Detailed information for compound 506269

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 586.6 | Formula: C29H26F4N4O3S
  • H donors: 0 H acceptors: 5 LogP: 4.87 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: N#Cc1ccc(cc1)n1c(nc2c1cccc2)[C@H](N(C(=O)Cc1ccc(c(c1)C(F)(F)F)F)CCS(=O)(=O)CC)C
  • InChi: 1S/C29H26F4N4O3S/c1-3-41(39,40)15-14-36(27(38)17-21-10-13-24(30)23(16-21)29(31,32)33)19(2)28-35-25-6-4-5-7-26(25)37(28)22-11-8-20(18-34)9-12-22/h4-13,16,19H,3,14-15,17H2,1-2H3/t19-/m1/s1
  • InChiKey: CCUSUVZCBYDCHA-LJQANCHMSA-N  

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens chemokine (C-X-C motif) receptor 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) intermediate filament protein 0.0059 0.0136 0.0402
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0027 0.0023 0.0029
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0209 0.0661 0.0846
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0017
Brugia malayi jmjC domain containing protein 0.0027 0.0023 0.0067
Echinococcus multilocularis somatostatin receptor 0.0063 0.0149 0.0191
Plasmodium vivax SET domain protein, putative 0.0093 0.0257 0.0755
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0109 0.031 0.0309
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0006 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2414 0.839 0.839
Echinococcus granulosus steroid dehydrogenase 0.002 0.0001 0.0001
Brugia malayi hypothetical protein 0.0063 0.0149 0.0441
Loa Loa (eye worm) hypothetical protein 0.0519 0.1747 0.5159
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0286 0.0366
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0152 0.0463 0.1721
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0583 0.217
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0009 0.0011
Brugia malayi Carboxylesterase family protein 0.0422 0.141 0.4163
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Loa Loa (eye worm) hypothetical protein 0.0225 0.0719 0.2123
Echinococcus granulosus dro:myosuppressin receptor 0.0063 0.0149 0.0191
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0271
Schistosoma mansoni hypothetical protein 0.0063 0.0149 0.0191
Loa Loa (eye worm) hepatopoietin HPO2 0.0037 0.006 0.0177
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0058 0.0214
Brugia malayi intermediate filament protein 0.0059 0.0136 0.0402
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0017
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0786 0.2684 0.3435
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0045 0.0087 0.0319
Echinococcus granulosus aryl hydrocarbon receptor 0.0041 0.0075 0.0095
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0035 0.0052 0.0146
Loa Loa (eye worm) G-protein coupled receptor 0.0063 0.0149 0.0441
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0149 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0078 0.0285
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0149 0.0191
Echinococcus granulosus snurportin 1 0.0328 0.1079 0.1382
Loa Loa (eye worm) hypothetical protein 0.0071 0.018 0.053
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.0076 0.0224
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0023 0.0022
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0109 0.031 0.0309
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0286 0.1061
Loa Loa (eye worm) jmjC domain-containing protein 0.01 0.0279 0.0823
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0187 0.0693
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0059 0.0136 0.0402
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0035 0.0052 0.0146
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0087 0.0256
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0035 0.0052 0.0189
Mycobacterium ulcerans dehydrogenase 0.0209 0.0661 0.2458
Brugia malayi ecdysteroid receptor 0.0022 0.0006 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0257 0.0329
Brugia malayi hypothetical protein 0.0125 0.0368 0.1086
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0003
Brugia malayi Cytochrome P450 family protein 0.0045 0.0087 0.0256
Echinococcus multilocularis G protein coupled receptor 139 0.0063 0.0149 0.0191
Brugia malayi hypothetical protein 0.0039 0.0066 0.0196
Schistosoma mansoni ankyrin 23/unc44 0.0031 0.004 0.0051
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0017
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.0063 0.0081
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Echinococcus multilocularis Ankyrin 0.0032 0.0041 0.0052
Brugia malayi Doublecortin family protein 0.0125 0.0368 0.1086
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0257 0.0329
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0011 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0032 0.0116
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0926 0.3448
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0049 0.0103 0.0102
Brugia malayi nuclear receptor NHR-88 0.0022 0.0006 0.0017
Trypanosoma brucei polo-like protein kinase 0.0102 0.0286 0.0285
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0006 0.0017
Onchocerca volvulus 0.0225 0.0719 0.2841
Giardia lamblia Kinase, CMGC MAPK 0.0109 0.031 0.1155
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0786 0.2684 0.7925
Leishmania major DNA polymerase eta, putative 0.0048 0.0097 0.0096
Trypanosoma cruzi target of rapamycin kinase 3 0.0039 0.0068 0.0066
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0035 0.0052 0.0189
Schistosoma mansoni steroid dehydrogenase 0.002 0.0001 0.0001
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0071 0.018 0.0665
Giardia lamblia Thioredoxin reductase 0.0209 0.0661 0.2461
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0209 0.0661 0.0846
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Plasmodium vivax thioredoxin reductase, putative 0.0986 0.3386 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0071 0.018 0.023
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0035 0.0052 0.0189
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0081 0.0212 0.0627
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0038 0.0112
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.0138
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0331 0.0424
Schistosoma mansoni lamin 0.0059 0.0136 0.0174
Brugia malayi oxidoreductase 0.002 0.0001 0.0003
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0324 0.1066 0.3148
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.002 0.0001 0.0001
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0786 0.2684 0.7718
Echinococcus granulosus BC026374 protein S09 family 0.0071 0.018 0.023
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0027 0.0023 0.0067
Toxoplasma gondii hypothetical protein 0.0038 0.0063 0.0187
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0786 0.2684 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0038 0.0109
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0027 0.0023 0.0029
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0164 0.0504 0.0645
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Toxoplasma gondii target of rapamycin (TOR), putative 0.0037 0.0058 0.0173
Trypanosoma brucei DNA polymerase eta, putative 0.0048 0.0097 0.0096
Trypanosoma brucei protein kinase, putative 0.0109 0.031 0.0309
Echinococcus multilocularis fmrfamide receptor 0.0063 0.0149 0.0191
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1021 0.3803
Echinococcus granulosus sodium and chloride dependent glycine 0.0038 0.0063 0.0081
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0225 0.0719 0.2123
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.2107 0.7313 0.7313
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0209 0.0661 0.6464
Schistosoma mansoni neuroligin 3 (S09 family) 0.0071 0.018 0.023
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0006 0.0007
Schistosoma mansoni hypothetical protein 0.0051 0.0108 0.0138
Echinococcus granulosus lipoxygenase domain containing protein 0.0125 0.0368 0.0471
Echinococcus granulosus death domain containing protein 0.0031 0.004 0.0051
Plasmodium vivax JmjC domain containing protein 0.0027 0.0023 0.0064
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0191 0.06 0.0768
Schistosoma mansoni intermediate filament proteins 0.0059 0.0136 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0023 0.0082
Loa Loa (eye worm) hypothetical protein 0.0041 0.0075 0.022
Toxoplasma gondii selenide, water dikinase 0.0209 0.0661 0.1951
Schistosoma mansoni blooms syndrome DNA helicase 0.0038 0.0064 0.0082
Loa Loa (eye worm) hypoxia-induced factor 1 0.0493 0.1657 0.4894
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0102 0.0286 0.0366
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0209 0.0661 0.1951
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0209 0.0661 0.2458
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0191 0.06 0.0768
Echinococcus multilocularis neuropeptides capa receptor 0.0063 0.0149 0.0191
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0187
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0063 0.0149 0.0191
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Entamoeba histolytica hypothetical protein 0.0039 0.0066 0.0639
Schistosoma mansoni coup transcription factor 0.0022 0.0006 0.0007
Brugia malayi jmjC domain containing protein 0.0027 0.0023 0.0067
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0209 0.0661 0.2458
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.0331 0.1108
Trypanosoma cruzi NADH dehydrogenase, putative 0.0209 0.0661 0.066
Schistosoma mansoni lamin 0.0059 0.0136 0.0174
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.004 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0103 0.038
Treponema pallidum sodium- and chloride- dependent transporter 0.0225 0.0719 0.2573
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0038 0.0113
Schistosoma mansoni jumonji domain containing protein 0.0027 0.0023 0.0029
Schistosoma mansoni protein phosphatase 2C 0.0027 0.0023 0.0029
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0405 0.135 0.1349
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0009 0.0026
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.0076 0.0278
Schistosoma mansoni sulfide quinone reductase 0.0209 0.0661 0.0846
Echinococcus granulosus lamin 0.0059 0.0136 0.0174
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.031 0.1152
Trypanosoma cruzi polo-like protein kinase, putative 0.0102 0.0286 0.0285
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0002 0.0002
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0069 0.017 0.0503
Loa Loa (eye worm) glutathione reductase 0.0986 0.3386 1
Schistosoma mansoni opsin-like receptor 0.0063 0.0149 0.0191
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0006 0.0007
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0209 0.0661 0.066
Leishmania major hypothetical protein, conserved 0.0027 0.0023 0.0022
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0171 0.0529 0.1561
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0081 0.0212 0.0788
Brugia malayi G protein-coupled receptor 0.0063 0.0149 0.0441
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.017 0.0218
Trypanosoma brucei trypanothione reductase 0.0986 0.3386 0.3385
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0209 0.0661 0.0846
Schistosoma mansoni sodium/chloride dependent transporter 0.0038 0.0063 0.0081
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0331 0.0978
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0001 0.0001
Treponema pallidum fructose-bisphosphate aldolase 0.0312 0.1021 0.3716
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Treponema pallidum NADH oxidase 0.0786 0.2684 1
Giardia lamblia Reductase, putative 0.002 0.0001 0.0004
Brugia malayi hypothetical protein 0.0063 0.0149 0.0441
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0035 0.0052 0.0189
Echinococcus multilocularis carboxylesterase 5A 0.0422 0.141 0.1804
Entamoeba histolytica recQ family helicase, putative 0.0026 0.0021 0.0193
