Detailed information for compound 506104

Basic information

Technical information
  • TDR Targets ID: 506104
  • Name: 2-[1-[(2R,6R)-1-(4-chlorophenyl)sulfonyl-6-et hylpiperidin-2-yl]cyclopropyl]-1-[(3R)-3-hydr oxypyrrolidin-1-yl]ethanone
  • MW: 455.011 | Formula: C22H31ClN2O4S
  • H donors: 1 H acceptors: 4 LogP: 3.12 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC[C@@H]1CCC[C@@H](N1S(=O)(=O)c1ccc(cc1)Cl)C1(CC1)CC(=O)N1CC[C@H](C1)O
  • InChi: 1S/C22H31ClN2O4S/c1-2-17-4-3-5-20(25(17)30(28,29)19-8-6-16(23)7-9-19)22(11-12-22)14-21(27)24-13-10-18(26)15-24/h6-9,17-18,20,26H,2-5,10-15H2,1H3/t17-,18-,20-/m1/s1
  • InChiKey: FVHUZYZMUXKNEP-QWFCFKBJSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-[1-[(2R,6R)-1-(4-chlorophenyl)sulfonyl-6-ethyl-2-piperidyl]cyclopropyl]-1-[(3R)-3-hydroxypyrrolidin-1-yl]ethanone
  • 2-[1-[(2R,6R)-1-(4-chlorophenyl)sulfonyl-6-ethyl-2-piperidinyl]cyclopropyl]-1-[(3R)-3-hydroxy-1-pyrrolidinyl]ethanone
  • 2-[1-[(2R,6R)-1-(4-chlorophenyl)sulfonyl-6-ethyl-piperidin-2-yl]cyclopropyl]-1-[(3R)-3-hydroxypyrrolidin-1-yl]ethanone
  • 2-[1-[(2R,6R)-1-(4-chlorophenyl)sulfonyl-6-ethyl-2-piperidyl]cyclopropyl]-1-[(3R)-3-hydroxypyrrolidino]ethanone

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania major cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma congolense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans closely related to C.maltosa N-alkane-inducible cytochrome P-450, alkane hydroxylating monooxygenase CYP52A3-b aka P450Alk1A (BA Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania infantum cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans cytochrome P450 556 Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) CYP4Cod1 Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans cytochrome P450 56 Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma brucei gambiense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania braziliensis cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma brucei cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania mexicana cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania donovani cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi cytochrome P450 cytochrome P450, family 3, subfamily A, polypeptide 4 502 aa 492 aa 24.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0004 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1041 0.2886
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.0079 0.0077
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0004 0.0012
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0019 0.0017 0.0039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0013
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0041
Brugia malayi hypothetical protein 0.0055 0.0154 0.0444
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0194 0.056
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0026 0.0044 0.0149
Echinococcus granulosus neuropeptides capa receptor 0.0055 0.0154 0.0287
Leishmania major hypothetical protein, conserved 0.0035 0.0079 0.0077
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0039 0.0094 0.0258
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0025 0.0038 0.0067
Loa Loa (eye worm) carboxylesterase 0.0636 0.2387 0.6963
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Echinococcus granulosus RUN 0.0156 0.0543 0.102
Echinococcus multilocularis lipoxygenase domain containing protein 0.0156 0.0543 0.102
Onchocerca volvulus 0.0156 0.0543 0.15
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0043
Schistosoma mansoni jumonji domain containing protein 0.0132 0.0449 0.0843
Echinococcus multilocularis G protein coupled receptor 139 0.0055 0.0154 0.0287
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0042 0.011
Plasmodium falciparum amino acid transporter, putative 0.0026 0.0044 0.0115
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0017 0.0015
Schistosoma mansoni chromobox protein 0.0068 0.0205 0.0383
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.008 0.0217
Plasmodium falciparum LCCL domain-containing protein 0.0156 0.0543 0.1574
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0017 0.0015
Echinococcus granulosus retinol dehydrogenase 11 0.0019 0.0017 0.0028
Brugia malayi Carboxylesterase family protein 0.0636 0.2387 0.6963
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0044 0.0127
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0043
Toxoplasma gondii hypothetical protein 0.0016 0.0003 0.001
Loa Loa (eye worm) dehydrogenase 0.0019 0.0017 0.0043
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0194 0.0687 0.2529
Echinococcus granulosus g protein coupled receptor 0.0055 0.0154 0.0287
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.009 0.0261
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0041 0.0108
Echinococcus multilocularis neuropeptides capa receptor 0.0055 0.0154 0.0287
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0018 0.0014 0.0021
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0191 0.0677 0.1971
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0191 0.0677 0.0675
Leishmania major short chain dehydrogenase/reductase, putative 0.0019 0.0017 0.0015
Echinococcus granulosus lysine specific demethylase 6a 0.0025 0.0038 0.0067
Plasmodium falciparum glutathione reductase 0.0906 0.3427 1
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0039 0.0094 0.0258
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.012 0.0404 0.0758
Echinococcus multilocularis inositol monophosphatase 1 0.0148 0.0514 0.0965
Brugia malayi hypothetical protein 0.0119 0.0401 0.1164
Giardia lamblia GTOR 0.0046 0.0119 0.0426
Loa Loa (eye worm) dehydrogenase 0.0019 0.0017 0.0043
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0084 0.0154
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.0043
Loa Loa (eye worm) acetylcholinesterase 1 0.0636 0.2387 0.6963
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0107 0.0357 0.0984
Leishmania major ATP-dependent phosphofructokinase 0.0106 0.0352 0.035
Loa Loa (eye worm) G-protein coupled receptor 0.0055 0.0154 0.0444
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0004 0.0002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0019 0.0017 0.0028
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0103 0.0339 0.099
Loa Loa (eye worm) G-protein coupled receptor 0.0055 0.0154 0.0444
Schistosoma mansoni hypothetical protein 0.0174 0.0614 0.1153
Loa Loa (eye worm) RecQ helicase 0.0022 0.0028 0.0075
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0719 0.2708 0.2707
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0048 0.0128
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0074 0.0199
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0191 0.0677 0.1977
Brugia malayi Thioredoxin reductase 0.0906 0.3427 1
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0014
Onchocerca volvulus 0.0055 0.0154 0.042
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0172 0.0623
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0017 0.0015
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0005
Brugia malayi beta-lactamase family protein 0.0036 0.008 0.0228
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0191 0.0677 0.1273
Echinococcus granulosus neuropeptide receptor 0.0055 0.0154 0.0287
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0028
Loa Loa (eye worm) neuropeptide F receptor 0.0055 0.0154 0.0444
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0004 0.001
Loa Loa (eye worm) thioredoxin reductase 0.0906 0.3427 1
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0019 0.0017 0.0028
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0931 0.3521 1
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0019 0.0017 0.0015
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.009 0.0251
Loa Loa (eye worm) hypothetical protein 0.0478 0.178 0.5191
Echinococcus granulosus neuropeptide receptor A26 0.0055 0.0154 0.0287
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0055 0.0154 0.0287
Toxoplasma gondii cytochrome p450 superfamily protein 0.0039 0.0094 0.0275
Brugia malayi Cyclic-nucleotide gated cation channel 0.0018 0.0014 0.0033
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0055 0.0154 0.0287
Leishmania major cathepsin L-like protease 0.0063 0.0186 0.0183
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0014
Plasmodium vivax hypothetical protein, conserved 0.0036 0.008 0.0233
Echinococcus granulosus tar DNA binding protein 0.0065 0.0194 0.0362
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0054 0.0143
Brugia malayi putative neuropeptide receptor NPR1 0.0055 0.0154 0.0444
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.0079 0.0077
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0017 0.0133
Brugia malayi Inositol monophosphatase family protein 0.0016 0.0003 0.0003
Schistosoma mansoni lipoxygenase 0.0404 0.1495 0.2815
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0055 0.0154 0.0287
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0046 0.0082
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0044 0.012
Echinococcus granulosus thioredoxin glutathione reductase 0.0906 0.3427 0.646
Loa Loa (eye worm) hypothetical protein 0.0064 0.019 0.0548
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0719 0.2708 0.7899
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0195 0.0193
Echinococcus granulosus tachykinin peptides receptor 99D 0.0055 0.0154 0.0287
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.009 0.0088
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0191 0.0677 0.1877
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0055 0.0154 0.0287
Schistosoma mansoni sulfide quinone reductase 0.0191 0.0677 0.1273
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.009 0.0088
Schistosoma mansoni aryl hydrocarbon receptor 0.0098 0.0319 0.0597
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.0043
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0027 0.0047
Loa Loa (eye worm) hypothetical protein 0.0153 0.0533 0.1548
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0004 0.0012
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0084 0.0298
Onchocerca volvulus 0.0017 0.0007 0.001
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0039 0.0094 0.0336
Brugia malayi hypoxia-induced factor 1 0.0302 0.1105 0.3219
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0041
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Schistosoma mansoni myosin xvIII 0.0055 0.0154 0.0287
Brugia malayi RE15519p 0.0055 0.0154 0.0444
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0019 0.0017 0.0133
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Mycobacterium tuberculosis Possible oxidoreductase 0.0019 0.0017 0.0039
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0194 0.056
Loa Loa (eye worm) hypothetical protein 0.0191 0.0677 0.1971
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0191 0.0677 0.1877
Plasmodium vivax amine transporter, putative 0.0026 0.0044 0.0125
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0719 0.2708 1
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0019 0.0017 0.0051
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0039 0.0094 0.0336
Brugia malayi beta-lactamase family protein 0.0036 0.008 0.0228
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0039 0.0094 0.0258
Loa Loa (eye worm) phosphofructokinase 0.0106 0.0352 0.1021
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0931 0.3521 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0017 0.0039
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0018 0.0014 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0013
Leishmania major short chain dehydrogenase/reductase, putative 0.0019 0.0017 0.0015
Onchocerca volvulus 0.0019 0.0017 0.0038
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0004 0.0002
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0053 0.0155
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0055 0.0154 0.0444
Leishmania major cytochrome p450-like protein 0.0039 0.0094 0.0092
Leishmania major short chain dehydrogenase-like protein 0.0019 0.0017 0.0015
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0205 0.0593
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0019 0.0017 0.0039
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Mycobacterium ulcerans beta-lactamase 0.0036 0.008 0.0285
Leishmania major hypothetical protein, conserved 0.0019 0.0017 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.012 0.0404 0.0758
Schistosoma mansoni amine GPCR 0.0055 0.0154 0.0287
Schistosoma mansoni inositol monophosphatase 0.0148 0.0514 0.0965
Schistosoma mansoni lipoxygenase 0.0684 0.2574 0.485
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0017 0.0133
Echinococcus granulosus neuroligin 0.0107 0.0357 0.0668
Schistosoma mansoni cytochrome P450 0.0039 0.0094 0.0173
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0119 0.022
Loa Loa (eye worm) doublecortin family protein 0.0156 0.0543 0.1578
Toxoplasma gondii cathepsin CPL 0.0017 0.0007 0.0021
Echinococcus granulosus WW domain containing oxidoreductase 0.0019 0.0017 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0074 0.0199
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0042 0.004
Echinococcus granulosus allatostatin A receptor 0.0055 0.0154 0.0287
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0106 0.0352 0.1123
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Trypanosoma cruzi trypanothione reductase, putative 0.0719 0.2708 0.2707
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0019 0.0017 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0013
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0017 0.0039
Schistosoma mansoni sodium/chloride dependent transporter 0.0026 0.0044 0.0078
