Detailed information for compound 506612

Basic information

Technical information
  • TDR Targets ID: 506612
  • Name: 4-cyano-N-[4-(4-methylpiperazin-1-yl)-2-(4-me thylpiperidin-1-yl)phenyl]-1H-pyrrole-2-carbo xamide
  • MW: 406.524 | Formula: C23H30N6O
  • H donors: 2 H acceptors: 2 LogP: 2.94 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1c[nH]c(c1)C(=O)Nc1ccc(cc1N1CCC(CC1)C)N1CCN(CC1)C
  • InChi: 1S/C23H30N6O/c1-17-5-7-29(8-6-17)22-14-19(28-11-9-27(2)10-12-28)3-4-20(22)26-23(30)21-13-18(15-24)16-25-21/h3-4,13-14,16-17,25H,5-12H2,1-2H3,(H,26,30)
  • InChiKey: DXPSQKSTVIVZLV-UHFFFAOYSA-N  

Network

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Synonyms

  • 4-cyano-N-[4-(4-methylpiperazin-1-yl)-2-(4-methyl-1-piperidyl)phenyl]-1H-pyrrole-2-carboxamide
  • 4-cyano-N-[4-(4-methyl-1-piperazinyl)-2-(4-methyl-1-piperidinyl)phenyl]-1H-pyrrole-2-carboxamide
  • 4-cyano-N-[4-(4-methylpiperazino)-2-(4-methylpiperidino)phenyl]-1H-pyrrole-2-carboxamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens fms-related tyrosine kinase 3 Starlite/ChEMBL References
Homo sapiens colony stimulating factor 1 receptor Starlite/ChEMBL References
Homo sapiens neurotrophic tyrosine kinase, receptor, type 1 Starlite/ChEMBL References
Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog Starlite/ChEMBL References
Homo sapiens AXL receptor tyrosine kinase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus macrophage colony stimulating factor 1 receptor Get druggable targets OG5_132967 All targets in OG5_132967
Schistosoma japonicum IPR008957,Fibronectin, type III-like fold,domain-containing Get druggable targets OG5_132328 All targets in OG5_132328

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0085
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0031 0.0032 0.003
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0058 0.011 0.011
Loa Loa (eye worm) 6-phosphofructokinase 0.0222 0.0575 0.1085
Loa Loa (eye worm) glutaminase 2 0.0267 0.0704 0.1328
Onchocerca volvulus 0.0464 0.1264 0.3168
Echinococcus multilocularis ATP binding cassette sub family G 0.0036 0.0046 0.0044
Echinococcus granulosus tachykinin peptides receptor 99D 0.0231 0.0601 0.06
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0084 0.0083
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0024 0.0012 0.0011
Echinococcus granulosus transient receptor potential cation channel 0.0031 0.0032 0.003
Treponema pallidum NADH oxidase 0.0956 0.2661 1
Mycobacterium ulcerans dehydrogenase 0.0254 0.0666 0.2502
Echinococcus granulosus biogenic amine 5HT receptor 0.0595 0.1634 0.1633
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0085 0.0186 0.0196
Plasmodium falciparum heterochromatin protein 1 0.0035 0.0045 0.0128
Schistosoma mansoni biogenic amine receptor 0.0231 0.0601 0.0609
Trichomonas vaginalis chromobox protein, putative 0.0066 0.0133 0.033
Mycobacterium ulcerans NADH dehydrogenase 0.0254 0.0666 0.2502
Echinococcus multilocularis chromobox protein 1 0.0094 0.0212 0.0211
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1471 0.4124 0.4386
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0075 0.0157 0.0589
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0024 0.0012 0.0011
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0254 0.0666 0.0664
Schistosoma mansoni single-minded 0.0147 0.0363 0.0367
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0336 0.0899 1
Loa Loa (eye worm) hypothetical protein 0.0536 0.1467 0.2768
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.004 0.0059 0.0061
Echinococcus granulosus chromobox protein 2 0.0035 0.0045 0.0044
Trypanosoma brucei PAB1-binding protein , putative 0.0101 0.0231 0.0244
Loa Loa (eye worm) carboxylesterase 0.0058 0.011 0.0207
Loa Loa (eye worm) hypothetical protein 0.1471 0.4124 0.778
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0026 0.0018 0.0017
Brugia malayi hypothetical protein 0.0265 0.0698 0.1199
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0121 0.0122
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0173 0.0437 0.0436
Trichomonas vaginalis phosphofructokinase, putative 0.0222 0.0575 0.144
Trichomonas vaginalis PIKK family atypical protein kinase 0.018 0.0455 0.1137
Echinococcus granulosus death domain containing protein 0.0042 0.0064 0.0062
Echinococcus multilocularis ferredoxin adrenodoxin 0.0022 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0648 0.1787 0.337
Mycobacterium leprae Conserved hypothetical protein 0.0024 0.0012 0.0037
Schistosoma mansoni hypothetical protein 0.0035 0.0045 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0075 0.0157 0.0459
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.2458 0.6927 0.7367
Leishmania major phosphatidylinositol 3-kinase, putative 0.006 0.0116 0.0122
Trypanosoma cruzi cytochrome P450, putative 0.0101 0.0232 0.0245
Echinococcus multilocularis sodium leak channel non selective protein 0.0031 0.0032 0.003
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0024 0.0012 0.0035
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.015 0.037 0.0699
Brugia malayi nuclear hormone receptor 0.0049 0.0084 0.0145
Mycobacterium ulcerans hypothetical protein 0.0024 0.0012 0.0044
Loa Loa (eye worm) voltage-dependent calcium channel 0.0031 0.0032 0.006
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0031 0.0032 0.003
Echinococcus granulosus potassium voltage gated channel protein 0.0031 0.0032 0.003
Brugia malayi Intermediate filament tail domain containing protein 0.0106 0.0247 0.0424
Echinococcus multilocularis chromobox protein 1 0.0094 0.0212 0.0211
Echinococcus granulosus jun protein 0.0338 0.0904 0.0903
Echinococcus multilocularis neuropeptide FF receptor 2 0.0231 0.0601 0.06
Echinococcus multilocularis mitogen activated protein kinase 0.0204 0.0524 0.0523
Brugia malayi glutamate synthase 0.0254 0.0666 0.1143
Schistosoma mansoni neuropeptide F-like receptor 0.0231 0.0601 0.0609
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0324 0.081
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0173 0.0437 0.0436
Loa Loa (eye worm) hypothetical protein 0.0057 0.0107 0.0203
Trypanosoma brucei hypothetical protein, conserved 0.0254 0.0666 0.0707
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0051 0.0091 0.0091
Loa Loa (eye worm) ryanodine receptor 0.0031 0.0032 0.006
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0595 0.1634 0.1633
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0031 0.0032 0.0031
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0078 0.0167 0.0166
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0015 0.0014
Loa Loa (eye worm) serotonin transporter b 0.0639 0.176 0.332
Loa Loa (eye worm) hypothetical protein 0.1195 0.3339 0.6299
Entamoeba histolytica ABC transporter, putative 0.0036 0.0046 0.0504
Echinococcus multilocularis neuropeptide receptor A26 0.1158 0.3234 0.3233
Loa Loa (eye worm) hypothetical protein 0.0108 0.0253 0.0477
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2458 0.6927 0.7367
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0476 0.0482
Echinococcus granulosus defective proboscis extension response 0.0051 0.0091 0.009
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.1221 0.3414 1
Brugia malayi G protein-coupled receptor 0.0231 0.0601 0.1032
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0046 0.0045
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0054 0.0099 0.0098
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0042 0.0065 0.0064
Toxoplasma gondii endonuclease IV APN 0.0074 0.0155 0.0451
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.006 0.0115 0.0428
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0254 0.0666 0.0707
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Leishmania major cyclic nucleotide-binding protein-like protein 0.0024 0.0012 0.0011
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0031 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0104 0.0241 0.0455
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0186 0.0472 0.1181
Echinococcus granulosus dro:myosuppressin receptor 0.0231 0.0601 0.06
Echinococcus granulosus cGMP dependent protein kinase 1 0.0025 0.0017 0.0016
Brugia malayi Nuclear hormone receptor E75 0.0023 0.001 0.0018
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0046 0.0079
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0078 0.0167 0.0166
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus multilocularis musashi 0.0106 0.0247 0.0246
Brugia malayi hypothetical protein 0.0058 0.011 0.0188
Echinococcus multilocularis Polycystic kidney disease protein 0.0159 0.0396 0.0394
Echinococcus multilocularis tyrosine protein kinase Srms 0.0043 0.0066 0.0065
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0049 0.0084 0.0084
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0124 0.0123
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0108 0.0253 0.0252
Onchocerca volvulus 0.0231 0.0601 0.1507
Loa Loa (eye worm) voltage-gated potassium channel 0.0031 0.0032 0.006
Brugia malayi hypothetical protein 0.1195 0.3339 0.5734
Loa Loa (eye worm) steroid hormone receptor 0.0049 0.0084 0.0159
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0241 0.0629 0.0628
Echinococcus granulosus lamin dm0 0.0106 0.0247 0.0246
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0254 0.0666 0.2059
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0038 0.0053 0.0131
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0121 0.012
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0024 0.0012 0.0031
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0034 0.0041 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.0524 0.0531
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Trichomonas vaginalis adenylate cyclase, putative 0.0038 0.0053 0.0131
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Mycobacterium ulcerans hypothetical protein 0.0254 0.0666 0.2502
Onchocerca volvulus 0.0231 0.0601 0.1507
Brugia malayi hypothetical protein 0.0464 0.1264 0.2171
Schistosoma mansoni polycystin 1-related 0.0159 0.0396 0.04
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0231 0.0601 0.0609
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0049 0.0084 0.0159
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0108 0.0253 0.0255
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0455 0.1238 0.3627
Brugia malayi ecdysone receptor 0.0023 0.001 0.0018
Trichomonas vaginalis mercuric reductase, putative 0.0956 0.2661 0.6669
Trichomonas vaginalis hypothetical protein 0.0035 0.0045 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143 0.035 0.0876
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.018 0.0456 0.1332
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0068 0.0138 0.0136
Echinococcus granulosus neuropeptide Y receptor 0.0231 0.0601 0.06
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0049 0.0084 0.0145
Echinococcus multilocularis acetylcholinesterase 0.0344 0.0921 0.092
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0956 0.2661 0.2829
Brugia malayi Bromodomain containing protein 0.0039 0.0057 0.0098
Brugia malayi CHD4 protein 0.0039 0.0055 0.0094
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0075 0.0157 0.0165
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0226 0.0587 0.1719
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143 0.035 0.0876
Leishmania major protein kinase, putative 0.0064 0.0126 0.0132
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0155 0.0451
Loa Loa (eye worm) acetylcholinesterase 1 0.0344 0.0921 0.1738
Toxoplasma gondii phosphofructokinase PFKII 0.006 0.0115 0.0334
Toxoplasma gondii 6-phosphofructokinase 0.006 0.0115 0.0334
Echinococcus multilocularis neuropeptides capa receptor 0.0231 0.0601 0.06
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0254 0.0666 0.2498
Brugia malayi Dopamine receptor protein 2 0.0231 0.0601 0.1032
Loa Loa (eye worm) hypothetical protein 0.0108 0.0253 0.0477
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0207
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0075 0.0157 0.0459
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0085 0.0187 0.0186
Brugia malayi G-protein coupled receptor 0.0231 0.0601 0.1032
Leishmania major cytochrome p450-like protein 0.0075 0.0157 0.0165
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0186 0.0472 0.1772
Schistosoma mansoni voltage-dependent calcium channel 0.0031 0.0032 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0049 0.0084 0.0145
Trichomonas vaginalis glucosylceramidase, putative 0.0505 0.1379 0.3456
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0434
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0043 0.0066 0.0065
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0072 0.007
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0132 0.0318 0.0337
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0038 0.0053 0.0101
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0085 0.0187 0.0186
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0254 0.0666 0.2498
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0045 0.0109
Trichomonas vaginalis set domain proteins, putative 0.1424 0.3989 1
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0084 0.0084
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0031 0.0032 0.003
Schistosoma mansoni ankyrin 23/unc44 0.0042 0.0064 0.0063
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0034 0.0041 0.0071
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.018 0.0455 0.0482
Brugia malayi RNA binding protein 0.0062 0.0121 0.0208
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0046 0.0113
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0085
Echinococcus granulosus hyperpolarization activated cyclic 0.0054 0.0099 0.0098
Brugia malayi Serotonin receptor 0.207 0.5823 1
Schistosoma mansoni hypothetical protein 0.0085 0.0187 0.0189
Loa Loa (eye worm) hypothetical protein 0.0057 0.0107 0.0203
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0024 0.0012 0.004
Plasmodium vivax heterochromatin protein 1, putative 0.0035 0.0045 0.0128
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0075 0.0157 0.0589
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0155 0.0451
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0078 0.0167 0.0287
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.012 0.0347
Echinococcus multilocularis acetylcholinesterase 0.0344 0.0921 0.092
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0045 0.0109
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0085 0.0187 0.0186
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0108 0.0407
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0956 0.2661 0.4569
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0031 0.0032 0.0031
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0024 0.0012 0.0011
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0031 0.0032 0.0079
Schistosoma mansoni sodium-dependent amino acid transporter 0.0108 0.0253 0.0255
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0231 0.0601 0.06
Brugia malayi hypothetical protein 0.0031 0.0032 0.0054
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0455 0.1238 0.3627
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0084 0.0145
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0166 0.0417 0.129
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0207
Giardia lamblia DNA topoisomerase II 0.0074 0.0156 0.0583
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0024 0.0012 0.002
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0231 0.0601 0.1032
Schistosoma mansoni myosin xvIII 0.0231 0.0601 0.0609
Brugia malayi ion channel NompC 0.0031 0.0032 0.0054
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0254 0.0666 0.195
Echinococcus multilocularis thyroid hormone receptor alpha 0.0049 0.0084 0.0083
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.006 0.0116 0.0122
Echinococcus multilocularis serotonin transporter 0.0639 0.176 0.1759
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0524 0.1312
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0035
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0075 0.0157 0.0589
Echinococcus multilocularis lipoxygenase domain containing protein 0.0159 0.0396 0.0394
Plasmodium falciparum LCCL domain-containing protein 0.0159 0.0396 0.1155
Schistosoma mansoni cellular tumor antigen P53 0.015 0.037 0.0375
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0046 0.0169
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0054 0.0099 0.0098
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0186 0.0472 0.0501
Echinococcus multilocularis Immunoglobulin 0.0051 0.0091 0.009
Loa Loa (eye worm) hypothetical protein 0.015 0.037 0.0698
Chlamydia trachomatis ferredoxin 0.0022 0.0006 0.0017
Brugia malayi orphan nuclear receptor NR2E1 0.0023 0.001 0.0018
Brugia malayi hypothetical protein 0.0108 0.0253 0.0434
Loa Loa (eye worm) blistered cuticle protein 3 0.0146 0.036 0.068