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Plasmodium vivax amine transporter, putative 0.0038 0.0063 0.0184
Loa Loa (eye worm) norepinephrine transporter 0.0225 0.0719 0.2123
Onchocerca volvulus 0.0161 0.0494 0.1951
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0052 0.0146
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Loa Loa (eye worm) hypothetical protein 0.0315 0.1035 0.3056
Echinococcus granulosus neuropeptide Y receptor 0.0063 0.0149 0.0191
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0209 0.0661 0.1951
Brugia malayi ORL1-like opioid receptor 0.0063 0.0149 0.0441
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0076 0.0221
Mycobacterium leprae putative cytochrome p450 0.0035 0.0052 0.0146
Brugia malayi RE15519p 0.0063 0.0149 0.0441
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0042 0.0076 0.0278
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0209 0.0661 0.066
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0209 0.0661 0.1951
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.0619 0.2302
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0023 0.0067
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.012
Echinococcus multilocularis acetylcholinesterase 0.0422 0.141 0.1804
Schistosoma mansoni adenoreceptor 0.0063 0.0149 0.0191
Echinococcus granulosus netrin receptor unc 5 0.0031 0.004 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0006 0.0017
Brugia malayi Intermediate filament tail domain containing protein 0.0059 0.0136 0.0402
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0066 0.0085
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0209 0.0661 0.1897
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0164 0.0504 0.0645
Echinococcus multilocularis sex peptide receptor 0.0063 0.0149 0.0191
Schistosoma mansoni steroid dehydrogenase 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0009 0.0026
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0037 0.006 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.031 0.0397
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0209 0.0661 0.066
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0191 0.06 0.1773
Treponema pallidum oxidoreductase 0.0209 0.0661 0.2353
Trichomonas vaginalis guanylate cyclase, putative 0.0041 0.0075 0.0274
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0209 0.0661 0.066
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0063 0.0149 0.0191
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2414 0.839 0.839
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0152 0.0463 0.1328
Brugia malayi PAS domain containing protein 0.0159 0.0488 0.144
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0006 0.0007
Echinococcus granulosus intermediate filament protein 0.0059 0.0136 0.0174
Schistosoma mansoni growth hormone secretagogue receptor 0.0063 0.0149 0.0191
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0001 0.0001
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0071 0.018 0.053
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1021 0.3803
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0209 0.0661 0.1897
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Brugia malayi glutathione reductase 0.0986 0.3386 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0038 0.0063 0.0081
Loa Loa (eye worm) hypothetical protein 0.007 0.0174 0.0514
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0035 0.0052 0.0146
Onchocerca volvulus 0.0071 0.018 0.0707
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0043 0.0079 0.0078
Loa Loa (eye worm) inositol-1 0.0081 0.0212 0.0627
Echinococcus granulosus dna polymerase kappa 0.0021 0.0002 0.0002
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0063 0.0149 0.0191
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Schistosoma mansoni cytochrome P450 0.0035 0.0052 0.0066
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0052 0.011 0.0325
Echinococcus granulosus tachykinin peptides receptor 99D 0.0063 0.0149 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0075 0.0274
Echinococcus granulosus lysine specific demethylase 6a 0.0027 0.0023 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0023 0.0082
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0009 0.0008
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.0063 0.0187
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0113
Loa Loa (eye worm) cytochrome P450 family protein 0.0057 0.0128 0.0377
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0038 0.0063 0.0081
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0038 0.0063 0.0096
Loa Loa (eye worm) CYP4Cod1 0.0045 0.0087 0.0256
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0651 0.2211 0.6529
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0003
Onchocerca volvulus 0.0022 0.0006 0.0018
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0076 0.0224
Brugia malayi Inositol-1 0.0081 0.0212 0.0627
Onchocerca volvulus 0.0038 0.0063 0.0247
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Schistosoma mansoni jun-related protein 0.022 0.0701 0.0897
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0184 0.0573 0.0572
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0154 0.0197
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0209 0.0661 0.1897
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0006 0.0007
Trypanosoma cruzi trypanothione reductase, putative 0.0986 0.3386 0.3385
Echinococcus granulosus neuropeptide FF receptor 2 0.0063 0.0149 0.0191
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.0063 0.0081
Echinococcus granulosus neuropeptides capa receptor 0.0063 0.0149 0.0191
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.0443 0.0442
Schistosoma mansoni hypothetical protein 0.0328 0.1079 0.1382
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0031 0.004 0.0051
Plasmodium falciparum phd finger protein, putative 0.0031 0.0038 0.0113
Brugia malayi chromobox protein homolog 3 0.0041 0.0074 0.0218
Schistosoma mansoni tar DNA-binding protein 0.0069 0.017 0.0218
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0063 0.0149 0.0191
Trypanosoma cruzi hypothetical protein, conserved 0.0209 0.0661 0.066
Schistosoma mansoni hypothetical protein 0.0109 0.031 0.0397
Mycobacterium tuberculosis Probable dehydrogenase 0.0435 0.1454 0.4179
Loa Loa (eye worm) G-protein coupled receptor 0.0063 0.0149 0.0441
Schistosoma mansoni amine GPCR 0.0063 0.0149 0.0191
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.0063 0.0187
Brugia malayi glutamate synthase 0.0209 0.0661 0.1951
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0214 0.0681 0.0871
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0209 0.0661 0.1948
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0035 0.0052 0.0146
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0049 0.0103 0.0132
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.0149 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0058 0.0214
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Trypanosoma cruzi polo-like protein kinase, putative 0.0102 0.0286 0.0285
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0038 0.0138
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0081 0.0212 0.0211
Echinococcus multilocularis sodium channel protein 0.013 0.0385 0.0493
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2107 0.7313 0.7313
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0035 0.0052 0.0146
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0035 0.0052 0.0146
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0035 0.0052 0.0146
Plasmodium falciparum thioredoxin reductase 0.0986 0.3386 1
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0583 0.217
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0209 0.0661 0.1951
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.002 0.0001 0.0003
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0043 0.0079 0.0078
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0209 0.0661 0.0846
Echinococcus multilocularis mitogen activated protein kinase 3 0.0109 0.031 0.0397
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0087 0.0085
Echinococcus multilocularis GPCR, family 2 0.0051 0.0108 0.0138
Schistosoma mansoni hypothetical protein 0.0051 0.0108 0.0138
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0063 0.0149 0.0191
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Treponema pallidum thioredoxin reductase (trxB) 0.0209 0.0661 0.2353
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.0138
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0049 0.0103 0.0132
Echinococcus multilocularis lamin 0.0059 0.0136 0.0174
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0006 0.0017
Schistosoma mansoni gliotactin 0.0071 0.018 0.023
Echinococcus multilocularis netrin receptor unc 5 0.0031 0.004 0.0051
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0187
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0328 0.1079 0.3187
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.017 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0033 0.0119
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Echinococcus multilocularis neuropeptide Y receptor 0.0063 0.0149 0.0191
Echinococcus granulosus peptide allatostatin:somatostatin 0.0063 0.0149 0.0191
Echinococcus granulosus oxidoreductase 0.002 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0035 0.0052 0.0189
Trypanosoma cruzi DNA polymerase eta, putative 0.0048 0.0097 0.0096
Brugia malayi Importin beta-1 subunit 0.0031 0.0037 0.011
Onchocerca volvulus 0.0063 0.0149 0.0587
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0435 0.1454 0.4179
Brugia malayi Retinol dehydrogenase 12 0.002 0.0001 0.0003
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0081 0.0212 0.0788
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.0076 0.0075
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0209 0.0661 0.0846
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Brugia malayi G protein-coupled receptor F59B2.13 0.0063 0.0149 0.0441
Brugia malayi GnHR receptor homolog 0.0063 0.0149 0.0441
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0017
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.0063 0.0187
Schistosoma mansoni alpha-1 adrenergic receptor 0.0063 0.0149 0.0191
Brugia malayi bZIP transcription factor family protein 0.0271 0.0879 0.2596
Echinococcus granulosus bloom syndrome protein 0.0049 0.01 0.0128
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1021 0.3803
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0093 0.0257 0.0758
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0209 0.0661 0.066
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.01 0.0128
Echinococcus granulosus lamin dm0 0.0059 0.0136 0.0174
Echinococcus granulosus RUN 0.0125 0.0368 0.0471
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0037 0.006 0.0059
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0209 0.0661 0.0846
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0035 0.0052 0.0189
Onchocerca volvulus 0.0063 0.0149 0.0587
Schistosoma mansoni steroid dehydrogenase 0.002 0.0001 0.0001
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0209 0.0661 0.066
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0443 0.0442
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0037 0.0048
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0435 0.1454 0.4179
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0209 0.0661 0.2458
Schistosoma mansoni survival motor neuron protein 0.0102 0.0289 0.037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0023 0.0082
Brugia malayi sulfakinin receptor protein 0.0063 0.0149 0.0441
Echinococcus multilocularis g protein coupled receptor 0.0063 0.0149 0.0191
Brugia malayi hypothetical protein 0.0054 0.0117 0.0347
Trypanosoma cruzi NADH dehydrogenase, putative 0.0209 0.0661 0.066
Schistosoma mansoni glutamate synthase 0.0209 0.0661 0.0846
Echinococcus granulosus mitogen activated protein kinase 0.0109 0.031 0.0397
