Detailed information for compound 506105

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 419.51 | Formula: C22H26FNO4S
  • H donors: 2 H acceptors: 3 LogP: 4.73 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC[C@H]([C@@H](C(=O)N[C@H](C(=O)O)Cc1ccc(cc1)OCc1ccc(cc1)F)S)C
  • InChi: 1S/C22H26FNO4S/c1-3-14(2)20(29)21(25)24-19(22(26)27)12-15-6-10-18(11-7-15)28-13-16-4-8-17(23)9-5-16/h4-11,14,19-20,29H,3,12-13H2,1-2H3,(H,24,25)(H,26,27)/t14-,19+,20+/m1/s1
  • InChiKey: KZAYYAIBZWKHEY-UAOJZALGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens membrane metallo-endopeptidase Starlite/ChEMBL References
Homo sapiens angiotensin I converting enzyme Starlite/ChEMBL References
Homo sapiens carboxypeptidase A1 (pancreatic) Starlite/ChEMBL References
Homo sapiens angiotensin I converting enzyme 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Neospora caninum hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) angiotensin-converting enzyme family protein Get druggable targets OG5_131988 All targets in OG5_131988
Mycobacterium ulcerans zinc metalloprotease Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
Onchocerca volvulus Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) peptidase family M13 containing protein Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
Schistosoma japonicum IPR000718,Peptidase M13, neprilysin,domain-containing Get druggable targets OG5_127344 All targets in OG5_127344
Toxoplasma gondii peptidase family M13 protein Get druggable targets OG5_127344 All targets in OG5_127344
Brugia malayi Angiotensin-converting enzyme family protein Get druggable targets OG5_131988 All targets in OG5_131988
Schistosoma japonicum ko:K01415 endothelin-converting enzyme [EC3.4.24.71], putative Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
Mycobacterium leprae probable zinc metalloprotease Get druggable targets OG5_127344 All targets in OG5_127344
Schistosoma mansoni family M13 unassigned peptidase (M13 family) Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
Echinococcus granulosus endothelin converting enzyme 1 Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
Echinococcus multilocularis endothelin converting enzyme 1 Get druggable targets OG5_127344 All targets in OG5_127344
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 Get druggable targets OG5_127344 All targets in OG5_127344
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) peptidase family M13 containing protein Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
Brugia malayi Peptidase family M13 containing protein Get druggable targets OG5_127344 All targets in OG5_127344
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127344 All targets in OG5_127344
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis subfamily M14A unassigned peptidase carboxypeptidase A1 (pancreatic) 419 aa 402 aa 33.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0192 0.0677 0.0674
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0017 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0187 0.0184
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0041 0.0038
Brugia malayi hypothetical protein 0.0055 0.0156 0.0431
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0136 0.0375
Loa Loa (eye worm) hypothetical protein 0.0155 0.0537 0.1503
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0013 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0013
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0005 0.0005
Loa Loa (eye worm) doublecortin family protein 0.0157 0.0543 0.152
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0114 0.038 0.0725
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.009 0.0243
Echinococcus multilocularis neuropeptides capa receptor 0.0055 0.0156 0.0295
Loa Loa (eye worm) ctsf protein 0.0017 0.0008 0.0013
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0085 0.0158
Loa Loa (eye worm) hypothetical protein 0.018 0.0634 0.1776
Brugia malayi Blistered cuticle protein 3 0.007 0.0213 0.0589
Echinococcus granulosus glutamate synthase 0.0192 0.0677 0.1298
Schistosoma mansoni lipoxygenase 0.0688 0.2574 0.4947
Echinococcus granulosus steroid dehydrogenase 0.0019 0.0017 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0013
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0101 0.0332 0.0329
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0019 0.0017 0.0027
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0085 0.0158
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0055 0.0156 0.0431
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0008 0.0043
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0355 0.3372
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0019 0.0017 0.004
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.009 0.0243
Onchocerca volvulus 0.003 0.006 0.0156
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.0958 0.2636
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0355 0.1002
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0078 0.0207
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Mycobacterium ulcerans oxidoreductase 0.0019 0.0017 0.0051
Echinococcus multilocularis conserved hypothetical protein 0.0708 0.2653 0.5099
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.0156 0.0295
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0057 0.0162 0.0588
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0019 0.0017 0.004
Echinococcus multilocularis peregrin 0.0029 0.0054 0.0098
Echinococcus granulosus neuropeptide receptor A26 0.0055 0.0156 0.0295
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0311 0.0867
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2629 1 1
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0424 0.0809
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.004 0.0096 0.0263
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0121 0.0408 0.0779
Echinococcus multilocularis allatostatin A receptor 0.0055 0.0156 0.0295
Brugia malayi hypothetical protein 0.0157 0.0543 0.152
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0156 0.0295
Brugia malayi hypothetical protein 0.0055 0.0156 0.0431
Onchocerca volvulus 0.0055 0.0156 0.0422
Echinococcus multilocularis neuroligin 0.0108 0.0356 0.0679
Echinococcus multilocularis netrin receptor unc 5 0.0029 0.0056 0.0102
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0019 0.0017 0.0027
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0355 0.0991
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0192 0.0677 0.1298
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0054 0.0158
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0055 0.0161
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0174 0.063
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0085 0.0158
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0017 0.004
Onchocerca volvulus 0.0055 0.0154 0.0417
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.01
Mycobacterium ulcerans oxidoreductase 0.0019 0.0017 0.0051
Leishmania major cytochrome p450-like protein 0.004 0.0096 0.0092
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1047 0.2883
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.004 0.0096 0.0263
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0028 0.005 0.0091
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0156 0.0295
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Entamoeba histolytica hypothetical protein 0.0036 0.0084 0.0767
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0055 0.0151
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0045 0.0117
Brugia malayi jmjC domain containing protein 0.0025 0.0039 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0075 0.0199
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.004 0.0096 0.0341
Mycobacterium ulcerans hypothetical protein 0.0192 0.0677 0.2493
Brugia malayi Inositol monophosphatase family protein 0.0016 0.0003 0.0001
Brugia malayi Melatonin receptor type 1A 0.0055 0.0156 0.0431
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0304 0.0579
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0008 0.0009
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0078 0.0277
Onchocerca volvulus Glucosylceramidase homolog 0.0174 0.0609 0.1672
Echinococcus granulosus biogenic amine 5HT receptor 0.018 0.0634 0.1215
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Echinococcus granulosus cytochrome P450 2K1 0.004 0.0096 0.0178
Schistosoma mansoni phd/f-box containing protein 0.0025 0.0039 0.0069
Schistosoma mansoni growth hormone secretagogue receptor 0.0055 0.0156 0.0295
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0192 0.0677 0.192
Mycobacterium tuberculosis Possible oxidoreductase 0.0019 0.0017 0.004
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0054 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.01
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0003
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.009 0.0086
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0179 0.063 0.2317
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0019 0.0017 0.004
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0078 0.0207
Onchocerca volvulus 0.0055 0.0156 0.0422
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0039
Trichomonas vaginalis inositol monophosphatase, putative 0.0016 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.0034 0.0076 0.0139
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0136 0.0375
Brugia malayi hypothetical protein 0.0055 0.0156 0.0431
Mycobacterium leprae putative cytochrome p450 0.004 0.0096 0.0263
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.012 0.0117
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0187 0.0184
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0192 0.0677 0.192
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0085 0.0226
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0192 0.0677 0.2493
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0288 0.1047 1
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.004 0.0096 0.0341
Brugia malayi G-protein coupled receptor 0.0055 0.0156 0.0431
Loa Loa (eye worm) hypothetical protein 0.0314 0.1144 0.3211
Schistosoma mansoni 60S ribosomal protein L21 0.0017 0.0008 0.0009
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.004 0.0096 0.0341
Schistosoma mansoni sulfide quinone reductase 0.0192 0.0677 0.1298
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0192 0.0677 0.1862
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0332 0.0908
Echinococcus multilocularis mitogen activated protein kinase 3 0.0101 0.0332 0.0633
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0039
Brugia malayi Thioredoxin reductase 0.091 0.3424 0.9624
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0019 0.0017 0.0014
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0179 0.063 0.1763
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0029 0.0056 0.0149
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Echinococcus multilocularis sex peptide receptor 0.0055 0.0156 0.0295
Echinococcus multilocularis BC026374 protein (S09 family) 0.0108 0.0356 0.0679
Echinococcus granulosus oxidoreductase 0.0019 0.0017 0.0027
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0019 0.0017 0.0039
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0192 0.0677 0.1298
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0055 0.0143
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0019 0.0017 0.0051
Loa Loa (eye worm) programmed cell death 8 0.0192 0.0677 0.1897
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0192 0.0677 0.0674
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0192 0.0677 0.1897
Schistosoma mansoni carbonyl reductase 0.0019 0.0017 0.0027
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0722 0.2707 0.2705
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0026 0.0045 0.0117
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0722 0.2707 1
Brugia malayi hypothetical protein 0.0055 0.0156 0.0431
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0084 0.0155
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0027
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0008 0.0012
Schistosoma mansoni biogenic amine (5HT) receptor 0.018 0.0634 0.1215
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.004 0.0096 0.0263
Loa Loa (eye worm) hypothetical protein 0.0121 0.0408 0.1139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0062 0.0163
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0019 0.0017 0.0041
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.004
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0192 0.0677 0.192
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0008 0.0009
Echinococcus granulosus G protein coupled receptor 139 0.0055 0.0156 0.0295
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0192 0.0677 0.1971
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0028 0.005 0.0091
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0019 0.0017 0.0014
Loa Loa (eye worm) fibroinase 0.0017 0.0008 0.0013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0056 0.0149
Plasmodium falciparum glutathione reductase 0.0722 0.2707 0.7904
Loa Loa (eye worm) glutathione reductase 0.091 0.3424 0.9624
Leishmania major hypothetical protein, conserved 0.0192 0.0677 0.0674
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0027 0.0045
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0026 0.0045 0.008
Loa Loa (eye worm) G-protein coupled receptor 0.0055 0.0156 0.0431
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0017 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0187 0.0184
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.0077 0.0215
Onchocerca volvulus 0.0055 0.0154 0.0417
Onchocerca volvulus 0.0108 0.0356 0.0974
Leishmania major pteridine reductase 1 0.0019 0.0017 0.0014
Onchocerca volvulus 0.0017 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0327 0.1194 0.3352
Brugia malayi Protein kinase domain containing protein 0.003 0.006 0.0159
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0043 0.004
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0055 0.0156 0.0295