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0338 0.0904 0.0903
Loa Loa (eye worm) cytochrome P450 0.0075 0.0157 0.0295
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0108 0.0253 0.0434
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0187 0.0476 0.0474
Trypanosoma brucei cAMP binding protein, putative 0.0024 0.0012 0.0011
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0254 0.0666 0.0707
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0231 0.0601 0.06
Echinococcus granulosus Polycystic kidney disease protein 0.0159 0.0396 0.0394
Leishmania major cytochrome p450-like protein 0.0075 0.0157 0.0165
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0254 0.0666 0.1947
Echinococcus multilocularis voltage dependent calcium channel 0.0031 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0231 0.0601 0.1134
Leishmania major phosphatidylinositol 3-related kinase, putative 0.006 0.0116 0.0122
Brugia malayi Tachykinin-like peptides receptor 99D 0.0231 0.0601 0.1032
Echinococcus granulosus transient receptor potential cation channel 0.0031 0.0032 0.003
Treponema pallidum hypothetical protein 0.009 0.0199 0.0748
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0254 0.0666 0.0664
Brugia malayi nuclear receptor RXR 0.0026 0.0018 0.0032
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0254 0.0666 0.195
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0035
Toxoplasma gondii cytochrome p450 superfamily protein 0.0075 0.0157 0.0455
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.018 0.0455 0.0482
Echinococcus granulosus sodium and chloride dependent glycine 0.0108 0.0253 0.0252
Entamoeba histolytica protein kinase, putative 0.0039 0.0055 0.0607
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0956 0.2661 0.7793
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0106 0.0247 0.0466
Echinococcus granulosus lamin 0.0106 0.0247 0.0246
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0316 0.0841 0.2464
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.018 0.0455 0.0482
Loa Loa (eye worm) hypothetical protein 0.004 0.0057 0.0108
Toxoplasma gondii selenide, water dikinase 0.0254 0.0666 0.1947
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0037 0.0049 0.0051
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0254 0.0666 0.195
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Loa Loa (eye worm) TYRA-2 protein 0.0231 0.0601 0.1134
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0037 0.0049 0.0048
Trichomonas vaginalis glucosylceramidase, putative 0.077 0.2131 0.5341
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Mycobacterium ulcerans hypothetical protein 0.0024 0.0012 0.0044
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Plasmodium falciparum glutathione reductase 0.0956 0.2661 0.7793
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0026 0.0018 0.0017
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0078 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0324 0.081
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0022 0.0006 0.0005
Schistosoma mansoni amine GPCR 0.1886 0.5301 0.5381
Echinococcus multilocularis tyrosine protein kinase Blk 0.0043 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0124 0.0308
Echinococcus granulosus neuropeptides capa receptor 0.0231 0.0601 0.06
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0035 0.0045 0.0044
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0254 0.0666 0.1666
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0116 0.0287
Toxoplasma gondii Erv1 / Alr family protein 0.007 0.0142 0.0414
Schistosoma mansoni transient receptor potential channel 0.0031 0.0032 0.0031
Echinococcus multilocularis geminin 0.0855 0.2373 0.2373
Brugia malayi cytoplasmic intermediate filament protein 0.0057 0.0107 0.0183
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0231 0.0601 0.06
Echinococcus multilocularis netrin receptor unc 5 0.005 0.0087 0.0086
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0031 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0035
Trichomonas vaginalis chromobox protein, putative 0.0094 0.0212 0.0529
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0046 0.0045
Echinococcus granulosus lipoxygenase domain containing protein 0.0159 0.0396 0.0394
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0108 0.0253 0.0252
Onchocerca volvulus 0.0159 0.0396 0.0991
Trichomonas vaginalis phosphofructokinase, putative 0.0222 0.0575 0.144
Treponema pallidum oxidoreductase 0.0254 0.0666 0.25
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0115 0.0285
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0026 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0062
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0301 0.0801 0.891
Echinococcus multilocularis transfer RNA-Gly 0.0031 0.0032 0.003
Echinococcus multilocularis g-protein coupled receptor 0.0231 0.0601 0.06
Echinococcus granulosus tyrosine protein kinase Src64B 0.0046 0.0077 0.0076
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.001 0.0009
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0054 0.0099 0.0186
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0049 0.0084 0.0083
Leishmania major ferric reductase, putative 0.0069 0.014 0.0147
Echinococcus granulosus peptide allatostatin:somatostatin 0.0231 0.0601 0.06
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0108 0.0253 0.0255
Echinococcus multilocularis serine protein kinase ATM 0.0034 0.0041 0.004
Plasmodium vivax 6-phosphofructokinase, putative 0.006 0.0115 0.0334
Echinococcus granulosus g-protein coupled receptor 0.0231 0.0601 0.06
Echinococcus granulosus FTZ F1 alpha 0.0049 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Trichomonas vaginalis PIKK family atypical protein kinase 0.018 0.0455 0.1137
Onchocerca volvulus 0.0024 0.0012 0.003
Loa Loa (eye worm) hypothetical protein 0.0222 0.0576 0.1086
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0054 0.0099 0.0098
Schistosoma mansoni nuclear receptor nhr-48 0.0023 0.001 0.0009
Echinococcus multilocularis Chromo domain 0.0035 0.0045 0.0044
Brugia malayi Death domain containing protein 0.0042 0.0064 0.0109
Leishmania major protein kinase, putative 0.0025 0.0017 0.0017
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0031 0.0032 0.003
Brugia malayi Immunoglobulin I-set domain containing protein 0.005 0.0087 0.015
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0132 0.0318 0.3539
Schistosoma mansoni voltage-gated potassium channel 0.0054 0.0099 0.0099
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0455 0.1238 0.3829
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0046 0.0046
Loa Loa (eye worm) intermediate filament protein 0.0106 0.0247 0.0466
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0046 0.0509
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0031 0.0032 0.0054
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0024 0.0012 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0116 0.0287
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0023 0.001 0.0009
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.006 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0494 0.1347 0.2541
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2458 0.6927 0.7367
Trypanosoma cruzi cAMP binding protein, putative 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.0038
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0075 0.0157 0.0589
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.018 0.0456 0.0455
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0254 0.0666 0.2059
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0024 0.0012 0.0027
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0015 0.0014
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0316 0.0841 0.3162
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0024 0.0012 0.0011
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0254 0.0666 0.1947
Toxoplasma gondii hypothetical protein 0.0031 0.0032 0.0089
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0022 0.0006 0.0022
Leishmania major DNA topoisomerase ii 0.0078 0.0167 0.0177
Brugia malayi larval opioid receptor 0.0231 0.0601 0.1032
Echinococcus multilocularis jun protein 0.0338 0.0904 0.0903
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0026 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0108 0.0253 0.0946
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0231 0.0601 0.0609
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Echinococcus multilocularis ATP binding cassette sub family G 0.0036 0.0046 0.0044
Toxoplasma gondii FATC domain-containing protein 0.0034 0.0041 0.0117
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0108 0.0253 0.0252
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0231 0.0601 0.06
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0031 0.0032 0.003
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0046 0.0045
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.333 0.9402 1
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0022 0.0006 0.0017
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0231 0.0601 0.0609
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.022 0.0548
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.006 0.0114 0.012
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0108 0.0253 0.0255
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0702 0.194 0.3331
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0049 0.0084 0.0083
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0231 0.0601 0.06
Schistosoma mansoni hypothetical protein 0.0075 0.0157 0.0158
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0956 0.2661 1
Onchocerca volvulus 0.0231 0.0601 0.1507
Leishmania major mitochondrial DNA topoisomerase II 0.006 0.0114 0.012
Echinococcus granulosus serotonin transporter 0.0639 0.176 0.1759
Loa Loa (eye worm) hypothetical protein 0.006 0.0114 0.0216
Onchocerca volvulus 0.0108 0.0253 0.0634
Trichomonas vaginalis glutathione reductase, putative 0.0956 0.2661 0.6669
Leishmania major protein kinase A regulatory subunit, putative 0.0024 0.0012 0.0011
Echinococcus multilocularis voltage dependent calcium channel 0.0031 0.0032 0.003
Schistosoma mansoni hypothetical protein 0.0395 0.1067 0.1082
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0254 0.0666 0.1143
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0077 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0058 0.011 0.0321
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0031 0.0032 0.0054
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0049 0.0084 0.0083
Schistosoma mansoni transient receptor potential channel 4 0.0031 0.0032 0.0031
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0254 0.0666 0.7406
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0143 0.0351 0.0372
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0026 0.0019 0.0018
Brugia malayi hypothetical protein 0.0026 0.0018 0.0032
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0022 0.0006 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0046 0.0113
Echinococcus granulosus serine protein kinase ATM 0.0034 0.0041 0.004
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0956 0.2661 0.266
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0039 0.0055 0.0054
Echinococcus granulosus allatostatin A receptor 0.0231 0.0601 0.06
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0254 0.0666 0.0664
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0108 0.0253 0.0252
Echinococcus multilocularis 0.0075 0.0157 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0024 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0012 0.0027
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0046 0.0077 0.0076
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0022 0.0006 0.0005
Loa Loa (eye worm) CHromoDomain protein family member 0.0039 0.0055 0.0104
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.007 0.0142 0.0141
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0204 0.0524 0.0556
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0001 0.0002
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0254 0.0666 0.195
Plasmodium vivax amine transporter, putative 0.0108 0.0253 0.0737
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0031 0.0032 0.003
Mycobacterium ulcerans hypothetical protein 0.0109 0.0254 0.0954
Schistosoma mansoni hypothetical protein 0.0231 0.0601 0.0609
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0074 0.0155 0.0266
Schistosoma mansoni nephrin 0.0057 0.0107 0.0108
Echinococcus multilocularis ryanodine receptor 44f 0.0031 0.0032 0.003
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0045 0.0128
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0036 0.0046 0.0172
Trichomonas vaginalis glucosylceramidase, putative 0.077 0.2131 0.5341
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0031 0.0032 0.0031
Schistosoma mansoni cpg binding protein 0.0028 0.0023 0.0023
Brugia malayi SET domain containing protein 0.0042 0.0065 0.0112
Echinococcus granulosus lipoxygenase domain containing protein 0.0159 0.0396 0.0394
Schistosoma mansoni bromodomain containing protein 0.0067 0.0135 0.0135
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.03 0.0299
Echinococcus multilocularis transient receptor potential cation channel 0.0031 0.0032 0.003
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0024 0.0012 0.0011
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0231 0.0601 0.06
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0023 0.001 0.0009
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0034 0.0041 0.0454
Echinococcus granulosus thyroid hormone receptor alpha 0.0023 0.001 0.0009
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0001 0.0004
Loa Loa (eye worm) apoptosis regulator protein 0.0085 0.0187 0.0353
Giardia lamblia [2Fe-2S] ferredoxin 0.0022 0.0006 0.0017
Mycobacterium leprae Possible regulatory protein 0.0038 0.0053 0.0165
Brugia malayi nuclear hormone receptor family member odr-7 0.0023 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0058 0.011 0.0108
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0226 0.0587 0.2205
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0121 0.0122
Echinococcus granulosus geminin 0.0855 0.2373 0.2373
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0132 0.0318 0.0317
Schistosoma mansoni hypothetical protein 0.0244 0.0637 0.0646
Treponema pallidum cyclic nucleotide binding protein 0.0024 0.0012 0.0043
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.006 0.0115 0.1276
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0034 0.0041 0.0042
Schistosoma mansoni cpg binding protein 0.0031 0.0034 0.0033
Trichomonas vaginalis xanthine dehydrogenase, putative 0.067 0.1846 0.4627
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0037 0.0049 0.0545
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0231 0.0601 0.06
Giardia lamblia Glutamate synthase 0.0254 0.0666 0.2498
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0054 0.0099 0.0099
Echinococcus granulosus sodium and chloride dependent glycine 0.0108 0.0253 0.0252
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0051 0.0091 0.0091
Schistosoma mansoni aryl hydrocarbon receptor 0.0147 0.0363 0.0367
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.002 0.0001 0.0003
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0058 0.011 0.0321
Echinococcus multilocularis sodium and chloride dependent glycine 0.0108 0.0253 0.0252
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0075 0.0157 0.0165
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0124 0.0124
Loa Loa (eye worm) G-protein coupled receptor 0.0231 0.0601 0.1134
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.0171
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0108 0.0114
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Entamoeba histolytica disulphide oxidoreductase, putative 0.0254 0.0666 0.7406
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0115 0.0285
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0254 0.0666 0.1666
Brugia malayi hypothetical protein 0.0026 0.0018 0.0032
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0207
Loa Loa (eye worm) CYP4Cod1 0.0101 0.0232 0.0438
Brugia malayi Melatonin receptor type 1A 0.0231 0.0601 0.1032
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0254 0.0666 0.0664
Loa Loa (eye worm) hypothetical protein 0.0108 0.0253 0.0477
Loa Loa (eye worm) hypothetical protein 0.0108 0.0253 0.0477
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0024 0.0012 0.0011
Trichomonas vaginalis Ferredoxin 1 0.0022 0.0006 0.0012
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Echinococcus multilocularis GPCR, family 2 0.0047 0.0078 0.0077
Echinococcus granulosus potassium large conductance calcium activated 0.0031 0.0032 0.003
Brugia malayi Associated with TFs and helicases family protein 0.0035 0.0045 0.0077
