Detailed information for compound 506613

Basic information

Technical information
  • TDR Targets ID: 506613
  • Name: 4-cyano-N-[2-(4-methylpiperidin-1-yl)-4-piper azin-1-ylphenyl]-1H-pyrrole-2-carboxamide
  • MW: 392.497 | Formula: C22H28N6O
  • H donors: 3 H acceptors: 2 LogP: 2.47 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1c[nH]c(c1)C(=O)Nc1ccc(cc1N1CCC(CC1)C)N1CCNCC1
  • InChi: 1S/C22H28N6O/c1-16-4-8-28(9-5-16)21-13-18(27-10-6-24-7-11-27)2-3-19(21)26-22(29)20-12-17(14-23)15-25-20/h2-3,12-13,15-16,24-25H,4-11H2,1H3,(H,26,29)
  • InChiKey: YPPDZAOVZSJMKT-UHFFFAOYSA-N  

Network

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Synonyms

  • 4-cyano-N-[2-(4-methyl-1-piperidyl)-4-piperazin-1-yl-phenyl]-1H-pyrrole-2-carboxamide
  • 4-cyano-N-[2-(4-methyl-1-piperidinyl)-4-(1-piperazinyl)phenyl]-1H-pyrrole-2-carboxamide
  • 4-cyano-N-[2-(4-methylpiperidin-1-yl)-4-piperazin-1-yl-phenyl]-1H-pyrrole-2-carboxamide
  • 4-cyano-N-[2-(4-methylpiperidino)-4-piperazino-phenyl]-1H-pyrrole-2-carboxamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens colony stimulating factor 1 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus macrophage colony stimulating factor 1 receptor Get druggable targets OG5_132967 All targets in OG5_132967

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0104 0.0241 0.0455
Chlamydia trachomatis DNA gyrase subunit B 0.0039 0.0054 0.0199
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0231 0.0601 0.0609
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Schistosoma mansoni neuropeptide F-like receptor 0.0231 0.0601 0.0609
Echinococcus granulosus intermediate filament protein 0.0106 0.0247 0.0246
Brugia malayi Augmenter of liver regeneration 0.007 0.0142 0.0245
Echinococcus granulosus ATP binding cassette sub family G 0.0036 0.0046 0.0044
Plasmodium falciparum glutathione reductase 0.0956 0.2661 0.7793
Plasmodium vivax ABC transporter G family member 2, putative 0.0036 0.0046 0.013
Schistosoma mansoni biogenic amine receptor 0.0231 0.0601 0.0609
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.03 0.0879
Leishmania major hypothetical protein, unknown function 0.0031 0.0032 0.0032
Giardia lamblia DNA repair protein RAD52 0.0336 0.0899 0.3374
Loa Loa (eye worm) hypothetical protein 0.0344 0.0921 0.1738
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Loa Loa (eye worm) hypothetical protein 0.1886 0.5301 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0054 0.0099 0.0245
Echinococcus granulosus rhodopsin orphan GPCR 0.0231 0.0601 0.06
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.004 0.0059 0.0061
Onchocerca volvulus 0.0024 0.0012 0.003
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0254 0.0666 0.7406
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0084 0.0145
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0147 0.0363 0.1063
Loa Loa (eye worm) hypothetical protein 0.0036 0.0046 0.0087
Loa Loa (eye worm) glutathione reductase 0.1221 0.3414 0.644
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0066 0.0133 0.0333
Brugia malayi jmjC domain containing protein 0.0059 0.0114 0.0195
Echinococcus granulosus 7tm_1 domain containing protein 0.0231 0.0601 0.06
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0143 0.035 0.0875
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0031 0.0032 0.003
Brugia malayi Valyl-tRNA synthetase 0.0035 0.0045 0.0077
Echinococcus multilocularis cpg binding protein 0.0031 0.0034 0.0032
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0024 0.0012 0.0011
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0031 0.0032 0.0054
Echinococcus granulosus cytochrome P450 2K1 0.0075 0.0157 0.0155
Mycobacterium ulcerans oxygenase 0.0022 0.0006 0.0022
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0025 0.0017 0.0016
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0301 0.0801 0.891
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0024 0.0012 0.0011
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0031 0.0032 0.0054
Trichomonas vaginalis set domain proteins, putative 0.1424 0.3989 1
Plasmodium vivax amine transporter, putative 0.0108 0.0253 0.0737
Brugia malayi SRC-1 0.0046 0.0077 0.0132
Onchocerca volvulus 0.0231 0.0601 0.1507
Schistosoma mansoni hypothetical protein 0.0855 0.2373 0.2409
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0166 0.0417 0.1222
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0008 0.0007
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0204 0.0524 0.1533
Loa Loa (eye worm) cytochrome P450 family protein 0.0101 0.0232 0.0438
Loa Loa (eye worm) glutaminase 2 0.0267 0.0704 0.1328
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.004 0.0059 0.0061
Echinococcus granulosus short transient receptor potential channel 6 0.0031 0.0032 0.003
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0173 0.0437 0.0751
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0147 0.0363 0.1364
Trichomonas vaginalis Heterochromatin protein, putative 0.0035 0.0045 0.0109
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.1221 0.3414 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2458 0.6927 0.7367
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0046 0.0077 0.0076
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0085 0.0187 0.0186
Onchocerca volvulus 0.0031 0.0033 0.0082
Onchocerca volvulus 0.0639 0.176 0.441
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.001 0.0009
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0031 0.0032 0.003
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0069 0.014 0.0147
Loa Loa (eye worm) TK protein kinase 0.0043 0.0066 0.0124
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0031 0.0032 0.0031
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0037 0.0049 0.0049
Echinococcus multilocularis voltage dependent calcium channel 0.0031 0.0032 0.003
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0023 0.001 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0049 0.0084 0.0145
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0024 0.0012 0.0011
Giardia lamblia NADH oxidase lateral transfer candidate 0.0956 0.2661 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0159 0.0396 0.0394
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0254 0.0666 0.2502
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0254 0.0666 0.2502
Entamoeba histolytica phosphofructokinase, putative 0.0222 0.0575 0.64
Schistosoma mansoni chromobox protein 0.0035 0.0045 0.0044
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0022 0.0006 0.0015
Echinococcus multilocularis g protein coupled receptor 0.0231 0.0601 0.06
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0108 0.0204
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.018 0.0456 0.1337
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0069 0.014 0.0147
Brugia malayi hypothetical protein 0.0101 0.0231 0.0396
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0049 0.0084 0.0211
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0075 0.0157 0.0459
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trichomonas vaginalis apoptosis inducing factor, putative 0.0254 0.0666 0.1666
Schistosoma mansoni hypothetical protein 0.0047 0.0078 0.0078
Mycobacterium ulcerans dehydrogenase 0.0254 0.0666 0.2502
Brugia malayi orphan nuclear receptor NR2E1 0.0023 0.001 0.0018
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0036 0.0046 0.0047
Brugia malayi Dopamine receptor 0.0231 0.0601 0.1032
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.03 0.1127
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0058 0.011 0.0321
Schistosoma mansoni nuclear hormone receptor 0.0023 0.001 0.0009
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0058 0.011 0.0321
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0051 0.009 0.0089
Echinococcus multilocularis potassium voltage gated channel protein 0.0031 0.0032 0.003
Mycobacterium leprae Possible regulatory protein 0.0038 0.0053 0.0165
Toxoplasma gondii NADPH-glutathione reductase 0.0956 0.2661 0.7793
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0036 0.0046 0.0047
Brugia malayi Nuclear hormone receptor E75 0.0023 0.001 0.0018
Brugia malayi Bromodomain containing protein 0.0039 0.0057 0.0098
Schistosoma mansoni neuroligin 3 (S09 family) 0.0058 0.011 0.011
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0031 0.0032 0.003
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.005 0.0049
Brugia malayi hypothetical protein 0.0464 0.1264 0.2171
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0173 0.0437 0.0436
Leishmania major DNA topoisomerase ii 0.0078 0.0167 0.0177
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0231 0.0601 0.0609
Loa Loa (eye worm) hypothetical protein 0.0101 0.0231 0.0435
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0053 0.013
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0024 0.0012 0.0031
Loa Loa (eye worm) intermediate filament protein 0.0106 0.0247 0.0466
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0031 0.0032 0.0054
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0254 0.0666 0.2502
Brugia malayi hypothetical protein 0.0065 0.0129 0.0222
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0038 0.0053 0.0055
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0108 0.0114
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.0006 0.0005
Schistosoma mansoni cellular tumor antigen P53 0.015 0.037 0.0375
Leishmania major hypothetical protein, conserved 0.007 0.0142 0.015
Echinococcus multilocularis thyroid hormone receptor alpha 0.0049 0.0084 0.0083
Brugia malayi Serotonin receptor 0.0231 0.0601 0.1032
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0186 0.0472 0.0501
Trypanosoma cruzi cAMP response protein 1, putative 0.0024 0.0012 0.0011
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0956 0.2661 1
Brugia malayi neuropeptide F receptor 0.0231 0.0601 0.1032
Treponema pallidum catabolite gene activator 0.0024 0.0012 0.0043
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0049 0.0084 0.0084
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0108 0.0253 0.0252
Echinococcus granulosus para nitrobenzyl esterase 0.0058 0.011 0.0108
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0956 0.2661 0.2829
Brugia malayi ABC transporter family protein 0.003 0.003 0.0052
Brugia malayi putative neuropeptide receptor NPR1 0.0231 0.0601 0.1032
Brugia malayi phosphofructokinase 0.0222 0.0575 0.0988
Mycobacterium tuberculosis Possible oxygenase 0.0022 0.0006 0.0017
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.018 0.0456 0.1716
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0035
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0045 0.0044
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0231 0.0601 0.06
Trichomonas vaginalis guanylate cyclase, putative 0.0038 0.0053 0.0131
Echinococcus granulosus survival motor neuron protein 1 0.1195 0.3339 0.3338
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0031 0.0032 0.0031
Echinococcus granulosus single minded 2 0.0123 0.0293 0.0292
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.007 0.007
Loa Loa (eye worm) heterochromatin protein 1 0.0094 0.0212 0.04
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0124 0.0124
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.018 0.0456 0.0455
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0115 0.0285
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0041 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0324 0.081
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0058 0.011 0.0108
Brugia malayi RNA binding protein 0.0062 0.0121 0.0208
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0037 0.0049 0.0121
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0045 0.0044
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0231 0.0601 0.1032
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0025 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Schistosoma mansoni hypothetical protein 0.0101 0.0233 0.0235
Loa Loa (eye worm) steroid hormone receptor 0.0049 0.0084 0.0159
Brugia malayi nuclear hormone receptor 0.0023 0.001 0.0018
Echinococcus granulosus inositol monophosphatase 1 0.0186 0.0472 0.0471
Brugia malayi olfactory channel protein osm-9 0.0031 0.0033 0.0056
Echinococcus multilocularis tyrosine protein kinase Blk 0.0043 0.0066 0.0065
Leishmania major acetoin dehydrogenase e3 component-like protein 0.2458 0.6927 0.7367
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0046 0.0045
Brugia malayi Carboxylesterase family protein 0.0058 0.011 0.0188
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0072 0.007
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0231 0.0601 0.1032
Loa Loa (eye worm) hypothetical protein 0.0057 0.0107 0.0203
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0075 0.0157 0.0589
Schistosoma mansoni histamine h1 receptor 0.0231 0.0601 0.0609
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0054 0.0099 0.0099
Echinococcus multilocularis aryl hydrocarbon receptor 0.0038 0.0053 0.0052
Echinococcus granulosus TRP transient receptor potential channel 0.0031 0.0032 0.003
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.077 0.2131 0.366
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.018 0.0455 0.0482
Loa Loa (eye worm) hypothetical protein 0.006 0.0114 0.0216
Plasmodium falciparum glutathione reductase 0.1221 0.3414 1
Schistosoma mansoni ap endonuclease 0.0058 0.0108 0.0109
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0034 0.0041 0.0071
Entamoeba histolytica hypothetical protein 0.0035 0.0045 0.0496
Echinococcus multilocularis sex peptide receptor 0.0231 0.0601 0.06
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0132 0.0318 0.0317
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0031 0.0032 0.0054
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0004 0.0007
Brugia malayi Immunoglobulin I-set domain containing protein 0.0068 0.0139 0.0239
Toxoplasma gondii phosphofructokinase domain-containing protein 0.006 0.0115 0.0334
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0075 0.0157 0.0589
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0215 0.0554 0.0553
Echinococcus multilocularis neuropeptide Y receptor 0.0231 0.0601 0.06
Trypanosoma brucei ABC transporter, putative 0.0036 0.0046 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0049 0.0084 0.0145
Echinococcus granulosus voltage gated potassium channel 0.0031 0.0032 0.003
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0254 0.0666 0.0664
Echinococcus multilocularis G protein coupled receptor 139 0.0231 0.0601 0.06
Plasmodium vivax thioredoxin reductase, putative 0.1221 0.3414 1
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0036 0.0046 0.0172
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.018 0.0455 0.0461
Loa Loa (eye worm) apoptosis regulator protein 0.0085 0.0187 0.0353
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Schistosoma mansoni jun-related protein 0.0275 0.0724 0.0734
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0254 0.0666 0.0707
Loa Loa (eye worm) melatonin receptor type 1A 0.0231 0.0601 0.1134
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0187 0.0476 0.0474
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0085 0.0187 0.0186
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0037 0.0049 0.0085
Brugia malayi FAT domain containing protein 0.0026 0.0019 0.0033
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0524 0.1312
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0046 0.0113
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0024 0.0012 0.0031
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0038 0.0053 0.0101
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0045 0.0073 0.0072
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0222 0.0575 0.1779
Echinococcus multilocularis neuropeptides capa receptor 0.0231 0.0601 0.06
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0254 0.0666 0.2498
Trypanosoma cruzi NADH dehydrogenase, putative 0.0254 0.0666 0.0707
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0956 0.2661 0.2829
Schistosoma mansoni ap endonuclease 0.0058 0.0108 0.0109
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0046 0.0169
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0075 0.0157 0.0589
Echinococcus granulosus potassium voltage gated channel protein 0.0031 0.0032 0.003
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0031 0.0032 0.0079
Mycobacterium ulcerans hypothetical protein 0.0024 0.0012 0.0044
