Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0139 | 0.2166 | 0.827 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.2155 | 0.2155 |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0063 | 0.0825 | 0.1297 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0019 | 0.006 | 0.0095 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0107 | 0.1605 | 0.1605 |
Schistosoma mansoni | regulator of G protein signaling | 0.0019 | 0.006 | 0.0104 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0042 | 0.045 | 0.2757 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0107 | 0.1605 | 0.1605 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0107 | 0.1605 | 0.2522 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0047 | 0.0541 | 0.0935 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0019 | 0.006 | 0.0095 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.045 | 0.0327 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0019 | 0.006 | 0.0104 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0107 | 0.1605 | 0.2522 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0199 | 0.0199 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0107 | 0.1605 | 0.2522 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0107 | 0.1605 | 0.1605 |
Loa Loa (eye worm) | abnormal epIthelia family member | 0.0024 | 0.0147 | 0.0147 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.01 | 0.1472 | 0.2313 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0037 | 0.0377 | 0.0593 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0107 | 0.1605 | 0.2522 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0037 | 0.0377 | 0.2243 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.006 | 0.0783 | 0.0783 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0019 | 0.006 | 0.006 |
Schistosoma mansoni | regulator of G protein signaling | 0.0019 | 0.006 | 0.0104 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.045 | 0.1685 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.01 | 0.1474 | 0.1474 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0461 | 0.0461 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.006 | 0.0783 | 0.0783 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0107 | 0.1605 | 0.277 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0208 | 0.0208 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0345 | 0.5793 | 0.9104 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0067 | 0.0894 | 0.5908 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.0894 | 0.2324 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.036 | 0.0565 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0607 | 0.0607 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0037 | 0.0377 | 0.113 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.006 | 0.006 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0533 | 0.0838 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0533 | 0.0533 |
Brugia malayi | ecdysteroid receptor | 0.0262 | 0.4334 | 0.4334 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0139 | 0.2166 | 0.827 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1605 | 0.1605 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0107 | 0.1605 | 0.1605 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0107 | 0.1605 | 0.277 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0139 | 0.2166 | 0.827 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0147 | 0.0147 |
Schistosoma mansoni | cell polarity protein | 0.0024 | 0.0147 | 0.0254 |
Schistosoma mansoni | zinc finger protein | 0.0047 | 0.0541 | 0.0935 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0047 | 0.0541 | 0.0541 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0019 | 0.006 | 0.0095 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0139 | 0.2166 | 0.827 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0107 | 0.1605 | 0.1605 |
Brugia malayi | hypothetical protein | 0.0036 | 0.036 | 0.036 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0019 | 0.006 | 0.0095 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.045 | 0.1685 |
Echinococcus granulosus | dna polymerase kappa | 0.0042 | 0.045 | 0.0707 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0164 | 0.2601 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.045 | 0.1685 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0107 | 0.1605 | 0.2522 |
Brugia malayi | nuclear receptor NHR-88 | 0.0107 | 0.1605 | 0.1605 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0234 | 0.3842 | 0.3842 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.064 | 0.064 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0019 | 0.006 | 0.0104 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.01 | 0.1474 | 0.2316 |
Brugia malayi | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0067 | 0.0894 | 0.3191 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0019 | 0.006 | 0.006 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0533 | 0.0838 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.036 | 0.212 |
Loa Loa (eye worm) | DR-78 | 0.0047 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.006 | 0.006 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0047 | 0.0541 | 0.0851 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0039 | 0.0399 | 0.0628 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0326 | 0.0562 |