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0049 0.0131 0.0242
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0719 0.2708 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.012 0.0404 0.0758
Brugia malayi hypothetical protein 0.0055 0.0154 0.0444
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0041
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Echinococcus multilocularis neuropeptide s receptor 0.0055 0.0154 0.0287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0074 0.0199
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0039 0.0094 0.0336
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0019 0.0017 0.0043
Echinococcus granulosus somatostatin receptor 0.0055 0.0154 0.0287
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0053 0.0155
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0301 0.0564
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0014 0.0031
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0055 0.0154 0.0444
Loa Loa (eye worm) hypothetical protein 0.003 0.0059 0.0164
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0115
Brugia malayi Retinol dehydrogenase 12 0.0019 0.0017 0.0043
Brugia malayi Inositol-1 0.0148 0.0514 0.1494
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0038 0.0036
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.008 0.0147
Onchocerca volvulus 0.0107 0.0357 0.0982
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0025 0.0038 0.0111
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0514 0.0512
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0205 0.0565
Brugia malayi cytochrome P450 0.0039 0.0094 0.0268
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0019 0.0017 0.0015
Schistosoma mansoni biogenic amine (5HT) receptor 0.0055 0.0154 0.0287
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0007 0.0005
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0039
Onchocerca volvulus 0.0951 0.3601 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0045 0.0042
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Onchocerca volvulus 0.0055 0.0154 0.042
Leishmania major cathepsin L-like protease 0.0063 0.0186 0.0183
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0161 0.0462
Echinococcus granulosus acetylcholinesterase 0.0636 0.2387 0.4498
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0074 0.0199
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0194 0.0687 0.0685
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0102 0.0276
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0019 0.0017 0.0043
Schistosoma mansoni neuroligin 3 (S09 family) 0.0107 0.0357 0.0668
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0719 0.2708 0.769
Leishmania major hypothetical protein, conserved 0.0019 0.0017 0.0015
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0039 0.0094 0.0258
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0133 0.0454 0.1282
Onchocerca volvulus 0.0019 0.0017 0.0038
Loa Loa (eye worm) inositol-1 0.0148 0.0514 0.1494
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0055 0.0154 0.0287
Brugia malayi follicle stimulating hormone receptor 0.0316 0.1159 0.3378
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0186 0.0183
Echinococcus multilocularis neuropeptide FF receptor 2 0.0055 0.0154 0.0287
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0228
Leishmania major hypothetical protein, conserved 0.0019 0.0017 0.0015
Brugia malayi hypothetical protein 0.0156 0.0543 0.1578
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0054 0.0143
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.005
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0191 0.0677 0.1273
Schistosoma mansoni hypothetical protein 0.0035 0.0078 0.0142
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0017 0.0015
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0194 0.0687 0.0685
Brugia malayi Cytochrome P450 family protein 0.0058 0.0166 0.0477
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0013
Schistosoma mansoni hypothetical protein 0.0207 0.074 0.1391
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.012
Schistosoma mansoni hypothetical protein 0.0055 0.0154 0.0287
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0057 0.0158
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0719 0.2708 0.7899
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.009 0.0245
Echinococcus granulosus BC026374 protein S09 family 0.0107 0.0357 0.0668
Brugia malayi Uncoordinated protein 44 0.0029 0.0057 0.0158
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0119 0.1112
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0041 0.0073
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0107 0.0357 0.0668
Brugia malayi 6-phosphofructokinase 0.0106 0.0352 0.1021
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0026 0.0044 0.0078
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0119 0.022
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0172 0.0501
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0191 0.0677 0.1967
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0004 0.0003
Leishmania major short chain dehydrogenase, putative 0.0019 0.0017 0.0015
Echinococcus multilocularis somatostatin receptor 0.0055 0.0154 0.0287
Echinococcus multilocularis oxidoreductase 0.0019 0.0017 0.0028
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0191 0.0677 0.1877
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0055 0.0154 0.0287
Mycobacterium tuberculosis Probable reductase 0.0402 0.149 0.4227
Brugia malayi hypothetical protein 0.0019 0.0017 0.0043
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0186 0.0183
Trichomonas vaginalis inositol monophosphatase, putative 0.0148 0.0514 0.1422
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0301 0.0564
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0194 0.0687 0.0685
Schistosoma mansoni pap-inositol-14-phosphatase 0.0016 0.0003 0.0002
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1919 0.7322 0.7322
Echinococcus granulosus tm gpcr rhodopsin 0.0894 0.3382 0.6374
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.008 0.0147
Echinococcus granulosus survival motor neuron protein 1 0.0478 0.178 0.3354
Echinococcus granulosus 7TM GPCR rhodopsin 0.0055 0.0154 0.0287
Echinococcus granulosus inositol monophosphatase 0.0016 0.0003 0.0002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0719 0.2708 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Echinococcus multilocularis neuroligin 0.0107 0.0357 0.0668
Trypanosoma brucei inositol polyphosphate 1-phosphatase, putative 0.0016 0.0003 0.0001
Echinococcus granulosus lamin 0.0055 0.0155 0.0289
Loa Loa (eye worm) serotonin transporter b 0.0153 0.0533 0.1548
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0019 0.0017 0.0039
Schistosoma mansoni retinal dehydrogenase 0.0019 0.0017 0.0028
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0038 0.0104
Loa Loa (eye worm) hypothetical protein 0.031 0.1136 0.3309
Treponema pallidum NADH oxidase 0.0719 0.2708 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.016 0.0557 0.162
Brugia malayi jmjC domain containing protein 0.0092 0.0297 0.0861
Echinococcus multilocularis fmrfamide receptor 0.0055 0.0154 0.0287
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0028
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0039 0.0094 0.0336
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0083 0.0081
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0049 0.0131 0.0375
Trypanosoma cruzi trypanothione reductase, putative 0.0906 0.3427 0.3426
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0054 0.0187
Brugia malayi hypothetical protein 0.0055 0.0154 0.0444
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0019 0.0017 0.0038
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0007 0.0009
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0016 0.0003 0.0002
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0191 0.0677 0.1273
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0043
Schistosoma mansoni jun-related protein 0.0207 0.074 0.1391
Toxoplasma gondii selenide, water dikinase 0.0191 0.0677 0.1977
Brugia malayi Pre-SET motif family protein 0.0836 0.3156 0.9208
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.064 0.1771
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0194 0.0687 0.1945
Echinococcus granulosus hypothetical protein 0.0754 0.2844 0.5359
Entamoeba histolytica hypothetical protein 0.0037 0.0086 0.0795
Plasmodium vivax steroid dehydrogenase, putative 0.0019 0.0017 0.0048
Giardia lamblia Short-chain dehydrogenase, putative 0.0019 0.0017 0.0051
Schistosoma mansoni hypothetical protein 0.0055 0.0154 0.0287
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0161 0.0462
Mycobacterium ulcerans hypothetical protein 0.0191 0.0677 0.2492
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0038 0.01
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0352 0.0972
Mycobacterium ulcerans short-chain type oxidoreductase 0.0019 0.0017 0.0051
Onchocerca volvulus Alhambra homolog 0.0028 0.0053 0.0138
Schistosoma mansoni biogenic amine receptor 0.0055 0.0154 0.0287
Echinococcus granulosus biogenic amine 5HT receptor 0.0055 0.0154 0.0287
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0018 0.0014 0.0033
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0019 0.0017 0.0028
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0019 0.0017 0.0015
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0191 0.0677 0.1273
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0055 0.0154 0.0287
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.0079 0.0229
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.095 0.2634
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0041 0.0108
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0719 0.2708 1
Schistosoma mansoni biogenic amine receptor 0.0055 0.0154 0.0287
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Echinococcus granulosus intermediate filament protein 0.0055 0.0155 0.0289
Echinococcus multilocularis neuropeptide receptor 0.0055 0.0154 0.0287
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0084 0.0776
Loa Loa (eye worm) hypothetical protein 0.0475 0.1768 0.5155
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0019 0.0017 0.0015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0186 0.0183
Loa Loa (eye worm) hypothetical protein 0.0055 0.0155 0.0447
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Loa Loa (eye worm) hypothetical protein 0.0051 0.014 0.0401
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0026 0.0044 0.0078
Schistosoma mansoni hypothetical protein 0.0039 0.0094 0.0173
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0172 0.032
Schistosoma mansoni myo inositol monophosphatase 0.0016 0.0003 0.0002
Mycobacterium ulcerans hypothetical protein 0.0036 0.008 0.0285
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0018 0.004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0043
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0007 0.0009
Brugia malayi isocitrate dehydrogenase 0.0016 0.0004 0.0005
Toxoplasma gondii NADPH-glutathione reductase 0.0719 0.2708 0.7902
Onchocerca volvulus 0.0107 0.0357 0.0982
Echinococcus multilocularis g protein coupled receptor 0.0055 0.0154 0.0287
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0004 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0039 0.0094 0.0258
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0352 0.066
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0019 0.0017 0.0038
Giardia lamblia NADH oxidase lateral transfer candidate 0.0719 0.2708 1
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0086 0.0158
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.008 0.0285
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Onchocerca volvulus 0.0151 0.0523 0.1444
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0055 0.0154 0.0444
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0041 0.0073
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0013
Brugia malayi RNA binding protein 0.0065 0.0194 0.056
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0055 0.0154 0.0287
Schistosoma mansoni lamin 0.0055 0.0155 0.0289
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0719 0.2708 0.2707
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0103 0.0339 0.0984
Mycobacterium tuberculosis Probable dehydrogenase 0.0402 0.149 0.4227
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0352 0.066
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0186 0.0183
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0191 0.0677 0.1273
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0026 0.0044 0.0078
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0154 0.0287
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0039
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0039 0.0094 0.0258
Loa Loa (eye worm) hypothetical protein 0.0044 0.0111 0.0318
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0179 0.0631 0.0629
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0089 0.0164
Loa Loa (eye worm) hypothetical protein 0.0248 0.0896 0.261
Onchocerca volvulus 0.0055 0.0154 0.042
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0084 0.0154
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.001
Brugia malayi dehydrogenases, short chain protein 9 0.0019 0.0017 0.0043
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.095 0.2634
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0044 0.0078
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0013
Brugia malayi jmjC domain containing protein 0.0025 0.0038 0.0104
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0039 0.0094 0.0258