Brugia malayi Heterochromatin protein 1 0.0094 0.0212 0.0364
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0639 0.176 0.3022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0045 0.0109
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0031 0.0032 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0116 0.0287
Brugia malayi hypothetical protein 0.0223 0.0577 0.099
Brugia malayi Cytochrome P450 family protein 0.0101 0.0232 0.0398
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0024 0.0012 0.0011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0084 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.022 0.0548
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0231 0.0244
Loa Loa (eye worm) cytochrome P450 0.0075 0.0157 0.0295
Echinococcus granulosus neuropeptide Y receptor 0.0231 0.0601 0.06
Schistosoma mansoni adrenodoxin 0.0022 0.0006 0.0005
Brugia malayi Serotonin receptor 0.207 0.5823 1
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Brugia malayi nuclear receptor NHR-67 0.0023 0.001 0.0018
Echinococcus granulosus calcium activated potassium channel 0.0032 0.0037 0.0036
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0078 0.0134
Brugia malayi ecdysone receptor 0.0023 0.001 0.0018
Trypanosoma cruzi NADH dehydrogenase, putative 0.0254 0.0666 0.0707
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0173 0.0437 0.0825
Onchocerca volvulus 0.0231 0.0601 0.1507
Echinococcus multilocularis potassium voltage gated channel protein 0.0031 0.0032 0.003
Onchocerca volvulus 0.0464 0.1264 0.3168
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0045 0.0494
Echinococcus multilocularis FTZ F1 alpha 0.0049 0.0084 0.0083
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0132 0.0318 0.0317
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0075 0.0157 0.0589
Leishmania major trypanothione reductase 0.1221 0.3414 0.363
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0928 0.2581 0.4869
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.018 0.0455 0.0482
Loa Loa (eye worm) voltage-dependent calcium channel 0.0031 0.0032 0.006
Loa Loa (eye worm) hypothetical protein 0.1195 0.3339 0.6299
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0046 0.0077 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0031 0.0032 0.003
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0001 0.0004
Loa Loa (eye worm) phosphatidylinositol 3 0.018 0.0455 0.0858
Onchocerca volvulus 0.0254 0.0666 0.1668
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0084 0.0083
Trichomonas vaginalis glucosylceramidase, putative 0.077 0.2131 0.5341
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0045 0.0073 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0324 0.081
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0031 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Loa Loa (eye worm) hypothetical protein 0.0494 0.1347 0.2541
Echinococcus granulosus hypothetical protein 0.2989 0.8434 0.8433
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0062
Loa Loa (eye worm) G-protein coupled receptor 0.0231 0.0601 0.1134
Brugia malayi CHD4 protein 0.0039 0.0055 0.0094
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0132 0.0318 0.0337
Trichomonas vaginalis chromobox protein, putative 0.0094 0.0212 0.0529
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0075 0.0157 0.0165
Onchocerca volvulus 0.0108 0.0253 0.0634
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0024 0.0012 0.0011
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1471 0.4124 0.7083
Plasmodium vivax ferredoxin, putative 0.0022 0.0006 0.0014
Loa Loa (eye worm) hypothetical protein 0.0042 0.0064 0.0121
Schistosoma mansoni netrin receptor unc5 0.005 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0648 0.1787 0.337
Leishmania major protein kinase A regulatory subunit, putative 0.0024 0.0012 0.0011
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0022 0.0006 0.0022
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1158 0.3233 0.947
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0254 0.0666 0.1666
Brugia malayi hypothetical protein 0.0265 0.0698 0.1199
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0046 0.0079
Trichomonas vaginalis glucosylceramidase, putative 0.0505 0.1379 0.3456
Treponema pallidum fructose-bisphosphate aldolase 0.0301 0.0801 0.3008
Schistosoma mansoni sulfide quinone reductase 0.0254 0.0666 0.0675
Brugia malayi glutathione reductase 0.1221 0.3414 0.5863
Echinococcus granulosus RUN 0.0159 0.0396 0.0394
Trichomonas vaginalis glucosylceramidase, putative 0.0505 0.1379 0.3456
Toxoplasma gondii thioredoxin reductase 0.1221 0.3414 1
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0075 0.0157 0.0459
Trypanosoma brucei Flagellar Member 6 0.0024 0.0012 0.0011
Leishmania major phosphatidylinositol 3-kinase, putative 0.006 0.0116 0.0122
Brugia malayi Protein kinase domain containing protein 0.0044 0.0069 0.0118
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0085
Loa Loa (eye worm) 6-phosphofructokinase 0.0222 0.0575 0.1085
Echinococcus granulosus ryanodine receptor 44f 0.0031 0.0032 0.003
Schistosoma mansoni zinc finger protein 0.0022 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Schistosoma mansoni zinc finger protein 0.0023 0.001 0.0009
Echinococcus granulosus thioredoxin glutathione reductase 0.1221 0.3414 0.3413
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0049 0.0085 0.016
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0108 0.0253 0.0255
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0022 0.0006 0.0017
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0956 0.2661 0.266
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0226 0.0587 0.1008
Onchocerca volvulus Glucosylceramidase homolog 0.0505 0.1379 0.3457
Brugia malayi chromobox protein homolog 3 0.0063 0.0124 0.0213
Echinococcus multilocularis lamin dm0 0.0106 0.0247 0.0246
Echinococcus granulosus nuclear receptor nhr 48 0.0023 0.001 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0072 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0155 0.0451
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0024 0.0012 0.002
Onchocerca volvulus Protein ultraspiracle homolog 0.0049 0.0084 0.0211
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.006 0.0114 0.012
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0254 0.0666 0.1666
Schistosoma mansoni hypothetical protein 0.0042 0.0064 0.0063
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0254 0.0666 0.1947
Loa Loa (eye worm) hypothetical protein 0.0068 0.0138 0.026
Mycobacterium ulcerans hypothetical protein 0.0024 0.0012 0.0044
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0024 0.0012 0.0011
Trypanosoma brucei cAMP binding protein, putative 0.0024 0.0012 0.0011
Leishmania major hypothetical protein, conserved 0.0101 0.0231 0.0244
Brugia malayi Tachykinin-like peptides receptor 99D 0.0231 0.0601 0.1032
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0085
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.018 0.0455 0.0781
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0231 0.0601 0.1032
Trichomonas vaginalis xanthine dehydrogenase, putative 0.067 0.1846 0.4627
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0231 0.0601 0.06
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0737
Mycobacterium ulcerans carboxylesterase, LipT 0.0058 0.011 0.0412
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.03 0.0299
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0186 0.0472 0.1776
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0121 0.0122
Echinococcus multilocularis transient receptor potential cation channel 0.0031 0.0033 0.0031
Loa Loa (eye worm) ABC transporter 0.003 0.003 0.0057
Plasmodium vivax glutathione reductase, putative 0.1221 0.3414 1
Brugia malayi hypothetical protein 0.0494 0.1347 0.2313
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0049 0.0084 0.0159
Onchocerca volvulus 0.0231 0.0601 0.1507
Schistosoma mansoni voltage-dependent calcium channel 0.0031 0.0032 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.0505 0.1379 0.3456
Schistosoma mansoni hypothetical protein 0.0231 0.0601 0.0609
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0019 0.0045
Echinococcus granulosus neuropeptide receptor 0.0231 0.0601 0.06
Echinococcus multilocularis neuroligin 0.0058 0.011 0.0108
Brugia malayi nuclear hormone receptor family member nhr-6 0.0023 0.001 0.0018
Schistosoma mansoni lamin 0.0106 0.0247 0.0249
Entamoeba histolytica DNA topoisomerase II, putative 0.0078 0.0167 0.1857
Schistosoma mansoni cpg binding protein 0.0031 0.0034 0.0033
Schistosoma mansoni neuropeptide receptor 0.0231 0.0601 0.0609
Echinococcus granulosus lamin dm0 0.0106 0.0247 0.0246
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0054 0.0099 0.0186
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0121 0.0122
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.007 0.0142 0.015
Echinococcus granulosus ATP binding cassette sub family G 0.0036 0.0046 0.0044
Echinococcus multilocularis sodium channel protein 0.0241 0.0629 0.0628
Entamoeba histolytica phosphofructokinase, putative 0.0222 0.0575 0.64
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0054 0.0099 0.0098
Loa Loa (eye worm) voltage-gated potassium channel 0.0031 0.0032 0.006
Echinococcus granulosus neuropeptides capa receptor 0.0231 0.0601 0.06
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.03 0.0875
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0024 0.0012 0.0035
Echinococcus granulosus rhodopsin orphan GPCR 0.0231 0.0601 0.06
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0085 0.0187 0.0189
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1158 0.3233 0.947
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0075 0.0157 0.0459
Echinococcus multilocularis Chromo domain 0.0035 0.0045 0.0044
Trichomonas vaginalis Ferredoxin 4 0.0022 0.0006 0.0012
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0186 0.0472 0.0501
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0084 0.0083
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0063 0.0154
Schistosoma mansoni glutamate synthase 0.0254 0.0666 0.0675
Loa Loa (eye worm) hypothetical protein 0.0106 0.0247 0.0466
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0231 0.0244
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0078 0.0167 0.0177
Trichomonas vaginalis glucosylceramidase, putative 0.0532 0.1457 0.3649
Schistosoma mansoni sodium-dependent amino acid transporter 0.0108 0.0253 0.0255
Echinococcus multilocularis fmrfamide receptor 0.0231 0.0601 0.06
Schistosoma mansoni transient receptor potential channel 4 0.0031 0.0032 0.0031
Echinococcus granulosus histone lysine methyltransferase setb 0.0198 0.0506 0.0505
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.018 0.0456 0.0462
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0231 0.0601 0.1134
Echinococcus multilocularis thioredoxin glutathione reductase 0.1221 0.3414 0.3413
Echinococcus multilocularis g-protein coupled receptor 0.0231 0.0601 0.06
Echinococcus granulosus g protein coupled receptor 0.0231 0.0601 0.06
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.077 0.2131 0.4021
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0254 0.0666 0.1947
Loa Loa (eye worm) hypothetical protein 0.0042 0.0065 0.0122
Echinococcus granulosus neuroligin 0.0058 0.011 0.0108
Echinococcus multilocularis transient receptor potential gamma protein 0.0031 0.0032 0.003
Chlamydia trachomatis thioredoxin reductase 0.0254 0.0666 0.2498
Loa Loa (eye worm) hypothetical protein 0.0078 0.0165 0.0312
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0034 0.0041 0.0042
Echinococcus granulosus shaker cognate 0.0031 0.0032 0.003
Echinococcus multilocularis chromobox protein 2 0.0035 0.0045 0.0044
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0108 0.0114
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0024 0.0012 0.0022
Schistosoma mansoni lipoxygenase 0.0698 0.1926 0.1954
Brugia malayi Blistered cuticle protein 3 0.0146 0.036 0.0619
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.03 0.0318
Echinococcus multilocularis hyperpolarization activated cyclic 0.0054 0.0099 0.0098
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0075 0.0157 0.0589
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Schistosoma mansoni biogenic amine (5HT) receptor 0.0595 0.1634 0.1658
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0072 0.007
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0022 0.0006 0.0014
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0058 0.011 0.0272
Schistosoma mansoni transient receptor potential channel 0.0031 0.0032 0.0031
Brugia malayi Cyclic-nucleotide gated cation channel 0.0054 0.0099 0.017
Trypanosoma cruzi cytochrome P450, putative 0.0101 0.0232 0.0245
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0026 0.0018 0.0017
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0231 0.0601 0.06
Echinococcus multilocularis RUN 0.0159 0.0396 0.0394
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.002 0.0001 0.0003
Leishmania major hypothetical protein, unknown function 0.0024 0.0012 0.0011
Loa Loa (eye worm) 6-phosphofructokinase 0.0222 0.0575 0.1085
Brugia malayi Pre-SET motif family protein 0.018 0.0456 0.0783
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0121 0.0122
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0031 0.0032 0.003
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0031 0.0032 0.003
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.006 0.0115 0.0334
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0031 0.0032 0.0054
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0031 0.0032 0.003
Trypanosoma cruzi cytochrome P450, putative 0.0101 0.0232 0.0245
Brugia malayi protein-tyrosine kinase 0.0043 0.0066 0.0113
Echinococcus granulosus BC026374 protein S09 family 0.0058 0.011 0.0108
Brugia malayi Nuclear hormone receptor-like 1 0.0049 0.0084 0.0145
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0035 0.0045 0.0077
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0231 0.0601 0.06
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.006 0.0115 0.0428
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0198 0.0506 0.0512
Echinococcus granulosus cGMP dependent protein kinase 0.0025 0.0017 0.0016
Trypanosoma brucei electron transfer protein, putative 0.0022 0.0006 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.018 0.0455 0.1137
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.0041 0.004
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0037 0.0049 0.0051
Echinococcus multilocularis shaker cognate 0.0031 0.0032 0.003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0063 0.0154
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0024 0.0012 0.004
Onchocerca volvulus Neuropeptide F receptor homolog 0.0231 0.0601 0.1507
Loa Loa (eye worm) hypothetical protein 0.0198 0.0506 0.0954
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0054 0.0099 0.0098
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0254 0.0666 0.2059
Echinococcus multilocularis serotonin receptor 0.06 0.1649 0.1648
Echinococcus multilocularis survival motor neuron protein 1 0.1195 0.3339 0.3338
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0054 0.0099 0.0098
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0187 0.0476 0.0482
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.0366 0.0629
Echinococcus multilocularis nuclear receptor nhr 48 0.0023 0.001 0.0009
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0045 0.0109
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0023 0.001 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0049 0.0085 0.016
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0023 0.001 0.0009
Plasmodium falciparum ferrodoxin reductase-like protein 0.0254 0.0666 0.1947
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143 0.035 0.0876
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0198 0.0506 0.0505
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0068 0.0139 0.0263
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0324 0.081
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0035 0.0045 0.0044
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0108 0.0253 0.0252
Mycobacterium ulcerans hypothetical protein 0.0024 0.0012 0.0044
Brugia malayi Protein cec-1. 0.0035 0.0045 0.0077
Plasmodium falciparum LCCL domain-containing protein 0.0159 0.0396 0.1155