Toxoplasma gondii oxidoreductase, putative 0.002 0.0001 0.0003
Trichomonas vaginalis ran, putative 0.0023 0.0009 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.031 0.1152
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0006 0.0017
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Plasmodium falciparum steroid dehydrogenase, putative 0.002 0.0001 0.0003
Schistosoma mansoni phd/f-box containing protein 0.0027 0.0023 0.0029
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.002 0.0001 0.0001
Brugia malayi latrophilin 2 splice variant baaae 0.011 0.0315 0.093
Brugia malayi hypothetical protein 0.0035 0.0051 0.015
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.002 0.0001 0.0003
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0006 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0058 0.0214
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.017 0.0218
Loa Loa (eye worm) hypothetical protein 0.0059 0.0136 0.0402
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0209 0.0661 0.0846
Schistosoma mansoni glutamate synthase 0.0209 0.0661 0.0846
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0786 0.2684 0.7925
Schistosoma mansoni sodium/chloride dependent transporter 0.0225 0.0719 0.092
Loa Loa (eye worm) hypothetical protein 0.0147 0.0446 0.1316
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0063 0.0149 0.0191
Brugia malayi Serotonin receptor 0.0063 0.0149 0.0441
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0075 0.0073
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0209 0.0661 0.1897
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0209 0.0661 0.2458
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0284 0.0926 0.2735
Schistosoma mansoni carbonyl reductase 0.002 0.0001 0.0001
Echinococcus multilocularis Polycystic kidney disease protein 0.0125 0.0368 0.0471
Schistosoma mansoni short-chain dehydrogenase/reductase 0.002 0.0001 0.0001
Onchocerca volvulus Serine\/threonine kinase homolog 0.0102 0.0286 0.1127
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.002 0.0001 0.0001
Echinococcus multilocularis musashi 0.0059 0.0136 0.0174
Treponema pallidum exodeoxyribonuclease (exoA) 0.0042 0.0076 0.0143
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0063 0.0149 0.0191
Schistosoma mansoni polycystin 1-related 0.0125 0.0368 0.0471
Plasmodium falciparum glutathione reductase 0.0786 0.2684 0.7925
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0187
Trichomonas vaginalis spcc417.12 protein, putative 0.0071 0.018 0.0665
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0149 0.0191
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1021 0.3803
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0154 0.0153
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1021 0.3803
Onchocerca volvulus 0.0125 0.0368 0.1452
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Brugia malayi dehydrogenases, short chain protein 9 0.002 0.0001 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0006 0.0017
Onchocerca volvulus 0.0125 0.0368 0.1452
Echinococcus granulosus acetylcholinesterase 0.0422 0.141 0.1804
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0116 0.0114
Echinococcus granulosus 7tm_1 domain containing protein 0.0063 0.0149 0.0191
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.0076 0.0097
Brugia malayi hypothetical protein 0.0063 0.0149 0.0441
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0117 0.0116
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0286 0.1061
Brugia malayi Pre-SET motif family protein 0.0651 0.2211 0.6529
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0038 0.0112
Trichomonas vaginalis DNA helicase recq1, putative 0.0049 0.01 0.037
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0482 0.1617 0.207
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0209 0.0661 0.2458
Echinococcus multilocularis JmjC domain containing protein 4 0.0027 0.0023 0.0029
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0017
Schistosoma mansoni carbonyl reductase 0.002 0.0001 0.0001
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Brugia malayi Tachykinin-like peptides receptor 99D 0.0063 0.0149 0.0441
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0331 0.1231
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0209 0.0661 0.066
Schistosoma mansoni lipoxygenase 0.0482 0.1617 0.207
Brugia malayi hypothetical protein 0.0038 0.0063 0.0187
Plasmodium falciparum thioredoxin reductase 0.0786 0.2684 0.7925
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0006 0.0017
Brugia malayi Serotonin receptor 0.0569 0.1925 0.5684
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0035 0.0052 0.0146
Onchocerca volvulus 0.0118 0.0343 0.1352
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.0149 0.0191
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0003
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0103 0.038
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0006 0.0007
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0209 0.0661 0.1897
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0058 0.0214
Schistosoma mansoni sulfide quinone reductase 0.0209 0.0661 0.0846
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0075 0.0274
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0331 0.3236
Schistosoma mansoni myosin xvIII 0.0063 0.0149 0.0191
Onchocerca volvulus 0.0063 0.0149 0.0587
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0038 0.0063 0.0081
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0154 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0032 0.0114
Echinococcus granulosus survival motor neuron protein 1 0.0502 0.169 0.2164
Echinococcus granulosus jumonji domain containing 1A 0.0027 0.0023 0.0029
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0926 0.3448
Brugia malayi dehydrogenases, short chain protein 2 0.002 0.0001 0.0003
Echinococcus granulosus phd:f box containing protein 0.0027 0.0023 0.0029
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0786 0.2684 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Onchocerca volvulus 0.0063 0.0149 0.0587
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0786 0.2684 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0209 0.0661 0.1951
Onchocerca volvulus 0.0102 0.0289 0.1139
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0071 0.018 0.023
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0032 0.0041 0.0052
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0003
Brugia malayi MAP kinase sur-1 0.0109 0.031 0.0916
Echinococcus multilocularis retinol dehydrogenase 13 0.002 0.0001 0.0001
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0071 0.018 0.023
Loa Loa (eye worm) hypothetical protein 0.0324 0.1066 0.3148
Leishmania major protein kinase, putative 0.0048 0.0098 0.0097
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0149 0.0191
Mycobacterium ulcerans hypothetical protein 0.0209 0.0661 0.2458
Brugia malayi cytochrome P450 0.0035 0.0052 0.0153
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0154 0.0454
Onchocerca volvulus 0.0071 0.018 0.0707
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.0331 0.095
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0006 0.0007
Schistosoma mansoni aryl hydrocarbon receptor 0.0159 0.0488 0.0624
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.006 0.0174
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.017 0.0502
Loa Loa (eye worm) neuropeptide F receptor 0.0063 0.0149 0.0441
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0102 0.0286 0.0844
Loa Loa (eye worm) hypothetical protein 0.0046 0.0092 0.0271
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0154 0.0197
Schistosoma mansoni steroid dehydrogenase 0.002 0.0001 0.0001
Schistosoma mansoni phosphatidylserine receptor 0.0027 0.0023 0.0029
Mycobacterium tuberculosis Carboxylesterase LipT 0.0071 0.018 0.0514
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0067
Mycobacterium leprae Possible regulatory protein 0.0041 0.0075 0.0211
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0583 0.217
Entamoeba histolytica serine/threonine protein kinase, putative 0.0102 0.0286 0.2791
Onchocerca volvulus 0.0063 0.0149 0.0587
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0331 0.0424
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.0117 0.0116
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0063 0.0149 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0075 0.0274
Schistosoma mansoni biogenic amine (5HT) receptor 0.0063 0.0149 0.0191
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0435 0.1454 0.4179
Brugia malayi hypoxia-induced factor 1 0.0493 0.1657 0.4894
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0067 0.0247
Schistosoma mansoni single-minded 0.0159 0.0488 0.0624
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0035 0.0052 0.0146
Schistosoma mansoni sodium-dependent amino acid transporter 0.0038 0.0063 0.0081
Schistosoma mansoni steroid dehydrogenase 0.002 0.0001 0.0001
Schistosoma mansoni amine GPCR 0.0063 0.0149 0.0191
Brugia malayi RNA binding protein 0.0069 0.017 0.0503
Brugia malayi TAR-binding protein 0.0069 0.017 0.0503
Echinococcus multilocularis microtubule associated protein 2 0.2249 0.7812 1
Plasmodium falciparum JmjC domain-containing protein, putative 0.0027 0.0023 0.0067
Loa Loa (eye worm) hypothetical protein 0.0054 0.0117 0.0347
Trichomonas vaginalis DNA helicase recq, putative 0.0026 0.0021 0.0073
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0405 0.135 0.3988
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0149 0.0191
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0017 0.0059
Echinococcus multilocularis neuropeptide Y receptor 0.0063 0.0149 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0046 0.0167
Toxoplasma gondii thioredoxin reductase 0.0986 0.3386 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0125 0.0368 0.0471
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0115 0.0331 0.095
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0184 0.0573 0.1646
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0187 0.0552
Trypanosoma brucei cytochrome P450, putative 0.0045 0.0087 0.0085
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0331 0.1231
Mycobacterium ulcerans NADH dehydrogenase 0.0209 0.0661 0.2458
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.002 0.0001 0.0003
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0109 0.031 0.0309
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0063 0.0149 0.0191
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Echinococcus granulosus histone lysine methyltransferase setb 0.0093 0.0257 0.0329
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Schistosoma mansoni histamine h1 receptor 0.0063 0.0149 0.0191
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0063 0.0149 0.0191
Brugia malayi Bloom's syndrome protein homolog 0.0049 0.01 0.0296
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0038 0.0063 0.0187
Echinococcus granulosus lipoxygenase domain containing protein 0.0125 0.0368 0.0471
Schistosoma mansoni tar DNA-binding protein 0.0069 0.017 0.0218
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0075
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.0076 0.0732
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0001 0.0004
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0041 0.0075 0.0274
Echinococcus multilocularis 0.0035 0.0052 0.0066
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0577 0.1953 0.5766
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1021 0.3803
Echinococcus multilocularis mitogen activated protein kinase 0.0109 0.031 0.0397
Brugia malayi Augmenter of liver regeneration 0.0037 0.006 0.0177
Schistosoma mansoni voltage-gated potassium channel 0.0055 0.0123 0.0158
Schistosoma mansoni neuropeptide F-like receptor 0.0063 0.0149 0.0191
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0006 0.0017
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Schistosoma mansoni hypothetical protein 0.0031 0.0038 0.0049