Schistosoma mansoni rab6-interacting 0.0156 0.0543 0.102
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0007 0.001
Onchocerca volvulus 0.0019 0.0017 0.0038
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.009 0.0256
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0045 0.0042
Onchocerca volvulus 0.0019 0.0017 0.0038
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0373 0.1379 0.4018
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Echinococcus multilocularis lamin dm0 0.0055 0.0155 0.0289
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0038 0.01
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0008 0.001
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0039 0.0094 0.0258
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0044 0.0078
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0026 0.0024
Brugia malayi Heterochromatin protein 1 0.0068 0.0205 0.0593
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.0339 0.0337
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Brugia malayi GnHR receptor homolog 0.0055 0.0154 0.0444
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Onchocerca volvulus 0.0017 0.0007 0.001
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0054 0.0145
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0016 0.0003 0.0002
Schistosoma mansoni ankyrin 23/unc44 0.0029 0.0057 0.0102
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0044 0.0078
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0039 0.0094 0.0258
Loa Loa (eye worm) jmjC domain-containing protein 0.0092 0.0297 0.0861
Brugia malayi Tachykinin-like peptides receptor 99D 0.0055 0.0154 0.0444
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.009 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0047 0.0125
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0119 0.022
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0191 0.0677 0.0675
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0019 0.0017 0.0028
Loa Loa (eye worm) hypothetical protein 0.0028 0.0053 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0038 0.0099
Loa Loa (eye worm) carboxylesterase 0.0107 0.0357 0.1034
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0053 0.0096
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0039 0.0094 0.0336
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0191 0.0677 0.1273
Leishmania major hypothetical protein, conserved 0.0026 0.0042 0.004
Echinococcus granulosus acetylcholinesterase 0.0636 0.2387 0.4498
Loa Loa (eye worm) hypothetical protein 0.012 0.0404 0.1174
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0191 0.0677 0.1273
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.008 0.0078
Brugia malayi glutamate synthase 0.0191 0.0677 0.1971
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0191 0.0677 0.6499
Echinococcus multilocularis Ankyrin 0.003 0.0057 0.0104
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0301 0.0564
Onchocerca volvulus 0.0072 0.0221 0.0606
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.2199 0.8396 0.8396
Brugia malayi putative neuropeptide receptor 0.0055 0.0154 0.0444
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0039 0.0094 0.0336
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0013
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0191 0.0677 0.0675
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0019 0.0017 0.0133
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0084 0.0154
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0055 0.0154 0.0287
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0078 0.022
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0191 0.0677 0.1273
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0172 0.032
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0191 0.0677 0.1273
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0055 0.0154 0.0287
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0017 0.0028
Echinococcus granulosus peptide allatostatin:somatostatin 0.0055 0.0154 0.0287
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0041
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0195 0.0563
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0017 0.0028
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0119 0.034
Brugia malayi MAP kinase sur-1 0.0103 0.0339 0.0984
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.0079 0.0231
Onchocerca volvulus 0.0131 0.0447 0.1234
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0107 0.0357 0.0668
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0133 0.0454 0.1282
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0017 0.0051
Onchocerca volvulus 0.0019 0.0017 0.0038
Brugia malayi Melatonin receptor type 1A 0.0055 0.0154 0.0444
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0301 0.0564
Brugia malayi oxidoreductase 0.0019 0.0017 0.0043
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0017 0.0028
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0042 0.011
Trypanosoma cruzi NADH dehydrogenase, putative 0.0191 0.0677 0.0675
Mycobacterium tuberculosis Probable dehydrogenase 0.0019 0.0017 0.0039
Mycobacterium tuberculosis Probable oxidoreductase 0.0931 0.3521 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0719 0.2708 0.7902
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0719 0.2708 0.2707
Schistosoma mansoni neuropeptide F-like receptor 0.0055 0.0154 0.0287
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0194 0.0362
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0191 0.0677 0.1877
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0006
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0017 0.0015
Leishmania major hypothetical protein, conserved 0.0019 0.0017 0.0015
Onchocerca volvulus Sepiapterin reductase homolog 0.0019 0.0017 0.0038
Brugia malayi G-protein coupled receptor 0.0055 0.0154 0.0444
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0055 0.0154 0.0287
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0191 0.0677 0.1273
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0719 0.2708 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.008 0.0078
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0019 0.0017 0.0039
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0007 0.0014
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0019 0.0017 0.0028
Onchocerca volvulus 0.0017 0.0007 0.001
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0027 0.0047
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0528 0.1974 0.5758
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0055 0.0154 0.0444
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0018 0.0014 0.0021
Entamoeba histolytica hypothetical protein 0.0019 0.0017 0.0133
Schistosoma mansoni carbonyl reductase 0.0019 0.0017 0.0028
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0339 0.0937
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0195 0.0364
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0017 0.0039
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0191 0.0677 0.1916
Schistosoma mansoni amine GPCR 0.0055 0.0154 0.0287
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0017 0.0051
Echinococcus granulosus biogenic amine 5HT receptor 0.0178 0.0629 0.1182
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.009 0.0256
Schistosoma mansoni growth hormone secretagogue receptor 0.0055 0.0154 0.0287
Schistosoma mansoni histamine h1 receptor 0.0055 0.0154 0.0287
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0604 0.1672
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0172 0.0623
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0019 0.0017 0.0039
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0352 0.3362
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0041 0.0039
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0035 0.0079 0.0145
Brugia malayi hypothetical protein 0.0107 0.0357 0.1034
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.014 0.0401
Leishmania major 3-keto-dihydrosphingosine reductase 0.0019 0.0017 0.0015
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0014 0.0021
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.012
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.008 0.0217
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0019 0.0017 0.0051
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0191 0.0677 0.0675
Echinococcus granulosus lipoxygenase domain containing protein 0.0156 0.0543 0.102
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0055 0.0154 0.0287
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0352 0.1021
Echinococcus multilocularis jun protein 0.0255 0.0923 0.1737
Brugia malayi Serotonin receptor 0.0055 0.0154 0.0444
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Onchocerca volvulus 0.0055 0.0154 0.042
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0179 0.0631 0.1783
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0604 0.1672
Onchocerca volvulus 0.0055 0.0154 0.042
Brugia malayi hypothetical protein 0.0055 0.0154 0.0444
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0053 0.0096
Echinococcus multilocularis chromobox protein 1 0.0068 0.0205 0.0383
Schistosoma mansoni ap endonuclease 0.0038 0.009 0.0165
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.012 0.0404 0.0758
Echinococcus multilocularis retinol dehydrogenase 11 0.0019 0.0017 0.0028
Echinococcus granulosus chromobox protein 1 0.0068 0.0205 0.0383
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0154 0.0287
Echinococcus granulosus lysine specific demethylase 5A 0.0092 0.0297 0.0556
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0107 0.0357 0.0668
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0084 0.0082
Schistosoma mansoni phd/f-box containing protein 0.0025 0.0038 0.0067
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0514 0.0512
Giardia lamblia Glutamate synthase 0.0191 0.0677 0.2492
Mycobacterium ulcerans 6-phosphofructokinase 0.0106 0.0352 0.1289
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0054 0.0488
Schistosoma mansoni jumonji/arid domain-containing protein 0.0092 0.0297 0.0556
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0028
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0006 0.0006
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0017 0.0015
Leishmania major hypothetical protein, conserved 0.0191 0.0677 0.0675
Echinococcus granulosus geminin 0.0174 0.0614 0.1153
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0119 0.0116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2199 0.8396 0.8396
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0017 0.0133
Echinococcus multilocularis neuropeptide Y receptor 0.0055 0.0154 0.0287
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.009 0.0271
Echinococcus multilocularis inositol monophosphatase 0.0016 0.0003 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0019 0.0017 0.0028
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0046 0.0082
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.005
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0039 0.0094 0.0336
Leishmania major hypothetical protein, conserved 0.0019 0.0017 0.0015
Echinococcus granulosus neuropeptide receptor 0.0055 0.0154 0.0287
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.0079 0.0231
Toxoplasma gondii hypothetical protein 0.0026 0.0044 0.0127
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.0817 0.2314
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative 0.0016 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0041 0.0113
Loa Loa (eye worm) carboxylesterase 0.0107 0.0357 0.1034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0048 0.0128
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0043
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0006 0.0006
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0055 0.0154 0.0287
Brugia malayi jmjC domain containing protein 0.0025 0.0038 0.0104
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0194 0.0362
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0025 0.0038 0.0036
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0014 0.0021
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0039
Entamoeba histolytica hypothetical protein 0.0037 0.0086 0.0795
Echinococcus granulosus death domain containing protein 0.0029 0.0057 0.0102
Onchocerca volvulus 0.0017 0.0007 0.001
Echinococcus granulosus sodium and chloride dependent glycine 0.0026 0.0044 0.0078
Plasmodium falciparum phd finger protein, putative 0.0028 0.0053 0.0143
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0402 0.149 0.4227
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0055 0.0154 0.0287
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0018 0.0014 0.0021
Schistosoma mansoni jumonji/arid domain-containing protein 0.0092 0.0297 0.0556
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0041 0.0073
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0402 0.149 0.4227
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.064 0.1771
Toxoplasma gondii hypothetical protein 0.0026 0.0044 0.0127
Schistosoma mansoni microtubule-associated protein tau 0.1394 0.5304 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.008 0.0147
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0352 0.035
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0042 0.012
Plasmodium vivax multidomain scavenger receptor, putative 0.0156 0.0543 0.1583
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.0043
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0151 0.0523 0.0982
Loa Loa (eye worm) glutathione reductase 0.0906 0.3427 1
Schistosoma mansoni hypothetical protein 0.0156 0.0543 0.102
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0074 0.0199
