 0.0532
Onchocerca volvulus 0.0021 0.0032 0.0002
Schistosoma mansoni opsin-like receptor 0.0147 0.1899 0.4062
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Brugia malayi G protein-coupled receptor 0.0147 0.1899 0.217
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.1274 0.7778
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.018 0.2384 0.4701
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1899 0.4062
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.008 0.0901 0.1752
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0094
Onchocerca volvulus 0.0025 0.0082 0.0052
Leishmania major importin beta-1 subunit, putative 0.0023 0.0052 0.0077
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0077 0.0088
Echinococcus granulosus snurportin 1 0.0298 0.414 0.6253
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.007 0.0749 0.1105
Plasmodium falciparum phosphodiesterase delta, putative 0.0056 0.0552 0.1057
Loa Loa (eye worm) hypothetical protein 0.0056 0.0552 0.063
Echinococcus granulosus g protein coupled receptor 0.0147 0.1899 0.2851
Echinococcus granulosus carboxylesterase 5A 0.0067 0.0716 0.1055
Loa Loa (eye worm) hypothetical protein 0.0067 0.0716 0.0818
Echinococcus granulosus alkaline phosphatase 0.0314 0.4377 0.6612
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0021 0.0031 0.0019
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0056 0.0552 0.0811
Echinococcus granulosus tm gpcr rhodopsin 0.0147 0.1899 0.2851
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0624 0.1304
Schistosoma mansoni voltage-gated potassium channel 0.004 0.031 0.0625
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0056 0.0552 0.1147
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.1274 0.7778
Echinococcus granulosus G protein coupled receptor 139 0.0147 0.1899 0.2851
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0056 0.0552 0.0811
Loa Loa (eye worm) bromodomain containing protein 0.0034 0.0224 0.0256
Schistosoma mansoni inositol monophosphatase 0.0036 0.0246 0.0485
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0082 0.0094
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0077 0.0152
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0031 0.0045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1899 0.4062
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0021 0.0031 0.0014
Brugia malayi Bromodomain containing protein 0.0074 0.0817 0.0934
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0082 0.0092
Brugia malayi glutamate synthase 0.0021 0.0031 0.0035
Brugia malayi nuclear hormone receptor 0.0052 0.0492 0.0562
Loa Loa (eye worm) hypoxia-induced factor 1 0.0145 0.1874 0.2141
Brugia malayi photoreceptor-specific nuclear receptor 0.0052 0.0492 0.0562
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0082 0.0094
Echinococcus multilocularis serotonin receptor 0.0147 0.1899 0.2851
Schistosoma mansoni sulfide quinone reductase 0.0021 0.0031 0.002
Brugia malayi RNA, U transporter 1 0.0079 0.0895 0.1022
Trichomonas vaginalis hypothetical protein 0.0359 0.504 0.503
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0077 0.0152
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0532
Schistosoma mansoni neuropeptide F-like receptor 0.0147 0.1899 0.4062
Brugia malayi hypothetical protein 0.0118 0.1461 0.1669
Loa Loa (eye worm) glutathione reductase 0.023 0.3134 0.3581
Mycobacterium ulcerans hypothetical protein 0.0021 0.0031 0.0061
Echinococcus multilocularis g protein coupled receptor 0.0147 0.1899 0.2851
Echinococcus granulosus neuropeptide receptor A26 0.0147 0.1899 0.2851
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0021 0.0031 0.0058
Echinococcus multilocularis fmrfamide receptor 0.0147 0.1899 0.2851
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0024 0.0077 0.0084
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0021 0.0031 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1899 0.4062
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0031 0.0045
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0082 0.0092
Schistosoma mansoni methyl-cpg binding protein mbd 0.0033 0.0206 0.0401
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Onchocerca volvulus 0.0147 0.1899 0.1874
Toxoplasma gondii superoxide dismutase SOD2 0.0064 0.0671 0.1295
Echinococcus multilocularis somatostatin receptor 0.0147 0.1899 0.2851
Brugia malayi 6-phosphofructokinase 0.0105 0.1274 0.1456
Trypanosoma brucei PAB1-binding protein , putative 0.0055 0.0532 0.0783
Giardia lamblia Glutamate synthase 0.0021 0.0031 0.0106
Brugia malayi hypothetical protein 0.0158 0.2055 0.2348
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0031 0.0009
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0077 0.0152
Chlamydia trachomatis superoxide dismutase 0.0064 0.0671 0.1278
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0552 0.1057
Brugia malayi Doublecortin family protein 0.0021 0.0032 0.0037
Leishmania major GTP-binding protein, putative 0.0021 0.0021 0.0031
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0094
Onchocerca volvulus 0.0147 0.1899 0.1874
Onchocerca volvulus 0.0147 0.1899 0.1874
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0121 0.1514 0.2966
Loa Loa (eye worm) hypothetical protein 0.0024 0.0077 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0552 0.0532
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.0447 0.0645
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0532
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0147 0.1899 0.2851
Brugia malayi neuropeptide F receptor 0.0147 0.1899 0.217
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0087 0.1012 0.2143