Plasmodium vivax hypothetical protein, conserved 0.0108 0.0253 0.0737
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0075 0.0157 0.0589
Echinococcus granulosus geminin 0.0855 0.2373 0.2373
Onchocerca volvulus 0.0159 0.0396 0.0991
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0077 0.0076
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Loa Loa (eye worm) voltage-gated calcium channel 0.0031 0.0032 0.006
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.007 0.0142 0.015
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Brugia malayi ion channel NompC 0.0031 0.0032 0.0054
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0046 0.0045
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0046 0.0077 0.0076
Schistosoma mansoni steroid hormone receptor ad4bp 0.0049 0.0084 0.0084
Echinococcus granulosus neuropeptide s receptor 0.1158 0.3234 0.3233
Echinococcus granulosus transient receptor potential cation channel 0.0031 0.0033 0.0031
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0108 0.0268
Loa Loa (eye worm) hypothetical protein 0.0101 0.0233 0.0439
Onchocerca volvulus 0.0231 0.0601 0.1507
Loa Loa (eye worm) acetylcholinesterase 1 0.0344 0.0921 0.1738
Loa Loa (eye worm) hypothetical protein 0.0058 0.0111 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Trypanosoma cruzi cAMP binding protein, putative 0.0024 0.0012 0.0011
Echinococcus multilocularis neuropeptide s receptor 0.1158 0.3234 0.3233
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2458 0.6927 0.7367
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0198 0.0506 0.0512
Loa Loa (eye worm) thioredoxin reductase 0.1221 0.3414 0.644
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0231 0.0601 0.06
Leishmania major hypothetical protein, conserved 0.0254 0.0666 0.0707
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0077 0.0076
Echinococcus granulosus bloom syndrome protein 0.0021 0.0004 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0324 0.081
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.03 0.0303
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0956 0.2661 0.2829
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0254 0.0666 0.1947
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0031 0.0032 0.0054
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0049 0.0084 0.0083
Toxoplasma gondii cytochrome p450 superfamily protein 0.0075 0.0157 0.0455
Loa Loa (eye worm) CHromoDomain protein family member 0.0039 0.0055 0.0104
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0038 0.0053 0.0131
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Schistosoma mansoni cpg binding protein 0.0028 0.0023 0.0023
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0024 0.0012 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0049 0.0084 0.0159
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0034 0.0041 0.0042
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0049 0.0084 0.0083
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0024 0.0012 0.0011
Schistosoma mansoni hypothetical protein 0.0159 0.0396 0.04
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0004 0.0003
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0226 0.0587 0.1719
Echinococcus multilocularis g protein coupled receptor 0.0231 0.0601 0.06
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0231 0.0601 0.1134
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0045 0.0109
Brugia malayi hypoxia-induced factor 1 0.0456 0.1238 0.2127
Loa Loa (eye worm) hypothetical protein 0.0206 0.0529 0.0998
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0045 0.0128
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0254 0.0666 0.0664
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0204 0.0524 0.0556
Plasmodium falciparum DNA topoisomerase 2 0.0078 0.0167 0.0486
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0084 0.0145
Echinococcus granulosus potassium voltage gated channel protein 0.0031 0.0032 0.003
Schistosoma mansoni polycystin 1-related 0.0159 0.0396 0.04
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0956 0.2661 1
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0031 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0098
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0039 0.0055 0.0055
Toxoplasma gondii FATC domain-containing protein 0.0034 0.0041 0.0117
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0024 0.0012 0.0011
Schistosoma mansoni hypothetical protein 0.0021 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0207
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0075 0.0157 0.0589
Brugia malayi Carboxylesterase family protein 0.0344 0.0921 0.1582
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0045 0.0128
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.018 0.0455 0.5059
Loa Loa (eye worm) hypothetical protein 0.0254 0.0666 0.1256
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0023 0.001 0.0009
Loa Loa (eye worm) inositol-1 0.0186 0.0472 0.0891
Giardia lamblia Thioredoxin reductase 0.0254 0.0666 0.2498
Onchocerca volvulus 0.0231 0.0601 0.1507
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0049 0.0084 0.0159
Echinococcus multilocularis voltage gated potassium channel 0.0068 0.0138 0.0136
Schistosoma mansoni alpha-1 adrenergic receptor 0.0231 0.0601 0.0609
Loa Loa (eye worm) hypothetical protein 0.0108 0.0253 0.0477
Echinococcus granulosus serotonin receptor 0.0231 0.0601 0.06
Brugia malayi cytoplasmic intermediate filament protein 0.0057 0.0107 0.0183
Echinococcus multilocularis ecdysone induced protein 78C 0.0049 0.0084 0.0083
Entamoeba histolytica hypothetical protein 0.0035 0.0045 0.0494
Echinococcus multilocularis acetylcholinesterase 0.0344 0.0921 0.092
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0115 0.0285
Echinococcus granulosus Immunoglobulin 0.0051 0.0091 0.009
Schistosoma mansoni hypothetical protein 0.0231 0.0601 0.0609
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0116 0.0287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.022 0.0549
Schistosoma mansoni hypothetical protein 0.0254 0.0666 0.0675
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0058 0.011 0.0108
Trypanosoma brucei cytochrome P450, putative 0.0101 0.0232 0.0245
Echinococcus multilocularis potassium voltage gated channel protein 0.0031 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0022 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0222 0.0576 0.1086
Echinococcus granulosus transcription factor Dp 1 0.0076 0.0161 0.016
Mycobacterium ulcerans electron transfer protein 0.0022 0.0006 0.0022
Echinococcus multilocularis voltage dependent calcium channel 0.0031 0.0032 0.003
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0031 0.0032 0.003
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0114 0.0112
Schistosoma mansoni lamin 0.0106 0.0247 0.0249
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.333 0.9402 1
Brugia malayi 6-phosphofructokinase 0.0222 0.0576 0.099
Trichomonas vaginalis Ferredoxin 2 0.0022 0.0006 0.0012
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0108 0.0114
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0956 0.2661 0.7793
Mycobacterium ulcerans glutaminase 0.0267 0.0704 0.2645
Schistosoma mansoni opsin-like receptor 0.0231 0.0601 0.0609
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0254 0.0666 0.195
Brugia malayi cytochrome P450 0.0075 0.0157 0.0269
Echinococcus multilocularis jun protein 0.0338 0.0904 0.0903
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0121 0.0208
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.001 0.0009
Echinococcus multilocularis mitogen activated protein kinase 0.0204 0.0524 0.0523
Schistosoma mansoni voltage-gated potassium channel 0.0068 0.0138 0.0138
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0231 0.0601 0.1507
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0254 0.0666 0.1947
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0254 0.0666 0.1947
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0132 0.0318 0.0337
Echinococcus multilocularis Polycystic kidney disease protein 0.0159 0.0396 0.0394
Entamoeba histolytica hypothetical protein 0.0035 0.0045 0.0496
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.018 0.0455 0.5059
Schistosoma mansoni loxhd1 0.0159 0.0396 0.04
Trichomonas vaginalis chromobox protein, putative 0.0094 0.0212 0.0529
Echinococcus multilocularis zinc finger protein 0.0022 0.0007 0.0005
Echinococcus granulosus Adrenodoxin mitochondrial 0.0022 0.0006 0.0005
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Leishmania major protein kinase, putative 0.0025 0.0017 0.0017
Loa Loa (eye worm) carboxylesterase 0.0344 0.0921 0.1738
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0038 0.0053 0.0052
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0075 0.0157 0.0589
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0045 0.0044
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0215 0.0556 0.0563
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0045 0.0044
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0037 0.0049 0.0141
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0231 0.0601 0.06
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0052 0.0128
Schistosoma mansoni intermediate filament proteins 0.0106 0.0247 0.0249
Echinococcus granulosus voltage gated potassium channel 0.0068 0.0138 0.0136
Echinococcus granulosus neuropeptide Y receptor 0.0231 0.0601 0.06
Brugia malayi Dopamine receptor protein 1 0.0231 0.0601 0.1032
Schistosoma mansoni biogenic amine receptor 0.0231 0.0601 0.0609
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0077 0.0076
Loa Loa (eye worm) hypothetical protein 0.0058 0.0111 0.0209
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.006 0.0115 0.0431
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0022 0.0006 0.0011
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0166 0.0417 0.129
Trichomonas vaginalis glucosylceramidase, putative 0.077 0.2131 0.5341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0041 0.01
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0062
Echinococcus multilocularis fmrfamide receptor 0.0231 0.0601 0.06
Loa Loa (eye worm) hypothetical protein 0.0057 0.0107 0.0203
Echinococcus granulosus Chromobox protein 3 0.0035 0.0045 0.0044
Leishmania major cyclic nucleotide-binding protein-like protein 0.0024 0.0012 0.0011
Echinococcus multilocularis transfer RNA-Lys 0.0109 0.0254 0.0253
Brugia malayi hypothetical protein 0.0057 0.0107 0.0184
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.0041 0.004
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0049 0.0084 0.0083
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0026 0.0019 0.0018
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0075 0.0157 0.0459
Mycobacterium ulcerans electron transfer protein FdxB 0.0022 0.0006 0.0022
Echinococcus granulosus voltage dependent calcium channel 0.0031 0.0032 0.003
Trypanosoma brucei DNA topoisomerase ii 0.006 0.0114 0.012
Echinococcus granulosus g protein coupled receptor 0.0231 0.0601 0.06
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0108 0.0107
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0254 0.0666 0.1666
Echinococcus multilocularis transient receptor potential cation channel 0.0031 0.0032 0.003
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0046 0.0048
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0241 0.0629 0.0668
Trypanosoma brucei protein kinase A regulatory subunit 0.0024 0.0012 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0049 0.0084 0.0145
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trichomonas vaginalis glucosylceramidase, putative 0.077 0.2131 0.5341
Schistosoma mansoni glutamate synthase 0.0254 0.0666 0.0675
Schistosoma mansoni BC026374 protein (S09 family) 0.0058 0.011 0.011
Toxoplasma gondii ferredoxin, putative 0.0022 0.0006 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2808 0.7919 0.8422
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0075 0.0157 0.0589
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.022 0.0548
Schistosoma mansoni ryanodine receptor related 0.0031 0.0032 0.0031
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0024 0.0012 0.0011
Echinococcus multilocularis conserved hypothetical protein 0.2758 0.7777 0.7777
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0001 0.0002
Treponema pallidum catabolite gene activator (Crp) 0.0024 0.0012 0.0043
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0031 0.0032 0.003
Brugia malayi Transient-receptor-potential like protein 0.0031 0.0032 0.0054
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus granulosus transient receptor potential cation channel 0.0031 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0464 0.1264 0.2385
Echinococcus multilocularis chromobox protein 1 0.0094 0.0212 0.0211
Onchocerca volvulus 0.0222 0.0576 0.1443
Plasmodium falciparum thioredoxin reductase 0.1221 0.3414 1
Loa Loa (eye worm) TK protein kinase 0.0039 0.0055 0.0104
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0254 0.0666 0.1256
Brugia malayi jmjC domain containing protein 0.0063 0.0124 0.0212
Trichomonas vaginalis guanylate cyclase, putative 0.0038 0.0053 0.0131
Entamoeba histolytica hypothetical protein 0.0035 0.0045 0.0496
Echinococcus granulosus transient receptor potential cation channel 0.0031 0.0032 0.003
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0001 0.0005
Loa Loa (eye worm) CYP4Cod1 0.0101 0.0232 0.0438
Schistosoma mansoni voltage-gated potassium channel 0.0054 0.0099 0.0099
Onchocerca volvulus 0.0058 0.011 0.0275
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0022 0.0006 0.0022
Brugia malayi photoreceptor-specific nuclear receptor 0.0049 0.0084 0.0145
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0155 0.0451
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0477
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0121 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0046 0.0113
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.333 0.9402 1
Schistosoma mansoni hypothetical protein 0.0275 0.0724 0.0734
Leishmania major hypothetical protein, conserved 0.0024 0.0012 0.0011
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0038 0.0053 0.0055
Leishmania major ATP-dependent phosphofructokinase 0.0222 0.0575 0.0611
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0115 0.0285
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Trypanosoma cruzi DNA topoisomerase II, putative 0.0078 0.0167 0.0177
Echinococcus granulosus dro:myosuppressin receptor 0.0231 0.0601 0.06
Loa Loa (eye worm) hypothetical protein 0.0536 0.1467 0.2768
Onchocerca volvulus 0.0215 0.0556 0.1393
Echinococcus granulosus ATP binding cassette sub family G 0.0036 0.0046 0.0044
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0108 0.0253 0.0255
Schistosoma mansoni sulfide quinone reductase 0.0254 0.0666 0.0675
Loa Loa (eye worm) hypothetical protein 0.0108 0.0253 0.0477
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0254 0.0666 0.2498
Trypanosoma brucei hypothetical protein, conserved 0.0254 0.0666 0.0707
Leishmania major mitochondrial DNA topoisomerase II 0.006 0.0114 0.012
Echinococcus granulosus rhodopsin orphan GPCR 0.0231 0.0601 0.06
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Loa Loa (eye worm) hypothetical protein 0.004 0.0057 0.0108
Brugia malayi Nuclear hormone receptor E75 0.0023 0.001 0.0018
Plasmodium vivax heterochromatin protein 1, putative 0.0035 0.0045 0.0128
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trypanosoma brucei protein kinase, putative 0.0204 0.0524 0.0556
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Schistosoma mansoni myosin xvIII 0.0231 0.0601 0.0609
Mycobacterium leprae putative cytochrome p450 0.0075 0.0157 0.0484
Echinococcus granulosus hyperpolarization activated cyclic 0.0054 0.0099 0.0098
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0231 0.0601 0.1032
Schistosoma mansoni vesicular amine transporter 0.0082 0.0178 0.0179
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0031 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0022
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0128 0.0308 0.0902
Mycobacterium ulcerans putative regulatory protein 0.0109 0.0254 0.0955
Giardia lamblia ABC transporter 0.0035 0.0044 0.0163
Plasmodium vivax multidomain scavenger receptor, putative 0.0159 0.0396 0.1155
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0108 0.0314
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0049 0.0084 0.0083