Echinococcus granulosus neuropeptide receptor 0.0055 0.0156 0.0295
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0041 0.0104
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0076 0.0203
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0078 0.0213
Echinococcus multilocularis acetylcholinesterase 0.0638 0.2383 0.458
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0192 0.0677 0.1298
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0055 0.0156 0.0295
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Echinococcus granulosus jumonji domain containing protein 0.004 0.0097 0.0181
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0019 0.0017 0.0027
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0378 0.139 0.1387
Toxoplasma gondii oxidoreductase, putative 0.0019 0.0017 0.0041
Brugia malayi Carboxylesterase family protein 0.0638 0.2383 0.6696
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0403 0.1485 0.422
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.0304 0.0847
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0005 0.0002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0019 0.0017 0.0041
Trichomonas vaginalis inositol monophosphatase, putative 0.0148 0.0511 0.1402
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0155 0.0537 0.1503
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0035 0.0077 0.0142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0187 0.0184
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0191 0.0361
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0044 0.0041
Schistosoma mansoni sodium/chloride dependent transporter 0.0155 0.0537 0.1028
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0027
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0192 0.0677 0.6458
Loa Loa (eye worm) beta-lactamase 0.0035 0.0078 0.0211
Mycobacterium ulcerans glutamate synthase subunit beta 0.0192 0.0677 0.2493
Entamoeba histolytica short chain dehydrogenase family protein 0.0019 0.0017 0.0133
Schistosoma mansoni amine GPCR 0.0055 0.0156 0.0295
Leishmania major cytochrome p450-like protein 0.0057 0.0162 0.0159
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0154 0.0426
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0041 0.0073
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0192 0.0677 0.1967
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0045 0.008
Echinococcus multilocularis para nitrobenzyl esterase 0.0108 0.0356 0.0679
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0078 0.0075
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0355 0.0678
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0041 0.0104
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0017 0.0027
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0055 0.0156 0.0431
Onchocerca volvulus 0.0019 0.0017 0.0038
Onchocerca volvulus 0.0019 0.0017 0.0038
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0722 0.2707 1
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0192 0.0677 0.192
Onchocerca volvulus 0.0152 0.0527 0.1445
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0017 0.0014
Brugia malayi Cytochrome P450 family protein 0.0057 0.0162 0.0448
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.004 0.0096 0.0263
Schistosoma mansoni hypothetical protein 0.0206 0.0732 0.1402
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0192 0.0677 0.0674
Toxoplasma gondii cathepsin CPL 0.0017 0.0008 0.0013
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0179 0.063 0.1206
Schistosoma mansoni jumonji domain containing protein 0.0133 0.0453 0.0865
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Loa Loa (eye worm) carboxylesterase 0.0108 0.0356 0.0993
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Toxoplasma gondii carbonyl reductase 1, putative 0.0019 0.0017 0.0041
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0008 0.0012
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.004 0.0096 0.0341
Brugia malayi larval opioid receptor 0.0055 0.0156 0.0431
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0722 0.2707 0.7907
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.0077 0.0074
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0018 0.0013 0.002
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0148 0.0511 0.4861
Loa Loa (eye worm) hypothetical protein 0.0026 0.0045 0.0117
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0355 0.0678
Schistosoma mansoni amine GPCR 0.0565 0.2107 0.4048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.018 0.0634 0.1776
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0008 0.0043
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0019 0.0017 0.0133
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0174 0.0328
Loa Loa (eye worm) G-protein coupled receptor 0.0055 0.0156 0.0431
Plasmodium vivax ferrodoxin reductase, putative 0.0192 0.0677 0.1979
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0192 0.0677 0.1862
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0017 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0025 0.0039 0.0069
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Brugia malayi 6-phosphofructokinase 0.0108 0.0355 0.0991
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0355 0.0352
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0027
Toxoplasma gondii oxidoreductase, putative 0.0019 0.0017 0.0041
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0041 0.0104
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0019 0.0017 0.0051
Echinococcus granulosus neuropeptide receptor 0.0055 0.0156 0.0295
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0075 0.0199
Mycobacterium leprae probable zinc metalloprotease 0.0114 0.038 0.1073
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0017 0.0014
Brugia malayi Dehydrogenases, short chain protein 30 0.0019 0.0017 0.004
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0045 0.008
Onchocerca volvulus 0.0019 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0035 0.0078 0.0211
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Loa Loa (eye worm) RecQ helicase 0.0022 0.0027 0.0066
Echinococcus multilocularis g protein coupled receptor 0.0055 0.0156 0.0295
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0192 0.0677 0.1862
Trichomonas vaginalis apoptosis inducing factor, putative 0.0192 0.0677 0.1862
Echinococcus multilocularis chromobox protein 1 0.0069 0.0208 0.0393
Mycobacterium ulcerans dehydrogenase 0.0192 0.0677 0.2493
Loa Loa (eye worm) hypothetical protein 0.0026 0.0043 0.0112
Echinococcus multilocularis carboxylesterase 5A 0.0638 0.2383 0.458
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0019 0.0017 0.0036
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0058 0.0164 0.031
Brugia malayi hypothetical protein 0.0019 0.0017 0.004
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0722 0.2707 0.7907
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.004
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0121 0.0408 0.0779
Loa Loa (eye worm) hypothetical protein 0.0638 0.2383 0.6696
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0084 0.0224
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0192 0.0677 0.2454
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0424 0.0809
Onchocerca volvulus 0.0056 0.016 0.0433
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0688 0.2574 0.4947
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0078 0.0213
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0005 0.0005
Schistosoma mansoni carbonyl reductase 0.0019 0.0017 0.0027
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.012 0.0117
Leishmania major hypothetical protein, conserved 0.0019 0.0017 0.0014
Leishmania major oxidoreductase-like protein 0.0019 0.0017 0.0014
Onchocerca volvulus 0.0017 0.0008 0.0012
Trichomonas vaginalis esterase, putative 0.0035 0.0078 0.0207
Giardia lamblia Glutamate synthase 0.0192 0.0677 0.2493
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0027 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0013
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0192 0.0677 0.2454
Echinococcus multilocularis lysine specific demethylase 5A 0.0093 0.03 0.0571
Loa Loa (eye worm) cytochrome P450 family protein 0.0057 0.0162 0.0448
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0191 0.1796
Brugia malayi bZIP transcription factor family protein 0.0253 0.0913 0.2561
Brugia malayi RNA recognition motif domain containing protein 0.0125 0.0424 0.1183
Echinococcus granulosus orexin receptor type 2 0.0055 0.0156 0.0295
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0265 0.0958 0.2686
Onchocerca volvulus 0.0017 0.0008 0.0012
Onchocerca volvulus 0.0019 0.0017 0.0038
Onchocerca volvulus Sepiapterin reductase homolog 0.0019 0.0017 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.0099
Brugia malayi RNA binding protein 0.0125 0.0424 0.1183
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0017 0.0014
Brugia malayi hypothetical protein 0.0017 0.0008 0.0013
Echinococcus multilocularis orexin receptor type 2 0.0055 0.0156 0.0295
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.0156 0.0295
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0019 0.0017 0.0027
Echinococcus multilocularis survival motor neuron protein 1 0.0471 0.1745 0.3352
Echinococcus multilocularis musashi 0.0055 0.0154 0.0291
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0174 0.063
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.004 0.0096 0.0341
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0722 0.2707 1
Echinococcus granulosus death domain containing protein 0.0029 0.0056 0.0102
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.012 0.0117
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0108 0.0356 0.0975
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0017 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.012 0.0324
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1047 0.2883
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0179 0.063 0.1784
Brugia malayi G-protein coupled receptor 0.0055 0.0156 0.0431
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0424 0.0809
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0191 0.0528
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0075 0.0199
Onchocerca volvulus 0.0072 0.022 0.0598
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0013
Echinococcus multilocularis chromobox protein 1 0.0069 0.0208 0.0393
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0078 0.0207
Echinococcus multilocularis serotonin transporter 0.0155 0.0537 0.1028
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0027 0.0066
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0355 0.0972
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.004 0.0096 0.0263
Echinococcus multilocularis hyperpolarization activated cyclic 0.0018 0.0013 0.002
Brugia malayi dehydrogenases, short chain protein 9 0.0019 0.0017 0.004
Schistosoma mansoni sodium-dependent amino acid transporter 0.0026 0.0045 0.008
Brugia malayi Cathepsin L-like precursor 0.0017 0.0008 0.0013
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0191 0.0361
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0026 0.0045 0.0117
Mycobacterium ulcerans putative regulatory protein 0.0072 0.022 0.0801
Plasmodium vivax vivapain-2 0.0017 0.0008 0.0023
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0008 0.0009
Echinococcus granulosus BC026374 protein S09 family 0.0108 0.0356 0.0679
Brugia malayi chromobox protein homolog 3 0.0039 0.0092 0.0249
Schistosoma mansoni rab6-interacting 0.0157 0.0543 0.104
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0039
Echinococcus granulosus histone lysine methyltransferase setb 0.0121 0.0408 0.0779
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0017 0.0027
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0092 0.0244
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0026 0.0045 0.0117
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0026 0.0045 0.008
Echinococcus granulosus carboxylesterase 5A 0.0638 0.2383 0.458
Brugia malayi hypothetical protein 0.0055 0.0156 0.0431
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0078 0.0211
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0187 0.0184
Echinococcus granulosus sodium and chloride dependent glycine 0.0026 0.0045 0.008
Plasmodium falciparum thioredoxin reductase 0.0722 0.2707 0.7904
Schistosoma mansoni opsin-like receptor 0.0055 0.0156 0.0295
Echinococcus multilocularis cysteine protease 0.0017 0.0008 0.0009
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0017 0.0027
Schistosoma mansoni jun-related protein 0.0206 0.0732 0.1402
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0019 0.0017 0.0014
Treponema pallidum NADH oxidase 0.0722 0.2707 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Brugia malayi jmjC domain containing protein 0.0093 0.03 0.0834
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0355 0.0972
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0055 0.0161
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0192 0.0677 0.6458
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0027
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0108 0.0356 0.1004
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0019 0.0017 0.0038
Echinococcus granulosus retinol dehydrogenase 11 0.0019 0.0017 0.0027
Echinococcus granulosus single minded 2 0.0076 0.0233 0.0442
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0008 0.0013
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0017 0.0014
Echinococcus multilocularis sodium channel protein 0.0121 0.0408 0.0779
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.004 0.0096 0.0263
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0101 0.0332 0.0925
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0179 0.063 0.2317
Leishmania major short chain dehydrogenase, putative 0.0019 0.0017 0.0014
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0055 0.0156 0.0431
Schistosoma mansoni histamine h1 receptor 0.0055 0.0156 0.0295
Mycobacterium ulcerans zinc metalloprotease 0.0114 0.038 0.1393
Schistosoma mansoni intermediate filament proteins 0.0055 0.0154 0.0291
Schistosoma mansoni neuropeptide f receptor 76f 0.0055 0.0156 0.0295
