Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | tumor protein p63 | 0.0337 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0067 | 0.0592 | 0.0592 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0082 | 0.1124 | 0.5755 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.2077 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0082 | 0.1124 | 0.5412 |
Brugia malayi | Common central domain of tyrosinase family protein | 0.0106 | 0.1953 | 0.9404 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1124 | 0.5755 |
Brugia malayi | ShTK domain containing protein | 0.0106 | 0.1953 | 0.9404 |
Loa Loa (eye worm) | carboxylesterase | 0.0067 | 0.0592 | 0.3031 |
Schistosoma mansoni | tyrosinase precursor | 0.0106 | 0.1953 | 0.471 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1124 | 0.5755 |
Onchocerca volvulus | 0.0106 | 0.1953 | 1 | |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0106 | 0.1953 | 0.9404 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0592 | 0.3031 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.011 | 0.2077 | 0.2077 |
Brugia malayi | Blistered cuticle protein 3 | 0.0082 | 0.1124 | 0.5412 |
Echinococcus granulosus | peroxidasin | 0.0082 | 0.1124 | 0.1124 |
Brugia malayi | Animal haem peroxidase family protein | 0.0082 | 0.1124 | 0.5412 |
Schistosoma mansoni | thyroid hormone receptor | 0.0164 | 0.3983 | 0.9604 |
Brugia malayi | Hypothetical tyrosinase-like protein F21C3.2 in chromosome I | 0.0106 | 0.1953 | 0.9404 |
Echinococcus multilocularis | peroxidasin | 0.0082 | 0.1124 | 0.1124 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0126 | 0.2634 | 0.2634 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.4147 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1124 | 0.5755 |
Loa Loa (eye worm) | tyrosinase 1 | 0.0106 | 0.1953 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0067 | 0.0592 | 0.285 |
Echinococcus multilocularis | acetylcholinesterase | 0.0067 | 0.0592 | 0.0592 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0082 | 0.1124 | 0.5755 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1124 | 0.5755 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1124 | 0.5755 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1124 | 0.5755 |
Onchocerca volvulus | 0.0106 | 0.1953 | 1 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0082 | 0.1124 | 0.5412 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0106 | 0.1953 | 0.9404 |
Brugia malayi | Animal haem peroxidase family protein | 0.0082 | 0.1124 | 0.5412 |
Brugia malayi | hypothetical protein | 0.0082 | 0.1124 | 0.5412 |
Schistosoma mansoni | peroxidasin | 0.0082 | 0.1124 | 0.2711 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1124 | 0.5755 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1124 | 0.5755 |
Echinococcus granulosus | acetylcholinesterase | 0.0067 | 0.0592 | 0.0592 |
Echinococcus multilocularis | geminin | 0.0169 | 0.4147 | 0.4147 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0126 | 0.2634 | 0.2634 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.011 | 0.2077 | 0.2077 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0067 | 0.0592 | 0.1428 |
Schistosoma mansoni | lipoxygenase | 0.0086 | 0.1254 | 0.3025 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0123 | 0.2544 | 0.2544 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.011 | 0.2077 | 0.5009 |
Brugia malayi | Animal haem peroxidase family protein | 0.0082 | 0.1124 | 0.5412 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1124 | 0.5755 |
Echinococcus granulosus | carboxylesterase 5A | 0.0067 | 0.0592 | 0.0592 |
Brugia malayi | Peroxidasin | 0.0082 | 0.1124 | 0.5412 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0592 | 0.3031 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0082 | 0.1124 | 0.5755 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0106 | 0.1953 | 0.9404 |
Schistosoma mansoni | tyrosinase precursor | 0.0106 | 0.1953 | 0.471 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.2077 | 0.5009 |
Echinococcus granulosus | geminin | 0.0169 | 0.4147 | 0.4147 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0123 | 0.2544 | 0.2544 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0106 | 0.1953 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0082 | 0.1124 | 0.5755 |
Onchocerca volvulus | 0.0106 | 0.1953 | 1 | |
Echinococcus granulosus | acetylcholinesterase | 0.0067 | 0.0592 | 0.0592 |
Onchocerca volvulus | 0.0106 | 0.1953 | 1 | |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.2077 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0067 | 0.0592 | 0.3031 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.1953 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1124 | 0.5755 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0082 | 0.1124 | 0.5755 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.2077 | 0.5 |
Schistosoma mansoni | lipoxygenase | 0.0123 | 0.2544 | 0.6133 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.4147 | 1 |
Schistosoma mansoni | peroxidasin | 0.0082 | 0.1124 | 0.2711 |
Brugia malayi | Carboxylesterase family protein | 0.0067 | 0.0592 | 0.285 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1124 | 0.5755 |
Schistosoma mansoni | thyroid hormone receptor | 0.0164 | 0.3983 | 0.9604 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1124 | 0.5755 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1124 | 0.5755 |
Brugia malayi | hypothetical protein | 0.011 | 0.2077 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1124 | 0.5755 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.1953 | 1 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.2077 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0067 | 0.0592 | 0.0592 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0164 | 0.3983 | 0.3983 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0106 | 0.1953 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0126 | 0.2634 | 0.635 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.