Brugia malayi Carboxylesterase family protein 0.0344 0.0921 0.1582
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0254 0.0666 0.7406
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0249 0.0623
Leishmania major dihydrolipoamide dehydrogenase, putative 0.333 0.9402 1
Leishmania major protein kinase, putative 0.004 0.0059 0.0061
Loa Loa (eye worm) hypothetical protein 0.0038 0.0053 0.0101
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0051 0.009 0.0089
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0231 0.0601 0.0609
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0068 0.0138 0.0136
Trichomonas vaginalis glucosylceramidase, putative 0.0505 0.1379 0.3456
Schistosoma mansoni gliotactin 0.0058 0.011 0.011
Echinococcus granulosus potassium voltage gated channel protein 0.0031 0.0032 0.003
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0114 0.0114
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0046 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.022 0.0549
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0022 0.0006 0.0017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0063 0.0154
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0024 0.0012 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0082 0.0201
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.018 0.0456 0.0784
Loa Loa (eye worm) hypothetical protein 0.0046 0.0074 0.014
Loa Loa (eye worm) hypothetical protein 0.0047 0.0078 0.0147
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0186 0.0472 0.0501
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0316 0.0841 0.2464
Echinococcus multilocularis ferredoxin adrenodoxin 0.0022 0.0006 0.0005
Loa Loa (eye worm) serotonin transporter b 0.0639 0.176 0.332
Brugia malayi Uncoordinated protein 44 0.0042 0.0064 0.0109
Trypanosoma brucei C-8 sterol isomerase, putative 0.1471 0.4124 0.4386
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0173 0.0437 0.0436
Echinococcus granulosus g-protein coupled receptor 0.0231 0.0601 0.06
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0132 0.0318 0.3539
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0114 0.0112
Toxoplasma gondii transporter, cation channel family protein 0.0031 0.0032 0.0089
Trichomonas vaginalis Ferredoxin 1 0.0022 0.0006 0.0012
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0226 0.0587 0.2205
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0254 0.0666 0.1666
Echinococcus multilocularis potassium voltage gated channel protein 0.0031 0.0032 0.003
Schistosoma mansoni rab6-interacting 0.0159 0.0396 0.04
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.006 0.0115 0.0428
Trypanosoma brucei PAB1-binding protein , putative 0.0101 0.0231 0.0244
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Echinococcus granulosus transient receptor potential cation channel 0.0031 0.0032 0.003
Onchocerca volvulus 0.0106 0.0247 0.0619
Loa Loa (eye worm) hypothetical protein 0.0148 0.0366 0.0691
Brugia malayi Death domain containing protein 0.0042 0.0064 0.0109
Onchocerca volvulus 0.0231 0.0601 0.1507
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0035 0.0045 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0075 0.0157 0.0459
Leishmania major regulatory subunit of protein kinase a-like protein 0.0024 0.0012 0.0011
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0249 0.0623
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0132 0.0318 0.06
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0254 0.0666 0.2502
Mycobacterium tuberculosis Conserved protein 0.0024 0.0012 0.0035
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.0366 0.0691
Brugia malayi nuclear hormone receptor 0.0049 0.0084 0.0145
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Schistosoma mansoni neuropeptide receptor 0.0231 0.0601 0.0609
Brugia malayi Cytochrome P450 family protein 0.017 0.0428 0.0736
Toxoplasma gondii transporter, cation channel family protein 0.0031 0.0032 0.0089
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0084 0.0145
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0018 0.0032
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0108 0.0268
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0455 0.1238 0.3627
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0222 0.0575 0.0611
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.004 0.0059 0.0061
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.003 0.0029 0.0085
Schistosoma mansoni hypothetical protein 0.0085 0.0187 0.0189
Onchocerca volvulus 0.0231 0.0601 0.1507
Schistosoma mansoni neuropeptide receptor 0.0231 0.0601 0.0609
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0084 0.0083
Echinococcus granulosus cGMP dependent protein kinase 1 0.0025 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.06 0.1649 0.3111
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0476 0.0482
Echinococcus granulosus lipoxygenase domain containing protein 0.0159 0.0396 0.0394
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0024 0.0012 0.0035
Onchocerca volvulus 0.0028 0.0023 0.0059
Brugia malayi Associated with TFs and helicases family protein 0.0035 0.0045 0.0077
Schistosoma mansoni 6-phosphofructokinase 0.0222 0.0575 0.0583
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0254 0.0666 0.2498
Trichomonas vaginalis phosphofructokinase, putative 0.0222 0.0575 0.144
Echinococcus granulosus hyperpolarization activated cyclic 0.0054 0.0099 0.0098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0072 0.0072
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0004 0.0007
Mycobacterium ulcerans monoxygenase 0.0254 0.0666 0.2502
Onchocerca volvulus Dual oxidase homolog 0.0146 0.036 0.0903
Trypanosoma brucei cAMP response protein 1, putative 0.0024 0.0012 0.0011
Onchocerca volvulus 0.0231 0.0601 0.1507
Loa Loa (eye worm) hypothetical protein 0.0108 0.0253 0.0477
Echinococcus multilocularis neuropeptide receptor 0.0231 0.0601 0.06
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0074 0.0155 0.0479
Schistosoma mansoni RAR-like nuclear receptor 0.0049 0.0084 0.0084
Echinococcus granulosus mitogen activated protein kinase 3 0.0204 0.0524 0.0523
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0049 0.0084 0.0084
Schistosoma mansoni hypothetical protein 0.0085 0.0187 0.0189
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.018 0.0455 0.0454
Loa Loa (eye worm) runx1 0.0058 0.011 0.0208
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0022 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0039 0.0054 0.0102
Trypanosoma brucei NADH dehydrogenase 0.0254 0.0666 0.0707
Toxoplasma gondii DNA topoisomerase 2, putative 0.0078 0.0167 0.0486
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0024 0.0012 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0115 0.0285
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0078 0.0167 0.0166
Loa Loa (eye worm) hypothetical protein 0.0051 0.009 0.0171
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0075 0.0157 0.0589
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0254 0.0666 0.2059
Brugia malayi Bromodomain containing protein 0.0079 0.0169 0.029
Echinococcus granulosus tm gpcr rhodopsin 0.0231 0.0601 0.06
Echinococcus multilocularis transient receptor potential cation channel 0.0031 0.0032 0.003
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0031 0.0032 0.003
Brugia malayi hypothetical protein 0.0159 0.0396 0.0679
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0046 0.0048
Toxoplasma gondii selenide, water dikinase 0.0254 0.0666 0.1947
Loa Loa (eye worm) hypothetical protein 0.0039 0.0054 0.0102
Brugia malayi G-protein coupled receptor 0.0231 0.0601 0.1032
Echinococcus multilocularis BC026374 protein (S09 family) 0.0058 0.011 0.0108
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0639 0.176 0.1785
Brugia malayi ORL1-like opioid receptor 0.0231 0.0601 0.1032
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0132 0.0318 0.0547
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0022 0.0006 0.001
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.2458 0.6927 0.7367
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0078 0.0147
Echinococcus granulosus potassium large conductance calcium activated 0.0031 0.0032 0.003
Schistosoma mansoni ABC transporter 0.003 0.003 0.003
Leishmania major ferric reductase, putative 0.0069 0.014 0.0147
Brugia malayi nuclear receptor NHR-88 0.0049 0.0084 0.0145
Echinococcus granulosus tyrosine kinase 0.0043 0.0066 0.0065
Trichomonas vaginalis phosphofructokinase, putative 0.0222 0.0575 0.144
Plasmodium falciparum amino acid transporter, putative 0.0108 0.0253 0.0737
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0063 0.0154
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus multilocularis lamin 0.0106 0.0247 0.0246
Onchocerca volvulus 0.0024 0.0012 0.003
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0075 0.0157 0.0589
Echinococcus multilocularis serine protein kinase ATM 0.0034 0.0041 0.004
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0051 0.0091 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0324 0.081
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0005 0.001
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.001 0.0026
Echinococcus multilocularis chromobox protein 1 0.0094 0.0212 0.0211
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0037 0.0049 0.0051
Echinococcus granulosus transient receptor potential cation channel 0.0031 0.0032 0.003
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0254 0.0666 0.0664
Schistosoma mansoni glutamate synthase 0.0254 0.0666 0.0675
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0023 0.001 0.0009
Loa Loa (eye worm) cytochrome P450 family protein 0.017 0.0428 0.0808
Brugia malayi PHD-finger family protein 0.0027 0.0022 0.0038
Onchocerca volvulus 0.0049 0.0084 0.0211
Echinococcus multilocularis glutamate synthase 0.0254 0.0666 0.0664
Loa Loa (eye worm) hypothetical protein 0.0108 0.0253 0.0477
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0455 0.1238 0.3627
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0254 0.0666 0.0664
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0231 0.0601 0.06
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143 0.035 0.0876
Echinococcus multilocularis Chromobox protein 3 0.0035 0.0045 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0053 0.0131
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.006 0.0114 0.0113
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0075 0.0157 0.0589
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.354 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0072 0.0072
Echinococcus multilocularis ATP binding cassette sub family G 0.0036 0.0046 0.0044
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0108 0.0253 0.0255
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0702 0.194 0.3331
Echinococcus granulosus thyroid hormone receptor alpha 0.0023 0.001 0.0009
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0254 0.0666 0.1666
Echinococcus multilocularis mitogen activated protein kinase 3 0.0204 0.0524 0.0523
Echinococcus multilocularis somatostatin receptor 0.0231 0.0601 0.06
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0034 0.0041 0.0041
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.006 0.0116 0.0115
Mycobacterium ulcerans endonuclease IV 0.0074 0.0155 0.0583
Loa Loa (eye worm) hypothetical protein 0.0073 0.0152 0.0286
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0108 0.0402
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0207
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0031 0.0032 0.0032
Brugia malayi hypothetical protein 0.0026 0.0018 0.0032
Echinococcus granulosus Polycystic kidney disease protein 0.0159 0.0396 0.0394
Entamoeba histolytica hypothetical protein 0.0096 0.0216 0.2401
Echinococcus granulosus 6 phosphofructokinase 0.0222 0.0575 0.0574
Onchocerca volvulus 0.0058 0.011 0.0275
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0031 0.0032 0.0032
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.018 0.0455 0.0482
Echinococcus granulosus tyrosine protein kinase Blk 0.0043 0.0066 0.0065
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0024 0.0012 0.0011
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0001 0.0002
Schistosoma mansoni biogenic amine (5HT) receptor 0.06 0.1649 0.1673
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Echinococcus multilocularis tyrosine protein kinase Srms 0.0043 0.0066 0.0065
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0254 0.0666 0.1947
Schistosoma mansoni nuclear receptor nhr-48 0.0023 0.001 0.0009
Echinococcus multilocularis serotonin receptor 0.06 0.1649 0.1648
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0042 0.0064 0.0062
Loa Loa (eye worm) ryanodine receptor 0.0031 0.0032 0.006
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0046 0.0077 0.0076
Echinococcus multilocularis musashi 0.0106 0.0247 0.0246
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0024 0.0012 0.004
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0054 0.0099 0.0098
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0032 0.0089
Mycobacterium tuberculosis Conserved hypothetical protein 0.0024 0.0012 0.0035
Loa Loa (eye worm) solute carrier family 6 member 4 0.0639 0.176 0.332
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0036 0.0046 0.0045
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0074 0.0155 0.0266
Echinococcus granulosus transient receptor potential gamma protein 0.0031 0.0032 0.003
Mycobacterium tuberculosis Carboxylesterase LipT 0.0058 0.011 0.0321
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0075 0.0157 0.0459
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0115 0.0285
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0049 0.0084 0.0083
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0024 0.0012 0.0031
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0737
Treponema pallidum cyclic nucleotide binding protein 0.0024 0.0012 0.0043
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0001 0.0004
Schistosoma mansoni cpg binding protein 0.0031 0.0034 0.0033
Loa Loa (eye worm) G-protein coupled receptor 0.0231 0.0601 0.1134
Loa Loa (eye worm) TYRA-2 protein 0.0231 0.0601 0.1134
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Brugia malayi RE15519p 0.0231 0.0601 0.1032
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0024 0.0013 0.0038
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0049 0.0084 0.0083
Echinococcus multilocularis neuroglian 0.0051 0.0091 0.009
Schistosoma mansoni growth hormone secretagogue receptor 0.0231 0.0601 0.0609
Echinococcus granulosus lysine specific demethylase 5A 0.0063 0.0124 0.0123
Echinococcus multilocularis neuropeptides capa receptor 0.0231 0.0601 0.06
Mycobacterium ulcerans regulatory protein 0.0024 0.0012 0.0044
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0254 0.0666 0.0707
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0057 0.0107 0.0201
Echinococcus granulosus peptide allatostatin:somatostatin 0.0231 0.0601 0.06
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0038 0.0053 0.0131
Echinococcus multilocularis 6 phosphofructokinase 0.0222 0.0575 0.0574
Schistosoma mansoni amine GPCR 0.0231 0.0601 0.0609
Schistosoma mansoni hypothetical protein 0.0047 0.0078 0.0078
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0031 0.0032 0.003
Echinococcus multilocularis lipoxygenase domain containing protein 0.0159 0.0396 0.0394
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0092
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0024 0.0012 0.0011
Mycobacterium ulcerans hypothetical protein 0.0024 0.0012 0.0044
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0015 0.0014
Toxoplasma gondii transporter, cation channel family protein 0.0031 0.0032 0.0089
Toxoplasma gondii hypothetical protein 0.0031 0.0032 0.0089
Echinococcus granulosus ferredoxin 0.0022 0.0006 0.0005
Echinococcus multilocularis GPCR, family 2 0.0047 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Leishmania major cytochrome p450-like protein 0.0075 0.0157 0.0165
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0254 0.0666 0.0664
Toxoplasma gondii hypothetical protein 0.0031 0.0032 0.0089
Echinococcus multilocularis expressed conserved protein 0.0025 0.0017 0.0016
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0024 0.0012 0.0027
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0434
Brugia malayi glutamate synthase 0.0254 0.0666 0.1143