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0355 0.1302
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.0141 0.0266
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.0066
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0108
Brugia malayi beta-lactamase 0.0035 0.0078 0.0211
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0148 0.0511 0.1877
Echinococcus granulosus subfamily M14A unassigned peptidase 0.0068 0.0205 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0008 0.0013
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.004 0.0096 0.0341
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Echinococcus granulosus cathepsin l1 0.0017 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0121 0.0408 0.1183
Onchocerca volvulus 0.0017 0.0008 0.0012
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.009 0.0261
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0055 0.0156 0.0295
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0156 0.0295
Loa Loa (eye worm) carboxylesterase 0.0638 0.2383 0.6696
Brugia malayi hypothetical protein 0.0055 0.0156 0.0431
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0531 0.1974 0.5544
Brugia malayi AKH receptor 0.0055 0.0156 0.0431
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0208 0.0575
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0208 0.0565
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1929 0.7322 0.7321
Brugia malayi Death domain containing protein 0.0029 0.0056 0.0149
Loa Loa (eye worm) solute carrier family 6 member 4 0.0155 0.0537 0.1503
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0085 0.0783
Entamoeba histolytica hypothetical protein 0.0036 0.0084 0.0767
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0055 0.0156 0.0295
Loa Loa (eye worm) hypothetical protein 0.0378 0.139 0.3901
Onchocerca volvulus 0.0026 0.0045 0.0114
Schistosoma mansoni hypothetical protein 0.0055 0.0156 0.0295
Toxoplasma gondii hypothetical protein 0.0026 0.0045 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0013
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0039 0.0036
Loa Loa (eye worm) TYRA-2 protein 0.0055 0.0156 0.0431
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0055 0.0151
Brugia malayi Dopamine receptor 0.0055 0.0156 0.0431
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0133 0.0451 0.1276
Brugia malayi Pre-SET motif family protein 0.0121 0.0408 0.1139
Echinococcus granulosus lipoxygenase domain containing protein 0.0157 0.0543 0.104
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0013 0.002
Leishmania major trypanothione reductase 0.091 0.3424 0.3421
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.009 0.0086
Echinococcus multilocularis retinol dehydrogenase 13 0.0019 0.0017 0.0027
Trichomonas vaginalis glutamate synthase, putative 0.0192 0.0677 0.1862
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.221 0.8396 0.8395
Onchocerca volvulus 0.0155 0.0537 0.1474
Loa Loa (eye worm) serotonin transporter b 0.0155 0.0537 0.1503
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0192 0.0677 0.1979
Brugia malayi Serotonin receptor 0.0055 0.0156 0.0431
Loa Loa (eye worm) hypothetical protein 0.0056 0.016 0.0442
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0027 0.0065
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0055 0.0156 0.0295
Loa Loa (eye worm) hypothetical protein 0.0086 0.0274 0.0762
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0253 0.0913 0.1751
Onchocerca volvulus 0.0019 0.0017 0.0038
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0019 0.0017 0.0027
Loa Loa (eye worm) dehydrogenase 0.0019 0.0017 0.004
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0054 0.0098
Trypanosoma cruzi hypothetical protein, conserved 0.0192 0.0677 0.0674
Schistosoma mansoni lamin 0.0055 0.0154 0.0291
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.004
Onchocerca volvulus 0.0035 0.0078 0.0206
Schistosoma mansoni hypothetical protein 0.004 0.0096 0.0178
Brugia malayi MAP kinase sur-1 0.0101 0.0332 0.0925
Echinococcus multilocularis transfer RNA-Lys 0.0072 0.022 0.0417
Entamoeba histolytica hypothetical protein 0.0036 0.0084 0.0767
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.091 0.3424 0.9741
Brugia malayi Heterochromatin protein 1 0.0069 0.0208 0.0575
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0075 0.0199
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.004 0.0096 0.0341
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0174 0.0485
Schistosoma mansoni hypothetical protein 0.0172 0.0601 0.115
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.004 0.0096 0.0341
Schistosoma mansoni neuropeptide receptor 0.0055 0.0156 0.0295
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0029
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0192 0.0677 0.0674
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0192 0.0677 0.1979
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0054 0.0098
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0045 0.0117
Brugia malayi SET domain containing protein 0.0016 0.0004 0.0003
Onchocerca volvulus Alhambra homolog 0.0029 0.0054 0.014
Brugia malayi putative neuropeptide receptor NPR1 0.0055 0.0156 0.0431
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0005 0.0003
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0403 0.1485 0.422
Echinococcus multilocularis neuropeptide Y receptor 0.0055 0.0156 0.0295
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0085 0.0081
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0192 0.0677 0.1298
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0039 0.01
Onchocerca volvulus 0.0019 0.0017 0.0038
Onchocerca volvulus 0.0157 0.0543 0.1491
Brugia malayi jmjC domain containing protein 0.0025 0.0039 0.01
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Echinococcus granulosus neuropeptides capa receptor 0.0055 0.0156 0.0295
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.016 0.0557 0.1557
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0078 0.0144
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0192 0.0677 0.192
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0355 0.0352
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0039
Toxoplasma gondii ABC1 family protein 0.0035 0.0078 0.0219
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Onchocerca volvulus 0.0108 0.0356 0.0974
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0192 0.0677 0.0674
Loa Loa (eye worm) hypothetical protein 0.0157 0.0543 0.152
Echinococcus granulosus neuropeptides capa receptor 0.0055 0.0156 0.0295
Loa Loa (eye worm) hypothetical protein 0.0065 0.0192 0.0531
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0055 0.0156 0.0295
Plasmodium falciparum thioredoxin reductase 0.091 0.3424 1
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0192 0.0677 0.0674
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0017 0.004
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0084 0.0155
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0156 0.0295
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0005 0.0003
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0152 0.0527 0.1008
Loa Loa (eye worm) hypoxia-induced factor 1 0.0302 0.1097 0.3079
Brugia malayi peptidase family M13 containing protein 0.0028 0.005 0.0132
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.004 0.0096 0.0263
Echinococcus granulosus peregrin 0.0029 0.0054 0.0098
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0355 0.0352
Loa Loa (eye worm) hypothetical protein 0.048 0.1782 0.5004
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Schistosoma mansoni subfamily M14A unassigned peptidase (M14 family) 0.0068 0.0205 0.0388
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0192 0.0677 0.1971
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0055 0.0156 0.0431
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0055 0.0156 0.0295
Echinococcus granulosus g protein coupled receptor 0.0055 0.0156 0.0295
Loa Loa (eye worm) hypothetical protein 0.0034 0.0076 0.0203
Echinococcus multilocularis neuropeptide receptor A26 0.0055 0.0156 0.0295
Trypanosoma brucei oxidoreductase-like protein 0.0019 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Schistosoma mansoni myosin xvIII 0.0055 0.0156 0.0295
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0026 0.0045 0.008
Loa Loa (eye worm) hypothetical protein 0.0026 0.0045 0.0117
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.009 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0085 0.0226
Onchocerca volvulus 0.0019 0.0017 0.0038
Mycobacterium leprae Possible regulatory protein 0.0025 0.0041 0.0107
Echinococcus multilocularis retinol dehydrogenase 11 0.0019 0.0017 0.0027
Echinococcus multilocularis g protein coupled receptor 0.0055 0.0156 0.0295
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0046 0.0082
Leishmania major hypothetical protein, conserved 0.0035 0.0078 0.0075
Brugia malayi beta-lactamase family protein 0.0035 0.0078 0.0211
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0013
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.004
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.004 0.0096 0.0341
Echinococcus multilocularis steroid dehydrogenase 0.0019 0.0017 0.0027
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0019 0.0017 0.004
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.004 0.0096 0.0263
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0722 0.2707 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0192 0.0677 0.1862
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0019 0.0017 0.0014
Schistosoma mansoni cytochrome P450 0.004 0.0096 0.0178
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.004 0.0096 0.0263
Onchocerca volvulus 0.0055 0.0156 0.0422
Onchocerca volvulus 0.0055 0.0156 0.0422
Brugia malayi Carboxylesterase family protein 0.0108 0.0356 0.0993
Giardia lamblia GTOR 0.0046 0.012 0.0433
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0013
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0019 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0192 0.0677 0.1862
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0049 0.0126
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0013
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0041 0.0104
Echinococcus multilocularis G protein coupled receptor 139 0.0055 0.0156 0.0295
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.0304 0.0579
Plasmodium falciparum transporter, putative 0.0026 0.0045 0.0116
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0288 0.1047 1
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0191 0.0528
Brugia malayi Augmenter of liver regeneration 0.0035 0.0077 0.0208
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0043 0.004
Mycobacterium ulcerans short-chain type oxidoreductase 0.0019 0.0017 0.0051
Schistosoma mansoni neuropeptide F-like receptor 0.0055 0.0156 0.0295
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0055 0.0156 0.0295
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Schistosoma mansoni disulfide oxidoreductase 0.0192 0.0677 0.1298
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0048 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0084 0.0224
Echinococcus multilocularis hyperpolarization activated cyclic 0.0018 0.0013 0.002
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0008 0.0012
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0018 0.0013 0.002
Echinococcus granulosus neuropeptide FF receptor 2 0.0055 0.0156 0.0295
Leishmania major hypothetical protein, conserved 0.0192 0.0677 0.0674
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0048 0.0128 0.0241
Entamoeba histolytica hypothetical protein, conserved 0.0019 0.0017 0.0133
Mycobacterium ulcerans lipase LipD 0.0035 0.0078 0.0277
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0018 0.0013 0.0029
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0192 0.0677 0.6458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0049 0.0128
Loa Loa (eye worm) hypothetical protein 0.0035 0.0078 0.0211
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0355 0.0678
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0156 0.0295
Mycobacterium tuberculosis Conserved protein 0.0035 0.0078 0.0213
Onchocerca volvulus 0.0108 0.0356 0.0974
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0511 0.0508
Echinococcus granulosus microtubule associated protein 2 0.1374 0.5199 1
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0035 0.0077 0.0142
Mycobacterium tuberculosis Possible oxidoreductase 0.0019 0.0017 0.004
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0934 0.3515 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0078 0.0277
Trypanosoma cruzi NADH dehydrogenase, putative 0.0192 0.0677 0.0674
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0019 0.0017 0.0133
Schistosoma mansoni rab6-interacting 0.0157 0.0543 0.104
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0008 0.0009
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0355 0.0991
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0192 0.0677 0.1971
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0136 0.0375
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0048 0.0128 0.0352
Echinococcus granulosus intermediate filament protein 0.0055 0.0154 0.0291
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.0958 0.2636
Echinococcus multilocularis inositol monophosphatase 1 0.0148 0.0511 0.0977
Echinococcus multilocularis g protein coupled receptor 0.0055 0.0156 0.0295
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0609 0.1673
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0017 0.0051
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0078 0.0144
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0055 0.0156 0.0431
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.003 0.0058 0.0105
Toxoplasma gondii selenide, water dikinase 0.0192 0.0677 0.1971
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Onchocerca volvulus 0.0017 0.0008 0.0012
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0152 0.0527 0.1008
Leishmania major hypothetical protein, conserved 0.0026 0.0043 0.004