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0322 0.0474
Brugia malayi glutathione reductase 0.023 0.3134 0.3581
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0225 0.3061 0.4614
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0246 0.0361
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0052 0.0492 0.0714
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0147 0.1899 0.217
Trypanosoma brucei NADH dehydrogenase 0.0021 0.0031 0.0045
Toxoplasma gondii 6-phosphofructokinase 0.0028 0.0137 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0552 0.0532
Mycobacterium ulcerans dehydrogenase 0.0021 0.0031 0.0061
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0121 0.1514 0.2966
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0225 0.3061 0.3497
Trypanosoma cruzi NADH dehydrogenase, putative 0.0021 0.0031 0.0045
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0059 0.0586 0.067
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0147 0.1899 0.2851
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0056 0.0552 0.1057
Trypanosoma brucei oxidoreductase-like protein 0.0024 0.0077 0.0113
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0552 0.1057
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0052 0.0492 0.0562
Leishmania major iron superoxide dismutase, putative 0.0064 0.0671 0.0987
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0056 0.0552 0.1147
Loa Loa (eye worm) WD domain-containing protein 0.0023 0.0064 0.0073
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0322 0.0474
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Schistosoma mansoni retinoic acid receptor RXR 0.0052 0.0492 0.1017
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0024 0.0077 0.0152
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0147 0.1899 0.2851
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0056 0.0552 0.0811
Brugia malayi Inositol-1 0.0036 0.0246 0.0281
Echinococcus granulosus 6 phosphofructokinase 0.0105 0.1274 0.1902
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Leishmania major cAMP-specific phosphodiesterase, putative 0.0478 0.68 1
Trypanosoma cruzi trypanothione reductase, putative 0.023 0.3134 0.4608
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Entamoeba histolytica hypothetical protein 0.0039 0.0293 0.1687
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0273 0.0312
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0322 0.0474
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0024 0.0077 0.0111
Loa Loa (eye worm) hypothetical protein 0.0137 0.1749 0.1999
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0021 0.0024
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0059 0.0586 0.067
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0137 0.0231
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0031 0.0009
Loa Loa (eye worm) hypothetical protein 0.0055 0.0531 0.0607
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1899 0.4062
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0127 0.1607 0.2407
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0811
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0246 0.034
Echinococcus granulosus somatostatin receptor 0.0147 0.1899 0.2851
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0314 0.4377 0.6612
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.008 0.0901 0.1324
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.0447 0.0645
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0447 0.0426
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0087 0.1012 0.2143
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0032 0.0037
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0056 0.0552 0.0805
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0021 0.0031 0.0014
Loa Loa (eye worm) neuropeptide F receptor 0.0147 0.1899 0.217
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0052 0.0492 0.0562
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0024 0.0077 0.0152
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0024 0.0077 0.0111
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0021 0.0031
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0137 0.0116
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0077 0.0099
Schistosoma mansoni myosin xvIII 0.0147 0.1899 0.4062
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.008 0.0901 0.1324
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0094
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.026 0.0363
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0021 0.0031 0.0007
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0552 0.1057
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0044 0.0364 0.0742
Toxoplasma gondii PUL domain-containing protein 0.0035 0.0233 0.0421
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Loa Loa (eye worm) inositol-1 0.0036 0.0246 0.0281
Echinococcus multilocularis g protein coupled receptor 0.0147 0.1899 0.2851
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Onchocerca volvulus Protein ultraspiracle homolog 0.0052 0.0492 0.0462
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.1057
Echinococcus multilocularis serotonin receptor 0.0147 0.1899 0.2851
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0531 0.0607
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0021 0.0031 0.0061
Brugia malayi Ets-domain containing protein 0.007 0.0754 0.0862
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0024 0.0077 0.0099
Schistosoma mansoni biogenic amine receptor 0.0147 0.1899 0.4062
Loa Loa (eye worm) oxidoreductase 0.0024 0.0077 0.0088