Treponema pallidum | DNA gyrase, subunit B (gyrB) | 0.0021 | 0.0083 | 0.5 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0199 | 0.0344 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0164 | 0.2601 | 1 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0019 | 0.006 | 0.0095 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0047 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0147 | 0.0147 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.2735 | 0.4722 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0444 | 0.0767 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0199 | 0.0199 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0107 | 0.1605 | 0.277 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0139 | 0.2166 | 0.827 |
Schistosoma mansoni | axis inhibition protein axin | 0.0019 | 0.006 | 0.0104 |
Schistosoma mansoni | thyroid hormone receptor | 0.0107 | 0.1605 | 0.277 |
Brugia malayi | Thrombospondin N-terminal -like domain containing protein | 0.0024 | 0.0147 | 0.0147 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.006 | 0.0783 | 0.0783 |
Schistosoma mansoni | patched 1 | 0.01 | 0.1474 | 0.2544 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0607 | 0.0607 |
Echinococcus multilocularis | expressed protein | 0.0378 | 0.6363 | 1 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.0138 | 0.2155 | 0.3386 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0107 | 0.1605 | 0.1605 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0049 | 0.0589 | 0.0952 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0024 | 0.0147 | 0.0231 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0019 | 0.006 | 0.0095 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0024 | 0.0147 | 0.0254 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0019 | 0.006 | 0.006 |
Brugia malayi | PXA domain containing protein | 0.0019 | 0.006 | 0.006 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0107 | 0.1605 | 0.2522 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0037 | 0.0377 | 0.0593 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0047 | 0.0541 | 0.0851 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0199 | 0.0313 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0024 | 0.0147 | 0.0231 |
Mycobacterium leprae | putative cytochrome p450 | 0.0139 | 0.2166 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0139 | 0.2166 | 0.827 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0047 | 0.0541 | 0.0541 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0107 | 0.1605 | 0.2522 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0019 | 0.006 | 0.006 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.036 | 0.212 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0107 | 0.1605 | 0.1605 |
Brugia malayi | hypothetical protein | 0.0019 | 0.006 | 0.006 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0037 | 0.0377 | 0.2243 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0533 | 0.0921 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0047 | 0.0541 | 0.0851 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0037 | 0.0377 | 0.0593 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0067 | 0.0894 | 0.0894 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.006 | 0.0783 | 0.1351 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0139 | 0.2166 | 0.827 |
Echinococcus multilocularis | protein patched | 0.01 | 0.1474 | 0.2316 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0107 | 0.1605 | 0.1605 |
Brugia malayi | laminin alpha chain | 0.0024 | 0.0147 | 0.0147 |
Schistosoma mansoni | nuclear receptor | 0.0047 | 0.0541 | 0.0935 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0019 | 0.006 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.0138 | 0.2155 | 0.8227 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0037 | 0.0377 | 0.3689 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0199 | 0.0199 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase, topoisomerase II, B subunit, GyrB | 0.0021 | 0.0083 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Leishmania major | DNA topoisomerase ii | 0.0057 | 0.0714 | 0.2472 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0107 | 0.1605 | 0.3399 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1474 | 0.1474 |
Echinococcus multilocularis | dna polymerase kappa | 0.0042 | 0.045 | 0.0707 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0326 | 0.0326 |
Schistosoma mansoni | lamin | 0.0027 | 0.0199 | 0.0344 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0034 | 0.032 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0107 | 0.1605 | 0.277 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0377 | 0.0377 |
Schistosoma mansoni | coup transcription factor | 0.0107 | 0.1605 | 0.277 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0107 | 0.1605 | 0.277 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0047 | 0.0541 | 0.0851 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.045 | 0.1685 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0107 | 0.1605 | 0.1605 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0138 | 0.2155 | 0.8219 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0019 | 0.006 | 0.0095 |