Echinococcus multilocularis retinol dehydrogenase 13 0.0019 0.0017 0.0028
Entamoeba histolytica short chain dehydrogenase family protein 0.0019 0.0017 0.0133
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0004 0.0002
Echinococcus multilocularis microtubule associated protein 2 0.1394 0.5304 1
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0039 0.0094 0.0336
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0013
Leishmania major myo-inositol-1 phosphatase, putative 0.0016 0.0003 0.0001
Echinococcus granulosus single minded 2 0.0076 0.0235 0.0438
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0014
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0006 0.001
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0191 0.0677 0.1967
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0039 0.0094 0.0336
Brugia malayi AKH receptor 0.0055 0.0154 0.0444
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0054 0.0157
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1919 0.7322 0.7322
Schistosoma mansoni glutamate synthase 0.0191 0.0677 0.1273
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0019 0.0017 0.0028
Echinococcus granulosus cytochrome P450 2K1 0.0039 0.0094 0.0173
Mycobacterium leprae Possible regulatory protein 0.0025 0.0041 0.0107
Onchocerca volvulus 0.0026 0.0044 0.0112
Onchocerca volvulus 0.0025 0.0041 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0084 0.0227
Plasmodium falciparum steroid dehydrogenase, putative 0.0019 0.0017 0.0038
Trypanosoma brucei oxidoreductase-like protein 0.0019 0.0017 0.0015
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.0144 0.0267
Trypanosoma brucei cytochrome P450, putative 0.0056 0.0161 0.0158
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0195 0.1851
Schistosoma mansoni hypothetical protein 0.0052 0.0145 0.0269
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0238
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0019 0.0017 0.0038
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0055 0.0154 0.0287
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0019 0.0017 0.0039
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0039 0.0094 0.0258
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Brugia malayi G protein-coupled receptor F59B2.13 0.0055 0.0154 0.0444
Brugia malayi neuropeptide F receptor 0.0055 0.0154 0.0444
Schistosoma mansoni jumonji domain containing protein 0.0025 0.0038 0.0067
Mycobacterium ulcerans glutamate synthase subunit beta 0.0191 0.0677 0.2492
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Echinococcus multilocularis RUN 0.0156 0.0543 0.102
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.009 0.0244
Giardia lamblia PHD finger protein 15 0.0028 0.0053 0.0184
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0038 0.0099
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.008 0.0217
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0191 0.0677 0.2492
Brugia malayi chromobox protein homolog 3 0.0038 0.009 0.0257
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0103 0.0339 0.0337
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0026 0.0044 0.012
Trichomonas vaginalis glutamate synthase, putative 0.0191 0.0677 0.1877
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.009 0.0836
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0116
Treponema pallidum fructose-bisphosphate aldolase 0.0285 0.1041 0.3717
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0055 0.0154 0.0287
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0514 0.0512
Trichomonas vaginalis set domain proteins, putative 0.0951 0.36 1
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0019 0.0017 0.0015
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0004 0.0002
Echinococcus granulosus G protein coupled receptor 139 0.0055 0.0154 0.0287
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0194 0.0362
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.0043
Mycobacterium ulcerans dehydrogenase 0.0191 0.0677 0.2492
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0514 0.0512
Brugia malayi Dopamine receptor protein 2 0.0055 0.0154 0.0444
Echinococcus multilocularis g-protein coupled receptor 0.0055 0.0154 0.0287
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Brugia malayi Pre-SET motif family protein 0.012 0.0404 0.1174
Schistosoma mansoni hypothetical protein 0.0097 0.0318 0.0596
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0102 0.0276
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0084 0.0154
Loa Loa (eye worm) neuropeptide F receptor 0.0055 0.0154 0.0444
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0038 0.0104
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0025
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.0079 0.0219
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0028 0.0075
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0906 0.3427 0.9734
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.0154 0.0287
Onchocerca volvulus 0.0107 0.0357 0.0982
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0127
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.0154 0.0287
Echinococcus granulosus cathepsin l1 0.0017 0.0007 0.0009
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0056 0.0161 0.0581
Onchocerca volvulus Glucosylceramidase homolog 0.0172 0.0604 0.1669
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0019 0.0017 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0017 0.0015
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0191 0.0677 0.1916
Schistosoma mansoni hypothetical protein 0.0055 0.0154 0.0287
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1041 0.2886
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0019 0.0017 0.0039
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.005
Onchocerca volvulus 0.0019 0.0017 0.0038
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0172 0.032
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0086 0.0158
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Brugia malayi PHD-finger family protein 0.0028 0.0053 0.0148
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0039 0.0094 0.0258
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0148 0.0514 0.15
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0004 0.0002
Echinococcus granulosus jumonji domain containing protein 0.004 0.0096 0.0176
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0155 0.0447
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0055 0.0154 0.0444
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0027 0.0072
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0107 0.0357 0.1034
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0148 0.0514 0.1888
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0119 0.0116
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0055 0.0154 0.0287
Echinococcus multilocularis Polycystic kidney disease protein 0.0156 0.0543 0.102
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0115 0.0387 0.0726
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0041
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0019 0.0017 0.0015
Leishmania major short chain dehydrogenase, putative 0.0019 0.0017 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.095 0.2634
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Schistosoma mansoni neuropeptide receptor 0.0055 0.0154 0.0287
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Echinococcus multilocularis cysteine protease 0.0017 0.0007 0.0009
Echinococcus granulosus bloom syndrome protein 0.0022 0.0028 0.0048
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0044 0.0078
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0191 0.0677 0.1916
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0028
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0055 0.0154 0.0444
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0172 0.032
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0039 0.0094 0.0258
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0186 0.0183
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0191 0.0677 0.2492
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0041 0.0039
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0352 0.0972
Echinococcus granulosus retinol dehydrogenase 11 0.0019 0.0017 0.0028
Brugia malayi G protein-coupled receptor 0.0055 0.0154 0.0444
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0013
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0205 0.0565
Schistosoma mansoni chromobox protein 0.0068 0.0205 0.0383
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0148 0.0514 0.4923
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0301 0.0873
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0017 0.0015
Echinococcus multilocularis sodium channel protein 0.012 0.0405 0.0759
Loa Loa (eye worm) hypothetical protein 0.0025 0.0038 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0061 0.0163
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0007 0.0009
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0007 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0017 0.0015
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0083 0.0081
Treponema pallidum sodium- and chloride- dependent transporter 0.0153 0.0533 0.1803
Loa Loa (eye worm) hypothetical protein 0.0107 0.0357 0.1034
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0019 0.0017 0.0015
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0019 0.0017 0.0041
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Mycobacterium leprae Probable lipase LipE 0.0036 0.008 0.0219
Echinococcus multilocularis musashi 0.0055 0.0155 0.0289
Toxoplasma gondii oxidoreductase, putative 0.0019 0.0017 0.005
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0103 0.0339 0.0337
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0027 0.0047
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0179 0.0631 0.2319
Trypanosoma cruzi NADH dehydrogenase, putative 0.0191 0.0677 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0083 0.0224
Trichomonas vaginalis inositol monophosphatase, putative 0.0016 0.0003 0.0003
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0007 0.0009
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0055 0.0154 0.0287
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0191 0.0677 0.2492
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0402 0.149 0.4227
Loa Loa (eye worm) TYRA-2 protein 0.0055 0.0154 0.0444
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.012 0.0404 0.0758
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0019 0.0017 0.0039
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0191 0.0677 0.2492
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0019 0.0017 0.0028
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0028 0.0071
Mycobacterium ulcerans carboxylesterase, LipT 0.0107 0.0357 0.1305
Brugia malayi PAS domain containing protein 0.0098 0.0319 0.0924
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2616 1 1
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0191 0.0677 0.0675
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.003 0.0057 0.0104
Onchocerca volvulus 0.0191 0.0677 0.1874
Echinococcus granulosus lamin dm0 0.0055 0.0155 0.0289
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0017 0.0015
Loa Loa (eye worm) norepinephrine transporter 0.0153 0.0533 0.1548
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.0144 0.0267
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0191 0.0677 0.1977
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0191 0.0677 0.1916
Loa Loa (eye worm) hypothetical protein 0.0153 0.0533 0.1548
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0039 0.0094 0.0336
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0041
Onchocerca volvulus 0.0017 0.0007 0.001
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0179 0.0631 0.1185
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0084 0.0154
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2616 1 1
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0373 0.1379 0.1377
Onchocerca volvulus 0.0055 0.0154 0.042
Brugia malayi dehydrogenases, short chain protein 2 0.0019 0.0017 0.0043
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0604 0.1672
Schistosoma mansoni biogenic amine receptor 0.0055 0.0154 0.0287
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0194 0.0362
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0186 0.0183
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Onchocerca volvulus 0.0019 0.0017 0.0038
Entamoeba histolytica hypothetical protein, conserved 0.0019 0.0017 0.0133
Onchocerca volvulus Netrin receptor homolog 0.0029 0.0057 0.0148
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0017 0.0015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1041 0.2886
Loa Loa (eye worm) RNA binding protein 0.0065 0.0194 0.056
Mycobacterium leprae Probable oxidoreductase 0.0019 0.0017 0.0039
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0014 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0048 0.0126
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.008 0.0285
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0228
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0044 0.0078
Echinococcus granulosus sodium and chloride dependent glycine 0.0026 0.0044 0.0078
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0007 0.0009
Echinococcus multilocularis sodium and chloride dependent glycine 0.0026 0.0044 0.0078
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0055 0.0154 0.0444
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0055 0.0154 0.0444
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0039 0.0094 0.0336
Echinococcus multilocularis hyperpolarization activated cyclic 0.0018 0.0014 0.0021
