Detailed information for compound 511242

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 2309.56 | Formula: C95H161N33O32S
  • H donors: 35 H acceptors: 33 LogP: -10.87 Rotable bonds: 102
    Rule of 5 violations (Lipinski): 4
  • SMILES: CSCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCCNC(=N)N)CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](CC)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](CC)C)NC(=O)[C@H]([C@H](CC)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)N)CC(=O)O)CCCNC(=N)N)CC(=O)N)C)CCCNC(=N)N)Cc1[nH]cnc1)CC(C)C)C)CCC(=O)N)CO
  • InChi: 1S/C95H161N33O32S/c1-14-44(8)71(126-85(152)58(34-64(98)131)122-78(145)52(21-18-29-107-94(101)102)117-90(157)72(45(9)15-2)128-91(158)73(46(10)16-3)127-86(153)61(37-69(139)140)119-76(143)50(96)23-26-66(133)134)89(156)112-48(12)75(142)114-51(20-17-28-106-93(99)100)77(144)121-57(33-49-38-105-41-110-49)82(149)120-56(32-42(4)5)81(148)111-47(11)74(141)115-53(24-25-63(97)130)80(147)125-70(43(6)7)88(155)109-39-65(132)113-59(35-67(135)136)83(150)124-62(40-129)87(154)116-54(27-31-161-13)79(146)123-60(36-68(137)138)84(151)118-55(92(159)160)22-19-30-108-95(103)104/h38,41-48,50-62,70-73,129H,14-37,39-40,96H2,1-13H3,(H2,97,130)(H2,98,131)(H,105,110)(H,109,155)(H,111,148)(H,112,156)(H,113,132)(H,114,142)(H,115,141)(H,116,154)(H,117,157)(H,118,151)(H,119,143)(H,120,149)(H,121,144)(H,122,145)(H,123,146)(H,124,150)(H,125,147)(H,126,152)(H,127,153)(H,128,158)(H,133,134)(H,135,136)(H,137,138)(H,139,140)(H,159,160)(H4,99,100,106)(H4,101,102,107)(H4,103,104,108)/t44-,45-,46-,47-,48-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,70-,71-,72-,73-/m0/s1
  • InChiKey: GQSZOADIYRCRRU-ICVVQHRASA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0256 1
Giardia lamblia Multidrug resistance-associated protein Mrp2 0.0011 0.0033 0.1271
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0129 0.0246
Schistosoma mansoni hypothetical protein 0.0167 0.2003 0.451
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0014 0.0032
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0232 0.0523
Echinococcus granulosus ATP binding cassette sub family B 0.0012 0.0038 0.0083
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0099 0.0568
Schistosoma mansoni follistatin 0.0019 0.0124 0.0279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0099 0.0568
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0027
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0129 0.0129
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0129 0.0284
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0156 0.0352
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0339 0.1108
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0339 0.1108
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0099 0.0568
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0099 0.0099
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0156 0.1039
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0029 0.0254 0.1845
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0029 0.0254 0.0254
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0014 0.0014
Mycobacterium leprae Probable lipase LipE 0.0036 0.0339 0.2495
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0014 0.0032
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0124 0.365
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0012 0.0038 0.0045
Entamoeba histolytica P-glyco protein 6, putative 0.0029 0.0254 0.1845
Loa Loa (eye worm) hypothetical protein 0.0036 0.0339 0.0646
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0099 0.0568
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0339 0.2529
Entamoeba histolytica P-glycoprotein-1 0.0029 0.0254 0.1845
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0099 0.0223
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0014 0.0032
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0027 0.0232 0.0442
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0129 0.0284
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0027 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0029 0.0254 0.0484
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0025 0.02 0.5888
Echinococcus granulosus multidrug resistance protein 1 0.0018 0.0112 0.0246
Loa Loa (eye worm) multidrug resistance protein 3 0.0029 0.0254 0.0484
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0129 0.0817
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0029 0.0254 0.1845
Brugia malayi ABC transporter family protein 0.0012 0.0038 0.0085
Schistosoma mansoni sodium-bile acid cotransporter related 0.0242 0.2947 0.6636
Loa Loa (eye worm) hypothetical protein 0.0013 0.0052 0.01
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0129 0.0291
Giardia lamblia MRP-like ABC transporter 0.0025 0.02 0.779
Onchocerca volvulus 0.0027 0.0232 0.0416
Onchocerca volvulus 0.0361 0.4441 0.845
Loa Loa (eye worm) hypothetical protein 0.0011 0.0033 0.0062
Loa Loa (eye worm) hypothetical protein 0.0027 0.0232 0.0442
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0029 0.0254 0.1845
Loa Loa (eye worm) hypothetical protein 0.0025 0.02 0.038
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0339 0.0764
Loa Loa (eye worm) ABC transporter 0.0012 0.0038 0.0072
Schistosoma mansoni multidrug resistance protein 0.0029 0.0254 0.0572