Giardia lamblia Short-chain dehydrogenase, putative 0.0019 0.0017 0.0051
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.012 0.0226
Brugia malayi Cathepsin L-like precursor 0.0017 0.0008 0.0013
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0055 0.0496
Schistosoma mansoni neprilysin 0.003 0.0058 0.0105
Echinococcus multilocularis fmrfamide receptor 0.0055 0.0156 0.0295
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0101 0.0332 0.0329
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0019 0.0017 0.0014
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0531 0.1974 0.5544
Giardia lamblia Thioredoxin reductase 0.0192 0.0677 0.2493
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.004 0.0096 0.0341
Leishmania major dehydrogenase-like protein 0.0019 0.0017 0.0014
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0005 0.0003
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0005 0.0003
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0174 0.0328
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0058 0.0164 0.031
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0017 0.0133
Onchocerca volvulus 0.0019 0.0017 0.0038
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0017 0.0014
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0196 0.0693 0.069
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0055 0.0156 0.0431
Loa Loa (eye worm) hypothetical protein 0.0037 0.0085 0.0231
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0019 0.0017 0.004
Loa Loa (eye worm) hepatopoietin HPO2 0.0035 0.0077 0.0208
Echinococcus multilocularis somatostatin receptor 0.0055 0.0156 0.0295
Mycobacterium ulcerans hypothetical protein 0.0035 0.0078 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0092 0.0245
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.004 0.0096 0.0263
Trichomonas vaginalis glutathione reductase, putative 0.0722 0.2707 0.7466
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0017 0.0014
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0019 0.0017 0.004
Loa Loa (eye worm) cytochrome P450 family protein 0.0057 0.0162 0.0448
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.004 0.0096 0.0341
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.0156 0.0295
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Loa Loa (eye worm) peptidase family M13 containing protein 0.0084 0.0266 0.074
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0097 0.0181
Treponema pallidum fructose-bisphosphate aldolase 0.0288 0.1047 0.3741
Brugia malayi neuropeptide F receptor 0.0055 0.0156 0.0431
Loa Loa (eye worm) hypothetical protein 0.0108 0.0356 0.0993
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0355 0.3372
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0045 0.0121
Loa Loa (eye worm) hypothetical protein 0.0114 0.038 0.1061
Onchocerca volvulus 0.0019 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0108 0.0356 0.0993
Schistosoma mansoni inositol monophosphatase 0.0148 0.0511 0.0977
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.004 0.0096 0.0263
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0055 0.0156 0.0295
Schistosoma mansoni hypothetical protein 0.003 0.0058 0.0105
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0332 0.0908
Onchocerca volvulus 0.0035 0.0078 0.0206
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0041 0.0104
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0179 0.063 0.1206
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0021
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.004 0.0096 0.0263
Onchocerca volvulus 0.0019 0.0017 0.0038
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0043 0.0126
Loa Loa (eye worm) melatonin receptor type 1A 0.0055 0.0156 0.0431
Echinococcus granulosus sodium and chloride dependent glycine 0.0026 0.0045 0.008
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.004
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0192 0.0677 0.1862
Echinococcus multilocularis cysteine protease 0.0017 0.0008 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.221 0.8396 0.8395
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0108 0.0356 0.0993
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0355 0.1002
Leishmania major cathepsin L-like protease 0.0064 0.0187 0.0184
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.0013 0.002
Plasmodium vivax steroid dehydrogenase, putative 0.0019 0.0017 0.0051
Brugia malayi hypothetical protein 0.0152 0.0527 0.1474
Echinococcus granulosus lipoxygenase domain containing protein 0.0157 0.0543 0.104
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0108 0.0356 0.0679
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0638 0.2383 0.458
Trypanosoma brucei hypothetical protein, conserved 0.0192 0.0677 0.0674
Echinococcus granulosus JmjC domain containing protein 4 0.0025 0.0039 0.0069
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Echinococcus granulosus survival motor neuron protein 1 0.0471 0.1745 0.3352
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0005 0.0003
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0055 0.0156 0.0295
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0156 0.0295
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0078 0.0211
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0018 0.0013 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0092 0.0245
Echinococcus granulosus biogenic amine 5HT receptor 0.0055 0.0156 0.0295
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0005 0.0003
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0005 0.0003
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.012 0.033
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0085 0.0082
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Loa Loa (eye worm) jmjC domain-containing protein 0.0093 0.03 0.0834
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0033 0.007 0.0067
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0609 0.1673
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0192 0.0677 0.2493
Brugia malayi dehydrogenases, short chain protein 2 0.0019 0.0017 0.004
Brugia malayi glutathione reductase 0.091 0.3424 0.9624
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0055 0.0143
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.0048 0.0087
Echinococcus granulosus Ankyrin 0.003 0.0057 0.0104
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.0304 0.0579
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0101 0.0332 0.0329
Plasmodium vivax SET domain protein, putative 0.0121 0.0408 0.1191
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0003
Echinococcus multilocularis neuropeptide receptor 0.0055 0.0156 0.0295
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0085 0.0081
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0013 0.002
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0019 0.0017 0.004
Onchocerca volvulus Netrin receptor homolog 0.0029 0.0056 0.0146
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.0077 0.0211
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0055 0.0156 0.0295
Schistosoma mansoni netrin receptor unc5 0.0029 0.0056 0.0102
Brugia malayi Inositol-1 0.0148 0.0511 0.1428
Loa Loa (eye worm) hypothetical protein 0.0108 0.0356 0.0993
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0041 0.0073
Mycobacterium ulcerans carveol-like dehydrogenase 0.0019 0.0017 0.0051
Onchocerca volvulus 0.0055 0.0156 0.0422
Brugia malayi hypothetical protein 0.0026 0.0045 0.0117
Onchocerca volvulus 0.0199 0.0705 0.1937
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0025 0.0041 0.0139
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0192 0.0677 0.0674
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.004
Schistosoma mansoni neuroligin 3 (S09 family) 0.0108 0.0356 0.0679
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.01
Echinococcus multilocularis thioredoxin glutathione reductase 0.091 0.3424 0.6582
Brugia malayi Carboxylesterase family protein 0.0108 0.0356 0.0993
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0028 0.005 0.0091
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0018 0.0013 0.002
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.0483 0.1365
Echinococcus multilocularis dro:myosuppressin receptor 0.0055 0.0156 0.0295
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0043 0.0111
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0045 0.008
Plasmodium falciparum LCCL domain-containing protein 0.0157 0.0543 0.1575
Treponema pallidum oxidoreductase 0.0192 0.0677 0.2347
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0084 0.0155
Schistosoma mansoni ap endonuclease 0.0038 0.009 0.0166
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0192 0.0677 0.6458
Trichomonas vaginalis spcc417.12 protein, putative 0.0108 0.0356 0.0975
Loa Loa (eye worm) acetylcholinesterase 1 0.0638 0.2383 0.6696
Plasmodium vivax multidomain scavenger receptor, putative 0.0157 0.0543 0.1587
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Brugia malayi beta-lactamase family protein 0.0035 0.0078 0.0211
Schistosoma mansoni glutamate synthase 0.0192 0.0677 0.1298
Echinococcus multilocularis steroid dehydrogenase 0.0019 0.0017 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0017 0.0014
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0045 0.0131
Schistosoma mansoni sulfide quinone reductase 0.0192 0.0677 0.1298
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0085 0.0231
Echinococcus granulosus bloom syndrome protein 0.0022 0.0027 0.0045
Brugia malayi RE15519p 0.0055 0.0156 0.0431
Schistosoma mansoni hypothetical protein 0.0029 0.0054 0.0098
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0019 0.0017 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0121 0.0408 0.0779
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0192 0.0677 0.1971
Echinococcus multilocularis neuropeptides capa receptor 0.0055 0.0156 0.0295
Leishmania major hypothetical protein, conserved 0.0019 0.0017 0.0014
Schistosoma mansoni jumonji/arid domain-containing protein 0.0093 0.03 0.0571
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0905 0.3407 0.655
Giardia lamblia Fructose-bisphosphate aldolase 0.0288 0.1047 0.386
Onchocerca volvulus 0.0019 0.0017 0.0038
Echinococcus granulosus hypothetical protein 0.0019 0.0017 0.0027
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0045 0.008
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0085 0.0158
Giardia lamblia NADH oxidase lateral transfer candidate 0.0722 0.2707 1
Onchocerca volvulus 0.0157 0.0543 0.1491
Echinococcus granulosus somatostatin receptor 0.0055 0.0156 0.0295
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0143
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0026 0.0045 0.008
Loa Loa (eye worm) hypothetical protein 0.0114 0.038 0.1061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.012 0.0324
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0055 0.0156 0.0431
Leishmania major hypothetical protein, conserved 0.0019 0.0017 0.0014
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0078 0.0207
Mycobacterium tuberculosis Conserved protein 0.0035 0.0078 0.0213
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.0958 0.2636
Onchocerca volvulus 0.0055 0.0156 0.0422
Brugia malayi Cyclic-nucleotide gated cation channel 0.0018 0.0013 0.0029
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0027 0.0045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0304 0.0579
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0192 0.0677 0.192
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1929 0.7322 0.7321
Chlamydia trachomatis thioredoxin reductase 0.0192 0.0677 0.2493
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0117 0.0391 0.0746
Entamoeba histolytica hypothetical protein 0.0036 0.0084 0.0767
Echinococcus granulosus retinol dehydrogenase 11 0.0019 0.0017 0.0027
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0722 0.2707 0.7905
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1047 0.2883
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0055 0.0156 0.0295
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0187 0.0184
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0027
Onchocerca volvulus 0.0026 0.0045 0.0114
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0059 0.0153
Mycobacterium tuberculosis Probable dehydrogenase 0.0403 0.1485 0.422
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0017 0.0133
Brugia malayi hypothetical protein 0.0036 0.0084 0.0226
Echinococcus granulosus dro:myosuppressin receptor 0.0055 0.0156 0.0295
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0192 0.0677 0.0674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0075 0.0199
Echinococcus granulosus lamin dm0 0.0055 0.0154 0.0291
Loa Loa (eye worm) hypothetical protein 0.0155 0.0537 0.1503
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0187 0.0184
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1047 0.2883
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0055 0.0156 0.0295
Treponema pallidum thioredoxin reductase (trxB) 0.0192 0.0677 0.2347
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0039
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.0045 0.008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0119
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0192 0.0677 0.192
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.012 0.0117
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.004 0.0096 0.0263
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0026 0.0045 0.008
Schistosoma mansoni phosphatidylserine receptor 0.0025 0.0039 0.0069
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0378 0.139 0.3901
Brugia malayi Carboxylesterase family protein 0.0108 0.0356 0.0993
Echinococcus multilocularis lamin dm0 0.0055 0.0154 0.0291
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0019 0.0017 0.0051
Trichomonas vaginalis glutamate synthase, putative 0.0192 0.0677 0.1862
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0017 0.0014
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0191 0.0188
Schistosoma mansoni BC026374 protein (S09 family) 0.0108 0.0356 0.0679