Schistosoma mansoni | lamin | 0.0027 | 0.0199 | 0.0344 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0067 | 0.0894 | 0.1544 |
Brugia malayi | nuclear hormone receptor | 0.0047 | 0.0541 | 0.0541 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0042 | 0.045 | 0.1457 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0107 | 0.1605 | 0.277 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.006 | 0.006 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0139 | 0.2166 | 0.827 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.045 | 0.0327 |
Echinococcus granulosus | geminin | 0.0171 | 0.2735 | 0.4299 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.0063 | 0.0825 | 0.0825 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.045 | 0.0327 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0138 | 0.2155 | 0.7992 |
Schistosoma mansoni | nuclear hormone receptor | 0.0047 | 0.0541 | 0.0935 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0107 | 0.1605 | 0.1605 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.01 | 0.1472 | 0.1472 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0345 | 0.5793 | 0.9104 |
Echinococcus multilocularis | geminin | 0.0171 | 0.2735 | 0.4299 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.0894 | 0.2324 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0057 | 0.0714 | 0.1514 |
Brugia malayi | follicle stimulating hormone receptor | 0.0234 | 0.3842 | 0.3842 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0139 | 0.2166 | 0.827 |
Trypanosoma brucei | DNA topoisomerase ii | 0.0049 | 0.0589 | 0.2222 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0444 | 0.0767 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0199 | 0.0313 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.006 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0019 | 0.006 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0783 | 0.0783 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.019 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0783 | 0.0783 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0139 | 0.2166 | 0.827 |
Onchocerca volvulus | 0.0047 | 0.0541 | 0.0828 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0273 | 0.0998 |
Plasmodium vivax | DNA topoisomerase II, putative | 0.0063 | 0.0825 | 1 |
Brugia malayi | tailless protein | 0.0047 | 0.0541 | 0.0541 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0046 | 0.0521 | 0.0779 |
Echinococcus granulosus | expressed conserved protein | 0.0094 | 0.1365 | 0.2146 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0199 | 0.0199 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0039 | 0.0399 | 0.0628 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0199 | 0.0313 |
Brugia malayi | nuclear receptor NHR-88 | 0.0047 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0107 | 0.1605 | 0.1605 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0019 | 0.006 | 0.0095 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0047 | 0.0541 | 0.0828 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.0138 | 0.2155 | 0.2155 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0164 | 0.2601 | 1 |
Trypanosoma brucei | DNA topoisomerase II alpha, putative | 0.0057 | 0.0714 | 0.2705 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0019 | 0.006 | 0.0104 |
Brugia malayi | ecdysone receptor | 0.0047 | 0.0541 | 0.0541 |
Brugia malayi | nuclear hormone receptor | 0.0107 | 0.1605 | 0.1605 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.036 | 0.212 |
Echinococcus granulosus | lamin | 0.0027 | 0.0199 | 0.0313 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0067 | 0.0894 | 0.1405 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0019 | 0.006 | 0.006 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.036 | 0.0621 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0107 | 0.1605 | 0.1605 |
Schistosoma mansoni | thyroid hormone receptor | 0.0107 | 0.1605 | 0.277 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.064 | 0.1104 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0019 | 0.006 | 0.0104 |
Brugia malayi | conserved hypotetical protein | 0.0047 | 0.0541 | 0.0541 |
Trichomonas vaginalis | conserved hypothetical protein | 0.01 | 0.1474 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0047 | 0.0541 | 0.0541 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0139 | 0.2166 | 0.827 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0147 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1605 | 0.1605 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0461 | 0.0461 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0139 | 0.2166 | 0.827 |
Schistosoma mansoni | axis inhibition protein axin | 0.0019 | 0.006 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.045 | 0.1685 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0065 | 0.0862 | 0.567 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0094 | 0.0309 |
Brugia malayi | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0037 | 0.0377 | 0.1404 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0138 | 0.2155 | 0.7992 |
