Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0137 | 0.5074 | 0.865 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0018 | 0 | 0.5 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0137 | 0.5074 | 1 |
Onchocerca volvulus | 0.0018 | 0 | 0.5 | |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0137 | 0.5074 | 0.865 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0155 | 0.5866 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0252 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0018 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0155 | 0.5866 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0155 | 0.5866 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0018 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.