Echinococcus granulosus lamin dm0 0.0027 0.0226 0.0498
Entamoeba histolytica P-glycoprotein-2, putative 0.0029 0.0254 0.1845
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0124 0.0279
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0617 0.4816
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0129 0.0291
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0232 0.0523
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0014 0.0032
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1245 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0014 0.0032
Onchocerca volvulus 0.0029 0.0254 0.0458
Trichomonas vaginalis abcb9, putative 0.0029 0.0254 0.1845
Loa Loa (eye worm) fibroinase 0.0017 0.0099 0.0188
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0129 0.0284
Loa Loa (eye worm) hypothetical protein 0.0027 0.0232 0.0442
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.1245 1
Schistosoma mansoni multidrug resistance protein 0.0012 0.0038 0.0085
Brugia malayi hypothetical protein 0.0019 0.0129 0.0291
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0686 0.5385
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0129 0.0817
Brugia malayi Phospholipase A2 family protein 0.0089 0.1019 0.2295
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0129 0.0291
Mycobacterium ulcerans hypothetical protein 0.0036 0.0339 0.2495
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0686 0.5385
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0029 0.0254 0.1845
Schistosoma mansoni organic anion transporter 0.0027 0.0232 0.0523
Brugia malayi ABC transporter transmembrane region family protein 0.0012 0.0038 0.0085
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.007 0.1073
Brugia malayi multidrug resistance protein 3 0.0029 0.0254 0.0572
Loa Loa (eye worm) ABC transporter 0.0012 0.0038 0.0072
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0025 0.02 0.038
Leishmania major hypothetical protein, conserved 0.0036 0.0339 0.2529
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0099 0.386
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0099 0.0568
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0099 0.0568
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.1245 1
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0129 0.0817
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0025 0.02 0.138
Leishmania major p-glycoprotein e 0.0025 0.02 0.138
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0018 0.0112 0.0674
Schistosoma mansoni multidrug resistance protein 0.0011 0.0033 0.0073
Plasmodium falciparum ABC transporter B family member 4, putative 0.0012 0.0038 0.1472
Entamoeba histolytica P-glycoprotein-2, putative 0.0011 0.0033 0.0022
Loa Loa (eye worm) hypothetical protein 0.0036 0.0339 0.0646
Loa Loa (eye worm) ABC transporter 0.0012 0.0038 0.0072
Echinococcus granulosus intermediate filament protein 0.0027 0.0226 0.0498
Echinococcus multilocularis multidrug resistance protein 1 0.0029 0.0254 0.0254
Entamoeba histolytica ATP-binding cassette protein, putative 0.0025 0.02 0.1396
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0099 0.0568
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1245 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0124 0.0236
Schistosoma mansoni lamin 0.0027 0.0226 0.051
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0256 0.7559
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0099 0.0568
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0052 0.0115
Schistosoma mansoni intermediate filament proteins 0.0027 0.0226 0.051
Loa Loa (eye worm) ctsf protein 0.0017 0.0099 0.0188
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0012 0.0038 0.5
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0129 0.0284
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0129 0.0246
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0099 0.0568
Giardia lamblia Multidrug resistance-associated protein 1 0.0024 0.0195 0.7589
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0014 0.0032
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0129 0.0817
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0014 0.0032
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0038 0.1112
Echinococcus multilocularis ATP binding cassette sub family B 0.0028 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0027 0.0232 0.0442
Brugia malayi hypothetical protein 0.0027 0.0232 0.0523
Brugia malayi PXA domain containing protein 0.0019 0.0129 0.0291
Leishmania major cathepsin L-like protease 0.0017 0.0099 0.0549
Loa Loa (eye worm) hypothetical protein 0.0019 0.0129 0.0246
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0686 0.5385
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0339 0.0746
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.1245 0.2741
Onchocerca volvulus 0.0027 0.0226 0.0405
Schistosoma mansoni multidrug resistance protein 0.0029 0.0254 0.0572
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0099 0.0568
Loa Loa (eye worm) hypothetical protein 0.0036 0.0339 0.0646
Echinococcus granulosus FTZ F1 alpha 0.001 0.0014 0.0031
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0339 0.0646
Mycobacterium tuberculosis Conserved protein 0.0036 0.0339 0.1108
Echinococcus multilocularis cysteine protease 0.0017 0.0099 0.0099