Loa Loa (eye worm) hypothetical protein 0.0083 0.0942 0.1077
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0082 0.0092
Echinococcus granulosus acetylcholinesterase 0.0067 0.0716 0.1055
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0077 0.0152
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0056 0.0552 0.6034
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0056 0.0552 0.063
Brugia malayi GnHR receptor homolog 0.0147 0.1899 0.217
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0322 0.0474
Brugia malayi hypothetical protein 0.0036 0.0243 0.0278
Onchocerca volvulus 0.0147 0.1899 0.1874
Trichomonas vaginalis glutamate synthase, putative 0.0021 0.0031 0.0009
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Brugia malayi Bromodomain containing protein 0.0145 0.1872 0.2139
Echinococcus multilocularis g-protein coupled receptor 0.0147 0.1899 0.2851
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0246 0.0225
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.0447 0.0657
Brugia malayi nuclear receptor RXR 0.0025 0.0082 0.0094
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0021 0.0031 0.0007
Trypanosoma brucei superoxide dismutase, putative 0.0037 0.0258 0.0379
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0082 0.0094
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.1105 0.1645
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0082 0.0094
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0147 0.1899 0.2851
Echinococcus granulosus rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Trypanosoma brucei iron superoxide dismutase 0.0064 0.0671 0.0987
Trypanosoma cruzi ISWI complex protein 0.003 0.0156 0.0229
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0552 0.1057
Schistosoma mansoni hypothetical protein 0.0039 0.0293 0.0588
Schistosoma mansoni glutamate synthase 0.0021 0.0031 0.002
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0225 0.3061 0.6055
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0031 0.0009
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.026 0.0363
Brugia malayi conserved hypotetical protein 0.0025 0.0082 0.0094
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0031 0.0045
Schistosoma mansoni gabp alpha 0.007 0.0754 0.1585
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.012 0.1502 0.3204
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0082 0.0131
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0028 0.0137 0.0719
Mycobacterium leprae POSSIBLE OXIDOREDUCTASE 0.0024 0.0077 0.0092
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0024 0.0077 0.0084
Trichomonas vaginalis superoxide dismutase [fe], putative 0.0064 0.0671 0.0651
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0024 0.0077 0.0099
Echinococcus multilocularis phospholipase A 2 activating protein 0.0035 0.0233 0.0321
Trypanosoma brucei unspecified product 0.0034 0.0225 0.0331
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0024 0.0077 0.012
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0082 0.0094
Mycobacterium tuberculosis Possible oxidoreductase 0.0024 0.0077 0.0099
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.008 0.0901 0.1324
Schistosoma mansoni biogenic amine receptor 0.0147 0.1899 0.4062
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0024 0.0077 0.0152
Brugia malayi neuropeptide F receptor 0.0147 0.1899 0.217
Loa Loa (eye worm) hypothetical protein 0.0028 0.0126 0.0144
Brugia malayi hypothetical protein 0.0025 0.0082 0.0094
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0147 0.1899 0.2851
Echinococcus granulosus tachykinin peptides receptor 99D 0.0147 0.1899 0.2851
Onchocerca volvulus 0.0024 0.0077 0.0046
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.008 0.0901 0.1752
Echinococcus multilocularis neuropeptide receptor A26 0.0147 0.1899 0.2851
Echinococcus granulosus GA binding protein alpha chain 0.007 0.0754 0.1112
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0056 0.0552 0.0532
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0465 0.6609 1
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0624 0.0915
Schistosoma mansoni opsin-like receptor 0.0147 0.1899 0.4062
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0021 0.0031 0.0014
Toxoplasma gondii thioredoxin reductase 0.023 0.3134 0.6201
Plasmodium vivax superoxide dismutase [Fe], putative 0.0037 0.0258 0.0471
Mycobacterium tuberculosis Possible oxidoreductase 0.0024 0.0077 0.0099
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0082 0.0052
Schistosoma mansoni inositol monophosphatase 0.0036 0.0246 0.0485
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0147 0.1899 0.2851
Plasmodium falciparum importin beta, putative 0.0028 0.0131 0.0218
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0021 0.0031 0.0014
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0021 0.0031 0.0106
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0225 0.0331
Schistosoma mansoni hypothetical protein 0.0163 0.2138 0.4579
Brugia malayi Thioredoxin reductase 0.023 0.3134 0.3581
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Entamoeba histolytica hypothetical protein 0.0039 0.0293 0.1687
Echinococcus granulosus ecdysone induced protein 78C 0.0052 0.0492 0.0714
Leishmania major DNA polymerase kappa, putative 0.0021 0.0027 0.004
Mycobacterium ulcerans oxidoreductase 0.0024 0.0077 0.0152
Loa Loa (eye worm) hypothetical protein 0.0028 0.0126 0.0144
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0031 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0052 0.0492 0.0562
Schistosoma mansoni hypothetical protein 0.0025 0.0082 0.0132