Echinococcus granulosus nuclear receptor nhr 48 0.0023 0.001 0.0009
Echinococcus granulosus g protein coupled receptor 0.0231 0.0601 0.06
Giardia lamblia Kinase, CMGC MAPK 0.0204 0.0524 0.1967
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0085 0.0187 0.0186
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0031 0.0032 0.0054
Echinococcus multilocularis somatostatin receptor 0.0231 0.0601 0.06
Schistosoma mansoni inositol monophosphatase 0.0186 0.0472 0.0478
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0085 0.0187 0.0189
Echinococcus granulosus transient receptor potential cation channel 0.0031 0.0032 0.003
Brugia malayi hypothetical protein 0.0159 0.0396 0.0679
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0075 0.0157 0.0459
Plasmodium vivax multidomain scavenger receptor, putative 0.0159 0.0396 0.1155
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0054 0.0099 0.0098
Echinococcus granulosus zinc finger protein 0.0022 0.0007 0.0005
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0069 0.014 0.0147
Echinococcus granulosus two pore calcium channel protein 1 0.0031 0.0032 0.003
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0254 0.0666 0.0664
Trypanosoma brucei electron transfer protein, putative 0.0022 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0108 0.0253 0.0477
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.007 0.0142 0.015
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0254 0.0666 0.2502
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0204 0.0524 0.0556
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0022
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0187 0.0476 0.0482
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0031 0.0032 0.0054
Loa Loa (eye worm) carboxylesterase 0.0058 0.011 0.0207
Loa Loa (eye worm) hypothetical protein 0.0042 0.0065 0.0122
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0036 0.0046 0.0047
Leishmania major hypothetical protein, unknown function 0.0024 0.0012 0.0011
Trichomonas vaginalis glutamate synthase, putative 0.0254 0.0666 0.1666
Schistosoma mansoni steroid hormone receptor ad4bp 0.0049 0.0084 0.0084
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.007 0.0142 0.0141
Onchocerca volvulus 0.0049 0.0084 0.0211
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0031 0.0032 0.0054
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0254 0.0666 0.1947
Onchocerca volvulus 0.0231 0.0601 0.1507
Echinococcus multilocularis transient receptor potential cation channel 0.0031 0.0032 0.003
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0254 0.0666 0.0707
Brugia malayi Fibronectin type III domain containing protein 0.0057 0.0107 0.0184
Echinococcus multilocularis fmrfamide receptor 0.0231 0.0601 0.06
Schistosoma mansoni lozenge 0.0058 0.011 0.0111
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0187 0.0476 0.0474
Echinococcus multilocularis aryl hydrocarbon receptor 0.0038 0.0053 0.0052
Loa Loa (eye worm) cytochrome P450 family protein 0.017 0.0428 0.0808
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.006 0.0115 0.0334
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0204 0.0524 0.0556
Brugia malayi Doublecortin family protein 0.0159 0.0396 0.0679
Onchocerca volvulus 0.0023 0.001 0.0026
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0231 0.0601 0.0609
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0254 0.0666 0.0664
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0049 0.0084 0.0084
Echinococcus granulosus neuroglian 0.0051 0.0091 0.009
Loa Loa (eye worm) hypothetical protein 0.0049 0.0085 0.016
Schistosoma mansoni hypothetical protein 0.0855 0.2373 0.2409
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0186 0.0472 0.5255
Onchocerca volvulus 0.1424 0.399 1
Onchocerca volvulus 0.0231 0.0601 0.1507
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0254 0.0666 0.0664
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0324 0.081
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0024 0.0012 0.0011
Schistosoma mansoni zinc finger protein 0.0023 0.001 0.0009
Echinococcus multilocularis potassium voltage gated channel protein 0.0031 0.0032 0.003
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0045 0.0109
Trichomonas vaginalis glucosylceramidase, putative 0.0505 0.1379 0.3456
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0072 0.007
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0124 0.0308
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0434
Schistosoma mansoni cell adhesion molecule 0.0066 0.0131 0.0132
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0207
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0054 0.0099 0.0099
Trypanosoma cruzi NADH dehydrogenase, putative 0.0254 0.0666 0.0707
Entamoeba histolytica hypothetical protein 0.0035 0.0045 0.0496
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0046 0.0048
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.007 0.007
Loa Loa (eye worm) programmed cell death 8 0.0254 0.0666 0.1256
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0066 0.0133 0.0333
Echinococcus multilocularis zinc finger protein 0.0022 0.0007 0.0005
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0231 0.0601 0.0609
Trypanosoma cruzi Flagellar Member 6 0.0024 0.0012 0.0011
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0024 0.0012 0.0031
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0254 0.0666 0.0707
Schistosoma mansoni growth hormone secretagogue receptor 0.0231 0.0601 0.0609
Loa Loa (eye worm) norepinephrine transporter 0.0639 0.176 0.332
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.006 0.0116 0.0122
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.006 0.0116 0.0122
Plasmodium vivax ferrodoxin reductase, putative 0.0254 0.0666 0.1947
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.018 0.0456 0.1337
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0024 0.0012 0.0011
Leishmania major hypothetical protein, unknown function 0.0031 0.0032 0.0032
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0186 0.0472 0.0501
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0254 0.0666 0.0707
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Mycobacterium tuberculosis Probable oxidoreductase 0.0022 0.0006 0.0017
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0231 0.0601 0.06
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0046 0.0077 0.0076
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.018 0.0455 0.0461
Schistosoma mansoni alpha-1 adrenergic receptor 0.0231 0.0601 0.0609
Loa Loa (eye worm) hypothetical protein 0.0159 0.0396 0.0746
Echinococcus granulosus chromobox protein 1 0.0094 0.0212 0.0211
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0173 0.0437 0.0825
Trichomonas vaginalis glucosylceramidase, putative 0.0505 0.1379 0.3456
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0038 0.0053 0.0131
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0045 0.0128
Loa Loa (eye worm) hypothetical protein 0.0254 0.0666 0.1256
Brugia malayi AKH receptor 0.0231 0.0601 0.1032
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.006 0.0114 0.0216
Trichomonas vaginalis PIKK family atypical protein kinase 0.0106 0.0246 0.0615
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0031 0.0032 0.003
Schistosoma mansoni hypothetical protein 0.0035 0.0045 0.0044
Echinococcus granulosus nuclear factor of activated T cells 5 0.0215 0.0554 0.0553
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0037 0.0049 0.0048
Brugia malayi jmjC domain containing protein 0.0063 0.0124 0.0212
Chlamydia trachomatis endonuclease IV 0.0074 0.0155 0.0578
Loa Loa (eye worm) phosphofructokinase 0.0222 0.0575 0.1085
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0035 0.0045 0.0077
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0075 0.0157 0.0459
Brugia malayi hypothetical protein 0.0223 0.0577 0.099
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0231 0.0601 0.1032
Mycobacterium ulcerans electron transfer protein FdxB 0.0022 0.0006 0.0022
Trichomonas vaginalis Ferredoxin 3 0.0022 0.0006 0.0012
Echinococcus granulosus BC026374 protein S09 family 0.0058 0.011 0.0108
Echinococcus granulosus tar DNA binding protein 0.0062 0.0121 0.012
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0024 0.0012 0.0035
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0049 0.0084 0.0083
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.03 0.0318
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0022 0.0006 0.001
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0231 0.0601 0.06
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0324 0.081
Schistosoma mansoni transient receptor potential channel 0.0031 0.0032 0.0031
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0222 0.0575 0.2161
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0115 0.0285
Echinococcus multilocularis neuropeptide receptor 0.0231 0.0601 0.06
Schistosoma mansoni glutamate synthase 0.0254 0.0666 0.0675
Echinococcus multilocularis ATP binding cassette sub family G 0.0036 0.0046 0.0044
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0037 0.0049 0.0121
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0085
Echinococcus multilocularis voltage gated potassium channel 0.0068 0.0138 0.0136
Echinococcus granulosus potassium voltage gated channel protein 0.0031 0.0032 0.003
Loa Loa (eye worm) glutathione reductase 0.1221 0.3414 0.644
Trypanosoma brucei Flagellar Member 6 0.0024 0.0012 0.0011
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0254 0.0666 0.0664
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0116 0.0287
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.018 0.0455 0.0454
Trypanosoma brucei trypanothione reductase 0.1221 0.3414 0.363
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trypanosoma brucei DNA topoisomerase ii 0.006 0.0114 0.012
Echinococcus granulosus g protein coupled receptor 0.0231 0.0601 0.06
Loa Loa (eye worm) hypothetical protein 0.0344 0.0921 0.1738
Trichomonas vaginalis DNA topoisomerase II, putative 0.0078 0.0167 0.0416
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.001 0.0026
Mycobacterium ulcerans carboxylesterase, LipT 0.0058 0.011 0.0412
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0046 0.0048
Echinococcus multilocularis hyperpolarization activated cyclic 0.0054 0.0099 0.0098
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0075 0.0157 0.0459
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0128 0.0308 0.1157
Onchocerca volvulus 0.0231 0.0601 0.1507
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0037 0.0049 0.0141
Echinococcus granulosus somatostatin receptor 0.0231 0.0601 0.06
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0024 0.0012 0.0011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0078 0.0134
Trichomonas vaginalis Ferredoxin 6 0.0022 0.0006 0.0012
Trypanosoma brucei ATP-binding cassette protein, putative 0.0036 0.0046 0.0047
Echinococcus granulosus neuropeptide receptor A26 0.1158 0.3234 0.3233
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0031 0.0032 0.0032
Schistosoma mansoni loxhd1 0.0159 0.0396 0.04
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0231 0.0601 0.06
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0031 0.0032 0.003
Onchocerca volvulus 0.0106 0.0247 0.0619
Brugia malayi cation channel family protein 0.0031 0.0032 0.0054
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.018 0.0456 0.0784
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0108 0.0114
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.006 0.0115 0.0334
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0173 0.0437 0.0751
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0078 0.0167 0.0177
Leishmania major hypothetical protein, conserved 0.0024 0.0012 0.0011
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0031 0.0032 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0053 0.0131
Treponema pallidum thioredoxin reductase (trxB) 0.0254 0.0666 0.25
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.018 0.0456 0.0462
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0072 0.007
Echinococcus multilocularis allatostatin A receptor 0.0231 0.0601 0.06
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0045 0.0494
Plasmodium vivax ferredoxin, putative 0.0022 0.0006 0.0014
Echinococcus granulosus Adrenodoxin mitochondrial 0.0022 0.0006 0.0005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0024 0.0012 0.0035
Loa Loa (eye worm) phosphatidylinositol 3 0.018 0.0455 0.0858
Schistosoma mansoni biogenic amine receptor 0.0231 0.0601 0.0609
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0049 0.0084 0.0084
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0022 0.0006 0.0017
Loa Loa (eye worm) cytochrome P450 family protein 0.0101 0.0232 0.0438
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0024 0.0012 0.0011
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.007 0.0142 0.0414
Schistosoma mansoni sulfide quinone reductase 0.0254 0.0666 0.0675
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Schistosoma mansoni DNA topoisomerase II 0.0078 0.0167 0.0169
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.018 0.0456 0.1716
Brugia malayi Carboxylesterase family protein 0.0058 0.011 0.0188
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0186 0.0472 0.1776
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0108 0.0107
Brugia malayi neuropeptide F receptor 0.0231 0.0601 0.1032
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0024 0.0012 0.0027
Loa Loa (eye worm) nuclear receptor NHR-67 0.0023 0.001 0.002
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0078 0.0167 0.0177
Echinococcus granulosus mitogen activated protein kinase 0.0204 0.0524 0.0523
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0075 0.0157 0.0589
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0254 0.0666 0.1666
Brugia malayi G protein-coupled receptor F59B2.13 0.0231 0.0601 0.1032
Echinococcus multilocularis potassium voltage gated channel protein 0.0031 0.0032 0.003
Loa Loa (eye worm) SRC-1 0.0046 0.0077 0.0145
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0075 0.0157 0.0165
Echinococcus granulosus acetylcholinesterase 0.0344 0.0921 0.092
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0075 0.0157 0.0589
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0038 0.0053 0.0055
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.004 0.0059 0.0061
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0031 0.0032 0.0032
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0031 0.0032 0.003
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0956 0.2661 1
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0039 0.0055 0.0055
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0108 0.0402
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.03 0.0303
Echinococcus multilocularis neuropeptide receptor 0.0231 0.0601 0.06
Onchocerca volvulus 0.0031 0.0032 0.0079
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0054 0.0099 0.0098
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0254 0.0666 0.1947
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0005 0.001
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.005 0.0049
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0084 0.0083
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0024 0.0012 0.0011
Echinococcus granulosus neuropeptide s receptor 0.1158 0.3234 0.3233
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.1067 0.1066
Brugia malayi Inositol-1 0.0186 0.0472 0.0811
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0001 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.333 0.9402 1
Leishmania major ferredoxin, 2fe-2s-like protein 0.0022 0.0006 0.0005
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0054 0.0099 0.0099
Echinococcus granulosus GPCR family 2 0.0047 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0092
Plasmodium falciparum DNA topoisomerase 2 0.0078 0.0167 0.0486
Trichomonas vaginalis spcc417.12 protein, putative 0.0058 0.011 0.0272
Entamoeba histolytica hypothetical protein 0.0035 0.0045 0.0496
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0016
Loa Loa (eye worm) runx1 0.0058 0.011 0.0208
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0108 0.0253 0.0255
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0024 0.0012 0.0011
Giardia lamblia Fructose-bisphosphate aldolase 0.0301 0.0801 0.3006
Onchocerca volvulus 0.0023 0.001 0.0026
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0956 0.2661 0.7793
Toxoplasma gondii hypothetical protein 0.0108 0.0253 0.0737
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0058 0.011 0.011
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0024 0.0012 0.0022
Leishmania major hypothetical protein, conserved 0.0254 0.0666 0.0707
Trypanosoma cruzi DNA topoisomerase II, putative 0.0078 0.0167 0.0177