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0046 0.0077 0.0076
Echinococcus granulosus Ankyrin 0.0042 0.0065 0.0063
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0075 0.0157 0.0589
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0017 0.0016
Plasmodium falciparum transporter, putative 0.0108 0.0253 0.0737
Echinococcus granulosus g protein coupled receptor 0.0231 0.0601 0.06
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0049 0.0084 0.0145
Brugia malayi conserved hypotetical protein 0.0023 0.001 0.0018
Echinococcus multilocularis 0.0075 0.0157 0.0155
Echinococcus granulosus acetylcholinesterase 0.0344 0.0921 0.092
Mycobacterium ulcerans transcriptional regulatory protein 0.0024 0.0012 0.0044
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0254 0.0666 0.0664
Echinococcus multilocularis short transient receptor potential channel 6 0.0031 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus granulosus microtubule associated protein 2 0.3487 0.985 0.985
Echinococcus multilocularis dnaJ subfamily B 0.0395 0.1067 0.1066
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0124 0.0308
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0024 0.0012 0.0027
Loa Loa (eye worm) nuclear hormone receptor 0.0023 0.001 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.077 0.2131 0.5341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143 0.035 0.0876
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0049 0.0084 0.0084
Mycobacterium leprae Conserved hypothetical protein 0.0024 0.0012 0.0037
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0254 0.0666 0.2059
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0039 0.0055 0.0054
Schistosoma mansoni amine GPCR 0.0231 0.0601 0.0609
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0049 0.0084 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0249 0.0623
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0036 0.0046 0.0172
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0053 0.0131
Echinococcus granulosus tyrosine protein kinase HCK 0.0039 0.0055 0.0054
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0022 0.0006 0.0005
Treponema pallidum oxidoreductase 0.0254 0.0666 0.25
Trichomonas vaginalis spcc417.12 protein, putative 0.0058 0.011 0.0272
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Leishmania major hypothetical protein, conserved 0.0254 0.0666 0.0707
Loa Loa (eye worm) neuropeptide F receptor 0.0231 0.0601 0.1134
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0045 0.0044
Brugia malayi Pre-SET motif family protein 0.1251 0.3498 0.6008
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0075 0.0157 0.0459
Echinococcus granulosus two pore calcium channel protein 2 0.0031 0.0032 0.003
Brugia malayi glutaminase DH11.1 0.0267 0.0704 0.1209
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.0524 0.0531
Mycobacterium ulcerans transmembrane transport protein 0.0024 0.0012 0.0044
Schistosoma mansoni sodium/chloride dependent transporter 0.0639 0.176 0.1785
Plasmodium vivax DNA topoisomerase II, putative 0.0078 0.0167 0.0486
Loa Loa (eye worm) norepinephrine transporter 0.0639 0.176 0.332
Toxoplasma gondii endonuclease IV APN 0.0074 0.0155 0.0451
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0254 0.0666 0.1143
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0455 0.1238 0.3829
Onchocerca volvulus 0.0023 0.001 0.0026
Brugia malayi 6-phosphofructokinase 0.0222 0.0575 0.0988
Schistosoma mansoni nuclear hormone receptor 0.0023 0.001 0.0009
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0101 0.0232 0.0872
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0078 0.0167 0.0177
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0524 0.1312
Trypanosoma brucei trypanothione reductase 0.1221 0.3414 0.363
Echinococcus granulosus acetylcholinesterase 0.0344 0.0921 0.092
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0108 0.0114
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0956 0.2661 0.7793
Trypanosoma cruzi Flagellar Member 6 0.0024 0.0012 0.0011
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0108 0.0407
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0042 0.0064 0.0237
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0045 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Mycobacterium tuberculosis Probable reductase 0.0455 0.1238 0.3627
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0031 0.0032 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143 0.035 0.0876
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0116 0.0287
Schistosoma mansoni biogenic amine receptor 0.0231 0.0601 0.0609
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0037 0.0049 0.0085
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0075 0.0157 0.0459
Schistosoma mansoni disulfide oxidoreductase 0.0254 0.0666 0.0675
Echinococcus multilocularis transfer RNA-Gly 0.0031 0.0032 0.003
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0198 0.0508 0.1911
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0024 0.0012 0.0011
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0037 0.0049 0.0545
Toxoplasma gondii Erv1 / Alr family protein 0.007 0.0142 0.0414
Brugia malayi Immunoglobulin I-set domain containing protein 0.005 0.0087 0.015
Mycobacterium tuberculosis Probable oxidoreductase 0.1158 0.3233 0.947
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0037 0.0049 0.0121
Brugia malayi hypothetical protein 0.1195 0.3339 0.5734
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0444 0.1204 0.4527
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0316 0.0841 0.3162
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0031 0.0032 0.0032
Plasmodium vivax ferrodoxin reductase, putative 0.0254 0.0666 0.1947
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0108 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0254 0.0666 0.2498
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0045 0.0044
Schistosoma mansoni fkbp-rapamycin associated protein 0.0034 0.0041 0.0041
Schistosoma mansoni nuclear receptor 0.0023 0.001 0.0009
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0037 0.0049 0.0141
Echinococcus multilocularis sodium leak channel non selective protein 0.0031 0.0032 0.003
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0037 0.0049 0.0051
Trichomonas vaginalis glucosylceramidase, putative 0.077 0.2131 0.5341
Loa Loa (eye worm) neuropeptide F receptor 0.0231 0.0601 0.1134
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0956 0.2661 0.7793
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0698 0.1926 0.1925
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0046 0.0048
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0078 0.0167 0.0287
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.018 0.0456 0.0484
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0254 0.0666 0.195
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0004 0.0007
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0046 0.0046
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.006 0.0116 0.0199
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0069 0.014 0.0147
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0956 0.2661 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0159 0.0396 0.0394
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.001 0.0009
Leishmania major hypothetical protein, conserved 0.0024 0.0012 0.0011
Schistosoma mansoni nephrin 0.0057 0.0107 0.0108
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0108 0.0253 0.0255
Echinococcus multilocularis short transient receptor potential channel 6 0.0031 0.0033 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0116 0.0287
Trichomonas vaginalis aldehyde oxidase, putative 0.067 0.1846 0.4627
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0043 0.0066 0.0065
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0131 0.0131
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0231 0.0673
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0226 0.0587 0.1107
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0078 0.0077
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0084 0.0145
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0108 0.0253 0.0434
Trypanosoma cruzi ABC transporter, putative 0.0036 0.0046 0.0047
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0046 0.0509
Entamoeba histolytica hypothetical protein 0.0035 0.0045 0.0496
Mycobacterium ulcerans oxidoreductase 0.0022 0.0006 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.012 0.0287 0.0716
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Toxoplasma gondii ferodoxin FD 0.0022 0.0006 0.0014
Echinococcus granulosus FTZ F1 alpha 0.0049 0.0084 0.0083
Onchocerca volvulus Netrin receptor homolog 0.0052 0.0094 0.0235
Loa Loa (eye worm) hypoxia-induced factor 1 0.0456 0.1238 0.2336
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Schistosoma mansoni voltage-gated potassium channel 0.0068 0.0138 0.0138
Toxoplasma gondii hypothetical protein 0.0108 0.0253 0.0737
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0186 0.0472 0.5255
Echinococcus granulosus nuclear factor of activated T cells 5 0.0215 0.0554 0.0553
Echinococcus multilocularis ATP binding cassette sub family G 0.0036 0.0046 0.0044
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.012 0.0347
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0254 0.0666 0.1143
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0254 0.0666 0.195
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0046 0.0045
Echinococcus multilocularis calcium activated potassium channel 0.0032 0.0037 0.0036
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0254 0.0666 0.0664
Loa Loa (eye worm) doublecortin family protein 0.0159 0.0396 0.0746
Echinococcus granulosus contactin 0.0025 0.0015 0.0013
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0054 0.0099 0.0099
Onchocerca volvulus 0.0231 0.0601 0.1507
Loa Loa (eye worm) hypothetical protein 0.0223 0.0577 0.1088
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0124 0.0123
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0254 0.0666 0.0664
Brugia malayi sulfakinin receptor protein 0.0231 0.0601 0.1032
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0035
Echinococcus granulosus hypothetical protein 0.0031 0.0032 0.003
Echinococcus granulosus tm gpcr rhodopsin 0.0231 0.0601 0.06
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0045 0.0494
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.03 0.0303
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0075 0.0157 0.0459
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0031 0.0032 0.0054
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0231 0.0601 0.06
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0254 0.0666 0.1947
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0956 0.2661 0.4569
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0046 0.0113
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0075 0.0157 0.0459
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0254 0.0666 0.0664
Echinococcus multilocularis sodium and chloride dependent glycine 0.0108 0.0253 0.0252
Loa Loa (eye worm) ion channel NompC 0.0031 0.0032 0.006
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0075 0.0157 0.0589
Toxoplasma gondii hypothetical protein 0.0108 0.0253 0.0737
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0231 0.0601 0.0609
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0254 0.0666 0.2502
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Brugia malayi CXXC zinc finger family protein 0.0028 0.0023 0.004
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0026 0.0019 0.0018
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0031 0.0032 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0024 0.0057
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0254 0.0666 0.0664
Brugia malayi Cytochrome P450 family protein 0.0101 0.0232 0.0398
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0049 0.0084 0.0145
Loa Loa (eye worm) hypothetical protein 0.0034 0.0041 0.0078
Onchocerca volvulus 0.0231 0.0601 0.1507
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0204 0.0524 0.0556
Schistosoma mansoni hypothetical protein 0.0395 0.1067 0.1082
Loa Loa (eye worm) DR-78 0.0023 0.001 0.002
Schistosoma mansoni voltage-gated potassium channel 0.0187 0.0476 0.0482
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.018 0.0455 0.0482
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0254 0.0666 0.1666
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0108 0.0253 0.0255
Schistosoma mansoni amine GPCR 0.0231 0.0601 0.0609
Onchocerca volvulus 0.0023 0.001 0.0026
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0046 0.0077 0.0076
Schistosoma mansoni amine GPCR 0.0231 0.0601 0.0609
Schistosoma mansoni microtubule-associated protein tau 0.3487 0.985 1
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0075 0.0157 0.0459
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trypanosoma cruzi target of rapamycin kinase 3 0.0143 0.0351 0.0372
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0207
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0108 0.0253 0.0252
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0204 0.0524 0.0556
Echinococcus granulosus tyrosine protein kinase Src64B 0.0046 0.0077 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0024 0.0057
Loa Loa (eye worm) nuclear receptor NHR-67 0.0023 0.001 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0041 0.01
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0956 0.2661 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0536 0.1467 0.252
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0124 0.0233
Echinococcus granulosus sex peptide receptor 0.0231 0.0601 0.06
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0075 0.0157 0.0165
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0114 0.0112
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0035
Schistosoma mansoni hypothetical protein 0.0026 0.0019 0.0018
Brugia malayi Inositol-1 0.0186 0.0472 0.0811
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0254 0.0666 0.2059
Loa Loa (eye worm) TOPoisomerase family member 0.0078 0.0167 0.0315
Echinococcus multilocularis transient receptor potential cation channel 0.0031 0.0032 0.003
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0108 0.0402
Toxoplasma gondii 6-phosphofructokinase 0.006 0.0115 0.0334
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0084 0.0084
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0054 0.0099 0.0099
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0075 0.0157 0.0165
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.007 0.0142 0.0414
Echinococcus multilocularis para nitrobenzyl esterase 0.0058 0.011 0.0108
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0034 0.0041 0.0042
Echinococcus granulosus serine protein kinase ATM 0.0034 0.0041 0.004
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.018 0.0456 0.0462
Echinococcus granulosus biogenic amine 5HT receptor 0.06 0.1649 0.1648
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0085 0.0187 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0117 0.0276 0.0689
Onchocerca volvulus 0.0106 0.0247 0.0619
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0049 0.0084 0.0083
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0034 0.0041 0.0454
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0031 0.0032 0.0089
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0024 0.0012 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0075 0.0157 0.0459
Onchocerca volvulus 0.0109 0.0254 0.0637
Entamoeba histolytica hypothetical protein 0.0035 0.0045 0.0494
Trichomonas vaginalis phosphofructokinase, putative 0.0222 0.0575 0.144
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0037 0.0049 0.0048
Onchocerca volvulus 0.0265 0.0698 0.1749
Brugia malayi Carboxylesterase family protein 0.0058 0.011 0.0188
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0108 0.0186
Schistosoma mansoni hypothetical protein 0.0024 0.0012 0.0011
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0046 0.0048
Echinococcus granulosus rhodopsin orphan GPCR 0.0231 0.0601 0.06
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0207
Treponema pallidum quinoline 2-oxidoreductase 0.0106 0.0247 0.0926
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Toxoplasma gondii phosphofructokinase PFKII 0.006 0.0115 0.0334
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0024 0.0012 0.0011