Brugia malayi G protein-coupled receptor 0.0055 0.0156 0.0431
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0027 0.0066
Toxoplasma gondii thioredoxin reductase 0.091 0.3424 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0157 0.0543 0.104
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0192 0.0677 0.1897
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0045 0.0121
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0019 0.0017 0.0039
Onchocerca volvulus 0.0068 0.0205 0.0556
Schistosoma mansoni neprilysin-2 (M13 family) 0.0058 0.0164 0.031
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0934 0.3515 1
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0609 0.1673
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0101 0.0332 0.0961
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0013 0.0028
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0039
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0108 0.0356 0.0679
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0019 0.0017 0.004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0722 0.2707 0.2705
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0055 0.0156 0.0295
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0424 0.0809
Trichomonas vaginalis inositol monophosphatase, putative 0.0016 0.0003 0.0001
Leishmania major cathepsin L-like protease 0.0064 0.0187 0.0184
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0055 0.0143
Echinococcus multilocularis lamin 0.0055 0.0154 0.0291
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0722 0.2707 1
Schistosoma mansoni protein phosphatase 2C 0.0025 0.0039 0.0069
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0722 0.2707 0.5203
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0148 0.0511 0.1483
Brugia malayi GnHR receptor homolog 0.0055 0.0156 0.0431
Echinococcus granulosus peptide allatostatin:somatostatin 0.0055 0.0156 0.0295
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0085 0.0158
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0424 0.0809
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0041 0.0073
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0057 0.0151
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Mycobacterium leprae Probable lipase LipE 0.0035 0.0078 0.0213
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0017 0.0027
Echinococcus granulosus RUN 0.0157 0.0543 0.104
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.012 0.0117
Brugia malayi Peptidase family M13 containing protein 0.0114 0.038 0.1061
Mycobacterium leprae Probable oxidoreductase 0.0019 0.0017 0.004
Onchocerca volvulus 0.0055 0.0156 0.0422
Brugia malayi phosphofructokinase 0.0108 0.0355 0.0991
Brugia malayi hypothetical protein 0.0026 0.0043 0.0112
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.009 0.0238
Leishmania major protein kinase, putative 0.0026 0.0044 0.0041
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0017 0.0014
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0511 0.0508
Entamoeba histolytica hypothetical protein, conserved 0.0019 0.0017 0.0133
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0054 0.0148
Leishmania major hypothetical protein, conserved 0.0019 0.0017 0.0014
Trichomonas vaginalis set domain proteins, putative 0.0962 0.3625 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0136 0.0375
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.01
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0154 0.0426
Echinococcus multilocularis oxidoreductase 0.0019 0.0017 0.0027
Echinococcus granulosus nuclear factor of activated T cells 5 0.015 0.0519 0.0992
Schistosoma mansoni survival motor neuron protein 0.0096 0.0311 0.0593
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0019 0.0017 0.0039
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0017 0.0051
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0078 0.0207
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0049 0.0128
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0101 0.0332 0.0329
Leishmania major ferric reductase, putative 0.0033 0.007 0.0067
Loa Loa (eye worm) neuropeptide F receptor 0.0055 0.0156 0.0431
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0078 0.0144
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0017 0.0014
Schistosoma mansoni amine GPCR 0.0055 0.0156 0.0295
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0103 0.0276
Onchocerca volvulus 0.0108 0.0356 0.0974
Leishmania major cytochrome p450-like protein 0.004 0.0096 0.0092
Brugia malayi Tachykinin-like peptides receptor 99D 0.0055 0.0156 0.0431
Schistosoma mansoni glutamate synthase 0.0192 0.0677 0.1298
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0192 0.0677 0.1862
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0055 0.0156 0.0295
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.004 0.0096 0.0263
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.0304 0.0579
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0084 0.0266 0.074
Echinococcus granulosus hypothetical protein 0.0764 0.2865 0.5508
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0013
Echinococcus granulosus serotonin transporter 0.0155 0.0537 0.1028
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0025 0.0039 0.0036
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0019 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0086 0.0274 0.0762
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0075 0.021
Trypanosoma cruzi cytochrome P450, putative 0.0057 0.0162 0.0159
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.009 0.0166
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0078 0.0213
Echinococcus multilocularis retinol dehydrogenase 11 0.0019 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Echinococcus granulosus chromobox protein 1 0.0069 0.0208 0.0393
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.004
Schistosoma mansoni hypothetical protein 0.0029 0.0056 0.0102
Plasmodium vivax glutathione reductase, putative 0.091 0.3424 1
Loa Loa (eye worm) hypothetical protein 0.0471 0.1745 0.4901
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.003 0.0057 0.0104
Schistosoma mansoni neuropeptide receptor 0.0055 0.0156 0.0295
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0013
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0041
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0018 0.0013 0.002
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0027 0.0045
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Mycobacterium tuberculosis Probable oxidoreductase 0.0934 0.3515 1
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0355 0.0972
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.012 0.0226
Toxoplasma gondii exonuclease III APE 0.0038 0.009 0.0252
Onchocerca volvulus Neuropeptide F receptor homolog 0.0055 0.0156 0.0422
Echinococcus multilocularis JmjC domain containing protein 4 0.0025 0.0039 0.0069
Plasmodium vivax JmjC domain containing protein 0.0025 0.0039 0.0114
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.0304 0.0847
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0135 0.0132
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0008 0.0009
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0033 0.007 0.0067
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0187 0.0184
Loa Loa (eye worm) follicle stimulating hormone receptor 0.032 0.1168 0.3278
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.012 0.0324
Echinococcus granulosus GPCR family 2 0.0016 0.0005 0.0003
Brugia malayi Cathepsin L-like precursor 0.0017 0.0008 0.0013
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0085 0.0081
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0192 0.0677 0.1862
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0017 0.0027
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0722 0.2707 1
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0055 0.0191
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0192 0.0677 0.1897
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0187 0.0184
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0019 0.0017 0.0014
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0019 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0086 0.0274 0.0762
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0041
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0017 0.0027
Brugia malayi putative neuropeptide receptor 0.0055 0.0156 0.0431
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0005 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Brugia malayi Cathepsin L-like precursor 0.0017 0.0008 0.0013
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0017 0.0133
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0108 0.0356 0.0679
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0078 0.0213
Loa Loa (eye worm) hypothetical protein 0.003 0.006 0.0159
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0179 0.063 0.1206
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0041 0.0038
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0722 0.2707 0.7904
Echinococcus granulosus hypothetical protein 0.0019 0.0017 0.0027
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0355 0.0991
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0019 0.0017 0.0014
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0192 0.0677 0.0674
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0043 0.0116
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0039 0.01
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0934 0.3515 1
Brugia malayi glutamate synthase 0.0192 0.0677 0.1897
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Toxoplasma gondii peptidase family M13 protein 0.0114 0.038 0.1102
Loa Loa (eye worm) hypothetical protein 0.0638 0.2383 0.6696
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Onchocerca volvulus 0.0055 0.0156 0.0422
Schistosoma mansoni hypothetical protein 0.0036 0.0084 0.0155
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Onchocerca volvulus 0.0055 0.0156 0.0422
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Loa Loa (eye worm) inositol-1 0.0148 0.0511 0.1428
Echinococcus multilocularis tar DNA binding protein 0.0125 0.0424 0.0809
Loa Loa (eye worm) TAR-binding protein 0.0125 0.0424 0.1183
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.004 0.0096 0.0263
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0945 0.3557 1
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0019 0.0017 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0156 0.0295
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.0156 0.0295
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0019 0.0017 0.0014
Echinococcus granulosus thioredoxin glutathione reductase 0.091 0.3424 0.6582
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.004
Schistosoma mansoni glutamate synthase 0.0192 0.0677 0.1298
Brugia malayi ORL1-like opioid receptor 0.0055 0.0156 0.0431
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0048 0.0128 0.0352
Loa Loa (eye worm) hypothetical protein 0.048 0.1782 0.5004
Schistosoma mansoni adenoreceptor 0.0055 0.0156 0.0295
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0191 0.0188
Plasmodium falciparum steroid dehydrogenase, putative 0.0019 0.0017 0.0036
Trypanosoma cruzi trypanothione reductase, putative 0.091 0.3424 0.3421
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0019 0.0017 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0192 0.0677 0.192
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.009 0.0268
Echinococcus multilocularis conserved hypothetical protein 0.0019 0.0017 0.0027
Mycobacterium tuberculosis Conserved protein 0.0035 0.0078 0.0213
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.0141 0.0266
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0156 0.0295
Loa Loa (eye worm) hypothetical protein 0.0084 0.0266 0.074
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0029 0.0056 0.0102
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0174 0.063
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0039
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0055 0.0156 0.0295
Echinococcus granulosus acetylcholinesterase 0.0638 0.2383 0.458
Echinococcus multilocularis Polycystic kidney disease protein 0.0157 0.0543 0.104
Echinococcus granulosus Polycystic kidney disease protein 0.0157 0.0543 0.104
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0108
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0008 0.0009
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0013 0.002
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0017 0.0014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1047 0.2883
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0005 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0013
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0078 0.0213
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0055 0.0156 0.0295
Mycobacterium leprae Conserved hypothetical protein 0.004 0.0096 0.0263
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0196 0.0693 0.069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0013
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0027
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0688 0.2574 0.4947
Brugia malayi Retinol dehydrogenase 12 0.0019 0.0017 0.004
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0019 0.0017 0.0014
Schistosoma mansoni carbonyl reductase 0.0019 0.0017 0.0027
Schistosoma mansoni ankyrin 23/unc44 0.0029 0.0056 0.0102
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0005 0.0005
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0026 0.0045 0.008
Brugia malayi Uncoordinated protein 44 0.0029 0.0056 0.0149
Brugia malayi Bromodomain containing protein 0.0029 0.0054 0.0143
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0133 0.0451 0.0862
Echinococcus multilocularis RUN 0.0157 0.0543 0.104
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0027 0.0045
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0085 0.0158
Schistosoma mansoni aryl hydrocarbon receptor 0.0097 0.0317 0.0603
Echinococcus multilocularis geminin 0.0172 0.0601 0.115
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0041 0.0073