Schistosoma mansoni survival motor neuron protein 0.0244 0.0637 0.0646
Echinococcus granulosus voltage gated potassium channel 0.0068 0.0138 0.0136
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.077 0.2131 0.5341
Entamoeba histolytica phosphofructokinase, putative 0.0222 0.0575 0.64
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.018 0.0456 0.0484
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0476 0.0482
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0037 0.0049 0.0093
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0254 0.0666 0.2502
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0024 0.0012 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.006 0.0116 0.0115
Brugia malayi bHLH-PAS transcription factor 0.0109 0.0254 0.0436
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0023 0.001 0.0009
Onchocerca volvulus 0.0231 0.0601 0.1507
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0075 0.0157 0.0589
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0042 0.0063 0.0154
Schistosoma mansoni nuclear hormone receptor 0.0023 0.001 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0231 0.0601 0.06
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0254 0.0666 0.0707
Loa Loa (eye worm) hepatopoietin HPO2 0.007 0.0142 0.0269
Schistosoma mansoni chromobox protein 0.0094 0.0212 0.0214
Echinococcus multilocularis g protein coupled receptor 0.0231 0.0601 0.06
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0115 0.0285
Onchocerca volvulus Dual oxidase homolog 0.0146 0.036 0.0903
Loa Loa (eye worm) hypothetical protein 0.0101 0.0233 0.0439
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0024 0.0012 0.0031
Echinococcus multilocularis conserved hypothetical protein 0.2758 0.7777 0.7777
Mycobacterium tuberculosis Probable reductase 0.0455 0.1238 0.3627
Echinococcus granulosus rhodopsin orphan GPCR 0.0231 0.0601 0.06
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0124 0.0123
Schistosoma mansoni gliotactin 0.0058 0.011 0.011
Echinococcus granulosus single minded 2 0.0123 0.0293 0.0292
Loa Loa (eye worm) hypothetical protein 0.0063 0.0124 0.0234
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0018 0.0032
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0036 0.0046 0.0172
Mycobacterium ulcerans monoxygenase 0.0254 0.0666 0.2502
Echinococcus granulosus short transient receptor potential channel 6 0.0031 0.0032 0.003
Trypanosoma cruzi ABC transporter, putative 0.0036 0.0046 0.0047
Schistosoma mansoni amine GPCR 0.0231 0.0601 0.0609
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0075 0.0157 0.0589
Loa Loa (eye worm) hypothetical protein 0.0085 0.0187 0.0353
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0231 0.0601 0.0609
Echinococcus granulosus 6 phosphofructokinase 0.0222 0.0575 0.0574
Leishmania major hypothetical protein, conserved 0.0031 0.0032 0.0032
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0075 0.0157 0.0589
Trypanosoma cruzi NADH dehydrogenase, putative 0.0254 0.0666 0.0707
Brugia malayi Heterochromatin protein 1 0.0094 0.0212 0.0364
Echinococcus granulosus ecdysone induced protein 78C 0.0049 0.0084 0.0083
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0049 0.0084 0.0159
Echinococcus multilocularis dro:myosuppressin receptor 0.0231 0.0601 0.06
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0046 0.0045
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0115 0.0285
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0254 0.0666 0.1947
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0075 0.0157 0.0459
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0108 0.0314
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0215 0.0554 0.0553
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0131 0.0131
Loa Loa (eye worm) hypoxia-induced factor 1 0.0456 0.1238 0.2336
Echinococcus granulosus twitchin 0.0053 0.0096 0.0095
Brugia malayi PAS domain containing protein 0.0147 0.0363 0.0623
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0039 0.0055 0.0054
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0054 0.0099 0.0186
Leishmania major dihydrolipoamide dehydrogenase, putative 0.333 0.9402 1
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.004 0.0059 0.0061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0063 0.0154
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0254 0.0666 0.1256
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0049 0.0084 0.0159
Echinococcus multilocularis inositol monophosphatase 1 0.0186 0.0472 0.0471
Schistosoma mansoni hypothetical protein 0.0031 0.0032 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0041 0.01
Leishmania major acetoin dehydrogenase e3 component-like protein 0.2458 0.6927 0.7367
Giardia lamblia GTOR 0.018 0.0455 0.1705
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.018 0.0455 0.0454
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0702 0.194 0.3331
Echinococcus multilocularis potassium voltage gated channel protein 0.0031 0.0032 0.003
Echinococcus multilocularis g protein coupled receptor 0.0231 0.0601 0.06
Onchocerca volvulus 0.0639 0.176 0.441
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Loa Loa (eye worm) hypothetical protein 0.0058 0.0111 0.0209
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0254 0.0666 0.0664
Onchocerca volvulus 0.0231 0.0601 0.1507
Entamoeba histolytica hypothetical protein 0.0035 0.0045 0.0496
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0075 0.0157 0.0459
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0639 0.176 0.1785
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0222 0.0575 0.1685
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143 0.035 0.0876
Schistosoma mansoni microtubule-associated protein tau 0.3487 0.985 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0075 0.0157 0.0459
Schistosoma mansoni BC026374 protein (S09 family) 0.0058 0.011 0.011
Echinococcus granulosus RUN 0.0159 0.0396 0.0394
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0084 0.0145
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0004 0.0003
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0444 0.1204 0.4527
Schistosoma mansoni 6-phosphofructokinase 0.0222 0.0575 0.0583
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0045 0.0494
Brugia malayi Nuclear hormone receptor-like 1 0.0049 0.0084 0.0145
Schistosoma mansoni ryanodine receptor related 0.0031 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.1886 0.5301 1
Brugia malayi CXXC zinc finger family protein 0.0028 0.0023 0.004
Trichomonas vaginalis chromobox protein, putative 0.0066 0.0133 0.033
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0198 0.0508 0.1911
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0031 0.0032 0.0054
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0045 0.0044
Schistosoma mansoni zinc finger protein 0.0022 0.0007 0.0005
Schistosoma mansoni amine GPCR 0.0231 0.0601 0.0609
Trichomonas vaginalis guanylate cyclase, putative 0.0038 0.0053 0.0131
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0036 0.0046 0.0047
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.0366 0.0629
Echinococcus granulosus tyrosine kinase 0.0043 0.0066 0.0065
Schistosoma mansoni cytochrome P450 0.0075 0.0157 0.0158
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.001 0.0009
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0038 0.0053 0.0131
Plasmodium falciparum ABC transporter G family member 2 0.0036 0.0046 0.013
Onchocerca volvulus 0.0222 0.0576 0.1443
Loa Loa (eye worm) hypothetical protein 0.0464 0.1264 0.2385
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0222 0.0575 0.1779
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0231 0.0601 0.0609
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0031 0.0032 0.003
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0231 0.0244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0153 0.038 0.095
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Trichomonas vaginalis guanylate cyclase, putative 0.0038 0.0053 0.0131
Echinococcus granulosus chromobox protein 1 0.0094 0.0212 0.0211
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0477
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.354 1 1
Schistosoma mansoni rab6-interacting 0.0159 0.0396 0.04
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0108 0.0402
Onchocerca volvulus 0.0215 0.0556 0.1393
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.006 0.0115 0.0431
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0031 0.0032 0.0054
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0206 0.0529 0.1326
Brugia malayi voltage-dependent calcium channel 0.0031 0.0032 0.0054
Plasmodium vivax 6-phosphofructokinase, putative 0.006 0.0115 0.0334
Echinococcus granulosus lysine specific demethylase 5A 0.0063 0.0124 0.0123
Echinococcus granulosus cytochrome P450 2K1 0.0075 0.0157 0.0155
Schistosoma mansoni biogenic amine (5HT) receptor 0.06 0.1649 0.1673
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0031 0.0032 0.003
Echinococcus granulosus transient receptor potential cation channel 0.0031 0.0032 0.003
Echinococcus granulosus glutamate synthase 0.0254 0.0666 0.0664
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Chlamydia trachomatis thioredoxin reductase 0.0254 0.0666 0.2498
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0956 0.2661 0.7793
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0254 0.0666 0.1947
Plasmodium vivax thioredoxin reductase, putative 0.1221 0.3414 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0108 0.0114
Loa Loa (eye worm) hypothetical protein 0.0049 0.0085 0.016
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.077 0.2131 0.366
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0254 0.0666 0.1947
Schistosoma mansoni lipoxygenase 0.0412 0.1114 0.113
Echinococcus multilocularis two pore calcium channel protein 1 0.0031 0.0032 0.003
Brugia malayi putative neuropeptide receptor 0.0231 0.0601 0.1032
Echinococcus multilocularis lamin 0.0106 0.0247 0.0246
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0024 0.0012 0.0011
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0254 0.0666 0.0707
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0956 0.2661 1
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0031 0.0032 0.0031
Schistosoma mansoni neuropeptide F-like receptor 0.0231 0.0601 0.0609
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0254 0.0666 0.0664
Entamoeba histolytica hypothetical protein 0.0035 0.0045 0.0494
Echinococcus granulosus aryl hydrocarbon receptor 0.0038 0.0053 0.0052
Trichomonas vaginalis glucosylceramidase, putative 0.077 0.2131 0.5341
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0046 0.0077 0.0076
Brugia malayi Steroid receptor seven-up type 2 0.0049 0.0084 0.0145
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0075 0.0157 0.0459
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.0041 0.004
Plasmodium falciparum transporter, putative 0.0108 0.0253 0.0737
Schistosoma mansoni neuropeptide receptor 0.0231 0.0601 0.0609
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0038 0.0053 0.0055
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0031 0.0032 0.0079
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0075 0.0157 0.0589
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0063 0.0154
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0108 0.0253 0.0252
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0031 0.0032 0.0031
Brugia malayi photoreceptor-specific nuclear receptor 0.0049 0.0084 0.0145
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0024 0.0012 0.0031
Echinococcus granulosus tm gpcr rhodopsin 0.0231 0.0601 0.06
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0147 0.0363 0.1364
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0038 0.0053 0.0052
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0054 0.0099 0.0249
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0124 0.0233
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0045 0.0109
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0024 0.0012 0.0011
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0121 0.0229
Onchocerca volvulus 0.0231 0.0601 0.1507
Echinococcus granulosus survival motor neuron protein 1 0.1195 0.3339 0.3338
Loa Loa (eye worm) voltage-gated potassium channel 0.0031 0.0032 0.006
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0049 0.0084 0.0211
Onchocerca volvulus 0.0028 0.0023 0.0059
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0231 0.0601 0.06
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0273
Mycobacterium ulcerans oxidoreductase 0.0022 0.0006 0.0022
Toxoplasma gondii phosphofructokinase domain-containing protein 0.006 0.0115 0.0334
Onchocerca volvulus 0.0108 0.0253 0.0634
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0024 0.0012 0.002
Leishmania major ATP-dependent phosphofructokinase 0.0222 0.0575 0.0611
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Schistosoma mansoni 6-phosphofructokinase 0.0222 0.0575 0.0583
Treponema pallidum catabolite gene activator 0.0024 0.0012 0.0043
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0045 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.022 0.0549
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0737
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0124 0.0124
Toxoplasma gondii exonuclease III APE 0.0058 0.0108 0.0314
Mycobacterium ulcerans oxidoreductase 0.0022 0.0006 0.0022
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0068 0.0138 0.0136
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.006 0.0115 0.0428
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Brugia malayi jmjC domain containing protein 0.0059 0.0114 0.0195
Schistosoma mansoni coup transcription factor 0.0049 0.0084 0.0084
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.0233 0.04
Schistosoma mansoni hypothetical protein 0.0159 0.0396 0.04
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1158 0.3233 0.947
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0024 0.0012 0.0031
Trichomonas vaginalis glutaminase, putative 0.0267 0.0704 0.1762
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0042 0.0064 0.0062
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0254 0.0666 0.1666
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0114 0.0112
Entamoeba histolytica DNA topoisomerase II, putative 0.0078 0.0167 0.1857
Brugia malayi Protein cec-1. 0.0035 0.0045 0.0077
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Schistosoma mansoni hypothetical protein 0.0085 0.0187 0.0189
Loa Loa (eye worm) hypothetical protein 0.0639 0.176 0.332
Trichomonas vaginalis glutamate synthase, putative 0.0254 0.0666 0.1666
Loa Loa (eye worm) hypothetical protein 0.0039 0.0054 0.0102
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0046 0.0077 0.0076
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.018 0.0456 0.0455
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0254 0.0666 0.1143
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0536 0.1467 0.252
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.001 0.0026
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0231 0.0601 0.06
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus granulosus acetylcholinesterase 0.0344 0.0921 0.092
Plasmodium vivax ataxin-2 like protein, putative 0.0101 0.0231 0.0673
Loa Loa (eye worm) solute carrier family 6 member 4 0.0639 0.176 0.332
Echinococcus multilocularis neuropeptide Y receptor 0.0231 0.0601 0.06
Echinococcus granulosus tyrosine protein kinase HCK 0.0039 0.0055 0.0054
Brugia malayi cation channel family protein 0.0031 0.0032 0.0054
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0022 0.0006 0.001
Schistosoma mansoni hypothetical protein 0.0275 0.0724 0.0734
Schistosoma mansoni ap endonuclease 0.0058 0.0108 0.0109
Brugia malayi Uncoordinated protein 44 0.0042 0.0064 0.0109
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Echinococcus granulosus cGMP dependent protein kinase 1 0.0025 0.0017 0.0016
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0231 0.0601 0.0609
Trichomonas vaginalis glucosylceramidase, putative 0.0505 0.1379 0.3456
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0023 0.001 0.002
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0054 0.0099 0.0099
Mycobacterium ulcerans 6-phosphofructokinase 0.0222 0.0575 0.2162
Toxoplasma gondii transporter, cation channel family protein 0.0031 0.0032 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0024 0.0057
Echinococcus granulosus sodium channel protein 0.0241 0.0629 0.0628
Echinococcus granulosus fmrfamide receptor 0.0231 0.0601 0.06
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0034 0.0041 0.004
Echinococcus granulosus para nitrobenzyl esterase 0.0058 0.011 0.0108
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0031 0.0032 0.0054
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus multilocularis chromobox protein 2 0.0035 0.0045 0.0044