Brugia malayi Dehydrogenases, short chain protein 30 0.0019 0.0017 0.0043
Echinococcus granulosus 7tm_1 domain containing protein 0.0055 0.0154 0.0287
Loa Loa (eye worm) beta-lactamase 0.0036 0.008 0.0228
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0043
Brugia malayi hypothetical protein 0.0016 0.0007 0.0014
Echinococcus multilocularis sodium and chloride dependent glycine 0.0026 0.0044 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0084 0.0227
Echinococcus multilocularis peregrin 0.0028 0.0053 0.0096
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0019 0.0017 0.0039
Echinococcus multilocularis neuropeptide receptor A26 0.0055 0.0154 0.0287
Mycobacterium ulcerans ferredoxin reductase 0.0191 0.0677 0.2492
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.095 0.2634
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0016 0.0003 0.0003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0102 0.0273
Toxoplasma gondii carbonyl reductase 1, putative 0.0019 0.0017 0.005
Schistosoma mansoni 60S ribosomal protein L21 0.0017 0.0008 0.001
Schistosoma mansoni protein phosphatase 2C 0.0025 0.0038 0.0067
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1041 0.2886
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0089 0.0164
Echinococcus granulosus g protein coupled receptor 0.0055 0.0154 0.0287
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0191 0.0677 0.6499
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.0043
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0054 0.0143
Onchocerca volvulus 0.0036 0.008 0.0214
Echinococcus multilocularis acetylcholinesterase 0.0636 0.2387 0.4498
Giardia lamblia Reductase, putative 0.0019 0.0017 0.0051
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0014 0.0021
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.005
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0402 0.149 0.4227
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0195 0.0193
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0636 0.2387 0.4498
Loa Loa (eye worm) hypothetical protein 0.0373 0.1379 0.4018
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0074 0.0199
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0039 0.0094 0.0258
Trypanosoma cruzi short chain dehydrogenase, putative 0.0019 0.0017 0.0015
Loa Loa (eye worm) CYP4Cod1 0.0056 0.0161 0.0462
Echinococcus multilocularis jumonji domain containing 1A 0.0025 0.0038 0.0067
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0017 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.0043
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0039
Onchocerca volvulus 0.0055 0.0154 0.042
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0038 0.0036
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0316 0.1159 0.3378
Echinococcus granulosus peregrin 0.0028 0.0053 0.0096
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0318 0.0922
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Schistosoma mansoni adenoreceptor 0.0055 0.0154 0.0287
Brugia malayi hypothetical protein 0.0055 0.0154 0.0444
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0017 0.0051
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0191 0.0677 0.2492
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0054 0.0145
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0191 0.0677 0.6499
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0019 0.0017 0.0051
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0019 0.0017 0.0039
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Echinococcus multilocularis retinol dehydrogenase 11 0.0019 0.0017 0.0028
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0055 0.0154 0.0287
Echinococcus multilocularis mitogen activated protein kinase 3 0.0103 0.0339 0.0636
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0041 0.0108
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0017 0.0039
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0191 0.0677 0.1916
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.0079 0.0077
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0339 0.0937
Echinococcus multilocularis neuropeptide Y receptor 0.0055 0.0154 0.0287
Brugia malayi ORL1-like opioid receptor 0.0055 0.0154 0.0444
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0057 0.016
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0153 0.0533 0.1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0148 0.0514 0.1422
Echinococcus multilocularis hyperpolarization activated cyclic 0.0018 0.0014 0.0021
Echinococcus granulosus serotonin transporter 0.0153 0.0533 0.1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Brugia malayi jmjC domain containing protein 0.0025 0.0038 0.0104
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0165 0.0162
Echinococcus multilocularis lysine specific demethylase 5A 0.0092 0.0297 0.0556
Echinococcus multilocularis transfer RNA-Lys 0.0072 0.0221 0.0413
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0191 0.0677 0.1877
Plasmodium vivax glutathione reductase, putative 0.0906 0.3427 1
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0017 0.0051
Brugia malayi hypothetical protein 0.0037 0.0086 0.0244
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.0016 0.0003 0.0001
Schistosoma mansoni glutamate synthase 0.0191 0.0677 0.1273
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0055 0.0154 0.0287
Loa Loa (eye worm) hypoxia-induced factor 1 0.0302 0.1105 0.3219
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.009 0.032
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0339 0.0937
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0119 0.0116
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Entamoeba histolytica short chain dehydrogenase family protein 0.0019 0.0017 0.0133
Loa Loa (eye worm) hypothetical protein 0.0178 0.0629 0.1829
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0044 0.0078
Brugia malayi hypothetical protein 0.0055 0.0154 0.0444
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0093 0.0252
Schistosoma mansoni hypothetical protein 0.0055 0.0154 0.0287
Toxoplasma gondii exonuclease III APE 0.0038 0.009 0.0263
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1041 0.2886
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0228
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0191 0.0677 0.2492
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0191 0.0677 0.0675
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0019 0.0017 0.0038
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0191 0.0677 0.0675
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0017 0.0028
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Schistosoma mansoni gliotactin 0.0107 0.0357 0.0668
Schistosoma mansoni hypothetical protein 0.0028 0.0053 0.0096
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0041
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.008 0.0219
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0179 0.0631 0.1835
Echinococcus multilocularis thioredoxin glutathione reductase 0.0906 0.3427 0.646
Leishmania major hypothetical protein, conserved 0.0191 0.0677 0.0675
Leishmania major protein kinase, putative 0.0026 0.0045 0.0042
Trichomonas vaginalis glutathione reductase, putative 0.0719 0.2708 0.7522
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0026 0.0044 0.012
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0028
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0004 0.0003
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0191 0.0677 0.1977
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0719 0.2708 0.2707
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0019 0.0017 0.0041
Trypanosoma brucei hypothetical protein, conserved 0.0191 0.0677 0.0675
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0191 0.0677 0.1916
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0007 0.0009
Schistosoma mansoni sodium-dependent amino acid transporter 0.0026 0.0044 0.0078
Echinococcus multilocularis glutamate synthase 0.0191 0.0677 0.1273
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0191 0.0677 0.2492
Onchocerca volvulus 0.0019 0.0017 0.0038
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0055 0.0154 0.0287
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.008 0.0147
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0041
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0041 0.0113
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0719 0.2708 0.7902
Mycobacterium tuberculosis Conserved protein 0.0036 0.008 0.0219
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.008 0.0219
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0018 0.0014 0.0021
Echinococcus granulosus fmrfamide receptor 0.0055 0.0154 0.0287
Onchocerca volvulus 0.0019 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.012
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0262 0.095 0.2767
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.009 0.0088
Echinococcus multilocularis G-protein coupled receptor, putative 0.0055 0.0154 0.0287
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0096 0.0176
Echinococcus granulosus hyperpolarization activated cyclic 0.0018 0.0014 0.0021
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0019 0.0017 0.0039
Schistosoma mansoni opsin-like receptor 0.0055 0.0154 0.0287
Echinococcus multilocularis chromobox protein 1 0.0068 0.0205 0.0383
Mycobacterium ulcerans monoxygenase 0.0191 0.0677 0.2492
Loa Loa (eye worm) hypothetical protein 0.0038 0.009 0.0257
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0045 0.0042
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0054 0.0187
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0027 0.0047
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0025 0.0038 0.0067
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0043
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.0339 0.0337
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0026 0.0044 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0119 0.0324
Echinococcus multilocularis mitogen activated protein kinase 0.0103 0.0339 0.0636
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0007 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0083 0.0224
Echinococcus multilocularis steroid dehydrogenase 0.0019 0.0017 0.0028
Echinococcus multilocularis lamin 0.0055 0.0155 0.0289
Brugia malayi larval opioid receptor 0.0055 0.0154 0.0444
Echinococcus granulosus glutamate synthase 0.0191 0.0677 0.1273
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0019 0.0017 0.0043
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0026 0.0044 0.012
Brugia malayi hypothetical protein 0.0026 0.0042 0.0115
Echinococcus multilocularis serotonin receptor 0.0178 0.0629 0.1182
Brugia malayi beta-lactamase 0.0036 0.008 0.0228
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0039
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0054 0.0187
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0039 0.0094 0.0092
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0119 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0057 0.0153
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.009 0.0136
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0179 0.0631 0.1185
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0033
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0604 0.1672
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0054 0.0156
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0004 0.0003
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0042 0.004
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0191 0.0677 0.1916
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.0154 0.0287
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0039
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0134 0.0132
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0006 0.0006
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0084 0.0154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Trichomonas vaginalis spcc417.12 protein, putative 0.0107 0.0357 0.0984
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0006 0.001
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0352 0.0972
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Trichomonas vaginalis inositol monophosphatase, putative 0.0016 0.0003 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0301 0.0564
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0055 0.0154 0.0287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0083 0.0224
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0005
Treponema pallidum thioredoxin reductase (trxB) 0.0191 0.0677 0.2349
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0684 0.2574 0.485
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0186 0.0183
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0179 0.0631 0.2319
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.008 0.0217
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0072
Brugia malayi Cytochrome P450 family protein 0.0056 0.0161 0.0462
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0014 0.0031
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.0154 0.0287
Trypanosoma brucei NADH dehydrogenase 0.0191 0.0677 0.0675
Loa Loa (eye worm) hypothetical protein 0.0156 0.0543 0.1578
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0006
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0007 0.0014
Leishmania major cytochrome p450-like protein 0.0039 0.0094 0.0092
Loa Loa (eye worm) hypothetical protein 0.0153 0.0533 0.1548
Brugia malayi Carboxylesterase family protein 0.0107 0.0357 0.1034
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Echinococcus granulosus histone lysine methyltransferase setb 0.012 0.0404 0.0758