Onchocerca volvulus Phospholipase A2 homolog 0.0425 0.5253 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0029 0.0254 0.0559
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0339 0.1108
Trypanosoma brucei multidrug resistance protein E 0.0025 0.02 0.138
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0129 0.0284
Brugia malayi hypothetical protein 0.0027 0.0232 0.0523
Loa Loa (eye worm) hypothetical protein 0.0011 0.003 0.0057
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0339 0.2543
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0129 0.0129
Mycobacterium ulcerans lipase LipD 0.0036 0.0339 0.2495
Onchocerca volvulus 0.0011 0.003 0.003
Leishmania major cathepsin L-like protease 0.0063 0.0686 0.5385
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0099 0.0549
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0014 0.0031
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0129 0.0129
Trypanosoma brucei p-glycoprotein 0.0025 0.02 0.138
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0052 0.0052
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0012 0.0038 0.0085
Entamoeba histolytica ATP-binding cassette protein, putative 0.0025 0.02 0.1396
Toxoplasma gondii cathepsin CPL 0.0017 0.0099 0.2918
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0012 0.0038 0.0085
Echinococcus multilocularis lamin dm0 0.0027 0.0226 0.0226
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0256 0.7559
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0029 0.0254 0.1845
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0339 0.2543
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0014 0.0032
Mycobacterium ulcerans beta-lactamase 0.0036 0.0339 0.2495
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0339 0.2495
Brugia malayi Cathepsin L-like precursor 0.0017 0.0099 0.0223
Entamoeba histolytica P-glycoprotein-2 0.0029 0.0254 0.1845
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0339 0.2495
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0029 0.0254 0.1845
Leishmania major cathepsin L-like protease 0.0017 0.0099 0.0549
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0099 0.0568
Echinococcus granulosus agrin 0.0019 0.0124 0.0272
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0256 0.1863
Trichomonas vaginalis esterase, putative 0.0036 0.0339 0.2543
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0014 0.0032
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0156 0.1039
Schistosoma mansoni organic anion transporter 0.0027 0.0232 0.0523
Loa Loa (eye worm) hypothetical protein 0.0027 0.0232 0.0442
Brugia malayi steroid hormone receptor 0.001 0.0014 0.0032
Loa Loa (eye worm) RecQ helicase 0.0021 0.0156 0.0297
Entamoeba histolytica ATP-binding cassette protein, putative 0.0025 0.02 0.1396
Plasmodium falciparum multidrug resistance-associated protein 1 0.0012 0.0038 0.1472
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0256 0.1863
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0099 0.0188
Echinococcus granulosus multidrug resistance protein 1 0.0029 0.0254 0.0559
Loa Loa (eye worm) hypothetical protein 0.0024 0.0195 0.037
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0129 0.0129
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0014 0.0032
Onchocerca volvulus 0.0017 0.0099 0.0162
Giardia lamblia ABC transporter, putative 0.0025 0.02 0.779
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.1245 0.2371
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0068 0.2004
Entamoeba histolytica hypothetical protein 0.0025 0.02 0.1396
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0038 0.0064
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0029 0.0254 0.1845
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0014 0.0032
Plasmodium vivax multidrug resistance protein 1, putative 0.0029 0.0254 0.7184
Giardia lamblia Multidrug resistance-associated protein 1 0.0025 0.02 0.779
Brugia malayi ABC transporter transmembrane region family protein 0.0025 0.02 0.045
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0339 0.2543
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0099 0.0162
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0686 0.5385
Trypanosoma cruzi MFS transporter, putative 0.0027 0.0232 0.1649
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0099 0.0099
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0012 0.0038 0.0045
Schistosoma mansoni hypothetical protein 0.0167 0.2003 0.451
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0686 0.5385
Loa Loa (eye worm) hypothetical protein 0.0029 0.0254 0.0484
Loa Loa (eye worm) hypothetical protein 0.0017 0.0102 0.0195
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0033 0.0022
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0256 1
Schistosoma mansoni multidrug resistance protein 0.0025 0.02 0.045
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0099 0.0099
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.1245 0.2804
Brugia malayi ABC transporter family protein 0.0012 0.0038 0.0085
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0038 0.1112
Giardia lamblia Hypothetical protein 0.0011 0.0033 0.1271
Brugia malayi ABC transporter transmembrane region family protein 0.0011 0.0033 0.0073
Brugia malayi P-glycoprotein-like protein 0.0012 0.0038 0.0085