Trichomonas vaginalis | DNA topoisomerase II, putative | 0.0063 | 0.0825 | 0.5412 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0063 | 0.0825 | 0.0825 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 0.0094 | 0.0044 |
Brugia malayi | CHE-14 protein | 0.01 | 0.1474 | 0.1474 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0107 | 0.1605 | 0.2522 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0047 | 0.0541 | 0.0935 |
Schistosoma mansoni | chondroitin sulfate proteoglycan-related | 0.0024 | 0.0147 | 0.0254 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.036 | 0.212 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0019 | 0.006 | 0.006 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0107 | 0.1605 | 0.1605 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0139 | 0.2166 | 0.827 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0019 | 0.006 | 0.0095 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.045 | 0.1685 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0037 | 0.0377 | 0.0377 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0139 | 0.2166 | 0.827 |
Schistosoma mansoni | regulator of G protein signaling | 0.0019 | 0.006 | 0.0104 |
Brugia malayi | PXA domain containing protein | 0.0019 | 0.006 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0345 | 0.5793 | 0.5793 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0047 | 0.0541 | 0.0851 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0107 | 0.1605 | 0.2522 |
Echinococcus multilocularis | pikachurin | 0.0024 | 0.0147 | 0.0231 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0037 | 0.0377 | 0.0652 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0047 | 0.0541 | 0.0935 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1605 | 0.1605 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1605 | 0.1605 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0047 | 0.0541 | 0.0851 |
Schistosoma mansoni | slit | 0.0024 | 0.0147 | 0.0254 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0139 | 0.2166 | 0.827 |
Mycobacterium ulcerans | oxidoreductase | 0.0125 | 0.1916 | 0.7277 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.0138 | 0.2155 | 0.3386 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0019 | 0.006 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0019 | 0.006 | 0.006 |
Brugia malayi | nuclear receptor RXR | 0.006 | 0.0783 | 0.0783 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0107 | 0.1605 | 0.1605 |
Loa Loa (eye worm) | hypothetical protein | 0.0262 | 0.4334 | 0.4334 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0107 | 0.1605 | 0.1605 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0326 | 0.0326 |
Brugia malayi | nuclear receptor RXR | 0.0047 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.006 | 0.006 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0067 | 0.0894 | 0.0894 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0047 | 0.0541 | 0.0828 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0139 | 0.2166 | 0.827 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0199 | 0.0313 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0208 | 0.0208 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0047 | 0.0541 | 0.0851 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0139 | 0.2166 | 0.827 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0107 | 0.1605 | 0.1605 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0049 | 0.0589 | 0.0952 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0273 | 0.0998 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0063 | 0.0825 | 0.5421 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0158 | 0.2501 | 0.4318 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0533 | 0.0838 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0199 | 0.0199 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0019 | 0.006 | 0.0095 |
Schistosoma mansoni | DNA topoisomerase II | 0.0063 | 0.0825 | 0.1425 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Schistosoma mansoni | nuclear hormone receptor | 0.0107 | 0.1605 | 0.277 |
Brugia malayi | hypothetical protein | 0.0019 | 0.006 | 0.006 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0533 | 0.0921 |
Brugia malayi | EGF-like domain containing protein | 0.0024 | 0.0147 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1472 | 0.1472 |
Schistosoma mansoni | nuclear receptor | 0.0047 | 0.0541 | 0.0935 |
Brugia malayi | laminin-like protein K08C7.3 precursor | 0.0024 | 0.0147 | 0.0147 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0199 | 0.3226 | 0.507 |
Echinococcus granulosus | FTZ F1 alpha | 0.0107 | 0.1605 | 0.2522 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.006 | 0.0783 | 0.1351 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.01 | 0.1472 | 0.2313 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0035 | 0.0333 | 0.1231 |
Leishmania major | mitochondrial DNA topoisomerase II | 0.0049 | 0.0589 | 0.1974 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0139 | 0.2166 | 0.827 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.01 | 0.1472 | 1 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0065 | 0.0862 | 0.567 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0042 | 0.045 | 0.1685 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0046 | 0.0521 | 0.0779 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.0138 | 0.2155 | 0.372 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0164 | 0.2601 | 1 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0345 | 0.5793 | 0.5793 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0019 | 0.006 | 0.0104 |