Toxoplasma gondii LsmAD domain-containing protein 0.0101 0.0231 0.0673
Schistosoma mansoni hypothetical protein 0.0035 0.0045 0.0044
Schistosoma mansoni hypothetical protein 0.003 0.0029 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0106 0.0246 0.0615
Loa Loa (eye worm) hypothetical protein 0.0063 0.0124 0.0234
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.0006 0.0005
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0046 0.0077 0.0076
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0254 0.0666 0.7406
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0006 0.0005
Schistosoma mansoni hypothetical protein 0.0075 0.0157 0.0158
Echinococcus multilocularis ryanodine receptor 44f 0.0031 0.0032 0.003
Echinococcus granulosus ecdysone induced protein 78C 0.0049 0.0084 0.0083
Brugia malayi Carboxylesterase family protein 0.0058 0.011 0.0188
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0316 0.0841 0.3162
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0046 0.0077 0.0076
Schistosoma mansoni adrenodoxin 0.0022 0.0006 0.0005
Echinococcus multilocularis inositol monophosphatase 1 0.0186 0.0472 0.0471
Schistosoma mansoni retinoic acid receptor RXR 0.0049 0.0084 0.0084
Brugia malayi Probable DNA topoisomerase II 0.0078 0.0167 0.0287
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0254 0.0666 0.0664
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0034 0.0041 0.004
Trichomonas vaginalis glutamate synthase, putative 0.0254 0.0666 0.1666
Loa Loa (eye worm) RNA binding protein 0.0062 0.0121 0.0229
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0031 0.0032 0.003
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0254 0.0666 0.1666
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0075 0.0157 0.0165
Schistosoma mansoni hypothetical protein 0.0035 0.0045 0.0044
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0024 0.0012 0.0011
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.001 0.0009
Echinococcus granulosus potassium voltage gated channel protein 0.0031 0.0032 0.003
Echinococcus granulosus rhodopsin orphan GPCR 0.0231 0.0601 0.06
Echinococcus multilocularis G-protein coupled receptor, putative 0.0231 0.0601 0.06
Echinococcus granulosus potassium voltage gated channel protein 0.0031 0.0032 0.003
Echinococcus multilocularis Immunoglobulin 0.0051 0.0091 0.009
Echinococcus granulosus two pore calcium channel protein 1 0.0031 0.0032 0.003
Onchocerca volvulus 0.0231 0.0601 0.1507
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0038 0.0053 0.0131
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0054 0.0099 0.0249
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0024 0.0012 0.0031
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Echinococcus granulosus somatostatin receptor 0.0231 0.0601 0.06
Treponema pallidum hypothetical protein 0.009 0.0199 0.0748
Schistosoma mansoni survival motor neuron protein 0.0244 0.0637 0.0646
Onchocerca volvulus Bile acid receptor homolog 0.0049 0.0084 0.0211
Echinococcus multilocularis neuropeptide Y receptor 0.0231 0.0601 0.06
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0063 0.0124 0.0311
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143 0.035 0.0876
Echinococcus multilocularis g protein coupled receptor 0.0231 0.0601 0.06
Loa Loa (eye worm) voltage-gated potassium channel 0.0031 0.0032 0.006
Onchocerca volvulus 0.0231 0.0601 0.1507
Plasmodium vivax 6-phosphofructokinase, putative 0.006 0.0115 0.0334
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0204 0.0524 0.0556
Echinococcus granulosus glutamate synthase 0.0254 0.0666 0.0664
Leishmania major ferredoxin, 2fe-2s-like protein 0.0022 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0639 0.176 0.332
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0031 0.0032 0.0054
Schistosoma mansoni chromobox protein 0.0094 0.0212 0.0214
Echinococcus granulosus chromobox protein 2 0.0035 0.0045 0.0044
Entamoeba histolytica ABC transporter, putative 0.0036 0.0046 0.0504
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0231 0.0601 0.0609
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0046 0.0045
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0254 0.0666 0.195
Echinococcus granulosus neuropeptide receptor 0.0231 0.0601 0.06
Echinococcus multilocularis allatostatin A receptor 0.0231 0.0601 0.06
Brugia malayi hypothetical protein 0.0058 0.011 0.0188
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0434
Echinococcus granulosus tumor protein p63 0.1024 0.2853 0.2852
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0031 0.0032 0.003
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0031 0.0032 0.0054
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0042 0.0063 0.0154
Trichomonas vaginalis glucosylceramidase, putative 0.0505 0.1379 0.3456
Echinococcus granulosus defective proboscis extension response 0.0051 0.0091 0.009
Brugia malayi Doublecortin family protein 0.0159 0.0396 0.0679
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0956 0.2661 0.7793
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0524 0.1312
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0434
Trichomonas vaginalis chromobox protein, putative 0.0066 0.0133 0.033
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0226 0.0587 0.2205
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0054 0.0099 0.0099
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0051 0.0091 0.0091
Treponema pallidum NADH oxidase 0.0956 0.2661 1
Brugia malayi Cytochrome P450 family protein 0.0075 0.0157 0.0269
Brugia malayi voltage-dependent calcium channel 0.0031 0.0032 0.0054
Schistosoma mansoni neuropeptide f receptor 76f 0.0231 0.0601 0.0609
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0037 0.0049 0.0093
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0031 0.0032 0.003
Loa Loa (eye worm) calcium channel 0.0031 0.0032 0.006
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0075 0.0157 0.0459
Schistosoma mansoni cell adhesion molecule 0.0066 0.0131 0.0132
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Brugia malayi larval opioid receptor 0.0231 0.0601 0.1032
Echinococcus multilocularis neuropeptide receptor 0.0231 0.0601 0.06
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.001 0.0009
Echinococcus granulosus GPCR family 2 0.0047 0.0078 0.0077
Echinococcus multilocularis netrin receptor unc 5 0.005 0.0087 0.0086
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.0233 0.04
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0022 0.0006 0.0014
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0128 0.0308 0.1157
Trichomonas vaginalis inositol monophosphatase, putative 0.0186 0.0472 0.1181
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.018 0.0456 0.1332
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Brugia malayi MAP kinase sur-1 0.0204 0.0524 0.09
Brugia malayi hypothetical protein 0.0159 0.0396 0.0679
Brugia malayi SET domain containing protein 0.0042 0.0065 0.0112
Entamoeba histolytica disulphide oxidoreductase, putative 0.0254 0.0666 0.7406
Onchocerca volvulus 0.0159 0.0396 0.0991
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0085 0.0187 0.0322
Schistosoma mansoni neuropeptide F-like receptor 0.0231 0.0601 0.0609
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0031 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.1471 0.4124 0.778
Brugia malayi G protein-coupled receptor 0.0231 0.0601 0.1032
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0254 0.0666 0.2502
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0187 0.0476 0.0474
Mycobacterium ulcerans hypothetical protein 0.0109 0.0254 0.0954
Brugia malayi steroid hormone receptor 0.0049 0.0084 0.0145
Brugia malayi Carboxylesterase family protein 0.0058 0.011 0.0188
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0054 0.0099 0.0098
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0031 0.0032 0.003
Trichomonas vaginalis xanthine dehydrogenase, putative 0.067 0.1846 0.4627
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0173 0.0435 0.0434
Brugia malayi intermediate filament protein 0.0106 0.0247 0.0424
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0084 0.0145
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0022 0.0006 0.0017
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0108 0.0317
Schistosoma mansoni hypothetical protein 0.0244 0.0637 0.0646
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0075 0.0157 0.0459
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.007 0.0142 0.0141
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0038 0.0052 0.0149
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0231 0.0601 0.06
Echinococcus multilocularis orexin receptor type 2 0.0231 0.0601 0.06
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0186 0.0472 0.1772
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0026 0.0018 0.0017
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0022 0.0006 0.0017
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2808 0.7919 0.8422
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0186 0.0472 0.1381
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0956 0.2661 0.266
Plasmodium falciparum thioredoxin reductase 0.0956 0.2661 0.7793
Echinococcus multilocularis sodium and chloride dependent glycine 0.0108 0.0253 0.0252
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.018 0.0456 0.0455
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0031 0.0032 0.003
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0075 0.0157 0.0589
Leishmania major hypothetical protein, conserved 0.0024 0.0012 0.0011
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0231 0.0601 0.0609
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0035
Brugia malayi hypothetical protein 0.0108 0.0253 0.0434
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0024 0.0012 0.0031
Brugia malayi G protein-coupled receptor F59B2.13 0.0231 0.0601 0.1032
Echinococcus multilocularis neuropeptide receptor A26 0.1158 0.3234 0.3233
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0031 0.0032 0.0031
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0015 0.0014
Schistosoma mansoni bromodomain containing protein 0.0067 0.0135 0.0135
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0024 0.0012 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0075 0.0157 0.0459
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0187 0.0476 0.0482
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0031 0.0032 0.003
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0037 0.0049 0.0051
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.0036
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0477
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Trichomonas vaginalis adenylate cyclase, putative 0.0038 0.0053 0.0131
Echinococcus granulosus neuropeptides capa receptor 0.0231 0.0601 0.06
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0053 0.0131
Brugia malayi GnHR receptor homolog 0.0231 0.0601 0.1032
Brugia malayi bZIP transcription factor family protein 0.0338 0.0904 0.1553
Echinococcus granulosus cpg binding protein 0.0031 0.0034 0.0032
Treponema pallidum thioredoxin reductase (trxB) 0.0254 0.0666 0.25
Trichomonas vaginalis glucosylceramidase, putative 0.0505 0.1379 0.3456
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0075 0.0157 0.0459
Brugia malayi N-terminal motif family protein 0.0206 0.0529 0.0909
Echinococcus multilocularis Ankyrin 0.0042 0.0065 0.0063
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1175 0.3283 0.3282
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0455 0.1238 0.3627
Brugia malayi G-protein coupled receptor 0.0231 0.0601 0.1032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0324 0.081
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0031 0.0032 0.0031
Schistosoma mansoni transient receptor potential channel 0.0031 0.0032 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Loa Loa (eye worm) hypothetical protein 0.0108 0.0253 0.0477
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0254 0.0666 0.0707
Trypanosoma cruzi hypothetical protein, conserved 0.0254 0.0666 0.0707
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0078 0.0077
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0031 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0159 0.0396 0.0746
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0121 0.0122
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0054 0.0099 0.0249
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0038 0.0053 0.0131
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.0066 0.0065
Plasmodium vivax 6-phosphofructokinase, putative 0.006 0.0115 0.0334
Schistosoma mansoni neuropeptide receptor 0.0231 0.0601 0.0609
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Entamoeba histolytica protein kinase, putative 0.0039 0.0055 0.0607
Schistosoma mansoni single-minded 0.0147 0.0363 0.0367
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0018 0.0032
Entamoeba histolytica protein kinase rad3, putative 0.0034 0.0041 0.0454
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0001 0.0002
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0036 0.0046 0.0047
Onchocerca volvulus 0.0038 0.0053 0.0134
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0231 0.0601 0.0609
Loa Loa (eye worm) hypothetical protein 0.002 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0231 0.0601 0.0609
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0054 0.0133
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0049 0.0084 0.0083
Brugia malayi cation channel family protein 0.0031 0.0032 0.0054
Mycobacterium ulcerans DNA gyrase subunit B 0.002 0.0001 0.0005
Echinococcus granulosus patatin phospholipase domain containing protein 0.0024 0.0012 0.0011
Onchocerca volvulus 0.0108 0.0253 0.0634
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0024 0.0012 0.0027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0254 0.0666 0.0707
Entamoeba histolytica phosphofructokinase, putative 0.0222 0.0575 0.64
Brugia malayi hypothetical protein 0.0035 0.0045 0.0077
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.03 0.0299
Echinococcus granulosus voltage gated hydrogen channel 1 0.0031 0.0032 0.003
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0022 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0956 0.2661 1
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0254 0.0666 0.0664
Loa Loa (eye worm) hypothetical protein 0.0051 0.0091 0.0172
Echinococcus granulosus tachykinin peptides receptor 99D 0.0231 0.0601 0.06
Trichomonas vaginalis Ferredoxin 6 0.0022 0.0006 0.0012
Brugia malayi tailless protein 0.0023 0.001 0.0018
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0078 0.0077
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0338 0.0904 0.0903
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0042 0.0063 0.0154
Brugia malayi TAR-binding protein 0.0062 0.0121 0.0208
Leishmania major NADH dehydrogenase, putative 0.0254 0.0666 0.0707
Echinococcus multilocularis voltage gated potassium channel 0.0031 0.0032 0.003
Schistosoma mansoni 60S ribosomal protein L21 0.0044 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.022 0.0549
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0036 0.0046 0.013
Echinococcus multilocularis two pore calcium channel protein 1 0.0031 0.0032 0.003
Trichomonas vaginalis Ferredoxin 7 0.0022 0.0006 0.0012
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0956 0.2661 0.7793
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.006 0.0116 0.0122
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0204 0.0524 0.0556
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0231 0.0601 0.0609
Echinococcus granulosus zinc finger protein 0.0022 0.0007 0.0005
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0336 0.0899 1
Chlamydia trachomatis endonuclease IV 0.0074 0.0155 0.0578
Trichomonas vaginalis mercuric reductase, putative 0.0956 0.2661 0.6669
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1158 0.3233 1
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0046 0.0077 0.0076
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0038 0.0053 0.0052
Loa Loa (eye worm) phosphofructokinase 0.0222 0.0575 0.1085
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0024 0.0012 0.002
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0024 0.0012 0.0011
Echinococcus multilocularis tyrosine protein kinase HCK 0.0039 0.0055 0.0054