Echinococcus multilocularis transfer RNA-Lys 0.0118 0.0343 0.0439
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2874 1 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.0076 0.0097
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0071 0.018 0.0514
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.0331 0.0424
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0006 0.0007
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0191 0.06 0.2234
Onchocerca volvulus 0.0063 0.0149 0.0587
Schistosoma mansoni amine GPCR 0.0063 0.0149 0.0191
Echinococcus granulosus neuropeptide s receptor 0.0063 0.0149 0.0191
Loa Loa (eye worm) hypothetical protein 0.0225 0.0719 0.2123
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0014 0.0018
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0154 0.0197
Schistosoma mansoni neuropeptide receptor 0.0063 0.0149 0.0191
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0161 0.0493 0.1456
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0049 0.0103 0.0132
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0184 0.0573 0.0572
Onchocerca volvulus 0.0063 0.0149 0.0587
Loa Loa (eye worm) hypothetical protein 0.011 0.0315 0.093
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0117 0.0347
Schistosoma mansoni sodium/chloride dependent transporter 0.004 0.0068 0.0087
Onchocerca volvulus 0.0071 0.018 0.0707
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0209 0.0661 0.1897
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0577 0.1953 0.5766
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0001 0.0001
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0209 0.0661 0.2458
Entamoeba histolytica hypothetical protein 0.0039 0.0066 0.0639
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0286 0.1061
Schistosoma mansoni inositol monophosphatase 0.0081 0.0212 0.0272
Echinococcus multilocularis G-protein coupled receptor, putative 0.0063 0.0149 0.0191
Entamoeba histolytica hypothetical protein 0.0039 0.0066 0.0639
Loa Loa (eye worm) hypothetical protein 0.0207 0.0656 0.1936
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0037 0.006 0.0077
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0079 0.0078
Mycobacterium ulcerans glutamate synthase subunit beta 0.0209 0.0661 0.2458
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0063 0.0149 0.0191
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0011 0.0013
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0033 0.0045 0.013
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0006 0.0007
Trypanosoma brucei NADH dehydrogenase 0.0209 0.0661 0.066
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0011 0.001
Mycobacterium ulcerans ferredoxin reductase 0.0209 0.0661 0.2458
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0041 0.0075 0.0274
Schistosoma mansoni hypothetical protein 0.0051 0.0108 0.0138
Toxoplasma gondii Erv1 / Alr family protein 0.0037 0.006 0.0177
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0006 0.0007
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0035 0.0052 0.0051
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.01 0.0128
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0051 0.0108 0.0318
Brugia malayi RNA, U transporter 1 0.0087 0.0236 0.0696
Echinococcus granulosus lysine specific demethylase 5A 0.01 0.0279 0.0357
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0003
Schistosoma mansoni importin beta-1 0.0031 0.0037 0.0048
Brugia malayi hypothetical protein 0.0063 0.0149 0.0441
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0209 0.0661 0.1951
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0042 0.0153
Echinococcus granulosus Ankyrin 0.0032 0.0041 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0067 0.0247
Echinococcus multilocularis neuropeptide FF receptor 2 0.0063 0.0149 0.0191
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0082 0.0081
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Loa Loa (eye worm) hypothetical protein 0.0051 0.0108 0.0318
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0009 0.0026
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0075 0.0073
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0038 0.0142
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.0063 0.0081
Echinococcus granulosus serotonin receptor 0.0063 0.0149 0.0191
Echinococcus multilocularis serotonin receptor 0.0315 0.1035 0.1325
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.0076 0.0075
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0209 0.0661 0.2458
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0033 0.0044 0.0129
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0009 0.0008
Brugia malayi Cytochrome P450 family protein 0.0035 0.0052 0.0153
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0032 0.0116
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0063 0.0149 0.0191
Brugia malayi Carboxylesterase family protein 0.0071 0.018 0.053
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0209 0.0661 0.2458
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0037 0.011
Entamoeba histolytica disulphide oxidoreductase, putative 0.0209 0.0661 0.6464
Echinococcus granulosus hypothetical protein 0.002 0.0001 0.0001
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0786 0.2684 0.7925
Loa Loa (eye worm) hypothetical protein 0.0225 0.0719 0.2123
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0209 0.0661 0.066
Schistosoma mansoni neuropeptide receptor 0.0063 0.0149 0.0191
Echinococcus granulosus carbonyl reductase 1 0.002 0.0001 0.0001
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0038 0.0063 0.0081
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0075
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0786 0.2684 0.3435
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0075 0.0073
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0209 0.0661 0.2458
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0225 0.0719 0.092
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0063 0.0149 0.0441
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0035 0.0052 0.0189
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0331 0.1231
Echinococcus granulosus carbonyl reductase 1 0.002 0.0001 0.0001
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0038 0.0049
Brugia malayi hypothetical protein 0.002 0.0001 0.0003
Leishmania major hypothetical protein, conserved 0.0209 0.0661 0.066
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0975 0.3345 0.4282
Schistosoma mansoni hypothetical protein 0.022 0.0701 0.0897
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0047 0.0046
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0786 0.2684 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0063 0.0149 0.0191
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0085 0.0331
Brugia malayi hypothetical protein 0.0063 0.0149 0.0441
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0103 0.038
Entamoeba histolytica thioredoxin reductase, putative 0.0209 0.0661 0.6464
Plasmodium falciparum transporter, putative 0.0038 0.0063 0.0187
Echinococcus granulosus serotonin transporter 0.0225 0.0719 0.092
Echinococcus multilocularis snurportin 1 0.0328 0.1079 0.1382
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0063 0.0149 0.0191
Echinococcus multilocularis geminin 0.0376 0.1248 0.1597
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0081 0.0104
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0209 0.0661 0.0846
Echinococcus multilocularis chromobox protein 1 0.0073 0.0187 0.0239
Echinococcus granulosus chromobox protein 1 0.0073 0.0187 0.0239
Echinococcus granulosus thioredoxin glutathione reductase 0.0986 0.3386 0.4335
Schistosoma mansoni ap endonuclease 0.0042 0.0076 0.0097
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0209 0.0661 0.066
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.002 0.0001 0.0001
Mycobacterium ulcerans monoxygenase 0.0209 0.0661 0.2458
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.002 0.0001 0.0003
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0038 0.0109
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0093 0.0257 0.0329
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.0117 0.0343
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.002 0.0001 0.0001
Mycobacterium tuberculosis Conserved hypothetical protein 0.0163 0.0501 0.1439
Schistosoma mansoni loxhd1 0.0125 0.0368 0.0471
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0063 0.0149 0.0441
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0037 0.006 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0033 0.0119
Echinococcus multilocularis tar DNA binding protein 0.0069 0.017 0.0218
Mycobacterium ulcerans hypothetical protein 0.0163 0.0501 0.1865
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0209 0.0661 0.6464
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0058 0.0214
Loa Loa (eye worm) dehydrogenase 0.002 0.0001 0.0003
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0209 0.0661 0.1951
Schistosoma mansoni opsin-like receptor 0.0063 0.0149 0.0191
Brugia malayi Melatonin receptor type 1A 0.0063 0.0149 0.0441
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0001 0.0001
Echinococcus granulosus JmjC domain containing protein 4 0.0027 0.0023 0.0029
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0009 0.0033
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0271 0.0879 0.1125
Loa Loa (eye worm) hypothetical protein 0.0093 0.0257 0.0758
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0038 0.0063 0.0081
Onchocerca volvulus 0.0063 0.0149 0.0587
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0006 0.0017
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.002 0.0001 0.0001
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0245 0.0313
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0006 0.0017
Echinococcus multilocularis lysine specific demethylase 6a 0.0027 0.0023 0.0029
Onchocerca volvulus 0.0063 0.0149 0.0587
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0003
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0038 0.0063 0.0081
Toxoplasma gondii hypothetical protein 0.005 0.0105 0.0309
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0017
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0154 0.057
Schistosoma mansoni hypothetical protein 0.0376 0.1248 0.1597
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0035 0.0052 0.0189
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0081 0.0212 0.0211
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0009 0.0011
Onchocerca volvulus 0.0063 0.0149 0.0587
Echinococcus multilocularis peregrin 0.0031 0.0038 0.0049
Leishmania major cytochrome p450-like protein 0.0035 0.0052 0.0051
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.0063 0.0081
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0482 0.1617 0.207
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0079 0.0078
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0209 0.0661 0.1897
Echinococcus granulosus neuropeptide receptor 0.0063 0.0149 0.0191
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0003
Leishmania major C-8 sterol isomerase-like protein 0.0405 0.135 0.1349
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0003
Schistosoma mansoni steroid dehydrogenase 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0422 0.141 0.4163
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0534 0.1802 0.5322
Schistosoma mansoni acetylcholinesterase 0.0071 0.018 0.023
Onchocerca volvulus 0.0063 0.0149 0.0587
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0066 0.0085
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0003
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.0138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0067 0.0247
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0035 0.0052 0.0189
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0023 0.0011 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0108 0.0397