Schistosoma mansoni histamine h1 receptor 0.0147 0.1899 0.4062
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0147 0.1899 0.2851
Echinococcus granulosus peptide allatostatin:somatostatin 0.0147 0.1899 0.2851
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Schistosoma mansoni growth hormone secretagogue receptor 0.0147 0.1899 0.4062
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0024 0.0077 0.0152
Onchocerca volvulus Neuropeptide F receptor homolog 0.0147 0.1899 0.1874
Brugia malayi G-protein coupled receptor 0.0147 0.1899 0.217
Trypanosoma cruzi guanine deaminase, putative 0.0129 0.1632 0.24
Echinococcus multilocularis snurportin 1 0.0298 0.414 0.6253
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0322 0.0474
Brugia malayi Importin beta-1 subunit 0.0028 0.0131 0.0149
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0148 0.0169
Schistosoma mansoni amine GPCR 0.0147 0.1899 0.4062
Loa Loa (eye worm) retinol dehydrogenase 12 0.0024 0.0077 0.0088
Trypanosoma brucei WD domain, G-beta repeat/PFU (PLAA family ubiquitin binding), putative 0.0023 0.0064 0.0094
Schistosoma mansoni sulfide quinone reductase 0.0021 0.0031 0.002
Echinococcus multilocularis neuropeptides capa receptor 0.0147 0.1899 0.2851
Brugia malayi Melatonin receptor type 1A 0.0147 0.1899 0.217
Brugia malayi hypothetical protein 0.0147 0.1899 0.217
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0447 0.0657
Onchocerca volvulus 0.0147 0.1899 0.1874
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0293 0.0412
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0147 0.1899 0.4062
Echinococcus granulosus tm gpcr rhodopsin 0.0147 0.1899 0.2851
Trichomonas vaginalis phospholipase A-2-activating protein, putative 0.0035 0.0233 0.0212
Toxoplasma gondii selenide, water dikinase 0.0021 0.0031 0.0019
Echinococcus multilocularis neuropeptide FF receptor 2 0.0147 0.1899 0.2851
Mycobacterium ulcerans NADH dehydrogenase 0.0021 0.0031 0.0061
Echinococcus multilocularis alkaline phosphatase 0.0314 0.4377 0.6612
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0021 0.0031 0.0019
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0126 0.0226
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0094
Brugia malayi nuclear receptor NHR-88 0.0052 0.0492 0.0562
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0532
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.0447 0.0847
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0552 0.0811
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.012 0.1502 0.2248
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0037 0.026 0.0298
Brugia malayi Dopamine receptor protein 1 0.0147 0.1899 0.217
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.008 0.0901 0.1787
Schistosoma mansoni neuropeptide f receptor 76f 0.0147 0.1899 0.4062
Schistosoma mansoni disulfide oxidoreductase 0.0021 0.0031 0.002
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0077 0.0152
Schistosoma mansoni methyl-cpg binding protein mbd 0.0033 0.0206 0.0401
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0147 0.1899 0.217
Loa Loa (eye worm) steroid hormone receptor 0.0052 0.0492 0.0562
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0056 0.0552 0.1147
Brugia malayi Pre-SET motif family protein 0.0087 0.1012 0.1157
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.008 0.0901 0.1335
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0052 0.0031
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.007 0.0749 0.1105
Echinococcus granulosus biogenic amine 5HT receptor 0.0147 0.1899 0.2851
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.1057
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0024 0.0077 0.0113
Trypanosoma cruzi iron superoxide dismutase, putative 0.0064 0.0671 0.0987
Echinococcus multilocularis neuropeptide s receptor 0.0147 0.1899 0.2851
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0094
Schistosoma mansoni hypothetical protein 0.005 0.0457 0.0943
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0531 0.0607
Echinococcus granulosus glutamate synthase 0.0021 0.0031 0.0014
Schistosoma mansoni superoxide dismutase [mn] 0.0064 0.0671 0.1405
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0624 0.0713
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.008 0.0901 0.1752
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0032 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0322 0.0474
Leishmania major hypothetical protein, conserved 0.0021 0.0031 0.0045
Echinococcus granulosus sex peptide receptor 0.0147 0.1899 0.2851
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0082 0.0092
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.0447 0.0657
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0077 0.0099
Echinococcus granulosus serotonin receptor 0.0147 0.1899 0.2851
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0077 0.0099
Trypanosoma brucei ISWI complex protein 0.003 0.0156 0.0229
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.1105 0.1263
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0021 0.0031 0.0061
Leishmania major iron superoxide dismutase 0.0064 0.0671 0.0987
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0052 0.0492 0.0562
Trypanosoma brucei guanine deaminase, putative 0.0129 0.1632 0.24
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0056 0.0552 0.1147
Trypanosoma brucei pteridine reductase 1 0.0024 0.0077 0.0113
Echinococcus multilocularis allatostatin A receptor 0.0147 0.1899 0.2851
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0082 0.0094
Onchocerca volvulus Superoxide dismutase [Mn], mitochondrial homolog 0.0064 0.0671 0.0642