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2616 1 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.008 0.0219
Echinococcus granulosus chromobox protein 1 0.0068 0.0205 0.0383
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0055 0.0154 0.0287
Echinococcus granulosus sex peptide receptor 0.0055 0.0154 0.0287
Schistosoma mansoni rab6-interacting 0.0156 0.0543 0.102
Onchocerca volvulus 0.0055 0.0154 0.042
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0018 0.0014 0.0021
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0684 0.2574 0.485
Brugia malayi bZIP transcription factor family protein 0.0255 0.0923 0.2689
Echinococcus granulosus Ankyrin 0.003 0.0057 0.0104
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0352 0.035
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.008 0.0228
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0047 0.0125
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0026 0.0044 0.0078
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Schistosoma mansoni opsin-like receptor 0.0055 0.0154 0.0287
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.014 0.0401
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0019 0.0017 0.0015
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.008 0.0216
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.0479 0.1353
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0172 0.0169
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0019 0.0017 0.0015
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0041 0.0073
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0039 0.0094 0.0258
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.0043
Brugia malayi SET domain containing protein 0.0016 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0016 0.0003 0.0002
Entamoeba histolytica hypothetical protein 0.0037 0.0086 0.0795
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Schistosoma mansoni hypothetical protein 0.0174 0.0614 0.1153
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0019 0.0017 0.0039
Mycobacterium ulcerans putative regulatory protein 0.0072 0.0221 0.0806
Schistosoma mansoni acetylcholinesterase 0.0107 0.0357 0.0668
Echinococcus multilocularis 0.0039 0.0094 0.0173
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0339 0.0937
Echinococcus multilocularis dro:myosuppressin receptor 0.0055 0.0154 0.0287
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0055 0.0154 0.0287
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Loa Loa (eye worm) hypothetical protein 0.0107 0.0357 0.1034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0154 0.0287
Echinococcus granulosus alpha 1A adrenergic receptor 0.0055 0.0154 0.0287
Plasmodium vivax JmjC domain containing protein 0.0025 0.0038 0.0109
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0004 0.0005
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0119 0.0116
Loa Loa (eye worm) hypothetical protein 0.0327 0.1202 0.3504
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0027 0.0047
Echinococcus granulosus neuropeptides capa receptor 0.0055 0.0154 0.0287
Trichomonas vaginalis esterase, putative 0.0036 0.008 0.0217
Plasmodium falciparum transporter, putative 0.0026 0.0044 0.0115
Onchocerca volvulus 0.0153 0.0533 0.1471
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0017 0.0028
Mycobacterium tuberculosis Conserved protein 0.0036 0.008 0.0219
Leishmania major cathepsin L-like protease 0.0063 0.0186 0.0183
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0186 0.0183
Schistosoma mansoni neuropeptide receptor 0.0055 0.0154 0.0287
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1919 0.7322 0.7322
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0007 0.0013
Brugia malayi glutathione reductase 0.0906 0.3427 1
Leishmania major calcium channel protein, putative,ion transporter, putative 0.012 0.0405 0.0402
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0107 0.0357 0.1004
Loa Loa (eye worm) hypothetical protein 0.0156 0.0543 0.1578
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0154 0.0287
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0028 0.0071
Echinococcus multilocularis neuropeptides capa receptor 0.0055 0.0154 0.0287
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0042 0.004
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0107 0.0357 0.1004
Echinococcus multilocularis sex peptide receptor 0.0055 0.0154 0.0287
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0055 0.0154 0.0287
Brugia malayi Serotonin receptor 0.0521 0.1947 0.5678
Loa Loa (eye worm) hypothetical protein 0.0636 0.2387 0.6963
Echinococcus granulosus neuropeptide FF receptor 2 0.0055 0.0154 0.0287
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0049 0.0131 0.0375
Mycobacterium leprae conserved hypothetical protein 0.0036 0.008 0.0219
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0007 0.001
Brugia malayi Cytochrome P450 family protein 0.0056 0.0161 0.0462
Echinococcus granulosus hypothetical protein 0.0019 0.0017 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0041 0.0108
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0014
Echinococcus multilocularis 6 phosphofructokinase 0.0106 0.0352 0.066
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0039 0.0094 0.0336
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0084 0.0082
Schistosoma mansoni loxhd1 0.0156 0.0543 0.102
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0017 0.0051
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.0016 0.0003 0.0001
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0352 0.3362
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0186 0.0183
Leishmania major inositol polyphosphate 1-phosphatase, putative 0.0016 0.0003 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0038 0.0104
Schistosoma mansoni neuropeptide receptor 0.0055 0.0154 0.0287
Schistosoma mansoni biogenic amine (5HT) receptor 0.0178 0.0629 0.1182
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1041 0.2886
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0014
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0039 0.0094 0.0336
Brugia malayi jmjC domain containing protein 0.0151 0.0523 0.152
Leishmania major dehydrogenase-like protein 0.0019 0.0017 0.0015
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0186 0.0183
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0057 0.016
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0029 0.0057 0.0158
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0186 0.0183
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0161 0.0158
Schistosoma mansoni hypothetical protein 0.0016 0.0003 0.0002
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.012 0.0405 0.0759
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0043
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0191 0.0677 0.6499
Trypanosoma brucei protein kinase, putative 0.0103 0.0339 0.0337
Brugia malayi TAR-binding protein 0.0065 0.0194 0.056
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0045 0.0042
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Mycobacterium ulcerans dehydrogenase 0.0019 0.0017 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0186 0.0183
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0007 0.0036
Loa Loa (eye worm) hypothetical protein 0.0107 0.0357 0.1034
Schistosoma mansoni alpha-1 adrenergic receptor 0.0055 0.0154 0.0287
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0055 0.0154 0.0287
Brugia malayi hypothetical protein 0.0055 0.0154 0.0444
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0035 0.0079 0.0145
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0025 0.0038 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0041 0.0108
Loa Loa (eye worm) hypothetical protein 0.0636 0.2387 0.6963
Brugia malayi Carboxylesterase family protein 0.0107 0.0357 0.1034
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0083 0.0081
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Plasmodium falciparum glutathione reductase 0.0719 0.2708 0.7899
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0004 0.0003
Echinococcus multilocularis GPCR, family 2 0.0016 0.0006 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0017 0.0048
Onchocerca volvulus 0.02 0.0713 0.1972
Plasmodium vivax vivapain-2 0.0017 0.0007 0.0019
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0041 0.0108
Trichomonas vaginalis mercuric reductase, putative 0.0719 0.2708 0.7522
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.0043
Brugia malayi Carboxylesterase family protein 0.0636 0.2387 0.6963
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0054 0.0143
Echinococcus granulosus sodium channel protein 0.012 0.0405 0.0759
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0154 0.0287
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0006
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0019 0.0017 0.0015
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0191 0.0677 0.1971
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.005
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0191 0.0677 0.1877
Onchocerca volvulus 0.003 0.0059 0.0154
Brugia malayi hypothetical protein 0.0019 0.0017 0.0043
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0039 0.0094 0.0336
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0019 0.0017 0.0015
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Schistosoma mansoni amine GPCR 0.0559 0.2091 0.3939
Echinococcus multilocularis phd:f box containing protein 0.0025 0.0038 0.0067
Mycobacterium ulcerans NADH dehydrogenase 0.0191 0.0677 0.2492
Schistosoma mansoni BC026374 protein (S09 family) 0.0107 0.0357 0.0668
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0228
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0191 0.0677 0.1971
Echinococcus multilocularis carboxylesterase 5A 0.0636 0.2387 0.4498
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0719 0.2708 0.5104
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0019 0.0017 0.0015
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0017 0.0028
Brugia malayi Dopamine receptor 0.0055 0.0154 0.0444
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0402 0.149 0.4227
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0119 0.0116
Onchocerca volvulus 0.0017 0.0007 0.001
Echinococcus granulosus g-protein coupled receptor 0.0055 0.0154 0.0287
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0014
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0028
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0017 0.0015
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.012 0.0404 0.118
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0352 0.1021
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0719 0.2708 0.5104
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0042 0.0122
Loa Loa (eye worm) cytochrome P450 0.0039 0.0094 0.0268
Brugia malayi hypothetical protein 0.0055 0.0154 0.0444
Schistosoma mansoni hypothetical protein 0.0037 0.0086 0.0158
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0049 0.0131 0.0242
Schistosoma mansoni intermediate filament proteins 0.0055 0.0155 0.0289
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0194 0.0362
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0013
Echinococcus granulosus jun protein 0.0255 0.0923 0.1737
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0013
Plasmodium vivax SET domain protein, putative 0.012 0.0404 0.1178
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0255 0.0923 0.1737
Leishmania major cytochrome p450-like protein 0.0056 0.0161 0.0158
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0019 0.0017 0.0051
Loa Loa (eye worm) hypothetical protein 0.0054 0.0151 0.0435
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0103 0.0339 0.0337
Echinococcus granulosus hypothetical protein 0.0019 0.0017 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0131 0.0447 0.0839
Echinococcus granulosus steroid dehydrogenase 0.0019 0.0017 0.0028
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0148 0.0514 0.1422
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0719 0.2708 0.5104
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0007 0.0009
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.008 0.0216
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0086 0.0158
Schistosoma mansoni neuropeptide receptor 0.0055 0.0154 0.0287
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0155 0.0447
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0719 0.2708 0.7901
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0191 0.0677 0.1916
Echinococcus multilocularis nuclear factor of activated T cells 5 0.015 0.0522 0.098
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0155 0.0447
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0013
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0191 0.0677 0.2454
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0178 0.0629 0.1829
Brugia malayi hypothetical protein 0.02 0.0713 0.2074
Mycobacterium tuberculosis Conserved protein 0.0036 0.008 0.0219
Entamoeba histolytica hypothetical protein, conserved 0.0019 0.0017 0.0133
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0039
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0041 0.0108
Echinococcus granulosus para nitrobenzyl esterase 0.0107 0.0357 0.0668
Loa Loa (eye worm) hypothetical protein 0.0029 0.0057 0.0158
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0019 0.0017 0.0028
Echinococcus granulosus hyperpolarization activated cyclic 0.0018 0.0014 0.0021
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0043
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0019 0.0017 0.0015
Giardia lamblia Hypothetical protein 0.0019 0.0017 0.0051