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0006 0.0007
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0029 0.0037
Echinococcus granulosus biogenic amine 5HT receptor 0.0315 0.1035 0.1325
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0209 0.0661 0.2458
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0312 0.1021 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0071 0.018 0.053
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0006 0.0017
Echinococcus multilocularis serotonin receptor 0.0315 0.1035 0.1325
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0038 0.011
Brugia malayi follicle stimulating hormone receptor 0.0063 0.0149 0.0441
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.0138
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.01 0.0128
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Echinococcus granulosus 7TM GPCR rhodopsin 0.0063 0.0149 0.0191
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0035 0.0052 0.0189
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.0063 0.0187
Toxoplasma gondii hypothetical protein 0.0038 0.0063 0.0187
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0038 0.0113
Onchocerca volvulus 0.0209 0.0661 0.2611
Schistosoma mansoni neuropeptide F-like receptor 0.0063 0.0149 0.0191
Loa Loa (eye worm) hypothetical protein 0.0071 0.018 0.053
Echinococcus granulosus transcription factor Dp 1 0.004 0.0069 0.0088
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2874 1 1
Echinococcus multilocularis acetylcholinesterase 0.0422 0.141 0.1804
Echinococcus multilocularis transient receptor potential cation channel 0.002 0.0001 0.0001
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0006 0.0018
Onchocerca volvulus 0.0063 0.0149 0.0587
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Toxoplasma gondii cytochrome p450 superfamily protein 0.0035 0.0052 0.0153
Echinococcus multilocularis neuroligin 0.0071 0.018 0.023
Onchocerca volvulus 0.0059 0.0136 0.0535
Loa Loa (eye worm) hypothetical protein 0.0263 0.0853 0.2519
Leishmania major hypothetical protein, conserved 0.0209 0.0661 0.066
Loa Loa (eye worm) hypothetical protein 0.0161 0.0494 0.1459
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0209 0.0661 0.2458
Echinococcus granulosus nuclear factor of activated T cells 5 0.0161 0.0494 0.0632
Echinococcus granulosus alpha 1A adrenergic receptor 0.0063 0.0149 0.0191
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0006 0.0007
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0209 0.0661 0.2458
Loa Loa (eye worm) hypothetical protein 0.0048 0.0097 0.0286
Echinococcus granulosus carbonyl reductase 1 0.002 0.0001 0.0001
Giardia lamblia Glutamate synthase 0.0209 0.0661 0.2461
Toxoplasma gondii carbonyl reductase 1, putative 0.002 0.0001 0.0003
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0109 0.031 0.0916
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0017 0.0059
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0063 0.0149 0.0441
Echinococcus granulosus acetylcholinesterase 0.0422 0.141 0.1804
Echinococcus granulosus single minded 2 0.0122 0.0355 0.0455
Schistosoma mansoni ran 0.0023 0.0009 0.0011
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0037 0.006 0.0059
Loa Loa (eye worm) serotonin transporter b 0.0225 0.0719 0.2123
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0081 0.0212 0.0211
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2874 1 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0014 0.0018
Entamoeba histolytica hypothetical protein 0.0039 0.0066 0.0639
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0209 0.0661 0.2458
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0214 0.0681 0.0871
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0017
Echinococcus multilocularis neuropeptide receptor 0.0063 0.0149 0.0191
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0041 0.0075 0.0138
Schistosoma mansoni jumonji/arid domain-containing protein 0.01 0.0279 0.0357
Onchocerca volvulus 0.0063 0.0149 0.0587
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0209 0.0661 0.6464
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0006 0.0017
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0041 0.0075 0.0095
Brugia malayi Calcitonin receptor-like protein seb-1 0.0161 0.0493 0.1456
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Giardia lamblia Hypothetical protein 0.002 0.0001 0.0004
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0109 0.031 0.0309
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0006 0.0007
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0031 0.004 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0286 0.1061
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Brugia malayi Dopamine receptor protein 1 0.0063 0.0149 0.0441
Onchocerca volvulus 0.0071 0.018 0.0707
Plasmodium vivax ferrodoxin reductase, putative 0.0209 0.0661 0.1948
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0006 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0023 0.0082
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0331 0.033
Leishmania major hypothetical protein, conserved 0.0037 0.006 0.0059
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0072 0.0183 0.0523
Brugia malayi Carboxylesterase family protein 0.0071 0.018 0.053
Plasmodium vivax multidomain scavenger receptor, putative 0.0125 0.0368 0.1084
Schistosoma mansoni inositol monophosphatase 0.0081 0.0212 0.0272
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0063 0.0149 0.0191
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0312 0.1021 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0006 0.0017
Brugia malayi 6-phosphofructokinase 0.0115 0.0332 0.098
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.002 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0006 0.0017
Brugia malayi Dehydrogenases, short chain protein 30 0.002 0.0001 0.0003
Brugia malayi G-protein coupled receptor 0.0063 0.0149 0.0441
Echinococcus granulosus tar DNA binding protein 0.0069 0.017 0.0218
Brugia malayi Cytochrome P450 family protein 0.0045 0.0087 0.0256
Leishmania major importin beta-1 subunit, putative 0.0025 0.0017 0.0016
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0038 0.0113
Schistosoma mansoni lipoxygenase 0.0256 0.0828 0.106
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0021 0.002
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0109 0.031 0.0309
Loa Loa (eye worm) neuropeptide F receptor 0.0063 0.0149 0.0441
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0184 0.0573 0.0572
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0063 0.0149 0.0191
Schistosoma mansoni hypothetical protein 0.0125 0.0368 0.0471
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0117 0.0347
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0069 0.017 0.0218
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0076 0.0278
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.0103 0.0102
Plasmodium falciparum LCCL domain-containing protein 0.0125 0.0368 0.1086
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Loa Loa (eye worm) latrophilin receptor protein 2 0.0051 0.0108 0.0318
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Echinococcus granulosus cytochrome P450 2K1 0.0035 0.0052 0.0066
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.0619 0.2302
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0154 0.057
Leishmania major trypanothione reductase 0.0986 0.3386 0.3385
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0063 0.0149 0.0191
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0035 0.0052 0.0146
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0063 0.0149 0.0191
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0109 0.031 0.0916
Schistosoma mansoni biogenic amine (5HT) receptor 0.0315 0.1035 0.1325
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0006 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0006 0.0017
Trypanosoma brucei hypothetical protein, conserved 0.0209 0.0661 0.066
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0063 0.0149 0.0191
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0074 0.0288
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0063 0.0149 0.0191
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0067
Echinococcus multilocularis neuropeptide receptor A26 0.0063 0.0149 0.0191
Brugia malayi neuropeptide F receptor 0.0063 0.0149 0.0441
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Echinococcus multilocularis RUN 0.0125 0.0368 0.0471
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0081 0.0212 0.0788
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0108 0.0397
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0021 0.002
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0002 0.0002
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.0063 0.0081
Mycobacterium tuberculosis Probable oxidoreductase 0.1012 0.3477 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0006 0.0007
Giardia lamblia PHD finger protein 15 0.0031 0.0038 0.0143
Loa Loa (eye worm) hypothetical protein 0.0335 0.1102 0.3254
Echinococcus multilocularis neuropeptide receptor 0.0063 0.0149 0.0191
Leishmania major calcium channel protein, putative,ion transporter, putative 0.013 0.0385 0.0384
Echinococcus granulosus sodium channel protein 0.013 0.0385 0.0493
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Echinococcus multilocularis para nitrobenzyl esterase 0.0071 0.018 0.023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0209 0.0661 0.2458
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0003
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0066 0.0085
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0085 0.0312
Trichomonas vaginalis glutamate synthase, putative 0.0209 0.0661 0.2458
Brugia malayi jmjC domain containing protein 0.01 0.0279 0.0823
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.0076 0.0215
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0035 0.0052 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0023 0.0082
Schistosoma mansoni glutamate synthase 0.0209 0.0661 0.0846
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0081 0.0104
Echinococcus granulosus peregrin 0.0031 0.0038 0.0049
Schistosoma mansoni hypothetical protein 0.0063 0.0149 0.0191
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0087 0.0085
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0023 0.0011 0.0031
Echinococcus granulosus tm gpcr rhodopsin 0.0063 0.0149 0.0191
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0154 0.044
Onchocerca volvulus 0.0059 0.0136 0.0535
Loa Loa (eye worm) hypothetical protein 0.0071 0.018 0.053
Plasmodium falciparum amino acid transporter, putative 0.0038 0.0063 0.0187
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0009 0.0026
Brugia malayi hypothetical protein 0.0063 0.0149 0.0441
Brugia malayi larval opioid receptor 0.0063 0.0149 0.0441
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0209 0.0661 0.6464
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0029 0.0037
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0006 0.0018
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0184 0.0573 0.2133
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Schistosoma mansoni microtubule-associated protein tau 0.2249 0.7812 1
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0209 0.0661 0.066
Schistosoma mansoni retinal dehydrogenase 0.002 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0058 0.0214
Echinococcus multilocularis conserved hypothetical protein 0.002 0.0001 0.0001
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0021 0.002
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0009 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0067 0.0247
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0006 0.0017
Loa Loa (eye worm) hypothetical protein 0.0058 0.0132 0.0391
Trichomonas vaginalis DNA helicase recq, putative 0.0049 0.01 0.037
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0033 0.0119