Schistosoma mansoni hypothetical protein 0.0147 0.1899 0.4062
Loa Loa (eye worm) hypothetical protein 0.006 0.0604 0.069
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0031 0.0045
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0126 0.0144
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.1274 0.1255
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0126 0.0144
Giardia lamblia Hypothetical protein 0.0056 0.0552 0.6034
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0052 0.0492 0.0462
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0147 0.1899 0.2851
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0024 0.0077 0.0345
Trypanosoma cruzi ISWI complex protein 0.003 0.0156 0.0229
Loa Loa (eye worm) G-protein coupled receptor 0.0147 0.1899 0.217
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0116 0.1432 0.2142
Entamoeba histolytica hypothetical protein 0.0039 0.0293 0.1687
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0131 0.0192
Trypanosoma cruzi WD domain, G-beta repeat/PFU (PLAA family ubiquitin binding), putative 0.0035 0.0233 0.0342
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0082 0.0094
Loa Loa (eye worm) hypothetical protein 0.0021 0.0032 0.0037
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0056 0.0552 0.0811
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0225 0.3061 0.4501
Echinococcus granulosus manganese superoxide dismutase 0.0064 0.0671 0.0986
Trichomonas vaginalis apoptosis inducing factor, putative 0.0021 0.0031 0.0009
Leishmania major dihydrolipoamide dehydrogenase, putative 0.008 0.0901 0.1324
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0246 0.0361
Onchocerca volvulus 0.0087 0.1012 0.0985
Schistosoma mansoni importin beta-1 0.0028 0.0131 0.0237
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0021 0.0031 0.0045
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0021 0.0031 0.0035
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0056 0.0552 0.0805
Mycobacterium leprae Probable superoxide dismutase SodA 0.0064 0.0671 0.1278
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0147 0.1899 0.4062
Trypanosoma brucei trypanothione reductase 0.023 0.3134 0.4608
Trichomonas vaginalis glutathione reductase, putative 0.008 0.0901 0.0881
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0056 0.0552 0.0805
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0105 0.1274 0.2482
Leishmania major hypothetical protein, conserved 0.0055 0.0532 0.0783
Schistosoma mansoni biogenic amine receptor 0.0147 0.1899 0.4062
Brugia malayi Superoxide dismutase, mitochondrial precursor, putative 0.0064 0.0671 0.0767
Echinococcus granulosus neuropeptide receptor 0.0147 0.1899 0.2851
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0175 0.0257
Mycobacterium ulcerans monoxygenase 0.0021 0.0031 0.0061
Onchocerca volvulus Superoxide dismutase [Mn], mitochondrial homolog 0.0064 0.0671 0.0642
Plasmodium falciparum ataxin-2 like protein, putative 0.0055 0.0532 0.1018
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0094
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0077 0.0088
Loa Loa (eye worm) thioredoxin reductase 0.023 0.3134 0.3581
Loa Loa (eye worm) hypothetical protein 0.0052 0.0492 0.0562
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0478 0.68 1
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0624 0.1304
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.1274 0.1874
Schistosoma mansoni RAR-like nuclear receptor 0.0052 0.0492 0.1017
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0027 0.004
Mycobacterium ulcerans glutamate synthase subunit beta 0.0021 0.0031 0.0061
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0094
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0024 0.0077 0.0113
Plasmodium vivax ferrodoxin reductase, putative 0.0021 0.0031 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0552 0.0532
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Toxoplasma gondii phosphofructokinase PFKII 0.0028 0.0137 0.0231
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0028 0.0137 0.1317
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0027 0.004
Mycobacterium tuberculosis Probable oxidoreductase 0.018 0.2384 0.4701
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0056 0.0552 0.0805
Onchocerca volvulus 0.0025 0.0082 0.0052
Loa Loa (eye worm) hypothetical protein 0.0028 0.0126 0.0144
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0359 0.504 1
Brugia malayi nuclear receptor RXR 0.0028 0.0126 0.0144
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0056 0.0552 0.063
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0082 0.0092
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0082 0.0092
Trypanosoma cruzi guanine deaminase, putative 0.0129 0.1632 0.24
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0588 0.1128
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0359 0.504 1
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0552 0.0811
Schistosoma mansoni hypothetical protein 0.0125 0.1573 0.3357
Brugia malayi TAR-binding protein 0.0061 0.0624 0.0713
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0126 0.0226
Loa Loa (eye worm) TYRA-2 protein 0.0147 0.1899 0.217
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0147 0.1899 0.217
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0024 0.0077 0.0113
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0052 0.0492 0.0562
Loa Loa (eye worm) hypothetical protein 0.0052 0.0492 0.0562
Onchocerca volvulus 0.0147 0.1899 0.1874
Brugia malayi hypothetical protein 0.0055 0.0532 0.0608
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0024 0.0077 0.0113