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0956 0.2661 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0254 0.0666 0.1947
Brugia malayi ecdysteroid receptor 0.0049 0.0084 0.0145
Echinococcus granulosus allatostatin A receptor 0.0231 0.0601 0.06
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0956 0.2661 0.2829
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.022 0.0549
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0058 0.011 0.011
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0023 0.001 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.0222 0.0575 0.144
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0075 0.0157 0.0459
Onchocerca volvulus 0.0108 0.0253 0.0634
Trichomonas vaginalis glucosylceramidase, putative 0.077 0.2131 0.5341
Echinococcus granulosus sodium leak channel non selective protein 0.0031 0.0032 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0017 0.0016
Brugia malayi Intermediate filament tail domain containing protein 0.0106 0.0247 0.0424
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0031 0.0032 0.0054
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.018 0.0455 0.0482
Loa Loa (eye worm) hypothetical protein 0.0042 0.0064 0.012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0049 0.0084 0.0159
Brugia malayi AKH receptor 0.0231 0.0601 0.1032
Schistosoma mansoni hypothetical protein 0.0031 0.0032 0.0031
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0031 0.0032 0.003
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0536 0.1467 0.1489
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0031 0.0032 0.0031
Brugia malayi Melatonin receptor type 1A 0.0231 0.0601 0.1032
Loa Loa (eye worm) hypothetical protein 0.015 0.037 0.0699
Onchocerca volvulus 0.0231 0.0601 0.1507
Loa Loa (eye worm) hypothetical protein 0.0536 0.1467 0.2768
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0025 0.0017 0.0046
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0206 0.0529 0.1326
Leishmania major ferredoxin 2fe-2s-like protein 0.0022 0.0006 0.0005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0231 0.0601 0.06
Trichomonas vaginalis PIKK family atypical protein kinase 0.0153 0.038 0.095
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0132 0.0318 0.0337
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.018 0.0456 0.0455
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0054 0.0099 0.0099
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0034 0.0041 0.0071
Trichomonas vaginalis chromobox protein, putative 0.0066 0.0133 0.033
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0024 0.0012 0.0031
Loa Loa (eye worm) hypothetical protein 0.0639 0.176 0.332
Onchocerca volvulus 0.0231 0.0601 0.1507
Brugia malayi Fibronectin type III domain containing protein 0.0057 0.0107 0.0184
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0231 0.0601 0.1134
Loa Loa (eye worm) hypothetical protein 0.0108 0.0253 0.0477
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0159
Treponema pallidum hypothetical protein 0.0109 0.0254 0.0953
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0042 0.0064 0.012
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Onchocerca volvulus 0.0058 0.011 0.0275
Trypanosoma cruzi hypothetical protein, conserved 0.0254 0.0666 0.0707
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0096 0.0216 0.2401
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0231 0.0601 0.06
Schistosoma mansoni apoptosis regulator bax 0.0085 0.0187 0.0189
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0106 0.0247 0.0466
Schistosoma mansoni hypothetical protein 0.0103 0.0238 0.0241
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0042 0.0064 0.0062
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0078 0.0167 0.0287
Brugia malayi hypothetical protein 0.0023 0.001 0.0018
Treponema pallidum cyclic nucleotide binding protein 0.0024 0.0012 0.0043
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0254 0.0666 0.0707
Loa Loa (eye worm) programmed cell death 8 0.0254 0.0666 0.1256
Plasmodium falciparum heterochromatin protein 1 0.0035 0.0045 0.0128
Echinococcus multilocularis carboxylesterase 5A 0.0344 0.0921 0.092
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0024 0.0012 0.0011
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.006 0.0115 0.0334
Schistosoma mansoni amine GPCR 0.1886 0.5301 0.5381
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0031 0.0032 0.0054
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.006 0.0116 0.0122
Schistosoma mansoni nuclear receptor 0.0023 0.001 0.0009
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2808 0.7919 0.8422
Leishmania major phosphatidylinositol 3-related kinase, putative 0.006 0.0116 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0054 0.0133
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0186 0.0472 0.1181
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0231 0.0601 0.06
Echinococcus granulosus tar DNA binding protein 0.0062 0.0121 0.012
Echinococcus multilocularis Protein lozenge 0.0058 0.011 0.0109
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0254 0.0666 0.0707
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0121 0.012
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0035 0.0045 0.0128
Loa Loa (eye worm) cytochrome P450 family protein 0.0101 0.0232 0.0438
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0031 0.0032 0.0031
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0147 0.0363 0.1122
Brugia malayi Egg laying defective protein 4 0.0025 0.0017 0.0029
Trypanosoma cruzi cAMP response protein 1 0.0024 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0344 0.0921 0.1738
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Giardia lamblia DNA topoisomerase II 0.0074 0.0156 0.0583
Schistosoma mansoni transient receptor potential channel 0.0031 0.0033 0.0032
Echinococcus multilocularis potassium large conductance calcium activated 0.0031 0.0032 0.003
Onchocerca volvulus 0.0058 0.011 0.0275
Loa Loa (eye worm) glutaminase 0.0267 0.0704 0.1328
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0035 0.0045 0.0128
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Loa Loa (eye worm) hypothetical protein 0.0057 0.0107 0.0203
Echinococcus multilocularis transient receptor potential cation channel 0.0031 0.0033 0.0031
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0038 0.0053 0.0131
Giardia lamblia Fructose-bisphosphate aldolase 0.0301 0.0801 0.3006
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.006 0.0115 0.0428
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0108 0.0253 0.0737
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Entamoeba histolytica hypothetical protein 0.0034 0.0041 0.0454
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0124 0.0308
Giardia lamblia Glutamate synthase 0.0254 0.0666 0.2498
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0001 0.0009
Echinococcus granulosus sodium and chloride dependent glycine 0.0108 0.0253 0.0252
Mycobacterium ulcerans oxidoreductase 0.0022 0.0006 0.0022
Brugia malayi neuropeptide F receptor 0.0231 0.0601 0.1032
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0231 0.0673
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0143 0.035 0.0875
Echinococcus granulosus biogenic amine 5HT receptor 0.0595 0.1634 0.1633
Echinococcus granulosus alpha 1A adrenergic receptor 0.0231 0.0601 0.06
Plasmodium vivax ataxin-2 like protein, putative 0.0101 0.0231 0.0673
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Echinococcus granulosus short transient receptor potential channel 6 0.0031 0.0033 0.0031
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0085
Loa Loa (eye worm) SRC-1 0.0046 0.0077 0.0145
Giardia lamblia Kinase, CMGC MAPK 0.0204 0.0524 0.1967
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0074 0.0155 0.0454
Loa Loa (eye worm) hypothetical protein 0.0464 0.1264 0.2385
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0024 0.0012 0.0011
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0063 0.0154
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0222 0.0575 0.2161
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0024 0.0012 0.0011
Mycobacterium ulcerans 6-phosphofructokinase 0.0222 0.0575 0.2162
Echinococcus multilocularis ATP binding cassette sub family G 0.0036 0.0046 0.0044
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0023 0.0044
Trichomonas vaginalis DNA topoisomerase II, putative 0.0078 0.0167 0.0416
Brugia malayi nuclear receptor RXR 0.0026 0.0018 0.0032
Schistosoma mansoni ankyrin 23/unc44 0.0042 0.0064 0.0063
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0254 0.0666 0.0707
Brugia malayi follicle stimulating hormone receptor 0.0928 0.2581 0.4432
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0063 0.0154
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0001 0.0005
Schistosoma mansoni sodium/chloride dependent transporter 0.0108 0.0253 0.0255
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0116 0.0287
Echinococcus granulosus chromobox protein 1 0.0094 0.0212 0.0211
Schistosoma mansoni lozenge 0.0058 0.011 0.0111
Brugia malayi hypothetical protein 0.0023 0.001 0.0018
Echinococcus granulosus transient receptor potential cation channel 0.0031 0.0032 0.003
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0024 0.0012 0.0011
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0037 0.0049 0.0048
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1471 0.4124 0.4386
Loa Loa (eye worm) hypothetical protein 0.007 0.0145 0.0273
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0231 0.0601 0.06
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.006 0.0114 0.012
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trypanosoma cruzi DNA topoisomerase II, putative 0.0078 0.0167 0.0177
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0231 0.0601 0.06
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.018 0.0455 0.0482
Entamoeba histolytica hypothetical protein 0.0035 0.0045 0.0494
Giardia lamblia [2Fe-2S] ferredoxin 0.0022 0.0006 0.0017
Echinococcus granulosus jun protein 0.0338 0.0904 0.0903
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0036 0.0046 0.0172
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0045 0.0109
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0058 0.011 0.011
Echinococcus multilocularis dro:myosuppressin receptor 0.0231 0.0601 0.06
Trichomonas vaginalis glucosylceramidase, putative 0.0532 0.1457 0.3649
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Schistosoma mansoni hypothetical protein 0.0047 0.0078 0.0078
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0108 0.0253 0.0252
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0204 0.0524 0.0556
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.001 0.0026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Schistosoma mansoni inositol monophosphatase 0.0186 0.0472 0.0478
Echinococcus multilocularis microtubule associated protein 2 0.3487 0.985 0.985
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0244 0.0637 0.1094
Onchocerca volvulus 0.0244 0.0637 0.1596
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0024 0.0012 0.0011
Brugia malayi hypothetical protein 0.0031 0.0032 0.0054
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0254 0.0666 0.0707
Mycobacterium leprae Conserved hypothetical protein 0.0075 0.0157 0.0484
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0301 0.0801 0.891
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0124 0.0124
Schistosoma mansoni chromobox protein 0.0035 0.0045 0.0044
Schistosoma mansoni adenoreceptor 0.0231 0.0601 0.0609
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0254 0.0666 0.1666
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0045 0.0494
Schistosoma mansoni sodium/chloride dependent transporter 0.011 0.0258 0.0261
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0039 0.0055 0.0054
Schistosoma mansoni aryl hydrocarbon receptor 0.0147 0.0363 0.0367
Brugia malayi Steroid receptor seven-up type 2 0.0049 0.0084 0.0145
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0031 0.0032 0.0031
Mycobacterium ulcerans ferredoxin reductase 0.0254 0.0666 0.2502
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0049 0.0084 0.0083
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0075 0.0157 0.0589
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0108 0.0253 0.0255
Trypanosoma cruzi protein kinase A regulatory subunit 0.0024 0.0012 0.0011
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0026 0.0018 0.0017
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0254 0.0666 0.1947
Loa Loa (eye worm) hypothetical protein 0.0752 0.2081 0.3926
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.0038
Echinococcus multilocularis transient receptor potential cation channel 0.0031 0.0032 0.003
Schistosoma mansoni inositol monophosphatase 0.0186 0.0472 0.0478
Loa Loa (eye worm) carboxylesterase 0.0058 0.011 0.0207
Echinococcus granulosus netrin receptor unc 5 0.005 0.0087 0.0086
Echinococcus granulosus voltage dependent calcium channel 0.0031 0.0032 0.003
Toxoplasma gondii exonuclease III APE 0.0058 0.0108 0.0314
Trichomonas vaginalis PIKK family atypical protein kinase 0.018 0.0455 0.1137
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0078 0.0167 0.0166
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Echinococcus multilocularis acetylcholinesterase 0.0344 0.0921 0.092
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0254 0.0666 0.1666
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.006 0.0116 0.0116
Echinococcus multilocularis transcription factor Dp 1 0.0076 0.0161 0.016
Schistosoma mansoni 6-phosphofructokinase 0.0222 0.0575 0.0583
Echinococcus granulosus mitogen activated protein kinase 0.0204 0.0524 0.0523
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0143 0.0351 0.0372
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.03 0.1127
Echinococcus multilocularis neuropeptide FF receptor 2 0.0231 0.0601 0.06
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0231 0.0601 0.0609
Schistosoma mansoni hypothetical protein 0.0855 0.2373 0.2409
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0207
Echinococcus granulosus serotonin transporter 0.0639 0.176 0.1759
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0241 0.0629 0.0628
Leishmania major cytochrome p450-like protein 0.0075 0.0157 0.0165
Schistosoma mansoni acetylcholinesterase 0.0058 0.011 0.011
Brugia malayi hypothetical protein 0.0026 0.0018 0.0032
Loa Loa (eye worm) hepatopoietin HPO2 0.007 0.0142 0.0269
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.018 0.0455 0.0454
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0338 0.0904 0.0903
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0072 0.0123
Leishmania major C-8 sterol isomerase-like protein 0.1471 0.4124 0.4386
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.018 0.0456 0.1716
Onchocerca volvulus 0.0231 0.0601 0.1507
Schistosoma mansoni rab6-interacting 0.0159 0.0396 0.04
Echinococcus granulosus carboxylesterase 5A 0.0344 0.0921 0.092
Echinococcus granulosus cGMP dependent protein kinase 1 0.0025 0.0017 0.0016
Mycobacterium ulcerans hypothetical protein 0.0254 0.0666 0.2502
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0134 0.0324 0.081
Leishmania major protein kinase, putative 0.0064 0.0126 0.0132
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0085 0.0186 0.0196
Trypanosoma cruzi trypanothione reductase, putative 0.0956 0.2661 0.2829
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0024 0.0012 0.0031
Trypanosoma brucei ATP-binding cassette protein, putative 0.0036 0.0046 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Schistosoma mansoni hypothetical protein 0.0045 0.0073 0.0073
Schistosoma mansoni DNA topoisomerase II 0.0078 0.0167 0.0169
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0031 0.0032 0.0054
Echinococcus multilocularis roundabout 2 0.0066 0.0131 0.013
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0068 0.0138 0.0136
Brugia malayi Immunoglobulin I-set domain containing protein 0.0057 0.0107 0.0184
Loa Loa (eye worm) hypothetical protein 0.0108 0.0253 0.0477
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0074 0.0155 0.0292
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Brugia malayi cation channel family protein 0.0031 0.0032 0.0054
Schistosoma mansoni cytochrome P450 0.0075 0.0157 0.0158
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0051 0.0091 0.0091
Echinococcus multilocularis Immunoglobulin 0.0051 0.0091 0.009