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.004 0.0117
Onchocerca volvulus 0.0038 0.0063 0.0247
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0583 0.217
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Echinococcus multilocularis thioredoxin glutathione reductase 0.0986 0.3386 0.4335
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0187 0.0693
Echinococcus granulosus jun protein 0.0271 0.0879 0.1125
Brugia malayi hypothetical protein 0.0063 0.0149 0.0441
Echinococcus multilocularis dna polymerase eta 0.0048 0.0097 0.0124
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2107 0.7313 0.7313
Echinococcus multilocularis bloom syndrome protein 0.0049 0.01 0.0128
Leishmania major acetoin dehydrogenase e3 component-like protein 0.2107 0.7313 0.7313
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0041 0.0075 0.0095
Echinococcus multilocularis jumonji domain containing 1A 0.0027 0.0023 0.0029
Brugia malayi Heterochromatin protein 1 0.0073 0.0187 0.0552
Echinococcus granulosus carboxylesterase 5A 0.0422 0.141 0.1804
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0209 0.0661 0.1951
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0038 0.0112
Loa Loa (eye worm) dehydrogenase 0.002 0.0001 0.0003
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0152 0.0463 0.1328
Brugia malayi Uncoordinated protein 44 0.0031 0.004 0.0117
Onchocerca volvulus 0.0105 0.0299 0.1179
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0191 0.06 0.2234
Loa Loa (eye worm) hypothetical protein 0.0023 0.0011 0.0031
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0076 0.0278
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0035 0.0052 0.0146
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Echinococcus granulosus para nitrobenzyl esterase 0.0071 0.018 0.023
Onchocerca volvulus Netrin receptor homolog 0.0031 0.004 0.0153
Loa Loa (eye worm) hypothetical protein 0.0031 0.0037 0.011
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0038 0.0049
Schistosoma mansoni hypothetical protein 0.0035 0.0052 0.0066
Loa Loa (eye worm) acetylcholinesterase 1 0.0422 0.141 0.4163
Echinococcus granulosus G protein coupled receptor 139 0.0063 0.0149 0.0191
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0006 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0103 0.0304
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0003
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0035 0.0052 0.0189
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0109 0.031 0.0309
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0023 0.0067
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0038 0.0063 0.0187
Plasmodium falciparum importin beta, putative 0.0031 0.0037 0.011
Leishmania major mitochondrial DNA polymerase beta 0.031 0.1015 0.1014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2414 0.839 0.839
Brugia malayi hypothetical protein 0.002 0.0001 0.0003
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Loa Loa (eye worm) solute carrier family 6 member 4 0.0225 0.0719 0.2123
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0209 0.0661 0.0846
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0006 0.0007
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.0117 0.0347
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0063 0.0149 0.0441
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0035 0.0052 0.0146
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0082 0.0081
Echinococcus multilocularis g protein coupled receptor 0.0063 0.0149 0.0191
Echinococcus multilocularis orexin receptor type 2 0.0063 0.0149 0.0191
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0041 0.0075 0.0274
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0086
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.013 0.0385 0.0493
Brugia malayi Carboxylesterase family protein 0.0071 0.018 0.053
Schistosoma mansoni opsin-like receptor 0.0063 0.0149 0.0191
Schistosoma mansoni chromobox protein 0.0073 0.0187 0.0239
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0331 0.3236
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0209 0.0661 0.1948
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0286 0.1061
Schistosoma mansoni chromobox protein 0.0073 0.0187 0.0239
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0035 0.0052 0.0146
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0003
Onchocerca volvulus 0.0063 0.0149 0.0587
Loa Loa (eye worm) programmed cell death 8 0.0209 0.0661 0.1951
Echinococcus multilocularis lamin dm0 0.0059 0.0136 0.0174
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0209 0.0661 0.0846
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0286 0.1061
Brugia malayi putative neuropeptide receptor NPR1 0.0063 0.0149 0.0441
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1021 0.3803
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0071 0.018 0.023
Brugia malayi phosphofructokinase 0.0115 0.0331 0.0978
Leishmania major protein kinase, putative 0.0043 0.0079 0.0078
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0063 0.0149 0.0441
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0035 0.0052 0.0189
Echinococcus multilocularis glutamate synthase 0.0209 0.0661 0.0846
Echinococcus multilocularis voltage gated potassium channel 0.0023 0.0011 0.0013
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.017 0.1656
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0102 0.0286 0.0366
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.0117
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0331 0.3236
Brugia malayi Cytochrome P450 family protein 0.0057 0.0128 0.0377
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0006 0.0017
Echinococcus granulosus neuropeptides capa receptor 0.0063 0.0149 0.0191
Schistosoma mansoni hypothetical protein 0.0039 0.0066 0.0085
Echinococcus multilocularis serotonin transporter 0.0225 0.0719 0.092
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0583 0.217
Echinococcus granulosus orexin receptor type 2 0.0063 0.0149 0.0191
Echinococcus granulosus importin subunit beta 1 0.0031 0.0037 0.0048
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.000000000032112 0.000000000094834
Entamoeba histolytica hypothetical protein 0.0025 0.0017 0.0154
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0435 0.1454 0.4179
Schistosoma mansoni amine GPCR 0.0063 0.0149 0.0191
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0209 0.0661 0.2458
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0085 0.0312
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0149 0.0191
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0257 0.0329
Mycobacterium ulcerans carboxylesterase, LipT 0.0071 0.018 0.0665
Echinococcus multilocularis jun protein 0.0271 0.0879 0.1125
Brugia malayi nuclear hormone receptor 0.0022 0.0006 0.0017
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0006 0.0007
Brugia malayi hypothetical protein 0.0063 0.0149 0.0441
Loa Loa (eye worm) melatonin receptor type 1A 0.0063 0.0149 0.0441
Echinococcus granulosus voltage gated potassium channel 0.0023 0.0011 0.0013
Trichomonas vaginalis adenylate cyclase, putative 0.0041 0.0075 0.0274
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Schistosoma mansoni steroid dehydrogenase 0.002 0.0001 0.0001
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0063 0.0149 0.0191
Echinococcus multilocularis conserved hypothetical protein 0.076 0.2592 0.3318
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0209 0.0661 0.2458
Echinococcus multilocularis allatostatin A receptor 0.0063 0.0149 0.0191
Trichomonas vaginalis inositol monophosphatase, putative 0.0081 0.0212 0.0788
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0006 0.0007
Loa Loa (eye worm) carboxylesterase 0.0071 0.018 0.053
Schistosoma mansoni disulfide oxidoreductase 0.0209 0.0661 0.0846
Onchocerca volvulus 0.0213 0.0675 0.2668
Schistosoma mansoni hypothetical protein 0.0031 0.004 0.0051
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1012 0.3477 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0786 0.2684 1
Schistosoma mansoni hypothetical protein 0.0063 0.0149 0.0191
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0786 0.2684 1
Loa Loa (eye worm) doublecortin family protein 0.0125 0.0368 0.1086
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0006 0.0007
Schistosoma mansoni steroid dehydrogenase 0.002 0.0001 0.0001
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0052 0.011 0.0325
Echinococcus granulosus neuroligin 0.0071 0.018 0.023
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0187
Echinococcus multilocularis lysine specific demethylase 5A 0.01 0.0279 0.0357
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0331 0.0978
Echinococcus multilocularis lipoxygenase domain containing protein 0.0125 0.0368 0.0471
Brugia malayi AKH receptor 0.0063 0.0149 0.0441
Brugia malayi hypothetical protein 0.0213 0.0675 0.1993
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0069 0.0088
Schistosoma mansoni DNA polymerase eta 0.0048 0.0097 0.0124
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Trichomonas vaginalis apoptosis inducing factor, putative 0.0209 0.0661 0.2458
Echinococcus multilocularis dro:myosuppressin receptor 0.0063 0.0149 0.0191
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Echinococcus granulosus biogenic amine 5HT receptor 0.0063 0.0149 0.0191
Schistosoma mansoni biogenic amine receptor 0.0063 0.0149 0.0191
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0038 0.0063 0.0081
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.017 0.0502
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0209 0.0661 0.2458
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0331 0.033
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0209 0.0661 0.1951
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0041 0.0075 0.0274
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0209 0.0661 0.1897
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0209 0.0661 0.1951
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0037 0.006 0.0077
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0081 0.0212 0.2072
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0047 0.0139
Loa Loa (eye worm) hypothetical protein 0.0519 0.1747 0.5159
Brugia malayi neuropeptide F receptor 0.0063 0.0149 0.0441
Echinococcus multilocularis chromobox protein 1 0.0073 0.0187 0.0239
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.2414 0.839 0.839
Toxoplasma gondii exonuclease III APE 0.0042 0.0076 0.0224
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0035 0.0052 0.0146
Schistosoma mansoni kinase 0.0052 0.0112 0.0144
Brugia malayi Death domain containing protein 0.0031 0.004 0.0117
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0049 0.0103 0.0102
Echinococcus granulosus chromobox protein 1 0.0073 0.0187 0.0239
Brugia malayi hypothetical protein 0.0063 0.0149 0.0441
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0035 0.0052 0.0189
Loa Loa (eye worm) RecQ helicase 0.0049 0.01 0.0296
Trichomonas vaginalis glutamate synthase, putative 0.0209 0.0661 0.2458
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0209 0.0661 0.1897
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0035 0.0052 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0023 0.0082
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0109 0.031 0.0309
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0017 0.0059
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0072 0.0183 0.0523
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0103 0.0304
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0002 0.0005
Brugia malayi PHD-finger family protein 0.0031 0.0038 0.0113
Echinococcus granulosus g protein coupled receptor 0.0063 0.0149 0.0191
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0061 0.0222
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0035 0.0052 0.0146
Schistosoma mansoni jumonji/arid domain-containing protein 0.01 0.0279 0.0357
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Brugia malayi Dopamine receptor 0.0063 0.0149 0.0441