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0121 0.1514 0.2966
Entamoeba histolytica guanine deaminase, putative 0.0129 0.1632 1
Plasmodium falciparum glutathione reductase 0.023 0.3134 0.6201
Echinococcus multilocularis glutamate synthase 0.0021 0.0031 0.0014
Trichomonas vaginalis glutamate synthase, putative 0.0021 0.0031 0.0009
Echinococcus multilocularis sex peptide receptor 0.0147 0.1899 0.2851
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.1274 0.271
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0052 0.0492 0.1017
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Trypanosoma cruzi iron superoxide dismutase A, mitochondrial 0.0064 0.0671 0.0987
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0044 0.0364 0.0521
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0021 0.0031 0.0058
Onchocerca volvulus 0.0147 0.1899 0.1874
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0021 0.0031 0.0007
Entamoeba histolytica thioredoxin reductase, putative 0.0021 0.0031 0.0058
Leishmania major hypothetical protein, conserved 0.003 0.0156 0.0229
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.1057
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.019 0.0318
Echinococcus granulosus fmrfamide receptor 0.0147 0.1899 0.2851
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0126 0.0144
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0225 0.3061 0.4614
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0021 0.0031 0.0014
Leishmania major ATP-dependent phosphofructokinase 0.0105 0.1274 0.1874
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.008 0.0901 0.1335
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0447 0.0426
Echinococcus granulosus rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0031 0.0045
Brugia malayi Serotonin receptor 0.0147 0.1899 0.217
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0147 0.1899 0.4062
Trichomonas vaginalis superoxide dismutase, putative 0.0064 0.0671 0.0651
Leishmania major pteridine reductase 1 0.0024 0.0077 0.0113
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0094
Schistosoma mansoni lipoxygenase 0.0127 0.1607 0.3429
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.0492 0.0562
Brugia malayi Ets-domain containing protein 0.007 0.0754 0.0862
Trichomonas vaginalis superoxide dismutase [fe], putative 0.0064 0.0671 0.0651
Brugia malayi hypothetical protein 0.0147 0.1899 0.217
Loa Loa (eye worm) hypothetical protein 0.0023 0.0064 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0322 0.0474
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0035
Schistosoma mansoni alkaline phosphatase 0.0314 0.4377 0.9422
Plasmodium falciparum ataxin-2 like protein, putative 0.0055 0.0532 0.1018
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0021 0.0031 0.0045
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0056 0.0552 0.1147
Schistosoma mansoni voltage-gated potassium channel 0.004 0.031 0.0625
Echinococcus granulosus zinc finger protein 0.0038 0.0279 0.0391
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0322 0.0474
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.1105 0.1263
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0021 0.0031 0.0014
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0293 0.0588
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0624 0.1304
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0052 0.0492 0.1017
Trypanosoma cruzi PAB1-binding protein , putative 0.0055 0.0532 0.0783
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0246 0.0429
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0056 0.0552 0.0811
Trypanosoma cruzi WD domain, G-beta repeat/PFU (PLAA family ubiquitin binding), putative 0.0035 0.0233 0.0342
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0052 0.0492 0.0714
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.1274 0.1456
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0056 0.0552 0.0532
Trichomonas vaginalis guanine deaminase, putative 0.0129 0.1632 0.1614
Leishmania major superoxide dismutase, putative 0.0037 0.0258 0.0379
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0359 0.504 1
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Plasmodium vivax thioredoxin reductase, putative 0.023 0.3134 0.6201
Brugia malayi Fli-1 protein 0.0212 0.2867 0.3276
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0105 0.1274 0.2487
Schistosoma mansoni hypothetical protein 0.0021 0.0031 0.002
Schistosoma mansoni zinc finger protein 0.0038 0.0279 0.0557
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0021 0.0031 0.0061
Brugia malayi putative neuropeptide receptor 0.0147 0.1899 0.217
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0147 0.1899 0.2851
Loa Loa (eye worm) hypothetical protein 0.0067 0.0716 0.0818
Plasmodium vivax 6-phosphofructokinase, putative 0.0028 0.0137 0.0231
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0077 0.0152
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0024 0.0077 0.0152
Leishmania major dihydrolipoamide dehydrogenase, putative 0.008 0.0901 0.1324
Mycobacterium ulcerans flavoprotein disulfide reductase 0.008 0.0901 0.1787
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0121 0.1514 0.2961
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0021 0.0031 0.0035
Mycobacterium ulcerans 6-phosphofructokinase 0.0105 0.1274 0.2528
Echinococcus granulosus tar DNA binding protein 0.0061 0.0624 0.0915
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0532
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0225 0.3061 0.4501
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0082 0.0094