Echinococcus granulosus | axis inhibition protein axin | 0.0019 | 0.006 | 0.0095 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.036 | 0.0621 |
Brugia malayi | nuclear receptor NHR-67 | 0.0047 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0607 | 0.0607 |
Loa Loa (eye worm) | hypothetical protein | 0.0584 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0047 | 0.0541 | 0.0935 |
Onchocerca volvulus | 0.0107 | 0.1605 | 0.3399 | |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.006 | 0.006 |
Echinococcus multilocularis | slit 2 protein | 0.0024 | 0.0147 | 0.0231 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.2735 | 0.4722 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0047 | 0.0541 | 0.0541 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0037 | 0.0377 | 0.2246 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0107 | 0.1605 | 0.1605 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0037 | 0.0377 | 0.0593 |
Brugia malayi | hypothetical protein | 0.006 | 0.0783 | 0.0783 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0107 | 0.1605 | 0.2522 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0042 | 0.045 | 0.2757 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.01 | 0.1474 | 0.2316 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.045 | 0.1685 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0047 | 0.0541 | 0.0541 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0047 | 0.0541 | 0.0851 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0047 | 0.0541 | 0.0541 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0042 | 0.045 | 0.1685 |
Brugia malayi | polk-prov protein | 0.0031 | 0.0273 | 0.0273 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0107 | 0.1605 | 0.2522 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0107 | 0.1605 | 0.2522 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0107 | 0.1605 | 0.1605 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0139 | 0.2166 | 0.827 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0019 | 0.006 | 0.0095 |
Echinococcus granulosus | axis inhibition protein axin | 0.0019 | 0.006 | 0.0095 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.0019 | 0.006 | 0.006 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.045 | 0.1685 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0164 | 0.2601 | 1 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0057 | 0.0714 | 0.1514 |
Echinococcus multilocularis | protein dispatched 1 | 0.0106 | 0.158 | 0.2483 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.045 | 0.1685 |
Echinococcus granulosus | pikachurin | 0.0024 | 0.0147 | 0.0231 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0125 | 0.1916 | 0.7277 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0019 | 0.006 | 0.006 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0107 | 0.1605 | 0.1605 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0107 | 0.1605 | 0.1605 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0047 | 0.0541 | 0.0541 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0063 | 0.0825 | 0.1297 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0444 | 0.0767 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0107 | 0.1605 | 0.3399 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0139 | 0.2166 | 0.827 |
Plasmodium falciparum | DNA topoisomerase 2 | 0.0063 | 0.0825 | 1 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0037 | 0.0377 | 0.0652 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0047 | 0.0541 | 0.0851 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0533 | 0.0838 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0783 | 0.0783 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0139 | 0.2166 | 0.827 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0783 | 0.0783 |
Schistosoma mansoni | regulator of G protein signaling | 0.0019 | 0.006 | 0.0104 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0047 | 0.0541 | 0.0851 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0019 | 0.006 | 0.0095 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0107 | 0.1605 | 0.277 |
Brugia malayi | Probable DNA topoisomerase II | 0.0063 | 0.0825 | 0.0825 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0107 | 0.1605 | 0.1605 |
Toxoplasma gondii | DNA topoisomerase 2, putative | 0.0063 | 0.0825 | 1 |
Echinococcus granulosus | slit 2 protein | 0.0024 | 0.0147 | 0.0231 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.036 | 0.0565 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0063 | 0.0825 | 0.0825 |
Brugia malayi | steroid hormone receptor | 0.0107 | 0.1605 | 0.1605 |
Echinococcus granulosus | expressed protein | 0.0378 | 0.6363 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.006 | 0.0783 | 0.123 |