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0129 0.0284
Loa Loa (eye worm) hypothetical protein 0.0017 0.0099 0.0188
Echinococcus multilocularis multidrug resistance associated protein 7 0.0025 0.02 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0099 0.0568
Schistosoma mansoni lamin 0.0027 0.0226 0.051
Brugia malayi ecdysteroid receptor 0.001 0.0014 0.0032
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1245 1
Loa Loa (eye worm) agrin synaptic family protein 0.0019 0.0124 0.0236
Onchocerca volvulus 0.0036 0.0339 0.062
Onchocerca volvulus 0.0036 0.0339 0.062
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0339 1
Entamoeba histolytica hypothetical protein 0.0019 0.0129 0.0817
Loa Loa (eye worm) beta-lactamase 0.0036 0.0339 0.0646
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0038 0.1112
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0099 0.0568
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0124 0.0279
Echinococcus granulosus ATP binding cassette sub family B 0.0012 0.0038 0.0083
Loa Loa (eye worm) hypothetical protein 0.0019 0.0129 0.0246
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0099 0.0568
Echinococcus granulosus sodium bile acid cotransporter 0.0361 0.4441 0.9773
Leishmania major pentamidine resistance protein 1 0.0025 0.02 0.138
Entamoeba histolytica P-glycoprotein 6, putative 0.0012 0.0038 0.0064
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0029 0.0254 0.0254
Echinococcus granulosus multidrug resistance protein 1 0.0029 0.0254 0.0559
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0256 0.7254
Trichomonas vaginalis ABC transporter, putative 0.0029 0.0254 0.1845
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0256 0.7559
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0256 0.1863
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.01 0.0226
Echinococcus multilocularis multidrug resistance protein 1 0.0018 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0027 0.0232 0.0442
Loa Loa (eye worm) hypothetical protein 0.0019 0.0129 0.0246
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0032 0.002
Leishmania major cathepsin L-like protease 0.0017 0.0099 0.0549
Trichomonas vaginalis taga, putative 0.0029 0.0254 0.1845
Brugia malayi ABC transporter 0.0012 0.0038 0.0085
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0099 0.0568
Echinococcus granulosus multidrug resistance associated protein 7 0.0025 0.02 0.0439
Leishmania major ABC-thiol transporter 0.0025 0.02 0.138
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0339 0.0339
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.1245 0.2371
Trypanosoma cruzi multidrug resistance protein E, putative 0.0025 0.02 0.138
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0029 0.0254 0.1845
Entamoeba histolytica P-glycoprotein 5, putative 0.0029 0.0254 0.1845
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0129 0.0246
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0014 0.0032
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0029 0.0254 0.7498
Brugia malayi nuclear hormone receptor 0.001 0.0014 0.0032
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0012 0.0038 0.0045
Trichomonas vaginalis abcb9, putative 0.0029 0.0254 0.1845
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0014 0.0014
Loa Loa (eye worm) phosphofructokinase 0.0107 0.1245 0.2371
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0014 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0014 0.0032
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0129 0.0284
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0033 0.0022
Loa Loa (eye worm) hypothetical protein 0.0036 0.0339 0.0646
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0129 0.0291
Echinococcus granulosus follistatin 0.0019 0.0124 0.0272
Brugia malayi Cathepsin L-like precursor 0.0011 0.003 0.0067
Brugia malayi Cathepsin L-like precursor 0.0017 0.0099 0.0223
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0029 0.0254 0.0559
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0027 0.0232 0.0232
Echinococcus granulosus cathepsin l1 0.0017 0.0099 0.0218
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0029 0.0254 0.1845
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0232 0.0416
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0686 0.5385
Toxoplasma gondii ABC1 family protein 0.0036 0.0339 1
Echinococcus multilocularis expressed protein 0.0369 0.4544 0.4544
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0029 0.0254 0.1845
Echinococcus granulosus expressed protein 0.0369 0.4544 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0129 0.0291
Entamoeba histolytica multidrug resistance protein, putative 0.0025 0.02 0.1396
Echinococcus multilocularis follistatin 0.0019 0.0124 0.0124
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0256 0.1863
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0226 0.0431
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0686 0.5385
Leishmania major cathepsin L-like protease 0.0017 0.0099 0.0549
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0226 0.0431
Echinococcus multilocularis geminin 0.0167 0.2003 0.2003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0226 0.0431
Brugia malayi Cathepsin L-like precursor 0.0017 0.0099 0.0223