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0186 0.0183
Onchocerca volvulus 0.0055 0.0154 0.042
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0191 0.0677 0.1877
Trichomonas vaginalis apoptosis inducing factor, putative 0.0191 0.0677 0.1877
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0019 0.0017 0.0015
Entamoeba histolytica cysteine protease, putative 0.0017 0.0007 0.0036
Brugia malayi Death domain containing protein 0.0029 0.0057 0.0158
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Brugia malayi intermediate filament protein 0.0055 0.0155 0.0447
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Brugia malayi Inositol monophosphatase family protein 0.0016 0.0003 0.0003
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0179 0.0631 0.1185
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0528 0.1974 0.5758
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0004 0.0003
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0025 0.0041 0.0139
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0352 0.3362
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0107 0.0357 0.0668
Onchocerca volvulus 0.0107 0.0357 0.0982
Mycobacterium tuberculosis Possible oxidoreductase 0.0019 0.0017 0.0039
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0119 0.0116
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.001 0.0015
Schistosoma mansoni glutamate synthase 0.0191 0.0677 0.1273
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0191 0.0677 0.1877
Echinococcus granulosus oxidoreductase 0.0019 0.0017 0.0028
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0191 0.0677 0.1977
Echinococcus multilocularis orexin receptor type 2 0.0055 0.0154 0.0287
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.0047 0.0085
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Echinococcus granulosus nuclear factor of activated T cells 5 0.015 0.0522 0.098
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0041 0.0039
Mycobacterium leprae putative cytochrome p450 0.0039 0.0094 0.0258
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.095 0.2634
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0339 0.0636
Brugia malayi Cytochrome P450 family protein 0.0039 0.0094 0.0268
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0191 0.0677 0.1975
Echinococcus multilocularis cysteine protease 0.0017 0.0007 0.0009
Onchocerca volvulus 0.0019 0.0017 0.0038
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0018 0.0014 0.0021
Brugia malayi Protein kinase domain containing protein 0.003 0.006 0.0169
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0604 0.1672
Onchocerca volvulus 0.0055 0.0155 0.0422
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.0479 0.1353
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.009 0.0244
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0019 0.0017 0.005
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0191 0.0677 0.1877
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0019 0.0017 0.0015
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.008 0.0228
Schistosoma mansoni amine GPCR 0.0055 0.0154 0.0287
Plasmodium falciparum ferrodoxin reductase-like protein 0.0191 0.0677 0.1967
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0013
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0019 0.0017 0.005
Brugia malayi sulfakinin receptor protein 0.0055 0.0154 0.0444
Brugia malayi Dopamine receptor protein 1 0.0055 0.0154 0.0444
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0053 0.0148
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0039 0.0094 0.0336
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0044 0.0125
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0007 0.001
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0019 0.0017 0.0041
Brugia malayi hypothetical protein 0.0478 0.178 0.5191
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0301 0.0873
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0028
Onchocerca volvulus 0.0055 0.0154 0.042
Loa Loa (eye worm) hepatopoietin HPO2 0.0035 0.0079 0.0225
Giardia lamblia Fructose-bisphosphate aldolase 0.0285 0.1041 0.3834
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0166 0.0477
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0195 0.0193
Leishmania major hypothetical protein, conserved 0.0025 0.0038 0.0036
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Echinococcus multilocularis allatostatin A receptor 0.0055 0.0154 0.0287
Echinococcus granulosus serotonin receptor 0.0055 0.0154 0.0287
Brugia malayi jmjC domain containing protein 0.0025 0.0038 0.0104
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.0014 0.0021
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0106 0.0352 0.0991
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0039 0.0094 0.0258
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0039 0.0094 0.0258
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0119 0.034
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0028
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.009 0.0165
Chlamydia trachomatis thioredoxin reductase 0.0191 0.0677 0.2492
Onchocerca volvulus Neuropeptide F receptor homolog 0.0055 0.0154 0.042
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0019 0.0017 0.0015
Schistosoma mansoni carbonyl reductase 0.0019 0.0017 0.0028
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.0154 0.0287
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0191 0.0677 0.1971
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0026 0.0044 0.0078
Echinococcus granulosus GPCR family 2 0.0016 0.0006 0.0006
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0039 0.0094 0.0336
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0016 0.0003 0.0003
Plasmodium vivax vivapain-2 0.0017 0.0007 0.0019
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0029 0.0057 0.0102
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0148 0.0514 0.1846
Schistosoma mansoni single-minded 0.0098 0.0319 0.0597
Echinococcus granulosus microtubule associated protein 2 0.1394 0.5304 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0054 0.0143
Echinococcus granulosus Polycystic kidney disease protein 0.0156 0.0543 0.102
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Trypanosoma cruzi hypothetical protein, conserved 0.0191 0.0677 0.0675
Schistosoma mansoni netrin receptor unc5 0.0029 0.0057 0.0102
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0931 0.3521 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0191 0.0677 0.0675
Loa Loa (eye worm) fibroinase 0.0017 0.0007 0.0014
Loa Loa (eye worm) ctsf protein 0.0017 0.0007 0.0014
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0228
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0191 0.0677 0.1273
Onchocerca volvulus 0.0026 0.0044 0.0112
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0106 0.0352 0.0991
Schistosoma mansoni opsin-like receptor 0.0055 0.0154 0.0287
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0054 0.0157
Schistosoma mansoni carbonyl reductase 0.0019 0.0017 0.0028
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0116
Giardia lamblia Thioredoxin reductase 0.0191 0.0677 0.2492
Mycobacterium leprae Conserved hypothetical protein 0.0039 0.0094 0.0258
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0017 0.0051
Schistosoma mansoni hypothetical protein 0.0029 0.0057 0.0102
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.012
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.1041 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0151 0.0523 0.0982
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.008 0.0078
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0044 0.0127
Onchocerca volvulus 0.0036 0.008 0.0214
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Schistosoma mansoni lamin 0.0055 0.0155 0.0289
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0172 0.0479
Echinococcus multilocularis g protein coupled receptor 0.0055 0.0154 0.0287
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0191 0.0677 0.1975
Echinococcus multilocularis para nitrobenzyl esterase 0.0107 0.0357 0.0668
Echinococcus multilocularis survival motor neuron protein 1 0.0478 0.178 0.3354
Trypanosoma cruzi hypothetical protein, conserved 0.0191 0.0677 0.0675
Echinococcus multilocularis lipoxygenase domain containing protein 0.0156 0.0543 0.102
Schistosoma mansoni survival motor neuron protein 0.0097 0.0318 0.0596
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0074 0.0199
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0191 0.0677 0.2454
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Trypanosoma brucei trypanothione reductase 0.0906 0.3427 0.3426
Echinococcus granulosus neuropeptide Y receptor 0.0055 0.0154 0.0287
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0161 0.0158
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Plasmodium falciparum JmjC domain-containing protein, putative 0.0025 0.0038 0.0098
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.014 0.0401
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0019 0.0017 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0228
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0007 0.0005
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.009 0.0246
Echinococcus multilocularis conserved hypothetical protein 0.07 0.2633 0.4962
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0043
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0006 0.0006
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0017 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.009 0.0245
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0074 0.0216
Brugia malayi Augmenter of liver regeneration 0.0035 0.0079 0.0225
Brugia malayi Dehydrogenases, short chain protein 2 0.0019 0.0017 0.0043
Echinococcus multilocularis g protein coupled receptor 0.0055 0.0154 0.0287
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0119 0.1112
Brugia malayi Bromodomain containing protein 0.0028 0.0053 0.0148
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0084 0.0238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0038 0.01
Loa Loa (eye worm) hypothetical protein 0.0025 0.0038 0.0104
Onchocerca volvulus 0.0019 0.0017 0.0038
Echinococcus granulosus g protein coupled receptor 0.0055 0.0154 0.0287
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0191 0.0677 0.2454
Mycobacterium ulcerans carveol-like dehydrogenase 0.0019 0.0017 0.0051
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0044 0.0127
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0017 0.0028
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0195 0.0364
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0255 0.0923 0.1737
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0007 0.0036
Leishmania major trypanothione reductase 0.0906 0.3427 0.3426
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.008 0.0219
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0186 0.0183
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0054 0.0143
Schistosoma mansoni ap endonuclease 0.0038 0.009 0.0165
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0186 0.0183
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0301 0.0564
Echinococcus granulosus neuropeptide s receptor 0.0055 0.0154 0.0287
Echinococcus multilocularis conserved hypothetical protein 0.0019 0.0017 0.0028
Leishmania major cathepsin L-like protease 0.0017 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0191 0.0677 0.197
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0084 0.0082
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0017 0.0015
Onchocerca volvulus 0.0055 0.0154 0.042
Schistosoma mansoni neuropeptide F-like receptor 0.0055 0.0154 0.0287
Schistosoma mansoni sulfide quinone reductase 0.0191 0.0677 0.1273
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.0154 0.0287
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2199 0.8396 0.8396
Brugia malayi hypothetical protein 0.0151 0.0523 0.1519
Echinococcus multilocularis serotonin transporter 0.0153 0.0533 0.1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0013
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0153 0.0533 0.1548
Leishmania major pteridine reductase 1 0.0019 0.0017 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0084 0.0227
Onchocerca volvulus 0.0055 0.0154 0.042
Treponema pallidum oxidoreductase 0.0191 0.0677 0.2349
Echinococcus multilocularis BC026374 protein (S09 family) 0.0107 0.0357 0.0668
Leishmania major protein kinase, putative 0.0031 0.0064 0.0062
Mycobacterium ulcerans oxidoreductase 0.0019 0.0017 0.0051
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0191 0.0677 0.1977
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0019 0.0017 0.0051
Brugia malayi Doublecortin family protein 0.0156 0.0543 0.1578
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0055 0.0154 0.0287
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0028
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0028 0.0048
Loa Loa (eye worm) cysteine protease 0.0017 0.0007 0.0014
Echinococcus granulosus dro:myosuppressin receptor 0.0055 0.0154 0.0287
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.009 0.032
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0191 0.0677 0.0675
Schistosoma mansoni hypothetical protein 0.0191 0.0677 0.1273
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0604 0.1672
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.009 0.0242
Echinococcus multilocularis netrin receptor unc 5 0.0029 0.0057 0.0102
Brugia malayi hypothetical protein 0.0055 0.0154 0.0444
Trypanosoma brucei C-8 sterol isomerase, putative 0.0373 0.1379 0.1377
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.012