Onchocerca volvulus Alhambra homolog 0.0031 0.0038 0.0148
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.01 0.0296
Loa Loa (eye worm) hypothetical protein 0.0041 0.0074 0.0218
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0002 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1021 0.3803
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0038 0.0112
Brugia malayi Protein kinase domain containing protein 0.0033 0.0044 0.0131
Trypanosoma brucei C-8 sterol isomerase, putative 0.0405 0.135 0.1349
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0027 0.0023 0.0067
Echinococcus multilocularis neuropeptide s receptor 0.0063 0.0149 0.0191
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0583 0.217
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.0076 0.0075
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0063 0.0149 0.0191
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0093 0.0257 0.0329
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0786 0.2684 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.017 0.0169
Brugia malayi serine/threonine-protein kinase plk-2 0.0102 0.0286 0.0844
Loa Loa (eye worm) hypothetical protein 0.0422 0.141 0.4163
Brugia malayi Dehydrogenases, short chain protein 2 0.002 0.0001 0.0003
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0209 0.0661 0.2458
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.004 0.0117
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0071 0.018 0.023
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.0076 0.0224
Trypanosoma brucei mitochondrial DNA polymerase beta 0.031 0.1015 0.1014
Onchocerca volvulus 0.0063 0.0149 0.0587
Schistosoma mansoni neuropeptide receptor 0.0063 0.0149 0.0191
Entamoeba histolytica Ran family GTPase 0.0023 0.0009 0.0075
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0049 0.0103 0.0102
Loa Loa (eye worm) hypothetical protein 0.0209 0.0661 0.1951
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0051 0.0108 0.0138
Schistosoma mansoni ap endonuclease 0.0042 0.0076 0.0097
Trichomonas vaginalis mercuric reductase, putative 0.0786 0.2684 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0063 0.0149 0.0191
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.031 0.1152
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0289 0.0853
Leishmania major cytochrome p450-like protein 0.0045 0.0087 0.0085
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0003
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0443 0.0442
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0027 0.0023 0.0022
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0063 0.0149 0.0441
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.0063 0.0187
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0049 0.0103 0.0998
Schistosoma mansoni tar DNA-binding protein 0.0069 0.017 0.0218
Plasmodium vivax importin-beta 2, putative 0.0031 0.0037 0.0107
Leishmania major GTP-binding protein, putative 0.0023 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0003
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0006 0.0007
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0786 0.2684 0.3435
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0063 0.0184
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Brugia malayi Carboxylesterase family protein 0.0422 0.141 0.4163
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0006 0.0017
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.017 0.0169
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0063 0.0149 0.0441
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0039 0.0068 0.0066
Onchocerca volvulus 0.0063 0.0149 0.0587
Schistosoma mansoni voltage-gated potassium channel 0.0055 0.0123 0.0158
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0063 0.0149 0.0191
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0209 0.0661 0.1897
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0187
Schistosoma mansoni biogenic amine receptor 0.0063 0.0149 0.0191
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0006 0.0017
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0786 0.2684 0.7925
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0027 0.0023 0.0029
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0149 0.0191
Giardia lamblia Fructose-bisphosphate aldolase 0.0312 0.1021 0.3805
Schistosoma mansoni neuropeptide receptor 0.0063 0.0149 0.0191
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0154 0.0456
Brugia malayi jmjC domain containing protein 0.0027 0.0023 0.0067
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0209 0.0661 0.2461
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.002 0.0001 0.0003
Echinococcus granulosus WW domain containing oxidoreductase 0.002 0.0001 0.0001
Echinococcus granulosus allatostatin A receptor 0.0063 0.0149 0.0191
Giardia lamblia Kinase, PLK 0.0102 0.0286 0.1065
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0063 0.0149 0.0191
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0035 0.0052 0.0189
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0035 0.0052 0.0146
Giardia lamblia DINP protein human, muc B family 0.0021 0.0002 0.0006
Brugia malayi Dopamine receptor protein 2 0.0063 0.0149 0.0441
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0926 0.3448
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0786 0.2684 0.2683
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.0076 0.0282
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0209 0.0661 0.1951
Loa Loa (eye worm) oxidoreductase 0.002 0.0001 0.0003
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.1015 0.1014
Chlamydia trachomatis thioredoxin reductase 0.0209 0.0661 0.2353
Leishmania major NADH dehydrogenase, putative 0.0209 0.0661 0.066
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0786 0.2684 0.7925
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Trichomonas vaginalis glutathione reductase, putative 0.0786 0.2684 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0191 0.06 0.1724
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0023 0.0067
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0376 0.1248 0.1597
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0117 0.0116
Brugia malayi Thioredoxin reductase 0.0986 0.3386 1
Echinococcus multilocularis inositol monophosphatase 1 0.0081 0.0212 0.0272
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0063 0.0149 0.0191
Brugia malayi ImpB/MucB/SamB family protein 0.0048 0.0097 0.0286
Toxoplasma gondii oxidoreductase, putative 0.002 0.0001 0.0003
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0041 0.0075 0.0274
Echinococcus granulosus inositol monophosphatase 1 0.0081 0.0212 0.0272
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0926 0.3448
Echinococcus granulosus microtubule associated protein 2 0.2249 0.7812 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0002 0.0002
Loa Loa (eye worm) carboxylesterase 0.0422 0.141 0.4163
Echinococcus multilocularis fmrfamide receptor 0.0063 0.0149 0.0191
Onchocerca volvulus 0.0071 0.018 0.0707
Schistosoma mansoni rab6-interacting 0.0125 0.0368 0.0471
Echinococcus granulosus somatostatin receptor 0.0063 0.0149 0.0191
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0161 0.0494 0.0632
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0023 0.0011 0.0013
Echinococcus granulosus hypothetical protein 0.0823 0.2812 0.36
Echinococcus multilocularis aryl hydrocarbon receptor 0.0041 0.0075 0.0095
Mycobacterium tuberculosis Probable reductase 0.0435 0.1454 0.4179
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0063 0.0149 0.0191
Toxoplasma gondii NADPH-glutathione reductase 0.0786 0.2684 0.7925
Echinococcus granulosus mitogen activated protein kinase 3 0.0109 0.031 0.0397
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0006 0.0007
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0271 0.0879 0.1125
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0006 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Schistosoma mansoni tar DNA-binding protein 0.0069 0.017 0.0218
Echinococcus granulosus glutamate synthase 0.0209 0.0661 0.0846
Echinococcus granulosus neuropeptide receptor A26 0.0063 0.0149 0.0191
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.0076 0.0075
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.0331 0.0424
Brugia malayi jmjC domain containing protein 0.0027 0.0023 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0058 0.0214
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0052 0.011 0.0141
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.0138
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0052 0.011 0.0141
Loa Loa (eye worm) phosphofructokinase 0.0115 0.0331 0.0978
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0102 0.0286 0.0285
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.1015 0.1014
Loa Loa (eye worm) RNA binding protein 0.0069 0.017 0.0503
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0006 0.0017
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0926 0.3448
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0061 0.0222
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0786 0.2684 0.2683
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0063 0.0149 0.0191
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0038 0.0362
Echinococcus granulosus g-protein coupled receptor 0.0063 0.0149 0.0191
Schistosoma mansoni rab6-interacting 0.0125 0.0368 0.0471
Echinococcus granulosus fmrfamide receptor 0.0063 0.0149 0.0191
Loa Loa (eye worm) hypothetical protein 0.0405 0.135 0.3988
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0063 0.0149 0.0587
Brugia malayi RNA recognition motif domain containing protein 0.0069 0.017 0.0503
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0049 0.0103 0.0102
Loa Loa (eye worm) hypothetical protein 0.0125 0.0368 0.1086
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0209 0.0661 0.2458
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0187
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0038 0.0063 0.0187
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0006 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0035 0.0052 0.0146
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0191 0.06 0.0768
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0006 0.0018
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0331 0.1231
Onchocerca volvulus Neuropeptide F receptor homolog 0.0063 0.0149 0.0587
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.017 0.0169
Brugia malayi hypothetical protein 0.0502 0.169 0.4992
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0154 0.057
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.0926 0.3448
Onchocerca volvulus 0.0038 0.0063 0.0247
Echinococcus granulosus GPCR family 2 0.0051 0.0108 0.0138
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0786 0.2684 0.2683
Brugia malayi steroid hormone receptor 0.0022 0.0006 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.031 0.1152
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0032 0.0114
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0002 0.0001
Brugia malayi hypothetical protein 0.0128 0.0379 0.112
Onchocerca volvulus 0.0041 0.0075 0.0291
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0038 0.0049
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0001 0.0003
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1012 0.3477 1
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.004 0.0119
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.002 0.0001 0.0001
Schistosoma mansoni jumonji domain containing protein 0.0143 0.043 0.0551
Brugia malayi Carboxylesterase family protein 0.0071 0.018 0.053
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.01 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0006 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0149 0.0191
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0001 0.0001
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0081 0.0212 0.0788