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0028 0.0249 0.0548
Onchocerca volvulus 0.0017 0.0099 0.0162
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0099 0.0568
Plasmodium falciparum ABC transporter B family member 3, putative 0.0012 0.0038 0.1472
Onchocerca volvulus 0.0036 0.0339 0.062
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.1245 1
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0025 0.02 0.138
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0129 0.0129
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.1245 0.1245
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0129 0.0291
Echinococcus multilocularis musashi 0.0027 0.0226 0.0226
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0027
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0124 0.0279
Echinococcus multilocularis sodium bile acid cotransporter 0.0361 0.4441 0.4441
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0029 0.0254 0.7498
Schistosoma mansoni smdr1 0.0012 0.0038 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0014 0.0032
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0339 0.1108
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0025 0.02 0.138
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0099 0.0218
Loa Loa (eye worm) hypothetical protein 0.0036 0.0339 0.0646
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0038 0.1112
Leishmania major cathepsin L-like protease 0.0017 0.0099 0.0549
Schistosoma mansoni thyroid hormone receptor 0.001 0.0014 0.0032
Loa Loa (eye worm) hypothetical protein 0.0012 0.0046 0.0088
Loa Loa (eye worm) hypothetical protein 0.0019 0.0124 0.0236
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0339 0.2529
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0014 0.0014
Brugia malayi SPARC precursor 0.0019 0.0124 0.0279
Brugia malayi Cathepsin L-like precursor 0.0017 0.0099 0.0223
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0129 0.0129
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0129 0.0291
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0014 0.0032
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0686 0.5385
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1245 1
Schistosoma mansoni sodium-bile acid cotransporter 0.0118 0.1384 0.3117
Entamoeba histolytica ATP-binding cassette protein, putative 0.0025 0.02 0.1396
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0029 0.0254 0.1845
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0014 0.0014
Brugia malayi cathepsin L-like precursor 0.0011 0.003 0.0067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0014 0.0027
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0256 0.1863
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.003 0.0067
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0014 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0686 0.5385
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0014 0.0027
Mycobacterium tuberculosis Conserved protein 0.0036 0.0339 0.1108
Loa Loa (eye worm) hypothetical protein 0.0361 0.4441 0.8454
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0027
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0072
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0124 0.0236
Loa Loa (eye worm) hypothetical protein 0.0019 0.0124 0.0236
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0099 0.0568
Onchocerca volvulus 0.0027 0.0226 0.0405
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0686 0.5385
Trichomonas vaginalis ABC transporter, putative 0.0029 0.0254 0.1845
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0129 0.0291
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0232 0.0416
Brugia malayi ABC transporter family protein 0.0012 0.0038 0.0085
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0129 0.0129
Onchocerca volvulus 0.0027 0.0232 0.0416
Brugia malayi multidrug resistance related protein 1 0.0025 0.02 0.045
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0339 0.0764
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.007 0.0134
Echinococcus multilocularis multidrug resistance protein 1 0.0029 0.0254 0.0254
Echinococcus granulosus multidrug resistance protein 1 0.0029 0.0254 0.0559
Loa Loa (eye worm) hypothetical protein 0.0028 0.0249 0.0474
Entamoeba histolytica P-glycoprotein 6, putative 0.0012 0.0038 0.0064
Entamoeba histolytica P-glycoprotein-5 0.0029 0.0254 0.1845
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0029 0.0254 0.0559
Leishmania major p-glycoprotein 0.0029 0.0254 0.1829
Echinococcus granulosus multidrug resistance associated protein 1 0.0025 0.02 0.0439
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0256 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0014 0.0031
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0014 0.0014
Echinococcus multilocularis sodium bile acid cotransporter 0.0361 0.4441 0.4441
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0099 0.0568
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0014 0.0027
Onchocerca volvulus Putative organic anion transporter 0.0027 0.0232 0.0416
Plasmodium falciparum ABC transporter B family member 5, putative 0.0012 0.0038 0.1472
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0129 0.0291
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0339 0.2495