Giardia lamblia | DNA topoisomerase II | 0.006 | 0.0777 | 0.8889 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0065 | 0.0862 | 0.567 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0042 | 0.045 | 0.1457 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0019 | 0.006 | 0.0095 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.006 | 0.0783 | 0.123 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.0046 | 0.0521 | 0.0779 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0107 | 0.1605 | 0.2522 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0138 | 0.2155 | 0.8274 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0107 | 0.1605 | 0.277 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0533 | 0.0533 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0107 | 0.1605 | 0.2522 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0273 | 0.0273 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0444 | 0.0767 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0139 | 0.2166 | 0.827 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1605 | 0.1605 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0107 | 0.1605 | 0.1605 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0139 | 0.2166 | 0.827 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0139 | 0.2166 | 0.827 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0107 | 0.1605 | 0.2522 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0107 | 0.1605 | 0.2522 |
Onchocerca volvulus | 0.0047 | 0.0541 | 0.0828 | |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0047 | 0.0541 | 0.0541 |
Schistosoma mansoni | regulator of G protein signaling | 0.0019 | 0.006 | 0.0104 |
Trypanosoma brucei | unspecified product | 0.0035 | 0.0333 | 0.1231 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1605 | 0.1605 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0533 | 0.0921 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0199 | 0.0313 |
Echinococcus multilocularis | expressed conserved protein | 0.0094 | 0.1365 | 0.2146 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0065 | 0.0862 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0047 | 0.0541 | 0.0851 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0107 | 0.1605 | 0.277 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1605 | 0.1605 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0107 | 0.1605 | 0.2522 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0037 | 0.0377 | 0.0593 |
Loa Loa (eye worm) | RGS-3 protein | 0.0019 | 0.006 | 0.006 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.045 | 0.0327 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.0019 | 0.006 | 0.006 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0037 | 0.0377 | 0.2243 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0199 | 0.3226 | 0.507 |
Brugia malayi | hypothetical protein | 0.006 | 0.0783 | 0.0783 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0019 | 0.006 | 0.0095 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0037 | 0.0377 | 0.0593 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0345 | 0.5793 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0107 | 0.1605 | 0.1605 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0783 | 0.0783 |
Echinococcus granulosus | Protein patched homolog 1 | 0.01 | 0.1474 | 0.2316 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0139 | 0.2166 | 0.827 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0607 | 0.0607 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0067 | 0.0894 | 0.1405 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0047 | 0.0541 | 0.0851 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0164 | 0.2601 | 1 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0019 | 0.006 | 0.0104 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0019 | 0.006 | 0.0095 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.0894 | 0.3401 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0107 | 0.1605 | 0.1605 |
Trypanosoma brucei | DNA topoisomerase II beta, putative | 0.0057 | 0.0714 | 0.2705 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0139 | 0.2166 | 0.827 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0262 | 0.4334 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Inhibition of human recombinant PI3Kalpha assessed as formation of PI3P from PI by cell free kinase assay | ChEMBL. | 18501601 | |
Activity (binding) | Inhibition of HIF1alpha (unknown origin) | ChEMBL. | 18501601 | |
Activity (binding) | Inhibition of hypoxia-induced HIF1 activation in human U251HRE cells by cell based reporter gene assay | ChEMBL. | 18501601 | |
Activity (binding) | 0 | Inhibition of PI3K in human H460 cells assessed as Akt phosphorylation at Ser 473 upto 30 uM | ChEMBL. | 18501601 |
Activity (binding) | 0 | Inhibition of mTOR in human H460 cells assessed as p70S6 phosphorylation at Thr 389 upto 30 uM | ChEMBL. | 18501601 |
Activity (binding) | 0 | Inhibition of HIF1alpha (unknown origin) | ChEMBL. | 18501601 |
Activity (binding) | 0 | Inhibition of human recombinant PI3Kalpha assessed as formation of PI3P from PI by cell free kinase assay | ChEMBL. | 18501601 |
Activity (binding) | 0 | Inhibition of hypoxia-induced HIF1 activation in human U251HRE cells by cell based reporter gene assay | ChEMBL. | 18501601 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.