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0063 0.0149 0.0191
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0038 0.0138
Toxoplasma gondii Erv1 / Alr family protein 0.0037 0.006 0.0177
Echinococcus multilocularis g-protein coupled receptor 0.0063 0.0149 0.0191
Echinococcus granulosus dna polymerase eta 0.0048 0.0097 0.0124
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.006 0.0177
Echinococcus granulosus tm gpcr rhodopsin 0.0063 0.0149 0.0191
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0002 0.0002
Loa Loa (eye worm) cytochrome P450 0.0035 0.0052 0.0153
Schistosoma mansoni hypothetical protein 0.0102 0.0289 0.037
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0786 0.2684 0.7925
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Echinococcus granulosus neuropeptide receptor 0.0063 0.0149 0.0191
Leishmania major hypothetical protein, conserved 0.0054 0.0117 0.0116
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0038 0.0112
Trichomonas vaginalis set domain proteins, putative 0.0741 0.2526 0.9413
Brugia malayi bHLH-PAS transcription factor 0.0118 0.0343 0.1012
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0063 0.0149 0.0441
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0009 0.0023
Schistosoma mansoni hypothetical protein 0.0063 0.0149 0.0191
Brugia malayi hypothetical protein 0.0125 0.0368 0.1086
Schistosoma mansoni amine GPCR 0.061 0.2067 0.2645
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0063 0.0149 0.0441
Mycobacterium ulcerans putative regulatory protein 0.0118 0.0343 0.1273
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.0063 0.0187
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0006 0.0007
Schistosoma mansoni steroid dehydrogenase 0.002 0.0001 0.0001
Echinococcus multilocularis sodium and chloride dependent glycine 0.0038 0.0063 0.0081
Leishmania major DNA polymerase eta, putative 0.0034 0.0047 0.0046
Schistosoma mansoni carbonyl reductase 0.002 0.0001 0.0001
Giardia lamblia GTOR 0.0049 0.0103 0.0383
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.0331 0.1231
Schistosoma mansoni hypothetical protein 0.0051 0.0108 0.0138
Onchocerca volvulus Glucosylceramidase homolog 0.0187 0.0583 0.2305
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0006 0.0007
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.01 0.0296
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0049 0.0103 0.0102
Trichomonas vaginalis guanylate cyclase, putative 0.0041 0.0075 0.0274
Plasmodium falciparum glutathione reductase 0.0986 0.3386 1
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0286 0.1061
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0006 0.0007
Brugia malayi hypothetical protein 0.0071 0.018 0.053
Schistosoma mansoni ran 0.0023 0.0009 0.0011
Brugia malayi G-protein coupled receptor 0.0063 0.0149 0.0441
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0035 0.0052 0.0189
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.01 0.0128
Echinococcus granulosus geminin 0.0376 0.1248 0.1597
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.01 0.0128
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0039 0.0068 0.0066
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0209 0.0661 0.6464
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0209 0.0661 0.0846
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0001 0.0001
Onchocerca volvulus 0.0741 0.2527 1
Brugia malayi Bromodomain containing protein 0.0031 0.0038 0.0113
Echinococcus granulosus carbonyl reductase 1 0.002 0.0001 0.0001
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0001 0.0001
Schistosoma mansoni biogenic amine receptor 0.0063 0.0149 0.0191
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0002 0.0002
Brugia malayi putative neuropeptide receptor 0.0063 0.0149 0.0441
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Loa Loa (eye worm) carboxylesterase 0.0071 0.018 0.053
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0082 0.0081
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0063 0.0149 0.0191
Schistosoma mansoni BC026374 protein (S09 family) 0.0071 0.018 0.023
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0082 0.0081
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0063 0.0149 0.0191
Trypanosoma cruzi hypothetical protein, conserved 0.0209 0.0661 0.066
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0209 0.0661 0.0846
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0081 0.0212 0.0211
Echinococcus multilocularis BC026374 protein (S09 family) 0.0071 0.018 0.023
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0786 0.2684 0.2683
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0001 0.0001
Brugia malayi hypothetical protein 0.0161 0.0494 0.1459
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.002 0.0001 0.0003
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0071 0.018 0.053
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0041 0.0075 0.022
Leishmania major cytochrome p450-like protein 0.0035 0.0052 0.0051
Echinococcus granulosus sodium and chloride dependent glycine 0.0038 0.0063 0.0081
Brugia malayi hypothetical protein 0.0063 0.0149 0.0441
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.017 0.0169
Echinococcus multilocularis g protein coupled receptor 0.0063 0.0149 0.0191
Loa Loa (eye worm) hypothetical protein 0.0032 0.0043 0.0126
Loa Loa (eye worm) thioredoxin reductase 0.0986 0.3386 1
Schistosoma mansoni steroid dehydrogenase 0.002 0.0001 0.0001
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0422 0.141 0.1804
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0035 0.0052 0.0189
Echinococcus granulosus g protein coupled receptor 0.0063 0.0149 0.0191
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1012 0.3477 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0006 0.0017
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0087 0.0256
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0209 0.0661 0.2458
Echinococcus granulosus g protein coupled receptor 0.0063 0.0149 0.0191
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Loa Loa (eye worm) TYRA-2 protein 0.0063 0.0149 0.0441
Echinococcus granulosus tm gpcr rhodopsin 0.0975 0.3345 0.4282
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0063 0.0149 0.0191
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0049 0.0103 0.0998
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0435 0.1454 0.4179
Echinococcus granulosus rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Plasmodium vivax glutathione reductase, putative 0.0986 0.3386 1
Onchocerca volvulus 0.0063 0.0149 0.0587
Loa Loa (eye worm) TAR-binding protein 0.0069 0.017 0.0503
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0017
Leishmania major hypothetical protein, conserved 0.0209 0.0661 0.066
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0271
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0105 0.0299 0.0383
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0209 0.0661 0.0846
Schistosoma mansoni hypothetical protein 0.0024 0.0014 0.0018
Trypanosoma cruzi trypanothione reductase, putative 0.0786 0.2684 0.2683
Echinococcus multilocularis oxidoreductase 0.002 0.0001 0.0001
Echinococcus multilocularis sodium and chloride dependent glycine 0.0038 0.0063 0.0081
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0035 0.0052 0.0189
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Brugia malayi Pre-SET motif family protein 0.0093 0.0257 0.0758
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0209 0.0661 0.066
Plasmodium falciparum ferrodoxin reductase-like protein 0.0209 0.0661 0.1951
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0023 0.0022
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0986 0.3386 0.974
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0006 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0063 0.0149 0.0191
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0003
Echinococcus multilocularis survival motor neuron protein 1 0.0502 0.169 0.2164
Schistosoma mansoni hypothetical protein 0.011 0.0315 0.0403
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.002 0.0001 0.0003
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0051 0.0108 0.0138
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.0331 0.033
Echinococcus granulosus Polycystic kidney disease protein 0.0125 0.0368 0.0471
Brugia malayi 6-phosphofructokinase 0.0115 0.0331 0.0978
Brugia malayi Latrophilin receptor protein 2 0.0051 0.0108 0.0318
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0003
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.0063 0.0081
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0284 0.0926 0.2735
Echinococcus granulosus neuropeptide Y receptor 0.0063 0.0149 0.0191
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0043 0.008 0.0235
Brugia malayi hypothetical protein 0.0534 0.1802 0.5322
Schistosoma mansoni short chain dehydrogenase 0.002 0.0001 0.0001
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0001 0.0003
Onchocerca volvulus 0.0032 0.0043 0.0165
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0003
Giardia lamblia Short-chain dehydrogenase, putative 0.002 0.0001 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0023 0.0082
Echinococcus multilocularis neuropeptides capa receptor 0.0063 0.0149 0.0191
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0035 0.0052 0.0146
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0035 0.0052 0.0146
Brugia malayi jmjC domain containing protein 0.0164 0.0504 0.1487
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0125 0.0368 0.1086
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0071 0.018 0.0514
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0067 0.0247
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0191 0.06 0.0599
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0006 0.0007
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0006 0.0007
Echinococcus granulosus sex peptide receptor 0.0063 0.0149 0.0191
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0038 0.0063 0.0081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.01 0.0128
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0063 0.0149 0.0441
Loa Loa (eye worm) hypothetical protein 0.0071 0.018 0.053
Schistosoma mansoni netrin receptor unc5 0.0031 0.004 0.0051
Loa Loa (eye worm) hypothetical protein 0.0502 0.169 0.4992
Loa Loa (eye worm) hypothetical protein 0.0063 0.0149 0.0441
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0184 0.0573 0.0572
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0583 0.217
Echinococcus multilocularis phd:f box containing protein 0.0027 0.0023 0.0029
Echinococcus granulosus hypothetical protein 0.002 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0315 0.1035 0.3056
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0038 0.0063 0.0081
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0002 0.0002

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 6 nM Displacement of [125I]-IP-10 from CXCR3 receptor (unknown origin) expressed in human PBMC in RPMI-1640 buffer supplemented with 0.5% BSA ChEMBL. 18061451
IC50 (binding) = 6 nM Displacement of [125I]-IP-10 from CXCR3 receptor (unknown origin) expressed in human PBMC in RPMI-1640 buffer supplemented with 0.5% BSA ChEMBL. 18061451
IC50 (binding) = 35 nM Displacement of [125I]-IP-10 from CXCR3 receptor (unknown origin) expressed in human PBMC in EDTA-anti-coagulated human plasma ChEMBL. 18061451
IC50 (binding) = 35 nM Displacement of [125I]-IP-10 from CXCR3 receptor (unknown origin) expressed in human PBMC in EDTA-anti-coagulated human plasma ChEMBL. 18061451
IC50 (functional) = 521 nM Antagonist activity at CXCR3 (unknown origin) assessed as ITAC-mediated migration of human PBMC in presence of 100% human plasma ChEMBL. 18061451
IC50 (functional) = 521 nM Antagonist activity at CXCR3 (unknown origin) assessed as ITAC-mediated migration of human PBMC in presence of 100% human plasma ChEMBL. 18061451

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.