Mycobacterium tuberculosis Probable reductase 0.0403 0.1485 0.422
Schistosoma mansoni chromobox protein 0.0069 0.0208 0.0393
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0108 0.0356 0.0679
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0055 0.0143
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0017 0.0014
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0192 0.0677 0.1298
Schistosoma mansoni biogenic amine receptor 0.0055 0.0156 0.0295
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0055 0.0156 0.0431
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0722 0.2707 0.2705
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0108 0.0356 0.0679
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.0304 0.0579
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0018 0.0013 0.002
Echinococcus multilocularis jun protein 0.0253 0.0913 0.1751
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0055 0.0156 0.0295
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.004 0.0096 0.0341
Onchocerca volvulus 0.0055 0.0156 0.0422
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0645 0.1772
Onchocerca volvulus 0.0055 0.0156 0.0422
Brugia malayi Dopamine receptor protein 1 0.0055 0.0156 0.0431
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0019 0.0017 0.0014
Echinococcus granulosus phd:f box containing protein 0.0025 0.0039 0.0069
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0017 0.0051
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.004 0.0096 0.0341
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0722 0.2707 0.5203
Schistosoma mansoni acetylcholinesterase 0.0108 0.0356 0.0679
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.004 0.0096 0.0263
Brugia malayi hypothetical protein 0.0108 0.0356 0.0993
Loa Loa (eye worm) cysteine protease 0.0017 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Loa Loa (eye worm) hypothetical protein 0.0152 0.0527 0.1474
Toxoplasma gondii hypothetical protein 0.0026 0.0045 0.0121
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0174 0.0328
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0019 0.0017 0.0027
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0087 0.0161
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0039 0.0036
Brugia malayi PAS domain containing protein 0.0097 0.0317 0.0882
Leishmania major short chain dehydrogenase/reductase, putative 0.0019 0.0017 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0055 0.0143
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0019 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0054 0.0151 0.0415
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0005 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0035 0.0078 0.0211
Mycobacterium ulcerans beta-lactamase 0.0035 0.0078 0.0277
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0008 0.0009
Schistosoma mansoni hypothetical protein 0.0055 0.0156 0.0295
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0058 0.0164 0.031
Loa Loa (eye worm) hypothetical protein 0.0108 0.0356 0.0993
Echinococcus granulosus tachykinin peptides receptor 99D 0.0055 0.0156 0.0295
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0018 0.0013 0.002
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0043 0.004
Schistosoma mansoni hypothetical protein 0.0053 0.0147 0.0277
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0055 0.0191
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.009 0.013
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.0958 0.2636
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0019 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0026 0.0045 0.008
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0055 0.0151
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0055 0.0156 0.0295
Leishmania major C-8 sterol isomerase-like protein 0.0378 0.139 0.1387
Schistosoma mansoni polycystin 1-related 0.0157 0.0543 0.104
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0017 0.0051
Leishmania major cathepsin L-like protease 0.0017 0.0008 0.0005
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.004 0.0096 0.0341
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0003
Brugia malayi hypothetical protein 0.0055 0.0156 0.0431
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.0077 0.0074
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0192 0.0677 0.1298
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0041 0.0104
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.004
Brugia malayi Dopamine receptor protein 2 0.0055 0.0156 0.0431
Echinococcus granulosus lamin 0.0055 0.0154 0.0291
Trypanosoma cruzi trypanothione reductase, putative 0.0722 0.2707 0.2705
Schistosoma mansoni sodium/chloride dependent transporter 0.0026 0.0045 0.008
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.0958 0.2636
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.0045 0.008
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0192 0.0677 0.2493
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0187 0.0184
Brugia malayi intermediate filament protein 0.0055 0.0154 0.0426
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0017 0.0014
Onchocerca volvulus 0.0017 0.0008 0.0012
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0019 0.0017 0.0041
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Schistosoma mansoni neuropeptide receptor 0.0055 0.0156 0.0295
Echinococcus granulosus para nitrobenzyl esterase 0.0108 0.0356 0.0679
Entamoeba histolytica hypothetical protein 0.0019 0.0017 0.0133
Schistosoma mansoni hypothetical protein 0.003 0.0058 0.0105
Brugia malayi sulfakinin receptor protein 0.0055 0.0156 0.0431
Onchocerca volvulus 0.0068 0.0205 0.0556
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0048 0.0128 0.0241
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0054 0.0143
Entamoeba histolytica cysteine protease, putative 0.0017 0.0008 0.0043
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0722 0.2707 0.7608
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Brugia malayi jmjC domain containing protein 0.0025 0.0039 0.01
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.004
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0008 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0013
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0085 0.0158
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0019 0.0017 0.004
Schistosoma mansoni chromobox protein 0.0069 0.0208 0.0393
Echinococcus granulosus serotonin receptor 0.0055 0.0156 0.0295
Brugia malayi hypothetical protein 0.0471 0.1745 0.4901
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0156 0.0295
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0085 0.0082
Echinococcus multilocularis fmrfamide receptor 0.0055 0.0156 0.0295
Giardia lamblia Hypothetical protein 0.0019 0.0017 0.0051
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1929 0.7322 0.7321
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0013
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0101 0.0332 0.0329
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0019 0.0017 0.0038
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0196 0.0693 0.069
Echinococcus granulosus inositol monophosphatase 1 0.0148 0.0511 0.0977
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0017 0.0014
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0403 0.1485 0.422
Loa Loa (eye worm) blistered cuticle protein 3 0.007 0.0213 0.0589
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Loa Loa (eye worm) hypothetical protein 0.0155 0.0537 0.1503
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0041 0.0104
Brugia malayi Cathepsin L-like precursor 0.0017 0.0008 0.0013
Schistosoma mansoni biogenic amine receptor 0.0055 0.0156 0.0295
Brugia malayi Serotonin receptor 0.0528 0.1962 0.5512
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0055 0.0156 0.0295
Brugia malayi Carboxylesterase family protein 0.0108 0.0356 0.0993
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0019 0.0017 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0013
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0722 0.2707 0.2705
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.009 0.0318
Loa Loa (eye worm) thioredoxin reductase 0.091 0.3424 0.9624
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0025 0.0039 0.0069
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.004
Onchocerca volvulus 0.0017 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0193 0.0683 0.1912
Echinococcus multilocularis subfamily M14A unassigned peptidase 0.0068 0.0205 0.0388
Schistosoma mansoni opsin-like receptor 0.0055 0.0156 0.0295
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0192 0.0677 0.1862
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0013
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0166 0.0163
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Leishmania major cathepsin L-like protease 0.0017 0.0008 0.0005
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0017 0.0014
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0078 0.0213
Brugia malayi hypothetical protein 0.0199 0.0705 0.1975
Brugia malayi Pre-SET motif family protein 0.0846 0.3178 0.8933
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.004 0.0096 0.0341
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0192 0.0677 0.1298
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0192 0.0677 0.192
Echinococcus granulosus tm gpcr rhodopsin 0.0905 0.3407 0.655
Echinococcus granulosus 7TM GPCR rhodopsin 0.0055 0.0156 0.0295
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0192 0.0677 0.1298
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.0801 0.2272
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0722 0.2707 0.5203
Echinococcus granulosus geminin 0.0172 0.0601 0.115
Brugia malayi follicle stimulating hormone receptor 0.032 0.1168 0.3278
Trypanosoma cruzi short chain dehydrogenase, putative 0.0019 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0026 0.0045 0.0117
Echinococcus multilocularis g-protein coupled receptor 0.0055 0.0156 0.0295
Trypanosoma brucei trypanothione reductase 0.091 0.3424 0.3421
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0019 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0043 0.0109 0.0299
Loa Loa (eye worm) hypothetical protein 0.0039 0.0092 0.0249
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0332 0.0633
Brugia malayi hypothetical protein 0.0327 0.1194 0.3352
Loa Loa (eye worm) neuropeptide F receptor 0.0055 0.0156 0.0431
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0208 0.0565
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0148 0.0511 0.1402
Schistosoma mansoni alpha-1 adrenergic receptor 0.0055 0.0156 0.0295
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.0483 0.1773
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Onchocerca volvulus 0.0055 0.0156 0.0422
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.0077 0.0074
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0017 0.0014
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0192 0.0677 0.1298
Brugia malayi Doublecortin family protein 0.0157 0.0543 0.152
Onchocerca volvulus 0.0025 0.0041 0.0103
Onchocerca volvulus 0.0035 0.0078 0.0206
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0084 0.0224
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0121 0.0408 0.0779
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0019 0.0017 0.0014
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.0077 0.0225
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0196 0.0693 0.1964
Onchocerca volvulus 0.0055 0.0156 0.0422
Echinococcus granulosus chromobox protein 1 0.0069 0.0208 0.0393
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0055 0.0156 0.0295
Echinococcus granulosus acetylcholinesterase 0.0638 0.2383 0.458
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0187 0.0184
Loa Loa (eye worm) hypothetical protein 0.0025 0.0039 0.01
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0722 0.2707 0.7904
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0114 0.038 0.1061
Plasmodium vivax amine transporter, putative 0.0026 0.0045 0.0131
Loa Loa (eye worm) hypothetical protein 0.0035 0.0078 0.0211
Echinococcus multilocularis neuropeptide receptor 0.0055 0.0156 0.0295
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0013 0.002
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.004 0.0096 0.0341
Echinococcus multilocularis neuropeptide FF receptor 2 0.0055 0.0156 0.0295
Loa Loa (eye worm) zinc metallopeptidase 4 0.0028 0.005 0.0132
Schistosoma mansoni gliotactin 0.0108 0.0356 0.0679
Brugia malayi hypothetical protein 0.012 0.0405 0.1129
Loa Loa (eye worm) hypothetical protein 0.0246 0.0887 0.2486
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0018 0.0013 0.002
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0196 0.0693 0.069
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0041 0.0104
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0191 0.0188
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0016 0.0003 0.0001
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0005 0.0002
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0846 0.3178 0.8933
Loa Loa (eye worm) hypothetical protein 0.0035 0.0078 0.0211
Schistosoma mansoni neuropeptide F-like receptor 0.0055 0.0156 0.0295
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0028 0.005 0.0091
Schistosoma mansoni microtubule-associated protein tau 0.1374 0.5199 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.009 0.0825
Schistosoma mansoni lipoxygenase 0.0406 0.1495 0.2871
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0029 0.0056 0.0102
Onchocerca volvulus 0.0192 0.0677 0.1861
Echinococcus multilocularis sodium and chloride dependent glycine 0.0026 0.0045 0.008
Echinococcus granulosus mitogen activated protein kinase 0.0101 0.0332 0.0633
Brugia malayi jmjC domain containing protein 0.0152 0.0527 0.1474
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0017 0.0027
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0005 0.0004
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0355 0.0678
Giardia lamblia PHD finger protein 15 0.0029 0.0054 0.0187