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0068 0.0139 0.0263
Toxoplasma gondii DNA topoisomerase 2, putative 0.0078 0.0167 0.0486
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0035 0.0045 0.0128
Echinococcus granulosus tm gpcr rhodopsin 0.0231 0.0601 0.06
Onchocerca volvulus Glucosylceramidase homolog 0.0505 0.1379 0.3457
Loa Loa (eye worm) hypothetical protein 0.0106 0.0247 0.0466
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2808 0.7919 0.8422
Echinococcus multilocularis calcium activated potassium channel 0.0032 0.0037 0.0036
Brugia malayi hypothetical protein 0.0065 0.0129 0.0222
Echinococcus granulosus neuropeptide receptor 0.0231 0.0601 0.06
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0024 0.0013 0.0038
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0108 0.0314
Entamoeba histolytica hypothetical protein 0.0035 0.0045 0.0494
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0249 0.0623
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.001 0.0009
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.006 0.0116 0.0122
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Mycobacterium ulcerans oxygenase 0.0022 0.0006 0.0022
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0024 0.0012 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0022 0.0006 0.0022
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.001 0.0009
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0038 0.0052 0.0149
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0434
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0046 0.0077 0.0076
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0254 0.0666 0.1143
Echinococcus granulosus g protein coupled receptor 0.0231 0.0601 0.06
Brugia malayi SRC-1 0.0046 0.0077 0.0132
Onchocerca volvulus 0.0231 0.0601 0.1507
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0031 0.0032 0.0054
Brugia malayi Dopamine receptor protein 1 0.0231 0.0601 0.1032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0082 0.0201
Echinococcus multilocularis neuroligin 0.0058 0.011 0.0108
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0231 0.0601 0.0609
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1471 0.4124 0.7083
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0054 0.0099 0.0249
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0226 0.0587 0.1008
Loa Loa (eye worm) doublecortin family protein 0.0159 0.0396 0.0746
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0031 0.0032 0.0054
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Schistosoma mansoni lamin 0.0106 0.0247 0.0249
Echinococcus granulosus potassium voltage gated channel protein 0.0031 0.0032 0.003
Onchocerca volvulus 0.0058 0.011 0.0275
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0025 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.06 0.1649 0.3111
Brugia malayi hypothetical protein 0.0057 0.0107 0.0184
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0231 0.0601 0.06
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0231 0.0601 0.06
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.03 0.0303
Brugia malayi Protein kinase domain containing protein 0.0044 0.0069 0.0118
Schistosoma mansoni chromobox protein 0.0094 0.0212 0.0214
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0037 0.0049 0.0121
Echinococcus multilocularis sex peptide receptor 0.0231 0.0601 0.06
Loa Loa (eye worm) ion channel NompC 0.0031 0.0032 0.006
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.0066 0.0065
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.004 0.0059 0.0061
Loa Loa (eye worm) hypothetical protein 0.0536 0.1467 0.2768
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0108 0.0253 0.0252
Echinococcus multilocularis neuroglian 0.0051 0.0091 0.009
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0037 0.0049 0.0051
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0956 0.2661 0.266
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0075 0.0157 0.0459
Loa Loa (eye worm) RecQ helicase 0.0021 0.0004 0.0008
Toxoplasma gondii LsmAD domain-containing protein 0.0101 0.0231 0.0673
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0069 0.014 0.0147
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0031 0.0032 0.0031
Schistosoma mansoni voltage-gated cation channel 0.0031 0.0032 0.0031
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0051 0.009 0.0089
Leishmania major protein kinase, putative 0.004 0.0059 0.0061
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.03 0.0299
Echinococcus multilocularis potassium voltage gated channel protein 0.0031 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Schistosoma mansoni intermediate filament proteins 0.0106 0.0247 0.0249
Onchocerca volvulus 0.0031 0.0033 0.0082
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0075 0.0157 0.0459
Mycobacterium tuberculosis Probable oxidoreductase 0.1158 0.3233 0.947
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0231 0.0601 0.06
Echinococcus granulosus dnaJ subfamily B 0.0395 0.1067 0.1066
Brugia malayi M-phase phosphoprotein, mpp8 0.0222 0.0576 0.0989
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Toxoplasma gondii thioredoxin reductase 0.1221 0.3414 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0207
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0032 0.0089
Onchocerca volvulus 0.0244 0.0637 0.1596
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0128 0.0308 0.1157
Mycobacterium tuberculosis Probable dehydrogenase 0.0455 0.1238 0.3627
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Schistosoma mansoni glutamate synthase 0.0254 0.0666 0.0675
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0023 0.001 0.0009
Schistosoma mansoni opsin-like receptor 0.0231 0.0601 0.0609
Schistosoma mansoni adenoreceptor 0.0231 0.0601 0.0609
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.006 0.0114 0.012
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0186 0.0472 0.0501
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0045 0.0044
Onchocerca volvulus 0.0109 0.0254 0.0637
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0031 0.0032 0.003
Brugia malayi nuclear hormone receptor 0.0023 0.001 0.0018
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0187 0.0476 0.0482
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0455 0.1238 0.3627
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0024 0.0012 0.0031
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0204 0.0524 0.0556
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.018 0.0455 0.0482
Brugia malayi PHD-finger family protein 0.0027 0.0022 0.0038
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0031 0.0032 0.003
Brugia malayi glutathione reductase 0.1221 0.3414 0.5863
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0049 0.0084 0.0159
Loa Loa (eye worm) hypothetical protein 0.0148 0.0366 0.0691
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0045 0.0044
Echinococcus granulosus Chromobox protein 3 0.0035 0.0045 0.0044
Echinococcus granulosus G protein coupled receptor 139 0.0231 0.0601 0.06
Trichomonas vaginalis apoptosis inducing factor, putative 0.0254 0.0666 0.1666
Loa Loa (eye worm) hypothetical protein 0.0226 0.0587 0.1107
Giardia lamblia Thioredoxin reductase 0.0254 0.0666 0.2498
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0084 0.0145
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0042 0.0064 0.0062
Loa Loa (eye worm) hypothetical protein 0.0068 0.0138 0.026
Echinococcus multilocularis ecdysone induced protein 78C 0.0049 0.0084 0.0083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0249 0.0623
Leishmania major hypothetical protein, conserved 0.0254 0.0666 0.0707
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0078 0.0077
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0075 0.0157 0.0589
Loa Loa (eye worm) hypothetical protein 0.0329 0.0878 0.1656
Echinococcus granulosus intermediate filament protein 0.0106 0.0247 0.0246
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.006 0.0116 0.0199
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.2808 0.7919 0.8422
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.077 0.2131 0.4021
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0737
Plasmodium falciparum amino acid transporter, putative 0.0108 0.0253 0.0737
Schistosoma mansoni hypothetical protein 0.0047 0.0078 0.0078
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.002 0.0001 0.0004
Echinococcus granulosus roundabout 2 0.0066 0.0131 0.013
Echinococcus multilocularis shaker cognate 0.0031 0.0032 0.003
Leishmania major ferredoxin 2fe-2s-like protein 0.0022 0.0006 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Brugia malayi nuclear hormone receptor family member nhr-6 0.0023 0.001 0.0018
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.007 0.0142 0.015
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trypanosoma cruzi hypothetical protein, conserved 0.0254 0.0666 0.0707
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0032 0.0089
Echinococcus multilocularis conserved hypothetical protein 0.0031 0.0032 0.003
Trichomonas vaginalis inositol monophosphatase, putative 0.0186 0.0472 0.1181
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0075 0.0157 0.0459
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0077 0.0076
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0956 0.2661 0.2829
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0078 0.0147
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0075 0.0157 0.0459
Schistosoma mansoni sodium/chloride dependent transporter 0.011 0.0258 0.0261
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.007 0.0142 0.015
Loa Loa (eye worm) hypothetical protein 0.0639 0.176 0.332
Echinococcus granulosus TRP transient receptor potential channel 0.0031 0.0032 0.003
Trichomonas vaginalis xanthine dehydrogenase, putative 0.067 0.1846 0.4627
Trichomonas vaginalis PIKK family atypical protein kinase 0.0117 0.0276 0.0689
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Brugia malayi Immunoglobulin I-set domain containing protein 0.0068 0.0139 0.0239
Echinococcus multilocularis cpg binding protein 0.0031 0.0034 0.0032
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0254 0.0666 0.2498
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0049 0.0084 0.0159
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0057 0.0107 0.0201
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0058 0.011 0.0108
Echinococcus multilocularis Ankyrin 0.0042 0.0065 0.0063
Trypanosoma brucei cytochrome P450, putative 0.0101 0.0232 0.0245
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0108 0.0253 0.0255
Echinococcus granulosus voltage dependent calcium channel 0.0031 0.0032 0.003
Trichomonas vaginalis chromobox protein, putative 0.0094 0.0212 0.0529
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0023 0.001 0.0009
Brugia malayi N-terminal motif family protein 0.0206 0.0529 0.0909
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0031 0.0032 0.0031
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0035 0.0045 0.0044
Schistosoma mansoni rab6-interacting 0.0159 0.0396 0.04
Loa Loa (eye worm) TOPoisomerase family member 0.0078 0.0167 0.0315
Echinococcus granulosus rhodopsin orphan GPCR 0.0231 0.0601 0.06
Echinococcus granulosus potassium voltage gated channel protein 0.0031 0.0032 0.003
Entamoeba histolytica hypothetical protein 0.0035 0.0045 0.0494
Trichomonas vaginalis glucosylceramidase, putative 0.0532 0.1457 0.3649
Echinococcus granulosus tyrosine protein kinase Blk 0.0043 0.0066 0.0065
Schistosoma mansoni amine GPCR 0.0231 0.0601 0.0609
Loa Loa (eye worm) ABC transporter 0.003 0.003 0.0057
Brugia malayi Valyl-tRNA synthetase 0.0035 0.0045 0.0077
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0037 0.0049 0.0051
Onchocerca volvulus Netrin receptor homolog 0.0052 0.0094 0.0235
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0231 0.0601 0.06
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0324 0.081
Loa Loa (eye worm) G-protein coupled receptor 0.0231 0.0601 0.1134
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Entamoeba histolytica phosphofructokinase, putative 0.0222 0.0575 0.64
Echinococcus multilocularis thioredoxin glutathione reductase 0.1221 0.3414 0.3413
Schistosoma mansoni sulfide quinone reductase 0.0254 0.0666 0.0675
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0254 0.0666 0.1666
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0231 0.0673
Loa Loa (eye worm) hypothetical protein 0.0078 0.0165 0.0312
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0049 0.0084 0.0159
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0069 0.014 0.0147
Onchocerca volvulus 0.0108 0.0253 0.0634
Loa Loa (eye worm) neuropeptide F receptor 0.0231 0.0601 0.1134
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0049 0.0084 0.0083
Schistosoma mansoni jun-related protein 0.0275 0.0724 0.0734
Entamoeba histolytica protein kinase rad3, putative 0.0034 0.0041 0.0454
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0036 0.0046 0.013
Echinococcus multilocularis transient receptor potential gamma protein 0.0031 0.0032 0.003
Echinococcus granulosus transient receptor potential cation channel 0.0031 0.0032 0.003
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0024 0.0012 0.0011
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0143 0.035 0.0875
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0207
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.005 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143 0.035 0.0876
Plasmodium falciparum thioredoxin reductase 0.0956 0.2661 0.7793
Echinococcus granulosus voltage gated potassium channel 0.0031 0.0032 0.003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Mycobacterium ulcerans electron transfer protein 0.0022 0.0006 0.0022
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0049 0.0084 0.0083
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0108 0.0253 0.0255
Schistosoma mansoni chromobox protein 0.0035 0.0045 0.0044
Loa Loa (eye worm) calcium channel 0.0031 0.0032 0.006
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0054 0.0099 0.0245
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Leishmania major C-8 sterol isomerase-like protein 0.1471 0.4124 0.4386
Brugia malayi Carboxylesterase family protein 0.0058 0.011 0.0188
Plasmodium vivax SET domain protein, putative 0.018 0.0456 0.1332
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0031 0.0032 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0008 0.0018
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.018 0.0455 0.5059
Trichomonas vaginalis glucosylceramidase, putative 0.0505 0.1379 0.3456
Echinococcus multilocularis G-protein coupled receptor, putative 0.0231 0.0601 0.06
Trypanosoma cruzi cAMP response protein 1 0.0024 0.0012 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0063 0.0154
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0108 0.0253 0.0255
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0031 0.0032 0.003
Schistosoma mansoni two-pore calcium channel 0.0031 0.0032 0.0031
Loa Loa (eye worm) 6-phosphofructokinase 0.0222 0.0575 0.1085
Loa Loa (eye worm) nuclear hormone receptor 0.0023 0.001 0.002
Echinococcus multilocularis two pore calcium channel protein 2 0.0031 0.0032 0.003
Echinococcus granulosus ATP binding cassette sub family G 0.0036 0.0046 0.0044
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0063 0.0154
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0108 0.0253 0.0252
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0132 0.0318 0.0337
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0108 0.0107
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0018 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0054 0.0133
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0034 0.0041 0.004
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0031 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0075 0.0157 0.0459
Trypanosoma cruzi target of rapamycin kinase 3 0.0143 0.0351 0.0372
Brugia malayi Probable DNA topoisomerase II 0.0078 0.0167 0.0287
Echinococcus granulosus hyperpolarization activated cyclic 0.0054 0.0099 0.0098
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0042 0.0064 0.0237
Plasmodium falciparum ferrodoxin reductase-like protein 0.0254 0.0666 0.1947
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0038 0.0053 0.0131
Brugia malayi ecdysteroid receptor 0.0049 0.0084 0.0145
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0046 0.0045
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0956 0.2661 0.27
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.018 0.0455 0.0482
Echinococcus multilocularis BC026374 protein (S09 family) 0.0058 0.011 0.0108
Brugia malayi hypothetical protein 0.0249 0.0651 0.1119
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0058 0.011 0.011