Brugia malayi hypothetical protein 0.0019 0.0129 0.0291
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0014 0.0027
Onchocerca volvulus Phospholipase A2 homolog 0.0089 0.1019 0.1918
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1245 1
Echinococcus multilocularis agrin 0.0019 0.0124 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0099 0.0568
Plasmodium falciparum ABC transporter B family member 7, putative 0.0012 0.0038 0.1472
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0014 0.0014
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0129 0.0291
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0129 0.0291
Echinococcus multilocularis multidrug resistance associated protein 4 0.0013 0.0052 0.0052
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0686 0.5385
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0129 0.0817
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0686 0.5385
Echinococcus multilocularis ATP binding cassette sub family B 0.0012 0.0038 0.0038
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0025 0.02 0.138
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.1245 1
Brugia malayi beta-lactamase family protein 0.0036 0.0339 0.0764
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0029 0.0254 0.1845
Brugia malayi hypothetical protein 0.0012 0.0038 0.0085
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0014 0.0014
Echinococcus multilocularis sodium bile acid cotransporter 0.0361 0.4441 0.4441
Entamoeba histolytica cysteine protease, putative 0.0017 0.0099 0.0568
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0014 0.0032
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0029 0.0254 0.1845
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.007 0.0158
Loa Loa (eye worm) hypothetical protein 0.0036 0.0339 0.0646
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0129 0.0284
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0014 0.0032
Echinococcus granulosus geminin 0.0167 0.2003 0.4408
Brugia malayi nuclear receptor NHR-88 0.001 0.0014 0.0032
Echinococcus granulosus multidrug resistance associated protein 4 0.0013 0.0052 0.0115
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0129 0.0129
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0124 0.365
Onchocerca volvulus 0.0017 0.0099 0.0162
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0099 0.0568
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.1245 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0099 0.0568
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0129 0.0246
Toxoplasma gondii ABC transporter family protein 0.0012 0.0038 0.1112
Plasmodium falciparum multidrug resistance-associated protein 2 0.0012 0.0038 0.1472
Brugia malayi phosphofructokinase 0.0107 0.1245 0.2804
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0129 0.0291
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0029 0.0254 0.1845
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0099 0.386
Brugia malayi Sodium Bile acid symporter family protein 0.0361 0.4441 1
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0011 0.0033 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0014 0.0032
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0025 0.02 0.138
Echinococcus granulosus sodium bile acid cotransporter 0.0361 0.4441 0.9773
Echinococcus granulosus cathepsin l1 0.0011 0.003 0.0066
Brugia malayi 6-phosphofructokinase 0.0108 0.125 0.2816
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0339 0.1108
Echinococcus multilocularis ATP binding cassette sub family B 0.0012 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0011 0.003 0.0057
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0014 0.0031
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0339 0.0764
Schistosoma mansoni agrin 0.0019 0.0124 0.0279
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0124 0.4834
Toxoplasma gondii protease inhibitor PI2 0.0019 0.0124 0.365
Schistosoma mansoni multidrug resistance protein 0.0025 0.02 0.045
Loa Loa (eye worm) hypothetical protein 0.0011 0.003 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0014 0.0032
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0029 0.0254 0.1845
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0014 0.0032
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0012 0.0038 0.0045
Onchocerca volvulus 0.0019 0.0124 0.0209
Mycobacterium tuberculosis Conserved protein 0.0036 0.0339 0.1108
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0029 0.0254 0.1845
Echinococcus granulosus sodium bile acid cotransporter 0.0361 0.4441 0.9773
Schistosoma mansoni thyroid hormone receptor 0.001 0.0014 0.0032
Brugia malayi Cathepsin L-like precursor 0.0017 0.0099 0.0223
Entamoeba histolytica P-glycoprotein-2 0.0029 0.0254 0.1845
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0029 0.0254 0.0484
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0099 0.0549
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0099 0.0188
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0256 0.1863
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0129 0.0246
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0038 0.1112
Toxoplasma gondii ABC transporter, putative 0.0012 0.0038 0.1112
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0129 0.0291