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0085
Plasmodium vivax SET domain protein, putative 0.018 0.0456 0.1332
Brugia malayi bHLH-PAS transcription factor 0.0109 0.0254 0.0436
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0072 0.007
Loa Loa (eye worm) blistered cuticle protein 3 0.0146 0.036 0.068
Echinococcus granulosus lamin 0.0106 0.0247 0.0246
Trichomonas vaginalis Ferredoxin 3 0.0022 0.0006 0.0012
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.006 0.0115 0.1276
Schistosoma mansoni hypothetical protein 0.0231 0.0601 0.0609
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0801 0.2005
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0108 0.0253 0.0252
Chlamydia trachomatis ferredoxin 0.0022 0.0006 0.0017
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0108 0.0314
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0045 0.0109
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0204 0.0524 0.0989
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.004 0.0059 0.0061
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0075 0.0157 0.0589
Loa Loa (eye worm) hypothetical protein 0.0054 0.0099 0.0186
Onchocerca volvulus 0.0022 0.0006 0.0015
Trichomonas vaginalis glutaminase, putative 0.0267 0.0704 0.1762
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0078 0.0134
Schistosoma mansoni glutaminase 0.0267 0.0704 0.0713
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0031 0.0032 0.0054
Trichomonas vaginalis glutamate synthase, putative 0.0254 0.0666 0.1666
Echinococcus granulosus roundabout 2 0.0066 0.0131 0.013
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0132 0.0318 0.0322
Trichomonas vaginalis glutathione reductase, putative 0.0956 0.2661 0.6669
Echinococcus granulosus neuropeptide FF receptor 2 0.0231 0.0601 0.06
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0254 0.0666 0.0707
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0075 0.0157 0.0589
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0024 0.0012 0.0035
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0254 0.0666 0.195
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.007 0.0142 0.015
Loa Loa (eye worm) hypothetical protein 0.0052 0.0091 0.0172
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0254 0.0666 0.1666
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0108 0.0253 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0008 0.0018
Loa Loa (eye worm) hypothetical protein 0.0051 0.0091 0.0172
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0031 0.0032 0.0031
Brugia malayi Dopamine receptor protein 2 0.0231 0.0601 0.1032
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0207
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0455 0.1238 0.3627
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.2808 0.7919 0.8422
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0254 0.0666 0.0707
Schistosoma mansoni hypothetical protein 0.0047 0.0078 0.0078
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0012 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0106 0.0246 0.0615
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0595 0.1634 0.1633
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0068 0.0138 0.0236
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0024 0.0012 0.0011
Loa Loa (eye worm) helicase 0.0035 0.0045 0.0085
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0022 0.0006 0.0005
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0124 0.0123
Brugia malayi nuclear hormone receptor family member odr-7 0.0023 0.001 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Schistosoma mansoni chromobox protein 0.0094 0.0212 0.0214
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0042 0.0065 0.0064
Toxoplasma gondii target of rapamycin (TOR), putative 0.0134 0.0324 0.0946
Loa Loa (eye worm) carboxylesterase 0.0058 0.011 0.0207
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0084 0.0145
Brugia malayi PAS domain containing protein 0.0147 0.0363 0.0623
Mycobacterium ulcerans NADH dehydrogenase 0.0254 0.0666 0.2502
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.007 0.0142 0.0414
Echinococcus multilocularis tumor protein p63 0.1024 0.2853 0.2852
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0054 0.0099 0.0098
Loa Loa (eye worm) hypothetical protein 0.0639 0.176 0.332
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0046 0.0045
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0231 0.0601 0.06
Brugia malayi Thioredoxin reductase 0.1221 0.3414 0.5863
Echinococcus granulosus death domain containing protein 0.0042 0.0064 0.0062
Mycobacterium tuberculosis Conserved hypothetical protein 0.0024 0.0012 0.0035
Echinococcus multilocularis serotonin transporter 0.0639 0.176 0.1759
Trichomonas vaginalis PIKK family atypical protein kinase 0.018 0.0455 0.1137
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0254 0.0666 0.195
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0222 0.0575 0.1685
Brugia malayi hypothetical protein 0.0249 0.0651 0.1119
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.006 0.0116 0.0115
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0143 0.0351 0.0372
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.007 0.0142 0.015
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.0366 0.0629
Schistosoma mansoni lipoxygenase 0.0412 0.1114 0.113
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.0006 0.0005
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0035 0.0045 0.0128
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0049 0.0084 0.0145
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0702 0.194 0.3331
Loa Loa (eye worm) phosphatidylinositol 3 0.006 0.0116 0.0218
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0015 0.0014
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0037 0.0049 0.0093
Brugia malayi M-phase phosphoprotein, mpp8 0.0222 0.0576 0.0989
Loa Loa (eye worm) hypothetical protein 0.0159 0.0396 0.0746
Loa Loa (eye worm) hypothetical protein 0.06 0.1649 0.3111
Echinococcus granulosus neuropeptide receptor A26 0.1158 0.3234 0.3233
Loa Loa (eye worm) RecQ helicase 0.0021 0.0004 0.0008
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0046 0.0045
Toxoplasma gondii Erv1 / Alr family protein 0.007 0.0142 0.0414
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0231 0.0601 0.0609
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0231 0.0601 0.1134
Onchocerca volvulus 0.0222 0.0576 0.1443
Onchocerca volvulus 0.0231 0.0601 0.1507
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0254 0.0666 0.7406
Loa Loa (eye worm) hypothetical protein 0.1886 0.5301 1
Echinococcus granulosus Chromo domain 0.0035 0.0045 0.0044
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0254 0.0666 0.2502
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0054 0.0099 0.0245
Loa Loa (eye worm) hypothetical protein 0.0329 0.0878 0.1656
Plasmodium falciparum cGMP-dependent protein kinase 0.0025 0.0017 0.0046
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0023 0.001 0.0018
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1251 0.3498 0.66
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0186 0.0472 0.0501
Echinococcus granulosus tyrosine protein kinase Lyn 0.0048 0.0082 0.0081
Echinococcus granulosus rhodopsin orphan GPCR 0.0231 0.0601 0.06
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0072 0.0135
Onchocerca volvulus 0.0231 0.0601 0.1507
Leishmania major hypothetical protein, conserved 0.0254 0.0666 0.0707
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0045 0.0128
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0231 0.0601 0.0609
Echinococcus granulosus sodium and chloride dependent glycine 0.0108 0.0253 0.0252
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0026 0.0018 0.0035
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0054 0.0099 0.0249
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0084 0.0084
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0698 0.1926 0.1925
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0075 0.0157 0.0459
Mycobacterium tuberculosis Probable dehydrogenase 0.0455 0.1238 0.3627
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.022 0.0548
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0045 0.0128
Echinococcus granulosus twitchin 0.0053 0.0096 0.0095
Onchocerca volvulus 0.0058 0.011 0.0275
Schistosoma mansoni voltage-gated ion channel 0.0031 0.0032 0.0031
Plasmodium falciparum ABC transporter G family member 2 0.0036 0.0046 0.013
Trichomonas vaginalis hypothetical protein 0.0035 0.0045 0.0109
Schistosoma mansoni hypothetical protein 0.0085 0.0187 0.0189
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.006
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.006 0.0116 0.0122
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0085 0.0187 0.0186
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0115 0.0285
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0108 0.0253 0.0252
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0254 0.0666 0.7406
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0049 0.0084 0.0159
Brugia malayi putative neuropeptide receptor 0.0231 0.0601 0.1032
Echinococcus granulosus rhodopsin orphan GPCR 0.0231 0.0601 0.06
Mycobacterium tuberculosis Probable oxidoreductase 0.0022 0.0006 0.0017
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0054 0.0099 0.0186
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0231 0.0601 0.0609
Schistosoma mansoni calcium-activated potassium channel 0.0031 0.0032 0.0031
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0231 0.0601 0.06
Echinococcus granulosus orexin receptor type 2 0.0231 0.0601 0.06
Treponema pallidum sodium- and chloride- dependent transporter 0.0639 0.176 0.6613
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.0524 0.1312
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0075 0.0157 0.0459
Leishmania major hypothetical protein, conserved 0.0031 0.0032 0.0032
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0231 0.0601 0.06
Loa Loa (eye worm) hypothetical protein 0.015 0.037 0.0698
Leishmania major hypothetical protein, conserved 0.0022 0.0006 0.0005
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0204 0.0524 0.0556
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0075 0.0157 0.0459
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0072 0.007
Schistosoma mansoni tyrosine kinase 0.0046 0.0077 0.0077
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0075 0.0157 0.0165
Loa Loa (eye worm) hypothetical protein 0.0085 0.0187 0.0353
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0956 0.2661 0.7793
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.006 0.0116 0.0122
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0121 0.0229
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0108 0.0253 0.0255
Onchocerca volvulus 0.015 0.037 0.0928
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0075 0.0157 0.0165
Loa Loa (eye worm) AGC/PKG protein kinase 0.0025 0.0017 0.0032
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0186 0.0472 0.1181
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0024 0.0012 0.0011
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0121 0.0229
Schistosoma mansoni two-pore calcium channel 0.0031 0.0032 0.0031
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0026 0.0018 0.0017
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0031 0.0032 0.0079
Giardia lamblia GTOR 0.018 0.0455 0.1705
Schistosoma mansoni coup transcription factor 0.0049 0.0084 0.0084
Echinococcus multilocularis geminin 0.0855 0.2373 0.2373
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.03 0.1127
Echinococcus granulosus dnaJ subfamily B 0.0395 0.1067 0.1066
Echinococcus granulosus fmrfamide receptor 0.0231 0.0601 0.06
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0956 0.2661 0.27
Echinococcus granulosus sodium channel protein 0.0241 0.0629 0.0628
Mycobacterium ulcerans glutamate synthase subunit beta 0.0254 0.0666 0.2502
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0037 0.0049 0.0141
Schistosoma mansoni voltage-gated cation channel 0.0031 0.0032 0.0031
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0222 0.0575 0.0611
Echinococcus granulosus G protein coupled receptor 139 0.0231 0.0601 0.06
Schistosoma mansoni opsin-like receptor 0.0231 0.0601 0.0609
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0031 0.0032 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.333 0.9402 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0046 0.0077 0.0076
Echinococcus granulosus neuroglian 0.0051 0.0091 0.009
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0254 0.0666 0.0707
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0077 0.0076
Echinococcus multilocularis hyperpolarization activated cyclic 0.0054 0.0099 0.0098
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0132 0.0318 0.0337
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0024 0.0012 0.0011
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0108 0.0253 0.0946
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0108 0.0253 0.0252
Echinococcus multilocularis conserved hypothetical protein 0.0031 0.0032 0.003
Plasmodium falciparum ferredoxin, putative 0.0022 0.0006 0.0014
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0231 0.0601 0.0609
Echinococcus multilocularis rhodopsin orphan GPCR 0.0231 0.0601 0.06
Loa Loa (eye worm) hypothetical protein 0.006 0.0114 0.0216
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0024 0.0012 0.0011
Brugia malayi nuclear receptor NHR-88 0.0023 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0108 0.12
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0108 0.0107
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0038 0.0053 0.0055
Onchocerca volvulus 0.1424 0.399 1
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.002 0.0001 0.0004
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0254 0.0666 0.1143
Entamoeba histolytica thioredoxin reductase, putative 0.0254 0.0666 0.7406
Trichomonas vaginalis 6-phosphofructokinase, putative 0.006 0.0115 0.0285
Echinococcus granulosus aryl hydrocarbon receptor 0.0038 0.0053 0.0052
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0231 0.0601 0.06
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0075 0.0157 0.0589
Echinococcus granulosus chromobox protein 1 0.0094 0.0212 0.0211
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0034 0.0041 0.004
Echinococcus multilocularis two pore calcium channel protein 2 0.0031 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.002
Onchocerca volvulus 0.0031 0.0032 0.0079
Brugia malayi nuclear receptor RXR 0.0023 0.001 0.0018
Trypanosoma cruzi trypanothione reductase, putative 0.1221 0.3414 0.363
Schistosoma mansoni opsin-like receptor 0.0231 0.0601 0.0609
Echinococcus granulosus 7TM GPCR rhodopsin 0.0231 0.0601 0.06
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0045 0.0109
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0049 0.0084 0.0159
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0344 0.0921 0.0934
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0008 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0049 0.0084 0.0159
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0054 0.0099 0.0098
Trichomonas vaginalis glucosylceramidase, putative 0.0505 0.1379 0.3456
Leishmania major cytochrome p450-like protein 0.0101 0.0232 0.0245
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0085
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0231 0.0601 0.1134
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.007 0.0142 0.0141
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0058 0.011 0.011
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0161 0.0401 0.0757
Echinococcus granulosus tyrosine protein kinase Fyn 0.0046 0.0077 0.0076
Loa Loa (eye worm) hypothetical protein 0.0058 0.011 0.0207
Brugia malayi hypothetical protein 0.0231 0.0601 0.1032
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0032 0.0031
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0128 0.0308 0.1157
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0075 0.0157 0.0589

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.001 uM Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarization ChEMBL. 18242992
IC50 (binding) = 0.001 uM Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarization ChEMBL. 18242992

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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