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0204 0.0524 0.0989
Onchocerca volvulus Protein ultraspiracle homolog 0.0049 0.0084 0.0211
Loa Loa (eye worm) hypothetical protein 0.0344 0.0921 0.1738
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0001 0.0009
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0022 0.0006 0.0011
Schistosoma mansoni neuropeptide receptor 0.0231 0.0601 0.0609
Schistosoma mansoni voltage-gated potassium channel 0.0068 0.0138 0.0138
Plasmodium vivax DNA topoisomerase II, putative 0.0078 0.0167 0.0486
Echinococcus granulosus neuropeptide FF receptor 2 0.0231 0.0601 0.06
Leishmania major hypothetical protein, conserved 0.0024 0.0012 0.0011
Echinococcus granulosus transient receptor potential cation channel 0.0031 0.0033 0.0031
Mycobacterium ulcerans endonuclease IV 0.0074 0.0155 0.0583
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0022 0.0006 0.0015
Brugia malayi hypoxia-induced factor 1 0.0456 0.1238 0.2127
Loa Loa (eye worm) AGC/PKG protein kinase 0.0025 0.0017 0.0032
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0254 0.0666 0.2502
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0054 0.0133
Echinococcus granulosus rhodopsin orphan GPCR 0.0231 0.0601 0.06
Brugia malayi Thioredoxin reductase 0.1221 0.3414 0.5863
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.018 0.0456 0.1716
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0204 0.0524 0.0556
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0301 0.0801 0.891
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0084 0.0145
Entamoeba histolytica hypothetical protein 0.0096 0.0216 0.2401
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Schistosoma mansoni lipoxygenase 0.0698 0.1926 0.1954
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.018 0.0456 0.0462
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Brugia malayi Nuclear hormone receptor E75 0.0023 0.001 0.0018
Onchocerca volvulus 0.0231 0.0601 0.1507
Brugia malayi 6-phosphofructokinase 0.0222 0.0576 0.099
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0049 0.0084 0.0083
Onchocerca volvulus 0.0159 0.0396 0.0991
Schistosoma mansoni nuclear receptor 0.0023 0.001 0.0009
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0077 0.0076
Echinococcus multilocularis survival motor neuron protein 1 0.1195 0.3339 0.3338
Schistosoma mansoni vesicular amine transporter 0.0082 0.0178 0.0179
Trypanosoma cruzi trypanothione reductase, putative 0.0956 0.2661 0.2829
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0121 0.0122
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0058 0.011 0.0272
Brugia malayi nuclear receptor NHR-67 0.0023 0.001 0.0018
Brugia malayi GnHR receptor homolog 0.0231 0.0601 0.1032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.022 0.0549
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0186 0.0472 0.1381
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0254 0.0666 0.2502
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Echinococcus multilocularis g protein coupled receptor 0.0231 0.0601 0.06
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0054 0.0099 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0075 0.0157 0.0589
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0115 0.0285
Brugia malayi hypothetical protein 0.0159 0.0396 0.0679
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0198 0.0506 0.0505
Brugia malayi Dopamine receptor 0.0231 0.0601 0.1032
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0024 0.0012 0.0035
Loa Loa (eye worm) hypothetical protein 0.0073 0.0152 0.0286
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0037 0.0049 0.0093
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0116 0.0287
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0077 0.0076
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0231 0.0601 0.1032
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0054 0.0099 0.0098
Schistosoma mansoni hypothetical protein 0.0101 0.0233 0.0235
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0036 0.0046 0.0172
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0198 0.0506 0.0512
Mycobacterium ulcerans putative regulatory protein 0.0109 0.0254 0.0955
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Echinococcus multilocularis tumor protein p63 0.1024 0.2853 0.2852
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.022 0.0548
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0046 0.0046
Brugia malayi nuclear receptor RXR 0.0023 0.001 0.0018
Toxoplasma gondii NADPH-glutathione reductase 0.0956 0.2661 0.7793
Loa Loa (eye worm) hypothetical protein 0.06 0.1649 0.3111
Echinococcus granulosus 7TM GPCR rhodopsin 0.0231 0.0601 0.06
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0072 0.0123
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0254 0.0666 0.1666
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0244 0.0637 0.1094
Echinococcus multilocularis nuclear receptor nhr 48 0.0023 0.001 0.0009
Brugia malayi Cytochrome P450 family protein 0.0075 0.0157 0.0269
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0108 0.0114
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Trichomonas vaginalis Heterochromatin protein, putative 0.0035 0.0045 0.0109
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0031 0.0032 0.003
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.006 0.0114 0.0113
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0025 0.0017 0.0016
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0024 0.0012 0.0031
Loa Loa (eye worm) hypothetical protein 0.0198 0.0506 0.0954
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0037 0.0049 0.0085
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.0006 0.0005
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0018 0.0017
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.003 0.0029 0.0085
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0037 0.0049 0.0051
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0956 0.2661 0.2829
Brugia malayi hypothetical protein 0.0035 0.0045 0.0077
Toxoplasma gondii ferredoxin, putative 0.0022 0.0006 0.0014
Brugia malayi MAP kinase sur-1 0.0204 0.0524 0.09
Echinococcus granulosus voltage gated hydrogen channel 1 0.0031 0.0032 0.003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0045 0.0109
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0231 0.0601 0.0609
Loa Loa (eye worm) hypothetical protein 0.0039 0.0054 0.0102
Echinococcus multilocularis glutamate synthase 0.0254 0.0666 0.0664
Brugia malayi follicle stimulating hormone receptor 0.0928 0.2581 0.4432
Plasmodium falciparum ferredoxin, putative 0.0022 0.0006 0.0014
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus multilocularis Immunoglobulin 0.0051 0.0091 0.009
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0143 0.035 0.0875
Schistosoma mansoni adrenodoxin 0.0022 0.0006 0.0005
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0038 0.0053 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1251 0.3498 0.66
Onchocerca volvulus 0.0254 0.0666 0.1668
Schistosoma mansoni lamin 0.0106 0.0247 0.0249
Echinococcus multilocularis roundabout 2 0.0066 0.0131 0.013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trichomonas vaginalis glucosylceramidase, putative 0.077 0.2131 0.5341
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0128 0.0308 0.0902
Schistosoma mansoni calcium-activated potassium channel 0.0031 0.0032 0.0031
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0226 0.0587 0.2205
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0053 0.013
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0098
Loa Loa (eye worm) carboxylesterase 0.0344 0.0921 0.1738
Loa Loa (eye worm) hypothetical protein 0.0052 0.0091 0.0172
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0031 0.0032 0.0032
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0037 0.0049 0.0085
Schistosoma mansoni ap endonuclease 0.0058 0.0108 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0324 0.081
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0075 0.0157 0.0589
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2808 0.7919 0.8422
Echinococcus multilocularis Chromobox protein 3 0.0035 0.0045 0.0044
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0254 0.0666 0.2502
Brugia malayi G-protein coupled receptor 0.0231 0.0601 0.1032
Brugia malayi bZIP transcription factor family protein 0.0338 0.0904 0.1553
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0049 0.0084 0.0145
Trypanosoma cruzi protein kinase A regulatory subunit 0.0024 0.0012 0.0011
Onchocerca volvulus 0.0265 0.0698 0.1749
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0031 0.0032 0.003
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0254 0.0666 0.1666
Schistosoma mansoni glutamate synthase 0.0254 0.0666 0.0675
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0046 0.0048
Schistosoma mansoni apoptosis regulator bax 0.0085 0.0187 0.0189
Echinococcus multilocularis neuropeptide s receptor 0.1158 0.3234 0.3233
Echinococcus granulosus Ankyrin 0.0042 0.0065 0.0063
Plasmodium falciparum thioredoxin reductase 0.1221 0.3414 1
Onchocerca volvulus 0.0058 0.011 0.0275
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0052 0.0128
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0085
Plasmodium vivax ABC transporter G family member 2, putative 0.0036 0.0046 0.013
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0075 0.0157 0.0165
Schistosoma mansoni 60S ribosomal protein L21 0.0044 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0034 0.0041 0.0071
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0075 0.0157 0.0459
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0045 0.0109
Mycobacterium ulcerans hypothetical protein 0.0024 0.0012 0.0044
Schistosoma mansoni adrenodoxin 0.0022 0.0006 0.0005
Schistosoma mansoni inositol monophosphatase 0.0186 0.0472 0.0478
Mycobacterium tuberculosis Possible oxygenase 0.0022 0.0006 0.0017
Schistosoma mansoni hypothetical protein 0.0231 0.0601 0.0609
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0204 0.0524 0.1533
Loa Loa (eye worm) hypothetical protein 0.0054 0.0099 0.0186
Echinococcus multilocularis transient receptor potential cation channel 0.0031 0.0033 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0053 0.0131
Schistosoma mansoni histamine h1 receptor 0.0231 0.0601 0.0609
Schistosoma mansoni hypothetical protein 0.0103 0.0238 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0017 0.0016
Onchocerca volvulus 0.0231 0.0601 0.1507
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0132 0.0318 0.0322
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0045 0.0494
Brugia malayi hypothetical protein 0.0023 0.001 0.0018
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0108 0.0405
Loa Loa (eye worm) hypothetical protein 0.0042 0.0064 0.012
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0254 0.0666 0.7406
Echinococcus granulosus patatin phospholipase domain containing protein 0.0024 0.0012 0.0011
Echinococcus granulosus serotonin receptor 0.0231 0.0601 0.06
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Echinococcus granulosus ATP binding cassette sub family G 0.0036 0.0046 0.0044
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0022 0.0006 0.0017
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0049 0.0084 0.0083
Brugia malayi olfactory channel protein osm-9 0.0031 0.0033 0.0056
Schistosoma mansoni hypothetical protein 0.0026 0.0019 0.0018
Echinococcus multilocularis RUN 0.0159 0.0396 0.0394
Echinococcus granulosus microtubule associated protein 2 0.3487 0.985 0.985
Onchocerca volvulus 0.0222 0.0576 0.1443
Loa Loa (eye worm) hypothetical protein 0.0752 0.2081 0.3926
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0075 0.0157 0.0589
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0025 0.0017 0.0016
Brugia malayi hypothetical protein 0.0023 0.001 0.0018
Brugia malayi Carboxylesterase family protein 0.0058 0.011 0.0188
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0049 0.0084 0.0084
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0084 0.0083
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0254 0.0666 0.1666
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Brugia malayi steroid hormone receptor 0.0049 0.0084 0.0145
Schistosoma mansoni neuropeptide f receptor 76f 0.0231 0.0601 0.0609
Echinococcus granulosus 7tm_1 domain containing protein 0.0231 0.0601 0.06
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0037 0.0049 0.0141
Schistosoma mansoni hypothetical protein 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0101 0.0231 0.0435
Echinococcus multilocularis lamin dm0 0.0106 0.0247 0.0246
Leishmania major NADH dehydrogenase, putative 0.0254 0.0666 0.0707
Loa Loa (eye worm) helicase 0.0035 0.0045 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.022 0.0549
Echinococcus multilocularis transcription factor Dp 1 0.0076 0.0161 0.016
Loa Loa (eye worm) hypothetical protein 0.0108 0.0253 0.0477
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0132 0.0318 0.0337
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0108 0.0253 0.0255
Loa Loa (eye worm) hypothetical protein 0.0074 0.0155 0.0292
Echinococcus multilocularis serotonin receptor 0.06 0.1649 0.1648
Schistosoma mansoni hypothetical protein 0.0231 0.0601 0.0609
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0042 0.0063 0.0154
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0006 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0057 0.0107 0.0184
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0108 0.0204
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0024 0.0012 0.0027
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0254 0.0666 0.0664
Trichomonas vaginalis glucosylceramidase, putative 0.0505 0.1379 0.3456
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0166 0.0417 0.1222
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0024 0.0012 0.0011
Brugia malayi Carboxylesterase family protein 0.0344 0.0921 0.1582
Trypanosoma brucei protein kinase, putative 0.0204 0.0524 0.0556
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0132 0.0318 0.0547
Trypanosoma cruzi cAMP response protein 1, putative 0.0024 0.0012 0.0011
Brugia malayi Carboxylesterase family protein 0.0344 0.0921 0.1582
Brugia malayi cytochrome P450 0.0075 0.0157 0.0269
Trypanosoma brucei C-8 sterol isomerase, putative 0.1471 0.4124 0.4386
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0249 0.0623
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0063 0.0124 0.0311
Treponema pallidum catabolite gene activator (Crp) 0.0024 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0058 0.0111 0.0209
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0956 0.2661 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0231 0.0601 0.06
Trichomonas vaginalis glucosylceramidase, putative 0.0505 0.1379 0.3456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.022 0.0548
Echinococcus multilocularis short transient receptor potential channel 6 0.0031 0.0032 0.003
Mycobacterium ulcerans ferredoxin reductase 0.0254 0.0666 0.2502
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0004 0.0007
Onchocerca volvulus 0.0058 0.011 0.0275
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0254 0.0666 0.0664
Mycobacterium tuberculosis Conserved protein 0.0024 0.0012 0.0035
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0075 0.0157 0.0589
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Brugia malayi Cytochrome P450 family protein 0.0101 0.0232 0.0398
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0231 0.0601 0.1507
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0036 0.0046 0.0045
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0477
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0254 0.0666 0.2059
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.018 0.0455 0.5059
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0034 0.0041 0.0041
Echinococcus multilocularis G protein coupled receptor 139 0.0231 0.0601 0.06
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0928 0.2581 0.4869
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0054 0.0099 0.0249
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0031 0.0032 0.0054
Echinococcus granulosus transient receptor potential gamma protein 0.0031 0.0032 0.003
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0022 0.0006 0.0005
Entamoeba histolytica thioredoxin reductase, putative 0.0254 0.0666 0.7406
Trichomonas vaginalis 6-phosphofructokinase, putative 0.006 0.0115 0.0285
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Echinococcus granulosus tumor protein p63 0.1024 0.2853 0.2852
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.001 0.0009
Schistosoma mansoni disulfide oxidoreductase 0.0254 0.0666 0.0675
Echinococcus multilocularis microtubule associated protein 2 0.3487 0.985 0.985
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0114 0.0114