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0027
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0099 0.0162
Loa Loa (eye worm) hypothetical protein 0.0026 0.022 0.0419
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0099 0.0223
Schistosoma mansoni sodium-bile acid cotransporter related 0.0361 0.4441 1
Echinococcus granulosus bloom syndrome protein 0.0021 0.0156 0.0344
Leishmania major cathepsin L-like protease 0.0063 0.0686 0.5385
Echinococcus granulosus multidrug resistance protein 1 0.0018 0.0112 0.0246
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0686 0.5385
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0124 0.365
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0025 0.02 0.138
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0012 0.0038 0.0045
Schistosoma mansoni smdr2 0.0029 0.0254 0.0572
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0012 0.0038 0.0045
Echinococcus multilocularis expressed protein 0.0019 0.0124 0.0124
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.2758 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0124 0.0236
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1245 1
Toxoplasma gondii transporter, major facilitator family protein 0.0027 0.0232 0.6851
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.1245 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0339 0.2543
Onchocerca volvulus 0.0027 0.0232 0.0416
Schistosoma mansoni nuclear hormone receptor 0.001 0.0014 0.0032
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0156 0.0156
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0014 0.0014
Loa Loa (eye worm) cysteine protease 0.0017 0.0099 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0129 0.0817
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0029 0.0254 0.0559
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0027
Plasmodium vivax vivapain-2 0.0017 0.0099 0.2031
Loa Loa (eye worm) hypothetical protein 0.0027 0.0232 0.0442
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0099 0.0568
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0033 0.0022
Entamoeba histolytica P-glycoprotein 5, putative 0.0011 0.0033 0.0022
Leishmania major cathepsin L-like protease 0.0063 0.0686 0.5385
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0029 0.0254 0.0254
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0099 0.0568
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0339 0.2543
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0256 1
Brugia malayi prostaglandin transporter 0.0027 0.0232 0.0523
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0686 0.5385
Plasmodium falciparum multidrug resistance protein 2 0.0012 0.0038 0.1472
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0339 0.1108
Trichomonas vaginalis ABC transporter, putative 0.0029 0.0254 0.1845
Brugia malayi 6-phosphofructokinase 0.0107 0.1245 0.2804
Brugia malayi beta-lactamase family protein 0.0036 0.0339 0.0764
Onchocerca volvulus 0.0027 0.0232 0.0416
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0029 0.0254 0.0254
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0014 0.0014
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0029 0.0254 0.1845
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0099 0.0568
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0029 0.0254 0.1845
Entamoeba histolytica hypothetical protein 0.0019 0.0129 0.0817
Loa Loa (eye worm) hypothetical protein 0.0019 0.0129 0.0246
Plasmodium falciparum multidrug resistance protein 1 0.0029 0.0254 0.9919
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0027
Echinococcus multilocularis 0.0012 0.0038 0.0038
Echinococcus multilocularis lamin 0.0027 0.0226 0.0226
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0029 0.0254 0.1829
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0014 0.0027
Entamoeba histolytica hypothetical protein 0.0019 0.0129 0.0817
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0129 0.0284
Loa Loa (eye worm) hypothetical protein 0.0027 0.0232 0.0442
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0029 0.0254 0.1845
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0099 0.0099
Brugia malayi beta-lactamase 0.0036 0.0339 0.0764
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0686 0.5385
Brugia malayi secreted modular calcium-binding protein 1 0.0019 0.0124 0.0279
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0129 0.0291
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0029 0.0254 0.0254
Schistosoma mansoni multidrug resistance protein 0.0029 0.0254 0.0572
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0124 0.365
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0014 0.0032
Schistosoma mansoni multidrug resistance protein 0.0025 0.02 0.045
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0014 0.0031
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1245 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0012 0.0038 0.0038
Brugia malayi PXA domain containing protein 0.0019 0.0129 0.0291
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0129 0.0291
Trichomonas vaginalis ABC transporter, putative 0.0029 0.0254 0.1845
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0256 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0129 0.0246