Brugia malayi hypothetical protein 0.0157 0.0543 0.152
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.004 0.0096 0.0341
Leishmania major cathepsin L-like protease 0.0017 0.0008 0.0005
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0078 0.0144
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.0099
Loa Loa (eye worm) dehydrogenase 0.0019 0.0017 0.004
Echinococcus granulosus lysine specific demethylase 5A 0.0093 0.03 0.0571
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0044 0.0041
Plasmodium falciparum amino acid transporter, putative 0.0026 0.0045 0.0116
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0013
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0017 0.0051
Schistosoma mansoni biogenic amine (5HT) receptor 0.0055 0.0156 0.0295
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0403 0.1485 0.422
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0075 0.0199
Loa Loa (eye worm) hypothetical protein 0.0029 0.0056 0.0149
Schistosoma mansoni hypothetical protein 0.0192 0.0677 0.1298
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0019 0.0017 0.004
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1929 0.7322 0.7321
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0019 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0035 0.0078 0.0211
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0085 0.0302
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0025 0.0039 0.0104
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0041 0.0104
Echinococcus multilocularis G-protein coupled receptor, putative 0.0055 0.0156 0.0295
Echinococcus multilocularis sodium and chloride dependent glycine 0.0026 0.0045 0.008
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.012 0.0117
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0044 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0048 0.0125
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.004
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0019 0.0017 0.004
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0008 0.0009
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0078 0.0228
Brugia malayi oxidoreductase 0.0019 0.0017 0.004
Schistosoma mansoni loxhd1 0.0157 0.0543 0.104
Plasmodium vivax thioredoxin reductase, putative 0.091 0.3424 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0168 0.0463
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.004 0.0096 0.0263
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0008 0.0009
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0019 0.0017 0.0027
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0332 0.0908
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0196 0.0693 0.2551
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0009 0.0012
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.012 0.1121
Echinococcus granulosus hyperpolarization activated cyclic 0.0018 0.0013 0.002
Echinococcus multilocularis microtubule associated protein 2 0.1374 0.5199 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0511 0.0508
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.009 0.0245
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0045 0.0117
Loa Loa (eye worm) CYP4Cod1 0.0057 0.0162 0.0448
Echinococcus granulosus sodium channel protein 0.0121 0.0408 0.0779
Giardia lamblia Kinase, CMGC MAPK 0.0101 0.0332 0.1216
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.004
Schistosoma mansoni hypothetical protein 0.0096 0.0311 0.0593
Echinococcus granulosus mitogen activated protein kinase 3 0.0101 0.0332 0.0633
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0078 0.0213
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0355 0.0972
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0019 0.0017 0.0014
Entamoeba histolytica thioredoxin reductase, putative 0.0192 0.0677 0.6458
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0609 0.1673
Echinococcus granulosus WW domain containing oxidoreductase 0.0019 0.0017 0.0027
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0055 0.0156 0.0295
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0645 0.1772
Echinococcus granulosus jun protein 0.0253 0.0913 0.1751
Trypanosoma cruzi cytochrome P450, putative 0.0057 0.0162 0.0159
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0355 0.3372
Loa Loa (eye worm) RNA binding protein 0.0125 0.0424 0.1183
Toxoplasma gondii cytochrome p450 superfamily protein 0.004 0.0096 0.027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0304 0.0579
Schistosoma mansoni hypothetical protein 0.003 0.0058 0.0105
Leishmania major cathepsin L-like protease 0.0064 0.0187 0.0184
Schistosoma mansoni amine GPCR 0.0055 0.0156 0.0295
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0027 0.0045
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0019 0.0017 0.0014
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.012 0.033
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Echinococcus multilocularis Ankyrin 0.003 0.0057 0.0104
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0026 0.0045 0.0117
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0078 0.0075
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0253 0.0913 0.1751
Echinococcus granulosus netrin receptor unc 5 0.0029 0.0056 0.0102
Echinococcus granulosus endothelin converting enzyme 1 0.0114 0.038 0.0725
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.221 0.8396 0.8395
Trypanosoma cruzi short chain dehydrogenase, putative 0.0019 0.0017 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0609 0.1673
Echinococcus multilocularis phd:f box containing protein 0.0025 0.0039 0.0069
Trypanosoma brucei NADH dehydrogenase 0.0192 0.0677 0.0674
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0008 0.0013
Loa Loa (eye worm) oxidoreductase 0.0019 0.0017 0.004
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0055 0.0147
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.0156 0.0295
Trypanosoma cruzi cytochrome p450-like protein, putative 0.004 0.0096 0.0092
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Echinococcus granulosus 7tm_1 domain containing protein 0.0055 0.0156 0.0295
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0187 0.0184
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0041 0.0104
Echinococcus multilocularis lysine specific demethylase 6a 0.0025 0.0039 0.0069
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0013
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0005 0.0005
Brugia malayi Dehydrogenases, short chain protein 2 0.0019 0.0017 0.004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0017 0.0027
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.009 0.0086
Echinococcus granulosus jumonji domain containing 1A 0.0025 0.0039 0.0069
Trichomonas vaginalis mercuric reductase, putative 0.0722 0.2707 0.7466
Mycobacterium ulcerans NADH dehydrogenase 0.0192 0.0677 0.2493
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0154 0.0426
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.004
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0101 0.0332 0.0329
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0019 0.0017 0.004
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0192 0.0677 0.1862
Loa Loa (eye worm) hypothetical protein 0.0086 0.0274 0.0762
Toxoplasma gondii NADPH-glutathione reductase 0.0722 0.2707 0.7905
Brugia malayi Angiotensin-converting enzyme family protein 0.0945 0.3557 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0722 0.2707 0.77
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0055 0.0156 0.0431
Trypanosoma cruzi NADH dehydrogenase, putative 0.0192 0.0677 0.0674
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0054 0.0098
Mycobacterium ulcerans dehydrogenase 0.0019 0.0017 0.0051
Echinococcus granulosus neuroligin 0.0108 0.0356 0.0679
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0043 0.0111
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0055 0.0156 0.0295
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0121 0.0408 0.0779
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0078 0.0075
Loa Loa (eye worm) hypothetical protein 0.0025 0.0041 0.0106
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0609 0.1673
Onchocerca volvulus 0.0068 0.0205 0.0556
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0041 0.0104
Schistosoma mansoni opsin-like receptor 0.0055 0.0156 0.0295
Schistosoma mansoni hypothetical protein 0.0157 0.0543 0.104
Schistosoma mansoni lamin 0.0055 0.0154 0.0291
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0085 0.0082
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0017 0.0039
Leishmania major NADH dehydrogenase, putative 0.0192 0.0677 0.0674
Schistosoma mansoni endothelin-converting enzyme-related 0.0028 0.005 0.0091
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0019 0.0017 0.004
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0017 0.0014
Mycobacterium ulcerans dehydrogenase/reductase 0.0019 0.0017 0.0051
Leishmania major cathepsin L-like protease 0.0017 0.0008 0.0005
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0041 0.0038
Echinococcus granulosus g-protein coupled receptor 0.0055 0.0156 0.0295
Echinococcus multilocularis acetylcholinesterase 0.0638 0.2383 0.458
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0179 0.063 0.0627
Loa Loa (eye worm) hypothetical protein 0.0056 0.016 0.0442
Brugia malayi cytochrome P450 0.004 0.0096 0.026
Brugia malayi Cytochrome P450 family protein 0.0057 0.0162 0.0448
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0041
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Plasmodium falciparum ferrodoxin reductase-like protein 0.0192 0.0677 0.1967
Loa Loa (eye worm) hypothetical protein 0.0084 0.0266 0.074
Mycobacterium ulcerans carboxylesterase, LipT 0.0108 0.0356 0.1305
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0078 0.0206
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0101 0.0332 0.0329
Echinococcus granulosus tar DNA binding protein 0.0125 0.0424 0.0809
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0192 0.0677 0.1298
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.009 0.0247
Entamoeba histolytica disulphide oxidoreductase, putative 0.0192 0.0677 0.6458
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0192 0.0677 0.2454
Brugia malayi Carboxylesterase family protein 0.0638 0.2383 0.6696
Brugia malayi PHD-finger family protein 0.0029 0.0054 0.0143
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0187 0.0184
Echinococcus multilocularis mitogen activated protein kinase 0.0101 0.0332 0.0633
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.221 0.8396 0.8395
Brugia malayi isocitrate dehydrogenase 0.0016 0.0005 0.0005
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0055 0.0147
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0003
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.004 0.0096 0.0341
Brugia malayi Cytochrome P450 family protein 0.0058 0.0168 0.0463
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0055 0.0143
Onchocerca volvulus 0.0055 0.0156 0.0422
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0332 0.0908
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0005 0.0005
Echinococcus multilocularis glutamate synthase 0.0192 0.0677 0.1298
Leishmania major protein kinase, putative 0.0031 0.0063 0.006
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.012 0.0226
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0026 0.0045 0.008
Echinococcus multilocularis endothelin converting enzyme 1 0.0114 0.038 0.0725
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.004
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0192 0.0677 0.0674
Schistosoma mansoni hypothetical protein 0.003 0.0058 0.0105
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0017 0.004
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.0483 0.1365
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0121 0.0408 0.0779
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0133 0.0451 0.1276
Echinococcus multilocularis neuropeptide Y receptor 0.0055 0.0156 0.0295
Brugia malayi hypothetical protein 0.0019 0.0017 0.004
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0017 0.0051
Schistosoma mansoni jumonji/arid domain-containing protein 0.0093 0.03 0.0571
Leishmania major hypothetical protein, conserved 0.0035 0.0077 0.0074
Loa Loa (eye worm) carboxylesterase 0.0108 0.0356 0.0993
Trypanosoma brucei cytochrome P450, putative 0.0057 0.0162 0.0159
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Trichomonas vaginalis steroid dehydrogenase, putative 0.0019 0.0017 0.0039
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0041
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.009 0.0166
Trypanosoma cruzi hypothetical protein, conserved 0.0192 0.0677 0.0674
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.0013 0.002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0055 0.0156 0.0295
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0103 0.0276
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.004
Schistosoma mansoni hypothetical protein 0.0055 0.0156 0.0295
Mycobacterium ulcerans ferredoxin reductase 0.0192 0.0677 0.2493
Echinococcus granulosus g protein coupled receptor 0.0055 0.0156 0.0295
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.0077 0.0074
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0192 0.0677 0.1298
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0191 0.0188
Brugia malayi G protein-coupled receptor F59B2.13 0.0055 0.0156 0.0431
Loa Loa (eye worm) hypothetical protein 0.0086 0.0274 0.0762
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0609 0.1673
Brugia malayi hypothetical protein 0.0055 0.0156 0.0431
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0019 0.0017 0.0014
Trypanosoma brucei C-8 sterol isomerase, putative 0.0378 0.139 0.1387
Entamoeba histolytica short chain dehydrogenase family protein 0.0019 0.0017 0.0133
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.0156 0.0295
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.009 0.0318
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2629 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0075 0.0199
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.004