Chlamydia trachomatis oxoacy-ACP reductase 0.0024 0.0077 0.0092
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0024 0.0077 0.0152
Onchocerca volvulus Superoxide dismutase [Mn], mitochondrial homolog 0.0044 0.0368 0.0338
Schistosoma mansoni nuclear receptor 0.0025 0.0082 0.0131
Mycobacterium ulcerans superoxide dismutase [Fe] SodA 0.0064 0.0671 0.1331
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0531 0.0607
Brugia malayi putative neuropeptide receptor NPR1 0.0147 0.1899 0.217
Brugia malayi steroid hormone receptor 0.0052 0.0492 0.0562
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0021 0.0031 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1899 0.4062
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0246 0.0447
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0052 0.0492 0.0562
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0021 0.0024
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0052 0.0492 0.0714
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.008 0.0901 0.1324
Brugia malayi hypothetical protein 0.0028 0.0126 0.0144
Plasmodium falciparum glutathione reductase 0.008 0.0901 0.1752
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0094
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0052 0.0077
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0021 0.0031 0.0014
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0031 0.0019
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.1274 0.271
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0032 0.0022
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0082 0.0131
Schistosoma mansoni ets-related 0.0212 0.2867 0.6155
Mycobacterium tuberculosis Probable reductase 0.0121 0.1514 0.2966
Echinococcus multilocularis carboxylesterase 5A 0.0067 0.0716 0.1055
Brugia malayi PHD-finger family protein 0.0048 0.0432 0.0494
Brugia malayi hypothetical protein 0.0025 0.0082 0.0094
Onchocerca volvulus 0.0147 0.1899 0.1874
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0609 0.8752 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0532
Echinococcus multilocularis 6 phosphofructokinase 0.0105 0.1274 0.1902
Brugia malayi G protein-coupled receptor F59B2.13 0.0147 0.1899 0.217
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0624 0.1304
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0094
Loa Loa (eye worm) phosphofructokinase 0.0105 0.1274 0.1456
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0024 0.0077 0.0111
Echinococcus granulosus single minded 2 0.0038 0.0282 0.0396
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0246 0.1393
Loa Loa (eye worm) hypothetical protein 0.0028 0.0126 0.0144
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0147 0.1899 0.217
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Brugia malayi ORL1-like opioid receptor 0.0147 0.1899 0.217
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0137 0.0116
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0232 0.0461
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0056 0.0552 0.0811
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0052 0.0492 0.0562
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0077 0.0152
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.008 0.0901 0.1902
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0532
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0052 0.0492 0.1017
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.0447 0.0645
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0021 0.0031 0.0058
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0447 0.0426
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0024 0.0077 0.0113
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0056 0.0552 0.0532
Trypanosoma cruzi iron superoxide dismutase, putative 0.0044 0.0368 0.0541
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0032 0.0017
Schistosoma mansoni loxhd1 0.0021 0.0032 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0447 0.092
Brugia malayi ecdysteroid receptor 0.0052 0.0492 0.0562
Schistosoma mansoni alkaline phosphatase 0.0314 0.4377 0.9422
Trypanosoma cruzi iron superoxide dismutase A, mitochondrial 0.0064 0.0671 0.0987
Onchocerca volvulus 0.0147 0.1899 0.1874
Schistosoma mansoni amine GPCR 0.0147 0.1899 0.4062
Loa Loa (eye worm) neuropeptide F receptor 0.0147 0.1899 0.217
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0052 0.0492 0.0714
Echinococcus granulosus rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1899 0.2851
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0021 0.0031 0.0061
Schistosoma mansoni hypothetical protein 0.004 0.0309 0.0623
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0532
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0147 0.1899 0.217
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.0447 0.051
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0314 0.4377 0.6612
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0032 0.0017
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.008 0.0901 0.1324
Echinococcus multilocularis GA binding protein alpha chain 0.007 0.0754 0.1112
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0322 0.0639
Echinococcus granulosus histone lysine methyltransferase setb 0.012 0.1502 0.2248
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0021 0.0031 0.0019
Brugia malayi AKH receptor 0.0147 0.1899 0.217
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0056 0.0552 0.1147
Brugia malayi hypothetical protein 0.0021 0.0032 0.0037
Echinococcus granulosus 7TM GPCR rhodopsin 0.0147 0.1899 0.2851
Brugia malayi Serotonin receptor 0.0147 0.1899 0.217