Trichomonas vaginalis aldehyde oxidase, putative 0.067 0.1846 0.4627
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0049 0.0084 0.0159
Trypanosoma cruzi trypanothione reductase, putative 0.1221 0.3414 0.363
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0019 0.0045
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0078 0.0077
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0254 0.0666 0.7406
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0231 0.0601 0.0609
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0075 0.0157 0.0589
Loa Loa (eye worm) hypothetical protein 0.0639 0.176 0.332
Echinococcus multilocularis tyrosine protein kinase HCK 0.0039 0.0055 0.0054
Echinococcus granulosus histone lysine methyltransferase setb 0.0198 0.0506 0.0505
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.0041 0.004
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0024 0.0012 0.0011
Onchocerca volvulus 0.0231 0.0601 0.1507
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0045 0.0128
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0536 0.1467 0.1489
Brugia malayi nuclear receptor NHR-88 0.0023 0.001 0.0018
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0254 0.0666 0.1947
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0254 0.0666 0.1947
Toxoplasma gondii target of rapamycin (TOR), putative 0.0134 0.0324 0.0946
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0698 0.1926 0.1925
Schistosoma mansoni nuclear hormone receptor 0.0023 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0047 0.0078 0.0147
Echinococcus multilocularis short transient receptor potential channel 6 0.0031 0.0033 0.0031
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.006 0.0115 0.0428
Giardia lamblia NADH oxidase lateral transfer candidate 0.0956 0.2661 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143 0.035 0.0876
Schistosoma mansoni neuropeptide receptor 0.0231 0.0601 0.0609
Entamoeba histolytica hypothetical protein 0.0035 0.0045 0.0496
Chlamydia trachomatis DNA gyrase subunit B 0.0039 0.0054 0.0199
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0045 0.0044
Echinococcus multilocularis neuropeptides capa receptor 0.0231 0.0601 0.06
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0031 0.0032 0.0031
Echinococcus granulosus neuroligin 0.0058 0.011 0.0108
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0254 0.0666 0.0707
Loa Loa (eye worm) TK protein kinase 0.0039 0.0055 0.0104
Echinococcus multilocularis orexin receptor type 2 0.0231 0.0601 0.06
Mycobacterium ulcerans hypothetical protein 0.0024 0.0012 0.0044
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0074 0.0155 0.0454
Toxoplasma gondii Erv1 / Alr family protein 0.007 0.0142 0.0414
Brugia malayi putative neuropeptide receptor NPR1 0.0231 0.0601 0.1032
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0222 0.0575 0.0611
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Echinococcus granulosus orexin receptor type 2 0.0231 0.0601 0.06
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0024 0.0012 0.0011
Echinococcus granulosus neuropeptide receptor 0.0231 0.0601 0.06
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0001 0.0002
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.006 0.0116 0.0115
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0036 0.0046 0.0047
Schistosoma mansoni biogenic amine receptor 0.0231 0.0601 0.0609
Onchocerca volvulus 0.0106 0.0247 0.0619
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0639 0.176 0.3022
Schistosoma mansoni neuroligin 3 (S09 family) 0.0058 0.011 0.011
Brugia malayi protein-tyrosine kinase 0.0043 0.0066 0.0113
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.007 0.0142 0.015
Schistosoma mansoni ABC transporter 0.003 0.003 0.003
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0231 0.0601 0.1032
Echinococcus multilocularis sodium and chloride dependent glycine 0.0108 0.0253 0.0252
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0956 0.2661 0.7793
Brugia malayi Cytochrome P450 family protein 0.0101 0.0232 0.0398
Schistosoma mansoni hypothetical protein 0.0047 0.0078 0.0078
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0051 0.0091 0.0172
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0254 0.0666 0.195
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0455 0.1238 0.3627
Echinococcus granulosus hypothetical protein 0.0031 0.0032 0.003
Mycobacterium ulcerans regulatory protein 0.0024 0.0012 0.0044
Schistosoma mansoni voltage-gated potassium channel 0.0068 0.0138 0.0138
Echinococcus granulosus ferredoxin 0.0022 0.0006 0.0005
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0231 0.0244
Echinococcus multilocularis para nitrobenzyl esterase 0.0058 0.011 0.0108
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0024 0.0012 0.0011
Brugia malayi chromobox protein homolog 3 0.0063 0.0124 0.0213
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0015 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0324 0.081
Echinococcus granulosus carboxylesterase 5A 0.0344 0.0921 0.092
Echinococcus granulosus Chromo domain 0.0035 0.0045 0.0044
Echinococcus granulosus cGMP dependent protein kinase 0.0025 0.0017 0.0016
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0254 0.0666 0.0707
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.001 0.0009
Onchocerca volvulus 0.0231 0.0601 0.1507
Loa Loa (eye worm) DR-78 0.0023 0.001 0.002
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0338 0.0904 0.0903
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0024 0.0012 0.0027
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0075 0.0157 0.0589
Echinococcus granulosus rhodopsin orphan GPCR 0.0231 0.0601 0.06
Brugia malayi intermediate filament protein 0.0106 0.0247 0.0424
Brugia malayi Cytochrome P450 family protein 0.017 0.0428 0.0736
Brugia malayi Serotonin receptor 0.0231 0.0601 0.1032
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0001 0.0005
Brugia malayi FAT domain containing protein 0.0026 0.0019 0.0033
Echinococcus granulosus biogenic amine 5HT receptor 0.06 0.1649 0.1648
Echinococcus granulosus shaker cognate 0.0031 0.0032 0.003
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0231 0.0601 0.0609
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0084 0.0084
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0254 0.0666 0.2502
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0046 0.0077 0.0076
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.03 0.0875
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0085 0.0187 0.0322
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0121 0.0229
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0046 0.0077 0.0076
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0042 0.0064 0.012
Echinococcus multilocularis transfer RNA-Lys 0.0109 0.0254 0.0253
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0045 0.0073 0.0072
Loa Loa (eye worm) hypothetical protein 0.0206 0.0529 0.0998
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.007 0.0142 0.0414
Plasmodium falciparum cGMP-dependent protein kinase 0.0025 0.0017 0.0046
Trypanosoma brucei NADH dehydrogenase 0.0254 0.0666 0.0707
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0254 0.0666 0.2059
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0132 0.0318 0.0317
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0121 0.0122
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0254 0.0666 0.0707
Brugia malayi 6-phosphofructokinase 0.0222 0.0575 0.0988
Onchocerca volvulus 0.0038 0.0053 0.0134
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0254 0.0666 0.195
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0956 0.2661 0.2829
Schistosoma mansoni acetylcholinesterase 0.0058 0.011 0.011
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0186 0.0472 0.0501
Loa Loa (eye worm) cytochrome P450 family protein 0.0101 0.0232 0.0438
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Loa Loa (eye worm) hypothetical protein 0.0223 0.0577 0.1088
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Loa Loa (eye worm) TK protein kinase 0.0043 0.0066 0.0124
Echinococcus multilocularis lipoxygenase domain containing protein 0.0159 0.0396 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0053 0.0131
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0031 0.0032 0.003
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0114 0.0112
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0012 0.0011
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0698 0.1926 0.1925
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0132 0.0318 0.0337
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus granulosus Immunoglobulin 0.0051 0.0091 0.009
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0121 0.0208
Treponema pallidum hypothetical protein 0.0109 0.0254 0.0953
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0037 0.0049 0.0049
Brugia malayi RE15519p 0.0231 0.0601 0.1032
Echinococcus granulosus bloom syndrome protein 0.0021 0.0004 0.0003
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.018 0.0455 0.0781
Brugia malayi phosphofructokinase 0.0222 0.0575 0.0988
Schistosoma mansoni hypothetical protein 0.0021 0.0005 0.0004
Mycobacterium leprae Conserved hypothetical protein 0.0075 0.0157 0.0484
Trypanosoma brucei cAMP response protein 1, putative 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0204 0.0524 0.0556
Echinococcus granulosus voltage dependent calcium channel 0.0031 0.0032 0.003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0198 0.0506 0.0512
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0231 0.0601 0.1134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0041 0.01
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0054 0.0099 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0049 0.0084 0.0145
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0041 0.01
Schistosoma mansoni hypothetical protein 0.0855 0.2373 0.2409
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.03 0.0879
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0084 0.0145
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus granulosus tyrosine protein kinase Lyn 0.0048 0.0082 0.0081
Giardia lamblia DNA repair protein RAD52 0.0336 0.0899 0.3374
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0022 0.0006 0.0017
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0077 0.0076
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0074 0.0155 0.0479
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0051 0.009 0.0089
Toxoplasma gondii transporter, cation channel family protein 0.0031 0.0032 0.0089
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0524 0.1312
Echinococcus granulosus rhodopsin orphan GPCR 0.0231 0.0601 0.06
Leishmania major regulatory subunit of protein kinase a-like protein 0.0024 0.0012 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0075 0.0157 0.0459
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0231 0.0601 0.1134
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0254 0.0666 0.7406
Mycobacterium ulcerans glutamate synthase subunit beta 0.0254 0.0666 0.2502
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0035 0.0045 0.0128
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0045 0.0044
Trichomonas vaginalis Ferredoxin 2 0.0022 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0036 0.0046 0.0087
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0072 0.0072
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0075 0.0157 0.0459
Loa Loa (eye worm) voltage-gated calcium channel 0.0031 0.0032 0.006
Onchocerca volvulus 0.0231 0.0601 0.1507
Onchocerca volvulus 0.0231 0.0601 0.1507
Onchocerca volvulus 0.0024 0.0012 0.003
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0956 0.2661 0.7793
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0031 0.0032 0.0031
Leishmania major trypanothione reductase 0.1221 0.3414 0.363
Brugia malayi Cyclic-nucleotide gated cation channel 0.0054 0.0099 0.017
Toxoplasma gondii transporter, cation channel family protein 0.0031 0.0032 0.0089
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0132 0.0318 0.06
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0049 0.0084 0.0083
Brugia malayi neuropeptide F receptor 0.0231 0.0601 0.1032
Schistosoma mansoni sodium/chloride dependent transporter 0.0108 0.0253 0.0255
Schistosoma mansoni opsin-like receptor 0.0231 0.0601 0.0609
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0143 0.0351 0.0372
Treponema pallidum cyclic nucleotide binding protein 0.0024 0.0012 0.0043
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0026 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0956 0.2661 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0046 0.0045
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0108 0.0317
Brugia malayi Blistered cuticle protein 3 0.0146 0.036 0.0619
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus multilocularis potassium large conductance calcium activated 0.0031 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0159 0.0396 0.0746
Treponema pallidum quinoline 2-oxidoreductase 0.0106 0.0247 0.0926
Mycobacterium tuberculosis Conserved hypothetical protein 0.0024 0.0012 0.0035
Leishmania major cytochrome p450-like protein 0.0101 0.0232 0.0245
Schistosoma mansoni hypothetical protein 0.0254 0.0666 0.0675
Echinococcus multilocularis hyperpolarization activated cyclic 0.0054 0.0099 0.0098
Schistosoma mansoni fkbp-rapamycin associated protein 0.0034 0.0041 0.0041
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0035 0.0045 0.0128
Loa Loa (eye worm) heterochromatin protein 1 0.0094 0.0212 0.04
Onchocerca volvulus 0.0231 0.0601 0.1507
Trichomonas vaginalis phosphofructokinase, putative 0.0222 0.0575 0.144
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.03 0.1127
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0254 0.0666 0.7406
Loa Loa (eye worm) phosphatidylinositol 3 0.006 0.0116 0.0218
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0316 0.0841 0.3162
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0108 0.0268
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0254 0.0666 0.2502
Schistosoma mansoni hypothetical protein 0.0047 0.0078 0.0078
Echinococcus granulosus short transient receptor potential channel 6 0.0031 0.0033 0.0031
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0231 0.0601 0.06
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0101 0.0232 0.0872
Echinococcus granulosus inositol monophosphatase 1 0.0186 0.0472 0.0471
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0031 0.0032 0.003
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0075 0.0157 0.0589
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0078 0.0167 0.0287
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0046 0.0113
Schistosoma mansoni hypothetical protein 0.0047 0.0078 0.0078
Brugia malayi hypothetical protein 0.0494 0.1347 0.2313
Echinococcus granulosus ATP binding cassette sub family G 0.0036 0.0046 0.0044
Onchocerca volvulus 0.0058 0.011 0.0275
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0254 0.0666 0.1666
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.03 0.1127
Treponema pallidum fructose-bisphosphate aldolase 0.0301 0.0801 0.3008
Echinococcus multilocularis mitogen activated protein kinase 3 0.0204 0.0524 0.0523
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0072 0.007
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0108 0.12
Loa Loa (eye worm) hypothetical protein 0.0464 0.1264 0.2385
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0031 0.0032 0.0054
Trichomonas vaginalis phosphofructokinase, putative 0.0222 0.0575 0.144
Trichomonas vaginalis glucosylceramidase, putative 0.077 0.2131 0.5341
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0215 0.0556 0.0563
Onchocerca volvulus 0.0022 0.0006 0.0015
Echinococcus multilocularis sodium channel protein 0.0241 0.0629 0.0628
Echinococcus granulosus mitogen activated protein kinase 3 0.0204 0.0524 0.0523
Loa Loa (eye worm) hypothetical protein 0.0051 0.0091 0.0172
Onchocerca volvulus Neuropeptide F receptor homolog 0.0231 0.0601 0.1507
Brugia malayi Pre-SET motif family protein 0.1251 0.3498 0.6008
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.0366 0.0691
Echinococcus multilocularis Protein lozenge 0.0058 0.011 0.0109
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0034 0.0041 0.0042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2808 0.7919 0.8422
Brugia malayi TAR-binding protein 0.0062 0.0121 0.0208
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0075 0.0157 0.0459
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0046 0.0048
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0023 0.001 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.018 0.0455 0.1137
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0049 0.0084 0.0145
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0002
Toxoplasma gondii hypothetical protein 0.0108 0.0253 0.0737