Echinococcus granulosus alpha 1A adrenergic receptor 0.0055 0.0156 0.0295
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Brugia malayi bHLH-PAS transcription factor 0.0072 0.022 0.061
Loa Loa (eye worm) norepinephrine transporter 0.0155 0.0537 0.1503
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0055 0.0156 0.0295
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0192 0.0677 0.1967
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0192 0.0677 0.1971
Treponema pallidum sodium- and chloride- dependent transporter 0.0155 0.0537 0.1818
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.0156 0.0295
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0005 0.0003
Echinococcus multilocularis jumonji domain containing 1A 0.0025 0.0039 0.0069
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0192 0.0677 0.1298
Leishmania major cathepsin L-like protease 0.0017 0.0008 0.0005
Echinococcus multilocularis serotonin receptor 0.018 0.0634 0.1215
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.0041
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0103 0.0275
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0426
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0087 0.0161
Echinococcus granulosus lysine specific demethylase 6a 0.0025 0.0039 0.0069
Schistosoma mansoni hypothetical protein 0.003 0.0058 0.0105
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0084 0.0224
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0046 0.0082
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0008 0.0009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1047 0.2883
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0013
Onchocerca volvulus 0.0055 0.0156 0.0422
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0017 0.0014
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0017 0.004
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0026 0.0045 0.0117
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.0958 0.2636
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0192 0.0677 0.2493
Loa Loa (eye worm) hypothetical protein 0.0084 0.0266 0.074
Leishmania major short chain dehydrogenase-like protein 0.0019 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0025 0.0039 0.01
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1047 0.2883
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0017 0.0051
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0055 0.0156 0.0295
Leishmania major short chain dehydrogenase, putative 0.0019 0.0017 0.0014
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0019 0.0017 0.0051
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0057 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0049 0.0126
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0174 0.0498
Echinococcus multilocularis GPCR, family 2 0.0016 0.0005 0.0003
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.012 0.1121
Echinococcus granulosus g protein coupled receptor 0.0055 0.0156 0.0295
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0055 0.0143
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0152
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Loa Loa (eye worm) hypothetical protein 0.0037 0.0087 0.0234
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0085 0.0226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0095 0.0253
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0155 0.0537 0.1028
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0019 0.0017 0.0036
Mycobacterium tuberculosis Probable dehydrogenase 0.0019 0.0017 0.004
Onchocerca volvulus 0.0019 0.0017 0.0038
Schistosoma mansoni retinal dehydrogenase 0.0019 0.0017 0.0027
Echinococcus granulosus fmrfamide receptor 0.0055 0.0156 0.0295
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0114 0.038 0.1061
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0027 0.0065
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0058 0.0164 0.031
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0044 0.0041
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0355 0.1132
Onchocerca volvulus Dual oxidase homolog 0.007 0.0213 0.0577
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0192 0.0677 0.6458
Loa Loa (eye worm) hypothetical protein 0.0026 0.0045 0.0117
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0125 0.0424 0.1183
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.0077 0.0215
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0039 0.01
Onchocerca volvulus 0.0096 0.0311 0.085
Schistosoma mansoni single-minded 0.0097 0.0317 0.0603
Schistosoma mansoni inositol monophosphatase 0.0148 0.0511 0.0977
Trypanosoma brucei protein kinase, putative 0.0101 0.0332 0.0329
Echinococcus granulosus hyperpolarization activated cyclic 0.0018 0.0013 0.002
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0108 0.0356 0.1004
Leishmania major hypothetical protein, conserved 0.0025 0.0039 0.0036
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0192 0.0677 0.2493
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Schistosoma mansoni jumonji domain containing protein 0.0025 0.0039 0.0069
Echinococcus granulosus neuropeptide Y receptor 0.0055 0.0156 0.0295
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0403 0.1485 0.422
Brugia malayi TAR-binding protein 0.0125 0.0424 0.1183
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0192 0.0677 0.0674
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0078 0.0206
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2629 1 1
Mycobacterium tuberculosis Carboxylesterase LipT 0.0108 0.0356 0.1004
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0085 0.0158
Echinococcus multilocularis serotonin receptor 0.018 0.0634 0.1215
Leishmania major hypothetical protein, conserved 0.0192 0.0677 0.0674
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0005 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0013
Brugia malayi jmjC domain containing protein 0.0025 0.0039 0.01
Loa Loa (eye worm) hypothetical protein 0.0108 0.0356 0.0993
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Leishmania major short chain dehydrogenase/reductase, putative 0.0019 0.0017 0.0014
Schistosoma mansoni ap endonuclease 0.0038 0.009 0.0166
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0192 0.0677 0.2493
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Onchocerca volvulus 0.0019 0.0017 0.0038
Echinococcus multilocularis 0.004 0.0096 0.0178
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0017 0.0014
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0017 0.0051
Onchocerca volvulus 0.0068 0.0205 0.0556
Brugia malayi Cathepsin L-like precursor 0.0017 0.0008 0.0013
Echinococcus granulosus allatostatin A receptor 0.0055 0.0156 0.0295
Onchocerca volvulus 0.0055 0.0156 0.0422
Onchocerca volvulus 0.0055 0.0156 0.0422
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0148 0.0511 0.1835
Echinococcus granulosus sex peptide receptor 0.0055 0.0156 0.0295
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0033 0.007 0.0067
Brugia malayi Inositol monophosphatase family protein 0.0016 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.0172 0.0601 0.115
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0187 0.0184
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0019 0.0017 0.0038
Plasmodium falciparum glutathione reductase 0.091 0.3424 1
Brugia malayi 6-phosphofructokinase 0.0108 0.0356 0.0992
Plasmodium falciparum phd finger protein, putative 0.0029 0.0054 0.0144
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Schistosoma mansoni neuropeptide receptor 0.0055 0.0156 0.0295
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1047 0.2883
Leishmania major hypothetical protein, conserved 0.0019 0.0017 0.0014
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0192 0.0677 0.1897
Brugia malayi hypothetical protein 0.0055 0.0156 0.0431
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0019 0.0017 0.004
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0027 0.0045
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0005 0.0003
Giardia lamblia Reductase, putative 0.0019 0.0017 0.0051
Echinococcus granulosus neuropeptide s receptor 0.0055 0.0156 0.0295
Brugia malayi neuropeptide F receptor 0.0055 0.0156 0.0431
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0265 0.0958 0.2686
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0121 0.0408 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0039 0.0099
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0041 0.0106
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0001
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.004 0.0096 0.0263
Onchocerca volvulus Subfamily M14A unassigned peptidase homolog 0.0068 0.0205 0.0556
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0019 0.0017 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0187 0.0184
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0192 0.0677 0.192
Plasmodium falciparum JmjC domain-containing protein, putative 0.0025 0.0039 0.0099
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0008 0.0009
Schistosoma mansoni amine GPCR 0.0055 0.0156 0.0295
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0005 0.0003
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0055 0.0191
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0013
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0114 0.038 0.1073
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0026 0.0045 0.008
Echinococcus granulosus neuropeptide Y receptor 0.0055 0.0156 0.0295
Loa Loa (eye worm) hypothetical protein 0.0157 0.0543 0.152
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0055 0.0156 0.0295
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0148 0.0511 0.1402
Brugia malayi Cytochrome P450 family protein 0.004 0.0096 0.026
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0192 0.0677 0.2493
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0005 0.0005
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0108 0.0356 0.0993
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0085 0.0082
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0026 0.0045 0.0153
Schistosoma mansoni hypothetical protein 0.003 0.0058 0.0105
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.004 0.0096 0.0341
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0192 0.0677 0.2493
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Loa Loa (eye worm) cytochrome P450 0.004 0.0096 0.026
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0028 0.005 0.0091
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.004 0.0096 0.0263
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0025 0.0039 0.0069
Schistosoma mansoni biogenic amine receptor 0.0055 0.0156 0.0295
Brugia malayi hypothetical protein 0.0055 0.0156 0.0431
Loa Loa (eye worm) hypothetical protein 0.0086 0.0274 0.0762
Echinococcus multilocularis neuropeptide s receptor 0.0055 0.0156 0.0295
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0084 0.0224
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0025 0.0039 0.0104
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0191 0.0361
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0019 0.0017 0.0014
Echinococcus multilocularis lipoxygenase domain containing protein 0.0157 0.0543 0.104
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0156 0.0295
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0174 0.0171
Loa Loa (eye worm) hypothetical protein 0.0192 0.0677 0.1897
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0174 0.0328
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.0045 0.0121
Loa Loa (eye worm) hypothetical protein 0.0026 0.0045 0.0117
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0017 0.0051
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.009 0.0238
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0055 0.0156 0.0422
Onchocerca volvulus 0.0108 0.0356 0.0974
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0171 0.0473
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Onchocerca volvulus 0.0133 0.0451 0.1236
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0019 0.0017 0.0014
Leishmania major 3-keto-dihydrosphingosine reductase 0.0019 0.0017 0.0014
Onchocerca volvulus 0.0026 0.0045 0.0114
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0078 0.0213
Plasmodium vivax vivapain-2 0.0017 0.0008 0.0023
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0016 0.0003 0.0001
Onchocerca volvulus 0.0963 0.3625 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0027 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0049 0.0128
Echinococcus multilocularis nuclear factor of activated T cells 5 0.015 0.0519 0.0992
Loa Loa (eye worm) hypothetical protein 0.0055 0.0156 0.0431
Brugia malayi hypoxia-induced factor 1 0.0302 0.1097 0.3079
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0511 0.0508
Mycobacterium ulcerans monoxygenase 0.0192 0.0677 0.2493
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0017 0.0027
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0017 0.004
Schistosoma mansoni hypothetical protein 0.0055 0.0156 0.0295
Loa Loa (eye worm) peptidase family M13 containing protein 0.0084 0.0266 0.074

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 2.5 nM Inhibition of human recombinant ACE2 by fluorescence assay ChEMBL. 18243695
Ki (binding) = 180 nM Inhibition of human recombinant NEP by fluorescence assay ChEMBL. 18243695
Ki (binding) = 4000 nM Inhibition of human recombinant ACE by fluorescence assay ChEMBL. 18243695
Ki (binding) = 16000 nM Inhibition of human recombinant CpA by fluorescence assay ChEMBL. 18243695
Ki app (binding) = 2.5 nM Inhibition of human recombinant ACE2 by fluorescence assay ChEMBL. 18243695
Ki app (binding) = 180 nM Inhibition of human recombinant NEP by fluorescence assay ChEMBL. 18243695
Ki app (binding) = 4000 nM Inhibition of human recombinant ACE by fluorescence assay ChEMBL. 18243695
Ki app (binding) = 16000 nM Inhibition of human recombinant CpA by fluorescence assay ChEMBL. 18243695
Papp (ADMET) = 5 nm/s Apparent permeability across human MDCK cells ChEMBL. 18243695

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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