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0052 0.0492 0.0714
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0105 0.1274 1
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Loa Loa (eye worm) melatonin receptor type 1A 0.0147 0.1899 0.217
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0028 0.0137 0.0231
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Schistosoma mansoni thyroid hormone receptor 0.0177 0.2349 0.5034
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0021 0.0031 0.0061
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0082 0.0092
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0147 0.1899 0.4062
Schistosoma mansoni polycystin 1-related 0.0021 0.0032 0.0024
Brugia malayi G-protein coupled receptor 0.0147 0.1899 0.217
Brugia malayi hypothetical protein 0.0146 0.1888 0.2157
Loa Loa (eye worm) G-protein coupled receptor 0.0147 0.1899 0.217
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0322 0.0474
Plasmodium vivax glutathione reductase, putative 0.023 0.3134 0.6201
Echinococcus granulosus neuropeptide Y receptor 0.0147 0.1899 0.2851
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0147 0.1899 0.217
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0552 0.1057
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0137 0.0116
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0314 0.4377 0.6612
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0077 0.0152
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0322 0.0457
Loa Loa (eye worm) hypothetical protein 0.0056 0.0552 0.063
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0131 0.0192
Schistosoma mansoni nuclear receptor 0.0025 0.0082 0.0131
Schistosoma mansoni lipoxygenase 0.0089 0.1038 0.2199
Trichomonas vaginalis phosphofructokinase, putative 0.0028 0.0137 0.0116
Brugia malayi RE15519p 0.0147 0.1899 0.217
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.008 0.0901 0.1736
Trypanosoma cruzi superoxide dismutase, putative 0.0037 0.0258 0.0379
Schistosoma mansoni zinc finger protein 0.0025 0.0082 0.0131
Echinococcus granulosus alpha 1A adrenergic receptor 0.0147 0.1899 0.2851
Brugia malayi hypothetical protein 0.0147 0.1899 0.217
Echinococcus granulosus RUN 0.0021 0.0032 0.0017
Echinococcus multilocularis acetylcholinesterase 0.0067 0.0716 0.1055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1899 0.4062
Schistosoma mansoni opsin-like receptor 0.0147 0.1899 0.4062
Schistosoma mansoni rab6-interacting 0.0021 0.0032 0.0024
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.0532
Brugia malayi hypothetical protein 0.0021 0.0032 0.0037
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.008 0.0901 0.1324
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0465 0.6609 1
Leishmania major oxidoreductase-like protein 0.0024 0.0077 0.0113
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0032 0.0017
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0322 0.0474
Echinococcus granulosus neuropeptide receptor 0.0147 0.1899 0.2851
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0021 0.0031 0.0014
Brugia malayi hypothetical protein 0.0147 0.1899 0.217
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0147 0.1899 0.217
Trypanosoma cruzi iron superoxide dismutase, putative 0.0064 0.0671 0.0987
Echinococcus multilocularis G-protein coupled receptor, putative 0.0147 0.1899 0.2851
Plasmodium vivax superoxide dismutase [Fe], putative 0.0064 0.0671 0.1295
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0087 0.1012 0.1974
Loa Loa (eye worm) hypothetical protein 0.0147 0.1899 0.217
Echinococcus multilocularis FTZ F1 alpha 0.0052 0.0492 0.0714
Loa Loa (eye worm) PDE1B protein 0.0225 0.3061 0.3497
Brugia malayi polk-prov protein 0.0031 0.0175 0.02
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0077 0.0152
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0126 0.0159
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0056 0.0552 0.1057
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0082 0.0092
Loa Loa (eye worm) hypothetical protein 0.0031 0.0175 0.02
Entamoeba histolytica hypothetical protein 0.0023 0.0053 0.02
Schistosoma mansoni glutamate synthase 0.0021 0.0031 0.002
Echinococcus granulosus dna polymerase kappa 0.0041 0.0322 0.0457
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0021 0.0031 0.0058
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.008 0.0901 0.1324
Trichomonas vaginalis phospholipase A-2-activating protein, putative 0.0023 0.0064 0.0043
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.1105 0.1645
Mycobacterium ulcerans ferredoxin reductase 0.0021 0.0031 0.0061
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0552 0.1057
Schistosoma mansoni neuropeptide receptor 0.0147 0.1899 0.4062
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0028 0.0137 0.0213
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0031 0.0045
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0032 0.0017
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.008 0.0901 0.1752
Brugia malayi sulfakinin receptor protein 0.0147 0.1899 0.217
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0225 0.0204
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0116 0.1432 0.2142
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0021 0.0031 0.0035
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0052 0.0492 0.0562

Activities

Activity type Activity value Assay description Source Reference
LC50 (functional) > 500 mg/L Larvicidal activity against Oriental armyworm ChEMBL. 17897833

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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