Loa Loa (eye worm) hypothetical protein 0.0042 0.0064 0.0121
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0035
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0024 0.0012 0.0011
Echinococcus multilocularis 6 phosphofructokinase 0.0222 0.0575 0.0574
Trypanosoma cruzi cytochrome P450, putative 0.0101 0.0232 0.0245
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0737
Schistosoma mansoni sodium/chloride dependent transporter 0.0639 0.176 0.1785
Loa Loa (eye worm) inositol-1 0.0186 0.0472 0.0891
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0054 0.0099 0.0098
Onchocerca volvulus 0.0058 0.011 0.0275
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0254 0.0666 0.0707
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0049 0.0084 0.0145
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0051 0.0091 0.009
Echinococcus multilocularis voltage gated potassium channel 0.0031 0.0032 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.022 0.0549
Echinococcus granulosus potassium voltage gated channel protein 0.0031 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.1886 0.5301 1
Schistosoma mansoni chromobox protein 0.0035 0.0045 0.0044
Echinococcus granulosus cpg binding protein 0.0031 0.0034 0.0032
Schistosoma mansoni transient receptor potential channel 0.0031 0.0033 0.0032
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0075 0.0157 0.0589
Toxoplasma gondii hypothetical protein 0.0031 0.0032 0.0089
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0024 0.0012 0.0011
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.0006 0.0005
Echinococcus granulosus ryanodine receptor 44f 0.0031 0.0032 0.003
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0075 0.0157 0.0459
Loa Loa (eye worm) thioredoxin reductase 0.1221 0.3414 0.644
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0017 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Mycobacterium tuberculosis Carboxylesterase LipT 0.0058 0.011 0.0321
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0078 0.0134
Echinococcus multilocularis expressed conserved protein 0.0025 0.0017 0.0016
Echinococcus granulosus rhodopsin orphan GPCR 0.0231 0.0601 0.06
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0956 0.2661 0.7793
Echinococcus granulosus contactin 0.0025 0.0015 0.0013
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0045 0.0128
Entamoeba histolytica hypothetical protein 0.0034 0.0041 0.0454
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0063 0.0154
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0024 0.0012 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0049 0.0084 0.0145
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.03 0.1127
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0173 0.0435 0.0434
Plasmodium falciparum glutathione reductase 0.1221 0.3414 1
Echinococcus multilocularis transient receptor potential cation channel 0.0031 0.0033 0.0031
Echinococcus multilocularis serotonin receptor 0.06 0.1649 0.1648
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0077 0.0076
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1158 0.3233 0.947
Brugia malayi Augmenter of liver regeneration 0.007 0.0142 0.0245
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0017 0.0016
Brugia malayi ORL1-like opioid receptor 0.0231 0.0601 0.1032
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0057 0.0107 0.0203
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.333 0.9402 1
Mycobacterium leprae putative cytochrome p450 0.0075 0.0157 0.0484
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0001 0.0004
Schistosoma mansoni neuropeptide receptor 0.0231 0.0601 0.0609
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0031 0.0032 0.003
Onchocerca volvulus 0.015 0.037 0.0928
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0068 0.0138 0.0236
Brugia malayi Carboxylesterase family protein 0.0058 0.011 0.0188
Schistosoma mansoni biogenic amine (5HT) receptor 0.0595 0.1634 0.1658
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0031 0.0032 0.0054
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1175 0.3283 0.3282
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0031 0.0032 0.0031
Leishmania major hypothetical protein, conserved 0.007 0.0142 0.015
Schistosoma mansoni opsin-like receptor 0.0231 0.0601 0.0609
Echinococcus granulosus neuropeptides capa receptor 0.0231 0.0601 0.06
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0038 0.0053 0.0131
Brugia malayi conserved hypotetical protein 0.0023 0.001 0.0018
Echinococcus granulosus alpha 1A adrenergic receptor 0.0231 0.0601 0.06
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0222 0.0575 0.0611
Leishmania major hypothetical protein, conserved 0.0101 0.0231 0.0244
Echinococcus granulosus sex peptide receptor 0.0231 0.0601 0.06
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0186 0.0472 0.1181
Brugia malayi sulfakinin receptor protein 0.0231 0.0601 0.1032
Leishmania major hypothetical protein, conserved 0.0022 0.0006 0.0005
Onchocerca volvulus Bile acid receptor homolog 0.0049 0.0084 0.0211
Echinococcus multilocularis transient receptor potential cation channel 0.0031 0.0032 0.003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0084 0.0145
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0241 0.0629 0.0668
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0049 0.0084 0.0084
Schistosoma mansoni RAR-like nuclear receptor 0.0049 0.0084 0.0084
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0024 0.0012 0.004
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.018 0.0455 0.0482
Loa Loa (eye worm) hypothetical protein 0.0038 0.0053 0.0101
Schistosoma mansoni glutaminase 0.0267 0.0704 0.0713
Loa Loa (eye worm) hypothetical protein 0.0108 0.0253 0.0477
Plasmodium vivax hypothetical protein, conserved 0.0108 0.0253 0.0737
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Echinococcus granulosus transcription factor Dp 1 0.0076 0.0161 0.016
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0524 0.1312
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0231 0.0673
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0161 0.0401 0.0757
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0008 0.0007
Echinococcus multilocularis fmrfamide receptor 0.0231 0.0601 0.06
Mycobacterium ulcerans DNA gyrase subunit B 0.002 0.0001 0.0005
Trichomonas vaginalis Ferredoxin 7 0.0022 0.0006 0.0012
Echinococcus granulosus sodium leak channel non selective protein 0.0031 0.0032 0.003
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.018 0.0456 0.0455
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0108 0.0268
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.0366 0.0629
Echinococcus granulosus neuropeptide Y receptor 0.0231 0.0601 0.06
Brugia malayi glutaminase DH11.1 0.0267 0.0704 0.1209
Loa Loa (eye worm) hypothetical protein 0.0034 0.0041 0.0078
Schistosoma mansoni voltage-gated ion channel 0.0031 0.0032 0.0031
Schistosoma mansoni hypothetical protein 0.0045 0.0073 0.0073
Trypanosoma cruzi DNA topoisomerase II, putative 0.0078 0.0167 0.0177
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0116 0.0287
Echinococcus granulosus calcium activated potassium channel 0.0032 0.0037 0.0036
Trypanosoma brucei ABC transporter, putative 0.0036 0.0046 0.0047
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0075 0.0157 0.0165
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.0006 0.0005
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0075 0.0157 0.0165
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0254 0.0666 0.2498
Echinococcus granulosus thioredoxin glutathione reductase 0.1221 0.3414 0.3413
Brugia malayi Bromodomain containing protein 0.0079 0.0169 0.029
Echinococcus granulosus tyrosine protein kinase Src42A 0.0046 0.0077 0.0076
Entamoeba histolytica phosphofructokinase, putative 0.0222 0.0575 0.64
Echinococcus multilocularis FTZ F1 alpha 0.0049 0.0084 0.0083
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0108 0.0186
Leishmania major hypothetical protein, conserved 0.0024 0.0012 0.0011
Brugia malayi tailless protein 0.0023 0.001 0.0018
Schistosoma mansoni hypothetical protein 0.0085 0.0187 0.0189
Brugia malayi hypothetical protein 0.0101 0.0231 0.0396
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0114 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0008 0.0018
Trypanosoma brucei protein kinase A regulatory subunit 0.0024 0.0012 0.0011
Brugia malayi Pre-SET motif family protein 0.018 0.0456 0.0783
Schistosoma mansoni nuclear receptor 0.0023 0.001 0.0009
Loa Loa (eye worm) melatonin receptor type 1A 0.0231 0.0601 0.1134
Schistosoma mansoni amine GPCR 0.0231 0.0601 0.0609
Trichomonas vaginalis Ferredoxin 4 0.0022 0.0006 0.0012
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0344 0.0921 0.0934
Leishmania major hypothetical protein, conserved 0.0254 0.0666 0.0707
Loa Loa (eye worm) glutaminase 0.0267 0.0704 0.1328
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0231 0.0601 0.1134
Mycobacterium ulcerans glutaminase 0.0267 0.0704 0.2645
Loa Loa (eye worm) neuropeptide F receptor 0.0231 0.0601 0.1134
Trichomonas vaginalis glucosylceramidase, putative 0.0532 0.1457 0.3649
Echinococcus multilocularis carboxylesterase 5A 0.0344 0.0921 0.092
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0072 0.0072
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0023 0.0044
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0096 0.0216 0.2401
Plasmodium vivax glutathione reductase, putative 0.1221 0.3414 1
Giardia lamblia ABC transporter 0.0035 0.0044 0.0163
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0084 0.0083
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0072 0.0135
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0204 0.0524 0.0556
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0022 0.0006 0.0014
Schistosoma mansoni hypothetical protein 0.0231 0.0601 0.0609
Trichomonas vaginalis PIKK family atypical protein kinase 0.0106 0.0246 0.0615
Trichomonas vaginalis PIKK family atypical protein kinase 0.012 0.0287 0.0716
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1158 0.3233 1
Echinococcus granulosus hypothetical protein 0.2989 0.8434 0.8433
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.0036
Schistosoma mansoni cpg binding protein 0.0031 0.0034 0.0033
Brugia malayi ABC transporter family protein 0.003 0.003 0.0052
Schistosoma mansoni retinoic acid receptor RXR 0.0049 0.0084 0.0084
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0001 0.0005
Echinococcus granulosus two pore calcium channel protein 2 0.0031 0.0032 0.003
Echinococcus multilocularis neuropeptide Y receptor 0.0231 0.0601 0.06
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0147 0.0363 0.1063
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0207
Schistosoma mansoni netrin receptor unc5 0.005 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0035
Treponema pallidum sodium- and chloride- dependent transporter 0.0639 0.176 0.6613
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0956 0.2661 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0045 0.0073 0.0072
Brugia malayi Egg laying defective protein 4 0.0025 0.0017 0.0029
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0037 0.0049 0.0141
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0254 0.0666 0.1666
Loa Loa (eye worm) RNA binding protein 0.0062 0.0121 0.0229
Schistosoma mansoni hypothetical protein 0.003 0.0029 0.0028
Toxoplasma gondii ferodoxin FD 0.0022 0.0006 0.0014
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0026 0.0018 0.0035
Mycobacterium ulcerans transcriptional regulatory protein 0.0024 0.0012 0.0044
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0075 0.0157 0.0589
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0085
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0031 0.0032 0.003
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0046 0.0077 0.0076
Echinococcus granulosus netrin receptor unc 5 0.005 0.0087 0.0086
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0524 0.1312
Mycobacterium ulcerans transmembrane transport protein 0.0024 0.0012 0.0044
Brugia malayi nuclear receptor NHR-88 0.0049 0.0084 0.0145
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0075 0.0157 0.0459
Brugia malayi Transient-receptor-potential like protein 0.0031 0.0032 0.0054
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0022 0.0006 0.0014
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0038 0.0053 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0121 0.0122
Echinococcus multilocularis transient receptor potential cation channel 0.0031 0.0032 0.003
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0147 0.0363 0.1122
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0063 0.0154
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0254 0.0666 0.0707
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Loa Loa (eye worm) hypothetical protein 0.0046 0.0074 0.014
Schistosoma mansoni hypothetical protein 0.0042 0.0064 0.0063
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0049 0.0084 0.0084

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) 0 Reduction in cartilage destruction in mouse CIA model BID for 14 days ChEMBL. 18242992
Activity (functional) = 35 % Reduction in progression of collagen-induced arthritis scores in mouse CIA model at 5 mg/kg, po bid ChEMBL. 18242992
Activity (functional) = 35 % Reduction in progression of collagen-induced arthritis scores in mouse CIA model at 5 mg/kg, po bid ChEMBL. 18242992
Activity (functional) = 65 % Reduction in progression of collagen-induced arthritis scores in mouse CIA model at 30 mg/kg, po bid ChEMBL. 18242992
Activity (functional) = 65 % Reduction in progression of collagen-induced arthritis scores in mouse CIA model at 30 mg/kg, po bid ChEMBL. 18242992
Activity (functional) = 80 % Reduction in pannus formation in mouse CIA model BID for 14 days ChEMBL. 18242992
Activity (functional) = 80 % Reduction in bone destruction in mouse CIA model BID for 14 days ChEMBL. 18242992
Activity (functional) = 80 % Reduction in pannus formation in mouse CIA model BID for 14 days ChEMBL. 18242992
Activity (functional) = 80 % Reduction in bone destruction in mouse CIA model BID for 14 days ChEMBL. 18242992
Cmax (ADMET) = 853 ng/ml Cmax in CD1 mouse at 2 mg/kg, iv and 10 mg/kg, po ChEMBL. 18242992
Cmax (ADMET) = 853 ng/ml Cmax in CD1 mouse at 2 mg/kg, iv and 10 mg/kg, po ChEMBL. 18242992
F (ADMET) = 45 % Oral bioavailability in CD1 mouse at 10 mg/kg ChEMBL. 18242992
F (ADMET) = 45 % Oral bioavailability in CD1 mouse at 10 mg/kg ChEMBL. 18242992
IC50 (binding) = 6.4 nM Inhibition of AXL kinase ChEMBL. 22247788
IC50 (binding) = 0.00078 uM Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarization ChEMBL. 18242992
IC50 (binding) = 0.00078 uM Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarization ChEMBL. 18242992
IC50 (binding) = 0.0008 uM Inhibition of FMS (unknown origin) ChEMBL. 18495479
IC50 (binding) = 0.0008 uM Inhibition of FMS (unknown origin) ChEMBL. 18495479
IC50 (binding) = 0.0008 uM Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarization ChEMBL. 22039836
IC50 (ADMET) = 0.002 uM Antiproliferative activity against BMDM cells (unknown origin) ChEMBL. 18495479
IC50 (binding) = 0.0035 uM Inhibition of Kit (unknown origin) after 30 mins by fluorescence polarization ChEMBL. 18242992
IC50 (binding) = 0.0035 uM Inhibition of Kit (unknown origin) after 30 mins by fluorescence polarization ChEMBL. 18242992
IC50 (binding) = 0.0064 uM Inhibition of Axl (unknown origin) after 11 mins by fluorescence polarization ChEMBL. 18242992
IC50 (binding) = 0.0064 uM Inhibition of Axl (unknown origin) after 11 mins by fluorescence polarization ChEMBL. 18242992
IC50 (binding) = 0.011 uM Inhibition of TrkA (unknown origin) after 27 mins by fluorescence polarization ChEMBL. 18242992
IC50 (binding) = 0.011 uM Inhibition of TrkA (unknown origin) after 27 mins by fluorescence polarization ChEMBL. 18242992
IC50 (binding) = 0.018 uM Inhibition of Flt3 (unknown origin) after 25 mins by fluorescence polarization ChEMBL. 18242992
IC50 (binding) = 0.018 uM Inhibition of Flt3 (unknown origin) after 25 mins by fluorescence polarization ChEMBL. 18242992
IC50 (binding) = 0.083 uM Inhibition of IRKbeta (unknown origin) after 20 mins by fluorescence polarization ChEMBL. 18242992
t1/2 (ADMET) = 244 min Half life in CD1 mouse at 2 mg/kg, iv and 10 mg/kg, po ChEMBL. 18242992
T1/2 (ADMET) = 244 min Half life in CD1 mouse at 2 mg/kg, iv and 10 mg/kg, po ChEMBL. 18242992
Vdss (ADMET) = 5635 ml/kg Volume of distribution in CD1 mouse at 2 mg/kg, iv and 10 mg/kg, po ChEMBL. 18242992
Vdss (ADMET) = 5635 ml/kg Volume of distribution in CD1 mouse at 2 mg/kg, iv and 10 mg/kg, po ChEMBL. 18242992

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

4 literature references were collected for this gene.

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