Schistosoma mansoni amine GPCR 0.0055 0.0154 0.0287
Echinococcus multilocularis JmjC domain containing protein 4 0.0025 0.0038 0.0067
Onchocerca volvulus 0.0017 0.0007 0.001
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0044 0.012
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0084 0.0154
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0191 0.0677 0.0675
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0048 0.0128
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0027 0.0047
Leishmania major C-8 sterol isomerase-like protein 0.0373 0.1379 0.1377
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1041 0.2886
Echinococcus granulosus orexin receptor type 2 0.0055 0.0154 0.0287
Entamoeba histolytica disulphide oxidoreductase, putative 0.0191 0.0677 0.6499
Brugia malayi G-protein coupled receptor 0.0055 0.0154 0.0444
Loa Loa (eye worm) solute carrier family 6 member 4 0.0153 0.0533 0.1548
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0029 0.0057 0.0102
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.008 0.0219
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0107 0.0357 0.0668
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0016 0.0014
Brugia malayi neuropeptide F receptor 0.0055 0.0154 0.0444
Loa Loa (eye worm) melatonin receptor type 1A 0.0055 0.0154 0.0444
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.095 0.2634
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0719 0.2708 0.7902
Onchocerca volvulus 0.0156 0.0543 0.15
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0191 0.0677 0.1916
Echinococcus granulosus JmjC domain containing protein 4 0.0025 0.0038 0.0067
Plasmodium vivax thioredoxin reductase, putative 0.0906 0.3427 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0154 0.0287
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0017 0.0015
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0301 0.0564
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.017 0.0488
Brugia malayi hypothetical protein 0.0055 0.0154 0.0444
Plasmodium falciparum thioredoxin reductase 0.0906 0.3427 1
Echinococcus multilocularis geminin 0.0174 0.0614 0.1153
Mycobacterium ulcerans dehydrogenase/reductase 0.0019 0.0017 0.0051
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0041 0.0108
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0019 0.0017 0.0039
Brugia malayi hypothetical protein 0.0327 0.1202 0.3504
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.008 0.0219
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0039 0.0094 0.0336
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0191 0.0677 0.0675
Mycobacterium ulcerans oxidoreductase 0.0019 0.0017 0.0051
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0041 0.0108
Onchocerca volvulus 0.0026 0.0044 0.0112
Brugia malayi 6-phosphofructokinase 0.0106 0.0352 0.1022
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0172 0.0623
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0191 0.0677 0.1877
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Onchocerca volvulus 0.0107 0.0357 0.0982
Onchocerca volvulus 0.0055 0.0154 0.042
Schistosoma mansoni disulfide oxidoreductase 0.0191 0.0677 0.1273
Brugia malayi Cathepsin L-like precursor 0.0017 0.0007 0.0014
Schistosoma mansoni polycystin 1-related 0.0156 0.0543 0.102
Loa Loa (eye worm) hypothetical protein 0.0035 0.0078 0.022
Echinococcus multilocularis fmrfamide receptor 0.0055 0.0154 0.0287
Echinococcus multilocularis acetylcholinesterase 0.0636 0.2387 0.4498
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0103 0.0339 0.0337
Entamoeba histolytica thioredoxin reductase, putative 0.0191 0.0677 0.6499
Brugia malayi Carboxylesterase family protein 0.0107 0.0357 0.1034
Plasmodium vivax ferrodoxin reductase, putative 0.0191 0.0677 0.1975
Onchocerca volvulus 0.0055 0.0154 0.042
Brugia malayi hypothetical protein 0.0026 0.0044 0.012
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0019 0.0017 0.0039
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0154 0.0287
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0028
Echinococcus granulosus phd:f box containing protein 0.0025 0.0038 0.0067
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0191 0.0677 0.1273
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.008 0.0217
Leishmania major oxidoreductase-like protein 0.0019 0.0017 0.0015
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0041 0.0108
Brugia malayi hypothetical protein 0.0156 0.0543 0.1578
Onchocerca volvulus 0.0055 0.0154 0.042
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0041 0.0108
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0007 0.0009
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.0479 0.176
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.012
Toxoplasma gondii ABC1 family protein 0.0036 0.008 0.0234
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0191 0.0677 0.6499
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0084 0.0154
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0161
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0039 0.0094 0.0336
Loa Loa (eye worm) hypothetical protein 0.0107 0.0357 0.1034
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Toxoplasma gondii oxidoreductase, putative 0.0019 0.0017 0.005
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0026 0.0044 0.0078
Echinococcus multilocularis lysine specific demethylase 6a 0.0025 0.0038 0.0067
Schistosoma mansoni sodium/chloride dependent transporter 0.0153 0.0533 0.1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1919 0.7322 0.7322
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0191 0.0677 0.1916
Loa Loa (eye worm) programmed cell death 8 0.0191 0.0677 0.1971
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0119 0.0324
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0195 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0007 0.0013
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0019 0.0017 0.0015
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0262 0.095 0.2767
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.0079 0.0077
Onchocerca volvulus 0.0019 0.0017 0.0038
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0017 0.0051
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1041 0.2886
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0013
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0195 0.0364
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0836 0.3156 0.9208
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0019 0.0017 0.005
Plasmodium falciparum thioredoxin reductase 0.0719 0.2708 0.7899
Mycobacterium ulcerans lipase LipD 0.0036 0.008 0.0285
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0038 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0048 0.0126
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0194 0.056
Onchocerca volvulus 0.0097 0.0318 0.0875
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0026 0.0044 0.0078
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0026 0.0044 0.0078
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0028
Toxoplasma gondii thioredoxin reductase 0.0906 0.3427 1
Onchocerca volvulus 0.0055 0.0155 0.0422
Brugia malayi Carboxylesterase family protein 0.0107 0.0357 0.1034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0083 0.0224
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0039 0.0094 0.0336
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.0014 0.0021
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0191 0.0677 0.2492
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0604 0.1672
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0053 0.0153
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0017 0.0028
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0194 0.0362
Schistosoma mansoni phosphatidylserine receptor 0.0025 0.0038 0.0067
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0194 0.0687 0.0685
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0039 0.0094 0.0258
Onchocerca volvulus 0.0019 0.0017 0.0038
Mycobacterium tuberculosis Carboxylesterase LipT 0.0107 0.0357 0.1004
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0894 0.3382 0.6374
Echinococcus multilocularis steroid dehydrogenase 0.0019 0.0017 0.0028
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0017 0.0015
Brugia malayi phosphofructokinase 0.0106 0.0352 0.1021
Leishmania major hypothetical protein, conserved 0.0191 0.0677 0.0675
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0017 0.0015
Echinococcus granulosus neuropeptide Y receptor 0.0055 0.0154 0.0287
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.012
Onchocerca volvulus 0.0036 0.008 0.0214
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0019 0.0017 0.0015
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0044 0.012
Schistosoma mansoni inositol monophosphatase 0.0148 0.0514 0.0965
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0083 0.0224
Echinococcus multilocularis neuropeptide receptor 0.0055 0.0154 0.0287
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0019 0.0017 0.0039
Giardia lamblia Kinase, CMGC MAPK 0.0103 0.0339 0.1242
Echinococcus granulosus jumonji domain containing 1A 0.0025 0.0038 0.0067
Loa Loa (eye worm) hypothetical protein 0.0107 0.0357 0.1034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0007 0.0013
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0103 0.0339 0.0337
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0352 0.0972
Schistosoma mansoni neuropeptide f receptor 76f 0.0055 0.0154 0.0287
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.1041 1
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0195 0.0563
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0018 0.0014 0.0021
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.008 0.0219
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0043
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0017 0.0028
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0006 0.001
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0039 0.0094 0.0258
Onchocerca volvulus 0.0055 0.0154 0.042
Brugia malayi bHLH-PAS transcription factor 0.0072 0.0221 0.0639
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0054 0.0143
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0053 0.0096
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0039 0.0094 0.0258
Echinococcus multilocularis serotonin receptor 0.0178 0.0629 0.1182
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0017 0.0039
Echinococcus granulosus inositol monophosphatase 1 0.0148 0.0514 0.0965
Echinococcus granulosus mitogen activated protein kinase 3 0.0103 0.0339 0.0636
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0054 0.0157
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0055 0.0154 0.042
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Entamoeba histolytica hypothetical protein 0.0037 0.0086 0.0795
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0154 0.0287
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0043
Trypanosoma cruzi short chain dehydrogenase, putative 0.0019 0.0017 0.0015
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0719 0.2708 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.009 0.0088
Leishmania major hypothetical protein, conserved 0.0036 0.008 0.0078
Echinococcus granulosus netrin receptor unc 5 0.0029 0.0057 0.0102
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0039
Loa Loa (eye worm) hypothetical protein 0.0475 0.1768 0.5155
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Leishmania major NADH dehydrogenase, putative 0.0191 0.0677 0.0675
Echinococcus granulosus carboxylesterase 5A 0.0636 0.2387 0.4498
Echinococcus granulosus 6 phosphofructokinase 0.0106 0.0352 0.066
Loa Loa (eye worm) hypothetical protein 0.0151 0.0523 0.1519
Echinococcus granulosus lipoxygenase domain containing protein 0.0156 0.0543 0.102
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0084 0.0082
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0444
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0154 0.0287
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0007 0.0014
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0054 0.0156
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.0154 0.0287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0038 0.01
Trichomonas vaginalis glutamate synthase, putative 0.0191 0.0677 0.1877
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0019 0.0017 0.0015
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0025 0.0038 0.0067
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0154 0.0287
Onchocerca volvulus 0.0055 0.0154 0.042
Trichomonas vaginalis steroid dehydrogenase, putative 0.0019 0.0017 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0007 0.0013
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0055 0.0154 0.0444
Echinococcus granulosus mitogen activated protein kinase 0.0103 0.0339 0.0636
Loa Loa (eye worm) hypothetical protein 0.0107 0.0357 0.1034
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0004 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0017 0.0015
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2199 0.8396 0.8396

Activities

Activity type Activity value Assay description Source Reference
AUC (ADMET) = 116 ng.hr/ml AUC (0 to 6h) in rat at 10 mg/kg, po ChEMBL. 17988864
IC50 (binding) = 35 nM Inhibition of gamma secretase (unknown origin) assessed as membrane Amyloid beta 40 level ChEMBL. 17988864
IC50 (ADMET) = 11.9 uM Inhibition of CYP3A4 (unknown origin) preincubated before 30 mins ChEMBL. 17988864
IC50 (ADMET) = 11.9 uM Inhibition of CYP3A4 (unknown origin) preincubated before 30 mins ChEMBL. 17988864

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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