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0029 0.0254 0.1845
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0014 0.0027
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0129 0.0291
Brugia malayi ABC transporter 0.0011 0.0033 0.0073
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0027 0.0232 0.0511
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0099 0.0218
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0099 0.386
Brugia malayi ABC transporter family protein 0.0029 0.0254 0.0572
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0014 0.0031
Loa Loa (eye worm) hypothetical protein 0.0425 0.5253 1
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0099 0.0223
Echinococcus multilocularis cysteine protease 0.0017 0.0099 0.0099
Giardia lamblia Multidrug resistance-associated protein 1 0.0025 0.02 0.779
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0029 0.0254 0.1845
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0129 0.0817
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.003 0.0067
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0226 0.051
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0014 0.0032
Loa Loa (eye worm) hypothetical protein 0.0089 0.1019 0.194
Echinococcus granulosus Solute carrier organic anion transporter family 0.0027 0.0232 0.0511
Schistosoma mansoni multidrug resistance protein 0.0025 0.02 0.045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0099 0.0568
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0099 0.0162
Brugia malayi Cathepsin L-like precursor 0.0017 0.0099 0.0223
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0012 0.0038 0.1112
Echinococcus granulosus ATP binding cassette sub family B 0.0011 0.0033 0.0072
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0025 0.02 0.138
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0014 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0339 0.2529
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0025 0.02 0.138
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0032 0.002
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0256 0.7254
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0014 0.0032
Echinococcus multilocularis ATP binding cassette sub family B 0.0012 0.0038 0.0038
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0129 0.0291
Loa Loa (eye worm) hypothetical protein 0.0019 0.0129 0.0246
Trypanosoma cruzi hypothetical protein 0.0013 0.0052 0.0163
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0012 0.0038 0.5
Echinococcus multilocularis multidrug resistance associated protein 1 0.0025 0.02 0.02
Onchocerca volvulus 0.0027 0.0232 0.0416
Echinococcus granulosus lamin 0.0027 0.0226 0.0498
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0014 0.0032
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0014 0.0027
Schistosoma mansoni coup transcription factor 0.001 0.0014 0.0032
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0129 0.0129
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.1245 0.2804
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0012 0.0038 0.0045
Plasmodium falciparum ABC transporter B family member 6, putative 0.0012 0.0038 0.1472
Brugia malayi Cathepsin L-like precursor 0.0011 0.003 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0099 0.0568
Loa Loa (eye worm) hypothetical protein 0.0025 0.02 0.038
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0129 0.0291
Onchocerca volvulus 0.0017 0.0099 0.0162
Brugia malayi intermediate filament protein 0.0027 0.0226 0.051
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0029 0.0254 0.1845
Onchocerca volvulus 0.0017 0.0099 0.0162
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0256 0.1863
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.1245 0.4439
Onchocerca volvulus 0.0017 0.0099 0.0162
Brugia malayi sodium-independent organic anion transporter family protein 0.0027 0.0232 0.0523
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0339 0.1108
Loa Loa (eye worm) multidrug resistance-associated protein 0.0013 0.0057 0.0109
Trichomonas vaginalis abcb9, putative 0.0029 0.0254 0.1845
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0029 0.0254 0.0796
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0256 0.1863
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0129 0.0129
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0014 0.0031
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0027
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0515 0.3982
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0033 0.0022
Plasmodium vivax vivapain-2 0.0017 0.0099 0.2031
Onchocerca volvulus 0.0017 0.0099 0.0162
Loa Loa (eye worm) hypothetical protein 0.0012 0.0046 0.0088
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0014 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0129 0.0291
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0129 0.0291
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0124 0.0279
Entamoeba histolytica ABC transporter, putative 0.0025 0.02 0.1396
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0099 0.0568

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) 0 Depletion of cytochrome c in mitochondria of human KB cells at 2.0 uM ChEMBL. 18040043

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.